hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                   /home/wongwc/DOMERR/bin/phase6/HMMmodels/globalmode-hmmpfam/PF04147.4_Nop14-like_family.hmmmodel [PF04147.4_Nop14-like_family]
Sequence database:          /home/wongwc/DOMERR/data/nr-05-04-2010.fasta
per-sequence score cutoff:  [none]
per-domain score cutoff:    [none]
per-sequence Eval cutoff:   <= 10        
per-domain Eval cutoff:     [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM:   PF04147.4_Nop14-like_family
Accession:   [none]
Description: [none]
  [HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence                             Description        Score    E-value  N 
--------                             -----------        -----    ------- ---
gi|6730652|gb|AAF27073.1|AC008262_22 F4N2.4 [Arabidop  1917.2          0   1
gi|15221597|ref|NP_177070.1|         unknown protein   1831.7          0   1
gi|24647702|ref|NP_652040.2|         lethal (3) 07882  1762.1          0   1
gi|19113534|ref|NP_596742.1|         U3 snoRNP protei  1741.6          0   1
gi|195570117|ref|XP_002103055.1|     GD20226 [Drosoph  1670.2          0   1
gi|194900416|ref|XP_001979753.1|     GG16769 [Drosoph  1669.7          0   1
gi|6320053|ref|NP_010133.1|          Nop14p [Saccharo  1625.6          0   1
gi|195497392|ref|XP_002096079.1|     GE25264 [Drosoph  1623.0          0   1
gi|190405151|gb|EDV08418.1|          nucleolar comple  1622.5          0   1
gi|151941853|gb|EDN60209.1|          U3 snoRNP protei  1617.8          0   1
gi|256273589|gb|EEU08522.1|          Nop14p [Saccharo  1612.5          0   1
gi|207347062|gb|EDZ73369.1|          YDL148Cp-like pr  1600.1          0   1
gi|194745272|ref|XP_001955112.1|     GF18606 [Drosoph  1421.3          0   1
gi|195144178|ref|XP_002013073.1|     GL23927 [Drosoph  1305.2          0   1
gi|125774125|ref|XP_001358321.1|     GA19157 [Drosoph  1298.0          0   1
gi|195055991|ref|XP_001994896.1|     GH17488 [Drosoph  1296.5          0   1
gi|195970395|gb|ACG60683.1|          unknown protein   1272.0          0   1
gi|195453284|ref|XP_002073720.1|     GK12987 [Drosoph  1270.7          0   1
gi|195391536|ref|XP_002054416.1|     GJ22818 [Drosoph  1261.8          0   1
gi|195349083|ref|XP_002041076.1|     GM15357 [Drosoph  1250.7          0   1
gi|213408040|ref|XP_002174791.1|     U3 snoRNP protei   825.7   2.8e-245   1
gi|225423408|ref|XP_002273322.1|     PREDICTED: hypot   809.0   3.1e-240   1
gi|270240090|emb|CBI27323.1|         unnamed protein    801.3   6.5e-238   1
gi|50291321|ref|XP_448093.1|         unnamed protein    796.7   1.5e-236   1
gi|255552772|ref|XP_002517429.1|     nop14, putative    788.9   3.3e-234   1
gi|156838843|ref|XP_001643120.1|     hypothetical pro   784.1   9.7e-233   1
gi|254584238|ref|XP_002497687.1|     ZYRO0F11242p [Zy   755.6   3.6e-224   1
gi|218193267|gb|EEC75694.1|          hypothetical pro   755.3   4.5e-224   1
gi|28570320|gb|AAN08225.2|           unknown protein    754.1     1e-223   1
gi|115454017|ref|NP_001050609.1|     Os03g0598200 [Or   750.4   1.3e-222   1
gi|50305939|ref|XP_452930.1|         unnamed protein    739.9   1.9e-219   1
gi|125587033|gb|EAZ27697.1|          hypothetical pro   728.9   3.9e-216   1
gi|242033739|ref|XP_002464264.1|     hypothetical pro   726.0     3e-215   1
gi|255719352|ref|XP_002555956.1|     KLTH0H01782p [La   719.4   2.8e-213   1
gi|45187945|ref|NP_984168.1|         ADR072Cp [Ashbya   708.6   4.9e-210   1
gi|108709667|gb|ABF97462.1|          Nop14-like famil   626.0   3.7e-185   1
gi|168018956|ref|XP_001762011.1|     predicted protei   608.0   9.9e-180   1
gi|170091488|ref|XP_001876966.1|     predicted protei   574.3   1.4e-169   1
gi|91090988|ref|XP_974875.1|         PREDICTED: simil   571.8   7.6e-169   1
gi|114158701|ref|NP_083554.2|        nucleolar protei   566.0   4.3e-167   1
gi|148705517|gb|EDL37464.1|          RIKEN cDNA 26100   566.0   4.3e-167   1
gi|70983404|ref|XP_747229.1|         rRNA maturation    564.5   1.2e-166   1
gi|118090714|ref|XP_420824.2|        PREDICTED: simil   562.4   5.3e-166   1
gi|149047414|gb|EDM00084.1|          similar to 26100   557.2     2e-164   1
gi|115490987|ref|XP_001210121.1|     conserved hypoth   556.6   2.8e-164   1
gi|121719657|ref|XP_001276527.1|     rRNA maturation    555.9   4.7e-164   1
gi|56404627|sp|Q8R3N1.1|NOP14_MOUSE  RecName: Full=Nu   554.8     1e-163   1
gi|156554877|ref|XP_001606853.1|     PREDICTED: simil   552.3   5.7e-163   1
gi|238845368|gb|EEQ35030.1|          nucleolar comple   551.9   7.3e-163   1
gi|126332163|ref|XP_001373584.1|     PREDICTED: simil   550.9   1.5e-162   1
gi|212541386|ref|XP_002150848.1|     rRNA maturation    548.2     1e-161   1
gi|119484134|ref|XP_001261970.1|     rRNA maturation    548.0   1.1e-161   1
gi|169861869|ref|XP_001837568.1|     hypothetical pro   545.7   5.3e-161   1
gi|149756960|ref|XP_001489859.1|     PREDICTED: nucle   543.9   1.9e-160   1
gi|154301059|ref|XP_001550943.1|     hypothetical pro   541.7   8.8e-160   1
gi|58262956|ref|XP_568888.1|         hypothetical pro   541.0   1.5e-159   1
gi|119602895|gb|EAW82489.1|          chromosome 4 ope   540.2   2.5e-159   1
gi|55769587|ref|NP_003694.1|         probable nucleol   540.1   2.6e-159   1
gi|2792366|gb|AAB97011.1|            unknown protein    540.1   2.6e-159   1
gi|224050190|ref|XP_002195362.1|     PREDICTED: simil   539.6   3.8e-159   1
gi|114592956|ref|XP_001151808.1|     PREDICTED: hypot   538.4   8.7e-159   1
gi|158259339|dbj|BAF85628.1|         unnamed protein    537.3   1.8e-158   1
gi|156405559|ref|XP_001640799.1|     predicted protei   533.9   1.9e-157   1
gi|156056817|ref|XP_001594332.1|     hypothetical pro   530.9   1.5e-156   1
gi|66550520|ref|XP_397160.2|         PREDICTED: simil   530.2   2.6e-156   1
gi|149642709|ref|NP_001092466.1|     probable nucleol   529.7   3.7e-156   1
gi|73951769|ref|XP_536223.2|         PREDICTED: simil   527.3   1.9e-155   1
gi|261201764|ref|XP_002628096.1|     rRNA maturation    527.2   2.1e-155   1
gi|225558305|gb|EEH06589.1|          nucleolar comple   527.0   2.3e-155   1
gi|291245101|ref|XP_002742430.1|     PREDICTED: Nucle   526.9   2.6e-155   1
gi|239611906|gb|EEQ88893.1|          rRNA maturation    525.9   5.1e-155   1
gi|147778528|emb|CAN71711.1|         hypothetical pro   523.9   1.9e-154   1
gi|240110482|gb|EER28640.1|          Nop14-like famil   523.2   3.2e-154   1
gi|119195743|ref|XP_001248475.1|     hypothetical pro   521.2   1.3e-153   1
gi|154285976|ref|XP_001543783.1|     conserved hypoth   519.9   3.2e-153   1
gi|281340003|gb|EFB15587.1|          hypothetical pro   519.1   5.8e-153   1
gi|240277261|gb|EER40770.1|          nucleolar comple   516.8   2.8e-152   1
gi|157138692|ref|XP_001657340.1|     nop14 [Aedes aeg   515.0   9.4e-152   1
gi|213513131|ref|NP_001133389.1|     Nucleolar protei   514.5   1.4e-151   1
gi|238508485|ref|XP_002385435.1|     rRNA maturation    512.7   4.8e-151   1
gi|169784386|ref|XP_001826654.1|     hypothetical pro   507.3   1.9e-149   1
gi|242798865|ref|XP_002483256.1|     rRNA maturation    506.7     3e-149   1
gi|291188514|gb|EFE43850.1|          hypothetical pro   505.9   5.3e-149   1
gi|255954791|ref|XP_002568148.1|     Pc21g11160 [Peni   504.7   1.2e-148   1
gi|258575579|ref|XP_002541971.1|     conserved hypoth   502.8   4.4e-148   1
gi|291178786|gb|EFE34574.1|          hypothetical pro   500.5   2.2e-147   1
gi|51467886|ref|NP_001003831.1|      NOP14 nucleolar    498.9   6.7e-147   1
gi|55249633|gb|AAH85643.1|           NOP14 nucleolar    497.2   2.3e-146   1
gi|226290909|gb|EEH46337.1|          nucleolar comple   494.0   2.1e-145   1
gi|67521954|ref|XP_659038.1|         hypothetical pro   488.9     7e-144   1
gi|225679198|gb|EEH17482.1|          nucleolar protei   488.0   1.3e-143   1
gi|71005582|ref|XP_757457.1|         hypothetical pro   487.8   1.5e-143   1
gi|226278062|gb|EEH33628.1|          nucleolar comple   485.6   6.9e-143   1
gi|171687505|ref|XP_001908693.1|     unnamed protein    485.2   8.7e-143   1
gi|145253342|ref|XP_001398184.1|     hypothetical pro   485.0     1e-142   1
gi|289621371|emb|CBI52154.1|         unnamed protein    477.9   1.4e-140   1
gi|254573674|ref|XP_002493946.1|     Nucleolar protei   477.3   2.1e-140   1
gi|116180704|ref|XP_001220201.1|     hypothetical pro   473.9   2.3e-139   1
gi|50555500|ref|XP_505158.1|         YALI0F08371p [Ya   471.1   1.6e-138   1
gi|256732640|gb|EEU45988.1|          hypothetical pro   462.4   6.4e-136   1
gi|170047157|ref|XP_001851100.1|     nop14 [Culex qui   450.7   2.2e-132   1
gi|260948394|ref|XP_002618494.1|     hypothetical pro   434.3   1.9e-127   1
gi|150866880|ref|XP_001386622.2|     Probable nucleol   426.1   5.5e-125   1
gi|261356226|gb|EEY18654.1|          nucleolar comple   425.3   9.8e-125   1
gi|190345785|gb|EDK37729.2|          hypothetical pro   423.5   3.3e-124   1
gi|146420400|ref|XP_001486156.1|     hypothetical pro   421.9     1e-123   1
gi|50416593|ref|XP_457562.1|         hypothetical pro   413.8   2.9e-121   1
gi|199429947|emb|CAG85573.2|         DEHA2B14190p [De   413.8   2.9e-121   1
gi|74180014|dbj|BAE36550.1|          unnamed protein    412.2   8.7e-121   1
gi|241953351|ref|XP_002419397.1|     U3 small nucleol   402.4   7.8e-118   1
gi|19684184|gb|AAH26035.1|           NOP14 protein [H   397.0   3.2e-116   1
gi|119602896|gb|EAW82490.1|          chromosome 4 ope   396.9   3.4e-116   1
gi|145603109|ref|XP_362025.2|        hypothetical pro   396.4   4.9e-116   1
gi|68465617|ref|XP_723170.1|         potential small    395.2   1.1e-115   1
gi|119602899|gb|EAW82493.1|          chromosome 4 ope   394.7   1.6e-115   1
gi|238880894|gb|EEQ44532.1|          conserved hypoth   394.1   2.4e-115   1
gi|169603327|ref|XP_001795085.1|     hypothetical pro   387.8   1.9e-113   1
gi|164657706|ref|XP_001729979.1|     hypothetical pro   385.3   1.1e-112   1
gi|114592952|ref|XP_526506.2|        PREDICTED: proba   384.7   1.6e-112   1
gi|262105033|gb|EEY63085.1|          nucleolar protei   382.9   5.5e-112   1
gi|189203035|ref|XP_001937853.1|     nucleolar protei   380.7   2.7e-111   1
gi|193643702|ref|XP_001950397.1|     PREDICTED: simil   378.0   1.7e-110   1
gi|149241272|ref|XP_001526295.1|     conserved hypoth   372.4   8.3e-109   1
gi|198428459|ref|XP_002128116.1|     PREDICTED: simil   349.9   4.7e-102   1
gi|260793149|ref|XP_002591575.1|     hypothetical pro   326.5    5.5e-95   1
gi|241822923|ref|XP_002416603.1|     nop14, putative    312.2    1.1e-90   1
gi|47215158|emb|CAG12449.1|          unnamed protein    301.6    1.7e-87   1
gi|115928458|ref|XP_784009.2|        PREDICTED: simil   300.1    4.8e-87   1
gi|145351375|ref|XP_001420056.1|     predicted protei   286.5    5.8e-83   1
gi|116059907|emb|CAL55966.1|         Nucleolar protei   265.3    1.4e-76   1
gi|281200779|gb|EFA74997.1|          U3 snoRNP protei   260.1    5.4e-75   1
gi|242019819|ref|XP_002430356.1|     nop14, putative    254.1    3.3e-73   1
gi|66806907|ref|XP_637176.1|         U3 snoRNP protei   251.6      2e-72   1
gi|114592954|ref|XP_001151429.1|     PREDICTED: proba   250.1    5.3e-72   1
gi|119113792|ref|XP_310703.3|        AGAP000397-PA [A   238.3    1.9e-68   1
gi|167516260|ref|XP_001742471.1|     hypothetical pro   237.1    4.4e-68   1
gi|1843399|dbj|BAA19121.1|           unnamed protein    231.7    1.8e-66   1
gi|149047413|gb|EDM00083.1|          similar to 26100   226.1    9.3e-65   1
gi|196009480|ref|XP_002114605.1|     hypothetical pro   218.4    1.9e-62   1
gi|25143366|ref|NP_740774.1|         hypothetical pro   216.5    6.9e-62   1
gi|268563498|ref|XP_002638852.1|     Hypothetical pro   207.3    4.1e-59   1
gi|157822351|ref|NP_001099483.1|     nucleolar protei   204.3    3.3e-58   1
gi|159476980|ref|XP_001696589.1|     nucleolar protei   170.1    6.3e-48   1
gi|170585404|ref|XP_001897474.1|     hypothetical pro   151.1    3.3e-42   1
gi|195110695|ref|XP_001999915.1|     GI22817 [Drosoph    49.2    1.6e-11   1
gi|255726222|ref|XP_002548037.1|     hypothetical pro    30.5    6.9e-06   1
gi|226453879|gb|EEH51187.1|          predicted protei    17.7      0.049   1
gi|224012905|ref|XP_002295105.1|     predicted protei    11.8       0.33   1
gi|219121013|ref|XP_002185738.1|     predicted protei    -1.2       0.39   1
gi|195110697|ref|XP_001999916.1|     GI22816 [Drosoph   -41.5       0.66   1
gi|224111890|ref|XP_002316014.1|     predicted protei   -95.8        1.3   1
gi|239871791|gb|EER01571.1|          Troponin T, skel  -108.9        1.6   1
gi|255082726|ref|XP_002504349.1|     predicted protei  -113.2        1.7   1
gi|221116928|ref|XP_002161686.1|     PREDICTED: simil  -114.5        1.7   1
gi|239888371|gb|EER11103.1|          nop14, putative   -119.2        1.8   1
gi|195099677|ref|XP_001997981.1|     GH11720 [Drosoph  -158.4        3.1   1
gi|33874764|gb|AAH09760.2|           NOP14 protein [H  -191.2        4.7   1
gi|66361603|ref|XP_627325.1|         conserved protei  -212.4        6.3   1
gi|67594925|ref|XP_665952.1|         hypothetical pro  -213.6        6.3   1
gi|71746130|ref|XP_822264.1|         hypothetical pro  -238.4        8.8   1

Parsed for domains:
Sequence                             Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------                             ------- ----- -----    ----- -----      -----  -------
gi|6730652|gb|AAF27073.1|AC008262_22   1/1      20   876 ..     1   927 []  1917.2        0
gi|15221597|ref|NP_177070.1|           1/1      20   886 ..     1   927 []  1831.7        0
gi|24647702|ref|NP_652040.2|           1/1      27   840 ..     1   927 []  1762.1        0
gi|19113534|ref|NP_596742.1|           1/1      36   827 .]     1   927 []  1741.6        0
gi|195570117|ref|XP_002103055.1|       1/1      27   839 ..     1   927 []  1670.2        0
gi|194900416|ref|XP_001979753.1|       1/1      27   839 ..     1   927 []  1669.7        0
gi|6320053|ref|NP_010133.1|            1/1      37   795 ..     1   927 []  1625.6        0
gi|195497392|ref|XP_002096079.1|       1/1      27   839 ..     1   927 []  1623.0        0
gi|190405151|gb|EDV08418.1|            1/1      37   795 ..     1   927 []  1622.5        0
gi|151941853|gb|EDN60209.1|            1/1      37   795 ..     1   927 []  1617.8        0
gi|256273589|gb|EEU08522.1|            1/1      37   795 ..     1   927 []  1612.5        0
gi|207347062|gb|EDZ73369.1|            1/1       3   757 ..     1   927 []  1600.1        0
gi|194745272|ref|XP_001955112.1|       1/1      27   844 ..     1   927 []  1421.3        0
gi|195144178|ref|XP_002013073.1|       1/1      27   842 ..     1   927 []  1305.2        0
gi|125774125|ref|XP_001358321.1|       1/1      27   842 ..     1   927 []  1298.0        0
gi|195055991|ref|XP_001994896.1|       1/1       9   842 ..     1   927 []  1296.5        0
gi|195970395|gb|ACG60683.1|            1/1      21   863 ..     1   927 []  1272.0        0
gi|195453284|ref|XP_002073720.1|       1/1      30   853 ..     1   927 []  1270.7        0
gi|195391536|ref|XP_002054416.1|       1/1       9   842 ..     1   927 []  1261.8        0
gi|195349083|ref|XP_002041076.1|       1/1       2   753 ..     1   927 []  1250.7        0
gi|213408040|ref|XP_002174791.1|       1/1      37   832 .]     1   927 []   825.7 2.8e-245
gi|225423408|ref|XP_002273322.1|       1/1      26   960 ..     1   927 []   809.0 3.1e-240
gi|270240090|emb|CBI27323.1|           1/1       1   886 [.     1   927 []   801.3 6.5e-238
gi|50291321|ref|XP_448093.1|           1/1      35   784 ..     1   927 []   796.7 1.5e-236
gi|255552772|ref|XP_002517429.1|       1/1       2   852 ..     1   927 []   788.9 3.3e-234
gi|156838843|ref|XP_001643120.1|       1/1      36   792 ..     1   927 []   784.1 9.7e-233
gi|254584238|ref|XP_002497687.1|       1/1      57   804 ..     1   927 []   755.6 3.6e-224
gi|218193267|gb|EEC75694.1|            1/1      32   934 ..     1   927 []   755.3 4.5e-224
gi|28570320|gb|AAN08225.2|             1/1      32   939 ..     1   927 []   754.1   1e-223
gi|115454017|ref|NP_001050609.1|       1/1       5   899 ..     1   927 []   750.4 1.3e-222
gi|50305939|ref|XP_452930.1|           1/1      36   822 ..     1   927 []   739.9 1.9e-219
gi|125587033|gb|EAZ27697.1|            1/1      32   938 ..     1   927 []   728.9 3.9e-216
gi|242033739|ref|XP_002464264.1|       1/1      27   910 ..     1   927 []   726.0   3e-215
gi|255719352|ref|XP_002555956.1|       1/1      35   799 ..     1   927 []   719.4 2.8e-213
gi|45187945|ref|NP_984168.1|           1/1      34   791 ..     1   927 []   708.6 4.9e-210
gi|108709667|gb|ABF97462.1|            1/1      32   916 ..     1   927 []   626.0 3.7e-185
gi|168018956|ref|XP_001762011.1|       1/1      25   927 ..     1   927 []   608.0 9.9e-180
gi|170091488|ref|XP_001876966.1|       1/1      38   886 ..     1   927 []   574.3 1.4e-169
gi|91090988|ref|XP_974875.1|           1/1       2   790 ..     1   927 []   571.8 7.6e-169
gi|114158701|ref|NP_083554.2|          1/1      19   850 ..     1   927 []   566.0 4.3e-167
gi|148705517|gb|EDL37464.1|            1/1      27   858 ..     1   927 []   566.0 4.3e-167
gi|70983404|ref|XP_747229.1|           1/1      37   898 ..     1   927 []   564.5 1.2e-166
gi|118090714|ref|XP_420824.2|          1/1      14   868 ..     1   927 []   562.4 5.3e-166
gi|149047414|gb|EDM00084.1|            1/1      19   852 ..     1   927 []   557.2   2e-164
gi|115490987|ref|XP_001210121.1|       1/1      37   898 ..     1   927 []   556.6 2.8e-164
gi|121719657|ref|XP_001276527.1|       1/1      37   898 ..     1   927 []   555.9 4.7e-164
gi|56404627|sp|Q8R3N1.1|NOP14_MOUSE    1/1      19   850 ..     1   927 []   554.8   1e-163
gi|156554877|ref|XP_001606853.1|       1/1      13   897 ..     1   927 []   552.3 5.7e-163
gi|238845368|gb|EEQ35030.1|            1/1      37   886 ..     1   927 []   551.9 7.3e-163
gi|126332163|ref|XP_001373584.1|       1/1     137   972 ..     1   927 []   550.9 1.5e-162
gi|212541386|ref|XP_002150848.1|       1/1      36   902 ..     1   927 []   548.2   1e-161
gi|119484134|ref|XP_001261970.1|       1/1      37   899 ..     1   927 []   548.0 1.1e-161
gi|169861869|ref|XP_001837568.1|       1/1      39   892 ..     1   927 []   545.7 5.3e-161
gi|149756960|ref|XP_001489859.1|       1/1      22   843 ..     1   927 []   543.9 1.9e-160
gi|154301059|ref|XP_001550943.1|       1/1      34   899 ..     1   927 []   541.7 8.8e-160
gi|58262956|ref|XP_568888.1|           1/1      37   916 ..     1   927 []   541.0 1.5e-159
gi|119602895|gb|EAW82489.1|            1/1      19   847 ..     1   927 []   540.2 2.5e-159
gi|55769587|ref|NP_003694.1|           1/1      19   847 ..     1   927 []   540.1 2.6e-159
gi|2792366|gb|AAB97011.1|              1/1      35   863 ..     1   927 []   540.1 2.6e-159
gi|224050190|ref|XP_002195362.1|       1/1      14   855 ..     1   927 []   539.6 3.8e-159
gi|114592956|ref|XP_001151808.1|       1/1      19   847 ..     1   927 []   538.4 8.7e-159
gi|158259339|dbj|BAF85628.1|           1/1      19   847 ..     1   927 []   537.3 1.8e-158
gi|156405559|ref|XP_001640799.1|       1/1       9   848 ..     1   927 []   533.9 1.9e-157
gi|156056817|ref|XP_001594332.1|       1/1      34   899 ..     1   927 []   530.9 1.5e-156
gi|66550520|ref|XP_397160.2|           1/1      19   826 ..     1   927 []   530.2 2.6e-156
gi|149642709|ref|NP_001092466.1|       1/1      21   859 ..     1   927 []   529.7 3.7e-156
gi|73951769|ref|XP_536223.2|           1/1     149   979 ..     1   927 []   527.3 1.9e-155
gi|261201764|ref|XP_002628096.1|       1/1      37   889 ..     1   927 []   527.2 2.1e-155
gi|225558305|gb|EEH06589.1|            1/1      37   889 ..     1   927 []   527.0 2.3e-155
gi|291245101|ref|XP_002742430.1|       1/1      17   869 ..     1   927 []   526.9 2.6e-155
gi|239611906|gb|EEQ88893.1|            1/1      37   889 ..     1   927 []   525.9 5.1e-155
gi|147778528|emb|CAN71711.1|           1/1       2   802 ..     1   927 []   523.9 1.9e-154
gi|240110482|gb|EER28640.1|            1/1      40   881 ..     1   927 []   523.2 3.2e-154
gi|119195743|ref|XP_001248475.1|       1/1      40   880 ..     1   927 []   521.2 1.3e-153
gi|154285976|ref|XP_001543783.1|       1/1      37   889 ..     1   927 []   519.9 3.2e-153
gi|281340003|gb|EFB15587.1|            1/1       1   817 [.     1   927 []   519.1 5.8e-153
gi|240277261|gb|EER40770.1|            1/1      37   889 ..     1   927 []   516.8 2.8e-152
gi|157138692|ref|XP_001657340.1|       1/1      10   835 ..     1   927 []   515.0 9.4e-152
gi|213513131|ref|NP_001133389.1|       1/1       9   846 ..     1   927 []   514.5 1.4e-151
gi|238508485|ref|XP_002385435.1|       1/1      37   898 ..     1   927 []   512.7 4.8e-151
gi|169784386|ref|XP_001826654.1|       1/1      37   898 ..     1   927 []   507.3 1.9e-149
gi|242798865|ref|XP_002483256.1|       1/1      41   904 ..     1   927 []   506.7   3e-149
gi|291188514|gb|EFE43850.1|            1/1      37   876 ..     1   927 []   505.9 5.3e-149
gi|255954791|ref|XP_002568148.1|       1/1      37   897 ..     1   927 []   504.7 1.2e-148
gi|258575579|ref|XP_002541971.1|       1/1      40   881 ..     1   927 []   502.8 4.4e-148
gi|291178786|gb|EFE34574.1|            1/1      37   851 ..     1   927 []   500.5 2.2e-147
gi|51467886|ref|NP_001003831.1|        1/1      13   850 ..     1   927 []   498.9 6.7e-147
gi|55249633|gb|AAH85643.1|             1/1      13   851 ..     1   927 []   497.2 2.3e-146
gi|226290909|gb|EEH46337.1|            1/1      40   891 ..     1   927 []   494.0 2.1e-145
gi|67521954|ref|XP_659038.1|           1/1      37   898 ..     1   927 []   488.9   7e-144
gi|225679198|gb|EEH17482.1|            1/1      40   891 ..     1   927 []   488.0 1.3e-143
gi|71005582|ref|XP_757457.1|           1/1      43   964 ..     1   927 []   487.8 1.5e-143
gi|226278062|gb|EEH33628.1|            1/1      40   891 ..     1   927 []   485.6 6.9e-143
gi|171687505|ref|XP_001908693.1|       1/1      38   897 ..     1   927 []   485.2 8.7e-143
gi|145253342|ref|XP_001398184.1|       1/1      37   865 ..     1   927 []   485.0   1e-142
gi|289621371|emb|CBI52154.1|           1/1      38   893 ..     1   927 []   477.9 1.4e-140
gi|254573674|ref|XP_002493946.1|       1/1      40   805 ..     1   927 []   477.3 2.1e-140
gi|116180704|ref|XP_001220201.1|       1/1      38   897 ..     1   927 []   473.9 2.3e-139
gi|50555500|ref|XP_505158.1|           1/1      34   817 ..     1   927 []   471.1 1.6e-138
gi|256732640|gb|EEU45988.1|            1/1      34   890 ..     1   927 []   462.4 6.4e-136
gi|170047157|ref|XP_001851100.1|       1/1       8   831 ..     1   927 []   450.7 2.2e-132
gi|260948394|ref|XP_002618494.1|       1/1      36   783 ..     1   927 []   434.3 1.9e-127
gi|150866880|ref|XP_001386622.2|       1/1      35   809 ..     1   927 []   426.1 5.5e-125
gi|261356226|gb|EEY18654.1|            1/1      39   879 ..     1   927 []   425.3 9.8e-125
gi|190345785|gb|EDK37729.2|            1/1      35   761 ..     1   927 []   423.5 3.3e-124
gi|146420400|ref|XP_001486156.1|       1/1      35   761 ..     1   927 []   421.9   1e-123
gi|50416593|ref|XP_457562.1|           1/1      35   781 ..     1   927 []   413.8 2.9e-121
gi|199429947|emb|CAG85573.2|           1/1      62   808 ..     1   927 []   413.8 2.9e-121
gi|74180014|dbj|BAE36550.1|            1/1      19   786 ..     1   927 []   412.2 8.7e-121
gi|241953351|ref|XP_002419397.1|       1/1      42   818 ..     1   927 []   402.4 7.8e-118
gi|19684184|gb|AAH26035.1|             1/1      19   796 ..     1   927 []   397.0 3.2e-116
gi|119602896|gb|EAW82490.1|            1/1      19   796 ..     1   927 []   396.9 3.4e-116
gi|145603109|ref|XP_362025.2|          1/1      32   869 ..     1   927 []   396.4 4.9e-116
gi|68465617|ref|XP_723170.1|           1/1      43   828 ..     1   927 []   395.2 1.1e-115
gi|119602899|gb|EAW82493.1|            1/1      19   800 ..     1   927 []   394.7 1.6e-115
gi|238880894|gb|EEQ44532.1|            1/1      43   824 ..     1   927 []   394.1 2.4e-115
gi|169603327|ref|XP_001795085.1|       1/1      83   875 ..     1   927 []   387.8 1.9e-113
gi|164657706|ref|XP_001729979.1|       1/1      42   945 ..     1   927 []   385.3 1.1e-112
gi|114592952|ref|XP_526506.2|          1/1      19   784 ..     1   927 []   384.7 1.6e-112
gi|262105033|gb|EEY63085.1|            1/1      22   831 ..     1   927 []   382.9 5.5e-112
gi|189203035|ref|XP_001937853.1|       1/1      34   819 ..     1   927 []   380.7 2.7e-111
gi|193643702|ref|XP_001950397.1|       1/1       2   805 ..     1   927 []   378.0 1.7e-110
gi|149241272|ref|XP_001526295.1|       1/1      37   850 ..     1   927 []   372.4 8.3e-109
gi|198428459|ref|XP_002128116.1|       1/1      23   848 ..     1   927 []   349.9 4.7e-102
gi|260793149|ref|XP_002591575.1|       1/1       9   768 ..     1   927 []   326.5  5.5e-95
gi|241822923|ref|XP_002416603.1|       1/1      14   843 ..     1   927 []   312.2  1.1e-90
gi|47215158|emb|CAG12449.1|            1/1       2   862 ..     1   927 []   301.6  1.7e-87
gi|115928458|ref|XP_784009.2|          1/1      12   694 ..     1   927 []   300.1  4.8e-87
gi|145351375|ref|XP_001420056.1|       1/1      30   951 ..     1   927 []   286.5  5.8e-83
gi|116059907|emb|CAL55966.1|           1/1       2   930 ..     1   927 []   265.3  1.4e-76
gi|281200779|gb|EFA74997.1|            1/1      24   951 ..     1   927 []   260.1  5.4e-75
gi|242019819|ref|XP_002430356.1|       1/1       8   787 ..     1   927 []   254.1  3.3e-73
gi|66806907|ref|XP_637176.1|           1/1       5   970 ..     1   927 []   251.6    2e-72
gi|114592954|ref|XP_001151429.1|       1/1      19   675 .]     1   927 []   250.1  5.3e-72
gi|119113792|ref|XP_310703.3|          1/1      20   818 ..     1   927 []   238.3  1.9e-68
gi|167516260|ref|XP_001742471.1|       1/1      19   854 ..     1   927 []   237.1  4.4e-68
gi|1843399|dbj|BAA19121.1|             1/1       1   708 [.     1   927 []   231.7  1.8e-66
gi|149047413|gb|EDM00083.1|            1/1      19   653 .]     1   927 []   226.1  9.3e-65
gi|196009480|ref|XP_002114605.1|       1/1       9   801 ..     1   927 []   218.4  1.9e-62
gi|25143366|ref|NP_740774.1|           1/1       1   797 [.     1   927 []   216.5  6.9e-62
gi|268563498|ref|XP_002638852.1|       1/1       1   790 [.     1   927 []   207.3  4.1e-59
gi|157822351|ref|NP_001099483.1|       1/1      19   639 ..     1   927 []   204.3  3.3e-58
gi|159476980|ref|XP_001696589.1|       1/1      17  1120 ..     1   927 []   170.1  6.3e-48
gi|170585404|ref|XP_001897474.1|       1/1      11   763 ..     1   927 []   151.1  3.3e-42
gi|195110695|ref|XP_001999915.1|       1/1       1   416 [.     1   927 []    49.2  1.6e-11
gi|255726222|ref|XP_002548037.1|       1/1       1   544 [.     1   927 []    30.5  6.9e-06
gi|226453879|gb|EEH51187.1|            1/1       2  1046 ..     1   927 []    17.7    0.049
gi|224012905|ref|XP_002295105.1|       1/1      40  1094 ..     1   927 []    11.8     0.33
gi|219121013|ref|XP_002185738.1|       1/1      10   959 ..     1   927 []    -1.2     0.39
gi|195110697|ref|XP_001999916.1|       1/1       9   421 .]     1   927 []   -41.5     0.66
gi|224111890|ref|XP_002316014.1|       1/1      28   620 .]     1   927 []   -95.8      1.3
gi|239871791|gb|EER01571.1|            1/1      11   776 ..     1   927 []  -108.9      1.6
gi|255082726|ref|XP_002504349.1|       1/1       1   578 []     1   927 []  -113.2      1.7
gi|221116928|ref|XP_002161686.1|       1/1       9   627 ..     1   927 []  -114.5      1.7
gi|239888371|gb|EER11103.1|            1/1      11   774 ..     1   927 []  -119.2      1.8
gi|195099677|ref|XP_001997981.1|       1/1       1   339 []     1   927 []  -158.4      3.1
gi|33874764|gb|AAH09760.2|             1/1       1   468 []     1   927 []  -191.2      4.7
gi|66361603|ref|XP_627325.1|           1/1      40   959 ..     1   927 []  -212.4      6.3
gi|67594925|ref|XP_665952.1|           1/1      20   963 ..     1   927 []  -213.6      6.3
gi|71746130|ref|XP_822264.1|           1/1     170   897 ..     1   927 []  -238.4      8.8

Alignments of top-scoring domains:
gi|6730652|gb|AAF27073.1|AC008262_22: domain 1 of 1, from 20 to 876: score 1917.2, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K    ak+qk++NPF++++++rKFdilG+   k+Kgee++
  gi|6730652    20    GPDAVAMK----AKTQKVDNPFESIRSRRKFDILGK---KRKGEERF 59   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   ++VSR++a++kRk+Tle+e+++++Ks++f+DkRiGE+n++L+    e++K
  gi|6730652    60 VSVSRTRAVDKRKNTLEKEYEQSLKSSVFLDKRIGEQNDELG----EFDK 105  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   +++R++R+r  Ql+L+K+++ynl+DG+EDv+edG++ggsSvKDD+Ds+++
  gi|6730652   106 GIIRSQRQR--QLKLAKKSMYNLSDGEEDVYEDGALGGSSVKDDFDSGLL 153  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   ++e+L+ddd++a+++  k++++l+r++e+DA++eee+r   KsKkEVmeE
  gi|6730652   154 SDEDLQDDDLEASAS--KRLKHLNRNREVDASGEEERR---KSKKEVMEE 198  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   iI+KSKl+++E+aK+Kee+++l+d+LD+Nfk+L++++ame+lt       
  gi|6730652   199 IIMKSKLGRMEKAKQKEEKGKLMDELDKNFKSLVNSEAMESLT------- 241  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   kp++a+e+t+++Y+l+l++M++e+RA+Ps+RTKT+EE+AqkE+ekL++LE
  gi|6730652   242 KPFVAEENTRDPYLLSLNDMSMEIRARPSERTKTPEEIAQKEREKLEALE 291  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   eeR+kRM+eteEl+dg+eEiGGEES+k+l+v+S+dDL+DsfsVEEDKPK+
  gi|6730652   292 EERKKRMQETEELSDGDEEIGGEESTKRLTVISGDDLGDSFSVEEDKPKR 341  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+i+d+leREDNvdN+E+dEd+d+e+e+++Ddd+++dG+d+kq+K+++L+
  gi|6730652   342 GWIDDVLEREDNVDNSESDEDEDSESEEEEDDDGESDGGDEKQRKGHHLE 391  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   d+E++DD+LGAELED+e e+DdEeD+dEE DaEl+v+k+LK+d+a+p+kg
  gi|6730652   392 DWEQSDDELGAELEDEE-EDDDEEDDDEE-DAELRVHKKLKNDYAAPYKG 439  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   e+++++vkeK+NmKK+++T     +r+ipF+id+Pk++eell+L++++++
  gi|6730652   440 EGLSGTVKEKTNMKKMSST-----QRDIPFMIDPPKNFEELLALVEDCSN 484  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   eD++lIV+RI++ah++K+k+eNRK+++vKF+++L+++I  L+  ++++++
  gi|6730652   485 EDVILIVNRIRIAHSIKIKAENRKKMQVKFNFALKGLI--LY--FAVLAS 530  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   kk+LNf+LL++Lv++Lie+++e+P+++ai+++++ll+++++++e++k++E
  gi|6730652   531 KKPLNFDLLNMLVKPLIEMSMEIPYFAAICARQRLLKTRSQFCEAIKNPE 580  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   ++++PSlk+L++++L++l+F++SDfrH+V+TP++llm+e+L+r+p+sS++
  gi|6730652   581 DGCWPSLKTLFLLRLWSLIFPCSDFRHAVMTPSILLMCEYLMRCPISSGR 630  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   dIaiG+fL+siVL+++  S++++++++ya++q+Lf ++++    el+s+t
  gi|6730652   631 DIAIGSFLCSIVLLTK--SHQHLRNLRYAIEQDLF-YHFM----ELKSLT 673  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL++++d            n+++v+++++l++++++ aD      +++f+
  gi|6730652   674 PLLCIQD------------NVKEVMPLNFLKIMNEP-AD------SPYFS 704  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   +d++r+S+L++  v+e++E++vei+++l++F+EIf+PI++LL++++++e+
  gi|6730652   705 SDDFRASILSS--VVETLEGFVEINGGLSSFPEIFMPISTLLHQIGNQEK 752  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   +p++ lkekl+d+++l+eK+t+d++kerKPL++++HKPvaIr+++PKFEE
  gi|6730652   753 IPQT-LKEKLEDVAKLIEKKTDDHHKERKPLSMRKHKPVAIRMVNPKFEE 801  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +P+++ +DpDk+Rs+l+KLk+klKrE++GA+RElRKD++F++++
  gi|6730652   802 NF----VPGMD-NDPDKYRSDLKKLKRKLKREARGAVRELRKDSYFMSTV 846  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ++kEkaa++qer+EK++k++++lqeqe+A+   
  gi|6730652   847 KAKEKAAHEQERAEKHGKAWAFLQEQEHAF    876  

gi|15221597|ref|NP_177070.1|: domain 1 of 1, from 20 to 886: score 1831.7, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K    ak+qk++NPF++++++rKFdilG+   k+Kgee++
  gi|1522159    20    GPDAVAMK----AKTQKVDNPFESIRSRRKFDILGK---KRKGEERF 59   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   ++VSR++a++kRk+Tle+e+++++Ks++f+DkRiGE+n++L+    e++K
  gi|1522159    60 VSVSRTRAVDKRKNTLEKEYEQSLKSSVFLDKRIGEQNDELG----EFDK 105  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   +++R++R+r  Ql+L+K+++ynl+DG+EDv+edG++ggsSvKDD+Ds+++
  gi|1522159   106 GIIRSQRQR--QLKLAKKSMYNLSDGEEDVYEDGALGGSSVKDDFDSGLL 153  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   ++e+L+ddd++a+++  k++++l+r++e+DA++eee+r   KsKkEVmeE
  gi|1522159   154 SDEDLQDDDLEASAS--KRLKHLNRNREVDASGEEERR---KSKKEVMEE 198  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   iI+KSKl+++E+aK+Kee+++l+d+LD+Nfk+L++++ame+lt       
  gi|1522159   199 IIMKSKLGRMEKAKQKEEKGKLMDELDKNFKSLVNSEAMESLT------- 241  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   kp++a+e+t+++Y+l+l++M++e+RA+Ps+RTKT+EE+AqkE+ekL++LE
  gi|1522159   242 KPFVAEENTRDPYLLSLNDMSMEIRARPSERTKTPEEIAQKEREKLEALE 291  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   eeR+kRM+eteEl+dg+eEiGGEES+k+l+v+S+dDL+DsfsVEEDKPK+
  gi|1522159   292 EERKKRMQETEELSDGDEEIGGEESTKRLTVISGDDLGDSFSVEEDKPKR 341  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+i+d+leREDNvdN+E+dEd+d+e+e+++Ddd+++dG+d+kq+K+++L+
  gi|1522159   342 GWIDDVLEREDNVDNSESDEDEDSESEEEEDDDGESDGGDEKQRKGHHLE 391  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   d+E++DD+LGAELED+e e+DdEeD+dEE DaEl+v+k+LK+d+a+p+kg
  gi|1522159   392 DWEQSDDELGAELEDEE-EDDDEEDDDEE-DAELRVHKKLKNDYAAPYKG 439  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   e+++++vkeK+NmKK+++T     +r+ipF+id+Pk++eell+L++++++
  gi|1522159   440 EGLSGTVKEKTNMKKMSST-----QRDIPFMIDPPKNFEELLALVEDCSN 484  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   eD++lIV+RI++ah++K+k+eNRK+++v F+ vLLq+        +++++
  gi|1522159   485 EDVILIVNRIRIAHSIKIKAENRKKMQV-FYGVLLQYF-------AVLAS 526  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   kk+LNf+LL++Lv++Lie+++e+P+++ai+++++ll+++++++e++k++E
  gi|1522159   527 KKPLNFDLLNMLVKPLIEMSMEIPYFAAICARQRLLKTRSQFCEAIKNPE 576  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   ++++PSlk+L++++L++l+F++SDfrH+V+TP++llm+e+L+r+p+sS++
  gi|1522159   577 DGCWPSLKTLFLLRLWSLIFPCSDFRHAVMTPSILLMCEYLMRCPISSGR 626  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiL...............f
                   dIaiG+fL+siVL+ q  Sk++ Pe + ++   L   ++++++ + +++f
  gi|1522159   627 DIAIGSFLCSIVLL-Q--SKKFCPEAILFIRTLLmaasdkkspasaeseF 673  

                   tllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrL
                    ++++    el+s+tPL++++d            n+++v+++++l+++++
  gi|1522159   674 -YHFM----ELKSLTPLLCIQD------------NVKEVMPLNFLKIMNE 706  

                   slaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIf
                   + aD      +++f++d++r+S+L++  v+e++E++vei+++l++F+EIf
  gi|1522159   707 P-AD------SPYFSSDDFRASILSS--VVETLEGFVEINGGLSSFPEIF 747  

                   lPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqe
                   +PI++LL++++++e++p++ lkekl+d+++l+eK+t+d++kerKPL++++
  gi|1522159   748 MPISTLLHQIGNQEKIPQT-LKEKLEDVAKLIEKKTDDHHKERKPLSMRK 796  

                   HKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKG
                   HKPvaIr+++PKFEEn+    +P+++ +DpDk+Rs+l+KLk+klKrE++G
  gi|1522159   797 HKPVAIRMVNPKFEENF----VPGMD-NDPDKYRSDLKKLKRKLKREARG 841  

