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  Supplementary to:
  Discovery of influenza A virus sequence pairs and their combinations for simultaneous heterosubtypic targeting that hedge against antiviral resistance
 
 
Keng Boon Wee, Raphael Tze Chuen Lee, Jing Lin, Zacharias Aloysius Dwi Pramono, Sebastian Maurer-Stroh
 
An introductory video about this study:
 
 
Overview of 5 resource files:
 
Data-source.7zContains uid2Zsequence_consolidated.txt, strainname-subtype-segment-accessionurl.txt & 12 {subtype}-strainnames2-date-and-uids.txt files.
 
Full-segment-consensus.txtThe full segment consensus sequence of segments 1, 2, 3, 5, 7, and 8 for H1N1, PD09, H3N2, H5N1 and H7N9 subtypes.
 
5-S_Results.7zContains 5S-Hits, 5S-targetSequences.txt, 5S-targetSequences_noDNAHits.txt, 5S-targetSequences_noRNAHits.txt, 5S-EffectiveDuals.txt, 5S-EffectiveDuals_noDNAHits.txt, 5S-EffectiveDuals_noRNAHits.txt, 5S-EffectiveDoubles.txt, 5S-EffectiveDoubles_noDNAHits.txt, 5S-EffectiveDoubles_noRNAHits.txt, 5S-bindingAccessibilites.txt and 5S-Hits_TissueExpressions.
 
3-S_Results.7zContains 3S-Hits, 3S-targetSequences.txt, 3S-targetSequences_noDNAHits.txt, 3S-targetSequences_noRNAHits.txt, 3S-EffectiveDuals.txt, 3S-EffectiveDuals_noDNAHits.txt, 3S-EffectiveDuals_noRNAHits.txt, 3S-EffectiveDoubles.txt, 3S-EffectiveDoubles_noDNAHits.txt, 3S-EffectiveDoubles_noRNAHits.txt, 3S-bindingAccessibilites.txt and 3S-Hits_TissueExpressions.
 
gisaid_acknowledge.txtWe will like to acknowledge all the authors and submitters of the influenza sequences whom have made this work possible. The detailed list of GISAID accessions used and the contributors to these sequences could be found here.
 
 

Institue of High Performance Computing & Bioinformatics Institute, are members of A*STAR's Science and Engineering, and Biomedical Sciences Research Institutes.
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