                   AiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   A+RElRKD++F++++++kEkaa++qer+EK++k++++lqeqe+A+   
  gi|1522159   842 AVRELRKDSYFMSTVKAKEKAAHEQERAEKHGKAWAFLQEQEHAF    886  

gi|24647702|ref|NP_652040.2|: domain 1 of 1, from 27 to 840: score 1762.1, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K         ++NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|2464770    27    NSTAQSSK---------RGNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++Tl+++f++k+K+++f+D+RiG   khLsGDqL+E++
  gi|2464770    62 PGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIG---KHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r S+++a+++n  l+D+e++++rg++     l+++e+
  gi|2464770   109 MNARYLAEKMSQVR-SNQKAEKFN--LNDDELLTHRGQT-----LEEIEQ 150  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +++e+sdd+EL+deaLD+df+a+++F++e+++a+++q+        +++E
  gi|2464770   151 YRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQA--------AIDE 192  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I+++K++K+E+aKeK+ev+Dl++kLD+N+k+Ll+l+a  k+t      K
  gi|2464770   193 MIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVA--KVT------K 234  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   ++++ak+++Da YD+llkEM+fe+R+s++d++++++ElA++Ea++L++LE
  gi|2464770   235 DEQDAKPPPDA-YDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLE 283  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   +eRl+RM++++E ed+E+      Sv+k+k+rS+dDLdD           
  gi|2464770   284 NERLRRMRADGE-EDEEA------SVAKPKHRSADDLDD----------- 315  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+++          ++EddE+dd++a+d+d+    n+Gt+l++kKeavLk
  gi|2464770   316 GYFL----------AGEDDEGDDTLAYDLDG----NLGTHLNGKKEAVLK 351  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   +dEneDDd      DkeGee++EeD+dEESD+E+d+l+dLKe+e++++++
  gi|2464770   352 GDENEDDD------DKEGEEEEEEDSDEESDSEVDNLSDLKESESESEPE 395  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ea+kas k+KA  KKsadTiPASLd+sipFti++Pkt+e+++eLl+k+++
  gi|2464770   396 EAPKAS-KKKA--KKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHAT 442  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   ++k++I+eRIik++hpKL+++N +e++vK++++LLq++KDLfED+seQdi
  gi|2464770   443 AQKAIIIERIIKCNHPKLEGVN-RENVVKLYSFLLQYLKDLFEDASEQDI 491  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +++  fqLL+kL+++L+el+q++Pe+    +s++llevike++ee++kn 
  gi|2464770   492 REH--FQLLSKLMPYLYELTQLNPER----MSNTLLEVIKEKYEEFRKN- 534  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++yPSl++Lv+FkLv++l+sTSDfrH+VvTP+++++++vLsrs+v++++
  gi|2464770   535 HKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQ 584  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +I++GlfLv++VL+f+s+SkR+vP+V+++lq+i++ +++pKRDVe+l+it
  gi|2464770   585 EISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVH-MSIPKRDVEQLEIT 633  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Ferd  ++l+k   l++l+a++est+lepq+L+++DLVtqtit++f+
  gi|2464770   634 P-PFERD--GPLSK---LLALPANTESTKLEPQQLQPTDLVTQTITPDFK 677  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   v+al++SlLliKE+l+LvEe+v+++y++q       P+laLLsr++l es
  gi|2464770   678 VRALDTSLLLIKEALQLVEEHVGACYLAQ-------PFLALLSRLPL-ES 719  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   +pe+ ++++++da+el+eKl++   +++KPLA++e+KP+a+rlleP+FE+
  gi|2464770   720 YPEH-VHQHHKDATELAEKLAA---QKMKPLAPAEKKPKALRLLEPRFEA 765  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   +yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D++Fv++l
  gi|2464770   766 VYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTSFVQML 810  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   Rlk+++++d+erhEK+k+i++e+++q+g+l   
  gi|2464770   811 RLKQTLQSDKERHEKVKRIYQEASVQQGEL    840  

gi|19113534|ref|NP_596742.1|: domain 1 of 1, from 36 to 827: score 1741.6, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++edr++K   v+kiq++fN+Fd++++krKFd++Gr   +vKg+eGk
  gi|1911353    36    SHEDRQAK---VQKIQSDFNLFDRQFTKRKFDVGGR---RVKGTEGK 76   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR+++ee+R+rT++ae+kk+n+sga+iD+R+GE+n+hLs    +EeK
  gi|1911353    77 PGVSRGVGEELRRRTIGAELKKRNRSGAIIDRRFGENNPHLS----VEEK 122  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRfsRE+  Q+r SKre+ynl+  +EDv+++G+r++s    D+Ds+ee
  gi|1911353   123 MLERFSREQ--QRR-SKRELYNLD--AEDVLTHGNRPLS----DIDSFEE 163  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +g++L++++EL+de+  ++++++++Fe++DAe+e+e++GA+KsK+EVm+E
  gi|1911353   164 PGFGLDEGEELNDEV--VRRMHFGGFEDSDAENEKEGEGAHKSKREVMSE 211  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   iIaKSK+yKaEr++eKe++eD+++kLDe+++dL+s+l+++k++sRKsGiK
  gi|1911353   212 IIAKSKHYKAERQAEKERYEDEREKLDEQMEDLQSFLSDYKKASRKSGIK 261  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   ++r++++d+Da+YD++++EMvf+kRA+P++RTKTeEElAq+Ea++LreLE
  gi|1911353   262 TQRPIISDGDARYDSFVREMVFDKRAHPTERTKTEEELAQIEADRLRELE 311  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++R++RMe+++E++++E+             +S++D++++++V      f
  gi|1911353   312 DQRISRMEHYQEDSASEA-------------GSIEDEQATDNV------F 342  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+++l++     +NeE++++++eeae+s+D++svn+             
  gi|1911353   343 GFGKGLEQ-----ENEEEWNGINEEAEESEDEESVNS------------- 374  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ ++DdE++++EE                qpl+g
  gi|1911353   375 --------------DTS-FVDDEQLKVEE----------------QPLVG 393  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   +aik++++eKA               s+++t++cP++h+e+++Llk+ld+
  gi|1911353   394 SAIKNEGSEKA---------------SLAYTYPCPTSHVEFVQLLKGLDY 428  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p++V+RI+++hh+KL+++N K++l++Fsv+LLqhI  L+  l++Q++
  gi|1911353   429 KDYPTVVSRIRTLHHVKLHPDN-KSRLENFSVILLQHI--LH--LTRQPM 473  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   ++   ++LLe+L+e+L++laq++P++l+is+++++++++k+la++y+++ 
  gi|1911353   474 IS---MELLEHLTEHLHSLAQQFPSALGISFISVVEGMRKRLAKSYVYP- 519  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   +ik+P+++dL+fF+L+g++F+TSD++H+Vv+P++l+mae+Ls+sp++Sl+
  gi|1911353   520 EIKFPEISDLLFFNLTGSIFPTSDKKHIVVSPVMLTMAESLSQSPADSLS 569  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   d++++l++++++Lkfqs+S+RyvPeV++a++q+L+ ll+p    +++si+
  gi|1911353   570 DVCKKLYIANLFLKFQSYSHRYVPEVITAVSQALY-LLYP----NFISIV 614  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P+tF+++  Dsl++   ++nlfa+++++l+epqrLsl++      +ee+p
  gi|1911353   615 PGTFALP--DSLKE---KQNLFAIQDISLDEPQRLSLYE------LEELP 653  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   +++l+sS+L+i  +l+L+E++++iy+k+qAFiEIf+PI+++L++yslk++
  gi|1911353   654 TGLLQSSILFI--TLNLIEMAIDIYFKEQAFIEIFVPIMDMLQLYSLKKE 701  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   l++kRl+ekll+++++v++++e+ak++rKPLAlq+H+P++I++++PKFEE
  gi|1911353   702 LLSKRLSEKLLSTLQAVSDSIESAKANRKPLALQSHRPLGITSQVPKFEE 751  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   +y    s+dksS+D+D+eR++lnKL+a+++++kKGAiR+lRKDa+F+ar+
  gi|1911353   752 GY----SLDKSSHDIDPERAQLNKLRAQHRDAKKGAIRTLRKDARFIARE 797  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++E++akdq+++EKm+k++n+lq++++A+   
  gi|1911353   798 RRQEQRAKDQAYNEKMRKLENRLQHFDPAV    827  

gi|195570117|ref|XP_002103055.1|: domain 1 of 1, from 27 to 839: score 1670.2, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K         ++NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|1955701    27    NSTAQSSK---------RGNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++Tl+++f++k+K+++f+D+RiG   khLsGDqL+E++
  gi|1955701    62 PGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIG---KHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++Er    +    +a+++n  l+D+e++++rg++     l+++e+
  gi|1955701   109 MNARYLAER--CPKCPQPKAEKFN--LNDDELLTHRGQT-----LEEIEQ 149  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +++e+sdd+EL+deaLD+df+a+++F++e+++a+++q+        +++E
  gi|1955701   150 YRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQA--------AIDE 191  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I+++K++K+E+aKeK+ev Dl++kLD+N+k+Ll+l+   k t      K
  gi|1955701   192 MIVEQKRRKNEIAKEKDEVFDLTEKLDANYKLLLPLVN--KAT------K 233  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   ++++ak+++Da YD+llkEM+fe+R+s++d++++++ElA++Ea++L++LE
  gi|1955701   234 DEQDAKPPPDA-YDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLE 282  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   +eRl+RM++++E e++E+      S++k+k+rS+dDLdD           
  gi|1955701   283 NERLRRMRADGE-EEEEA------SIAKPKHRSADDLDD----------- 314  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+++          ++E dE+dd++a+d+d+    n+Gt+l++kKea  k
  gi|1955701   315 GYFL----------AGEGDEGDDTLAYDLDG----NLGTHLNGKKEAEAK 350  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   + EneDDd      D+eGee++EeD+dEESD+E+d+l+dLKe+e++++++
  gi|1955701   351 GNENEDDD------DEEGEEEEEEDSDEESDSEVDNLSDLKESESESEPE 394  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ea+kas k+KA  KKsadTiPASLd+sipFti++Pkt+e ++eLl+k+++
  gi|1955701   395 EAPKAS-KKKA--KKSADTIPASLDTSIPFTIKMPKTYENFTELLSKHAT 441  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   ++k++I+eRIik++hpKL+++N +e++vK++++LLq++KDLfED+seQdi
  gi|1955701   442 AQKATIIERIIKCNHPKLEGVN-RENVVKLYSFLLQYLKDLFEDASEQDI 490  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +++  fqLL+kL+++L+el+q++Pe+    +s++ll+vike++ e++kn 
  gi|1955701   491 REH--FQLLSKLMPHLYELTQLNPER----MSNTLLDVIKEKYGEFRKN- 533  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h+ yPSl++Lv+FkLv++l+sTSDfrH+VvTP++++m++vLsrs+v++++
  gi|1955701   534 HKLYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFMQHVLSRSRVRTRQ 583  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +I++GlfLv++VL+f+s+SkR+vP+++++lq+i++ +++pKRDVe+l+it
  gi|1955701   584 EISMGLFLVTVVLEFVSQSKRLVPAIFNFLQGIVH-MSIPKRDVEQLEIT 632  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Ferd  ++l+k   l++l+a++est lep +L++aDLVtqtit++f+
  gi|1955701   633 P-PFERD--GPLSK---LLALPAKTESTNLEPEKLQPADLVTQTITPDFK 676  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   v+al++SlLliKE+l+LvEe+v+++y++q       P+l LLsr++l  s
  gi|1955701   677 VRALDTSLLLIKEALQLVEEHVGACYLAQ-------PFLRLLSRLPL-DS 718  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   +pe+ ++++++ a+el+eKl++   +++KPLA+ e+KP+a+rlleP+FE+
  gi|1955701   719 YPEH-VHQHHKEATELAEKLAA---QKMKPLAPSEKKPKALRLLEPRFEA 764  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   +yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D+ Fv++l
  gi|1955701   765 VYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTAFVQTL 809  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   Rlk+++++d+erhEK+k+i++e+++q+g+l   
  gi|1955701   810 RLKQTLQSDKERHEKVKRIYQEASVQQGEL    839  

gi|194900416|ref|XP_001979753.1|: domain 1 of 1, from 27 to 839: score 1669.7, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K         ++NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|1949004    27    NSTAQSSK---------RGNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++Tl+++f++k+K+++f+D+RiG   khLsGDqL+E++
  gi|1949004    62 PGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIG---KHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r S+++a+++n  l+D+e++++rg++     l+++e+
  gi|1949004   109 MNARYLAEKMSQVR-SNQKAEKFN--LNDDELLTHRGQT-----LEEIEQ 150  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +++e+sdd+EL+deaLD+df+a+++F++e+++a+++q+        +++E
  gi|1949004   151 YRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQA--------AIDE 192  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I+++K++K+E+aKeK+ev+Dl++kLD+N+k+Ll+l+a  k t      K
  gi|1949004   193 MIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVA--KAT------K 234  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   ++++ak+++Da YD+llkEM+fe+R+s++d++++++ElA++Ea++L++LE
  gi|1949004   235 DEQDAKPPPDA-YDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLE 283  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   +eRl+RM++++E ed+E+      S++k+k+rS+dDLdD           
  gi|1949004   284 NERLRRMRADGE-EDEEA------SIAKPKHRSADDLDD----------- 315  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+++          ++EddE+dd++a+d+d+    n+Gt+l++kKe   k
  gi|1949004   316 GYFL----------AGEDDEGDDTLAYDLDG----NLGTHLNGKKEPKAK 351  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   + EneDD        +eG e++ eD+dEESD+E+d+l+dLKe+e++++ +
  gi|1949004   352 ENENEDDG-------EEGDEEEDEDSDEESDSEIDNLSDLKESESESEQE 394  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ea+kas k KA  KKsa TiPASLd+sipFti++Pkt+e++++Ll+k+++
  gi|1949004   395 EAPKAS-KMKA--KKSANTIPASLDTSIPFTIKMPKTYEDFTQLLSKHAT 441  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                    +k++I+eRIik++hpKL+++N +e++vK++++LLq++KDLfED+ eQdi
  gi|1949004   442 VQKAIIIERIIKCNHPKLEGVN-RENVVKLYSFLLQYLKDLFEDANEQDI 490  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +++  fqLL+kL+++L+el+q++Pe+    +s++llevike++ e++kn 
  gi|1949004   491 REH--FQLLSKLMPHLYELTQLNPER----MSNTLLEVIKEKYGEFRKN- 533  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++y Sl++Lv+FkLv++l+sTSDfrH+VvTP++++m++ Lsrs+v++++
  gi|1949004   534 HKMYASLETLVYFKLVANLYSTSDFRHPVVTPCFIFMQHILSRSRVRTRQ 583  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +I++GlfLv++VL+f+s+SkR+vP+V+++lq+i++ +++pKRDVe+l+it
  gi|1949004   584 EISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVH-MSIPKRDVEQLEIT 632  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Ferd  ++l+k   l++l+a++e t+lepq+L++ DLVtqtit++f+
  gi|1949004   633 P-PFERD--GPLSK---LLALPANTECTKLEPQQLQPVDLVTQTITPDFK 676  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   v+al++SlLliKE+l+LvEe+v+++y++q       P+l LLsr++l +s
  gi|1949004   677 VRALDTSLLLIKEALQLVEEHVGACYLAQ-------PFLRLLSRLPL-KS 718  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   +p + ++ +++ a+el+eKl++   +++KPLA++ +KP+a+rlleP+FE+
  gi|1949004   719 YPDH-VHLHHKEATELAEKLAA---QKMKPLAPAAKKPKALRLLEPRFEA 764  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   +yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D+ Fv+ l
  gi|1949004   765 VYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTAFVQEL 809  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +lk+++++d+erhEK+k+i++e+++q+g+l   
  gi|1949004   810 KLKQTLQSDKERHEKVKRIYQEASVQQGEL    839  

gi|6320053|ref|NP_010133.1|: domain 1 of 1, from 37 to 795: score 1625.6, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+dreeKKKA+a+i++efNPF++k+a++K++++++sKt++++++Gk
  gi|6320053    37    KEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGK 83   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rkr++ea++++knK+g++iDkR+GEr+k+L+    eEeK
  gi|6320053    84 PGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLT----EEEK 129  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+REr  Q++ SKr+a+++n  lED+e+dGd++g       D+l++
  gi|6320053   130 MLERFTRER--QSQ-SKRNANLFN--LEDDEDDGDMFG-------DGLTH 167  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   lg++Ls++dELa+++  +dfla+krF+e+DAe++++qr  kK+K+EVm+E
  gi|6320053   168 LGQSLSLEDELANDE--EDFLASKRFNEDDAELQQPQR--KKTKAEVMKE 213  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +IaKSK+yK+Er+K+++++eD+id+LD+Nf+d++s+l+m++++      K
  gi|6320053   214 VIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPK------K 257  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p+e+k+d+D+eYD+++kE++++kRA+PsdRTKTeEE++++++ek+reLE
  gi|6320053   258 NPMEPKTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELE 307  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++Rl+RM++++Ele+gEe             r+v+DLdD           
  gi|6320053   308 QQRLDRMNGMIELEEGEE-------------RGVEDLDD----------- 333  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+e          NeEd+Edd+++++dsdD                   
  gi|6320053   334 GFWE----------NEEDYEDDNDGIADSDD------------------- 354  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ +eD+++De+++                q+lk+
  gi|6320053   355 --------------DIK-FEDQGRDEGFS----------------QILKK 373  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ++i++s                           cP+th++ll+++kkldl
  gi|6320053   374 KNISIS---------------------------CPRTHDALLDQVKKLDL 396  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p+IV++Iika++pKL+e+N Kekl+KF++vLL+hI  +f  ls+Q++
  gi|6320053   397 DDHPKIVKNIIKAYQPKLAEGN-KEKLGKFTAVLLRHI--IF--LSNQNY 441  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +kn  +q+++++++aLi+++++l+ek++++lsee++++i+e++++ykkn 
  gi|6320053   442 LKN--VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKN- 488  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++++S++dLvfF+++g+lFsTSD++HlV+TPal+lm+++L++++++Slk
  gi|6320053   489 HFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLK 538  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +Ia+G++Lv+iV+++q+iSkRy+PeVvy++q+iL+t++v+    ++++++
  gi|6320053   539 RIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVE----KENQEK 584  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL+Fe++RLDs+e+GLPld++f++k+st++++++Ls++D      te++p
  gi|6320053   585 PLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMD------TEAHP 628  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   vd+++s+lL++  +++L+++i++++++l+AF+EI+lPI++LLs+y++k+s
  gi|6320053   629 VDQCVSVLLNV--MESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYS 676  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   ++ek  ++++l++ve+++K+te     ++PLAlq+HKPv+I++++PK+EE
  gi|6320053   677 DFEK--PRNILNKVEKLTKFTE-----HIPLALQNHKPVSIPTHAPKYEE 719  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +Pdk+SyDpD++Rse+nK+ka+lK+E+K++++E+RKDakF+ar+
  gi|6320053   720 NF----NPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQ 765  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++Ek+++++++h+Km++ivn+++++egA+   
  gi|6320053   766 RIEEKNKESSDYHAKMAHIVNTINTEEGAE    795  

gi|195497392|ref|XP_002096079.1|: domain 1 of 1, from 27 to 839: score 1623.0, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K         ++NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|1954973    27    NSTAQSSK---------RGNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++Tl+++f++k+K+++f+D+RiG   khLsGDqL+E++
  gi|1954973    62 PGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIG---KHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r S+++a+++n  l+D+e++++rg++     l+++e+
  gi|1954973   109 MNARYLAEKMSQVR-SNQKAEKFN--LNDDELLTHRGQT-----LEEIEQ 150  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +++e+sdd+EL+deaLD+df+a+++F++e+++a+++q+        +++E
  gi|1954973   151 YRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQA--------AIDE 192  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I+++K++K+E+aKeK+ev+Dl++kLD+N+k Ll+l+a  k t      K
  gi|1954973   193 MIVEQKRRKNEIAKEKDEVYDLTEKLDANYKHLLPLVA--KAT------K 234  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +++++k+++Da YD+llkEM+fe+R+s++d++++++El ++Ea++L++LE
  gi|1954973   235 DEQDPKPPPDA-YDKLLKEMIFEPRGSVADKLINPDELVKQEAARLEKLE 283  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   +eRl+RM++++E ed+E+      S++k+k+rS+dDLdD           
  gi|1954973   284 NERLRRMRADGE-EDEEA------SIAKPKHRSADDLDD----------- 315  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+++          + EddE+dd++a+d+d+    n+Gt+l++kKe   +
  gi|1954973   316 GYFL----------AVEDDEGDDTLAYDLDG----NLGTHLNGKKELKAE 351  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   + EneD d       +eGee++ eD+d ESD+E+d+l+dLKe+ ++++ +
  gi|1954973   352 GNENEDND-------EEGEEEENEDSDQESDSEVDNLSDLKESDSESEQE 394  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ea+kas k+KA  KKs  TiPASLd+sipFti++Pkt+++++eLl+k+++
  gi|1954973   395 EAPKAS-KKKA--KKSENTIPASLDTSIPFTIKMPKTYDDFTELLSKHAT 441  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   ++k++I+eRIik++hpKL+++N + ++vK++++LLq++KD fED+ eQ i
  gi|1954973   442 AQKATIIERIIKCNHPKLEGVN-RDNVVKLYSFLLQYLKDSFEDANEQEI 490  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +++  fqLL+kL+++ +el+q++Pe+    +s++llevike+  e++kn 
  gi|1954973   491 REH--FQLLSKLMPHFYELTQLNPER----MSNTLLEVIKEKNGEFRKN- 533  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++y Sl++Lv+FkLv++l+sTSDfrH+VvTP++++m++vLsrs+v++++
  gi|1954973   534 HKMYASLETLVYFKLVANLYSTSDFRHPVVTPCFIFMQHVLSRSRVRTRQ 583  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +I++GlfLv+++L+f+s+SkR+vP+V+++lq+i++ +++pKRDVe+l+it
  gi|1954973   584 EISMGLFLVTVILEFVSQSKRLVPAVFNFLQGIVH-MSIPKRDVEQLEIT 632  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Ferd  ++l+k   l++l+a++e t+l+pq+L++ DLVtqtit++f+
  gi|1954973   633 P-PFERD--GPLSK---LLALPANQECTKLKPQQLQPSDLVTQTITPDFK 676  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   v+al++SlLliKE+l+LvEe+v+++y++        P+l LLsr++l es
  gi|1954973   677 VRALDTSLLLIKEALQLVEEHVGACYLAK-------PFLRLLSRLPL-ES 718  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   +pe+ ++ +++ a+elveKl++   +++K LA++ +KP+a+rlleP+FE 
  gi|1954973   719 YPEH-VHLHHKEATELVEKLAA---QKMKLLAPAAKKPKALRLLEPRFEP 764  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   +yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D+ Fv+ l
  gi|1954973   765 VYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTAFVQEL 809  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +lk+++++d+erhEK+k+i++e+++q+g+l   
  gi|1954973   810 KLKQTLKSDKERHEKVKRIYQEASVQQGEL    839  

gi|190405151|gb|EDV08418.1|: domain 1 of 1, from 37 to 795: score 1622.5, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+dreeKKKA+a+i++efNPF++k+a++K++++++sKt++++++Gk
  gi|1904051    37    KEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGK 83   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rkr++ea++++knK+g++iDkR+GEr+k+L+    eEeK
  gi|1904051    84 PGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLT----EEEK 129  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+REr  Q++ SKr+a+++n  lED+e+dGd++g       D+l++
  gi|1904051   130 MLERFTRER--QSQ-SKRNANLFN--LEDDEDDGDMFG-------DGLTH 167  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   lg++Ls++dELa+++  +dfla+krF+e+DAe++++qr  kK+K+EVm+E
  gi|1904051   168 LGQSLSLEDELANDE--EDFLASKRFNEDDAELQQPQR--KKTKAEVMKE 213  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +IaKSK+yK+Er+K+++++eD+id+LD+Nf+d++s+l+m++++      K
  gi|1904051   214 VIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPK------K 257  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p+e+k+d+D+eYD+++kE++++kRA+PsdRTKTeEE++++++ek+reLE
  gi|1904051   258 NPMEPKTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELE 307  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++Rl+RM++++Ele+gEe             r+v+DLdD           
  gi|1904051   308 QQRLDRMNGMIELEEGEE-------------RGVEDLDD----------- 333  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+e          NeEd+Edd+++++dsdD                   
  gi|1904051   334 GFWE----------NEEDYEDDNDGIADSDD------------------- 354  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ +eD+ +De+++                q+lk+
  gi|1904051   355 --------------DIK-FEDQDRDEGFS----------------QILKK 373  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ++i++s                           cP+th++ll+++kkldl
  gi|1904051   374 KNISIS---------------------------CPRTHDALLDQVKKLDL 396  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p+IV++Iika++pKL+e+N Kekl+KF++vLL+hI  +f  ls+Q++
  gi|1904051   397 DDHPKIVKNIIKAYQPKLAEGN-KEKLGKFTAVLLRHI--IF--LSNQNY 441  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +kn  +q+++++++aLi+++++l+ek++++lsee++++i+e++++ykkn 
  gi|1904051   442 LKN--VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKN- 488  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++++S++dLvfF+++g+lFsTSD++HlV+TPal+lm+++L++++++Slk
  gi|1904051   489 HFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLK 538  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +Ia+G++Lv+iV+++q+iSkRy+PeVvy++q+iL+t++v+    ++++++
  gi|1904051   539 RIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVE----KENQEK 584  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL+Fe++RLDs+e+GLPld++f++k+st++++++Ls++D      te++p
  gi|1904051   585 PLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMD------TEAHP 628  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   vd+++s+lL++  +++L+++i++++++l+AF+EI+lPI++LLs+y++k+s
  gi|1904051   629 VDQCVSVLLNV--MESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYS 676  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   ++ek  ++++l++ve+++K+te     ++PLAlq+HKPv+I++++PK+EE
  gi|1904051   677 DFEK--PRNILNKVEKLTKFTE-----HIPLALQNHKPVSIPTHAPKYEE 719  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +Pdk+SyDpD++Rse+nK+ka+lK+E+K++++E+RKDakF+ar+
  gi|1904051   720 NF----NPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQ 765  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++Ek+++++++h+Km++ivn+++++egA+   
  gi|1904051   766 RIEEKNKESSDYHAKMAHIVNTINTEEGAE    795  

gi|151941853|gb|EDN60209.1|: domain 1 of 1, from 37 to 795: score 1617.8, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+dreeKKKA+a+i++efNPF++k+a++K++++++sKt++++++Gk
  gi|1519418    37    KEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGK 83   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rkr++ea++++k K+g++iDkR+GEr+k+L+    eEeK
  gi|1519418    84 PGISKQIGEEQRKRAFEARKMMKSKRGGVIDKRFGERDKLLT----EEEK 129  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+REr  Q++ SKr+a+++n  lED+e+dGd++g       D+l++
  gi|1519418   130 MLERFTRER--QSQ-SKRNANLFN--LEDDEDDGDMFG-------DGLTH 167  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   lg++Ls++dELa+++  + fla+krF+e+DAe++++qr  kK+K+EVm+E
  gi|1519418   168 LGQSLSLEDELANDE--EEFLASKRFNEDDAELQQPQR--KKTKAEVMKE 213  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +IaKSK+yK+Er+K+++++eD+id+LD+Nf+d++s+l+m++++      K
  gi|1519418   214 VIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPK------K 257  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p+e+k+d+D+eYD+++kE++++kRA+PsdRTKTeEE++++++ek+reLE
  gi|1519418   258 NPMEPKTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELE 307  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++Rl+RM++++Ele+gEe             r+v+DLdD           
  gi|1519418   308 QQRLDRMNGMIELEEGEE-------------RGVEDLDD----------- 333  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+e          NeEd+Edd+++++dsdD                   
  gi|1519418   334 GFWE----------NEEDYEDDNDGIADSDD------------------- 354  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ +eD+++De+++                q+lk+
  gi|1519418   355 --------------DIK-FEDQGRDEGFS----------------QILKK 373  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ++i++s                           cP+th++ll+++kkldl
  gi|1519418   374 KNISIS---------------------------CPRTHDALLDQVKKLDL 396  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p+IV++Iika++pKL+e+N Kekl+KF++vLL+hI  +f  ls+Q++
  gi|1519418   397 DDHPKIVKNIIKAYQPKLAEGN-KEKLGKFTAVLLRHI--IF--LSNQNY 441  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +kn  +q+++++++aLi+++++l+ek++++lsee++++i+e++++ykkn 
  gi|1519418   442 LKN--VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKN- 488  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++++S++dLvfF+++g+lFsTSD++HlV+TPal+lm+++L++++++Slk
  gi|1519418   489 HFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLK 538  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +Ia+G++Lv+iV+++q+iSkRy+PeVvy++q+iL+t++v+    ++++++
  gi|1519418   539 RIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVE----KENQEK 584  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL+Fe++RLDs+e+GLPld++f++k+st++++++Ls++D      te++p
  gi|1519418   585 PLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMD------TEAHP 628  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   vd+++s+lL++  +++L+++i++++++l+AF+EI+lPI++LLs+y++k+s
  gi|1519418   629 VDQCVSVLLNV--MESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYS 676  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   ++ek  ++++l++ve+++K+te     ++PLAlq+HKPv+I++++PK+EE
  gi|1519418   677 DFEK--PRNILNKVEKLTKFTE-----HIPLALQNHKPVSIPTHAPKYEE 719  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +Pdk+SyDpD++Rse+nK+ka+lK+E+K++++E+RKDakF+ar+
  gi|1519418   720 NF----NPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQ 765  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++Ek+++++++h+Km++ivn+++++egA+   
  gi|1519418   766 RIEEKNKESSDYHAKMAHIVNTINTEEGAE    795  

gi|256273589|gb|EEU08522.1|: domain 1 of 1, from 37 to 795: score 1612.5, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+dreeKKKA+a+i++efNPF++k+a++K++++++sKt++++++Gk
  gi|2562735    37    KEYDREEKKKAIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGK 83   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rkr++ea++++knK+g++iDkR+GEr+k+L+    eEeK
  gi|2562735    84 PGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLT----EEEK 129  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+REr  Q++ SKr+a+++n  lED+e+dGd++g       D+l++
  gi|2562735   130 MLERFTRER--QSQ-SKRNANLFN--LEDDEDDGDMFG-------DGLTH 167  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   lg++Ls++dELa+++  +dfla+krF+e+DAe++++qr  kK+K+EVm+E
  gi|2562735   168 LGQSLSLEDELANDE--EDFLASKRFNEDDAELQQPQR--KKTKAEVMKE 213  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +IaKSK+yK+Er+K+++++eD+id+LD+Nf+d++s+l+m++++      K
  gi|2562735   214 VIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPK------K 257  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p+e+k+d+D+eYD+++kE++++ RA+PsdRTKTeEE++++++ek+reLE
  gi|2562735   258 NPMEPKTDLDKEYDIKVKELQLDRRAAPSDRTKTEEEKNAEAEEKKRELE 307  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++Rl+RM++++Ele+gEe             r+v+DLdD           
  gi|2562735   308 QQRLDRMNGMIELEEGEE-------------RGVEDLDD----------- 333  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+e          NeEd+E d+++++dsdD                   
  gi|2562735   334 GFWE----------NEEDYENDNDGIADSDD------------------- 354  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ +eD+ +De+++                q+ k+
  gi|2562735   355 --------------DIK-FEDQDRDEGFS----------------QISKK 373  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ++i+++                           cP+th++ll+++kkldl
  gi|2562735   374 KNISIT---------------------------CPRTHDALLDQVKKLDL 396  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p+IV++Iika++pKL+e+N +ekl+KF++vLL+hI  +f  ls+Q++
  gi|2562735   397 DDHPKIVKNIIKAYQPKLAEGN-REKLGKFTAVLLRHI--IF--LSNQNY 441  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +kn  +q+++++++aLi+++++l+ek++++lsee++++i+e++++ykkn 
  gi|2562735   442 LKN--VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKN- 488  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++++S++dLvfF+++g+lFsTSD++HlV+TPal+lm+++L++++++Slk
  gi|2562735   489 HFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLK 538  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +Ia+G++Lv+iV+++q+iSkRy+PeVvy++q+iL+t++v+    ++++++
  gi|2562735   539 RIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVE----KENQEK 584  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL+Fe++RLDs+e+GLPld++f++k+st++++++Ls++D      te++p
  gi|2562735   585 PLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMD------TEAHP 628  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   vd+++s+lL++  +++L+++i++++++l+AF+EI+lPI++LLs+y++k+s
  gi|2562735   629 VDQCVSVLLNV--MESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYS 676  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   ++ek  ++++l++ve+++K+te     ++PLAlq+HKPv+I++++PK+EE
  gi|2562735   677 DFEK--PRNILNKVEKLTKFTE-----HIPLALQNHKPVSIPTHAPKYEE 719  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +Pdk+SyDpD++Rse+nK+ka+lK+E+K++++E+RKDakF+ar+
  gi|2562735   720 NF----NPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQ 765  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++Ek+++++++h+Km++ivn+++++egA+   
  gi|2562735   766 RIEEKNKESSDYHAKMAHIVNTINTEEGAE    795  

gi|207347062|gb|EDZ73369.1|: domain 1 of 1, from 3 to 757: score 1600.1, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                          ++ KK+ +a+i++efNPF++k+a++K++++++sKt++++++Gk
  gi|2073470     3    ----VKKKKRTIAEIREEFNPFEIKAARNKRRDGLPSKTADRIAVGK 45   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rkr++ea++++knK+g++iDkR+GEr+k+L+    eEeK
  gi|2073470    46 PGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRFGERDKLLT----EEEK 91   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+REr  Q++ SKr+a+++n  lED+e+dGd++g       D+l++
  gi|2073470    92 MLERFTRER--QSQ-SKRNANLFN--LEDDEDDGDMFG-------DGLTH 129  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   lg++Ls++dELa+++  +dfla+krF+e+DAe++++qr  kK+K+EVm+E
  gi|2073470   130 LGQSLSLEDELANDE--EDFLASKRFNEDDAELQQPQR--KKTKAEVMKE 175  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +IaKSK+yK+Er+K+++++eD+id+LD+Nf+d++s+l+m++++      K
  gi|2073470   176 VIAKSKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTQPK------K 219  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p+e+k+d+D+eYD+++kE++++kRA+PsdRTKTeEE++++++ek+reLE
  gi|2073470   220 NPMEPKTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAEAEEKKRELE 269  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                   ++Rl+RM++++Ele+gEe             r+v+DLdD           
  gi|2073470   270 QQRLDRMNGMIELEEGEE-------------RGVEDLDD----------- 295  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   Gf+e          NeEd+Edd+++++dsdD                   
  gi|2073470   296 GFWE----------NEEDYEDDNDGIADSDD------------------- 316  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                 D++ +eD+ +De+++                q+lk+
  gi|2073470   317 --------------DIK-FEDQDRDEGFS----------------QILKK 335  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   ++i++s                           cP+th++ll+++kkldl
  gi|2073470   336 KNISIS---------------------------CPRTHDALLDQVKKLDL 358  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   +D+p+IV++Iika++pKL+e+N Kekl+KF++vLL+hI  +f  ls+Q++
  gi|2073470   359 DDHPKIVKNIIKAYQPKLAEGN-KEKLGKFTAVLLRHI--IF--LSNQNY 403  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +kn  +q+++++++aLi+++++l+ek++++lsee++++i+e++++ykkn 
  gi|2073470   404 LKN--VQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKN- 450  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h++++S++dLvfF+++g+lFsTSD++HlV+TPal+lm+++L++++++Slk
  gi|2073470   451 HFDALSNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLK 500  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +Ia+G++Lv+iV+++q+iSkRy+PeVvy++q+iL+t++v+    ++++++
  gi|2073470   501 RIAFGAVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVE----KENQEK 546  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   PL+Fe++RLDs+e+GLPld++f++k+st++++++Ls++D      te++p
  gi|2073470   547 PLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTLSTMD------TEAHP 590  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                   vd+++s+lL++  +++L+++i++++++l+AF+EI+lPI++LLs+y++k+s
  gi|2073470   591 VDQCVSVLLNV--MESLDATISTVWKSLPAFNEIILPIQQLLSAYTSKYS 638  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                   ++ek  ++++l++ve+++K+te     ++PLAlq+HKPv+I++++PK+EE
  gi|2073470   639 DFEK--PRNILNKVEKLTKFTE-----HIPLALQNHKPVSIPTHAPKYEE 681  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                   n+    +Pdk+SyDpD++Rse+nK+ka+lK+E+K++++E+RKDakF+ar+
  gi|2073470   682 NF----NPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQ 727  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   R++Ek+++++++h+Km++ivn+++++egA+   
  gi|2073470   728 RIEEKNKESSDYHAKMAHIVNTINTEEGAE    757  

gi|194745272|ref|XP_001955112.1|: domain 1 of 1, from 27 to 844: score 1421.3, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++ d + K           NPFdv+v+k+KF ilGr   ++K+++G+
  gi|1947452    27    SSNDPSNK------RAGNQNPFDVHVNKEKFQILGR---ICKHDRGM 64   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++Tl+++f++k+K+++f+D+RiG   khLs DqL+E++
  gi|1947452    65 PGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIG---KHLSADQLTESV 111  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r   ++ +++n  l+D+e++++rg++     l+++e+
  gi|1947452   112 MNARYLAEKMSQVR-QSQKSEKFN--LNDDELLTHRGQT-----LEEIEQ 153  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +++e+sdd+EL+de LD+ f+ +++F+++++  +++q         ++eE
  gi|1947452   154 YRDERSDDEELDDERLDAEFTSAAHFGGDGDAPQDRQT--------AIEE 195  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I ++K++K+E+aKeK+ev+Dl++kLD+N+k+Ll+l+a  k t      K
  gi|1947452   196 MISEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVA--KAT------K 237  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +++eak+++Da YD+llkEM+fe+R+s++d+++++EElA++Eae+L++LE
  gi|1947452   238 DEQEAKPPPDA-YDKLLKEMIFEPRGSVTDKLINPEELAKQEAERLEKLE 286  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                    eRl+RM++++E ed+E+        +k+k+rS+dDLdD           
  gi|1947452   287 KERLRRMRADGE-EDEEA------EAAKPKHRSADDLDD----------- 318  

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   G+++          ++ d E dd++a+d+d+    n+Gt+l++k     +
  gi|1947452   319 GYFL----------AGGDEEADDTLAYDLDG----NLGTHLNGKHNGK-E 353  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                   +  neD +     ED+   e+  eD+dE SD+E+d+l+dLKe+ ++++ +
  gi|1947452   354 GADNEDEE---NAEDEG-DEEGDEDSDEDSDSEVDNLSDLKESDSESEAE 399  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   e +  s k+KA   Ks d     +d+sipFti++Pkt+e++++Ll+k++ 
  gi|1947452   400 ETPQPS-KKKA--TKSVDQSSTDVDTSIPFTIKMPKTYEDFTDLLSKHAA 446  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                    + ++IVeRIik++hpKL+++N +e++vK++++LLq+IKDLfED+seQdi
  gi|1947452   447 PQQATIVERIIKCNHPKLEGVN-RENVVKLYSFLLQYIKDLFEDASEQDI 495  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   + n  fqL++kL+++L+ l+q++Pe+    +s++llevike++ e++kn 
  gi|1947452   496 RGN--FQLFSKLMPHLYDLTQLNPER----MSNTLLEVIKEKYGEFRKN- 538  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h+ yP l++L++FkLv++l+sTSDfrH+VvTP++++m++ Lsr +v++++
  gi|1947452   539 HKTYPTLDTLIYFKLVANLYSTSDFRHPVVTPCFIFMQHILSRARVRTRQ 588  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   +I++GlfL ++VL+f+s+SkR +P+V ++lq+ ++ +++pKRDVe++ it
  gi|1947452   589 EISMGLFLTTVVLEFVSQSKRILPAVYNFLQGVVH-MSIPKRDVEQIAIT 637  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Fe+d  ++l+k   l++l   ke   le q L+ +DLVtqtit++f+
  gi|1947452   638 P-PFEKD--GPLSK---LLALSSGKETKNLEAQALQATDLVTQTITPDFK 681  

                   vdalrsSl.LliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslke
                   v+al + l+L + + l+LvEe+v+++y++        P+l LLsr++l  
  gi|1947452   682 VRALNTALqLTV-DSLQLVEEHVGVCYLAT-------PFLGLLSRLPL-D 722  

                   slpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFE
                    +pe+ ++ +++ a+elv  l     +++KPLA++e+KP+a+rlleP+FE
  gi|1947452   723 LYPEH-VHLNHKAATELVQRLGG---QKMKPLAPAERKPKALRLLEPRFE 768  

                   EnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvar
                    +yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D+ Fv+ 
  gi|1947452   769 TVYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTAFVQE 813  

                   lRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   l+lk+++ +d+er EK+k+i++e++ q+g+l   
  gi|1947452   814 LKLKQTLRSDKERQEKVKRIYQEASMQQGEL    844  

gi|195144178|ref|XP_002013073.1|: domain 1 of 1, from 27 to 842: score 1305.2, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      + +++++K         + NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|1951441    27    SATAQSAK---------RQNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGV R ka++kR +Tl+++f++k+K++ f+D+RiG    hLsGDqL+E++
  gi|1951441    62 PGVARSKALQKRTQTLGQQFAVKHKTNKFKDNRIG---RHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r   ++a ++n  l+D+e++++rg++     l+++e+
  gi|1951441   109 MNARYLAEKMSQVR-TSQKAQKFN--LNDDELLTHRGQT-----LEEIEQ 150  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAea..eeeqrGAkKsKkEVm
                   +++e+sdd+EL+deaLD+df+ +++F+++D e ++ ++q         ++
  gi|1951441   151 YRDERSDDEELDDEALDADFTSAAHFGGDDNETspHDRQV--------AI 192  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                   +E+Ia++K++K+E+ KeK ev+Dl++kLD+N+k+Ll+l+a  k t     
  gi|1951441   193 DEMIAEQKRRKNEIDKEKNEVYDLTEKLDANYKLLLPLVA--KAT----- 235  

                   iKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLre
                    K++ eak++ Da YD+llkEM+fe+R+s++d+++++ ElA++Eae+L++
  gi|1951441   236 -KDEEEAKPPADA-YDKLLKEMIFEPRGSVTDKLINPVELAKQEAERLEK 283  

                   LEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP
                   LE+eRl+RM++ +E ed  +        +++k+rS+dDLdD         
  gi|1951441   284 LENERLRRMRAEGE-EDPAA-------SAQPKHRSADDLDD--------- 316  

                   KfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqk...K
                     G++           ++ +d++dd++a+d+d+    n+Gt+l +k + K
  gi|1951441   317 --GYFV----------AGGEDDGDDTLAYDLDG----NLGTHLSGKapaK 350  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                   ea   +dE+ D d      D   ee+d eD+ E+   E ++++dL e+ea
  gi|1951441   351 EASGDEDEEADGD------DDG-EEEDSEDDSES---EAENYSDLDESEA 390  

                   qplkgeaikasvkeKANmKKsadTiPASL.drsipFtidcPktheelleL
                   +++ +ea       K   KK     PA  +d sipFti++Pk++e+++eL
  gi|1951441   391 ESETEEASAEPTQRKP--KKEKLKAPATTeDSSIPFTIKMPKSYEDFTEL 438  

                   lkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfED
                   l+ ++ ++ ++IVeRIik++ pKL ++N +e++vK++ +LLq++KDLfED
  gi|1951441   439 LSRHAVAQQATIVERIIKCNDPKLDGVN-RENVVKLYCFLLQYLKDLFED 487  

                   lseQdikknLNfqLLekLveaLielaqelPeklaislseellevikelae
                   +seQdi+ +  fqLL++L+++L+ l+q +Pe+    +s+ ll+vike+  
  gi|1951441   488 ASEQDIRQH--FQLLSRLMPHLYTLTQMNPER----MSSALLDVIKEKFG 531  

                   eykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrs
                     +kn  + yP l++Lv+FkLv++ +sTSDfrH+V TP   +m + Lsr 
  gi|1951441   532 DHRKN-SKTYPTLDTLVYFKLVSNVYSTSDFRHPVATPTYVFMEHILSRA 580  

                   pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDV
                   +v++++dIa+Glf v i L+f s+SkR++P V+++l++iL+   +pKRD 
  gi|1951441   581 RVRTRQDIAMGLFVVAIALEFGSQSKRFLPSVFNFLEGILY-IAIPKRDA 629  

                   ellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqt
                    +l +tP +F +d  ++++k   l++++a  es  le q+L+ aDLVt t
  gi|1951441   630 DELVVTP-PFDLD--GPFSK---LLAIPATAESKALEHQKLQAADLVTHT 673  

                   iteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsr
                   it +f+v+al++ l li+E+l+Lv e+ +++y+++       P+  LL r
  gi|1951441   674 ITLDFKVRALDTALCLIQEALQLVGEHTGACYLAS-------PFIPLLAR 716  

                   yslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrll
                   + l + +pe+ +++++  a +l+  l+e   +++KP Al+e+KP+a+r+l
  gi|1951441   717 LRL-KPYPEH-VHQHHREASQLAKQLAE---QKMKPVALAERKPKALRML 761  

                   ePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDa
                   eP+FE +yDDKR+P++s     ke++e++KL++k+KrEkKGAiRE+R+D+
  gi|1951441   762 EPRFETVYDDKRRPKMS-----KEKEERAKLLHKIKREKKGAIREIRRDT 806  

                   kFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    Fv+ l+lk+++++d+erhEK+k+i++e++ q+g+l   
  gi|1951441   807 AFVQELKLKQQLQSDKERHEKVKRIYQEASMQQGEL    842  

gi|125774125|ref|XP_001358321.1|: domain 1 of 1, from 27 to 842: score 1298.0, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      + +++++K         + NPFdv+v+k+KF+ilGr   ++K+++G+
  gi|1257741    27    SATAQSAK---------RQNPFDVHVNKEKFKILGR---ICKHDRGM 61   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGV R ka++kR +Tl+++f++k+K++ f+D+RiG    hLsGDqL+E++
  gi|1257741    62 PGVARSKALQKRTQTLGQQFAVKHKTNKFKDNRIG---RHLSGDQLTESV 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++R+++E+mSQ+r   ++a ++n  l+D+e++++rg++     l+++e+
  gi|1257741   109 MNARYLAEKMSQVR-TSQKAQKFN--LNDDELLTHRGQT-----LEEIEQ 150  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAea..eeeqrGAkKsKkEVm
                   +++e+sdd+EL+deaLD+df+ +++F+++D e ++ ++q         ++
  gi|1257741   151 YRDERSDDEELDDEALDADFTSAAHFGGDDNETspHDRQV--------AI 192  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                   +E+Ia++K++K+E+ KeK ev+Dl++kLD+N+k+Ll+l+a  k t     
  gi|1257741   193 DEMIAEQKRRKNEIDKEKNEVYDLTEKLDANYKLLLPLVA--KAT----- 235  

                   iKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLre
                    K+++eak++ D  YD+llkEM+fe+R+s++d+++++ ElA++Eae+L++
  gi|1257741   236 -KDEQEAKPPADG-YDKLLKEMIFEPRGSVTDKLINPVELAKQEAERLEK 283  

                   LEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP
                   LE+eRl+RM++ +E ed  +        +++k+rS+dDLdD         
  gi|1257741   284 LENERLRRMRAEGE-EDPAA-------SAQPKHRSADDLDD--------- 316  

                   KfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqk...K
                     G++           ++ +d++dd++a+d+d+    n+Gt+l++k + K
  gi|1257741   317 --GYFV----------AGGEDDGDDTLAYDLDG----NLGTHLNGKapaK 350  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                   e    +dE+ D d      D   ee++ eD+ E+   E ++++dL e+ea
  gi|1257741   351 ESSGDEDEEADGD------DDG-EEEESEDDSES---EAENYSDLDESEA 390  

                   qplkgeaikasvkeKANmKKsadTiPASL.drsipFtidcPktheelleL
                   +++ +ea      +K   KK     PA  +d sipFti++Pkt+e+++eL
  gi|1257741   391 ESETEEASAEPTQKKP--KKEKPKAPATTeDSSIPFTIKMPKTYEDFTEL 438  

                   lkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfED
                   l+ ++ ++ ++IVeRIik++ pKL ++N +e++vK++ +LLq++KDLfED
  gi|1257741   439 LSRHAVAQQATIVERIIKCNDPKLDGVN-RENVVKLYCFLLQYLKDLFED 487  

                   lseQdikknLNfqLLekLveaLielaqelPeklaislseellevikelae
                   +seQdi+++  fqLL++L+++L+ l+q +Pe+    +s+ ll+vike+  
  gi|1257741   488 ASEQDIREH--FQLLSRLMPHLYTLTQMNPER----MSSALLDVIKEKFG 531  

                   eykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrs
                     +kn  + yP l++L++FkLv++ +sTSDfrH+V TP   +m + Lsr 
  gi|1257741   532 DHRKN-SKTYPTLDTLIYFKLVSNVYSTSDFRHPVATPTYVFMEHILSRA 580  

                   pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDV
                   +v++++dIa+Glf v i L+f s+SkR++P V+++l++iL+   +pKRD 
  gi|1257741   581 RVRTRQDIAMGLFVVAIALEFGSQSKRFLPSVFNFLEGILY-IAIPKRDA 629  

                   ellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqt
                    +l +tP +F +   ++++k   l++++a  es  le q+L+ aDLVt t
  gi|1257741   630 DELVVTP-PFDLE--GPFSK---LLAIPATAESKALEQQKLQAADLVTHT 673  

                   iteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsr
                   it +f+v+al++ l li+E+l+Lv e+ +++y+++AFi        LL r
  gi|1257741   674 ITLDFKVRALDTALCLIQEALQLVGEHTGACYLASAFI-------PLLAR 716  

                   yslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrll
                   + l + +pe+ +++++  a +l+  l+e   +++KP Al+e+KP+a+r+l
  gi|1257741   717 LRL-KPYPEH-VHQHHREASQLAKQLAE---QKMKPVALAERKPKALRML 761  

                   ePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDa
                   eP+FE +yDDKR+P++s     ke++e++KL++k+KrEkKGAiRE+R+D+
  gi|1257741   762 EPRFETVYDDKRRPKMS-----KEKEERAKLLHKIKREKKGAIREIRRDT 806  

                   kFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    Fv+ l+lk+++++d+erhEK+k+i++e++ q+g+l   
  gi|1257741   807 AFVQELKLKQQLQSDKERHEKVKRIYQEASMQQGEL    842  

gi|195055991|ref|XP_001994896.1|: domain 1 of 1, from 9 to 842: score 1296.5, E = 0
                   *->keedreeKK.........KAvakiqkefNPFdvkvakrKFdilGrsK
                      + +++  KK+++++++ + A+a + k+ NPFdv+v+k+KF+ilGr  
  gi|1950559     9    SADAVYTKKstkssnpfdNAIAQTAKRLNPFDVHVNKEKFKILGR-- 53   

                   tkvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhL
                    ++K+++G+PGVSRaka+ekR++T+++++++knK++ f+DkRiG   khL
  gi|1950559    54 -ICKHDRGMPGVSRAKALEKRAQTIGKQYAVKNKTNTFVDKRIG---KHL 99   

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   sGDqL+E++M++R+++E++SQ+r +  +a+++n  l+D+e++++rg++  
  gi|1950559   100 SGDQLTESVMNARYLAEKLSQVR-ASNKAEKFN--LNDDELLTHRGQT-- 144  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                      l+++e++++e+sdd+ L+de LD+ f+ +++F+++++  +++q    
  gi|1950559   145 ---LEEIEQYRDERSDDEDLDDEGLDAEFTSAAHFGGDGDAPQDRQT--- 188  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                        ++eE+I ++K++K+E+aK K+ev Dl++kLD+N+k Llsl+a  +
  gi|1950559   189 -----AIEEMITEQKRRKNEIAKDKDEVNDLTEKLDANYKQLLSLVA--Q 231  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                    t      K+++  k++ Da YD+llkEM+fe+R+s++d+++ +EElA++
  gi|1950559   232 AT------KDEQHEKPPADA-YDKLLKEMIFEPRGSVTDKLIKPEELAKQ 274  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   Ea++L++LE+eRl+RM+ ++E e +              +rS+dDLdD  
  gi|1950559   275 EAARLEKLENERLRRMKFDGE-EQETN--------VHIPHRSADDLDD-- 313  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                            G++             E+ E+dd +a+d+d+    n+Gt+l
  gi|1950559   314 ---------GYFV---------AGNEEEEGDDVLAYDLDG----NLGTHL 341  

                   kqkKeavLkddEneDDdLGAE.LEDkeGeeDdEeDedEESDaEldvlkdL
                     kKe      E++   L  E+ ED+   +DdE  e EESD+Eld+l+dL
  gi|1950559   342 SSKKET-----EQSNTKLDEEgNEDED--DDDEDEEEEESDSELDNLSDL 384  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke+ ++++ +e    +   K    K   T  AS+d+sipFti++Pkt+e+
  gi|1950559   385 KESDSESEAEETAQQT-QVKSKRQKQQQT-TASMDTSIPFTIKMPKTYED 432  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   + eLl+k + ++ +++VeRIik++hpKL+++N +e++vK++++LLq+IKD
  gi|1950559   433 FGELLSKYSPAQQATVVERIIKCNHPKLEGVN-RENVVKLYAFLLQFIKD 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                   +fED+seQdi+++  fqLL  L+++ + l+q++Pe+    +s++ll+vik
  gi|1950559   482 MFEDASEQDILSH--FQLLAQLMPHMYDLTQLNPER----MSNTLLDVIK 525  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+++ey+kn h+ yPSl++L++FkLv++l+sTSDfrH+V TP  ++m++ 
  gi|1950559   526 EKYAEYRKN-HKVYPSLDTLIYFKLVSNLYSTSDFRHPVATPTYIFMQHI 574  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   Lsr ++++++dIa+GlfLv+i  +f s SkR++P+V+++l +iL+ + +p
  gi|1950559   575 LSRARIRTRQDIAMGLFLVNIAMEFGSRSKRLLPAVFNFLLGILH-MVIP 623  

                   KRDVe.llsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                   KR  e++  i+P +Ferd  ++++k   l++++a kes  lepq+L+ aD
  gi|1950559   624 KRQTEdQYDIVP-PFERD--GPFSK---LLAIPATKESQALEPQQLQAAD 667  

                   LVtqtiteefpvdalrsSlLliKE.vleLvEeiveiyyklqAFiEIflPI
                   LVt t t +f+v+a ++ l liK   +eLv e+++++y++        P+
  gi|1950559   668 LVTHTFTLDFKVRAVDATLRLIKNiFEELVGEHIGACYLAN-------PF 710  

                   laLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKP
                   l LL r++l + +pe+ ++e++  a  ++    +   +++K LA++ +KP
  gi|1950559   711 LPLLERLPL-KHYPEH-VQEHHAAAKSALQQVSA---QKMKRLAPADKKP 755  

                   vaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiR
                   +a+rlleP+FE +yDDKR+P++s     k ++e++KL++k+KrEkKGAiR
  gi|1950559   756 KALRLLEPRFEVVYDDKRRPKMS-----KQKEERAKLLHKIKREKKGAIR 800  

                   ElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   E+R+D+ Fv+ l+lk++ ++d+erhEK+k+i++e++ q+g+l   
  gi|1950559   801 EIRRDTAFVQDLKLKQQIQSDKERHEKVKRIYQEASMQQGEL    842  

gi|195970395|gb|ACG60683.1|: domain 1 of 1, from 21 to 863: score 1272.0, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +++++++K    ak +k +NPF+++ ++rKFd+lG+   k+Kgee+ 
  gi|1959703    21    GPDAVAMK----AKAKKADNPFESIWSRRKFDVLGK---KRKGEERR 60   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   +G SR +a++kRk+Tl +e+++++Ks++f DkRiGE + +L+    e++K
  gi|1959703    61 VGLSRSRAVDKRKNTLLKEYEQSLKSSVFMDKRIGEHDNELG----EFDK 106  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKDDlDsle
                   +++R++R r  Ql+ +K+++ynl+DG+E v+ dG++g s+S +DD+Ds+ 
  gi|1959703   107 GVIRSQRAR--QLK-AKKSMYNLSDGEEHVYGDGALGESsSARDDFDSVH 153  

                   elgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVme
                   +++e+L+dd    d+              +     + +r   KsKkEVm+
  gi|1959703   154 LSDEDLQDDGDREDAG-------------SNSMFIKFRR---KSKKEVMD 187  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   EiI+KSKl+K+E+aK Kee+e+l d L +   +L ++ am +lt      
  gi|1959703   188 EIIMKSKLGKMEKAKHKEEKEKLLDDLNKELMSLENSDAMKSLT------ 231  

                   KkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreL
                    + +  k  + ++Y     ++  + R++P+dRTKT+EE+Aq+E+ekL+eL
  gi|1959703   232 -QDFTVKDEPHDKYAMYMDDLASDRRGRPTDRTKTPEEIAQEEREKLEEL 280  

                   EeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPK
                   E+ R+kRM+et  l+d++eE GGEES k+l+v+S+dDL+Dsfs + ++PK
  gi|1959703   281 EDKRKKRMQETDDLSDEDEETGGEESSKRLRVISGDDLGDSFSADAEQPK 330  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDdd..svndGtdlkqkKea
                    G+i+++le       e ddEd  +e e++dDdd++ ++dG+d+kq+K++
  gi|1959703   331 KGWIDEVLE------REGDDEDSESEGEEEDDDDeeEESDGGDEKQRKGH 374  

                   vLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp
                    Lkd+E++DD+L AELE   G +D+Ee e E       v+k+ K d ++p
  gi|1959703   375 PLKDWEQSDDELEAELE---GDDDEEEEEAEP-----IVHKKSKKDSSAP 416  

                   lkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkk
                    kg++ +++vk  +NmKK ++T     + +ip+ i  Pk++eel++L+++
  gi|1959703   417 TKGKGSSGTVKQSTNMKKLSST-----QHDIPYVIHAPKSFEELIALVED 461  

                   ldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlse
                    +++D+ +IV+RI++  ++KL++eNRK+++v F+ +LLq+        ++
  gi|1959703   462 RSNADVVTIVNRIRTTDSIKLAAENRKKMQV-FYGILLQYF-------AV 503  

                   QdikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeyk
                   ++ kk+LN++LL++Lv++Lie++ e+P+++ai+++++ll+++ +++e++k
  gi|1959703   504 LANKKPLNIELLNMLVKPLIEMSGEIPYFAAICARQRLLKTRAQFCEAIK 553  

                   knEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvs
                   ++E++++PSlk+L++++L++ +F++SD rH+V+TP++llm+e+L+r+p+s
  gi|1959703   554 NPEDGCWPSLKTLFLLRLWSMIFPCSDYRHAVMTPSILLMCEYLMRCPIS 603  

                   SlkdIaiGlfLvsiV.LkfqsiSkRyvPeVvya........lqqiLftll
                   S++d+aiG+fL+siV Lkf      +++ +  a ++++ ++++   f ++
  gi|1959703   604 SGRDVAIGSFLCSIVlLKFCPEAILFIRTLLMAasdknlppFEESEF-YH 652  

                   vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsla
                   ++    el+ +tP ++++d             +++v ++++l ++  + a
  gi|1959703   653 FM----ELKTLTPFLCIQD------------DVKEVVPLNFLQIMDQP-A 685  

                   DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPI
                   D      +++f++d +r+S+L++  v+e++ ++vei+++l++F+EIf+PI
  gi|1959703   686 D------SPYFSSDEFRASILSS--VVETLRGFVEINGGLSSFPEIFMPI 727  

                   laLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKP
                   +aLL++ +++e++p++ l ekl da++l+eK+te+++k+rKPLA+++ KP
  gi|1959703   728 SALLHQVGNQEKIPQT-LREKLVDAAQLIEKKTEEHHKQRKPLAMRKQKP 776  

                   vaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiR
                   vaIr+++PKFEEn+      + + yDpDk+Rs+++KLk+kl  E+KG +R
  gi|1959703   777 VAIRMVNPKFEENF----AKGRD-YDPDKYRSDMKKLKKKLNEERKGVVR 821  

                   ElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ElRKD++F++ +++kEka ++qer+EK++k  ++lqeqe+A+   
  gi|1959703   822 ELRKDSYFMSDVKAKEKAVQEQERAEKHGKNLAFLQEQEHAF    863  

gi|195453284|ref|XP_002073720.1|: domain 1 of 1, from 30 to 853: score 1270.7, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      + e  + K           N Fd++v+k+KF ilGr   ++K+++G+
  gi|1954532    30    SKEQTATK---------GQNAFDIHVNKEKFQILGR---ICKHDRGM 64   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka++kR++T+++++++knK++ f+D+RiG   khLsGDqL+E++
  gi|1954532    65 PGVSRAKALQKRAQTIGKQYAVKNKTNKFVDRRIG---KHLSGDQLTESV 111  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M++Rf++E+mSQ+r +  +a+  n  l+D+e++++rg++     l+++e+
  gi|1954532   112 MNARFLAEKMSQVR-ASNKAERYN--LNDDELLTHRGQT-----LEEIEQ 153  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAe.aeeeqrGAkKsKkEVme
                   +++e+sdd+EL+de LD+df+ ++ F++ D e+a+++q         +++
  gi|1954532   154 YRDERSDDEELDDEGLDADFTSAANFGGGDEEtAQDRQT--------AID 195  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                    +I ++K++K+E+aKeK+ev+Dl++kLD+N+k+Ll+l+a  k t      
  gi|1954532   196 KMILEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVA--KAT------ 237  

                   KkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreL
                   K+ + +k+++Da YD+llkEM+fe+R+s+sd++++ EElA++Eae+L++ 
  gi|1954532   238 KDDQAPKPPPDA-YDKLLKEMIFEPRGSVSDKLINVEELAKQEAERLEKM 286  

                   EeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPK
                   E+eRl+RM++++E  + ++        +++k+rS+dDLdD          
  gi|1954532   287 ENERLRRMKADGEEDEKDA-------KARPKHRSADDLDD---------- 319  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavL
                    G++           ++ ddE dd++a+d+d+    n+Gt+l++k   v 
  gi|1954532   320 -GYFV----------AGDDDEPDDTLAYDLDG----NLGTHLNGKTNKVQ 354  

                   k....ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                    ++++ddE++DD+     ED e ee++EeD+d    +E+d+l+dLKe+ +
  gi|1954532   355 SdkpgDDEEDDDE-----EDGEEEEEEEEDSDDD--SEVDNLSDLKESDS 397  

                   qplkgeaikasvkeKANmKKsadTiPASL.drsipFtidcPktheelleL
                   ++  + a+  s   K   KKs+  i   ++d+ ipFt ++Pkt+e++++L
  gi|1954532   398 ESDAEAAPEQS-ATKSPKKKSSTSIESKIeDTTIPFTLKMPKTYEDFTQL 446  

                   lkkldl.eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfE
                         + + ++IVeR ik+hhpKL+++N +e +vK+++ LLq+IKD fE
  gi|1954532   447 FDQYPQpGQQATIVERLIKCHHPKLEGVN-REHVVKLYSYLLQYIKDRFE 495  

                   DlseQdikknLNfqLLekLveaLielaqelPeklaislseellevikela
                   D+seQdi kn  f L + L+++L+ l+q++P +    +s++llevike++
  gi|1954532   496 DASEQDIGKN--FKLISGLMPHLYDLTQLNPLR----MSSTLLEVIKEKY 539  

                   eeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsr
                   ++y+kn h+ yP l++ ++FkLv++++sTSDfrH+  TP  +++++ Lsr
  gi|1954532   540 AAYRKN-HKIYPTLDTFIYFKLVANIYSTSDFRHPLATPTYIFIQHILSR 588  

                   spvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRD
                    +v++++dI +GlfLv+i L+f s SkR++P V+++lq+ ++ +++pKRD
  gi|1954532   589 ARVRTRQDIGMGLFLVTIALEFGSLSKRLLPCVFNFLQGVVH-MSIPKRD 637  

                   VellsitPLtFerdRLDslekGLPldnl..favkestllepqrLslaDLV
                   Ve+ +i P +Fe +  ++l+k   l+++++ + kest l  q+L+  DLV
  gi|1954532   638 VEQVEIPP-PFETI--GPLSK---LLAIssSTAKESTSLDGQKLQAEDLV 681  

                   tqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaL
                   tqt+t +f v+al++Sl li+E+ eLv+e+ +++y++        P+l L
  gi|1954532   682 TQTVTLDFRVRALDTSLCLIRETMELVAEHPGACYLAT-------PFLPL 724  

                   LsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaI
                   L r++l + +p + ++++++ a el++ l+e   ++ K LA++e+KP+a+
  gi|1954532   725 LNRLPL-KLYPVH-VHQHHKEAKELLSQLAE---QKQKRLAPAERKPKAL 769  

                   rllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElR
                   rlleP+FE++yDDKR+P++s     k+++e++KL +k++rEkKGAiRE+R
  gi|1954532   770 RLLEPRFEAVYDDKRRPKMS-----KAKEERAKLVHKIRREKKGAIREIR 814  

                   KDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +D+ Fv+ l+lk+ +++d+erhEK+k+i++e++ q+g+l   
  gi|1954532   815 RDTAFVQELKLKQILQSDKERHEKVKRIYQEASMQQGEL    853  

gi|195391536|ref|XP_002054416.1|: domain 1 of 1, from 9 to 842: score 1261.8, E = 0
                   *->keedreeKK.........KAvakiqkefNPFdvkvakrKFdilGrsK
                      + +++ +KK+ +++++ + A+a + k+ NPFdv+v+k+KF+ilGr  
  gi|1953915     9    NADAVYSKKsvkssnpfdTAIAQTAKRLNPFDVHVNKEKFKILGR-- 53   

                   tkvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhL
                    ++K+++G PGVSRaka++kR  Tl+ ++++k+K++ f+D RiG   khL
  gi|1953915    54 -ICKHDRGLPGVSRAKALQKRSETLGRQYAVKHKTNKFVDHRIG---KHL 99   

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   sGDqL+E++M++Rf+ E+++Q+r +  +a+++n  l+D+e++++rg++  
  gi|1953915   100 SGDQLTESVMNARFLSEKLAQVR-ASNKAEKFN--LNDDELLTHRGQT-- 144  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                      l+++e++++e+sdd+  +de L + f+  ++F+++++  +++q    
  gi|1953915   145 ---LEEIEQYRDERSDDEDIDDEGLNAEFTSTAHFGGDGDTPQDRQT--- 188  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                        ++eE+I ++K++K+E+aK K+ev Dl++kLD+N+k Ll+l+a  k
  gi|1953915   189 -----AIEEMISEQKRRKNEIAKDKDEVHDLTEKLDANYKELLPLVA--K 231  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                    t      K+++  k+++Da YD+llkEM+fe+R+s++d+++ +EElA++
  gi|1953915   232 AT------KDEQHEKPPPDA-YDKLLKEMIFEPRGSVTDKLIDPEELAKQ 274  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   Ea++L +LE+eRl+RM++++E  + E+         +  +rS+dDLdD  
  gi|1953915   275 EAARLDKLENERLRRMKADGE--EQEA-------NVQIPHRSADDLDD-- 313  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                            G++           ++ +d++dd +a+d+d+    n+Gt+l
  gi|1953915   314 ---------GYFA----------AGNEDDGDDILAYDLDG----NLGTHL 340  

                   kqkKea.vLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                   + k+ea+   +  +e D+     ED e  +Dd e e E SD+E+d+l+dL
  gi|1953915   341 NSKREAgDATGQSDEKDN--ESEEDGE-NDDDDEEETEDSDSEVDNLSDL 387  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke+ +++  gea+    k K    K ++T    +d+sip+ti++Pkt+e+
  gi|1953915   388 KESDSESDQGEAPQPKNKTKPQKQKTSET----VDTSIPYTIKMPKTYED 433  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   ++eLl k    +  +IVeRIik++hpKL+++N +e++vK++++LLq+IKD
  gi|1953915   434 FTELLAKYTPTQQVTIVERIIKCNHPKLEGVN-RENVVKLYAFLLQYIKD 482  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                   +fED+seQdi+ +  fqL   L+++L+ l+ ++P +    +s++ll+vik
  gi|1953915   483 MFEDASEQDIRLH--FQLVAQLMPHLYDLTHLNPDR----MSNTLLDVIK 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+++ey+kn h+ yP l++L++FkLv++l+sTSDfrH+  TP  ++m++ 
  gi|1953915   527 EKYAEYRKN-HKVYPTLDTLIYFKLVSNLYSTSDFRHPLATPTYIFMQHI 575  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   Lsr +v++++dIa+Glf+ +i L+f s SkR++P+V+++l +i++ + +p
  gi|1953915   576 LSRARVRTRQDIAMGLFIITIALEFGSRSKRLLPAVFNFLLGIVH-MAIP 624  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDL
                   KR V +++i+P +Ferd  ++++k   l++++a  es  le q+L+ aDL
  gi|1953915   625 KRQVDQIEIVP-PFERD--GPFSK---LLAIPATSESKTLESQQLQAADL 668  

                   VtqtiteefpvdalrsSlLliKE.vleLvEeiveiyyklqAFiEIflPIl
                   Vt tit +f+v+al+  l l+K   +e + e+ +++++++       P+l
  gi|1953915   669 VTHTITLDFKVRALDITLRLVKQiFEEQIGEHTGACFLAS-------PFL 711  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                    L  +++l + +p + ++++   a   +e  ++   k++KPLA+  +KP+
  gi|1953915   712 PLMELLPL-KLYPKH-VQQHFAEAKSTLECVAA---KKMKPLAPPDKKPK 756  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                   a+rlleP+FE +yDDKR+P++s     k ++e++KL++k+KrEkKGAiRE
  gi|1953915   757 ALRLLEPRFEVVYDDKRRPKMS-----KQKEERAKLLHKIKREKKGAIRE 801  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +R+D+ Fv+ l+lk+++++d+erhEK+k+i++e+++q+g+l   
  gi|1953915   802 IRRDTAFVQDLKLKQQLQSDKERHEKVKRIYQEASVQQGEL    842  

gi|195349083|ref|XP_002041076.1|: domain 1 of 1, from 2 to 753: score 1250.7, E = 0
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +  +r+                        + + +          Gk
  gi|1953490     2    SFVARSLI----------------------RNVPLM---------GK 17   

                   PGVS..RakaeekRkrTle.aefkkknKsgafiDkRiGErnkhLsGDqLe
                      S+++++a  +  +T   a   + +    f+    G     L     +
  gi|1953490    18 AILSqqKQIAARLLHQTAPlAAVRVQHPAPDFK----G-----LA----V 54   

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDs
                    +         +   ++            lED  e      s        
  gi|1953490    55 VDNSF------Q--EVK------------LEDYRESIWCCSS-------- 76   

                   leelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEV
                    ++                  df+a+++F++e+++a+++q+        +
  gi|1953490    77 -THW-------------I--SDFTAAAHFGGEGDSAQDRQA--------A 102  

                   meEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKs
                   ++E+I+++K++K+E+aKeK+ev Dl++kLD+N+k+Ll+l+a  k t    
  gi|1953490   103 IDEMIVEQKRRKNEIAKEKDEVFDLTEKLDANYKLLLPLVA--KAT---- 146  

                   GiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLr
                     K+ ++ak+++Da YD+llkEM+fe+R+s++d++++++ElA++Ea++L+
  gi|1953490   147 --KDVQDAKPPPDA-YDKLLKEMIFEPRGSVADKLINPDELAKQEAARLE 193  

                   eLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDK
                   +LE+eRl+RM++++E e++E       S++k+k+rS+dDLdD        
  gi|1953490   194 KLENERLRRMRADGE-EEEET------SIAKPKHRSADDLDD-------- 228  

                   PKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKea
                      G+++          ++E dE+dd++a+d+d+    n+Gt+l++kKea
  gi|1953490   229 ---GYFL----------AGEGDEGDDTLAYDLDG----NLGTHLNGKKEA 261  

                   vLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp
                     k+ EneDDd      D+eGee++EeD+dEESD+E+d+l+dLKe+e+++
  gi|1953490   262 EAKGNENEDDD------DEEGEEEEEEDSDEESDSEVDNLSDLKESESES 305  

                   lkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkk
                   +++ea+kas k+KA  KKsadTiPASLd+sipFti++Pkt+e ++eLl+k
  gi|1953490   306 EPEEAPKAS-KKKA--KKSADTIPASLDTSIPFTIKMPKTYENFTELLSK 352  

                   ldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlse
                   +++++k +I+eRIik++hpKL+++N +e++vK++++LLq++KDLfED+se
  gi|1953490   353 HATAQKVTIIERIIKCNHPKLEGVN-RENVVKLYSFLLQYLKDLFEDASE 401  

                   QdikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeyk
                   Qdi+++  fqLL+kL+++L+el+q++Pe+    +s++llevike++ e++
  gi|1953490   402 QDIREH--FQLLSKLMPHLYELTQLNPER----MSNTLLEVIKEKYGEFR 445  

                   knEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvs
                   kn h++yPSl++Lv+FkLv++l+sTSDfrH+VvTP++++m++vLsrs+v+
  gi|1953490   446 KN-HKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFMQHVLSRSRVR 494  

                   SlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVell
                   ++++I++GlfLv++VL+f+s+SkR+vP+++++lq+i++ +++pKRDVe+l
  gi|1953490   495 TRQEISMGLFLVTVVLEFVSQSKRLVPAIFNFLQGIVH-MSIPKRDVEQL 543  

                   sitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtite
                   +itP +Ferd  ++l+k   l++l+a++est+lepqr ++ DLVtqtit+
  gi|1953490   544 EITP-PFERD--GPLSK---LLALPANMESTKLEPQRMQPSDLVTQTITP 587  

                   efpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrysl
                   +f+v+al++SlLliKE+l+LvEe+ +++y++q       P+l LLsr++l
  gi|1953490   588 DFKVRALDTSLLLIKEALQLVEEHDGACYLAQ-------PFLRLLSRLPL 630  

                   keslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePK
                     s+pe+ ++++++ a+el+eKl++   +++KPLA++e+KP+a+rlleP+
  gi|1953490   631 -DSYPEH-VHQHHKEATELAEKLAA---QKMKPLAPAEKKPKALRLLEPR 675  

                   FEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFv
                   FE++yDDKR+P++s     k+++e++KL++k+KrEkKGAiRE+R+D+ Fv
  gi|1953490   676 FEAVYDDKRRPKMS-----KAKEERAKLLHKIKREKKGAIREIRRDTAFV 720  

                   arlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ++lRlk+++++d+erhEK+k+i++e+++q+g+l   
  gi|1953490   721 QTLRLKQTLQSDKERHEKVKRIYQEASVQQGEL    753  

gi|213408040|ref|XP_002174791.1|: domain 1 of 1, from 37 to 832: score 825.7, E = 2.8e-245
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      + e r++K     ki ++fN Fd++ ++ KF i  +   k Kg+eG 
  gi|2134080    37    SREERASK---LDKIHSDFNRFDRQYTRQKFEIINK---KTKGTEGR 77   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+SR+++ee RkrT++ ++k kn++ga++D+R+GE+n++L+     EeK
  gi|2134080    78 PGISRGVGEEIRKRTIGEKLKRKNRTGAIVDRRFGENNPLLT----PEEK 123  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   Ml Rfs E+   ++L+  e+ + +   E v+++G r++s       +le 
  gi|2134080   124 MLQRFSLEQ--KRQLASSELTLAD---EEVLTHGSRPLS-------ELET 161  

                   lgee.LsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVme
                   l++  +sddd   d +  +++ ++++F e+  e e   r  kK+K EVm 
  gi|2134080   162 LDDHaRSDDDMDMDGE-IVRRAHFGGFDEDEEEDEGGER--KKTKHEVMQ 208  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   EiIaKSK+yKaEr++eKe  e +++kLDe + d++sll+ +    RKs  
  gi|2134080   209 EIIAKSKRYKAERQAEKEQLEEEREKLDEEMDDIQSLLSNYARETRKSAG 258  

                   KkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreL
                   K+     +  D +YD +++EMvf+ RA+Ps+RTKTeEE+Aq Ea++LreL
  gi|2134080   259 KEVKLEPTKEDVRYDAFVREMVFDRRARPSERTKTEEEIAQAEADRLREL 308  

                   EeeRlkRM.eeteEledgEeEiGGEESvkklkvrSvdDL...dDsfsVEE
                   Ee+Rl+RM+++     dg e              S +D   +d +++V  
  gi|2134080   309 EEQRLQRMhNAKAGYADGRE------------GDSLEDDyvpDETDNV-- 344  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                       fGf+e+l  +ED    eE++ +  +++e ++               
  gi|2134080   345 ----FGFGEGLTAKED---DEESFTGFQSGSESEES-----A-------- 374  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                                      D e  +DdE     +                
  gi|2134080   375 -------------------DDE--VDDEATHKKS---------------- 387  

                   qplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLl
                      kg+ +     eK   K             +++t++cP th  +l+ l
  gi|2134080   388 --SKGKTVRFALDEKPSRKNGGKK-------ELAYTYECPLTHAHFLDML 428  

                   kkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDl
                    +l  eD+ +++ RI+++hh KL++eN K +l+KF  vL +hI  L+  l
  gi|2134080   429 DGLNVEDHDTVITRIRTLHHMKLHPEN-KGRLEKFAIVLVKHI--LY--L 473  

                   seQdikknLNfqLLekLveaLielaqelPeklaislseellevikelaee
                   s Q ++    f   +    +L  +a   + + a  ++ +l ++ k+la +
  gi|2134080   474 STQQSIP---FGVINQVAQHLMRMAETYSLAIANTFRAVLTGMQKRLADS 520  

                   ykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrsp
                   y    +  +P + dLvf++ + ++F+TSD +H+Vv+Pa+l mae+ s+s+
  gi|2134080   521 YADS-EVTFPANYDLVFLNTIPSIFPTSDLKHPVVSPAMLIMAESISQSK 569  

                   vsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVe
                    ++l d   + fLv+++ k+q+iSkRyvPe  +a+ q L   l p     
  gi|2134080   570 CQTLADWTRKMFLVNLFVKYQRISKRYVPETLNAIAQLLV-VLSP----V 614  

                   llsitPLtF...erdRLDslekGLPldnlfavkestllepqrLslaDLVt
                    l+  P+ F+ ++++   s +k       f +++++l+ p + sl D   
  gi|2134080   615 ALEKAPGAFpltAQI-WSSGQK-----HEFGIQDISLDAPTKISLND--- 655  

                   qtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLL
                      +       l+sSlLl+  vl+Lv +  + + +  A+ E f PIl LL
  gi|2134080   656 ---LGTMEALELQSSLLLV--VLNLVKGTADLFNGQAAYLEMFEPILSLL 700  

                   sryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIr
                     y+  e+l+   l  +l  +   v+Kl e a+  rKPL lq+H+P+aI 
  gi|2134080   701 GIYTENEKLLHPELAAHLHTVHDHVSKLVEKARELRKPLQLQQHRPIAIS 750  

                   llePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRK
                    + PKFEE y       k   D D eR elnKL+a+++++++GAiR+lR+
  gi|2134080   751 AQLPKFEERY----TVEKH--DMDAERNELNKLRAQHRDARRGAIRTLRR 794  

                   DakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   Da+Fvar+R kE++ k ++++EKm+k++n+lq+++ A+   
  gi|2134080   795 DAQFVARERSKEQREKTKAYNEKMRKLENRLQHFDSAV    832  

gi|225423408|ref|XP_002273322.1|: domain 1 of 1, from 26 to 960: score 809.0, E = 3.1e-240
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       +  +++K KA      + NPF+ + ++ KFdilG+   k+Kge   
  gi|2254234    26    APNSVAMKLKA-----PQSNPFETIWSRTKFDILGK---KRKGEQKR 64   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                    G  R +a++kR  Tl +e++++ Ks++f+DkRiGE+n+ L+    e++K
  gi|2254234    65 IGLARSRAIQKRNATLLKEYEQSAKSSVFLDKRIGEQNDALG----EFDK 110  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + R++REr  Ql+L K++ ynl+DG+ED  e    +  S +DD++    
  gi|2254234   111 AILRSQRER--QLKLKKKSKYNLSDGEEDEFEIEGVPSFSERDDFEDEMV 158  

                   lgeeLsdddELa.....................................d
                   ++++ +d+ E a++++     +++ +  + ++ + +++   ++    + +
  gi|2254234   159 PDDDDDDGAEGAgtesliwllgpgfglleagsvglrpslvfdscffwdlS 208  

                   eaLDkdflal...........krFeeeDAeae........eeqrGAkKsK
                   +    +++ +   ++++++  k  +  D  ++++++  ++ee +  +KsK
  gi|2254234   209 DINIHRLTVFfflstekptllKQVNAHDMQNQsqrglmegEENK--HKSK 256  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklts
                   kEVmeEiI KSK+yKa +aK +ee e l ++LD+Nf +L+ ++a  +lt 
  gi|2254234   257 KEVMEEIISKSKFYKAQKAKDREENEHLVEELDKNFTSLVQSEALLSLT- 305  

                   RKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEae
                           r+ ke +D  YD+ + EM ++ RA+PsdRTKT+EE+Aq+E+e
  gi|2254234   306 --------RPDKEQPDS-YDKIIGEMTLDMRARPSDRTKTPEEIAQEERE 346  

                   kLreLEeeRlkRMee.....teE.ledgEeEiGGEESvkklkvrSvdDLd
                   +L+ LEeeR kRM +++++++eE+++ +++    E S  +l+ +S+dDL+
  gi|2254234   347 RLERLEEERQKRMLApndssDEEgDSREDA---VEASNQRLRSISGDDLG 393  

                   DsfsVEEDKP..KfGfiedlleREDNvdNeEddEdddeeae....dsdDd
                   Dsfs  +  P++K G+  ++l+R D  + e +d +  ee+e+++++sdD+
  gi|2254234   394 DSFSL-DVLPesKKGWVYEVLDRKDTNELETEDYGSSEESEspenESDDE 442  

                   dsvndGtdlkqkKeavLkddEneDDd.LGAEL...EDkeGeeDdEeDedE
                     + d    +      Lkd+E++DDd+L  +L+++ED+eGe + EeD+ E
  gi|2254234   443 GFEKD--NDNCEMTSSLKDWEQSDDDkLSTDLegeEDEEGEQEGEEDDEE 490  

                   ESDaEldvlkdLKedeaqplkgeai.kasvke.KANmKKsadTiPASLdr
                   E    l  +++ K++  +     +i++   k+ K+N+K  ++      + 
  gi|2254234   491 E-EKVLKIHQKAKDSGNAEINRNNIdSLDAKKiKTNVKHPSSQ-----QD 534  

                   sipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKek
                   sip+ i+ P++ eel  Ll+ ++  D   I+ RI++ + + L+ eNRK++
  gi|2254234   535 SIPYVIKAPTSLEELFMLLENCSDSDIVEIIHRIRINNAISLAVENRKKM 584  

                   lvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPek
                   +v F+ vLLq+        ++++ kk+LNf LL+ Lv++L e++ e+P++
  gi|2254234   585 QV-FYGVLLQYF-------AVLANKKPLNFKLLNLLVKPLMEISVEIPYF 626  

                   laislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfr
                   +ai++++++l ++ +++e++k +E   +PSlk+L++++L++ +F++SDfr
  gi|2254234   627 AAICARQRILRTRMQFCEAIKIPEKSSWPSLKTLFLLRLWSMIFPCSDFR 676  

                   HlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   H+V+TPa llm+e+L+r+p+ S+ dIaiG fL+s V k q  S+++ Pe 
  gi|2254234   677 HVVMTPATLLMCEYLMRCPILSGYDIAIGCFLCSMVVK-Q--SRKFCPEA 723  

                   vyalqqiL...............ftllvpKRDVellsitPLtFerdRLDs
                   + +lq  L    +++++ +++++f + ++    el+ ++PL+ +r     
  gi|2254234   724 IMFLQTLLmvaldgnsklsqdsqF-YFFM----ELKTLKPLLAIRG---- 764  

                   lekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLli
                            +    ++ +l ++  +         +  f++d +r+  L +
  gi|2254234   765 --------HVDDLSPLDFLTLMAMP-EG------SSFFSSDNFRACVLVS 799  

                   KEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkekll
                     ++e++ ++v+iy++  +F+EIflPI++LL ++  +e +p   lkek+ 
  gi|2254234   800 --IIETLQGFVDIYGGYNSFPEIFLPISTLLLALAEQENMPNA-LKEKIR 846  

                   davelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdks
                    +  l+  +t +++  r PL +++ KPv I l +PKFEEn+    + + +
  gi|2254234   847 GVEVLIKEKTHEHHMLRQPLQMRKQKPVPIKLFNPKFEENF----VKGRD 892  

                   SyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqe
                    yDpD+eR+e  KLk+ +K E+KGA RElRKD +F   ++   ka ++ e
  gi|2254234   893 -YDPDRERAEQRKLKKLIKQEAKGAARELRKDNYFLFEVKKRDKAMQEEE 941  

                   rhEKmkkivnelqeqegAl<-*
                   r+EK +k+ ++lqeqe+A+   
  gi|2254234   942 RAEKYGKARAFLQEQEHAF    960  

gi|270240090|emb|CBI27323.1|: domain 1 of 1, from 1 to 886: score 801.3, E = 6.5e-238
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                            +K KA      + NPF+ + ++ KFdilG+   k+Kge   
  gi|2702400     1    ------MKLKA-----PQSNPFETIWSRTKFDILGK---KRKGEQKR 33   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                    G  R +a++kR  Tl +e++++ Ks++f+DkRiGE+n+ L+    e++K
  gi|2702400    34 IGLARSRAIQKRNATLLKEYEQSAKSSVFLDKRIGEQNDALG----EFDK 79   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + R++REr  Ql+L K++ ynl+DG+ED  e    +  S +DD++    
  gi|2702400    80 AILRSQRER--QLKLKKKSKYNLSDGEEDEFEIEGVPSFSERDDFEDEMV 127  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeae........eeqrGAkK
                   ++++ +d+ E a  +  k  + lk  +  D  ++++++  ++ee +  +K
  gi|2702400   128 PDDDDDDGAEGAGTE--KKPTLLKQVNAHDMQNQsqrglmegEENK--HK 173  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   sKkEVmeEiI KSK+yKa +aK +ee e l ++LD+Nf +L+ ++a  +l
  gi|2702400   174 SKKEVMEEIISKSKFYKAQKAKDREENEHLVEELDKNFTSLVQSEALLSL 223  

                   tsR.....................KsGiKkpreak....edtDaeYDlll
                   t R+++ +  +   +++ +++  +K  +   + +k+ ++e +D  YD+ +
  gi|2702400   224 T-RpdkvnalkalvnksipneymkKDDVSAMQHIKsfkqEQPDS-YDKII 271  

                   kEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee.....teE
                    EM ++ RA+PsdRTKT+EE+Aq+E+e+L+ LEeeR kRM +++++++eE
  gi|2702400   272 GEMTLDMRARPSDRTKTPEEIAQEERERLERLEEERQKRMLApndssDEE 321  

                   .ledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP..KfGfiedlleR
                   +++ +++    E S  +l+ +S+dDL+Dsfs  +  P++K G+  ++l+R
  gi|2702400   322 gDSREDA---VEASNQRLRSISGDDLGDSFSL-DVLPesKKGWVYEVLDR 367  

                   EDNvdNeEddEdddeeae....dsdDddsvndGtdlkqkKeavLkddEne
                    D  + e +d +  ee+e+++++sdD+  + d    +      Lkd+E++
  gi|2702400   368 KDTNELETEDYGSSEESEspenESDDEGFEKD--NDNCEMTSSLKDWEQS 415  

                   DDd.LGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaik
                   DDd+L  +LED     +  +    +                       + 
  gi|2702400   416 DDDkLSTDLEDSG-NAEINRNNIDS-----------------------LD 441  

                   asvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkp
                   a  k K+N+K  ++      + sip+ i+ P++ eel  Ll+ ++  D  
  gi|2702400   442 AK-KIKTNVKHPSSQ-----QDSIPYVIKAPTSLEELFMLLENCSDSDIV 485  

                   lIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknL
                    I+ RI++ + + L+ eNRK+++v F+ vLLq+        ++++ kk+L
  gi|2702400   486 EIIHRIRINNAISLAVENRKKMQV-FYGVLLQYF-------AVLANKKPL 527  

                   NfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhiky
                   Nf LL+ Lv++L e++ e+P+++ai++++++l ++ +++e++k +E   +
  gi|2702400   528 NFKLLNLLVKPLMEISVEIPYFAAICARQRILRTRMQFCEAIKIPEKSSW 577  

                   PSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIai
                   PSlk+L++++L++ +F++SDfrH+V+TPa llm+e+L+r+p+ S+ dIai
  gi|2702400   578 PSLKTLFLLRLWSMIFPCSDFRHVVMTPATLLMCEYLMRCPILSGYDIAI 627  

                   GlfLvsiVLkfqsiSkRyvPeVvyalqqiL...............ftllv
                   G fL+s VL  + +S+++ Pe + +lq  L    +++++ +++++f + +
  gi|2702400   628 GCFLCSMVLSVVKQSRKFCPEAIMFLQTLLmvaldgnsklsqdsqF-YFF 676  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                   +    el+ ++PL+ +r              +    ++ +l ++  +   
  gi|2702400   677 M----ELKTLKPLLAIRG------------HVDDLSPLDFLTLMAMP-EG 709  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                         +  f++d +r+  L +  ++e++ ++v+iy++  +F+EIflPI+
  gi|2702400   710 ------SSFFSSDNFRACVLVS--IIETLQGFVDIYGGYNSFPEIFLPIS 751  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                   +LL ++  +e +p   lkek+  +  l+  +t +++  r PL +++ KPv
  gi|2702400   752 TLLLALAEQENMPNA-LKEKIRGVEVLIKEKTHEHHMLRQPLQMRKQKPV 800  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                    I l +PKFEEn+    + + + yDpD+eR+e  KLk+ +K E+KGA RE
  gi|2702400   801 PIKLFNPKFEENF----VKGRD-YDPDRERAEQRKLKKLIKQEAKGAARE 845  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   lRKD +F   ++   ka ++ er+EK +k+ ++lqeqe+A+   
  gi|2702400   846 LRKDNYFLFEVKKRDKAMQEEERAEKYGKARAFLQEQEHAF    886  

gi|50291321|ref|XP_448093.1|: domain 1 of 1, from 35 to 784: score 796.7, E = 1.5e-236
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFd....ilGrsKtkvKg
                      k +d eeK + +aki+ +fNPF+vk +k+K++++++ l+     ++ 
  gi|5029132    35    KKYDHEEKARTIAKIRDRFNPFEVKTTKNKRKggdpGLLN---SDRV 78   

                   eeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqL
                   ++GkPG+S++++ee R+r++ea++ +k + g++iDkR+GEr+k L+    
  gi|5029132    79 AVGKPGISKQIGEEARRRAFEAKKLMKKRKGGVIDKRFGERDKTLT---- 124  

                   eEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedG....drggsSvK
                   eEeKMleRf+REr  Q   S r+ +++n  lED+ edG+ + d++g    
  gi|5029132   125 EEEKMLERFTRER--QAG-SQRKKNLFN--LEDDDEDGpielDMFG---- 165  

                   DDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkK
                        l++lge+Ls+ d L+  a  +d         eD e  ++qr  kK
  gi|5029132   166 ---NKLTHLGESLSLADDLNVQA--EDT--------EDLEEGQPQR--KK 200  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   +K EVm+EiIaKSK+ K+Er++++ + eD id+LDe f d++ +l+ ++ 
  gi|5029132   201 TKLEVMKEIIAKSKFHKQERQAAQRKLEDNIDELDEDFDDVMAELMTTQT 250  

                   tsRKsGiKkpreakedt.DaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                           k+ +++ + + + YD+++kE+ +ekRA+P+dRTKTeEEl ++
  gi|5029132   251 L-------KQDDIEVPAeEKDYDIKVKELNLEKRAAPADRTKTEEELQKE 293  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   ++e+  +LEe+Rl RM+++ E+e+gEe             r+v+DLdD  
  gi|5029132   294 AEERRQKLEEQRLNRMQGMLEDEEGEE-------------RGVEDLDD-- 328  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                            Gf+            +E  E+++  ++ sd           
  gi|5029132   329 ---------GFWG---------SDSEVEEGEN--IANSDE---------- 348  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                                          D+e         +E+            
  gi|5029132   349 -----------------------DIE---------VES------------ 354  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                           +eai+   ++K                     i cP th e+
  gi|5029132   355 ------SSEEAISYK-SKKL------------------VAISCPQTHPEF 379  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                   l  lk+l+l   p+ V+ Iika++pKL+e+N K kl +Fs vLL+h+  +
  gi|5029132   380 LNDLKGLSLLEQPIHVKAIIKAYQPKLAEGN-KVKLANFSKVLLKHM--I 426  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                   +  l++Q + k   +  + k+++    +++ l+ek++   se+ +e+i  
  gi|5029132   427 Y--LANQRYDKD--LIKFDKTQNEFLIILKRLSEKYNQAISEVSREYILD 472  

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                    +e++kk   + ++ ++d +fF +vg lFsTSD++HlVvTPa + ++e+L
  gi|5029132   473 IQERFKKQ-NFHALNNGDILFFIIVGVLFSTSDQYHLVVTPAQIILCEFL 521  

                   srspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpK
                   +++++ Slk+Ia G++L +i+L++q+ SkRy+Pe vy+lq++L+ l v  
  gi|5029132   522 EQIRFKSLKRIAVGSVLLRIILQYQRLSKRYIPETVYFLQKALLSLVVNP 571  

                   RDVellsitPLtFerdRLDslekGLPld..nlfavkestllepqrLslaD
                    D+e     P     +RLD +  GL l ++ l+    + l e+ + s++ 
  gi|5029132   572 DDIESDMTLP-----IRLDTFDCGLKLKepSLPDDAVVHLHELFTKSTTN 616  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                          e+++   l  S L+  + + L+  +   +  + AF+EI   + 
  gi|5029132   617 ------EEDLKINVL--SNLFE-DLEKLIGSH---WNNEAAFPEICEIFE 654  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                     Ls y  ++    +   e ++ +++   Kl       + PLAlq H+P 
  gi|5029132   655 PILSVYKVRYPSITT--VESIEEKIKRMKKLNK-----HYPLALQAHRPT 697  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                   aI++ +PKFEEn+    +P k+SyD D +R e nK+ka+lK+E+K+ ++E
  gi|5029132   698 AIPSYAPKFEENF----NPAKKSYDTDVARNEVNKMKAQLKKERKFVMKE 743  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   lRKD+kF+ar+R+ Ek ++  ++h Km  i n+++++egA+   
  gi|5029132   744 LRKDTKFEARQRIDEKKKEAEAYHSKMSNIINTINTEEGAE    784  

gi|255552772|ref|XP_002517429.1|: domain 1 of 1, from 2 to 852: score 788.9, E = 3.3e-234
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        +++ +                   +k+K +   +           
  gi|2555527     2    AKTAKRSG----------------SDTKNKKK---K----------- 18   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                      S+  +   Rk+Tl +e++++ Ks++f+DkRiGE+n++L     e++K
  gi|2555527    19 ---SKKSGPNTRKKTLLKEYEQSGKSSVFVDKRIGEKNDELE----EFDK 61   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + R++REr  Q +LSK++ ynl+DG+E + e  ++g  S +DD+D++ +
  gi|2555527    62 AIMRSQRER--QMKLSKKSKYNLSDGEEEDFEIPNLGPLSERDDFDEGML 109  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   ++++ +            d       +e +A   ee++  +K+KkEVmeE
  gi|2555527   110 SDDDNDAPYGTTTLK-QLDAHDTPNLREQGALEGEEKK--HKTKKEVMEE 156  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   +I KSK+ Ka +aK Kee e l++ LD+ f +L+ +    +lt    G  
  gi|2555527   157 VILKSKFFKAQKAKDKEENEQLMEDLDKSFTSLVQSRVLLSLT--EPGKM 204  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +   a  + D +       M+++ RA+PsdRTKT+EE+Aq+E+e L+ LE
  gi|2555527   205 NALKALVNKDIP-----DGMILDMRAHPSDRTKTPEEIAQEEREQLERLE 249  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV.EEDKPK
                   eeR kRM +t   +d+E +     S    +  S+dDL+Dsfs +EE K K
  gi|2555527   250 EERRKRMLATNNSSDEENDDVEKQSMQSIRSVSGDDLGDSFSLqEEPKAK 299  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeav.
                    G+ +++leR D  d e +d    e +e  +D d+ + G d     e+ +
  gi|2555527   300 KGWVDEILERRDVEDSENEDLNLSEDSERAED-DGDSEGSDDSDSGEHNd 348  

                   .......LkddEneDDd.LGAELEDkeGeeDdEeDedEESDaEldvlkd.
                   +++++ +Lkd+E++DDd+LG +LE  e e D   D  EE   E +  k++
  gi|2555527   349 endkplsLKDWEQSDDDnLGTDLEGDE-EYDNLDDGNEE--IEPRGQKKs 395  

                   LKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                    K+d  ++ kg +++    +K+   K  +T     + +ipF i+ Pk++e
  gi|2555527   396 KKNDDVESRKGDGVSLV-TKKT---KQHST-----EPDIPFLIEAPKSFE 436  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                   el +Ll  ++++ +  +++RI+  + +KL++eNRK+++v F+ vLLq+  
  gi|2555527   437 ELCALLDNCSNANVMVVINRIRASNAIKLAAENRKKMQV-FYGVLLQYF- 484  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                         ++++ kk+LNf+LL+ Lv++Lie+++e+P++ ai++++++l ++
  gi|2555527   485 ------AVLANKKPLNFELLNLLVKPLIEMSMEIPYFSAICARQRILRTR 528  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                    +++e++k+ E +++PS+k+L +++L++  F++SDfrH+V+TPa+llm+e
  gi|2555527   529 AQFCESIKNRESGCWPSMKTLSLLRLWSMVFPCSDFRHVVMTPAILLMCE 578  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                   +L+r+p+ S++dIa G+fL+si L    +Sk++ Pe + +lq  L    v
  gi|2555527   579 YLMRCPIFSGRDIAVGSFLCSILLSVTKQSKKFCPEAIVFLQTLLK-AAV 627  

                   pKRDV..ellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                   +++  +  + +i   + e+  L+sl        + ++ ++++  ++  + 
  gi|2555527   628 EQKSAsyRESQIYH-LVELKSLGSLLF--MRHCVNEINPLNFFMIMDMP- 673  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                    D      +  f++d +r+S L    ++e++ + v+iy +l++F+EIflP
  gi|2555527   674 ED------SSFFSSDNFRASVLVT--AIETLRGYVDIYEGLPSFPEIFLP 715  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                   I++LL     +  l    l+ k +d+++l+ K++++++  r PL +++ K
  gi|2555527   716 ISTLLLEVAKQQNLSAI-LQDKFKDVAQLIKKKADEHHMLRRPLQMRKQK 764  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv I ll+PKFEEn+    + + + yDpD+eR e++KL + l+rE+KGA 
  gi|2555527   765 PVPIKLLNPKFEENF----VKGRD-YDPDRERVERKKLNKLLRREAKGAA 809  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RElRKD +F   ++ k ka  + er  K +k+ ++lqeqe A+   
  gi|2555527   810 RELRKDNYFLTEVKEKDKALVEEERSDKYGKARAFLQEQESAF    852  

gi|156838843|ref|XP_001643120.1|: domain 1 of 1, from 36 to 792: score 784.1, E = 9.7e-233
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKg.eeG
                      ke+dreeK K  aki+++fNPF+vk++k+K     +   k+K  ++G
  gi|1568388    36    KEYDREEKAKILAKIREDFNPFEVKASKNKKNNMVK-NEKDKMvAVG 81   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                   kPG+S++++ee+Rk +le +   kn++gaf DkR+GE+nkh +    eEe
  gi|1568388    82 KPGISKQIGEEQRKVALEMKNSTKNRTGAFMDKRFGEKNKHMT----EEE 127  

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedG...drggsSvKDDlD
                   KMleRf+ Er  Q + SK++ +++n  l+ +e+ G ++d++g        
  gi|1568388   128 KMLERFTKER--QAQ-SKKKQNLFN--LDEDEDEGfgnDMFG-------N 165  

                   sleelgeeL..sdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsK
                   sl++ g +L+ + +d+        d   lkr  + +A + + +   kK+K
  gi|1568388   166 SLTHMGKSLgfDSGDLGVGSD--NDGDGLKRSLDGGALGDDLGPARKKTK 213  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklts
                   +EVm+E+IaKSK+yK Er+K+ e++e +id LD+Nf d++s+l   ++  
  gi|1568388   214 AEVMKEVIAKSKFYKHERQKAHEKMEVQIDDLDDNFDDIMSELRGVQVE- 262  

                   RKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEae
                        K+  e k+  D+ YD ++kE+ +ekRA P+dRTKTeEE+  + + 
  gi|1568388   263 ----KKDNNEEKPTVDKDYDVKVKELLMEKRAVPTDRTKTEEEILTEQEI 308  

                   kLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE
                    + +LE++Rl+RM++  E e+gEe             r+v+DLd      
  gi|1568388   309 QKKKLEQQRLDRMNGIVENEEGEE-------------RGVEDLDN----- 340  

                   EDKPKfGfiedlleREDNvdNeEddE..dddeeaedsdDddsvndGtdlk
                          f+            eE+dE + d+e ++dsdD           
  gi|1568388   341 ------DFWG----------SEEEDEmgEDNESIADSDD----------- 363  

                   qkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKe
                                         D++ +   E D+dEE             
  gi|1568388   364 ----------------------DIK-F---ENDSDEE------------- 374  

                   deaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheell
                           + ++ +                           cP +h  ll
  gi|1568388   375 ------GHKSVSTT---------------------------CPSSHKQLL 391  

                   eLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLf
                       k  le  p+ + +I ka +pKL+e+N Ke+l+ F+ +LL+hI  Lf
  gi|1568388   392 LHFDKFKLEEQPKLIRKIVKATQPKLAEGN-KERLGRFTGILLRHI--LF 438  

                   EDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevikel
                     l+ Q++ k   +  ++  ++ Li+ ++ l+ek+++ lse+++e+  e 
  gi|1568388   439 --LADQNYSKD--IATFKEVQNSLISVLKTLSEKYNRDLSETCREITTEI 484  

                   aeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLs
                    e++k         ++dL+fF+++g ++sTSD++HlVvTP+   mae L+
  gi|1568388   485 HERFKSR-SMTKIKISDLIFFSIIGMIYSTSDQYHLVVTPCSVVMAEMLE 533  

                   rspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKR
                   + +++S  +  +G+ L +i+Lk+q+ SkR+vPe+ y+++++L   l p  
  gi|1568388   534 QLKFNSIDRLLFGATLSKIILKYQRLSKRLVPELLYFVEKALT-SLLP-- 580  

                   DVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVt
                     e   i      ++R+Ds e+ LP d       s  + ++r    +   
  gi|1568388   581 --EHENI------QIRVDSNELALPNDTKLDGFISESIQLHRIF-EE--- 618  

                   qtiteefpvdalrsSlLliKEvleLvEeiv.eiyyklqAFiEIflPIlaL
                      +ee    + ++ lL+    l ++ +++++i++  +A+ E +l     
  gi|1568388   619 -NRSEESNAELQKTLLLNL---LGTINMAItDIWKNFSAYQELMLSLTPI 664  

                   LsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaI
                   L  y      pe  l+  +ld++++++K+ e     + PL lq HKP +I
  gi|1568388   665 LECYVE--QFPELTLSSQILDKIKKLSKFNE-----HLPLTLQDHKPASI 707  

                   rllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElR
                   ++++PKFEE +    +Pdk+SyDpD++Rse+nK+ka+ K+E+K+  +E+R
  gi|1568388   708 PSHAPKFEESF----NPDKKSYDPDRTRSEINKMKAQVKKERKFMLKEMR 753  

                   KDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   KD++F+ar+R+ ++ +++ e+h+Km++i n+++++egA+   
  gi|1568388   754 KDTRFEARQRINQQKKSSEEYHAKMARIINTISTEEGAE    792  

gi|254584238|ref|XP_002497687.1|: domain 1 of 1, from 57 to 804: score 755.6, E = 3.6e-224
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k +d ee ++ +aki+++f PF++k+ak K    G+        +Gk
  gi|2545842    57    KNYDHEERQQVIAKIREQFSPFEIKAAKSKQ---GK---EKMVPVGK 97   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG S++++ee+R r +ea++++knK g+++D+R+GEr  h +    eEeK
  gi|2545842    98 PGTSKQIGEEQRQRIFEAKKAQKNKQGGVVDRRFGERSRHMT----EEEK 143  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+RE+  Q++ SK   ++++  l+D+  d d++g         l++
  gi|2545842   144 MLERFTREK--QSQ-SKSRKNLFD--LNDDDGD-DMFGA-------KLTH 180  

                   lgeeLsdd........dELadeaLDkdflalkrFeeeDAeaeeeqrGAkK
                   lg++L dd ++++ + dE++d      f    ++e++  e + e r  kK
  gi|2545842   181 LGQDLEDDfdegdlgvDEEDDKG---GFSSKRKYEDSLGEPQPESR--KK 225  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   +K+EVm E+IaKSK+yK+ r+K +e   D+i++LDe f d++s+l    +
  gi|2545842   226 TKAEVMQEVIAKSKFYKQQRQKSQEQRQDQIEELDEGFDDIMSELRSSNV 275  

                   tsRKsGiKkprea...kedtDaeYDlllkEMvfekRAsPsdRTKTeEElA
                           +p e+++++ d  +eYD +++E++++ RA+P+dRTKTeEE+ 
  gi|2545842   276 Q------RNPEEPnqeEKDKQKEYDMKVRELIMDRRAAPADRTKTEEEIK 319  

                   qkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdD
                   ++E+ek   LE++R++RM +   +edgEe              +vdDLdD
  gi|2545842   320 KEEEEKMKRLEQQRIDRMSGIVMDEDGEE-------------KGVDDLDD 356  

                   sfsVEEDKPKfGfiedlleREDNvdNeEddEdddeea.edsdDddsvndG
                               f+             E+ E+  eea +dsd        
  gi|2545842   357 -----------DFWG----------SDEEQEGSGEEAiADSDE------- 378  

                   tdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlk
                                             D         ++ E          
  gi|2545842   379 --------------------------DVQ-------LSSED--------- 386  

                   dLKedeaqplkgeaik.asvkeKANmKKsadTiPASLdrsipFtidcPkt
                          + +    i ++s                           cP +
  gi|2545842   387 -------EGEARRPIRdIS---------------------------CPDN 402  

                   heelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqh
                   h e+ + +k+     +p+IV++Iika++pKL+e+N Kekl+KF+ + L+h
  gi|2545842   403 HKEFMDMVKG-PVSEHPKIVKKIIKAYQPKLAEGN-KEKLGKFTGIILRH 450  

                   IKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseelle
                   +  +f  lseQ +  n  +  +   ++ L  ++++++ek++  ls ++++
  gi|2545842   451 M--IF--LSEQKYSGN--VPEFASVQNSLLGILKSMSEKYNHPLSDTCRD 494  

                   vikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllm
                   +ike++ ++k   h+  +S++dL fF Lvg lFsTSD++Hl+vTP+ +l+
  gi|2545842   495 IIKEMQIRFKEK-HFSGLSVGDLTFFTLVGCLFSTSDQYHLIVTPCSILI 543  

                   aevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftl
                   ae+L++++++Sl +  +G++Lv+i L++q+  kRy+PeV y+l++ L t+
  gi|2545842   544 AEFLEQIKFNSLERLGFGAVLVRISLQYQRLAKRYIPEVTYFLEKSLATF 593  

                   lvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                   l               +++  +D   + + +  +f +   + l ++ L  
  gi|2545842   594 LAN-----------DNCINFNVDTKDLAISKTQDFSKEIPSTLNLHLLF- 631  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                    +      + e+  d+  s  L+i    +L     +i++ l+AF EI + 
  gi|2545842   632 -E------SHELGDDLKASIFLNI--LDSLRIAVTTIWKNLSAFEEICVN 672  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                      LL  +    s p  ++   ll +++++ K+       + PL+lq+H+
  gi|2545842   673 TEFLLNEIIK--SFPGLKIAHQLLETIQKLKKFDQ-----HYPLSLQNHR 715  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   P+aI++++PKFEEn+    +P k+SyDp ++R e+nK+ka+lK+E+K+++
  gi|2545842   716 PLAIPSHAPKFEENF----NPEKKSYDPSRTRNEINKMKAQLKKERKFTM 761  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +E+RKD++F+ar+++ E  +    +h+Km+ i n+++++egA+   
  gi|2545842   762 KEIRKDTRFEARQKVDEDKKNAASYHAKMAQIFNTISTEEGAE    804  

gi|218193267|gb|EEC75694.1|: domain 1 of 1, from 32 to 934: score 755.3, E = 4.5e-224
                   *->keedreeKKK.AvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeG
                      ++ ++++K ++A a      NPF+ + ++rKFd+lG+   k+Kgee+
  gi|2181932    32    GPAAVAMKARgAAAAASGSNNPFEAIWSRRKFDVLGK---KRKGEER 75   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                        R  a+ kR +Tl +ef+++ Ks++f D+RiGEr+  L     e++
  gi|2181932    76 RIVRARSEAIHKRENTLLKEFEQSAKSSVFQDRRIGERDETLP----EFD 121  

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKDDlDsl
                   K + R +RE m+ l+    + ynl+D +ED e d +++ s S KDD+D+ 
  gi|2181932   122 KAILRQQREHMAKLK--RESKYNLSDDEED-EVDVHLPHSlSGKDDFDE- 167  

                   eelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVm
                   e l ++ sd++     +  k +  l         +  e+   +KsKkEVm
  gi|2181932   168 EVLLDDYSDEEGHMILS--KNRIPLQSGDVPSETGLPEGTNVHKSKKEVM 215  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                   +EiI KSK+yKa +aKe+ee e l dkLD  f  L    am +lt R + 
  gi|2181932   216 SEIILKSKFYKAQKAKEREEDEHLVDKLDSDFAMLAQTQAMLSLT-RSAR 264  

                   i..................KkpreakedtDaeYDlllkEMvfekRAsPsd
                   ++ ++ ++++ ++++ + + k+   ke +Da YD+l+kEMv++ RA+Psd
  gi|2181932   265 MdankynsstvqkdsfgltAKEIFNKEKPDA-YDKLVKEMVMDQRARPSD 313  

                   RTKTeEElAqkEaekLreLEeeRlkRMeeteEledg.....EeEiGGEES
                   RTKT+EE+Aq+E+e+L++LE eR kRM +t E +d++++++Ee   G+ S
  gi|2181932   314 RTKTPEEIAQEEKERLEKLEKERQKRMLGTAESSDEdddddEE---GDRS 360  

                   vkk..lkvrSvdDLdDsfsVEEDKPKf...GfiedlleRE........DN
                   +k ++ k +S+dDL+Dsfs   D P ++++G+ +++ eRE+++ +++ + 
  gi|2181932   361 TKLdsSKPISGDDLGDSFST--DEPARkekGWVDEIYEREgkkigedaEG 408  

                   vdNeEdd..........EdddeeaedsdDddsvndGtdlkqkKeavLkdd
                    dNeE+d+++++++++ Ed d+ aed+d ++  +d    +       +d+
  gi|2181932   409 SDNEESDddgddddddaEDGDDDAEDEDEEEDLSD----NDFGNMSARDW 454  

                   EneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp...lk
                   E++DDd          e+  EeDe E           LK  e  ++++ +
  gi|2181932   455 EQSDDD----------EVTVEEDEMEG----------LKQKEQKIsgkVV 484  

                   geaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkld
                   ++ + +s       KK +       d  +pF i+ P +  +l  Ll + +
  gi|2181932   485 KKDLQNS-------KKESNAESQVKDDNLPFVIEAPSNLKDLCSLLDGWS 527  

                   leDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQd
                       + I++RI++++++ L++eNRK+++v F+ vLLq+        ++++
  gi|2181932   528 ETEIIEIISRIRTCNSIRLAAENRKKMQV-FYGVLLQYF-------AVLA 569  

                   ikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykkn
                     +++ f L   Lv++Lie++ e P+++ai+++++l  ++ +l+e +k  
  gi|2181932   570 TQSPVRFKLIDTLVKPLIEMSGETPYFAAICARQRLIHTRTRLCEDIKVS 619  

                   EhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSl
                      ++PSlk+L++++L++l+F++SDfrH+V TP lllm+e+L+r+p++S+
  gi|2181932   620 GKSCWPSLKTLLLLRLWSLIFPCSDFRHVVATPMLLLMCEYLMRCPIQSG 669  

                   kdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll...........
                   +d+a G+fL+s VL     Sk++ Pe v +lq  L t l+++ +++ +++
  gi|2181932   670 RDVAVGSFLCSMVLVATKESKKFCPEAVVFLQSLLVTSLggnlgsdlrkk 719  

                   vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsla
                   +     el+  +P + +               + +v + ++le+      
  gi|2181932   720 INDQFLELKTMKPWLHIHE------------KVHEVNPANILEVICMD-S 756  

                   DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPI
                   D       ++f++d +++S Ll+  v e + ++v i   l +F+EIflPI
  gi|2181932   757 D------APYFSSDNFKASVLLS--VAECLRGFVIIHEELCSFPEIFLPI 798  

                   laLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKP
                   + L + +  k  lp   l+     ++el+    ++ ++ r PL +++ KP
  gi|2181932   799 SSLMQEIMDKSDLPGL-LQYIFHEVIELIKNRSDEVHASRQPLQMRKQKP 847  

                   vaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiR
                     Ir l+PKFEEny      + + yDpD+eR++++K+k++lK EkKGA+R
  gi|2181932   848 EPIRQLNPKFEENY----IKGLD-YDPDRERAQMKKMKKRLKSEKKGAMR 892  

                   ElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ElRKD +F + ++ kE+ +++qer+EK +k+ ++lqeqe+A+   
  gi|2181932   893 ELRKDNYFLSAVKEKERIKQEQERAEKYGKAMAFLQEQEHAF    934  

gi|28570320|gb|AAN08225.2|: domain 1 of 1, from 32 to 939: score 754.1, E = 1e-223
                   *->keedreeKKK......AvakiqkefNPFdvkvakrKFdilGrsKtkv
                      ++ ++++K ++     A a      NPF+ + ++rKFd+lG+   k+
  gi|2857032    32    GPAAVAMKARgaaaaaAAAAASGSNNPFEAIWSRRKFDVLGK---KR 75   

                   KgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGD
                   Kgee+  G  R  a+ kR +Tl +ef+++ Ks++f D+RiGEr+  L   
  gi|2857032    76 KGEERRIGRARSEAIHKRENTLLKEFEQSAKSSVFQDRRIGERDETLP-- 123  

                   qLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKD
                     e++K + R +RE m+ l+    + ynl+D +ED e d +++ s S KD
  gi|2857032   124 --EFDKVILRQQREHMAKLK--RESKYNLSDDEED-EVDVHLPHSlSGKD 168  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKs
                   D+D+ e + ++ sd++     +  k +  l         +  e+   +Ks
  gi|2857032   169 DFDE-EVPLDDYSDEEGHMILS--KNRIPLQSGDVPSEIGLPEGTNVHKS 215  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                   KkEVm+EiI KSK+yKa +aKe+ee e l dkLD  f  L    am +lt
  gi|2857032   216 KKEVMSEIILKSKFYKAQKAKEREEDEHLVDKLDSDFAMLAQTQAMLSLT 265  

                   sRKsGi..................KkpreakedtDaeYDlllkEMvfekR
                    R + ++ ++ ++++ ++++ + + k+   ke +Da YD+l+kEMv++ R
  gi|2857032   266 -RSARMdankynsstvqkdsfgltAKEIFNKEKPDA-YDKLVKEMVMDQR 313  

                   AsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledg.....EeEi
                   A+PsdRTKT+EE+Aq+E+e+L++LE eR kRM +t E +d++++++Ee  
  gi|2857032   314 ARPSDRTKTPEEIAQEEKERLEKLEKERQKRMLGTAESSDEdddddEE-- 361  

                   GGEESvkk..lkvrSvdDLdDsfsVEEDKPKf...GfiedlleRE.....
                    G+ S+k ++ k +S+dDL+Dsfs   D P ++++G+ +++ eRE+++ +
  gi|2857032   362 -GDRSTKLdsSKPISGDDLGDSFST--DEPARkekGWVDEIYEREgkkig 408  

                   ...DNvdNeEdd..........EdddeeaedsdDddsvndGtdlkqkKea
                   ++ +  dNeE+d+++++++++ Ed d+ aed+d ++  +d    +     
  gi|2857032   409 edaEGSDNEESDddgddddddaEDGDDDAEDEDEEEDLSD----NDFGNM 454  

                   vLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp
                     +d+E++DDd          e+  EeDe E           LK  e  +
  gi|2857032   455 SARDWEQSDDD----------EVTVEEDEMEG----------LKQKEQKI 484  

                   ...lkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleL
                   +++ +++ + +s       KK +       d  +pF i+ P +  +l  L
  gi|2857032   485 sgkVVKKDLQNS-------KKESNAESQVKDDNLPFVIEAPSNLKDLCSL 527  

                   lkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfED
                   l + +    + I++RI++++++ L++eNRK+++v F+ vLLq+       
  gi|2857032   528 LDGWSETEIIEIISRIRTCNSIRLAAENRKKMQV-FYGVLLQYF------ 570  

                   lseQdikknLNfqLLekLveaLielaqelPeklaislseellevikelae
                    ++++  +++ f L   Lv++Lie++ e P+++ai+++++l  ++ +l+e
  gi|2857032   571 -AVLATQSPVRFKLIDTLVKPLIEMSGETPYFAAICARQRLIHTRTRLCE 619  

                   eykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrs
                    +k     ++PSlk+L++++L++l+F++SDfrH+V TP lllm+e+L+r+
  gi|2857032   620 DIKVSGKSCWPSLKTLLLLRLWSLIFPCSDFRHVVATPMLLLMCEYLMRC 669  

                   pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll......
                   p++S++d+a G+fL+s VL     Sk++ Pe v +lq  L t l+++ ++
  gi|2857032   670 PIQSGRDVAVGSFLCSMVLVATKESKKFCPEAVVFLQSLLVTSLggnlgs 719  

                   .....vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepq
                   + ++++     el+   P + +               + +v + ++le+ 
  gi|2857032   720 dlrkkINDQFLELKTMEPWLHIHE------------KVHEVNPANILEVI 757  

                   rLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiE
                        D       ++f++d +++S Ll+  v e + ++v i   l +F+E
  gi|2857032   758 CMD-SD------APYFSSDNFKASVLLS--VAECLRGFVIIHEELCSFPE 798  

                   IflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAl
                   IflPI+ L + +  k  lp   l+  l  ++el+    ++ ++ r PL +
  gi|2857032   799 IFLPISSLMQEIMDKSDLPGL-LQYILHEVIELIKNRSDEVHASRQPLQM 847  

                   qeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEk
                   ++ KP  Ir l+PKFEEny      + + yDpD+eR++++K+k++lK Ek
  gi|2857032   848 RKQKPEPIRQLNPKFEENY----IKGLD-YDPDRERAQMKKMKKRLKSEK 892  

                   KGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   KGA+RElRKD +F + ++ kE+ +++qer+EK +k+ ++lqeqe+A+   
  gi|2857032   893 KGAMRELRKDNYFLSAVKEKERIKQEQERAEKYGKAMAFLQEQEHAF    939  

gi|115454017|ref|NP_001050609.1|: domain 1 of 1, from 5 to 899: score 750.4, E = 1.3e-222
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k+++ ++            NPF+ + ++rKFd+lG+   k+Kgee+ 
  gi|1154540     5    KPTAAAAA-------SGSNNPFEAIWSRRKFDVLGK---KRKGEERR 41   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                    G  R  a+ kR +Tl +ef+++ Ks++f D+RiGEr+  L     e++K
  gi|1154540    42 IGRARSEAIHKRENTLLKEFEQSAKSSVFQDRRIGERDETLP----EFDK 87   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKDDlDsle
                    + R +RE m+ l+    + ynl+D +ED e d +++ s S KDD+D+ e
  gi|1154540    88 VILRQQREHMAKLK--RESKYNLSDDEED-EVDVHLPHSlSGKDDFDE-E 133  

                   elgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVme
                    + ++ sd++     +  k +  l         +  e+   +KsKkEVm+
  gi|1154540   134 VPLDDYSDEEGHMILS--KNRIPLQSGDVPSEIGLPEGTNVHKSKKEVMS 181  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   EiI KSK+yKa +aKe+ee e l dkLD  f  L    am +lt R + +
  gi|1154540   182 EIILKSKFYKAQKAKEREEDEHLVDKLDSDFAMLAQTQAMLSLT-RSARM 230  

                   ..................KkpreakedtDaeYDlllkEMvfekRAsPsdR
                   + ++ ++++ ++++ + + k+   ke +Da YD+l+kEMv++ RA+PsdR
  gi|1154540   231 dankynsstvqkdsfgltAKEIFNKEKPDA-YDKLVKEMVMDQRARPSDR 279  

                   TKTeEElAqkEaekLreLEeeRlkRMeeteEledg.....EeEiGGEESv
                   TKT+EE+Aq+E+e+L++LE eR kRM +t E +d++++++Ee   G+ S+
  gi|1154540   280 TKTPEEIAQEEKERLEKLEKERQKRMLGTAESSDEdddddEE---GDRST 326  

                   kk..lkvrSvdDLdDsfsVEEDKPKf...GfiedlleRE........DNv
                   k ++ k +S+dDL+Dsfs   D P ++++G+ +++ eRE+++ +++ +  
  gi|1154540   327 KLdsSKPISGDDLGDSFST--DEPARkekGWVDEIYEREgkkigedaEGS 374  

                   dNeEdd..........EdddeeaedsdDddsvndGtdlkqkKeavLkddE
                   dNeE+d+++++++++ Ed d+ aed+d ++  +d    +       +d+E
  gi|1154540   375 DNEESDddgddddddaEDGDDDAEDEDEEEDLSD----NDFGNMSARDWE 420  

                   neDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp...lkg
                   ++DDd          e+  EeDe E           LK  e  ++++ ++
  gi|1154540   421 QSDDD----------EVTVEEDEMEG----------LKQKEQKIsgkVVK 450  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                   + + +s       KK +       d  +pF i+ P +  +l  Ll + + 
  gi|1154540   451 KDLQNS-------KKESNAESQVKDDNLPFVIEAPSNLKDLCSLLDGWSE 493  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                      + I++RI++++++ L++eNRK+++v F+ vLLq+        ++++ 
  gi|1154540   494 TEIIEIISRIRTCNSIRLAAENRKKMQV-FYGVLLQYF-------AVLAT 535  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                    +++ f L   Lv++Lie++ e P+++ai+++++l  ++ +l+e +k   
  gi|1154540   536 QSPVRFKLIDTLVKPLIEMSGETPYFAAICARQRLIHTRTRLCEDIKVSG 585  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                     ++PSlk+L++++L++l+F++SDfrH+V TP lllm+e+L+r+p++S++
  gi|1154540   586 KSCWPSLKTLLLLRLWSLIFPCSDFRHVVATPMLLLMCEYLMRCPIQSGR 635  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll...........v
                   d+a G+fL+s VL     Sk++ Pe v +lq  L t l+++ +++ ++++
  gi|1154540   636 DVAVGSFLCSMVLVATKESKKFCPEAVVFLQSLLVTSLggnlgsdlrkkI 685  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                        el+   P + +               + +v + ++le+      D
  gi|1154540   686 NDQFLELKTMEPWLHIHE------------KVHEVNPANILEVICMD-SD 722  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                          ++f++d +++S Ll+  v e + ++v i   l +F+EIflPI+
  gi|1154540   723 ------APYFSSDNFKASVLLS--VAECLRGFVIIHEELCSFPEIFLPIS 764  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                    L + +  k  lp   l+  l  ++el+    ++ ++ r PL +++ KP 
  gi|1154540   765 SLMQEIMDKSDLPGL-LQYILHEVIELIKNRSDEVHASRQPLQMRKQKPE 813  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                    Ir l+PKFEEny      + + yDpD+eR++++K+k++lK EkKGA+RE
  gi|1154540   814 PIRQLNPKFEENY----IKGLD-YDPDRERAQMKKMKKRLKSEKKGAMRE 858  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   lRKD +F + ++ kE+ +++qer+EK +k+ ++lqeqe+A+   
  gi|1154540   859 LRKDNYFLSAVKEKERIKQEQERAEKYGKAMAFLQEQEHAF    899  

gi|50305939|ref|XP_452930.1|: domain 1 of 1, from 36 to 822: score 739.9, E = 1.9e-219
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       e dree +K +  i+++fNPFdvk +++K +++     + K ++Gk
  gi|5030593    36    REFDREERQKTIERIREQFNPFDVKTNRNK-KVGVMRESAAKLAVGK 81   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+ ++ +e++Rk   ea++  kn+sg+++DkR+GE++k L+     Ee 
  gi|5030593    82 PGITKQAGEDQRKMFYEAKKSSKNRSGGVLDKRFGEKDKNLT----SEEI 127  

                   MleRfsRErmSQlrLS..Kreaynln..DGlEDv....eedGdrggs.Sv
                   MleRf+ Er  Q++ S++Kr++ nl+++DG ED +  +e +++ g s S 
  gi|5030593   128 MLERFTKER--QRQ-SstKRSLFNLDdsDGGEDEnvygEKLTHYGKSlSL 174  

                   KDDlDslee.lgeeLsdddELadeaLDkdflalkrFeee...DAeaeeeq
                    DD+D++ ++l  + s+d  L  +   k+ +a   +++e+ +D+ ++e+ 
  gi|5030593   175 EDDFDEGDLgLQHSDSEDFRLKQAG--KRNMA-DQYGDEglgDDALQEPA 221  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll
                   r  kK+K+EVm E+IaKSK+yK Er+K++e+    i+ LD+ f++++s+l
  gi|5030593   222 R--KKTKAEVMQEVIAKSKFYKHERQKAQEKLVQDIEGLDDDFESIMSEL 269  

                   amekltsRKsGiK.kpreakedtD...aeYDlllkEMvfekRAsPsdRTK
                       +t      K+ + e+ + tD  ++ YD+++kE+v+ekRA+P+dRTK
  gi|5030593   270 RTLPKT------KpSQTEISTSTDiapD-YDIKVKELVLEKRAAPADRTK 312  

                   TeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrS
                   T EE+ ++ ++k  eLE+ Rl+RM++    ed                 +
  gi|5030593   313 TDEEIKKEYEDKQKELEQKRLDRMNGIFNIEDQKD-------------AG 349  

                   vdDLdDsfsVEEDKPKfGfiedlleREDNvdNeE.ddEdddeeaedsdDd
                   v+DL+             f+e         d eE+++      + dsdD 
  gi|5030593   350 VEDLGE-----------EFWE-------DSDSEEgEYGEYIKAIPDSDD- 380  

                   dsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDa
                                                   D   +e d  D+ E    
  gi|5030593   381 --------------------------------DVD-FEKDNNDDNEY--- 394  

                   EldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti
                                      a ++        + sa  iP           
  gi|5030593   395 ------------------DATSNG-------RPSARVIPS---------V 410  

                   dcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsv
                   +cP  h++ll  lk    e +p  V+RI k ++pKL+e+N Kekl+KF++
  gi|5030593   411 PCPQIHDDLLNFLKSYPIEEHPSLVKRIVKTYQPKLAEGN-KEKLGKFTA 459  

                   vLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaisls
                   vLL+hI  Lf  l+e d+  n  +     L++ L ++++ l+ek  i ls
  gi|5030593   460 VLLRHI--LF--LAEEDYSVN--VKEIASLQNELVSILKTLSEKFTIPLS 503  

                   eellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTP
                   e ++ +i+  + ++k    +  +S +dLvfF+ vg lFsTSD +HlV+TP
  gi|5030593   504 EDCRNIISDIQTRFKES-QFYGLSPSDLVFFSVVGMLFSTSDHYHLVITP 552  

                   alllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqq
                   +lll+ae+L++++++Sl+   +G+ Lv+i  ++q+iSkRy+Pe+ y+lq 
  gi|5030593   553 CLLLIAEFLEQIRFNSLQKLIFGSILVRIAIQYQRISKRYIPELTYFLQT 602  

                   iLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllep
                    L   l+p    e l+ +     +   D l+      n   v +s  le+
  gi|5030593   603 SLR-SLIPSTKGETLENKE---KQE--DNLSIVGSDINWSKVAPS--LEL 644  

                   qrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFi
                   + L   D      +e   +  l s+l +    ++ +  i  i++ l AF+
  gi|5030593   645 HSLFSED------LEKQESIKL-SVLVNN--LESIDWCITNIWKDLTAFP 685  

                   EIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLA
                   EI+ P+ + L      +   +k  ++ l  ++e++ K+ e     r PL 
  gi|5030593   686 EIINPFKDILNVAAEVYPGTSK--PKQLVEKIEKLLKFQE-----RLPLT 728  

                   lqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrE
                   lq+HKP+aI++  PKFEEn+    +Pdk+SyDpDk+RselnK+ka+lK+E
  gi|5030593   729 LQQHKPLAIPSNTPKFEENF----NPDKKSYDPDKTRSELNKMKAQLKKE 774  

                   kKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-
                   +K++++E+RKD++F+ar+ ++Ek ++  ++h Km++ivn+++++egA+  
  gi|5030593   775 RKFTMKEIRKDTRFEARQGIEEKKKEYADYHSKMARIVNQISTEEGAE   822  

                   *
                    
  gi|5030593     -   -    

gi|125587033|gb|EAZ27697.1|: domain 1 of 1, from 32 to 938: score 728.9, E = 3.9e-216
                   *->keedreeKKK......AvakiqkefNPFdvkvakrKFdilGrsKtkv
                      ++ ++++K ++     A a      NPF+ + ++rKFd+lG+   k+
  gi|1255870    32    GPAAVAMKARgaaaaaAAAAASGSNNPFEAIWSRRKFDVLGK---KR 75   

                   KgeeGkPGVSRakae..ekRkrTleaefkkknKsgafiDkRiGErnkhLs
                   Kge      S a a+++  R +Tl +ef+++ Ks++f D+RiGEr+  L 
  gi|1255870    76 KGES---AASAAPALrpSTRENTLLKEFEQSAKSSVFQDRRIGERDETLP 122  

                   GDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.Sv
                       e++K + R +RE m+ l+    + ynl+D +ED e d +++ s S 
  gi|1255870   123 ----EFDKVILRQQREHMAKLK--RESKYNLSDDEED-EVDVHLPHSlSG 165  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                   KDD+D+ e + ++ sd++     +  k +  l         +  e+   +
  gi|1255870   166 KDDFDE-EVPLDDYSDEEGHMILS--KNRIPLQSGDVPSEIGLPEGTNVH 212  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   KsKkEVm+EiI KSK+yKa +aKe+ee e l dkLD  f  L    am +
  gi|1255870   213 KSKKEVMSEIILKSKFYKAQKAKEREEDEHLVDKLDSDFAMLAQTQAMLS 262  

                   ltsRKsGi..................KkpreakedtDaeYDlllkEMvfe
                   lt R + ++ ++ ++++ ++++ + + k+   ke +Da YD+l+kEMv++
  gi|1255870   263 LT-RSARMdankynsstvqkdsfgltAKEIFNKEKPDA-YDKLVKEMVMD 310  

                   kRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledg.....Ee
                    RA+PsdRTKT+EE+Aq+E+e+L++LE eR kRM +t E +d++++++Ee
  gi|1255870   311 QRARPSDRTKTPEEIAQEEKERLEKLEKERQKRMLGTAESSDEdddddEE 360  

                   EiGGEESvkk..lkvrSvdDLdDsfsVEEDKPKf...GfiedlleRE...
                      G+ S+k ++ k +S+dDL+Dsfs   D P ++++G+ +++ eRE+++
  gi|1255870   361 ---GDRSTKLdsSKPISGDDLGDSFST--DEPARkekGWVDEIYEREgkk 405  

                   .....DNvdNeEdd..........EdddeeaedsdDddsvndGtdlkqkK
                    +++ +  dNeE+d+++++++++ Ed d+ aed+d ++  +d    +   
  gi|1255870   406 igedaEGSDNEESDddgddddddaEDGDDDAEDEDEEEDLSD----NDFG 451  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                       +d+E++DDd          e+  EeDe E           LK  e 
  gi|1255870   452 NMSARDWEQSDDD----------EVTVEEDEMEG----------LKQKEQ 481  

                   qp...lkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheell
                    ++++ +++ + +s       KK +       d  +pF i+ P +  +l 
  gi|1255870   482 KIsgkVVKKDLQNS-------KKESNAESQVKDDNLPFVIEAPSNLKDLC 524  

                   eLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLf
                    Ll + +    + I++RI++++++ L++eNRK+++v F+ vLLq+     
  gi|1255870   525 SLLDGWSETEIIEIISRIRTCNSIRLAAENRKKMQV-FYGVLLQYF---- 569  

                   EDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevikel
                      ++++  +++ f L   Lv++Lie++ e P+++ai+++++l  ++ +l
  gi|1255870   570 ---AVLATQSPVRFKLIDTLVKPLIEMSGETPYFAAICARQRLIHTRTRL 616  

                   aeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLs
                   +e +k     ++PSlk+L++++L++l+F++SDfrH+V TP lllm+e+L+
  gi|1255870   617 CEDIKVSGKSCWPSLKTLLLLRLWSLIFPCSDFRHVVATPMLLLMCEYLM 666  

                   rspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll....
                   r+p++S++d+a G+fL+s VL     Sk++ Pe v +lq  L t l+++ 
  gi|1255870   667 RCPIQSGRDVAVGSFLCSMVLVATKESKKFCPEAVVFLQSLLVTSLggnl 716  

                   .......vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestlle
                   +++ ++++     el+   P + +               + +v + ++le
  gi|1255870   717 gsdlrkkINDQFLELKTMEPWLHIHE------------KVHEVNPANILE 754  

                   pqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAF
                   +      D       ++f++d +++S Ll+  v e + ++v i   l +F
  gi|1255870   755 VICMD-SD------APYFSSDNFKASVLLS--VAECLRGFVIIHEELCSF 795  

                   iEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPL
                   +EIflPI+ L + +  k  lp   l+  l  ++el+    ++ ++ r PL
  gi|1255870   796 PEIFLPISSLMQEIMDKSDLPGL-LQYILHEVIELIKNRSDEVHASRQPL 844  

                   AlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKr
                    +++ KP  Ir l+PKFEEny      + + yDpD+eR++++K+k++lK 
  gi|1255870   845 QMRKQKPEPIRQLNPKFEENY----IKGLD-YDPDRERAQMKKMKKRLKS 889  

                   EkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<
                   EkKGA+RElRKD +F + ++ kE+ +++qer+EK +k+ ++lqeqe+A+ 
  gi|1255870   890 EKKGAMRELRKDNYFLSAVKEKERIKQEQERAEKYGKAMAFLQEQEHAF  938  

                   -*
                     
  gi|1255870     -    -    

gi|242033739|ref|XP_002464264.1|: domain 1 of 1, from 27 to 910: score 726.0, E = 3e-215
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++  +++K    a   ++ NPF+ + ++rKFd+lG+   k+Kgee+ 
  gi|2420337    27    GPAKVAMK-ARGAAAEERSNPFEAIWSRRKFDVLGK---KRKGEERR 69   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   ++ SR  a+ kR +Tl +ef+ + Ks++f D+RiGEr++ L     e++K
  gi|2420337    70 VSRSRSEAIRKRENTLLKEFMESGKSSVFHDRRIGERDDALP----EFDK 115  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + R +REr++ l+    + ynl+D  ED     ++     KDD+D+   
  gi|2420337   116 AILRQQRERLAKLK--RESKYNLSDDDEDEINVHNMLSE--KDDFDEEVP 161  

                   lgeeLsdddELadeaLDkdf.lalkrFeeeDAeaeeeqrGAkKsKkEVme
                   l+++ +++         k+++l +     + +  +e     +KsKkEVm+
  gi|2420337   162 LDDGSDEEGKMVLSK--KRLsLQSDDHPSVTDLPQETHG--QKSKKEVMS 207  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   EiI KSK+yKa raKe+ee e l dkLD  f +L    a  +lt   + +
  gi|2420337   208 EIISKSKFYKAQRAKEREEDEHLVDKLDSDFASLAQTQALLSLT-DSAKV 256  

                   K............kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEE
                   K ++++++ + ++k+   k   D  Y +l+kEMv++ RA+PsdRTKT+EE
  gi|2420337   257 KvnkndssagltgKEIFNKLKADT-YEKLVKEMVMDQRARPSDRTKTPEE 305  

                   lAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkv.....r
                   +Aq+E+e+L++LEeeR kRM +t   +d++      E  k  k ++++++
  gi|2420337   306 IAQEEKERLEKLEEERQKRMLGTADSSDEDD---DNEDDKHMKLgnskpI 352  

                   SvdDLdDsfsVEEDK.PKfGfiedlleRE.....DNvdNeEddEdddeea
                   S+dDL+Dsfs +E  + K G+ +++ eRE+++ +D   ++ d E dde a
  gi|2420337   353 SGDDLGDSFSLDESIgKKKGWVDEIYEREgrkigDDAAASDDGESDDENA 402  

                   ed...sdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdE
                    d++  d +ds+ d    +       +d+E++DDd          e+D +
  gi|2420337   403 SDdgaDDEEDSEED-SSDNDFGNMSARDWEQSDDD----------EVDVG 441  

                   eDedEESDaEldvlkdLKedeaqplkgeaikasvkeKA..NmKKsadTiP
                    De E                   +k+  i + v eK  +N+K  +d  P
  gi|2420337   442 DDEMED----------------FKEKEQEINGKVVEKVahNLKGESDVKP 475  

                   ASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkee
                      d sipF id P    +l  Ll + + +    I++RI++++++ L++e
  gi|2420337   476 QVKDGSIPFVIDAPNDLKDLSSLLDGRSEAEIVEIISRIRTCNSIRLAAE 525  

                   NRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaq
                   NR++++v F+ vLLq+       l+ Q   k   f     Lv++Lie++ 
  gi|2420337   526 NRRKMQV-FYGVLLQYF----ATLATQSPVK---FRIIDTLVKPLIEMSG 567  

                   elPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFs
                   e P+++ai+++e+l  ++ +l+e +k +    +P lk+L++++L++l+F+
  gi|2420337   568 ETPYFAAICARERLIHTRTRLCEDIKVPGKSSWPNLKTLLLLRLWSLIFP 617  

                   TSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkR
                   +SDfrH+V TP lllm+e+L+r+p++S++d+a G+fL+s VL     Sk+
  gi|2420337   618 CSDFRHVVATPLLLLMCEYLMRCPIQSGRDVAVGSFLCSMVLVVTKESKK 667  

                   yvPeVvyalqqiLftll...............vpKRDVellsitPLtFer
                   + Pe v +lq  L t l+++ +++ +++ +++++    el+ ++P + + 
  gi|2420337   668 FCPEAVGFLQSLLVTSLkgkvgthlhnqindqFM----ELKTLKPWLSIH 713  

                   dRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrs
                   d             + +v ++++le+      D       ++f++d +++
  gi|2420337   714 D------------QVHEVNPVNILEIVGMD-PD------APYFSSDNFKA 744  

                   SlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRl
                     Ll+  v+e + ++v i  +l +F+EIflPI+ LL+ +  + +lp   l
  gi|2420337   745 GVLLS--VVECLRGFVIIHEGLCSFPEIFLPISSLLQEILERSELPDS-L 791  

                   keklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKR
                   +      + lv K  +++++ r PL ++++KP  I  l+PKFEEny    
  gi|2420337   792 QDIFHEIIDLVKKISDEHHASREPLRMRKKKPEPIKQLNPKFEENY---- 837  

                   sPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEka
                     + + yDpD+eR++++KL+++ K E KGA REl KD +F + ++ kE+ 
  gi|2420337   838 IKGLD-YDPDRERAQMKKLRKRVKSEMKGAKRELQKDNYFLSAVKEKERM 886  

                   akdqerhEKmkkivnelqeqegAl<-*
                   + d er+E  +k+ ++lqeqe A+   
  gi|2420337   887 KRDEERAEMYGKAMAFLQEQESAF    910  

gi|255719352|ref|XP_002555956.1|: domain 1 of 1, from 35 to 799: score 719.4, E = 2.8e-213
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+dr e  KA+a i+++fNPFdvk+++ K+    +   +v   +Gk
  gi|2557193    35    KEYDRDERTKAIARIREQFNPFDVKMNRDKRGAEAK---RVAQPVGK 78   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+Rk+  ea++k kn+ g+ +D+R+GE+ k L+    eEeK
  gi|2557193    79 PGISKQIGEEQRKQVYEAKKKSKNRLGGLLDRRFGENFKGLT----EEEK 124  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+RE+ SQ   S r++ nl+   +D+  d d  g       + l++
  gi|2557193   125 MLERFTREKQSQAS-SRRSLFNLD--DDDDAGDDDVYG-------EKLTH 164  

                   lgeeL..sdddELadeaLDkdf......lalkr.FeeeDAeaeeeqrGAk
                   +g +L+ +dd  ++d  LD+d +++++++ + r+F++e Ae+  + r  k
  gi|2557193   165 YGKSLsfQDDFQEDDLGLDEDTgnkgssKRSEReFGDENAEL--PAR--K 210  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll.ame
                   K+K+EVm+E+IaKSK+yK+Er+K++e+ eD i   D+ f+d++ +l++  
  gi|2557193   211 KTKAEVMKEVIAKSKFYKQERQKAQEKLEDDIQDVDDEFEDVMAELnSLP 260  

                   kltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAq
                   k +      K+ +      D+eYD +++E+ ++ RA+P++RTKTeEEl +
  gi|2557193   261 KAK------KTDQNNSKEFDKEYDTKVRELGLDRRAAPAERTKTEEELEK 304  

                   kEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDs
                   + +ek  +LE+ Rl+RM+++   e+++               +v+DL+  
  gi|2557193   305 ENEEKRQKLEQARLDRMRGMFG-EEEDQ--------------GVEDLGE- 338  

                   fsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                              f+                 ++d+e ed+       d   
  gi|2557193   339 ----------EFWA----------------GEDSENEDLNE----TD--- 355  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                                      G ELED e      e + +            
  gi|2557193   356 -------------------GSELEDVE-LPGGDETKSFG----------- 374  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                                   +k KA      +             i+cP t ee
  gi|2557193   375 ----------------GKSKA-----VSV------------IPCPQTEEE 391  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l + l    l  +p  V+ Ii  ++p L+ +N K kl+ F+ vLL+hI  
  gi|2557193   392 LKDFLQSYELREHPNMVKEIIRTYQPSLAMGN-KGKLGVFTGVLLRHI-- 438  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                   L   ls+    ++  ++L+   ++ Li +++++  k++  lse+++e+ +
  gi|2557193   439 LS--LSVSYDDSH--LELFGSVQNSLIAILRSMAQKYNEPLSETCREITS 484  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e +e++k+      +S  dL+fF Lvg +FsTSD +HlVvTP+  l+ e 
  gi|2557193   485 EIQERFKNE-RSHGLSTADLIFFTLVGYIFSTSDHYHLVVTPCNVLIGEL 533  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L++ + +S + + + ++L++i L +q   kR+vPe+vy++++ L tll  
  gi|2557193   534 LEQTKLNSFQNVFFCAVLARISLSYQNMGKRLVPELVYFFEKSLVTLLPL 583  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDL
                       +++s   L  +    Ds  +     n + + ++  +  ++L l   
  gi|2557193   584 --TSKEKSSSGLAHIIQ--DSEDL-----NAPQKLDLAAIGSHNLNLRQ- 623  

                   VtqtiteefpvdalrsSlL.liKEvleLvEeiveiyyklqAFiEIflPIl
                          + p d+ +s lL +i    +L E i+ +++ l++F E  l + 
  gi|2557193   624 --AMSQDYVPNDQEKSALLcNI--LASLEEAISLVWKELSSFQELTLSFK 669  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                     Ls+ s  ++++ek  ++ +l ++e+ eK+ e     + PL+lq+H+Pv
  gi|2557193   670 RILSAFSQIYEDFEK--PKVILEKIEKFEKFHE-----HFPLSLQNHRPV 712  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                   +I++++PK+EEn+    +Pdk+SyDpD++R e nK+ka+lK+E+K++++E
  gi|2557193   713 SIPSHVPKYEENF----NPDKKSYDPDRTRNEVNKMKAQLKKERKFTMKE 758  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +RKD++F+ar+ ++ k +   ++h Km++i n+++++eg +   
  gi|2557193   759 IRKDTRFEARQQIETKKKDYADYHSKMARIINQISTEEGME    799  

gi|45187945|ref|NP_984168.1|: domain 1 of 1, from 34 to 791: score 708.6, E = 4.9e-210
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ke+d eeK + v  i+++fNPFdvk+++ K    G      K ++Gk
  gi|4518794    34    KEYDHEEKARVVSAIREQFNPFDVKANRSKLHAAGA--GDAKVAVGK 78   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+S++++ee+R r  e ++++kn+ g+ iDkR+GErnkh +     Ee 
  gi|4518794    79 PGISKQIGEEQRLRFHESKKAQKNRAGGLIDKRFGERNKHMT----AEEI 124  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+ Er +Q+r SK+++ nl+    D e+dGd  g         l++
  gi|4518794   125 MLERFTKERQAQSRQSKKSLFNLD----DEEDDGDASGA--------LTH 162  

                   lgeeLsdddELadeaLDkdfl.alkrFee.eDAeaeeeqrGAkKsKkEVm
                    g  L  d E  d    +   +al+  ++  D+e e e    kK+K+EVm
  gi|4518794   163 FGKPLASDFEDGDLG--VGMAgALGPKRGlADDEMEPEVP-KKKTKAEVM 209  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll..amekltsRK
                   +E+IaKSK+yK Er+K++e +e +id LD+ f+ ++s+l+ a    t   
  gi|4518794   210 KEVIAKSKFYKHERQKAREQMEEEIDQLDDEFEGIMSELraAPRART--- 256  

                   sGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekL
                       +p e k+    eYD +++E+ ++ RA+P+dR KT EE+ q+ +ekL
  gi|4518794   257 ----NPVESKPSQELEYDQKVRELCLDRRAAPADRVKTDEEMKQEREEKL 302  

                   reLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEED
                    +LE  R  RM++      +++              +v+DLd        
  gi|4518794   303 KKLELDRVNRMNGLVD--GEDA-------------QGVEDLDN------- 330  

                   KPKfGfiedlleREDNvdNeEddEdd....deeaedsdDddsvndGtdlk
                       Gf+e          +e +d ++ ++  e ++dsdD           
  gi|4518794   331 ----GFWE----------AEDSDAGEygeyMEAIADSDD----------- 355  

                   qkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKe
                                         D +          +E             
  gi|4518794   356 ----------------------DLK----------FE------------- 360  

                   deaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheell
                      +p+  e + ++ + K   KK a               +cP th el 
  gi|4518794   361 --NEPETAE-PTGT-SHKQ--KKIAAL-------------PCPITHAELM 391  

                   eLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLf
                   + l    le  p +V++Iika++pKL+e+N Kekl KFs vLL hI  Lf
  gi|4518794   392 DVLTAYQLEEQPHVVKNIIKAYQPKLAEGN-KEKLDKFSGVLLHHI--LF 438  

                   EDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevikel
                     ls  d+ +    +     ++ Li+++++++ek++  lse ++ v  e 
  gi|4518794   439 --LSSSDYASQ--ADVIVEVQNSLISILKLMSEKYNQALSEACRQVVTEI 484  

                   aeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLs
                   + ++k   h   +  +dLvfF+Lvg +FsTSD +HlVvTP+ +l+ e+L+
  gi|4518794   485 QQRFKAQ-HYLGLKPSDLVFFSLVGYIFSTSDHYHLVVTPCCILLGEFLE 533  

                   rspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKR
                   +++     +  + +  ++i   +q+iS+R+vPe+ y+l  +L   l p  
  gi|4518794   534 QIKLTDYERLIFVAIAANICVRYQRISRRHVPELAYFLKRALA-SLLP-- 580  

                   DVellsitPLtFerdRLDslekGLPl.dnlfavkestllepqrLslaDLV
                      +  +      ++RLDs ++ L ++++l  + +  +l    L  +D  
  gi|4518794   581 ---FSTENS-QAFNIRLDSDKLSLSKtLVLEDIEPTLKLRFLFLKEYD-- 624  

                   tqtiteefpvdalrsSlLliKEvle.LvEeiveiyyklqAFiEIflPIla
                             d  ++ lL     l++L++  +  +++ +AF+E   P+  
  gi|4518794   625 ----------DSVQAQLLVN--LLStLDACVSQLWKGVSAFPELTQPFKP 662  

                   LLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPva
                   LLs+  + +  + k  ++ +    e ++ l       + PL lq+HKP a
  gi|4518794   663 LLSAFASSYPTFAK--PQQIMERMERISNLQQ-----HFPLTLQNHKPAA 705  

                   IrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiREl
                   I++  PKFE n+    +P k+SyDpD++R ++nK+ka+lK+E+K +++El
  gi|4518794   706 IPSYMPKFEDNF----NPEKKSYDPDRTRNDINKMKAQLKKERKLTMKEL 751  

                   RKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RKD+kF+ar++++E++++  ++ +Km++ivn+++++egA    
  gi|4518794   752 RKDTKFEARQKIEEQRKHADDYKAKMARIVNQISTEEGAD    791  

gi|108709667|gb|ABF97462.1|: domain 1 of 1, from 32 to 916: score 626.0, E = 3.7e-185
                   *->keedreeKKK......AvakiqkefNPFdvkvakrKFdilGrsKtkv
                      ++ ++++K ++     A a      NPF+ + ++rKFd+lG+   k+
  gi|1087096    32    GPAAVAMKARgaaaaaAAAAASGSNNPFEAIWSRRKFDVLGK---KR 75   

                   KgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGD
                   Kgee+  G  R  a+ kR +Tl +ef+++ Ks++f D+RiGEr+  L   
  gi|1087096    76 KGEERRIGRARSEAIHKRENTLLKEFEQSAKSSVFQDRRIGERDETLP-- 123  

                   qLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKD
                     e++K + R +RE m+ l+    + ynl+D +ED e d +++ s S KD
  gi|1087096   124 --EFDKVILRQQREHMAKLK--RESKYNLSDDEED-EVDVHLPHSlSGKD 168  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKs
                   D+D+ e + ++ sd++     +  k +  l         +  e+   +Ks
  gi|1087096   169 DFDE-EVPLDDYSDEEGHMILS--KNRIPLQSGDVPSEIGLPEGTNVHKS 215  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                   KkEVm+EiI KSK+yKa +aKe+ee e l dkLD  f  L    am +lt
  gi|1087096   216 KKEVMSEIILKSKFYKAQKAKEREEDEHLVDKLDSDFAMLAQTQAMLSLT 265  

                   sRKsGiKkpreakedtDaeYDll.lkEMvfekRAs.PsdRT..KTeEElA
                            r a  d  + Y ++++   +f   A++   +T      E+ 
  gi|1087096   266 ---------RSARMDANK-YNSStVQKDSFGLTAKeIFNKTfiVGCGEI- 304  

                   qkEaekLreLEeeRlkRMeeteEledg.....EeEiGGEESvkk..lkvr
                    +          eR kRM +t E +d++++++Ee   G+ S+k ++ k +
  gi|1087096   305 HIDVFFIDVMMKERQKRMLGTAESSDEdddddEE---GDRSTKLdsSKPI 351  

                   SvdDLdDsfsVEEDKPKf...GfiedlleRE........DNvdNeEdd..
                   S+dDL+Dsfs   D P ++++G+ +++ eRE+++ +++ +  dNeE+d++
  gi|1087096   352 SGDDLGDSFST--DEPARkekGWVDEIYEREgkkigedaEGSDNEESDdd 399  

                   ........EdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGA
                   +++++++ Ed d+ aed+d ++  +d    +       +d+E++DDd   
  gi|1087096   400 gddddddaEDGDDDAEDEDEEEDLSD----NDFGNMSARDWEQSDDD--- 442  

                   ELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqp...lkgeaikasvk
                          e+  EeDe E           LK  e  ++++ +++ + +s  
  gi|1087096   443 -------EVTVEEDEMEG----------LKQKEQKIsgkVVKKDLQNS-- 473  

                   eKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVe
                        KK +       d  +pF i+ P +  +l  Ll + +    + I++
  gi|1087096   474 -----KKESNAESQVKDDNLPFVIEAPSNLKDLCSLLDGWSETEIIEIIS 518  

                   RIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqL
                   RI++++++ L++eNRK+++v F+ vLLq+        ++++  +++ f L
  gi|1087096   519 RIRTCNSIRLAAENRKKMQV-FYGVLLQYF-------AVLATQSPVRFKL 560  

                   LekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSlk
                      Lv++Lie++ e P+++ai+++++l  ++ +l+e +k     ++PSlk
  gi|1087096   561 IDTLVKPLIEMSGETPYFAAICARQRLIHTRTRLCEDIKVSGKSCWPSLK 610  

                   dLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfL
                   +L++++L++l+F++SDfrH+V TP lllm+e+L+r+p++S++d+a G+fL
  gi|1087096   611 TLLLLRLWSLIFPCSDFRHVVATPMLLLMCEYLMRCPIQSGRDVAVGSFL 660  

                   vsiVLkfqsiSkRyvPeVvyalqqiLftll...........vpKRDVell
                   +s VL     Sk++ Pe v +lq  L t l+++ +++ ++++     el+
  gi|1087096   661 CSMVLVATKESKKFCPEAVVFLQSLLVTSLggnlgsdlrkkINDQFLELK 710  

                   sitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtite
                      P + +               + +v + ++le+      D       +
  gi|1087096   711 TMEPWLHIHE------------KVHEVNPANILEVICMD-SD------AP 741  

                   efpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrysl
                   +f++d +++S Ll+  v e + ++v i   l +F+EIflPI+ L + +  
  gi|1087096   742 YFSSDNFKASVLLS--VAECLRGFVIIHEELCSFPEIFLPISSLMQEIMD 789  

                   keslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePK
                   k  lp   l+  l  ++el+    ++ ++ r PL +++ KP  Ir l+PK
  gi|1087096   790 KSDLPGL-LQYILHEVIELIKNRSDEVHASRQPLQMRKQKPEPIRQLNPK 838  

                   FEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFv
                   FEEny      + + yDpD+eR++++K+k++lK EkKGA+RElRKD +F 
  gi|1087096   839 FEENY----IKGLD-YDPDRERAQMKKMKKRLKSEKKGAMRELRKDNYFL 883  

                   arlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   + ++ kE+ +++qer+EK +k+ ++lqeqe+A+   
  gi|1087096   884 SAVKEKERIKQEQERAEKYGKAMAFLQEQEHAF    916  

gi|168018956|ref|XP_001762011.1|: domain 1 of 1, from 25 to 927: score 608.0, E = 9.9e-180
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvK.geeG
                      ++  +              N F+   ++rKFd+lG+   k K+g+  
  gi|1680189    25    GPKTQGGH---------SENVFETLWTRRKFDVLGK---KQKgGDAK 59   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                    +G  R  a+ekRk+ l  e+k++ K++af+D R+GE +  L+     E+
  gi|1680189    60 RVGLARSAAVEKRKKSLLPEYKQRGKTNAFLDSRFGEHDESLG----DED 105  

                   KMleRfsRErmSQlrLSKreaynlnDGlEDve......edGdrggsSvKD
                   K + Rf+ Erm Q +  K++   l    +D+e++++  ++G   +s   D
  gi|1680189   106 KAILRFQKERMVQMQ--KKKKFALE--DDDDEqptellTHGGNALS-TFD 150  

                   DlDsleelgeeLsddd....ELadeaLDkdflalkrFeeeDAeaeeeqrG
                   D+        + +dd      L   +   d+   ++F + DA +ee ++G
  gi|1680189   151 DFKDDISIESDGDDDGcmffILHEIV--RDLHFGGGFVGKDA-GEEDGEG 197  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkd......L
                    k +KkE+meE+IaKSK+ Ka +aKeKee   l +kLD+ f    ++++L
  gi|1680189   198 KKRTKKEIMEEVIAKSKFFKAQKAKEKEEDHELKEKLDADFTAlaqssgL 247  

                   lsllamekltsRKsG...............iKkpreakedtDaeYDlllk
                   lsl+   k+ + Ks  +++ +++++  +  i   +  +e +D  YD+l+k
  gi|1680189   248 LSLVRPKKVDALKSMlskgasgsgsalkalIAGDQTLEEKPDE-YDKLVK 296  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEe
                   EM fe+R++ sdR KT EElA++E+e+L+ LE  R++RM +  E e  E+
  gi|1680189   297 EMGFEIRGHASDRSKTAEELAKEERERLEDLERKRKQRMLGGAESESDEA 346  

                   E..iGGEESv....kklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDN
                   E++   EES ++++kk + +S+dDL+  f  E++    G+ +++l R   
  gi|1680189   347 EsdQDEEESRrqqkKKRREISGDDLGENFVMEDEYQENGWVDEVLARKGD 396  

                   vdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAE
                    d e +dEd+de   ++dDdd+ +        +     d E +DD+   E
  gi|1680189   397 SD-EDEDEDEDEDEDEEDDDDGSSA-------RSEEDADSEGSDDE--DE 436  

                   LEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKAN
                    E  e  eD E  edE   a ++   +L     q l  + i a   +KA 
  gi|1680189   437 SEGSE-DEDWENSEDEL--AGIEGIPKLSAKD-QNLLDKLIAAK-TKKA- 480  

                   mKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIik
                    KK  +     Ld  +p+ id P t +++ +L+   + +D    VeRI+k
  gi|1680189   481 -KKPVSG-GNELDSALPYVIDAPQTLVDFRQLVDSRSIKDLEVAVERIRK 528  

                   ahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekL
                   ++ + L++eNRK+++v F+ vLLq+        +  +   +LN+q  + L
  gi|1680189   529 CNAISLAAENRKKMQV-FYNVLLQYF-------ATIAGERPLNLQRVNAL 570  

                   veaLielaqelPeklaislseellevikelaeeykknEhi.kyPSlkdLv
                   v++Liel+ e  + +a +++e++  + k+l e+    ++i+ +PS+ +L+
  gi|1680189   571 VKPLIELSGETHYYAAVCARERIIRMQKQLSEKLHSQDDIsSWPSNRTLL 620  

                   fFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsi
                   +F+L++ +F+ SDfrH+V+TPa+llm+e+L r+pv S+ d+a G f++s+
  gi|1680189   621 LFRLWSMIFPPSDFRHAVMTPAMLLMSEYLLRCPVKSGHDVAVGTFICSL 670  

                   VLkfqsiSkRyvPeVvyalqqiLftllvpK..RDVellsitPLtFerdRL
                    L   +  +R+ Pe   +lq  L+    pK +R  +l    P       +
  gi|1680189   671 LLSVMRPARRFCPEALSFLQALLL-SALPKmnRSKNLSLHCPSHLVEF-V 718  

                   Ds...lekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrs
                    s++ l++     +  +v  +  l    L +aD      +  f +d ++ 
  gi|1680189   719 ASkqwLQL---SSATSTVEGVQPLDFTSLLTAD----SSSSTFESDSFKV 761  

                   SlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRl
                    +L +  v+ +v ++ve+y    +F+E+f P+  LL ++ +   lpe  l
  gi|1680189   762 GILYS--VIKTVSGFVEVYSNIASFPEVFSPFASLLDALKNNNALPEA-L 808  

                   keklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKR
                         + + +  +  ++   r PL ++  KPv I + +P FEEny    
  gi|1680189   809 MVLTTEVSQFIAEKVKEHETTRLPLLMRMSKPVPIKTYNPQFEENY---- 854  

                   sPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEka
                   + + + yDpD+eR+e +KLk++lKrE+KGA RElRKD  F a +++kE a
  gi|1680189   855 VKGRD-YDPDRERAETKKLKKQLKREAKGAARELRKDNWFLAEEKAKENA 903  

                   akdqerhEKmkkivnelqeqegAl<-*
                      qer EK  k+  +lq qe A+   
  gi|1680189   904 VLQQEREEKYNKAMSFLQQQESAF    927  

gi|170091488|ref|XP_001876966.1|: domain 1 of 1, from 38 to 886: score 574.3, E = 1.4e-169
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        e +++K     +i+++ NPFd kv+k K d++Gr   + Kg  Gk
  gi|1700914    38    DKEKKAAK---LEEIKQRLNPFDTKVTKLKHDVGGR---RLKGITGK 78   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P  S++ ++e+Rk+Tl +e++ k + g++iD+R+GE+++  s     Ee 
  gi|1700914    79 PAKSKQAGIEQRKKTLLKEYEEKDRAGGIIDRRFGENDPTMS----IEER 124  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf+ Er  Q+  SK  a  +n  lED ee+++ g+s     +D +  
  gi|1700914   125 MLERFTKER--QRA-SKGAA--FN--LEDEEELTHYGQS--LSKMDDFDN 165  

                   lgeeLsdddE.....LadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKk
                    g + + d+E++ ++ + e   +  +++++F +e ++  e+ r  kKsK+
  gi|1700914   166 VGLGSDSDEEkglgqIDRET--VTKTHFGGFSDEEDSDGEPER--KKSKA 211  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   EVm E+IaKSK  K  r+ eK   eD + +LD Nf  L  l+    +   
  gi|1700914   212 EVMAEVIAKSKEHKLRRQMEKQAGEDVRHELDNNFAALRDLIYAPDPS-T 260  

                   KsG.............iKkpreakedt........DaeYDlllkEMvfek
                    sG++  + +++ +++ K p +  e ++   ++ +D+ YD  ++E+ f+k
  gi|1700914   261 SSGsnlvplgtraepsAKPPSDVNETLkvlapeaqDDDYDQHVRELAFDK 310  

                   RAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEE
                   RA+P dRTKTeEElA +E+e L++ E  R +RM + eE e  +e   G  
  gi|1700914   311 RAKPKDRTKTEEELALEEKESLEKAERARRRRMLGLEE-ESDDE---GKG 356  

                   SvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNe.EddEddd
                     k  + r++dDL D +  +ED    G + +l+   D  ++e+E+dE+ d
  gi|1700914   357 KGKGKRKRGADDLED-DFYDEDAELGGLGAGLEG-GDTLEAEqEEDEGQD 404  

                   eeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdE
                   +e e s +                       e D+     E  +  +D E
  gi|1700914   405 DEGESSGG-----------------------EEDE-----EEGS-ADDSE 425  

                   eDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPAS
                   e  +E                 + l+  a +a +  KA  +  ++     
  gi|1700914   426 EEQGEH----------------ENLVSVASSAKGESKA--RQLSSV---- 453  

                   LdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNR
                       +pFt++cP thee+l  + + + +D+p+IV+RI++++h  L++eN 
  gi|1700914   454 ---ELPFTFPCPSTHEEFLKIVDGVADADVPTIVQRIRTLYHTSLAPEN- 499  

                   KeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqel
                   K kl  + +vL  hI  L+   + +   +   f L + L ++Li +++  
  gi|1700914   500 KFKLQTLGAVLIDHI--LY--ITSLSEPS---FTLVSALLPHLIAITRAY 542  

                   Peklaislseellevikelaeeykk....nEhikyPSlkdLvfFkLvgll
                   P  +a ++ e+l  + k l      +   ++ + +P l  L +++++gl 
  gi|1700914   543 PIPAAECFNEKLTLMHKNLKRGLSRgalmPDSKTWPKLPELSLLRIIGLV 592  

                   FsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiS
                   ++TSD  H+V++P   l+  +L   +v+Sl+dIa GlfL+s++L+f   S
  gi|1700914   593 WPTSDLNHAVISPTRVLIGAYLGLGRVRSLSDIASGLFLCSLFLQFEALS 642  

                   kRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPld
                   kR+vPe  ++l   ++  l p    + +   P+ F  +  D  ++    +
  gi|1700914   643 KRLVPEAGNFLVNTVL-HLAP-HHYKDIPSLPGSFPSP--DFRSESCRRL 688  

                   nlfav..kestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleL
                    l+ +++k   + +p   sl       i+ +  + + ++ lL    + eL
  gi|1700914   689 MLKLNgkKAPVIQKPNLTSLLS-----ISQA--SEQAKTDLLGL--AFEL 729  

                   vEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlk...eklldav
                   +  + e y++  AFiE   PIl  L+       l e  l  +  kl d +
  gi|1700914   730 LGRFAELYKGIDAFIELYEPILVILQNVDA-DNLIEG-LRvqlAKLTDSL 777  

                   elveKltedakkerKPLAlqeHKPvaIrllePKFEE...nyDDKRsPdks
                   + + K+     + r PL lq HKP+ I++  PKFE +++ny     +   
  gi|1700914   778 QRLLKFSR---QARQPLRLQAHKPIPIPTYIPKFETtssNY-----LRRQ 819  

                   SyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqe
                     DpD e+ e +KL+ + K E+KGAiRElRKDa+F a +  k +  kd +
  gi|1700914   820 --DPDHEKNEAAKLRNQYKQERKGAIRELRKDARFLAGVEQKKQIEKDRA 867  

                   rhEKmkkivnelqeqegAl<-*
                   ++E mk++   +  +  ++   
  gi|1700914   868 YNERMKRVFGSIEGERAEE    886  

gi|91090988|ref|XP_974875.1|: domain 1 of 1, from 2 to 790: score 571.8, E = 7.6e-169
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k+  + eK           NPF+++ +k K  +lG    k K ++G 
  gi|9109098     2    KPRKKPEK--------NAPNPFEIHINKQKMTVLGQ---KNKNDRGL 37   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka+ kRk Tl +e+k  nKs+ f D+RiGEr   L+     E+K
  gi|9109098    38 PGVSRAKALKKRKETLLQEYKLQNKSNKFTDRRIGERSRDLT----SEDK 83   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    ++Rf++ r    +  K++  nl     D+e +++ g++     l ++e+
  gi|9109098    84 LMARFTALR---KKAHKKSIFNLA----DDEVLTHKGQT-----LAEIEK 121  

                   lgeeLsdddELadea...LDkdflalkrF.eeeDAeaeeeqrGAkKsKkE
                    ++ +sd +  + + +++LD  f   ++F++++     +e++   K+ +E
  gi|9109098   122 FDDPRSDNEDSDEDKsgkLDSAFVGDAHFgGGVLRKTGKEGA---KTHRE 168  

                   VmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRK
                    ++E Ia+SK +KaE++  Ke    l++kLD   kdLl+l++  +     
  gi|9109098   169 LIDELIAESKKRKAEKQRTKEATLELTEKLDTEWKDLLPLVS--RAQ--- 213  

                   sGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekL
                       k  + k   D+ YD+  +E+ fe R+ +sdR+K e+E Aq+E+ +L
  gi|9109098   214 ----KGEPDKGAVDD-YDKVMRELRFEARGTVSDRLKSEDEVAQEEKQRL 258  

                   reLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEED
                   +eLEe R +RM++ e               k  k+rS+dDLdD   V E 
  gi|9109098   259 EELEEKRRERMRGFEP--------------KTQKHRSADDLDD--DVYEA 292  

                   KPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKe
                    P +      +  E Nv+ + + ++   + e+sd ++             
  gi|9109098   293 DPEYMLSYNTEG-EANVEIGAEINGKTVGGEESDEEEECEE--------- 332  

                   avLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaq
                      ++ E++DDd    L D + e  dE De  E                 
  gi|9109098   333 ---EEEEQSDDD----LADLKAETSDESDEETE----------------- 358  

                   plkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlk
                       +a k  v  K+      +T       ++pFt+  P ++e+l +Ll 
  gi|9109098   359 ---AKATKTDVVAKT-----DET-----SADLPFTFALPDSYEALQQLLD 395  

                   kldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDls
                   + +  + ++I eR  k++hp L+e N K  l+ + v LLq++     D +
  gi|9109098   396 DKSSRQQATILERMVKCNHPSLAEKN-KNGLGTLFVYLLQYL----NDCA 440  

                   eQdikknLNfqLLekLveaLielaqelPeklaislseellevikelaeey
                      +     f+  + L ++ + laq++ e       +  levike+  e+
  gi|9109098   441 SEKSAAR-LFEIYKSLAPHIFDLAQLNKEN----THSSMLEVIKEKHDEF 485  

                   kknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspv
                   kk   +++P l+ LvfFkLv+llF TSDfrH VvTP++ ++ + L ++++
  gi|9109098   486 KKR-PKDFPGLELLVFFKLVSLLFTTSDFRHQVVTPCFVFIEQILNKCKI 534  

                   sSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVel
                    S+kdIa G fLv++VL++ s SkR +P  ++ l +iL+ + +pK  V+l
  gi|9109098   535 KSGKDIAYGIFLVTLVLEYTSLSKRVLPTAINYLGGILH-MAIPKCGVKL 583  

                   lsitPLtFerdRLDslekGLPldnlfavkestl.lepqrLslaDLVtqti
                   + + P +F      sl +     + +   +  +++e   L   D     i
  gi|9109098   584 IKVNP-PFKPT-TSSLVL-----VEKSCEDCDFkMEASDLE-RD----EI 621  

                   teefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsry
                      f+ +a  ++l l+      +   v    +l++  EIf  I a L ++
  gi|9109098   622 NDSFKIRAIYTVLRLV---QDFDNNLV----SLPSNVEIFNDIRAYLELL 664  

                   slkeslpekRlkeklldavelveK.ltedakkerKPLAlqeHKPvaIrll
                   +    +p k +    +++ + +  ++ e   ++     l+ ++P+a+rl 
  gi|9109098   665 PT-RNYPKK-VADLFESVSQQLKNrKVE---RKLEYIVLAAKRPKALRLY 709  

                   ePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDa
                   ePK  E++D K++   s     +e++e+ KL++klK+E KGA RE+R+D 
  gi|9109098   710 EPKIVEVFDGKKRKIQS-----REKAERDKLLHKLKKETKGALREIRRDK 754  

                   kFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    F  r+++ ++ ++d er EK+k+i++e++ q+ +l   
  gi|9109098   755 AFLGRVKIHQRIQSDNERKEKVKRIYAEASIQQSEL    790  

gi|114158701|ref|NP_083554.2|: domain 1 of 1, from 19 to 850: score 566.0, E = 4.3e-167
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1141587    19    GASGGPAK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|1141587    55 PGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1141587   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|1141587   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ l +  k++  
  gi|1141587   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMS-RKPK-- 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +D  YD  ++E+ fe  A+Ps R KTeEElA++E e+
  gi|1141587   236 KSEDKEKKE-KPQPDE-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQER 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L +LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|1141587   284 LKKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|1141587   318 -----GFILDKDD-----RRLLSYKDGKMNIEDVQEEQSKEADGQENDQK 357  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                          E eDD    E ED++  eD Ee ed  S + l+   +  e+  
  gi|1141587   358 -------EGEDDS---EEEDES-HEDSEESEDPDSHSDLESNIESEEENE 396  

                   qplk.......geaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                    p k+++++++g+ +k     KA   K            +p+ +  P ++
  gi|1141587   397 TPKKeqrqtpgGKLPKDD--QKA--QKAVAA-------ELPYVFAAPESF 435  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   eel  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I
  gi|1141587   436 EELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI 484  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                        Dl+         +    kLv +L++l q +Pe +  s + +l++ 
  gi|1141587   485 ----GDLATDSTPD---LKTIDKLVVHLYSLCQMFPESASDSIRFVLRDA 527  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                     e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPall m+
  gi|1141587   528 MHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALLCMS 577  

                   evLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   + L ++pv Sl+d+ +Glf + ++L+++s S+R++Pe++++l +iL+   
  gi|1141587   578 QMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGILY-IA 626  

                   vpKRDVells....itPLtFerdRLDslekGLPldnlfavkestllepqr
                    p    + +s++++++  +F     +  ++   l+++  + ++t      
  gi|1141587   627 TP----NTKSqgstLVH-PFRAL--GKNSE---LLVVSDKADVTTWQRGS 666  

                   LslaD...LVtqtiteefpvda.lrsSlLliKEvleLvEeiveiyyklqA
                   L+l   ++L t t te+  +++++++S L+           v  y  l++
  gi|1141587   667 LPLHWanrLSTLTATEANHTRLsCVASCLSL------MKHCVLMYQALPS 710  

                   FiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKP
                   F  If P +aLLs+     slp+      l   ++ +    e  k+   P
  gi|1141587   711 FHAIFRPHQALLSKHLADCSLPQE-----LQELAQSILSAMEGQKQHCRP 755  

                   LAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklK
                   L   + KPv +    P+   + +  R  + s     ke  e++ L +k+K
  gi|1141587   756 LVCEKSKPVPLKQFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHK 800  

                   rEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl
                   rE KGA+RE+RKD +F ar  l E    d er  K+k + n l +qeg+ 
  gi|1141587   801 REFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW 850  

                   <-*
                      
  gi|1141587     -     -    

gi|148705517|gb|EDL37464.1|: domain 1 of 1, from 27 to 858: score 566.0, E = 4.3e-167
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1487055    27    GASGGPAK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 62   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|1487055    63 PGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNIS----PEEK 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1487055   109 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 147  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|1487055   148 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 196  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ l +  k++  
  gi|1487055   197 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMS-RKPK-- 243  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +D  YD  ++E+ fe  A+Ps R KTeEElA++E e+
  gi|1487055   244 KSEDKEKKE-KPQPDE-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQER 291  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L +LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|1487055   292 LKKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 325  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|1487055   326 -----GFILDKDD-----RRLLSYKDGKMNIEDVQEEQSKEADGQENDQK 365  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                          E eDD    E ED++  eD Ee ed  S + l+   +  e+  
  gi|1487055   366 -------EGEDDS---EEEDES-HEDSEESEDPDSHSDLESNIESEEENE 404  

                   qplk.......geaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                    p k+++++++g+ +k     KA   K            +p+ +  P ++
  gi|1487055   405 TPKKeqrqtpgGKLPKDD--QKA--QKAVAA-------ELPYVFAAPESF 443  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   eel  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I
  gi|1487055   444 EELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI 492  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                        Dl+         +    kLv +L++l q +Pe +  s + +l++ 
  gi|1487055   493 ----GDLATDSTPD---LKTIDKLVVHLYSLCQMFPESASDSIRFVLRDA 535  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                     e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPall m+
  gi|1487055   536 MHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALLCMS 585  

                   evLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   + L ++pv Sl+d+ +Glf + ++L+++s S+R++Pe++++l +iL+   
  gi|1487055   586 QMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGILY-IA 634  

                   vpKRDVells....itPLtFerdRLDslekGLPldnlfavkestllepqr
                    p    + +s++++++  +F     +  ++   l+++  + ++t      
  gi|1487055   635 TP----NTKSqgstLVH-PFRAL--GKNSE---LLVVSDKADVTTWQRGS 674  

                   LslaD...LVtqtiteefpvda.lrsSlLliKEvleLvEeiveiyyklqA
                   L+l   ++L t t te+  +++++++S L+           v  y  l++
  gi|1487055   675 LPLHWanrLSTLTATEANHTRLsCVASCLSL------MKHCVLMYQALPS 718  

                   FiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKP
                   F  If P +aLLs+     slp+      l   ++ +    e  k+   P
  gi|1487055   719 FHAIFRPHQALLSKHLADCSLPQE-----LQELAQSILSAMEGQKQHCRP 763  

                   LAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklK
                   L   + KPv +    P+   + +  R  + s     ke  e++ L +k+K
  gi|1487055   764 LVCEKSKPVPLKQFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHK 808  

                   rEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl
                   rE KGA+RE+RKD +F ar  l E    d er  K+k + n l +qeg+ 
  gi|1487055   809 REFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW 858  

                   <-*
                      
  gi|1487055     -     -    

gi|70983404|ref|XP_747229.1|: domain 1 of 1, from 37 to 898: score 564.5, E = 1.2e-166
                   *->keedreeKKKAvakiqkefNPFdvkva.krKFdilGrsKtkvKgeeG
                      +   r+    A + i+ +fNPF++kv++++KFd+  r     K + G
  gi|7098340    37    SAQNRAQRNAALQAIRDRFNPFEIKVTsRNKFDVTTR-DGGSKPAAG 82   

                   k..PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                    ++PGV +  +eekR++Tl  e + knK g+++D+R+GE ++  +     
  gi|7098340    83 LsrPGVTKSLGEEKRRQTLLREMERKNKIGGIVDRRFGEDDPTMT----P 128  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKDDl.
                   Ee   +Rf RE   Q +L K ++ nl D  ED+  +++ g++    DD +
  gi|7098340   129 EERAAARFARES--QKKLRKESMFNLEDDDEDDFQLTHKGQTlTLGDDVp 176  

                   .DsleelgeeLsdddELadea.......LDkdflalkrFeeeDAeaeeeq
                   +D +ee   +L ++d  ++e+++++++ LD d l    F +eD e + e+
  gi|7098340   177 qDDFEEDLRGL-EEDQSDSEVprkrkriLDNDELEDFVFDDEDGEDQPER 225  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll
                   +   KsK EVm+E+IaKSK+yK Er+K+Kee   l+++LD+   dL   l
  gi|7098340   226 K---KSKHEVMKEVIAKSKFYKLERQKAKEEDDELREELDKGLPDLFDML 272  

                   amekltsRKsGiKkpre.............akedtDaeYDlllkEMvfek
                      k+  +    K+  e+ ++++    +++a  d+ +eYD  lk + f+k
  gi|7098340   273 RGVKPPPKPEPAKDDLEsmnpdraallkgtADNDPNKEYDQRLKQLTFDK 322  

                   RAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEE
                   R +P+dRTKT EE+A +Ea +L  LEeeRl+RM++ +E +d+Ee+    E
  gi|7098340   323 RSQPTDRTKTAEEKAEEEAQRLKTLEEERLRRMRGEQE-SDEEEDDEEGE 371  

                   SvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEddde
                   S       +++D  D  s+ +D   fG  +   +   N   e   Ed+d+
  gi|7098340   372 SE-----TGGEDSND-ESIPDDAEAFGLKQPSPQ--TNKGPEMGVEDEDD 413  

                   eaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEe
                    + d d  +  +            L  dE +  +        + ee  Ee
  gi|7098340   414 FIIDDDLVETRSN---------VSLSFDESDGEE------GSS-EEKSEE 447  

                   DedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASL
                    + EE         +L +    p  +++ +      A   K ++      
  gi|7098340   448 EDEEE--------DELINGLTLPTSKSGESTAAADGA--GKRSEG----- 482  

                   drsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRK
                      +++t++cP  he +le +k+    D p++++RI+ +hhp L+++N K
  gi|7098340   483 ---LAYTYPCPEDHESFLEVIKDVPMNDLPTVIQRIRALHHPRLHADN-K 528  

                   eklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelP
                    kl+ F +vL +h+   +  ++eQ+   +  f  Le    + ++la++ P
  gi|7098340   529 TKLGRFAAVLVRHV--AY--MAEQPEHPP--FNVLEAILRHIHSLAKSHP 572  

                   eklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSD
                   e        ++  +++ l e +    h   +  +dLv +  ++  F+TSD
  gi|7098340   573 ES-------VCMAYRNYLRE-IATD-HPLSLRAGDLVILTGIATTFPTSD 613  

                   frHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvP
                     H++ TPa l +a +L +  ++Sl d a G++ +s+ L++q iSkRy P
  gi|7098340   614 HFHAIATPAYLCLARYLGQGAINSLGDYATGAYAASLCLQYQTISKRYMP 663  

                   eVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfav
                   e ++ +  +L   l p      l   P    +    sl +          
  gi|7098340   664 EFINYVLNALC-NLCPTEPTSSLGFFPARGSQE---SLRL---------- 699  

                   kestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeivei
                    +s  l p +L   D +    +     d l+ Sl      + L+  +++ 
  gi|7098340   700 IPSKQLNPRKLRFWD-IATAQSDQRAQDELKLSLIHT--FVTLLNSASDL 746  

                   yyklqAFiEIflPIlaLLsry..slkeslpekRlkeklldavelveKlte
                   + + +AF EIf  ++  L   ++s k +l ++ ++  l +++ ++     
  gi|7098340   747 WAGKSAFFEIFEQVQRVLRHVskSAKGKLSST-VQDTLQSTLDKLDTHLS 795  

                   dakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRsel
                    a++ r PL l +H+P+aI +  PKFEE +    +Pdk  yDp +eR+el
  gi|7098340   796 RARATRRPLLLHNHRPLAIKTAIPKFEETF----NPDKH-YDPNRERAEL 840  

                   nKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivne
                   n Lka  KrE+KGA+RElRKDa F+ar++l Ek   d e+  K k++v+e
  gi|7098340   841 NRLKAEFKRERKGAMRELRKDANFIAREKLREKKERDAEYEKKYKRLVAE 890  

                   lqeqegAl<-*
                   +q +eg +   
  gi|7098340   891 IQNEEGRE    898  

gi|118090714|ref|XP_420824.2|: domain 1 of 1, from 14 to 868: score 562.4, E = 5.3e-166
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++ ++ +    +a +++  NPF+vkv++ KF ilGr   k K ++G 
  gi|1180907    14    SSKAKGSAEPTIAMVKS--NPFEVKVNRQKFNILGR---KTKNDVGL 55   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka+ kR +Tl +e+k k K+++f DkR+GE n   s     EeK
  gi|1180907    56 PGVSRSKAIKKRTQTLLKEYKEKEKTNVFRDKRFGEYNTKIS----PEEK 101  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf+ Er  Q    K++ ynln     +ee+++ g+s     l ++e+
  gi|1180907   102 MIKRFTLER--QQNYGKKNIYNLN----EDEELTHFGQS-----LAEIEK 140  

                   lgeeLsdddELade.aLDkdflalkrFeeeD........AeaeeeqrGAk
                   l +  + d   +  +aL + ++a+ +F++ ++  +++ + e e+e +   
  gi|1180907   141 LNDVIDSDSDTDERgALSAELTAA-HFGGGGgllrkkasTEQEDEEEEKP 189  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K+Er+  +e    l++kLD   k ++ l a  k
  gi|1180907   190 KSRKELIEELIAKSKQEKQERQSRRESALELTEKLDNDWKEIQTLMA-RK 238  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +   Ks  K+    k+ +D  YD  ++E+ fe  A+Ps+R KTeEElA++
  gi|1180907   239 PP--KSERKDKEAEKPKPDE-YDMIVRELGFEMKAKPSERMKTEEELAKE 285  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E+++L +LE  Rl+RM++ +E   +          kk+ + S+dDL D  
  gi|1180907   286 EEARLQKLEADRLRRMRGIGE--QENK--------KKPSHVSADDLTD-- 323  

                   sVEEDKPKfGfied.....lleRED...NvdNeEddEdddeeaedsdDdd
                            Gfi+d+++++ll   D++ N++N E+ Ed  ee   ++ ++
  gi|1180907   324 ---------GFILDkddrrLLSYKDgkmNIENVEEEEDKEEEEDKEEEEE 364  

                   svndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaE
                    +               + E+eD +       +e  e++   edEE D  
  gi|1180907   365 QEEE-------------EGEKEDNE------NEE-GEEESATEDEE-DVA 393  

                   ldvlkdLKedeaqplkgeaikasvkeKANmK..........KsadTiPAS
                    d+++dL  d    +   + k   k KAN  ++++ ++ ++K+       
  gi|1180907   394 SDNHSDLESDLESEEEAAGNKEQKKHKANENesqnveeldpKMEAA---- 439  

                   LdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNR
                       +p+t+  P ++e +  Ll +   e+  +I eRI k++hp L+ +N 
  gi|1180907   440 -KSELPYTFAVPESYEKFKSLLAGRTVEQQLTILERIQKCNHPSLAVGN- 487  

                   KeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqel
                   K kl+K+  + L +I     +l+ +d  +   +    kL  +L+ l q +
  gi|1180907   488 KTKLEKLFGFILEYI----GELATLDLPE---LKTIDKLILPLYNLCQMF 530  

                   Peklaislseellevikelaeey.kknEhikyPSlkdLvfFkLvgllFsT
                   Pe++      +l++   e+ e +++k     +P l++L+++k+++llF+T
  gi|1180907   531 PEAASGNIKFVLRDAAHEMEEVIeVKG-RATFPGLGTLIYLKITSLLFPT 579  

                   SDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRy
                   SDf H+VvTPa++ m++ L ++++ +l+d+ +Glf++s+ L+++s SkR+
  gi|1180907   580 SDFWHPVVTPAFIYMSQLLTKCRITTLQDVIKGLFICSLLLEYVSLSKRF 629  

                   vPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlf
                   vPe++++l + L+  + pK+      ++  +F         k L l+ + 
  gi|1180907   630 VPELINFLLGVLH-ISLPKKQAQGYTVVH-PFTPV-----GKNLELLLVC 672  

                   avkestllepqrLslaDLVtqtiteefp...vdalrsSlLliKEvleLvE
                    +k++   + q+L+   L   t + e+++++    r S L       L+ 
  gi|1180907   673 DKKDLESWKKQNLP---LSVVTRLKELSkteINHIRLSCLAL--CFDLIK 717  

                   eiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveK
                        y +l++F EI+ PI  LL +  +  ++pe  ++e    a++ +e 
  gi|1180907   718 RCAVLYESLPSFYEIMHPIRVLLTQRVSVSEYPEQ-MQEWYHGALKELEN 766  

                   ltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeR
                   +t        PL   ++KPv +    PK   + +  R  + s     k  
  gi|1180907   767 KTK----HYTPLICEKKKPVPLKQYTPKIVKVLEFGRKQGGS-----KKE 807  

                   selnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkki
                    e++ L +k+KrE KGA+RE+RKD +F ar  l E    d++r  K+k +
  gi|1180907   808 QERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDSARKRKVKEL 857  

                   vnelqeqegAl<-*
                      l +qeg+    
  gi|1180907   858 LGSLATQEGEW    868  

gi|149047414|gb|EDM00084.1|: domain 1 of 1, from 19 to 852: score 557.2, E = 2e-164
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +      K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1490474    19    GAFGGPGK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|1490474    55 PGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1490474   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|1490474   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ ll+    +s+
  gi|1490474   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILLS---RKSK 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +Da YD  ++E+ fe  A+Ps R KTeEElA++E ek
  gi|1490474   236 KSENKEKKE-KPQPDA-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQEK 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   Lr+LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|1490474   284 LRKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|1490474   318 -----GFILDKDD-----RRLLSYKDGKMNIEDAQEEQSKGADGQENDQK 357  

                   eavLkddEneDDdLGAELEDkeGeeDdEeD.....edEESDaEldvlkdL
                   e   +  E+  D        ++ e+ dE D++++++d ES aE +   + 
  gi|1490474   358 EEEDESEEEGEDG-------ESCEDPDESDgpdshSDLESSAETEEEDET 400  

                   .KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                   +K +  q   g+ +k     KA   K a          +p+ +  P ++e
  gi|1490474   401 pKKEQRQTPGGKSPKEA--QKA--QKAAAA-------ELPYVFAAPESFE 439  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                   el  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I 
  gi|1490474   440 ELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI- 487  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                       Dl+         +    kLv +L+ l q +Pe +    + +l++  
  gi|1490474   488 ---GDLATDSTPD---LKTIDKLVVHLYNLCQMFPESASDAIRFVLRDAM 531  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                    e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPal+ m++
  gi|1490474   532 HEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQ 581  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                    L ++pv Sl+d+ +Glf + ++L+++s S+R+vPe+ ++l +iL+    
  gi|1490474   582 MLTKCPVTSLRDVVKGLFVCCLFLEYVSLSRRFVPELLNFLLGILY-IAT 630  

                   pKRDVells....itPLtFerdRLDslekGLPldnlfavkestl.....l
                   p    + +s++++++  +F     +  ++   l+++  + ++t  ++++l
  gi|1490474   631 P----NKKSqgstLVH-PFRAL--GKNSE---LLVVSDKADVTTwqrgsL 670  

                   epqrLslaDLVtqtiteefpvda.lrsSlLliKEvleLvEeiveiyyklq
                   +++        t t te+  +++++++S L+       +   v  y  l+
  gi|1490474   671 PLHWANRQS--TLTATEANHTRLsCVASCLSL------LKHCVLMYSALP 712  

                   AFiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerK
                   +F  I  P +aLL       slp+  l+e   + +  ve    + k+   
  gi|1490474   713 SFHAIVTPHQALLAEHLA-RSLPQE-LQELSRSILSEVE----SQKQHCP 756  

                   PLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkakl
                   PL   + KPv +    P+   + +  R  + s     ke  e++ L +k+
  gi|1490474   757 PLICEKSKPVPLKQFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKH 801  

                   KrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegA
                   KrE KGA+RE+RKD +F ar  l E    d er  K+k + n l +qeg+
  gi|1490474   802 KREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGE 851  

                   l<-*
                       
  gi|1490474   852 W    852  

gi|115490987|ref|XP_001210121.1|: domain 1 of 1, from 37 to 898: score 556.6, E = 2.8e-164
                   *->keedreeKKKAvakiqkefNPFdvk..vakrKFdilGrsKtkvKgee
                          r     A + i+ +fNPF++k++++krKFd+  r   k    +
  gi|1154909    37    AAQNRNQRNAALQAIRDRFNPFEIKttATKRKFDVTTRDAGKEATVR 83   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV +  +eekR++Tl  e+ ++nK g++ D+R+GE ++  +     E
  gi|1154909    84 ARPGVTKSLGEEKRRQTLLRELHMRNKVGGIHDRRFGEDDPNMT----PE 129  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDve.edGdrggsSvKDDl..
                   eK  eRf RE   Q+++ K ++ nl D  +D e  +++ g++     l+ 
  gi|1154909   130 EKAAERFARES--QRKMRKDSMFNLEDDDDDEEfQLTHKGQT-----Lsf 172  

                   .Dsleelge.eLsdddELadeaLDkdfl.alkrFeeeDA.........ea
                   +D++ + +++e++++d + d+  D  fl+  krF +eD+++ ++++++e+
  gi|1154909   173 gDGMPQDDFeERDLGDAEEDDMSDSEFLrKRKRFDGEDDgeleendgpEG 222  

                   eeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdL
                   e+e +  kKsK EVm+E+IaKSK+yK Er+K+Ke    l+++LD+   dL
  gi|1154909   223 EDEPE-RKKSKHEVMKEVIAKSKFYKYERQKAKEDDDELREELDKGLPDL 271  

                   lsllamekltsRKsGiKkpreakedt...................DaeYD
                      l   k+        kp ++k d+ + ++++    ++++++++ +eYD
  gi|1154909   272 FDMLRGVKPP------PKPEPPKDDLasmnpdraallegksrddqEKEYD 315  

                   lllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEle
                     lk + f+kR +P+dRTKT EE+A +Ea +L +LEeeRl+RM++ eEl+
  gi|1154909   316 QRLKQLTFDKRSAPTDRTKTAEEKAEEEAQRLKKLEEERLRRMRG-EELS 364  

                   dgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP..KfGfiedlleREDN
                   ++Ee              S++D+    s +E  P++ + f++   +  D 
  gi|1154909   365 EEEE------------EESGEDEASEMSEDESIPddARAFGL--QQAADQ 400  

                   ........vdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEn
                   + ++++ +v+ e d+  dd++ e   D   v++                 
  gi|1154909   401 danrpelgVEDEDDFIIDDDLVETRSD---VSL----------------- 430  

                   eDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL...Kedeaqplkge
                   + D+   ++   e ee+ Ee e EE   El +   L+ +K+ ea      
  gi|1154909   431 SIDE--SDIVMSE-EEESEEEEQEE-EDELINGLTLpagKDGEASAAADN 476  

                   aikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldle
                   a  +                      +++t++cP +h+e+l+ + +    
  gi|1154909   477 ADGGN-------------------EELAYTYPCPGSHDEFLQIIDGVPMQ 507  

                   DkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdik
                   D p++++RI+ +hhp L+++N K kl+ F ++L +h+   +  ++eQ+  
  gi|1154909   508 DLPTVIQRIRALHHPRLHADN-KTKLGRFAAILVKHV--VY--MTEQPEH 552  

                   knLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknEh
                    +  f   e +  + ++la+  Pe      s+  +    e+a e   +  
  gi|1154909   553 PP--FAIVENTLRHIHSLAKTHPES----VSQAFRAHLREMARE--RP-- 592  

                   ikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkd
                     ++  +dLv +  v+ +F+TSD  H++ TPa l +a +L +  +++l d
  gi|1154909   593 -LALRPSDLVILTGVAAIFPTSDHFHAIATPAHLCIARYLGQGAINTLAD 641  

                   IaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitP
                    a G + +s++L++q  SkRy Pe ++ +  +L   l p   V+l+s   
  gi|1154909   642 FATGVYAASLFLQYQTMSKRYMPEFMNYILNALC-NLAP---VKLKSSLG 687  

                   LtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpv
                   L   r   D+l +          ++s +l p +L   D V    + +   
  gi|1154909   688 LFPSRTPQDPLRL----------QPSKKLSPRKLRFWD-VAGPASNA-EA 725  

                   dalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLL.sryslkes
                     l+ Sl     +++L+ ++++ +   +AF EIf P +  L++++ + e 
  gi|1154909   726 AELKLSLVTT--MVNLLDTASDLWADKSAFTEIFEPAQNVLrHLLQSCEG 773  

                   lpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE
                     +  +   + +++ ++      a+k r PL l +H+P+aI +  PKFEE
  gi|1154909   774 KVSSTVTDSIQSTLDKIDQHLSNARKTRRPLLLHNHRPLAIKSAIPKFEE 823  

                   nyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarl
                    +    +Pdk  yDp +eR+e n Lk  lKrE+KGA+RElRKDa F+ar+
  gi|1154909   824 SF----NPDKH-YDPNRERAEANRLKTELKRERKGAMRELRKDANFIARE 868  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    l Ek   d e+  K k++v+e+q qeg +   
  gi|1154909   869 QLREKKERDAEYERKYKRLVAEVQNQEGRE    898  

gi|121719657|ref|XP_001276527.1|: domain 1 of 1, from 37 to 898: score 555.9, E = 4.7e-164
                   *->keedreeKKKAvakiqkefNPFdvkva.krKFdilGrsK.tkvKgee
                      +   r     A + i+ +fNPF++kva++ KFd+  r  + k   ++
  gi|1217196    37    GAQNRLQRNAALQAIRDRFNPFEIKVAsRSKFDVTTRDVgSKTTAAR 83   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV +  +eekR++Tl  e + knK g+++D+R+GE ++  +     E
  gi|1217196    84 SRPGVTKSMGEEKRRQTLLREMERKNKVGGIVDRRFGEDDPTMT----PE 129  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs......SvK
                   e   eRf RE   Q +L K ++ nl + +ED+  ++++g+s + ++++++
  gi|1217196   130 ERAAERFARES--QKKLRKESMFNLEEDEEDDFKLTHMGQSlsfgdgAIQ 177  

                   DDlD....sleelge...........eLsdddELadeaLDkdflalkrFe
                   DD+ ++ ++lee ++++++++++++++ ++d+EL d              
  gi|1217196   178 DDFQddvgGLEEEDQsdsesprkrkrDMDEDEELEDYT-----------Y 216  

                   eeDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLD
                   ++D e+e+  +  kKsK EVm+E+IaKSK+yK Er+K+Kee  Dl+++LD
  gi|1217196   217 DDDEEGEDQPE-RKKSKNEVMKEVIAKSKFYKLERQKAKEEDDDLREELD 265  

                   eNfkdLlsllamekltsRKsGiKkprea.............kedtDaeYD
                   +   dL   l   k  ++    K+  ea ++++    ++++k+d   eYD
  gi|1217196   266 KGLSDLFDMLRGVKAPAKPEPAKDDLEAmnperaallkgesKPDAEREYD 315  

                   lllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeete...
                     lk + f+kR +P+dRTKTeEE+A +Ea +L +LEeeRl+RM++ + ++
  gi|1217196   316 QRLKQLTFDKRSQPTDRTKTEEEKAEEEALRLKALEEERLRRMRGEQlsd 365  

                   EledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleR..
                   E ed+Ee              S +   D  s+ +D   fG  +   e ++
  gi|1217196   366 EEEDEEE-----------DSESEEGSED-ESIPDDAMAFGLQQPTAETsg 403  

                   ..EDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDD
                   ++E  v+ e d+  dd++ e   D   v++                 + D
  gi|1217196   404 rpELGVEDEDDFIIDDDLVETRSD---VSL-----------------SFD 433  

                   dLGAELEDkeGeeD.dEeDedEESDaEldvlkdLKedeaqplkgeaikas
                   +   E E  + e+++dE De EE         +L +    p  + + +a 
  gi|1217196   434 E--SEGEEGSSEVEsDESDEEEE--------DELINGFTLPQDKAGASAA 473  

                   vkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplI
                     e +         P S +  +++t++cP  he++le + +    D p +
  gi|1217196   474 --EGT---------PQS-NEELAYTYPCPSDHEAFLEIVRDVPMNDLPVV 511  

                   VeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNf
                   V+RI+ +hhp L+++N K kl+ F ++L qh+   +  l+eQ+   +  f
  gi|1217196   512 VQRIRALHHPRLHADN-KMKLGRFAAILVQHV--AY--LAEQPEHPP--F 554  

                   qLLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPS
                     Le    + ++la++ Pe      ++ l+e+  e     +         
  gi|1217196   555 SILENIFRHVHSLAKSHPENVCMAYRSHLREMSTERPLGLRSG------- 597  

                   lkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGl
                     dLv +  ++  F+TSD  H++vTPa l +a +L +  v+Sl + a G+
  gi|1217196   598 --DLVILTGIATTFPTSDHFHAIVTPAHLCLARFLGQGAVDSLVEYATGA 645  

                   fLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFer
                   + +s++L++q  SkRy Pe ++ +  +L  l+ +    e +s   L  +r
  gi|1217196   646 YAASLFLQYQTVSKRYMPEFMNYVLNALCNLSPE----EPKSSLGLFPAR 691  

                   dRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrs
                               +     ++s  l + +L+  D +    +  +    l+ 
  gi|1217196   692 G----------AQEALRLTPSKQLSLRKLQFWD-MADAPSDQHAQEELKL 730  

                   SlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpek
                   Sl +    + L+  +++ +   +AF EIf P +  L   +++ k +lp  
  gi|1217196   731 SLVNT--FVTLLYSASDLWANKSAFWEIFSPAQRVLRHVskTCKGKLPLA 778  

                   RlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDD
                    ++ +l  ++  +    + a+  r PL l  H+P+aI +  PKFEE +  
  gi|1217196   779 -VQDNLQATLDQLDSHLARARLARRPLLLHHHRPLAIKTAIPKFEETF-- 825  

                   KRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkE
                     +Pdk  yDp +eR+eln Lka  KrE+KGA+RElRKDa Fvar++l E
  gi|1217196   826 --NPDKH-YDPNRERAELNRLKAEFKRERKGAMRELRKDANFVAREKLRE 872  

                   kaakdqerhEKmkkivnelqeqegAl<-*
                   k   d e+  K k++v+e+q +eg +   
  gi|1217196   873 KKERDAEYEKKYKRLVAEIQSEEGRE    898  

gi|56404627|sp|Q8R3N1.1|NOP14_MOUSE: domain 1 of 1, from 19 to 850: score 554.8, E = 1e-163
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|5640462    19    GASGGPAK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|5640462    55 PGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|5640462   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|5640462   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ l +  k++  
  gi|5640462   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMS-RKPK-- 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +D  YD  ++E+ fe  A+Ps R KTeEElA++E e+
  gi|5640462   236 KSENKEKKE-KPQPDE-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQER 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L +LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|5640462   284 LKKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+              d dd  +    d+     d   + q K
  gi|5640462   318 -----GFIL--------------DKDDRRLLSYKDGKMNIED-VQEEQSK 347  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaE.ldvlkdLKede
                   ea    d +e D    E ED++ ee+dE  ed E  +E+ d ++dL    
  gi|5640462   348 EA----DGQENDQ--KEGEDES-EEEDESHEDSE-ESEdPDSHSDLESNI 389  

                   aqplkgeaikasvk...........eKANmKKsadTiPASLdrsipFtid
                      +  e +k +  ++++++ ++++ KA   K            +p+ + 
  gi|5640462   390 ESEEENETPKKEQRqtpggklpkddQKA--QKAVAA-------ELPYVFA 430  

                   cPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvv
                    P ++eel  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +
  gi|5640462   431 APESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGF 479  

                   LLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislse
                   LLq+I DL       d+     +    kLv +L++l q +Pe +  sl+ 
  gi|5640462   480 LLQYIGDLA-----IDSTPD--LKTIDKLVMHLYSLCQMFPESASDSLRF 522  

                   ellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPa
                   +l++   e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPa
  gi|5640462   523 VLRDAMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPA 572  

                   lllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqi
                   ll m++ L ++pv Sl+d+ +Glf + ++L+++s S+R++Pe++++l +i
  gi|5640462   573 LLCMSQMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGI 622  

                   LftllvpKRDVells....itPLtFerdRLDslekGLPldnlfavkestl
                   L+    p    + +s++++++  +F     +  ++   l+++  + ++  
  gi|5640462   623 LY-IATP----NTKSqgstLVH-PFRAL--GKNSE---LLVVSDKADVAT 661  

                   lepqrLslaD...LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyy
                        L+l   ++L t t te+  +++   S       l+L    v  y 
  gi|5640462   662 WQRGSLPLHWanrLSTLTATEANHTRL---SCVAL--CLSLMKHCVLMYQ 706  

                   klqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakk
                    l++F  I  P +aLL +     slp+      l+  ++ +    e  k+
  gi|5640462   707 ALPSFHAIVRPHQALLAKHLADCSLPQE-----LKELAQSILSAMEGLKQ 751  

                   erKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLk
                      PL   + KPv +    P+   + +  R  + s     ke  e++ L 
  gi|5640462   752 HCRPLVCEKSKPVPLKQFTPRLVKVLEFGRKQGSS-----KEEQERKRLI 796  

                   aklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeq
                   +k+KrE KGA+RE+RKD +F ar  l E    d er  K+k + n l +q
  gi|5640462   797 HKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQ 846  

                   egAl<-*
                   eg+    
  gi|5640462   847 EGEW    850  

gi|156554877|ref|XP_001606853.1|: domain 1 of 1, from 13 to 897: score 552.3, E = 5.7e-163
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       ++++  K    + ++k   PF+v+v++ K ++lGr   k K + G 
  gi|1565548    13    DSYAKRRK---QQQTKKTLTPFEVHVNRDKQKVLGR---KSKADTGL 53   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+ R+ka+ kRk+Tl  e+k++ K + f+D+RiGErn   +     E+K
  gi|1565548    54 PGIARTKAIAKRKNTLLNEYKVRDKDNIFLDRRIGERNSGMT----QEDK 99   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    ++Rf +Er   ++ +  + + +n  l+D e +++rg+s     l  +e+
  gi|1565548   100 AMARFAAER---VK-AHSKKNIFN--LNDEEVLTHRGQS-----LMDIEK 138  

                   lgeeLsdddELadea.....LDkdflalkrFeeeDAeaeeeqrGAkKsKk
                   +++ +sd+d   d+++++++LDk f   ++F++   +  +       s k
  gi|1565548   139 YDDPRSDEDDYSDDEnktgkLDKKFVGDAHFGGGVLSKPDSEM----SRK 184  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                     +e  I++SK +KaEr+K +e   Dl++kLD    dLl+l+a   ++  
  gi|1565548   185 DLIEQLIVESKKRKAERQKVREQTIDLTEKLDSEWRDLLPLVASSNKA-- 232  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                        k+ e + +  + YD+  +E+ fe R+ P+d++K eE +A++E+ k
  gi|1565548   233 ----LKEVELEKPKADDYDIAMRELKFEARGMPTDKLKPEEQIAKEEKIK 278  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L++LEe Rl RM++  E e++             k+ S+dDLdD      
  gi|1565548   279 LEKLEEDRLARMKGFSE-EAEFQ----------RKHKSADDLDD------ 311  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                          ie + +  +  dNe d  d  +  +              k k 
  gi|1565548   312 -----FHIERIVD--EGSDNENDAPDLQSILAKHKN----------KIKN 344  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                       + d  + D+ G E ED+e  e+dE  e+EE     d l+dLKe+e+
  gi|1565548   345 NENIEADDRDEDEEGEEDEDEE-AEEDENEEGEE-----DDLSDLKESES 388  

                   .....qpl......kgeaik..asvkeKANmKKsadT.............
                   +++++++++++ ++k++a k+++ v +K+   K ++ ++  +++++++++
  gi|1565548   389 sedeeEIEntdindKEKATKrdNIVHKKTESVKDSSVksvanddstkgqk 438  

                   ............................iPASLdrsipFtidcPktheel
                   ++   ++++ +++++++++  + ++++ i       +p+t++ P t+eel
  gi|1565548   439 spvivntetvdestentesyvnieereaIMEKARQELPYTFKAPATYEEL 488  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                   l+L k+   +  + IVeRI k++h KL+e N Kekl ++ + L q++   
  gi|1565548   489 LDLFKDKNPDYQAVIVERIVKCNHWKLAERN-KEKLLNLFSYLMQYL--- 534  

                   fEDlseQdikknLN..fqLLekLveaLielaqelPeklaislseellevi
                    + l+  +++k   + f  + +L ++L+ l+q +P          l e+ 
  gi|1565548   535 -DTLASVNSLKDTEkfFKIFDRLCPHLYDLTQANPVG----TKIHLQEIL 579  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                   k++  ++ +n  + yP l++L++FkLv+++++TSDfrH++vTP+l +m++
  gi|1565548   580 KQKHDQFENN-IKVYPGLDTLFLFKLVSIIYPTSDFRHPIVTPCLVFMSQ 628  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                    L r++v   +dI++Glf ++++L++   SkR  P+V++ l + ++  + 
  gi|1565548   629 ILLRCKVKKKSDISKGLFVCTLILEYTVLSKRWSPAVINYLRGVIY-VSL 677  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqr..Lsl
                   pK   + + + P +F     +  +     ++l ++   + + p + + + 
  gi|1565548   678 PKPFSKVIKVIP-PFKSV--GDTSN---ILVLEENHKKSDIDPATvkMQI 721  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                    DLV   +  ++  + +++       +l+L+ e+   +  l A   If P
  gi|1565548   722 EDLVEVEMDDDYRLRTFVT-------ALNLLCEFEKHCSELDAAFSIFEP 764  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                   Il+L    s  + +p+k + ek +  +  +  l e   k   PLA  ++K
  gi|1565548   765 ILTLFECGSV-KRYPSK-VREKVKTLIDELKTLKE---KVLEPLAYDKKK 809  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   P+a+r+ eP+ E + D KR   +s     ke++e+ KL++klK+E K Ai
  gi|1565548   810 PKALRMYEPRIEVVHDGKRHKPMS-----KEKAEREKLLHKLKKETKSAI 854  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+R+D  F++ +++k++ a+d er  K+k i   +  q+ +l   
  gi|1565548   855 REIRRDNDFISKVKIKQQIASDAERKRKVKEIFGDAAMQQSEL    897  

gi|238845368|gb|EEQ35030.1|: domain 1 of 1, from 37 to 886: score 551.9, E = 7.3e-163
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                        e r     A + i+++fNPF++++  r++KF +        +g  
  gi|2388453    37    AAENRIKRNAALQAIREQFNPFEIRAPVRpsKFAVTTT--RPERGPA 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV R+ +ee+Rk+Tl +e++ +nK g+ +D+R+GE+++  +     E
  gi|2388453    82 HRPGVTRGLGEERRKQTLLKELQSRNKVGGLLDRRFGENDPSMT----PE 127  

                   eKMleRfsRErmSQlrLSKre.aynlnDGlEDveedGdrggsSv.....K
                       eR+ RE   Q r SK+e++ nl D  E    ++++g+s  + + +K
  gi|2388453   128 QRAAERYARES--QKR-SKKEgLFNLEDEDEGEMQLTHMGQSLFgvdagK 174  

                   DDl.DsleelgeeLsdddELadeaLDkdflalkrFeeeD.AeaeeeqrGA
                   DD++++l  l ee + +       + +    + +  +eD++e e++ r  
  gi|2388453   175 DDFnEELSGLEEESDSGTGKKRKRIVEEVDDMDGMADEDeDEEEQPER-- 222  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                   kKsK EVm+EiIaKSK yK Er+K Ke    l+  LD    d+      +
  gi|2388453   223 KKSKNEVMKEIIAKSKQYKYERQKSKEDDNELRAILDQGLPDVFAMMRGT 272  

                   kltsRKsGiKkprea......................kedtDaeYDlllk
                   k +       +p +a+++ +++++ ++++    ++++    D eYD  l+
  gi|2388453   273 KAA-------EPKPApgpapepphmnpdraallggkdRDEADREYDQRLR 315  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEe
                    M f+kR +Ps+RTKTeEE+  +Ea +L eLE+eRl+RM++ eE +d+E 
  gi|2388453   316 QMAFDKRSKPSERTKTEEEKIEEEAKRLQELENERLRRMRGEEE-SDEEQ 364  

                   EiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEd
                                + v+ +   +s  +D   fG  +          +e +
  gi|2388453   365 -----------ADGAVEEEFPDDSEPDDAKAFGLAQ----------AETS 393  

                   .....dEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAE.
                   ++  + Ed+d+ + d dD                 L d E   D L  E+
  gi|2388453   394 tglfgVEDEDDFIID-DD-----------------LVDTESAADVLLSEs 425  

                   .LEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKA
                   ++E +e eeDd  D  +  D E              l++  ++a      
  gi|2388453   426 dVESEE-EEDDADDTEFIGDLE--------------LPKDKPSAA----- 455  

                   NmKKsadTiP.ASLdrsipFtidcPktheelleLlkkldleDkplIVeRI
                        +dTi +A  d s++Ft++cP +h+ +l  l++ d e  p +V+RI
  gi|2388453   456 -----SDTISkAPNDPSLAFTYPCPESHDQFLKILEDVDIENTPVVVQRI 500  

                   ikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLe
                   + +hh  L+++N K kl+ Fs +L  h    +  l++Q    +  f  Le
  gi|2388453   501 RALHHASLHPDN-KAKLGEFSKILVDHT--AY--LANQSTQPP--FAVLE 543  

                   kLveaLielaqelPeklaislseellevikelaeeykknEhikyPSlkdL
                    L  + +++a+  Pe  a  +++ l+++          +  +  P  +dL
  gi|2388453   544 SLLRHVHSMAKTYPEEVATRFRSHLRDISDN------RP-LKLLP--GDL 584  

                   vfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvs
                   v++  v+ +F+TSD  H+VvTP++l m  +L + pv+Sl dIa G +++s
  gi|2388453   585 VLLTGVAMIFPTSDHFHAVVTPSILIMGRYLGQGPVNSLTDIAAGTYIAS 634  

                   iVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtF.erdRL
                   + L++q + kRy+Pe +++    L  llvp    +++  tP+ F+ r   
  gi|2388453   635 LCLQYQAYAKRYIPEFINFTLNSLS-LLVP----KEIKSTPGFFpVRSPE 679  

                   DslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlL
                    s  + L   + + v+   +  +    l D              l+ Sl 
  gi|2388453   680 SSIRLQLGNNASKDVQKFRFWDIFSPGLKD---------NDAESLKLSLI 720  

                   liKEvleLvEeiveiyy.klqAFiEIflPIlaLLsrys...lkeslpekR
                   +i   ++L+  +v+ +++kl+AF EIf P  a L+ + ++ +k s+p   
  gi|2388453   721 NI--LISLIDNAVGLWGtKLSAF-EIFEPTNAVLQHMAescSKGSIPTA- 766  

                   lkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDK
                   l+ +l   ++ +  l +  kk r PL l +H+P+aI +  PKFEE +   
  gi|2388453   767 LSGHLRQCLKTIKVLLATMKKSRRPLLLHNHRPLAIKSSIPKFEESF--- 813  

                   RsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEk
                    +Pd   yDpD+eR+el KLka +KrE+KGA+RElRKDa F+ar+ l Ek
  gi|2388453   814 -NPDRH-YDPDRERAELSKLKAEHKRERKGAMRELRKDANFIARESLREK 861  

                   aakdqerhEKmkkivnelqeqegAl<-*
                      d e+  K +++ +e+q +eg +   
  gi|2388453   862 KERDAEYEKKYRRLIAEIQGEEGRE    886  

gi|126332163|ref|XP_001373584.1|: domain 1 of 1, from 137 to 972: score 550.9, E = 1.5e-162
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++ +        ak     NPF+vk ++ KF ilGr   k ++++G 
  gi|1263321   137    GSQAGVQR----AKPPANSNPFEVKINRQKFHILGR---KTRHDVGL 176  

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+SRaka+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1263321   177 PGISRAKAIKKRTQTLLKEYKERDKSNVFTDKRFGEYNTKIS----PEEK 222  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  Er  Q+   K++ ynln     +ee+++ g+s    D++ +  
  gi|1263321   223 MMKRFALER--QRNNEKKSIYNLN----EDEELTHYGQS--LADIEKFND 264  

                   lgeeLsdddELadeaLDkdflalkrFeeeD........AeaeeeqrGAkK
                     ++ sd +E    +  + ++a+ +F++ ++  +++++  +eee +   K
  gi|1263321   265 IVDSDSDTEERGMLS--AELTAS-HFGGGGgllrkktsEPGEEEEK--PK 309  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   s kE +eE IaKSK  K Er+ ++e    l++kLD   k ++ ll+   +
  gi|1263321   310 SRKELIEELIAKSKQEKRERQTQRENALELTEKLDSDWKEIQFLLSHKTP 359  

                   tsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkE
                   +      Kk  e k+ +D  YD+ ++E+ fe  A+PsdR KTeEElA++E
  gi|1263321   360 K----SEKKDKEEKPKPDT-YDIMVRELGFEMKAQPSDRMKTEEELAKEE 404  

                   aekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfs
                    ++L +LE  Rl+RM + e   d+          kk+k++S+dDL D   
  gi|1263321   405 QARLKKLEADRLRRMLGKED--DEKS--------KKPKHISADDLND--- 441  

                   VEEDKPKfGfied.....lleREDNvdNeEddEdddeeaedsdDddsvnd
                           Gf +d+++++ll   D   N E d+   e+ + ++D +++ d
  gi|1263321   442 --------GFVLDkddrrLLSYKDGKINQEIDDPNEEGKAQEEDSEGEED 483  

                   GtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvl
                               +d E++DD       D     +  e + EE D E ++ 
  gi|1263321   484 -------QQPDTEDSEESDDP------DNHSDLESNEASEEE-DIETENQ 519  

                   kdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkt
                   k+         +++++++    KA m   a          +p+t+  P +
  gi|1263321   520 KK----KHIHAPEKNPSGG-NQKA-MIEAARS-------ELPYTFAAPDS 556  

                   heelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqh
                   +eel  Ll++ ++e+   ++eRI k++hp L+ +N K kl K+  +LL +
  gi|1263321   557 YEELKSLLSGKSTEQQLVVIERIQKCNHPSLAVGN-KAKLQKLFGFLLEY 605  

                   IKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseelle
                   I     Dl+         +    kL   L+ l q +Pe++  s   +l++
  gi|1263321   606 I----GDLATMTPPD---LKTIDKLIVQLYNLCQMFPEFASSSVKFVLRD 648  

                   vikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllm
                   v  e+ e +       +P l+ L+++k++g+lF+TSDf H+VvTPal  m
  gi|1263321   649 VVHEMEEMIEIKGRAAFPGLDVLIYLKIIGILFPTSDFWHPVVTPALVCM 698  

                   aevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftl
                   ++ L ++pv Sl+d+ +Glf + ++L+++s S R+vPe+++ l + L+ +
  gi|1263321   699 SQILTKCPVMSLQDVIKGLFVCCLFLEYVSLSQRFVPELINVLAGVLH-M 747  

                   lvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                     p +      ++  +F     +  ++   l+ + ++ ++       L+l
  gi|1263321   748 ATPNKATRGYTLVH-PFKPL--GKNSE---LLLVSEKEDMDTWSKKGLPL 791  

                   aDLVtqtiteefpvd..alrsSlLliKEvleLvEeiveiyyklqAFiEIf
                          + e  ++ ++  r S   +   l+L+      y  l++ +EI+
  gi|1263321   792 SK--VNGLKEGSKSEtnHIRLSCICV--CLNLIKRCLAMYNTLPSLPEIM 837  

                   lPIlaLL.sryslkeslpekRlkeklldavelveKltedakkerKPLAlq
                    PI  LL+  ++    +p   l+e   + ++      e       PL   
  gi|1263321   838 EPIRVLLtDHIPE-CGYPRE-LQELSQSILQEMGNREE----TYQPLVCE 881  

                   eHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkK
                   + KPv + +  PK   + +  R  + s     ke  e++ L +k+KrE K
  gi|1263321   882 KSKPVPLKMFTPKLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFK 926  

                   GAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   GA+RE+RKD +F ar  l E    d+er  K+k +   l +qeg+    
  gi|1263321   927 GAVREIRKDNQFLARMQLSEIMERDSERKRKVKQLFGSLATQEGEW    972  

gi|212541386|ref|XP_002150848.1|: domain 1 of 1, from 36 to 902: score 548.2, E = 1e-161
                   *->keedreeKKK...AvakiqkefNPFdvkv.akr.KFdilGrsKtkvK
                      +  +r++  +++ A aki+++fNPF++k+++++ KFd+  r      
  gi|2125413    36    GAKARQSRIQrnaALAKIREQFNPFEIKApSRNaKFDVTTRDGSSKA 82   

                   geeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                   g    PGV +  +ee+R+ Tl +e+  +nK+g++ D+R+GE+++  +   
  gi|2125413    83 GNYSRPGVTKSLGEERRRETLLKELHSRNKTGGIMDRRFGENDPTMT--- 129  

                   LeEeKMleRfsRErmSQlrLSKreaynlnDGlEDvee....dGdrggs..
                     Ee   eRf RE   Q+++ K ++ nl   ++D+ee + ++G r +s +
  gi|2125413   130 -PEERAAERFARES--QRKMRKENLFNLE--EDDDEEleltHGGRSLSfg 174  

                   .SvK...DDlDsleelgeeLsdddE..........LadeaLDkdflalkr
                   +++  ++DD+ +    g e sdd+E+++++++     de+   d   ++ 
  gi|2125413   175 dAINlngDDFAENDINGGESSDDEEssrkrkraaaVEDEV--DDMDGMAS 222  

                   FeeeDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidk
                     ++ A   e+ r  kK+K+EVm+E+IaKSKlyK Er+K+Ke   Dl+ +
  gi|2125413   223 EDDDEADETEPLR--KKTKAEVMKEVIAKSKLYKYERQKAKEDDDDLRAE 270  

                   LDeNfkdLlsllamekltsRKsGiKkpreaked.................
                   LD+    +  l    k+       K+p ++ ed    ++++    +++++
  gi|2125413   271 LDKGLPEIFELMRGVKPP-----PKTPEPPREDaaimnpdraallngkdr 315  

                   ..tDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkR
                    + D eYD+ lk M f+kR +P+dRTKTeEE+Aq+Eae+L  LE eRl+R
  gi|2125413   316 aeADVEYDKRLKQMAFDKRSAPTDRTKTEEEKAQEEAERLKRLELERLRR 365  

                   MeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedl
                   M+++e  +++E+  GG +         v+D+++ + + +D   fG    +
  gi|2125413   366 MRGDED-SESEA--GGADD------ELVEDEGA-DFIPDDAKAFGLTSAV 405  

                   le...REDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddE
                   + + +RE  v+  Edd  +d+   d d d+  +                 
  gi|2125413   406 ETearRELDVE-DEDDFIIDDDLVDMDSDENLSF---------------- 438  

                   neDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeai
                    e D+   E+ED e e +dE + d E        k LK+       +++ 
  gi|2125413   439 IESDE---EMEDSEMESEDEGLMDDE------FSKSLKN---LVGTESGS 476  

                   kasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDk
                   k+    K+             d  +++t++cP +h+e+l+ lk+   +D 
  gi|2125413   477 KNVPTGKT-------------DDGLAYTYPCPQSHDEFLAILKDVTAKDI 513  

                   plIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQd.ikk
                   p IV+RI+ ++hp L+ +N K+kl+ Fs v   h+   +  +++Q ++++
  gi|2125413   514 PVIVQRIRALYHPRLHSDN-KSKLGVFSKVIVDHV--VY--MANQTgSIS 558  

                   nLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhi
                      f   e L  + +++a+ ++e  a  +++ l+e+  e       +   
  gi|2125413   559 ---FNIIENLLRHIHSMAKTNSEPVAHAFRNHLREMAVE------RP--- 596  

                   kyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdI
                     +  +dLv++  v  +F+TSD  H+VvTPa l +a +L +s v+  +d 
  gi|2125413   597 LNLLPGDLVLLTGVMTIFPTSDHFHPVVTPANLCIARYLGQSAVNNTSDL 646  

                   aiGlfLvsiVLkfqsiSkRyvPeVv.yalqqiLftllvpKRDVellsitP
                   a G++L+ + L++q   kRy Pe ++y l+ i + l+         + + 
  gi|2125413   647 ATGAYLAALSLEYQTLAKRYMPEFMnYCLSAICL-LSPT----PATQQVG 691  

                   LtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp.
                       rd     +k    + l     st  e+ + s  D     + e+ + 
  gi|2125413   692 FVLLRD-----SK----ESLRLESSSTSSEIRKISFWD----VVAEDAKa 728  

                   .vdalrsSlLliKEvleLvEeiveiyyklqAFiEIfl...PIlaLLsrys
                   ++ +l+ Sl +    ++L+  + + +   +A+iEIf + +PIl+ L +  
  gi|2125413   729 sSEDLKISLIST--FVSLLDAAADLWADKSAYIEIFTsakPILQHLKKSF 776  

                   lkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrlleP
                    k s p   l+  +  ++ ++  +    +  r PL l +H+P+aI    P
  gi|2125413   777 TKSSSP---LSTQITTTLHKLKTSSTQSQHTRRPLLLHNHRPLAIKQSIP 823  

                   KFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakF
                   KFEE +    +Pdk  yDp +eR+el+KLka +KrE+KGA+RElRKDa F
  gi|2125413   824 KFEEDF----NPDKH-YDPNRERAELAKLKAEHKRERKGAMRELRKDANF 868  

                   varlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   var+ lkEk  kd ++  K +++ +e+q +eg +   
  gi|2125413   869 VAREQLKEKKEKDAAYEKKYRRLIAEIQGEEGRE    902  

gi|119484134|ref|XP_001261970.1|: domain 1 of 1, from 37 to 899: score 548.0, E = 1.1e-161
                   *->keedreeKKKAvakiqkefNPFdvkva.krKFdilGrsKtkvKgeeG
                      +         A + i+ +fNPF++kv++++KFd+  r     K + G
  gi|1194841    37    SAQNLVQRNAALQAIRDRFNPFEIKVTsRNKFDVTTR-DGGPKPAAG 82   

                   k..PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                    ++PGV +  +eekR++Tl  e + knK g+++D+R+GE ++  +     
  gi|1194841    83 LsrPGVTKSLGEEKRRQTLLREMERKNKIGGIVDRRFGEDDPTMT----P 128  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv......
                   Ee   +Rf RE   Q +L K ++ nl D  ED+  +++ g++   +++ +
  gi|1194841   129 EERAAARFARES--QKKLRKESMFNLEDDDEDDFQLTHKGQTLTlgddvp 176  

                   KDDlDs...leelgee...........LsdddELadeaLDkdflalkrFe
                   +DD++++ +++e ++++++ ++++++ L+dd+EL d +          F 
  gi|1194841   177 QDDFEEdlrGLEEDQSdsemprkrkriLDDDEELEDFV----------FD 216  

                   eeDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLD
                   +eD e + e++   KsK EVm+E+IaKSK+yK Er+K+Kee  Dl+++LD
  gi|1194841   217 DEDGEDQPERK---KSKHEVMKEVIAKSKFYKLERQKAKEEDDDLREELD 263  

                   eNfkdLlsllamekltsRKsGiKkpre.............akedtDaeYD
                   +   dL   l   k+  +    K+  e+ ++++    +++a  d+ +eYD
  gi|1194841   264 KGLPDLFDMLRGVKPPPKPEPAKDDLEsmnpdraallkgtADDDPNKEYD 313  

                   lllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEle
                     lk + f+kR +P+dRTKT  E+A +Ea +L +LEeeRl+RM++ +E +
  gi|1194841   314 QRLKQLTFDKRSQPTDRTKTAVEKAEEEAQRLKALEEERLRRMRGEQE-S 362  

                   dgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvd
                   d+Ee+    ES       +++D dD  s+ +D   fG  +          
  gi|1194841   363 DEEEDDEEGESE-----TGGEDSDD-ESIPDDAEAFGLKQ---------P 397  

                   NeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELE
                        E+   + ed+dD     d  dl   +  v     ++D +     E
  gi|1194841   398 SPQTNEGPEMGVEDEDD-FIIDD--DLVETRSNVSLSFDESDGE-----E 439  

                   DkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmK
                     + ee+ Ee + EE         +L +    p  +++ +      A   
  gi|1194841   440 GSS-EEESEEEDEEE--------DELINGLTLPTSKSGDSTAAADGA--Q 478  

                   KsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikah
                   K ++         +++t++cP  he +le +k+    D p++++RI+ +h
  gi|1194841   479 KTSEG--------LAYTYPCPEDHESFLEVIKDVPMNDLPTVIQRIRALH 520  

                   hpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLve
                   hp L+++N K kl+ F +vL +h+   +  ++eQ+   +  f  Le    
  gi|1194841   521 HPRLHADN-KTKLGRFAAVLVRHV--AY--MAEQPEHPP--FNVLEAILR 563  

                   aLielaqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFk
                   + ++la++ Pe        ++  ++ +   e+        +  +dLv + 
  gi|1194841   564 HIHSLAKSHPES-------VCMAYR-RYLREIATD-RPLSLRAGDLVILT 604  

                   LvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLk
                    ++  F+TSD  H++ TPa l +a +L +  ++Sl d   G++ +s+ L+
  gi|1194841   605 GIATTFPTSDHFHAIATPAHLCLARYLGQGAIDSLGDYTTGAYAASLCLQ 654  

                   fqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslek
                   +q iSkRy Pe ++ +  +L   l p      l   P   +r   +s  +
  gi|1194841   655 YQTISKRYMPEFINYVLNALC-NLCPTEPTSSLGFFP---ARGSHGSMRL 700  

                   GLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEv
                              +s  l p +L   D +    +     d l+ Sl      
  gi|1194841   701 ----------IPSKQLNPRKLRFWD-IATAQSDQRAQDELKLSLIHT--F 737  

                   leLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekRlkeklld
                   + L+  +++ + + +AF EIf  ++  L   ++s k +l +  ++ +l +
  gi|1194841   738 VTLLNSASDLWAGKSAFFEIFEQVQRVLRHVskSAKGKLSSV-VQDNLQS 786  

                   avelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksS
                   ++ ++      a++ r PL l +H+P+aI +  PKFEE +    +Pdk  
  gi|1194841   787 TLDKLDTHLSRARATRRPLLLHNHRPLAIKTAIPKFEETF----NPDKH- 831  

                   yDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqer
                   yDp +eR+eln Lka  KrE+KGA+RElRKDa F+ar++l Ek   d e+
  gi|1194841   832 YDPNRERAELNRLKAEFKRERKGAMRELRKDANFIAREKLREKKERDAEY 881  

                   hEKmkkivnelqeqegAl<-*
                     K k++v+e+q +eg +   
  gi|1194841   882 EKKYKRLVAEIQNEEGRE    899  

gi|169861869|ref|XP_001837568.1|: domain 1 of 1, from 39 to 892: score 545.7, E = 5.3e-161
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                           ++K     +i  + NPFd kv++ K d++Gr   + Kg  Gk
  gi|1698618    39    EKLKTAAK---LEEIHRRLNPFDEKVTRLKHDVGGR---RLKGVTGK 79   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P   ++ ++e+Rk+ l +e + k + g+++D+R+GE+++  s     Ee 
  gi|1698618    80 PAKAKQAGLEQRKKSLLKEWEEKGRAGGIVDRRFGENDPTMS----LEER 125  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvK.DDlDsle
                   MleRf+REr  Q+  S   a  +n  lED  e+++ g+s  K DD+D + 
  gi|1698618   126 MLERFTRER--QRA-STSAA--FN--LEDEDELTHYGQSLSKlDDFDDVG 168  

                   elgeeLsddd...ELadeaLDkdflalkrFeeeDAea.eeeqrGAkKsKk
                   +  ++  + + ++  + e+  +  +++++F ee+ e++ +e+   kKsK+
  gi|1698618   169 LRSDSDEENEvtgQIDREV--VSKTHFGGFDEEGEEGsDDEGPARKKSKA 216  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt..
                   EVm E+ aKSK  K  r+ eKee e  + +LD +f dL  ll   k+t+ 
  gi|1698618   217 EVMAEVMAKSKEHKLRRQMEKEEEENIRFELDNQFSDLRELLFAAKPTpa 266  

                   ......sRKsGiKkpreak.....edtDaeYDlllkEMvfekRAsPsdRT
                   ++++++      K+p  a+    +e  D  YD  ++E+ f+kRA+P dRT
  gi|1698618   267 ppttseNAEEPPKDPDAAIlalapETQDHAYDQRVRELAFDKRAKPKDRT 316  

                   KTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvr
                   KTeEElA +++e L++ E  R +RM++  E +d+E     E   k  + r
  gi|1698618   317 KTEEELALEAKEALEKAERRRQRRMQGLPE-SDSED----EGKGKGKRKR 361  

                   SvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddE........ddde
                   ++dDLdD + + ED    G + +l e       eE++E ++++++++dd+
  gi|1698618   362 GGDDLDD-DFI-EDDEWEGLGSGLKE-AAAASDEESFEfgsgseedGDDD 408  

                   eaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEe
                   ea  +++    +                E+eD d     ED eGeeD +e
  gi|1698618   409 EADGEEG----SG---------------EEEDED-----EDSEGEEDAGE 434  

                   DedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASL
                    e+E                 + l+ +  k  +k KA   Ks        
  gi|1698618   435 -EGEH----------------EELVTSVKKSKGKGKA---KSTGD----- 459  

                   drsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRK
                      ip+t++cP  h+e+le  +  d +   ++V+RI+ ++h  L ++N K
  gi|1698618   460 --EIPYTFPCPEHHDEFLEIMETIDDKHISTVVQRIRALYHTSLSPDN-K 506  

                   eklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelP
                   +kl  F  vL  hI  L+      +++++  +   +   ++L  +++  P
  gi|1698618   507 SKLQTFGCVLIDHI--LY-----SASISPPRLGVISAIYPHLTAITKAYP 549  

                   eklaislseellevike....laeeykknEhikyPSlkdLvfFkLvgllF
                      a+ + e+l  + k  +++la    ++E   +P l+ L  ++ +g l+
  gi|1698618   550 IPIARYFNEKLALMHKNlkrgLAQGAHNPESRTWPGLGELAILRVIGQLW 599  

                   sTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSk
                   +TSD  H+Vv+P   lm  +L  ++v++l+dIa GlfL+++ L++   Sk
  gi|1698618   600 PTSDLHHAVVSPTRVLMGAYLGLCRVRTLSDIASGLFLCTLWLQYEALSK 649  

                   RyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldn
                   R+vPe v++l  +L+  l p    e +   P+tF  +  D l +      
  gi|1698618   650 RLVPEAVTFLVNALL-HLAP-HRFESIAALPGTFPSP--DFLTR---TTS 692  

                   lfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEe
                     + k s   +  +L+      qt++    + + ++ + li  +l L+  
  gi|1698618   693 GLTLKKSKNPPTPQLP--N--LQTLLSTKDSSDEQAKIDLISMALDLLTR 738  

                   iveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKl
                       y++l AFiE f P+++ L  +        kRl+e +   + ++++ 
  gi|1698618   739 YANMYKSLEAFIELFEPVQTVLEGLER------KRLHEAHRTQLAKLTDM 782  

                   ted....akkerKPLAlqeHKPvaIrllePKFE...EnyDDKRsPdksSy
                        + a+  r PL lq HKP+ I + +PKF +++ ny     +     
  gi|1698618   783 MTRllkfAHEGRQPLRLQAHKPIPIATYVPKFDsttSNY-----LRQR-- 825  

                   DpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerh
                   DpD e+ e +KL+ + K E+KGAiRElRKDa+F a +  + +  kd +++
  gi|1698618   826 DPDHEKNEAAKLRNQYKQERKGAIRELRKDARFLAGVEQQKQIEKDRAYN 875  

                   EKmkkivnelqeqegAl<-*
                   E mk++   +  +  +    
  gi|1698618   876 ERMKRVFSSIEPERAEQ    892  

gi|149756960|ref|XP_001489859.1|: domain 1 of 1, from 22 to 843: score 543.9, E = 1.9e-160
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +  +r              NPF+vk ++ KF +lGr   k ++++G 
  gi|1497569    22    GGRARPNP-----------NPFEVKINRQKFQVLGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a++kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1497569    55 PGVSRARAIQKRTQTLLKEYKERDKSNVFTDKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q++  K++ ynln     +ee+++ g+s    D++    
  gi|1497569   101 MMKRFALEQ--QRQHEKKSIYNLN----EDEELTHYGQS--LADIEKHND 142  

                   lgeeLsdddELadeaLDkdflalkrFeeeD......AeaeeeqrGAk.Ks
                     ++ sd dE    +  + ++a+ +F++ ++  +++ + +e  +G k+Ks
  gi|1497569   143 IVDSDSDADEPGTLS--AELTAA-HFGGGGgllhkkTSQQEGEEGEKpKS 189  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                    k  +eE IaKSK  K Er++++e    l++kLD   k ++ lla   +t
  gi|1497569   190 RKALIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLA--HKT 237  

                   sRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEa
                     Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTeEElA++E 
  gi|1497569   238 -PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQ 284  

                   ekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV
                   e+Lr LE eRl+RM +       E         +++ + S+dDL D    
  gi|1497569   285 ERLRSLEAERLRRMLGKDD----EN-------SRRPSHMSADDLSD---- 319  

                   EEDKPKfGfied.....lleRED...NvdNeEddEdddeeaedsdDddsv
                          Gfi+++++++ll   D++ Nv+ e + E  d e+e+++++ds 
  gi|1497569   320 -------GFILGeddrrLLSYKDgkmNVEEEQSREASDGESEEEEGEDSG 362  

                   ndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEld
                                  d E++DD       D          +d ESD E +
  gi|1497569   363 EE-------------DPEESDDP------DGH--------SDLESDGESE 385  

                   vlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcP
                     +   e e    +g+ +      KA  +  a T        +p+t+  P
  gi|1497569   386 EGSGTPEKERRHAPGKRLTSD-GQKA--REAART-------ELPYTFVAP 425  

                   ktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLL
                    ++eel  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LL
  gi|1497569   426 ESFEELKSLLSGKSIEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLL 474  

                   qhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseel
                    ++     Dl+  d      +    kLv  L+ l q +Pe +  s   +l
  gi|1497569   475 EYV----GDLATNDPPD---LRVIDKLVVQLYNLCQMFPESASDSIKFVL 517  

                   levikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPall
                   ++   e+   +       +P l+ L+++k+ g lF+TSDf H+VvTPal 
  gi|1497569   518 RDAMHEMEGMIETKGRAAFPGLDVLIYLKIAGMLFPTSDFWHPVVTPALV 567  

                   lmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLf
                    m++ L ++pv+ l+d+ +Glf + ++L ++s S R++Pe++++l +iL+
  gi|1497569   568 CMSQLLTKCPVRCLQDVVKGLFVCCVFLDYVSLSQRFIPELINFLLGILY 617  

                   tllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrL
                       p +      ++  +F     +  ++   l+ +    ++       L
  gi|1497569   618 -IATPNKQNQGYTLVH-PFRAF--GKNSE---LLLVSDEEDMATWQRKSL 660  

                   sla...DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFi
                   sl   + L  qt te+  +++   S L +   l Lv   v  y+ l++F 
  gi|1497569   661 SLHwasGLKAQTKTEANHTRL---SCLAV--CLALVKRCVLMYGVLPSFH 705  

                   EIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLA
                    I  P  aLL        + ++  ++ l    + +    e  k    PL 
  gi|1497569   706 DITRPLRALLTEHLA---DCSH--PRELQELCQSILTEMENQKHHCQPLI 750  

                   lqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrE
                     + KPv + l  P+   + +  R  + s     ke  e++ L +k+KrE
  gi|1497569   751 CEKSKPVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKRE 795  

                   kKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-
                    KGA+RE+RKD +F ar  l E    d er  K+k + n l +qeg+   
  gi|1497569   796 FKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW   843  

                   *
                    
  gi|1497569     -   -    

gi|154301059|ref|XP_001550943.1|: domain 1 of 1, from 34 to 899: score 541.7, E = 8.8e-160
                   *->keedreeKKK...AvakiqkefNPFdvkvakr.KFdi......lGrs
                      +   +e K K++ A   i+ +fNPF++k ak +KF ++++++ +Gr 
  gi|1543010    34    NGANKEKKIKrsvALNGIRDQFNPFEIKQAKApKFEVtsnktlGGR- 79   

                   KtkvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkh
                     + Kg + kPGV R+ aee R++Tl  e + +n+ g++iDkR+GE+++ 
  gi|1543010    80 --ISKGIK-KPGVARGLAEENRRKTLLVEMQSRNRVGGIIDKRFGENDPS 126  

                   LsGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDve...edGdrg
                          E+KMleRf+ E+  Q+    ++   ++  lED e ++e++++g
  gi|1543010   127 MA----PEDKMLERFTQEK--QRG--HKNSSAFD--LEDEEfsgELTHMG 166  

                   gs......SvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDA
                   +s + ++++++DD+D+     e+L + d  + e+ D+ + alkr +++  
  gi|1543010   167 QSlsldgpAIRDDFDE-----EGLELSDADDHES-DEERQALKRRRGSNS 210  

                   eaeeeqrGA......kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidk
                   e+ +e +  +  +++kKsK+EVm+E IaKSK  K Er+++K+  eDl+++
  gi|1543010   211 EGSDEDEEGtalperKKSKQEVMKELIAKSKMHKYERQAAKDDDEDLREE 260  

                   LDeNfkdLlsll..amekltsRKsGiKkpreaked...............
                   LD+ + ++  ll+++  k+         p  a ed ++ ++++    +++
  gi|1543010   261 LDKDMSSIHELLrgMAHKPP------PAPAAAPEDipgmnperialmngg 304  

                   ....tDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRl
                   ++ ++ +eYD+  + M  +kR +P++R KTe+E+  kE  +LreLEe Rl
  gi|1543010   305 drakLEKEYDIRMRQMAQDKRSQPTERSKTEDEKMEKESRRLRELEEKRL 354  

                   kRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfie
                   +RMe+  E++d Ee           + r +dD+      EE+   +G ++
  gi|1543010   355 RRMEGVAEDSDDEE---------ENRTRRADDEEE--EEEEEEEDYGLGD 393  

                   dlleREDNvdNeEddEd....ddeeae..........dsdDddsvndGtd
                   ++  R    + + ddEd+   dd++ +++++ ++++++sd++d+++d   
  gi|1543010   394 GIKTRPSAAELGADDEDdfviDDDLVAsgsdidesegESDGEDGESD--- 440  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                                neDD+        eG   +Ee +  E           
  gi|1543010   441 -------------NEDDE------FLEGLLTEEEAKRPE----------F 461  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                        +pl++  + a                  ++ ++++t++cP +hee
  gi|1543010   462 LTGANAPLPEVELPAK---------------NGVNGDLAYTFPCPQSHEE 496  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   lle  k+ +l D p++V+RI+ ++hpKL  eN K kl+ Fsv L  hI  
  gi|1543010   497 LLEITKGIALLDLPTVVQRIRALYHPKLNSEN-KVKLGSFSVSLVSHI-- 543  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                    +  l++Q+ + +  f  Le    + ++l++ +P   a s++  l e+  
  gi|1543010   544 SY--LANQAQRPP--FSVLENIIRHIHSLSKTFPLEIANSFRRHLDEINQ 589  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                     a + k           dLv +  +g +F+TSD  H VvTPa+l+m  +
  gi|1543010   590 SRALALKAG---------DLVVLTAIGTIFPTSDHFHQVVTPAILTMGRY 630  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L +   + l+  a G++L+++ L++q+ SkRyvPeV  +++  L   l p
  gi|1543010   631 LGQKIPQDLSNYATGAYLCTLCLQYQRLSKRYVPEVAGFIENTLC-ALAP 679  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDL
                         l   P+ F         +  P+  +   k s  +   +   +D 
  gi|1543010   680 ----TKLAKIPGSFPYH------E--PKSSVRIEKASASD--RQIEFYD- 714  

                   Vtqtiteefpvda...lrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                       i  e++ d++++l+  lL     +  +    + +   +AF E+f P
  gi|1543010   715 ---CIPQELSADDeesLKVALLEA--NIKILNSSADLWSEKSAFTEVFEP 759  

                   IlaLLsryslkeslpekRlkeklldavel.veKl...tedakkerKPLAl
                    l+ L  +++ +s  +k l+e     + ++++K+++    a+  r PL l
  gi|1543010   760 ALTILKHLGS-KSCRSK-LPESSQTLIRKsISKFqtmLQLAHLARRPLEL 807  

                   qeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEk
                     HKP+aI +  PKFE  y    +Pdk  yDpD+eR+e +KLka +K+E+
  gi|1543010   808 HHHKPLAIKTSIPKFEDSY----NPDKH-YDPDRERAETAKLKAEHKKER 852  

                   KGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   KGA+RElRKD+ F+ar+ l +k  kd +   Kmk++ +e+q +eg +   
  gi|1543010   853 KGAMRELRKDSNFIARESLRQKKEKDAAHEKKMKRLIAEIQGEEGKE    899  

gi|58262956|ref|XP_568888.1|: domain 1 of 1, from 37 to 916: score 541.0, E = 1.5e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       e+dr+ K     +i+k  N Fd + ++ K d++Gr     Kg +G 
  gi|5826295    37    RETDRAKKVEKLEEIRKNLNKFDERETRVKHDVGGR---NLKGVVGR 80   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P+ S++ ++e+Rk+Tl  e + +  +g f D+R+GE+++  s     E+ 
  gi|5826295    81 PSASKQAGLEQRKKTLLPEHQLRDHRGTFRDRRFGENDPSMS----IEDR 126  

                   MleRfsRErmSQlrLSKreaynlnDGlEDv.............eedGdrg
                   MleR++REr  Q+   K+ + nl D  ED + ++ +++   +++++G r 
  gi|5826295   127 MLERYTRER--QRGQGKKGMFNLEDEDEDEpfgelddgfalggLTHGGRS 174  

                   gsSvKDDlDsleelgeeLsdddELadea....LDkdf...lalkrFeeeD
                         Dl +     ++L d+dE   e + +++Dk+  ++ ++++Fee  
  gi|5826295   175 VM----DLPGDDFVAQGLADEDEDEEENragrIDKRVvskVHFGGFEEAM 220  

                   AeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNf
                   +e   e++   KsK+EVm EiIaKSK  K Er+ ++e    l+++LD   
  gi|5826295   221 DEDLPEKK---KSKQEVMAEIIAKSKEHKYERQQQREMDAELREELDGDI 267  

                   kdLlsllamekltsRKsGi.....K...kprea...kedtDaeYDlllkE
                    dL+ lla   +t   + + ++++K +++p++ ++++  +D eYD  ++ 
  gi|5826295   268 ADLQMLLAENAPTTPAATLfpttsKlhpDPMPVpggEVIGDGEYDQIVRS 317  

                   MvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeE
                   + f+ RA+P  RTKTeEE+A +E+e L++ E  Rl+RM++    +dgEe 
  gi|5826295   318 LAFDARAKPKNRTKTEEEIALEEKENLEKAEAKRLRRMRGENV-SDGEE- 365  

                   iGGEESvkklkv....rSvdDLdDsfsVEEDKPKfGfiedlleREDNv..
                      E S kk k ++++  +dDL D + V ED    G ++  +e E  v +
  gi|5826295   366 --EEGSRKKRKAddkkPDADDLED-DYV-EDEALLGPGLTREEIETMVls 411  

                   ..dNeEddEdddeeaedsd...DddsvndGtdlkqkKeavLkddEneDDd
                   +++++ ddE dde   +++++ D+d +                  ++D +
  gi|5826295   412 gsEAGSDDEQDDEDGREEEesfDEDAEEE---------------NESDAE 446  

                   LGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvk
                       +ED     + Ee+++ E                  +++  +k +  
  gi|5826295   447 --SAMEDLT---ENEELSVSE----------------SEEVEPVVKRT-- 473  

                   eKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVe
                    K   KK a T      + ip+t++cP + ee+ e +  l     p++V+
  gi|5826295   474 -KG--KKTART---EKVKEIPYTFPCPANIEEFEEIVDPLEDSALPTVVQ 517  

                   RIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqL
                   RI+ +hhp L+ +N Kekl  F  vL  ++  L   ls  ++     f L
  gi|5826295   518 RIRALHHPSLAQGN-KEKLQEFLGVLIDYV--LI--LSSRPSPP---FSL 559  

                   LekLveaLielaqelPeklaislseellevike....laeeykknEhiky
                    + Lv++L  l +++P  +a  + e+++ + k  +++la     ++ + +
  gi|5826295   560 IQTLVPHLTALVKLNPITAAAHFVEKIKLMQKNlsrgLARGAARPDSKTF 609  

                   PSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIai
                   P    L +++Lvgl +sTSD  H+Vv Pa llm ++Ls+s+v+Sl+d a 
  gi|5826295   610 PGAPELALLRLVGLFWSTSDYSHPVVVPAVLLMGQYLSQSRVRSLRDLAS 659  

                   GlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRD.VellsitPLt
                   GlfL+s+  ++ s SkR +Pe v+++   ++  l p+R + e +   P  
  gi|5826295   660 GLFLCSLLAQYESLSKRILPEAVNFVASSIL-ILLPRRKgAEVNRTYP-- 706  

                   FerdRLDslekGLPldnlfavkestllepqrLslaDLVtqti.teefpvd
                      d    l+   P   l  + +s+ ++ q L l   +t   +  e    
  gi|5826295   707 ---D----LKA--PSTSLYLNLPSSVVPSQPLDLGSAITAVGdQDEEEAE 747  

                   alrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslp
                   +l+  lL +  +  Lv  + + y    AF E + P+ + L +    ++l 
  gi|5826295   748 QLKGGLLVV--ACKLVDKFAGLYLDSEAFVELMSPVKQVLEQSRA-KKLS 794  

                   ekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEny
                   +  l   l +++ +++K        r PL lq+HKP+ I + +P+FEEn+
  gi|5826295   795 SE-LNMVLTSTLTALSKRLSNTLSTRRPLTLQSHKPIPIASYAPRFEENF 843  

                   DDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRl
                        P+k  yDpD eR   +KLka  K+E+KGA+RElRKD +F a +++
  gi|5826295   844 ----APGKH-YDPDTERNASAKLKALYKKERKGAMRELRKDNRFLAGEKA 888  

                   kEkaakdqerhEKmkkivnelqeqegAl<-*
                    E+  kd+e+++ m+k++  + ++  ++   
  gi|5826295   889 REQGEKDKEYNARMRKAEGSITVERAEE    916  

gi|119602895|gb|EAW82489.1|: domain 1 of 1, from 19 to 847: score 540.2, E = 2.5e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1196028    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1196028    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1196028   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1196028   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1196028   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1196028   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1196028   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1196028   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1196028   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1196028   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1196028   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1196028   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1196028   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1196028   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1196028   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|1196028   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1196028   715 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   + +  R  + s     ke  e++ L +k+KrE KGA+
  gi|1196028   760 PVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAV 804  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+RKD +F ar  l E    d er  K+k + n l +qeg+    
  gi|1196028   805 REIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    847  

gi|55769587|ref|NP_003694.1|: domain 1 of 1, from 19 to 847: score 540.1, E = 2.6e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|5576958    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|5576958    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|5576958   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|5576958   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|5576958   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|5576958   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|5576958   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|5576958   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D    + +   e EE     ++ k  
  gi|5576958   368 ---------EDTEESDSP------DSH-LDLESNVESEE-----ENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|5576958   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|5576958   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|5576958   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|5576958   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|5576958   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|5576958   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|5576958   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|5576958   715 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   + +  R  + s     ke  e++ L +k+KrE KGA+
  gi|5576958   760 PVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAV 804  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+RKD +F ar  l E    d er  K+k + n l +qeg+    
  gi|5576958   805 REIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    847  

gi|2792366|gb|AAB97011.1|: domain 1 of 1, from 35 to 863: score 540.1, E = 2.6e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|2792366    35    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 70   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|2792366    71 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 116  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|2792366   117 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 155  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|2792366   156 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 202  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|2792366   203 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 250  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|2792366   251 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 297  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|2792366   298 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 337  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|2792366   338 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 383  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D    + +   e EE     ++ k  
  gi|2792366   384 ---------EDTEESDSP------DSH-LDLESNVESEE-----ENEKPA 412  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|2792366   413 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 450  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|2792366   451 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 497  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|2792366   498 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 542  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|2792366   543 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 592  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|2792366   593 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 641  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|2792366   642 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 685  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|2792366   686 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 730  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|2792366   731 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 775  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   + +  R  + s     ke  e++ L +k+KrE KGA+
  gi|2792366   776 PVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAV 820  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+RKD +F ar  l E    d er  K+k + n l +qeg+    
  gi|2792366   821 REIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    863  

gi|224050190|ref|XP_002195362.1|: domain 1 of 1, from 14 to 855: score 539.6, E = 3.8e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       ++++   K A a +++  NPF+vkv++ KFdilGr   k K ++G 
  gi|2240501    14    PSTAKGPVKSAMAVVKS--NPFEVKVNRQKFDILGR---KTKNDVGL 55   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka+ kR +Tl +e+k + K+++f+DkR+GE     s     EeK
  gi|2240501    56 PGVSRSKAIKKRNQTLLKEYKEREKTNVFKDKRFGEYSTKIS----PEEK 101  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf+ Er  Q    K++ ynln     +ee+++ g+s     l ++e+
  gi|2240501   102 MIRRFTLER--QQNYGKKNIYNLN----EDEELTHYGQS-----LAEIEK 140  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                   l +  + d+d +    L + ++a+ +F++ ++  +++ + e ++e +   
  gi|2240501   141 LNDIVDSDsDTEERGTLSAELTAA-HFGGGGgllrkkvsSEQQDEEEEKP 189  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE+IaKSK  K+Er+  +e    l++kLD+  k ++ l+a  +
  gi|2240501   190 KSRKELIEEMIAKSKQEKQERQTRRESALELTEKLDKDWKEIQTLIA--R 237  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks  K+  + k+ +D  YD  ++E+ fe  A+Ps+R+KTeEElA++
  gi|2240501   238 KT-PKSERKDKEVEKPKPDE-YDMIVRELGFEMKAKPSERLKTEEELAKE 285  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E ++L +LE  Rl+RM++  E    E+        k++ + S+dDL D  
  gi|2240501   286 EQARLQKLEADRLRRMRGIDE----EA------NKKRPSHTSADDLAD-- 323  

                   sVEEDKPKfGfied.....lleRED...NvdNeEddEdddeeaedsdDdd
                            Gfi+d+++++ll   D++ N++NeE+ E + e+ e+   ++
  gi|2240501   324 ---------GFILDkddrrLLSYKDgkiNIENEEEKEEEEEGEEEDNENE 364  

                   svndGtdlkqkKeavLkddEneDDdLGAELE.DkeGeeDdEeDedEESDa
                    ++         e   +d E++  d   +LE+D e e +  e ++     
  gi|2240501   365 EESQ-------EESASEDGEDDAADGHSDLEsDLESEGEAAENKGDK--- 404  

                   EldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti
                         +  e e++   +  +k +   K                 +p+t+
  gi|2240501   405 ----KHKANENESENVEKLDPKRE-AAKS---------------ELPYTF 434  

                   dcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsv
                     P ++e +  Ll +   e+  +I eRI k++hp L+ +N K kl+K+  
  gi|2240501   435 AVPESYETFKSLLTGRTIEQQLIILERIQKCNHPSLAVGN-KAKLEKLFG 483  

                   vLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaisls
                   +LL +I     +l+  d  +   +    kLv +L+ l q +Pe++  s  
  gi|2240501   484 FLLEYI----GELATMDLPE---LRTIDKLVLPLYNLCQMFPEAASDSIK 526  

                   eellevikelaeey.kknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvT
                     l++    l e +++k     +P l++L+++k+v+llF+TSDf H+VvT
  gi|2240501   527 FILRDAAHDLEEVIeVKG-RATFPGLDTLIYLKIVSLLFPTSDFWHPVVT 575  

                   PalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalq
                   Pa++ m++ L ++++ +l+d+ +Glf++ ++L+++s S+R+vPe++++l 
  gi|2240501   576 PAFMYMSQLLTKCRIATLQDVIKGLFICCLFLEYVSLSRRFVPELINFLL 625  

                   qiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestlle
                   + L+  + p      ++    t   +   +  k L l+ +  + ++   e
  gi|2240501   626 GVLH-ISLP-----KNQAQGYTVVHP-FTPVGKNLELLLVCDKEDLKSWE 668  

                   pqrLslaDLVtqti.teefpvdalrsSlLliKEvleLvEeiveiyyklqA
                    q+ +   +Vt   +t        r S L       L+      y +l++
  gi|2240501   669 KQNVP-LSMVTRLKeTSRTEINHTRLSCLAM--CFDLIKKSAALYESLPS 715  

                   FiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKP
                   F EI+ P+  LL +     ++pek ++e   +a++ +e +         P
  gi|2240501   716 FHEIMHPVRILLTQHMPVNEYPEK-MQEWYHSALKELENKVK----HYTP 760  

                   LAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklK
                   L   ++KPv +    PK   + +  R    s     k   e++ L  ++K
  gi|2240501   761 LICEKKKPVPLKQYTPKIVKVLEFGRKQAGS-----KKEQERKQLIQRHK 805  

                   rEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl
                   rE KGAiRE+RKD +  ar  l E    d +r  K+k +   l +qeg+ 
  gi|2240501   806 RELKGAIREIRKDNQYLARMQLSEIMERDAARKRKVKELLGSLATQEGEW 855  

                   <-*
                      
  gi|2240501     -     -    

gi|114592956|ref|XP_001151808.1|: domain 1 of 1, from 19 to 847: score 538.4, E = 8.7e-159
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1145929    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1145929    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1145929   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1145929   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1145929   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1145929   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e+Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1145929   282 EQERLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1145929   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1145929   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1145929   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1145929   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1145929   482 --GDLATDDPPD---LRVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1145929   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1145929   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1145929   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I  P
  gi|1145929   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAITGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                     aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1145929   715 LRALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   + +  R  + s     ke  e++ L +k+KrE KGA+
  gi|1145929   760 PVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAV 804  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+RKD +F ar  l E    d er  K+k + n l +qeg+    
  gi|1145929   805 REIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    847  

gi|158259339|dbj|BAF85628.1|: domain 1 of 1, from 19 to 847: score 537.3, E = 1.8e-158
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1582593    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1582593    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1582593   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1582593   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1582593   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1582593   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1582593   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1582593   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1582593   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1582593   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1582593   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1582593   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1582593   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1582593   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1582593   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|1582593   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                     aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1582593   715 LRALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   + +  R  + s     ke  e++ L +k+KrE KGA+
  gi|1582593   760 PVPLKLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAV 804  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+RKD +F ar  l E    d er  K+k + n l +qeg+    
  gi|1582593   805 REIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    847  

gi|156405559|ref|XP_001640799.1|: domain 1 of 1, from 9 to 848: score 533.9, E = 1.9e-157
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +   +++K+ A +k+    NPF+v+v+k K+ ilGr   k K+++G 
  gi|1564055     9    SAAKKAAKRNAQQKTV-TNNPFEVHVNKQKYEILGR---KMKHDRGL 51   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka  kR +Tl  e+k+knK + f+DkR+GE++ + +     E+K
  gi|1564055    52 PGVSRSKAMKKRQKTLLTEYKQKNKANIFVDKRFGENDAEMT----LEDK 97   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + Rf+ E+  Q+  +K   ynl       ee++++g s     l  + +
  gi|1564055    98 LMQRFTIEK--QRHHAKAGIYNLE-----EEELTHLGHS-----LGDVGK 135  

                   lgeeLsdddELadeaLDkdflalkrF...eeeDAeaeeeqrGAkKsKkEV
                    ++ +  d+E   ++  +   ++++F  +     ++ e  +G + s kE+
  gi|1564055   136 FDDVRLSDEEDQEDEKNVQDAHFGGFlmkATKQESNRENEEGKHRSRKEI 185  

                   meEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKs
                   meE++aKSKl K Er+ +K e   l++ LD   k + s l+   +     
  gi|1564055   186 MEEVVAKSKLKKHERQMAKAESSNLTETLDQDWKEIRSMLSFRDPH---- 231  

                   GiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLr
                     K++  a    D+ YD+ +kE+ fe  ++ + ++KT E +A++E e+L 
  gi|1564055   232 -HKTEVKA----DD-YDIAVKELAFELKGKATNKLKTDEQIAKEEQERLS 275  

                   eLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE.ED
                    LE eR++RM++      ++          k+k+ S+dDL+Dsfs+ ++D
  gi|1564055   276 RLEAERIRRMRGLPP---EDS---------KPKHKSADDLGDSFSIQtDD 313  

                   KPKfGfiedlleREDNvdNeE..ddEdddeeaedsdDddsvndGtdlkqk
                   +    ++++        + eE+ ++E     a  sd+    +d       
  gi|1564055   314 RISVSYWDGKIN---LPEGEEtlEYEWLGKKAGKSDG----SD------- 349  

                   KeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKed.
                          d + D d G E+ D++  eD+  D+d +   E d  +dL  d+
  gi|1564055   350 -------DGDKDGD-GEEIADES-GEDEDDDDDIS--GEDDAGSDLDSDp 388  

                   eaqplkge.aikasvkeKANm....KKsadTiPASLdrsipFtidcPkth
                   e++ + +   i++  k K  + ++ KKs++    +  + +pFt+  Pk++
  gi|1564055   389 ESADEDEQvEISNAKKHKKDLmssvKKSSSV---AAKKELPFTFNAPKNY 435  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                    e++  ++k   +D  +I+eRI  ++hpK+ +eN K+k++ F ++LL ++
  gi|1564055   436 SEFTSMISKWKRDDALTIIERIKACNHPKILPEN-KSKMEIFFSILLEFM 484  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                   KDL       + +k       +kL+ +L+ +aq  P    +     l++ 
  gi|1564055   485 KDLL--TECPPDIKT-----VNKLTRHLFDIAQHSPVNTSRVVQGFLRKA 527  

                   ikelaeeykkn.EhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllm
                    +++ e+    +  +k+P l++L+ + L+  lF+TSDf+H V TPa+  +
  gi|1564055   528 QSQFTEQLDCTgGKGKFPGLDTLMMLPLITVLFPTSDFKHSVCTPAMVYI 577  

                   aevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftl
                   ae L +s+v+   d+ +GlfL+s VL+f   SkR+vPe +++l +  + l
  gi|1564055   578 AELLAQSRVRCITDVLKGLFLCSTVLEFIGVSKRLVPEAINFLCGTFY-L 626  

                   lvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                      K       + P  F        +    l+ + +    t ++  + s 
  gi|1564055   627 ASDKTSETSHLLMP--FKAK--SKWSD---LLKIQTDENATVIKEAKVSI 669  

                   aDLVtqtite.efpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIfl
                    +     ++ ++++  + r S L    +l    e  e y+ l+AF E f 
  gi|1564055   670 IE----ALSDgDLSNTQTRVSVLHL--ALRITSELCELYKDLPAFKETFS 713  

                   PIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeH
                   P+l  L+r++  + +p   +ke + + v  +e l     + r  LAlq +
  gi|1564055   714 PVLCHLHRIPI-KTYPAF-VKELHSSLVARIEALSG---QVRSHLALQTR 758  

                   KPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGA
                   KP  I + ePKF E yD K    k S    k   e  KLk k KrE KGA
  gi|1564055   759 KPQPIKTFEPKFDEHYDIKSKKNKGS----KKANEDQKLKYKFKREFKGA 804  

                   iRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   iRE RKD++F ar++ +E+   d er  K+k i+  l+ q+ +    
  gi|1564055   805 IREVRKDSQFLARQKHQEQMDRDAERMRKVKQIEHMLSNQQAET    848  

gi|156056817|ref|XP_001594332.1|: domain 1 of 1, from 34 to 899: score 530.9, E = 1.5e-156
                   *->keedreeKKK...AvakiqkefNPFdvkvakr.KFdilGrsKt.kvK
                      +   +e K K++ A   i+ +fNPF+++ ak +KF +    Kt   +
  gi|1560568    34    NGANKEKKIKrsvALSGIRDQFNPFEIRQAKApKFEVTSN-KTlSGR 79   

                   geeG..kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsG
                   + +G +kPGV R+ aee R++Tl  e + +n+ g++iDkR+GE+++    
  gi|1560568    80 ISKGikKPGVARGLAEENRRKTLLVEMQSRNRVGGIIDKRFGENDPSMA- 128  

                   DqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDve...edGdrggs.
                       E+KMleRf+ E+  Q+    ++   ++  lED+e ++e++++g+s 
  gi|1560568   129 ---PEDKMLERFTQEK--QRG--HKNSSAFD--LEDDEvsgELTHMGQSl 169  

                   .....SvKDDlD..sleelgeeLsdddELadeaLDkdflalkrFeeeDAe
                   + +++ ++DD+D+++le+++ +  + dE+  +   k++  ++  + + +e
  gi|1560568   170 sldgpTIRDDFDdeGLELSDADDHESDEERQAR--KRRRGSNSEGSDEDE 217  

                   ..aeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNf
                   +++  + r  kKsK+EVm+E IaKSK  K Er+++Ke  eDl+++LD+ +
  gi|1560568   218 egNSLPER--KKSKQEVMKELIAKSKMHKYERQAAKEDDEDLREELDKEM 265  

                   kdLlsll..ameklt.......sRKsGiKkpreaked......tDaeYDl
                     +  ll+++  k+ ++++ +++   G+  +r a  +++++ ++ +eYD+
  gi|1560568   266 SGIHELLrgMAAKPPppppappADIPGMNPERIALMNggdrakLEKEYDI 315  

                   llkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEled
                     + M  +kR +P++R KTe+E+  +E  +L eLE  Rl+RMe+  E++d
  gi|1560568   316 RMRQMAQDKRSQPTERSKTEDEKMEQESRRLKELEAKRLRRMEGVTEDSD 365  

                   gEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdN
                    Ee         k++  + + +      EE+   +G + ++  R    + 
  gi|1560568   366 DEE-------DNKPRRVGDEEEEE----EEEEEDYGLGSGIKTRPSAAEL 404  

                   eEddEd....ddeeae...dsdDddsvndGtdlkqkKeavLkddEneDDd
                   + ddEd+   dd++ ++++d d  ++++d            ++d ++D +
  gi|1560568   405 GADDEDdfiiDDDLVAsgsDIDESEGESD------------EEDGESDNE 442  

                   LGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg.eaikasv
                         D e + + + +  EE                + l g  a+  +v
  gi|1560568   443 ------DDE-FLE-GLLTEEE------------AKRPEFLTGaNAPLPEV 472  

                   keKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIV
                      +  K            ++++t+ cP +heelle   + +l D p++V
  gi|1560568   473 EMPT--KNGVNG-------DLAYTFACPQSHEELLEITRGIALLDLPTVV 513  

                   eRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfq
                   +RI+ +hhpKL  eN K kl++Fsv L  hI   +  l++Q+   +  f 
  gi|1560568   514 QRIRALHHPKLNSEN-KGKLGNFSVSLISHI--SY--LANQAQQPP--FS 556  

                   LLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl
                    Le    + ++la+ ++   a  ++  l e+    a + k          
  gi|1560568   557 VLENIIRHIHSLAKTFSLEIANAFRRHLDEINQSRALSLKAG-------- 598  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                    dLv +  +g +F+TSD  H VvTPa+l+m  +L +   ++l+d  +G++
  gi|1560568   599 -DLVILTAIGTIFPTSDHFHQVVTPAILTMGRYLGQKIPQTLSDYTMGAY 647  

                   LvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerd
                   L+s+ L++q+ SkRyvPeVv +++  L   l p      l   P+ F   
  gi|1560568   648 LCSLCLQYQRLSKRYVPEVVGFIENTLC-ALAP----SKLAKIPGCFPYH 692  

                   RLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsS
                         +  P+  +   k    +   +   +D     +  e + d+ +sS
  gi|1560568   693 ------E--PKSSVRIEKVTESD--RQIAFYD----CVALESSADDEESS 728  

                   ...lLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpek
                   +  lL    ++  +    + +   +AF E+f P+l+ L  +++ +s  +k
  gi|1560568   729 kaaLLEA--TIKILNASADLWTDKSAFTEVFEPVLTILKHLGS-KSCRSK 775  

                   Rlke.......klldavelveKltedakkerKPLAlqeHKPvaIrllePK
                    l+e++++  +k  ++ +    l+      r PL l  HKP+aI +  PK
  gi|1560568   776 -LSEssqtlirKSRSKFQTMLQLAH---LARRPLELHHHKPLAIKTSIPK 821  

                   FEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFv
                   FE  y    +Pdk  yDpD+eR+e +KLka +K+E+KGA+RElRKD+ F+
  gi|1560568   822 FEDSY----NPDKH-YDPDRERAETAKLKAEHKKERKGAMRELRKDSNFI 866  

                   arlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ar+ l +k  kd +   Kmk++ +e+q +eg +   
  gi|1560568   867 ARESLRQKKEKDAAHEKKMKRLIAEIQGEEGKE    899  

gi|66550520|ref|XP_397160.2|: domain 1 of 1, from 19 to 826: score 530.2, E = 2.6e-156
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k + r eK           NPF+v+ +k K  +lG+   k+K ++G 
  gi|6655052    19    KRDRRNEK---------SLNPFEVHINKIKQNVLGK---KDKTDKGL 53   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRaka+ kRk Tl +e+k knKs+ f+DkRiGE+n        eEeK
  gi|6655052    54 PGVSRAKAIKKRKETLLQEYKLKNKSNLFLDKRIGEKNLFMN----EEEK 99   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    l+Rf +Erm   +  K++ ynln    D e +++ g++     l+++e+
  gi|6655052   100 ALARFAAERMKAHK--KQSIYNLN----DEEILTHKGQT-----LEEIEK 138  

                   lgeeLsdddELadea....LDkdflalkrFeeeDAeaeeeqrGAkKsKkE
                    ++ +sdd+  +de ++++LD  f   ++F++   +  e ++    s k 
  gi|6655052   139 FDDPRSDDEYSDDENrtgkLDNKFVSEAHFGGGILSKSESGK----SRKD 184  

                   VmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRK
                   +++E Ia+SK +KaE++K +e   Dl++kLD    dLl+  + + +    
  gi|6655052   185 IIDELIAESKKRKAEKQKIREQTIDLTEKLDSEWRDLLPIMSATNKD--- 231  

                   sGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekL
                       ++  +k   D+ YD+ ++E+ fe  + Psd++K eE   ++E+ekL
  gi|6655052   232 ---IEEETIKMKVDD-YDIAVRELKFEAKGMPSDKLKSEEDTIKEEKEKL 277  

                   reLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEED
                   ++LE  Rl RM++ +      e           k+ S+dDLdD       
  gi|6655052   278 EALEADRLARMKGLIN-NTNNE----------IKHKSADDLDD------- 309  

                   KPKfGfiedlleREDNvdNeEd..dEdddeeaedsdDddsvndGtdlkqk
                       Gfi d+ eR    +  E++     +ee  +   +d  +d       
  gi|6655052   310 ----GFIGDIKERKKIKNFTESklNKNFNEEVSENSEEDNLSD------- 348  

                   KeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKede
                       Lk+ E +  d   E  Dk        + + E    l    +  e  
  gi|6655052   349 ----LKESEYSSED---EKNDKNDKKSKANLNVLE----LNSNIKIQEIR 387  

                   aqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleL
                      lk + i       A              + +p+ ++ P ++eel e 
  gi|6655052   388 DDLLKRKEIMEN----A-------------RKELPYVYKSPENFEELQEF 420  

                   lkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfED
                   l     +   +I+ RIik++h  L   N Kekl ++  + Lqh+   +  
  gi|6655052   421 LQNRNADYQSIIIDRIIKCNHWSLNSIN-KEKLSNLFLFILQHL-NNH-- 466  

                   lseQdikknLN.fqLLekLveaLielaqelPeklaislseellevikela
                   + e d+ + +  fq   +L + L+ la ++Pe        ++  +ike+ 
  gi|6655052   467 AMEDDVESVVKcFQIVDRLSPFLYDLAHLNPEN----TKFVVQAIIKEKH 512  

                   eeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsr
                   +e+ kn  +kyP l++L+fFkLv+l+F+TSDfrH++ TP+l++m++ L r
  gi|6655052   513 KEFEKN-KKKYPYLDTLIFFKLVSLIFPTSDFRHPITTPCLIFMSQILFR 561  

                   spvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRD
                   + v    dI++Gl +++++L++   SkR+ P V+++l +i++  + pK  
  gi|6655052   562 CQVKNKVDISKGLLICTLILEYTVLSKRFPPSVINFLRGIIY-ISTPKCL 610  

                   VellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtq
                   +  +   P +F +   + l+  L ld + ++ ++  + +      DLV  
  gi|6655052   611 IQGIKMIP-PFKKT--GELSNLLILDEDQTNLDIDPINMLMKA-SDLVDG 656  

                   titeefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLs
                    +   f+ +al + + l  E  +  E   ++y           PIl LL 
  gi|6655052   657 PLDDNFKIRALLTAINLLCEFKNHFEKLETVYSIFE-------PILKLLE 699  

                   ryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrl
                   +     ++p k +k+  +   + +  l     k+   L   ++KP+ +rl
  gi|6655052   700 ANFF-DKYPFK-VKKCVERLRKELKELKN---KKLEYLVVEKKKPKPLRL 744  

                   lePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKD
                    eP+ E  yD K+   +s     ke++e  KL++k K+E KGAiRE+R+D
  gi|6655052   745 YEPRIETIYDSKKHKTMS-----KEKAEKEKLLHKYKKEMKGAIREIRRD 789  

                   akFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                     F a lR+k++ + d er  K+k i  e+  q+ +l   
  gi|6655052   790 RMFLAKLRIKQQIKNDEERKRKVKEIFGEAAMQQSEL    826  

gi|149642709|ref|NP_001092466.1|: domain 1 of 1, from 21 to 859: score 529.7, E = 3.7e-156
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +  +r              NPF+vkv++ KF +lGr   k ++++G 
  gi|1496427    21    GGRARPNP-----------NPFEVKVNRQKFQVLGR---KTRHDVGL 53   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a++kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1496427    54 PGVSRARALQKRTQTLLKEYKERDKSNVFRDKRFGEYNSSIS----PEEK 99   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q++  K++ ynln     +ee+++ g+s     l  +e+
  gi|1496427   100 MMKRFALEQ--QRQHEKKSIYNLN----EDEELTHYGQS-----LADIEK 138  

                   lgeeLsdd.dELadeaLDkdflalkrFeee.....DAeaeeeqrGAk..K
                     +  + d+d +   aL + ++a  +F++ +++ ++  a+++  G  ++K
  gi|1496427   139 HNDIVDSDsDTEGRGALSAELTAT-HFGGGsgpvpGKAAQQPSGGEEppK 187  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   s +E +eE Ia SK  K Er++++e    l++kLD   k ++ lla   +
  gi|1496427   188 SRRELIEELIARSKQEKRERQAQREDALELTEKLDQDWKEIQALLACKTP 237  

                   tsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkE
                   +s   G K+    k+ +Da YD  ++E+ fe  A+Ps R KTeEElA +E
  gi|1496427   238 KSESGGGKE----KPKPDA-YDMMVRELGFEMKAQPSNRMKTEEELAREE 282  

                   aekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfs
                    e+Lr LE eRl+RM +  E    ++        k++k+ S+dDL D   
  gi|1496427   283 QERLRRLEAERLRRMLGRDE----DA------HSKRPKHLSADDLND--- 319  

                   VEEDKPKfGfiedlleR......EDNvdNeEddEdd....deeaedsdDd
                           Gf +d  +R+  + ++  ++ eE+  +d++++d++ e+++  
  gi|1496427   320 --------GFVLDTDDRrllsykDGKMNVEEEPSGDssggDSGEEEEEKG 361  

                   dsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDa
                   ++ + G+ +         d E + D      ED      d+    E+   
  gi|1496427   362 EGWSEGGPEDSDSPDGHSDLESDADS-----EDAR--SADGLVGRES--D 402  

                   EldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti
                    ++v   L  d   p +ge +       A     a          +p+t+
  gi|1496427   403 GVEVRAQLQGDQ-RPSPGERLPRD--DRA----AARA-------QLPYTF 438  

                   dcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsv
                     P + eel  Ll++ + eD  l+VeRI k++hp L+ +N K kl+K+  
  gi|1496427   439 AVPESCEELKSLLSGKSMEDQLLVVERIQKCNHPSLAVGN-KAKLEKLFG 487  

                   vLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaisls
                   +LL +I     Dl++ d      +    kLv +L+ l q +Pe +     
  gi|1496427   488 FLLEYI----GDLAVSDPPD---LGVIDKLVVPLYDLCQMFPESASDAVK 530  

                   eellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTP
                    +l++   e+           +P l+ L+++k+ g lF+TSDf H+V+TP
  gi|1496427   531 FVLRDAMHEMEGTVETTGRAAFPGLDVLIYLKIAGMLFPTSDFWHPVITP 580  

                   alllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqq
                   all +++ L ++pv+Sl+d  +Glf + ++L ++  S R++Pe++++l +
  gi|1496427   581 ALLCLSQLLTKCPVRSLQDAVKGLFVCCVFLDYVALSQRFIPELINFLAG 630  

                   iLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllep
                   iL+ +  p +      ++  +F     +  ++   l+ +    ++     
  gi|1496427   631 ILH-MATPNKQSQGYTLVH-PFRAL--GKNSE---LLLVSDEEDMATWQR 673  

                   qrLsla...DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklq
                     L+l   + L  qt te+  +++   S L     l Lv   v +y+ l+
  gi|1496427   674 RSLPLQwagGLKAQTETEANHTRL---SCLAL--CLALVRRCVLAYGTLP 718  

                   AFiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerK
                   +F  I  P  aLL         p + l+e   +++   e           
  gi|1496427   719 SFHDIARPLRALLTEHLATRCCPPT-LQELSRSVLTEMENQPR----HYR 763  

                   PLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkakl
                   PL   + KPv + l  P+   + +  R  +       +e  e+  L +k+
  gi|1496427   764 PLVCEKSKPVPLKLFTPRLVKVLEFGRKQGST-----REEQERRRLIHKH 808  

                   KrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegA
                   KrE KGA+RE+RKD +F ar Rl E    d er  K+k + n l +qeg+
  gi|1496427   809 KREFKGAVREIRKDNQFLARMRLSEIMERDAERKRKVKQLFNSLATQEGE 858  

                   l<-*
                       
  gi|1496427   859 W    859  

gi|73951769|ref|XP_536223.2|: domain 1 of 1, from 149 to 979: score 527.3, E = 1.9e-155
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                         +++         +   NPF+vkv++ KF +lGr   k ++++G 
  gi|7395176   149    PAGAQSGR------ARPNPNPFEVKVNRQKFPVLGR---KARHAVGQ 186  

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a++kR +Tl +e+k + Ks++f DkR+GE     s     EeK
  gi|7395176   187 PGVSRARAVQKRTQTLLKEYKERDKSNVFTDKRFGEYSSSMS----PEEK 232  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q++  K++ ynln     +ee+++ g+s    D++    
  gi|7395176   233 MMKRFALEQ--QRQHEKKSIYNLN----EDEELTHYGQS--LADIEKHND 274  

                   lgeeLsdddELadeaLDkdflalkrFeeeD.........AeaeeeqrGAk
                     ++ sd +E    +  + ++a+ +F++ ++  ++++ +  +e+e +   
  gi|7395176   275 IVDSDSDAEERGTLS--AELTAA-HFGGGGgllhkktlqQQGEDEEK--P 319  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                    s kE +eE IaKSK  K Er++++e    l++kLD   k ++ lla   
  gi|7395176   320 RSRKELIEELIAKSKQEKRERQAQREGALELTEKLDQDWKEIQTLLAHKT 369  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   ++         +  k+ +Da YD  ++E+ fe  A+Ps R KTeEElA++
  gi|7395176   370 PK----PENRDQKEKPKPDA-YDMMVRELGFEMKAQPSNRMKTEEELAKE 414  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e+L +LE  Rl+RM++  E+  g+         +k+k+ S+dDL D f
  gi|7395176   415 EQERLQKLEAARLRRMRG--EDMHGDS--------RKPKHLSADDLNDDF 454  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaed..sdDddsvndG
                     +++D+    + ++       v+ e + E  d e+e+++ +D   +n+ 
  gi|7395176   455 VLDkDDRRLLSYTDGKMS----VEEEQSREASDGESEEdhHEDPSDENL- 499  

                   tdlkqkKeavLkddEneDDdLGAELE.DkeGeeDdEeDedEESDaEldvl
                                 E +D d   +L++D+e eeD ++ + E         
  gi|7395176   500 -------------EESSDPDGHSDLDsDTETEEDCGRPDTEP-------- 528  

                   kdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkt
                              + + + +    KA  +  a          +p+t+  P +
  gi|7395176   529 --------RLAPQKRLANN-GHKA--REAARN-------ELPYTFAAPES 560  

                   heelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqh
                   +eel  Ll++   e   l+VeRI +++hp L+++N K kl+K+  +LL +
  gi|7395176   561 YEELKSLLSGKTMEEQLLVVERIKTCNHPSLAAGN-KAKLEKLFGFLLEY 609  

                   IKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseelle
                   +     Dl+  d      +    kLv  L+ l q +P  +  s   +l++
  gi|7395176   610 V----GDLATSDTPD---LGVIDKLVVQLYNLCQMFPDSASNSIKFVLRD 652  

                   vikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllm
                      e+  +        +P l+ L+++k+ g lF+TSDf H+V TPal  m
  gi|7395176   653 AMHEMEGSVEARGRVAFPGLDVLIYLKIAGMLFPTSDFWHPVTTPALVCM 702  

                   aevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftl
                   ++ L ++pv Sl d+ +Glf +  +L ++s S+R++Pe+v++l +iL+  
  gi|7395176   703 SQLLTKCPVLSLHDVVKGLFVCCMFLDYVSLSRRFIPELVNFLLGILY-I 751  

                   lvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                     p +      ++  +F     +  ++   l+ +    +        Lsl
  gi|7395176   752 ATPNKHGQGYTLVH-PFRAS--GKNSE---LLLVSDEEDTATWQRTGLSL 795  

                   ...aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEI
                   +    L  qt te+  +++   S L +   + Lv   v  y +l+AF  I
  gi|7395176   796 rwaSGLKAQTKTEANHTRL---SCLAV--CVALVKHCVLLYSSLPAFHDI 840  

                   flPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlq
                   + P  aLL         p   l+e   +++  ++       +   PL   
  gi|7395176   841 MRPLRALLTEHLANRTHPPE-LQELCQSTLSTLTNMGK-QSQRCRPLVCE 888  

                   eHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkK
                   + KPv +rl  P+   + +  R  + s     ke  e++ L +k+KrE K
  gi|7395176   889 KSKPVPLRLFTPRLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFK 933  

                   GAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   GA+RE+R+D +F ar  l E++  d er  K+k + n l +qeg+    
  gi|7395176   934 GAVREIRRDNQFLARMQLSETLERDAERKRKVKQLFNSLATQEGEW    979  

gi|261201764|ref|XP_002628096.1|: domain 1 of 1, from 37 to 889: score 527.2, E = 2.1e-155
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r     A + i+++fNPF++++  r+ KF    r    +  + 
  gi|2612017    37    GAANRIQRNAALQGIREQFNPFEIRAPARpaKFSSTSR---SDQDAP 80   

                   G.kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                   ++ PGV +  +e++Rk Tl +e + + K g  +D+R+GE+++  +     
  gi|2612017    81 RsRPGVTKSLGEQRRKETLLKEMQRRSKVGILLDRRFGENDPTMT----P 126  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggsSvKDD
                   Ee   eRf RE   Q +L K ++  +n  lED+ee+ +++++g++     
  gi|2612017   127 EERAAERFARES--QKKLKKESM--FN--LEDDEEemqLTHLGQT----- 165  

                   lDsleelgeeLsdddELadeaLD...kdflalkrFeeeDA..........
                   +    e  ++  +dd+ a+++ D++++      r+ eeD+ ++  +++++
  gi|2612017   166 ITFDKENKDDFEEDDLNASDE-DgesEKARKRRRNAEEDDmeglagdsee 214  

                   eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfk
                   e++ e++   KsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+   
  gi|2612017   215 EGQPERK---KSKNEVMKELIAKSKFHKYERQKAKEDDDDLRASLDKGLP 261  

                   dLlsllamekltsRKsGiKkpre..akedt....................
                    +  +++m  ++      K + e+ +k+d++ + ++++    +++++++ 
  gi|2612017   262 EI--FEMMRGVK------KPEPEplPKPDLtatmnpdraallngkdrdea 303  

                   DaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee
                   D+eYD  lk M  +kRA+P dRTKTeEE+A +Eae+Lr LE eRl+RM++
  gi|2612017   304 DKEYDQRLKQMTYDKRAKPLDRTKTEEEKAEEEAERLRQLEKERLRRMQG 353  

                   teEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleR
                      ++ +Ee             ++  D dD +s  +D   fG  +     
  gi|2612017   354 ATVDSSEEE-----------DNGGDKDMDD-DSEPDDAKAFGLAQPSNMP 391  

                   EDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdL
                   E  v+  Edd  +d+   +sd +   ++                +e D  
  gi|2612017   392 ELGVE-DEDDFIIDSDLVESDSEAELSL----------------DESDL- 423  

                   GAELEDkeGeeDdEeDedEES......DaEldvlkdLKedeaqplkgeai
                    A   D+e  e +EeD+ +  +   ++DaE d          +   ge +
  gi|2612017   424 -ASSADEE--ESEEEDDEFIGglvlppDAEADKRP-------ATTNGETP 463  

                   kasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDk
                    a+    A             +  ++Ft++cP +he +l+ ++    eD 
  gi|2612017   464 TAT----A-------------NNNLAFTYPCPENHEHFLQIVENTKIEDL 496  

                   plIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikkn
                   p++V+RI+ +hhp L+ +N K+kl  Fs vL qh    +  l++Q+   +
  gi|2612017   497 PTVVQRIRALHHPRLHIDN-KSKLATFSKVLVQHT--VY--LANQPDHPP 541  

                   LNfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhik
                     f  Le L  + +++a+  Pe+ a  +++ l+e+          +    
  gi|2612017   542 --FAVLENLLRHIHSMAKAQPEAVASAMRNHLREMSES------RP---- 579  

                   yPSl..kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkd
                    ++l ++dLv +  v+ +F+TSD  H+VvTP++l ma +L +s +  l  
  gi|2612017   580 -LELlpGDLVILTGVATIFPTSDHFHAVVTPSMLAMARYLGQSNIANLGN 628  

                   IaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitP
                   Ia G++++++  ++q   kRy+Pe ++ +   L   l p   V  l   P
  gi|2612017   629 IATGAYIATLCIQYQALAKRYIPEFMNYVLNVLC-ILAPSEPVHTLGFFP 677  

                   LtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpv
                      +     +l +   +  l ++k  t+l +   s+aD            
  gi|2612017   678 IRQAST---PLCLTPSKFPLTTIKKPTFLDILATSPAD--------GAEQ 716  

                   dalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrys..lke
                    al+ Sl +    ++L+  + + + + +AF  If P    L  ++++l  
  gi|2612017   717 EALKLSLIST--FISLLDQAADLWSSKSAFYDIFAPANRVLKYLTksLNN 764  

                   slpekRlkekll...davelveKltedakkerKPLAlqeHKPvaIrlleP
                   + p + l   l ++ d+++++ K  +     r PL l +H+P+aI +  P
  gi|2612017   765 KTPRT-LYDQLQrtcDKLQALLKQSD---LGRRPLLLHNHRPLAIKTAIP 810  

                   KFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakF
                   KFEE +    +P    yDpD+eR+elnKLka +KrE+KGA+RElRKDa F
  gi|2612017   811 KFEESF----NPSRH-YDPDRERAELNKLKAEHKRERKGAMRELRKDANF 855  

                   varlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +ar+ l Ek+ kd e+  K +++v+e+q +eg +   
  gi|2612017   856 IARESLREKREKDAEYERKYRRLVAEIQGEEGRE    889  

gi|225558305|gb|EEH06589.1|: domain 1 of 1, from 37 to 889: score 527.0, E = 2.3e-155
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r     A + i+++fNPF++k+  r+ KF    r        +
  gi|2255583    37    GAASRIHRNAALQGIREQFNPFEIKAPTRpaKFNSVSR--SNQDAPR 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e + + K g  +D+R+GE+++  +     E
  gi|2255583    82 SRPGVTKGLGEQRRKETLLKEMQRRSKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e   eRf RE   Q+rL K ++ nl D +E v  ++++g++     +   
  gi|2255583   128 ERAAERFARES--QRRLKKESMFNLEDDEEEV-QLTHLGQT-----ITFD 169  

                   eelgeeLsdddELadea...LDkdflalkrFeeeD......AeaeeeqrG
                    e++++ ++dd+  ++++++L+k ++     ee+D ++  +++ ee q  
  gi|2255583   170 AESRDDFQEDDLNVSDEegnLEKIRKRRRTAEEDDmeglaeDSEEEGQPE 219  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                    kKsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+    +  +++m
  gi|2255583   220 RKKSKNEVMKELIAKSKFHKYERQKAKEDDADLRASLDKGLPEI--FEMM 267  

                   ekltsRKsGiKkpreakedt......................DaeYDlll
                     ++      K + e+ + ++   + ++++    +++++++ D+eYD  l
  gi|2255583   268 RGVK------KPEPEPLPQPdlvatmnpdraallngkprdeaDKEYDQRL 311  

                   kEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgE
                   k M  +kRA P dRTKTeEE+A +Eae+Lr LE eRl+RM++ + +  +E
  gi|2255583   312 KQMTYDKRANPVDRTKTEEEKAEEEAERLRQLEKERLRRMQGAGDDLSEE 361  

                   eEiGGEESvkklkvrSvdDLdDsfsVEEDKPK.fGfiedlleREDNvdNe
                                  + +D  D  + E D  K fG  +     E  v+  
  gi|2255583   362 Q-----------DSNGEEDVED--NSEPDDAKaFGLAQPKSIQEFAVE-D 397  

                   EddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDk
                   Edd  +d    +sd               ea L  dE +     A  E +
  gi|2255583   398 EDDFIIDRDLVESDS--------------EAELFLDESDMAS--ASTEEE 431  

                   eGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKs
                   + e +d e  +        vl          ++ ++++ +          
  gi|2255583   432 S-EAEDDEFIGGL------VLPP------GMEVDKGPSTT-------NGE 461  

                   adTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhp
                   ++T  A  +  ++Ft++cP++he +l+ +k+  +eD p++V+RI+ +hhp
  gi|2255583   462 SST--ALTNNNLAFTYPCPRSHEHFLQIIKDTKTEDLPTVVQRIRALHHP 509  

                   KLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaL
                    L+ +N K+kl  Fs vL qh    +  l++Q+   +  f  Le L  + 
  gi|2255583   510 RLHSDN-KSKLATFSQVLVQHT--VY--LANQPNHPP--FAVLENLLRHV 552  

                   ielaqelPeklaislseellevikelaeeykknEhikyPSl..kdLvfFk
                   +++a+  Pe+ a  ++  l+e+          +     ++l ++dLv + 
  gi|2255583   553 HSMAKAQPEAVASAMRDHLREMSET------RP-----LELlpGDLVILT 591  

                   LvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLk
                    v+ +F+TSD  H+VvTP++l ma +L +s +  l  Ia G++++++  +
  gi|2255583   592 GVATIFPTSDHFHAVVTPSILAMARYLGQSNITNLGNIATGAYIATLCIQ 641  

                   fqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslek
                   +q   kRy+Pe ++ +   L   l p    e l + PL        +l +
  gi|2255583   642 YQTLAKRYIPEFMNYVLNGLC-ILAPIEPKETLGLFPLRQPSV---PLHL 687  

                   GLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEv
                           +  e+ l  + +L   D+     t       l+ Sl +    
  gi|2255583   688 --------TASELPLTHIRKLTFWDVLANSSTDSREQETLKLSLIST--F 727  

                   leLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekRlk...ek
                   + L+  + + + + +AF  If+P    L  +++sl  + p+  l+++ ++
  gi|2255583   728 ITLLDHAADLWSSKSAFHDIFVPANRVLKHLnhSLNNKFPSA-LSdqlQR 776  

                   lldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPd
                   +ld+++ + K  +     r PL l +H+P+aI +  PKFEE +    +P 
  gi|2255583   777 ILDKLQVLLKQSD---LARRPLLLHNHRPLAIKTAIPKFEESF----NPS 819  

                   ksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakd
                      yDpD+eR+elnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+ kd
  gi|2255583   820 RH-YDPDRERAELNKLKAEHKRERKGAMRELRKDANFIARESLREKREKD 868  

                   qerhEKmkkivnelqeqegAl<-*
                    e+  K +++v+e+q +eg +   
  gi|2255583   869 AEYERKYRRLVAEIQGEEGRE    889  

gi|291245101|ref|XP_002742430.1|: domain 1 of 1, from 17 to 869: score 526.9, E = 2.6e-155
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +    + K         + NPF+++ +k K  +lGr   k K+++G 
  gi|2912451    17    NTKSNSGK---------KTNPFEIRINKQKHVVLGR---KTKHDKGL 51   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG  R ka+ kRk Tl  e+k+++Ks+  +D+R GE + +L+     EeK
  gi|2912451    52 PGLARSKALAKRKDTLLNEYKQRHKSNKLVDRRLGEGDVLLT----PEEK 97   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + Rf  E+  Q    K + ynln    D+ee+++ g+s     l  +e+
  gi|2912451    98 IMQRFAFEK--QKHHEKASVYNLN----DDEELTHYGQS-----LAHIEK 136  

                   lgeeLsdddELadea..LDkdflalkrFee....eDAeaeeeqrGAkKsK
                       L  ddE + e ++LD+   a  +F++  ++  + + +      Ks 
  gi|2912451   137 FENPLESDDEDDEEMgrLDATYVAEEHFGGfltrKKDDNKDNSM---KSR 183  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklts
                   kE +eE Ia SK  K Er  eKee   l++kLD   k +  lla  k   
  gi|2912451   184 KELLEERIAISKKEKYERKTEKEETIELREKLDSDWKEISGLLAGSKRN- 232  

                   RKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEae
                        K++  +     +eYD  ++E+  e  A+ sdR+KT +ElA  E+e
  gi|2912451   233 ----RKEEALIRKSEVDEYDMAVRELKYERKAKASDRLKTADELARDERE 278  

                   kLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE
                   +L++LE  R +RM++  E e++           k+ ++S+d L D  +V 
  gi|2912451   279 RLEKLEADRQRRMKGISE-EEEPD---------KPEHISADALED--NVA 316  

                   ...EDKPKfGfiedlleREDNvd..........NeEddEdddeeaedsdD
                    ++ +K    + e+ l     vd+  +  + ++N  d  ++  e+ d++ 
  gi|2912451   317 lprKEKFHLSYKEGKLLLPAGVDslyslanvskNNKDVSGEENESVDEEE 366  

                   ddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDd...EeDedE
                      +nd          v  dd   DDd      D e ee+++  E D+d 
  gi|2912451   367 ---END--------KFVCNDDSAADDD------DDE-EEEEnaaEDDSDG 398  

                   ESDa....EldvlkdLKede...aqplkgeaikasvkeKANmKKsadTiP
                   E D++ + E d  +d  +d ++++q  k+e  k+       +K   +   
  gi|2912451   399 E-DSgadiESDESSDIDDDDdgtSQVIKEEDEKNK------LKMIREA-- 439  

                   ASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkee
                       + +p+t++ P +++el++ + ++++    lI+eRI+k+hhp L+e+
  gi|2912451   440 ---KKELPYTFEAPDSYDELVAIIGGHSTNNQLLIIERIRKCHHPSLAEG 486  

                   NRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaq
                   N  ekl+ + + LL ++     Dl+     k   + L  kL  +L+el q
  gi|2912451   487 N-SEKLERLFALLLEYL----GDLACERPPK---MGLIDKLIRHLYELCQ 528  

                   elPeklaislseellevikelaeey.....kknEhikyPSlkdLvfFkLv
                     P k    + e+    i e +ee+++  +kkn   kyP l+ L++FkLv
  gi|2912451   529 NSPIK----AAETMQASIVERYEEFddlceKKN-KRKYPGLDMLLYFKLV 573  

                   gllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfq
                   ++lF+TSDfrH VvTP  l+m++vL  +      d+a Glf ++++ +++
  gi|2912451   574 SILFPTSDFRHSVVTPTVLFMSQVLTHCQPTCCHDVAVGLFVCNLFFQYV 623  

                   siSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGL
                   s SkRyvPeVv+ l + Lf l+v K   +l  + P +F       ++   
  gi|2912451   624 SLSKRYVPEVVNYLYGVLF-LSVQKSNSKLYPVIP-PFKPF--SKYSH-- 667  

                   PldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvle
                     ++l      +   + r sl D+          +d +r S+ +    l+
  gi|2912451   668 -ILVLEDTEKTSQKDVARISLSDMFADNSQDNCNSDSFRVSIMNT--CLS 714  

                   LvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavel
                   L+ e+ e y  l+ + EIf  Il  Ls +    +++   +k k  +   l
  gi|2912451   715 LIHEFAELYQDLPCYKEIFTFILSILSELEV-DKYLDQ-IKNKVTNLQSL 762  

                   veKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpD
                   ++       k r  L   ++KP +I l ePK  E y    ++d +     
  gi|2912451   763 LSNQDK---KSRDFLRREKKKPQSIKLYEPKIIEDY----NLDTKRKAQS 805  

                   keRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKm
                   ++  e  KL  k++rE KGAiRE+RKD++F ar++++E++  d er  K+
  gi|2912451   806 RTQNEKQKLISKHRREMKGAIREIRKDTQFLARQKIEEQLERDVERKRKV 855  

                   kkivnelqeqegAl<-*
                   k +++ l +qeg +   
  gi|2912451   856 KELYQMLGTQEGDF    869  

gi|239611906|gb|EEQ88893.1|: domain 1 of 1, from 37 to 889: score 525.9, E = 5.1e-155
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r     A + i+++fNPF++++  r+ KF    r    +  + 
  gi|2396119    37    GAANRIQRNAALQGIREQFNPFEIRAPARpaKFSSTSR---SDQDAP 80   

                   G.kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                   ++ PGV +  +e++Rk Tl +e + + K g  +D+R+GE+++  +     
  gi|2396119    81 RsRPGVTKSLGEQRRKETLLKEMQRRSKVGILLDRRFGENDPTMT----P 126  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggsSvKDD
                   Ee   eRf RE   Q +L K ++  +n  lED+ee+ +++++g++     
  gi|2396119   127 EERAAERFARES--QKKLKKESM--FN--LEDDEEemqLTHLGQT----- 165  

                   lDsleelgeeLsdddELadeaLD...kdflalkrFeeeDA..........
                   +    e  ++  +dd+ a+++ D++++      r+ eeD+ ++  +++++
  gi|2396119   166 ITFDKENKDDFEEDDLNASDE-DgesEKARKRRRNAEEDDmeglagdsee 214  

                   eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfk
                   e++ e++   KsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+   
  gi|2396119   215 EGQPERK---KSKNEVMKELIAKSKFHKYERQKAKEDDDDLRASLDKGLP 261  

                   dLlsllamekltsRKsGiKkpre..akedt....................
                    +  +++m  ++      K + e+ +k+d++ + ++++    +++++++ 
  gi|2396119   262 EI--FEMMRGVK------KPEPEplPKPDLtatmnpdraallngkdrdea 303  

                   DaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee
                   D+eYD  lk M  +kRA+P dRTKTeEE+A +Eae+Lr LE eRl+RM++
  gi|2396119   304 DKEYDQRLKQMTYDKRAKPLDRTKTEEEKAEEEAERLRQLEKERLRRMQG 353  

                   teEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleR
                      ++ +Ee             ++  D dD +s  +D   fG  +     
  gi|2396119   354 ATVDSSEEE-----------DNGGDKDMDD-DSEPDDAKAFGLTQPSNMP 391  

                   EDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdL
                   E  v+  Edd  +d+   +sd +   ++                +e D  
  gi|2396119   392 ELGVE-DEDDFIIDSDLVESDSEAELSL----------------DESDL- 423  

                   GAELEDkeGeeDdEeDedEES......DaEldvlkdLKedeaqplkgeai
                    A   D+e  e +EeD+ +  +   ++DaE d          +   ge +
  gi|2396119   424 -ASSADEE--ESEEEDDEFIGglvlppDAEADKRP-------ATTNGETP 463  

                   kasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDk
                    a+    A             +  ++Ft++cP +he +l+ ++    eD 
  gi|2396119   464 TAT----A-------------NNNLAFTYPCPENHEHFLQIVENTKIEDL 496  

                   plIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikkn
                   p++V+RI+ +hhp L+ +N K+kl  Fs vL qh    +  l++Q+   +
  gi|2396119   497 PTVVQRIRALHHPRLHIDN-KSKLATFSKVLVQHT--VY--LANQPDHPP 541  

                   LNfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhik
                     f  Le L  + +++a+  Pe+ a  +++ l+e+          +    
  gi|2396119   542 --FAVLENLLRHIHSMAKAQPEAVASAMRNHLREMSES------RP---- 579  

                   yPSl..kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkd
                    ++l ++dLv +  v+ +F+TSD  H+VvTP++l ma +L +s +  l  
  gi|2396119   580 -LELlpGDLVILTGVATIFPTSDHFHAVVTPSMLAMARYLGQSNIANLGN 628  

                   IaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitP
                   Ia G++++++  ++q   kRy+Pe ++ +   L   l p   V  l   P
  gi|2396119   629 IATGAYIATLCIQYQALAKRYIPEFMNYVVNVLC-ILAPSEPVHTLGFFP 677  

                   LtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpv
                      e     +l +   +  l ++k  t+  +   s+aD            
  gi|2396119   678 IRQEST---PLCLTPSKFPLTTIKKPTFWDILATSPAD--------GAEQ 716  

                   dalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrys..lke
                    al+ Sl +    ++L+  + + + + +AF  If P    L  ++++l  
  gi|2396119   717 EALKLSLIST--FISLLDQAADLWSSKSAFYDIFAPANRVLKYLTksLNN 764  

                   slpekRlkekll...davelveKltedakkerKPLAlqeHKPvaIrlleP
                   + p + l   l ++ d+++++ K  +     r PL l +H+P+aI +  P
  gi|2396119   765 KTPRT-LYDQLQrtcDKLQALLKQSD---LGRRPLLLHNHRPLAIKTAIP 810  

                   KFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakF
                   KFEE +    +P    yDpD+eR+elnKLka +KrE+KGA+RElRKDa F
  gi|2396119   811 KFEESF----NPSRH-YDPDRERAELNKLKAEHKRERKGAMRELRKDANF 855  

                   varlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +ar+ l Ek+ kd e+  K +++v+e+q +eg +   
  gi|2396119   856 IARESLREKREKDAEYERKYRRLVAEIQGEEGRE    889  

gi|147778528|emb|CAN71711.1|: domain 1 of 1, from 2 to 802: score 523.9, E = 1.9e-154
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        edr                   k +k      G+           
  gi|1477785     2    --EDRMLW----------------KETKD-----GK----------- 14   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                            s        
  gi|1477785    15 ----------------------------------------FS-------- 16   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                               ++ S  +a +l          ++ +       + s+  
  gi|1477785    17 ------------VK-SLYSALKLK---------TAVPF------MRSIIW 38   

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                   +          a ea                     ++  +KsKkEVmeE
  gi|1477785    39 SPYVPTKVGIFAWEA------------------SWDKK--HKSKKEVMEE 68   

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR.....
                   iI KSK+yKa +aK +ee e l ++LD+Nf +L+ ++a  +lt R+++ +
  gi|1477785    69 IISKSKFYKAQKAKDREENEHLVEELDKNFTSLVQSEALLSLT-Rpdkvn 117  

                   ................KsGiKkpreak....edtDaeYDlllkEMvfekR
                     +   +++ +++  +K  +   + +k+ ++e +D  YD+ + EM ++ R
  gi|1477785   118 alkalvnksipneymkKDDVSAMQHIKsfkqEQPDS-YDKIIGEMTLDMR 166  

                   AsPsdRTKTeEElAqkEaekLreLEeeRlkRMee.....teE.ledgEeE
                   A+PsdRTKT+EE+Aq+E+e+L+ LEeeR kRM +++++++eE+++ +++ 
  gi|1477785   167 ARPSDRTKTPEEIAQEERERLERLEEERQKRMLApndssDEEgDSREDA- 215  

                   iGGEESvkklkvrSvdDLdDsfsVEEDKP..KfGfiedlleREDNvdNeE
                      E S  +l+ +S+dDL+Dsfs  +  P++K G+  ++l+R D  + e 
  gi|1477785   216 --VEASNQRLRSISGDDLGDSFSL-DVLPesKKGWVYEVLDRKDTNELET 262  

                   ddEdddeeae....dsdDddsvndGtdlkqkKeavLkddEneDDd.LGAE
                   +d +  ee+e+++++sdD+  + d    +      Lkd+E++DDd+L  +
  gi|1477785   263 EDYGSSEESEspenESDDEGFEKD--NDNCEMTSSLKDWEQSDDDkLSTD 310  

                   L...EDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeai.kasvk
                   L+++ED+eGe + EeD+ EE    l  +++ K++  +     +i++   k
  gi|1477785   311 LegeEDEEGEQEGEEDDEEE-EKVLKIHQKAKDSGNAEINRNNIdSLDAK 359  

                   e.KANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIV
                   + K+N+K  ++      + sip+ i+ P++ eel  Ll+ ++  D   I+
  gi|1477785   360 KiKTNVKHPSSQ-----QDSIPYVIKAPTSLEELFMLLENCSDSDIVEII 404  

                   eRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfq
                    RI++ + + L+ eNRK+++v F+ vLLq+        ++++ kk+LNf 
  gi|1477785   405 HRIRINNAISLAVENRKKMQV-FYGVLLQYF-------AVLANKKPLNFK 446  

                   LLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl
                   LL+ Lv++L e++ e+P+++ai++++++l ++ +++e++k +E   +PSl
  gi|1477785   447 LLNLLVKPLMEISVEIPYFAAICARQRILRTRMQFCEAIKIPEKSSWPSL 496  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                   k+L++++L++ +F++SDfrH+V+TPa llm+e+L+r+p+ S+ dIaiG f
  gi|1477785   497 KTLFLLRLWSMIFPCSDFRHVVMTPATLLMCEYLMRCPILSGYDIAIGCF 546  

                   LvsiVLkfqsiSkRyvPeVvyalqqiL...............ftllvpKR
                   L+s VL  + +S+++ Pe + +lq  L    +++++ +++++f + ++  
  gi|1477785   547 LCSMVLSVVKQSRKFCPEAIMFLQTLLmvaldgnsklsqdsqF-YFFM-- 593  

                   DVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVt
                     el+ ++PL+ +r              +    ++ +l ++  +      
  gi|1477785   594 --ELKTLKPLLAIRG------------HVDDLSPLDFLTLMAMP-EG--- 625  

                   qtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLL
                      +  f++d +r+  L +  ++e++ ++v+iy++  +F+EIflPI++LL
  gi|1477785   626 ---SSFFSSDNFRACVLVS--IIETLQGFVDIYGGYNSFPEIFLPISTLL 670  

                   sryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIr
                    ++  +e +p   lkek+  +  l+  +t +++  r PL +++ KPv I 
  gi|1477785   671 LALAEQENMPNA-LKEKIRGVEVLIKEKTHEHHMLRQPLQMRKQKPVPIK 719  

                   llePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRK
                   l +PKFEEn+    + + + yDpD+eR+e  KLk+ +K E+KGA RElRK
  gi|1477785   720 LFNPKFEENF----VKGRD-YDPDRERAEQRKLKKLIKQEAKGAARELRK 764  

                   DakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   D +F   ++   ka ++ er+EK +k+ ++lqeqe+A+   
  gi|1477785   765 DNYFLFEVKKRDKAMQEEERAEKYGKARAFLQEQEHAF    802  

gi|240110482|gb|EER28640.1|: domain 1 of 1, from 40 to 881: score 523.2, E = 3.2e-154
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     ++ +++fNPF+ ++  r+ KF +    K      +
  gi|2401104    40    NRIHRNAV---LQELREQFNPFEARAPARpaKFAVTTN-KGNTDPVR 82   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV R+ +e++Rk Tl +e   +nK+g  +D+R+GE+++  +     E
  gi|2401104    83 HRPGVTRGLGEQRRKETLLKEIHSRNKTGMLLDRRFGENDPTMT----PE 128  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.....SvKD
                   e   eRf RE   Q+rL K ++ nl D ++   ++++ g+  + ++   D
  gi|2401104   129 ERAAERFARES--QRRLKKESMFNLEDDEDEEMLLTHGGQAlsfdkELGD 176  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFee....eDAeaeeeqrG
                   D+D++ + + e + +   ++    k++      e+  +++D+e + e++ 
  gi|2401104   177 DFDEGDLRDSEDDSESGRNNKR--KRLVEEDDMEGlagqSDDEEQPERK- 223  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                     KsK+EVm+EiIaKSK yK Er+K+Ke   Dl+  LD    ++  +++m
  gi|2401104   224 --KSKQEVMKEIIAKSKQYKYERQKAKEDDDDLRATLDQGLPSI--FEMM 269  

                   ekltsRKsGiKkpr.eakedt..............DaeYDlllkEMvfek
                      ++    + ++r+++  ++++    ++++++  D+eYD  lk M f+k
  gi|2401104   270 RGIKAPEPPLQEQRpDPMMNPdraallngkdrdaaDKEYDQRLKQMAFDK 319  

                   RAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEE
                   R +P+dRTKTeEE+A +Ea +Lr LE eRl+RM +  E+ +g +      
  gi|2401104   320 RSQPADRTKTEEEIAEEEATRLRQLEKERLRRMHG--EDDEGSA------ 361  

                   SvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEddde
                           ++ DLdD   V++ KP fG  + l  R D      d Ed+d+
  gi|2401104   362 ------DEGGADLDDDAEVDDAKP-FGLHQ-LTTRPDL-----DVEDEDD 398  

                   eaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEe
                    + + +    v  G  l          d   DD       D + e   Ee
  gi|2401104   399 FIIEDEL---VETGSAL----------DLSFDDS------DGS-ESAAEE 428  

                   DedEESDaEldvlkdLK.edeaqplkgeaikasvkeKANmKKsadTiPAS
                   D+d   D E  +   L++  e+ p  ++ ++                   
  gi|2401104   429 DDDDD-DDEFINGLTLRpGAESIPDDKKTLSTQ----------------- 460  

                   LdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNR
                    d s+++t++cP +hee+l  +k+   eD p++V+RI+ +hh  L+ +N 
  gi|2401104   461 -DGSLAYTYPCPESHEEFLNIIKDVKMEDLPTVVQRIRALHHSRLHSDN- 508  

                   KeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqel
                   K kl+KFs vL  h+   +  l+++    +  f  Le L  + ++la+  
  gi|2401104   509 KAKLGKFSRVLVEHV--SY--LANLREHPP--FAILENLLRHIHSLAKTH 552  

                   PeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTS
                   Pe  a  ++ +l+ v +        +     PS  dLv +  ++ +F+TS
  gi|2401104   553 PEDVAVAFRAQLRAVAND------RP-FNLLPS--DLVILTGISTIFPTS 593  

                   DfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyv
                   D  H+VvTPa+l m  +L +  ++Sl d  iG +  ++ L++q  SkRy+
  gi|2401104   594 DHFHPVVTPAMLSMGRYLGQGNIESLGDLVIGGYVTTLCLQYQALSKRYI 643  

                   PeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfa
                   Pe+v+ +  +L   l p          P    +       k   l  l+a
  gi|2401104   644 PELVNYVLNALC-ILAP--------TAP----KT------K---LGSLPA 671  

                   vkestllepqrLslaDLVtqtiteef............pvdalrsSlLli
                     +s   ep+rL  +D+     t+ f +  ++++  ++    l+ Sl   
  gi|2401104   672 RVPS---EPMRLEGTDVSAEVRTPSFwdiltgstvakdRAEGLKLSLVET 718  

                   KEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekRlkek
                       + +E++ e +   +AF E+f P  a L  + +s   + p   l+ +
  gi|2401104   719 --FTSILETAAELWATKSAFFEVFEPARAVLEHLikSCAGKVPTA-LSDH 765  

                   lldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPd
                   +  +        ++a++ r PL l +H+P+aI +  PKFEE +    +Pd
  gi|2401104   766 MQRTCHNMNAQLAEARRARRPLLLHNHRPLAIKTAIPKFEESF----NPD 811  

                   ksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakd
                      yDpD+eR+elnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+  d
  gi|2401104   812 RH-YDPDRERAELNKLKAEHKRERKGAMRELRKDANFIARESLREKRERD 860  

                   qerhEKmkkivnelqeqegAl<-*
                    e+  K +++ +e+q +eg +   
  gi|2401104   861 AEYERKYRRLIAEIQSEEGRE    881  

gi|119195743|ref|XP_001248475.1|: domain 1 of 1, from 40 to 880: score 521.2, E = 1.3e-153
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     ++ +++fNPF+ ++  r+ KF +    K      +
  gi|1191957    40    NRIHRNAV---LQELREQFNPFEARAPARpaKFAVTTN-KGNTDPVR 82   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV R+ +e++Rk Tl +e   +nK+g  +D+R+GE+++  +     E
  gi|1191957    83 HRPGVTRGLGEQRRKETLLKEIHSRNKTGMLLDRRFGENDPTMT----PE 128  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.....SvKD
                   e   eRf RE   Q+rL K ++ nl D ++   ++++ g+  + ++   D
  gi|1191957   129 ERAAERFARES--QRRLKKESMFNLEDDEDEEMLLTHGGQAlsfdkELGD 176  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFee....eDAeaeeeqrG
                   D+D++ + + e + +   ++    k++      e+  +++D+e + e++ 
  gi|1191957   177 DFDEGDLRDSEDDSESGRNNKR--KRLVEEDDMEGlagqSDDEEQPERK- 223  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                     KsK+EVm+EiIaKSK yK Er+K+Ke   Dl+  LD    ++  +++m
  gi|1191957   224 --KSKQEVMKEIIAKSKQYKYERQKAKEDDDDLRATLDQGLPSI--FEMM 269  

                   ekltsRKsGiKkpr.eakedt..............DaeYDlllkEMvfek
                      ++    + ++r+++  ++++    ++++++  D+eYD  lk M f+k
  gi|1191957   270 RGIKAPEPPLQEQRpDPMMNPdraallngkdrdaaDKEYDQRLKQMAFDK 319  

                   RAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEE
                   R +P+dRTKTeEE+A +Ea +Lr LE eRl+RM +  E+ +g +      
  gi|1191957   320 RSQPADRTKTEEEIAEEEATRLRQLEKERLRRMHG--EDDEGSA------ 361  

                   SvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEddde
                           ++ DLdD   V++ KP fG  + l  R D      d Ed+d+
  gi|1191957   362 ------DEGGADLDDDAEVDDAKP-FGLHQ-LTTRPDL-----DVEDEDD 398  

                   eaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEe
                    + + +    v  G  l          d   DD       D + e   Ee
  gi|1191957   399 FIIEDEL---VETGSAL----------DLSFDDS------DGS-ESAAEE 428  

                   DedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASL
                   D+d   D  +  l      e+ p  ++ ++                    
  gi|1191957   429 DDDDD-DEFINGLTLHPGAESIPDDKKTLSTQ------------------ 459  

                   drsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRK
                   d s+++t++cP +hee+l  lk+   eD p++V+RI+ +hh  L+ +N K
  gi|1191957   460 DDSLAYTYPCPESHEEFLNILKDVKMEDLPTVVQRIRALHHSRLHSDN-K 508  

                   eklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelP
                    kl+KFs vL  h+   +  l+++    +  f  Le L  + ++la+  P
  gi|1191957   509 AKLGKFSRVLVEHV--SY--LANLREHPP--FAILENLLRHIHSLAKTHP 552  

                   eklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSD
                   e  a  ++ +l+ v +        +     PS  dLv +  ++ +F+TSD
  gi|1191957   553 EDVAVAFRAQLRAVAND------RP-FNLLPS--DLVILTGISTIFPTSD 593  

                   frHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvP
                     H+VvTPa+l m  +L +  ++Sl d  iG++  ++ L++q  SkRy+P
  gi|1191957   594 HFHPVVTPAMLSMGRYLGQGNIESLGDLVIGAYVTTLCLQYQALSKRYIP 643  

                   eVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfav
                   e+v+ +  +L   l p          P    + +L+s+   +P +     
  gi|1191957   644 ELVNYVLNALC-ILAP--------TAP----KTKLGSFPARVPSEPMRLE 680  

                   kestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeivei
                         e+ + s  D+ t           l+ Sl       + +E++ e 
  gi|1191957   681 GTDVSAEVRTPSFWDVLTGSTVAKDRAEGLKLSLVET--FTSILETAAEL 728  

                   yyklqAFiEIflPIlaLLsry..slkeslpekRlkeklldavelveKlte
                   +   +AF E+f P  a L  + +s   + p   l+ ++  +        +
  gi|1191957   729 WATKSAFFEVFEPARAVLKHLirSCAGKVPTA-LSDHMQRTCHSMNAQLA 777  

                   dakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRsel
                   +a++ r PL l +H+P+aI +  PKFEE +    +Pd   yDpD+eR+el
  gi|1191957   778 EARRARRPLLLHNHRPLAIKTAIPKFEESF----NPDRH-YDPDRERAEL 822  

                   nKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivne
                   nKLka +KrE+KGA+RElRKDa F+ar+ l Ek+  d e+  K +++ +e
  gi|1191957   823 NKLKAEHKRERKGAMRELRKDANFIARESLREKRERDAEYERKYRRLIAE 872  

                   lqeqegAl<-*
                   +q +eg +   
  gi|1191957   873 IQSEEGRE    880  

gi|154285976|ref|XP_001543783.1|: domain 1 of 1, from 37 to 889: score 519.9, E = 3.2e-153
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r     A + i+++fNPF++k+  r+ KF    r        +
  gi|1542859    37    GAASRIHRNAALQGIREQFNPFEIKAPTRpaKFSSVSR--SNQDAPR 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e + + K g  +D+R+GE+++  +     E
  gi|1542859    82 SRPGVTKGLGEQRRKETLLKEMQRRSKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e   eRf RE   Q+rL K ++ nl D +E v  ++++g++     +   
  gi|1542859   128 ERAAERFARES--QRRLKKESMFNLEDDEEEV-QLTHLGQT-----ITFD 169  

                   eelgeeLsdddELadeaLDk.........dfla....lkrFeeeDAeaee
                      +++ ++dd+  +++  +++ ++ ++++++a+++++ +  e+  e  +
  gi|1542859   170 ADNRDDFQEDDLNVSDE--EgnvekirkrRRTAeeddMEGLAEDSEEEGQ 217  

                   eqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLls
                   + r  kKsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+    +  
  gi|1542859   218 PER--KKSKNEVMKELIAKSKFHKYERQKAKEDDDDLRASLDKGLPEI-- 263  

                   llamekltsRKsGiKkpreakedt......................DaeY
                   +++m  ++      K + e+ + ++   + ++++    +++++++ D+eY
  gi|1542859   264 FEMMRGVK------KPEPEPLPQPdlaatmnpdraallngkprdeaDKEY 307  

                   DlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEl
                   D  lk M  +kRA P dRTKTeEE+A +Eae+Lr LE eRl+RM++ + +
  gi|1542859   308 DQRLKQMTYDKRANPVDRTKTEEEKAEEEAERLRQLEKERLRRMQGAGDD 357  

                   edgEeEiGGEESv.................kklkvrSvdDLdDsfsVEED
                     +E +  GEE v++++++++ +  +  ++k+ +   v+D+dD       
  gi|1542859   358 LSEEQDSNGEEEVednsepddakafglaqpKRIQEFAVEDEDD------- 400  

                   KPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKe
                        fi          d  E+d     +  +sd   s +          
  gi|1542859   401 -----FII-------DRDLVESDSEAELLLDESDM-ASAST--------- 428  

                   avLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaq
                                     D+e    + eD+++                  
  gi|1542859   429 ------------------DEE---SEAEDDGFI----------------G 441  

                   plk.......geaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                    l+ +++ +  ++++ +          ++T  A  + +++Ft++cP++he
  gi|1542859   442 GLVlppgakaDKGPSTT-------NGESST--ALTNNDLAFTYPCPRSHE 482  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                    +l+ +k+  +eD p++V+RI+ +hhp L+++N K+kl  Fs vL qh  
  gi|1542859   483 HFLQIIKDTKTEDLPTVVQRIRALHHPGLHGDN-KSKLATFSQVLVQHT- 530  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                     +  l++Q+   +  f  Le L  + +++a+  Pe+ a  ++  l+e+ 
  gi|1542859   531 -VY--LANQPNHPP--FAVLENLLRHVHSMAKAQPEAVASAMRDHLREMS 575  

                   kelaeeykknEhikyPSl..kdLvfFkLvgllFsTSDfrHlVvTPalllm
                            +     ++l ++dLv +  v+ +F+TSD  H+VvTP++l m
  gi|1542859   576 ET------RP-----LELlpGDLVILTGVATIFPTSDHFHAVVTPSILAM 614  

                   aevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftl
                   a +L +s +  l  Ia G++++++  ++q   kRy+Pe ++ +   L   
  gi|1542859   615 ARYLGQSNITNLGNIATGAYIATLCIQYQTLAKRYIPEFMNYVLNGLC-I 663  

                   lvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl
                   l p    e l + PL        +l +        +  e+ l  + +L  
  gi|1542859   664 LAPIEPKETLGLFPLRQPSV---PLHL--------TASELPLTHIRKLTF 702  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                    D+  +  t       l+ Sl +    + L+  + + + + +AF  If P
  gi|1542859   703 WDVLAKSSTDSREQESLKLSLIST--FITLLDHAADLWSSKSAFHDIFAP 750  

                   IlaLLsry..slkeslpekRlk...eklldavelveKltedakkerKPLA
                       L  +++sl  + p++ l+++ +++ld+++ + K  +     r PL 
  gi|1542859   751 ANRVLKHLnhSLNNKSPST-LSdqlQRILDKLQVLLKQSD---LARRPLL 796  

                   lqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrE
                   l +H+P+aI +  PKFEE +    +P    yDpD+eR+elnKLka +KrE
  gi|1542859   797 LHNHRPLAIKTAIPKFEESF----NPSRH-YDPDRERAELNKLKAEHKRE 841  

                   kKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-
                   +KGA+RElRKDa F+ar+ l Ek+ kd e+  K +++v+e+q +eg +  
  gi|1542859   842 RKGAMRELRKDANFIARESLREKREKDAEYERKYRRLVAEIQGEEGRE   889  

                   *
                    
  gi|1542859     -   -    

gi|281340003|gb|EFB15587.1|: domain 1 of 1, from 1 to 817: score 519.1, E = 5.8e-153
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                         +r              NPF+vkv++ KF +lGr   k ++++G 
  gi|2813400     1    ---ARPNP-----------NPFEVKVNRQKFPVLGR---KARHAVGQ 30   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a++kR +Tl +e+k + Ks++f DkR+GE     s     EeK
  gi|2813400    31 PGVSRARAVQKRTQTLLKEYKERDKSNVFTDKRFGEYSSNMS----PEEK 76   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q++  Kr+ ynln+G    ee+++ g s    D++    
  gi|2813400    77 MIKRFALEQ--QRQHEKRSIYNLNEG----EELTHYGRS--LADIEKHDD 118  

                   lgeeLsdddELadeaLDkdflalkrFee............eDAeaeeeqr
                     ++ sd +E    +  + ++a+ +F+++++  +++++++ + e+e+++ 
  gi|2813400   119 IVDSDSDTEERGTLS--AELTAA-HFGGgggllhkktpqqQGEEGEKPRS 165  

                   GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlslla
                         +E +eE IaKSK  K Er++++e    l++kLD   k ++ ll 
  gi|2813400   166 -----RRELIEELIAKSKQEKRERQAQREGALELTEKLDQDWKEIQTLLT 210  

                   mekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEEl
                      ++   s   +  e k+ +Da YD  ++E+ fe  A+Ps R KT EEl
  gi|2813400   211 HRAPK---SENRDKTE-KPKPDA-YDVMVRELGFEMKAQPSNRIKTVEEL 255  

                   AqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLd
                   A++E e+L +LE eRl+RM++  E   g++        +k+k+ S+dDL 
  gi|2813400   256 AKEEQERLQKLEAERLRRMRGEDE--GGDA--------RKPKHLSADDLN 295  

                   DsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndG
                   D           Gf +              d dd  +    d+    +  
  gi|2813400   296 D-----------GFVL--------------DRDDRRLLSYTDG--KMSI- 317  

                   tdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeD..edEESDaEldv
                               + E++         D e ee+++eD +ed E  +  d 
  gi|2813400   318 ------------GEEQSGEA-----SDGESEEEQGEDlsEDPEDSSDPDG 350  

                   lkdLKedeaqplkgeaikasvkeKANmKKsadTiPA..SLdrsipFtidc
                   ++dL e+  +++    +  +    A  K++ +   A+++  + +p+t+  
  gi|2813400   351 HSDL-ESDTESEDCGRPDRE-PQQAPGKRMTSGHRArgATRTELPYTFAA 398  

                   PktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvL
                   P ++eel  Ll+    e    +VeRI +++hp L+ +N K kl+K+  +L
  gi|2813400   399 PESYEELKSLLSAKTMEEQLAVVERIQTCNHPSLAVGN-KAKLEKLFGFL 447  

                   LqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislsee
                   L ++     Dl+  d      +    kLv  L+ l q +P  +  s   +
  gi|2813400   448 LEYV----GDLATDDPPD---LRVIDKLVVQLYNLCQMFPDSASNSIKFV 490  

                   llevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPal
                   l++   e+  ++       +P l+ Lv++k+ gllF+ SD rH+VvTPal
  gi|2813400   491 LRDAMHEMEGSIEARGRAAFPGLDVLVYLKIAGLLFPASDLRHPVVTPAL 540  

                   llmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiL
                     m++ L +++v Sl+d+ +Glf + ++L ++s S+R++Pe++++l +iL
  gi|2813400   541 VCMSQLLTKCRVLSLQDVVKGLFVCCVFLDYVSLSRRFIPELINFLLGIL 590  

                   ftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqr
                   + l  p +      ++  +F     +  ++   l+ +    ++       
  gi|2813400   591 Y-LAAPNKHGQGYTLVH-PFRAS--GKNSE---LLLVSDEADIATWQRRG 633  

                   Lsla...DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAF
                   Lsl   + L  qt te+  +++   S L +   l Lv   v  y++l++F
  gi|2813400   634 LSLRwagGLKAQTKTEANHTRL---SCLAV--CLALVKRCVLLYGSLPSF 678  

                   iEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPL
                     I  P  aLL         p   l+e   +++   eK  e   +   PL
  gi|2813400   679 HDIVRPLGALLTEHLADHRHPLE-LQELCRSTLADMEKQ-E---QRCRPL 723  

                   AlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKr
                      + KPv + l  P+   + +  R  + s     ke  e+  L +k+Kr
  gi|2813400   724 ICEKSKPVPLKLFTPRLVRVLEFGRKQGSS-----KEEQERRRLIHKHKR 768  

                   EkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<
                   E KGA+RE+R+D +F ar  l E++  d er  K+k + n l +qeg+  
  gi|2813400   769 EFKGAVREIRRDNQFLARMQLSETLERDAERKRKVKQLFNSLATQEGEW  817  

                   -*
                     
  gi|2813400     -    -    

gi|240277261|gb|EER40770.1|: domain 1 of 1, from 37 to 889: score 516.8, E = 2.8e-152
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r     A + i+++fNPF++k+  r+ KF    r        +
  gi|2402772    37    GAASRIHRNAALQGIREQFNPFEIKAPTRpaKFNSVSR--SNQDAPR 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e + + K g  +D+R+GE+++  +     E
  gi|2402772    82 SRPGVTKGLGEQRRKETLLKEMQRRSKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e   eRf RE   Q+rL K ++ nl D +E v  ++++g++     +   
  gi|2402772   128 ERAAERFARES--QRRLKKESMFNLEDDEEEV-QLTHLGQT-----ITFD 169  

                   eelgeeLsdddELadea...LDkdflalkrFeeeD......AeaeeeqrG
                    e++++ ++dd+  ++++++L+k ++     ee+D ++  +++ ee q  
  gi|2402772   170 AESRDDFQEDDLNVSDEegnLEKIRKRRRTAEEDDmeglaeDSEEEGQPE 219  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                    kKsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+    +  +++m
  gi|2402772   220 RKKSKNEVMKELIAKSKFHKYERQKAKEDDADLRASLDKGLAEI--FEMM 267  

                   ekltsRKsGiKkpreakedt......................DaeYDlll
                     ++      K + e+ + ++   + ++++    +++++++ D+eYD  l
  gi|2402772   268 RGVK------KPEPEPLPQPdlvatmnpdraallngkprdeaDKEYDQRL 311  

                   kEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgE
                   k M  +kRA P dRTKTeEE+A +Eae+Lr LE eRl+RM++ + +  +E
  gi|2402772   312 KQMTYDKRANPVDRTKTEEEKAEEEAERLRQLEKERLRRMQGAGDDLSEE 361  

                   eEiGGEESvkklkvrSvdDLdDsfsVEEDKPK.fGfiedlleREDNvdNe
                                  + +D  D  + E D  K fG  +     E  v+  
  gi|2402772   362 Q-----------DSNGEEDVED--NSEPDDAKaFGLAQPKSIQEFAVE-D 397  

                   EddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDk
                   Edd  +d    +sd               ea L  dE +           
  gi|2402772   398 EDDFIIDRDLVESDS--------------EAELFLDESDMAS------AS 427  

                   eGeeDdEeDedEESDaEldvlkdLKedeaqp...lkgeaikasvkeKANm
                    Gee + eD+ +                  p++ ++ ++++ +       
  gi|2402772   428 TGEESEAEDDEFI------------GGLVLPpgvEVDKGPSTT------- 458  

                   KKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIika
                      ++T     +  ++Ft++cP++h  +l+ +k+  +eD p++V+RI+ +
  gi|2402772   459 NGESST--VLTNNNLAFTYPCPRSHGHFLQIIKDTKTEDLPTVVQRIRAL 506  

                   hhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLv
                   hhp L+ +N K+kl  Fs vL qh    +  l++Q+   +  f  Le L 
  gi|2402772   507 HHPRLHSDN-KSKLATFSQVLVQHT--VY--LANQPNHPP--FAVLENLL 549  

                   eaLielaqelPeklaislseellevikelaeeykknEhikyPSl..kdLv
                    + +++a+  Pe+ a  ++  l+e+          +     ++l ++dLv
  gi|2402772   550 RHVHSMAKAQPEAVASAMRDHLREMSET------RP-----LELlpGDLV 588  

                   fFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsi
                    +  v+ +F+TSD  H+VvTP++l ma +L +s +  l  Ia G++++++
  gi|2402772   589 ILTGVATIFPTSDHFHAVVTPSILAMARYLGQSNITNLGNIATGAYIATL 638  

                   VLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDs
                     ++q   kRy+Pe ++ +   L   l p    e l + PL        +
  gi|2402772   639 CIQYQTLAKRYIPEFMNYVLNGLC-ILAPIEPKETLGLFPLRQPSV---P 684  

                   lekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLli
                   l +        +  e+ l    +L   D+     t      al+ Sl + 
  gi|2402772   685 LHL--------TASELPLTHTRKLTFWDVLANSSTDSREQEALKLSLIST 726  

                   KEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekRlk..
                      + L+  + + + + +AF  If P    L  +++sl  + p++ l+++
  gi|2402772   727 --FITLLDHAADLWSSKSAFHDIFAPANRVLKHLnhSLNIKSPST-LSdq 773  

                   .eklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKR
                    +++l++++ + K  +     r PL l +H+P+aI +  PKFEE +    
  gi|2402772   774 mQRILNKLQVLLKQSD---LARRPLLLHNHRPLAIKTAIPKFEESF---- 816  

                   sPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEka
                   +P    yDpD+eR+elnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+
  gi|2402772   817 NPSRH-YDPDRERAELNKLKAEHKRERKGAMRELRKDANFIARESLREKR 865  

                   akdqerhEKmkkivnelqeqegAl<-*
                    kd e+  K +++v+e+q +eg +   
  gi|2402772   866 EKDAEYERKYRRLVAEIQGEEGRE    889  

gi|157138692|ref|XP_001657340.1|: domain 1 of 1, from 10 to 835: score 515.0, E = 9.4e-152
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       +++   K K  + ++k  NPF+++ +k KF il r     +   G 
  gi|1571386    10    DSDALLKK-KSLQGVKKP-NPFEIQTSKAKFTILNRDSQPNRRFAGI 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRi.GErnkhLsGDqLeEe
                   PGV Ra+a+ekRk+Tl++ef  knKs++f D R +G      s       
  gi|1571386    55 PGVQRARAIEKRKQTLGQEFLLKNKSNRFTDQRKdG---RNMS----RDQ 97   

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsle
                      eR s+     +r   +e+ynln    D   +++rg++     l+++e
  gi|1571386    98 MATERKSAAT---RR---KELYNLN----DTVKLTHRGQT-----LEEIE 132  

                   elgeeLsdddELade..aLDkdflalkrFeeeDAeaeeeqrGAkKsKkEV
                     ++  + dd  +d+++ L++df+ +++F++    +e+++r  +K+   V
  gi|1571386   133 RFDDAVDNDDDSDDDggQLEADFMEAAHFGGGEEDGEDRGR-DRKT---V 178  

                   meEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKs
                   +eE+Ia+SK++KaE++ e +ev+  + kLD N  +L+s + +  +     
  gi|1571386   179 IEEMIAESKRRKAEKQRENDEVYEMTQKLDQNWQSLMSVVGDHMKG---- 224  

                   GiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLr
                            + +D+ YD+  +EM+fe R++P+d++K eEElA +E+ kL+
  gi|1571386   225 -----DSVRPQLDD-YDKIMREMIFERRGAPADKLKSEEELANIEKQKLE 268  

                   eLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDK
                   +LE eRl RM+++      E+         k  +rS+dDLdD        
  gi|1571386   269 KLERERLARMKGDDV----EA---------KGNHRSADDLDD-------- 297  

                   PKfGfiedlleREDNvdNeE.ddEdddeeaed.........sdDddsvnd
                      G+ +   +      NeE +++  d  aed+  ++++ ++++      
  gi|1571386   298 ---GYLLQPID-----GNEEaSYNEADVDAEDglynprqisEEG------ 333  

                   GtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvl
                          Ke       ++DD+      D e   +dE  edE+    +d+l
  gi|1571386   334 -------KEDKADVEDESDDE------DSEAGSEDEVSEDES-EDGVDNL 369  

                   kdLKed.eaqplkg...............eaikasvkeKANmKKsadTiP
                   +dLKed+e++ ++  ++ +++++++++++ a k    eKA          
  gi|1571386   370 SDLKEDsESEEEVAatemnkqskqpdpetQAAKQA-REKA---------- 408  

                   ASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkee
                      +  +pFt++ P+ +e l eLl   + +    I  R  k +  K   e
  gi|1571386   409 ---EAELPFTFELPRKYEQLEELLQRRSSAEQLVILDRMVKSNNAKFSRE 455  

                   NRKeklvKFsvvLLqhIKDLfEDlse.QdikknLNfqLLekLveaLiela
                   N K k+v ++++LLqh+ DLf  +++++ ++   Nf LL  L + L+ la
  gi|1571386   456 N-KQKMVSLYAFLLQHLNDLF--AAVgLESLHD-NFRLLDGLSPFLYDLA 501  

                   qelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllF
                   + +P       s+  l+vike++eey+k     yP l+ L+f+kLv  lF
  gi|1571386   502 KINPTE----TSQCFLDVIKEKQEEYRKK-PRLYPHLDSLIFLKLVPVLF 546  

                   sTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSk
                   s SDfrH+VvTPal ++++ Lsr+ v+ +kd+  GlfLv  VL+ + +Sk
  gi|1571386   547 SASDFRHPVVTPALVFISQLLSRCQVRNRKDVTSGLFLVMTVLECVEQSK 596  

                   RyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldn
                   R++P+ +++l + L+ l + KR +    ++P +F            Pl n
  gi|1571386   597 RFLPAAINFLNGVLY-LCFRKRSITVVPVVP-PFKSS--------APLNN 636  

                   lfavkestllepqrLslaDLVtqtiteefpvdalrsSl....LliKEvle
                   l a  est+    ++           e+f   + + S + ++L+   +le
  gi|1571386   637 LLALDESTKNCDEKEYALH------CEDFFIEDVDDSFklrtLSA--ALE 678  

                   LvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavel
                    ++         +A     + +   L r+   e lp   lk  l  ++  
  gi|1571386   679 MIARSFRQLRDTSAVHQLSIEVIRSLERLDE-ELLPAV-LKVSLNETLNT 726  

                   veKltedakkerKPLAlq...eHKPvaIrllePKFEEnyDD.KRsPdksS
                   v  l         PL     +e KP+ +rllePK E++yDD +R+P+   
  gi|1571386   727 VKALHL------RPLLFLlapEQKPKPLRLLEPKIEAVYDDiRRRPKNQ- 769  

                   yDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqer
                         R  + KL  k K+E + A RE+R D  F+a l  k++aa+d er
  gi|1571386   770 --QLSDRDKRRKLQQKVKKESRAAAREIRQDNEFIAKLQFKQRAASDRER 817  

                   hEKmkkivnelqeqegAl<-*
                    EK+k+i   + +q+g+l   
  gi|1571386   818 REKVKRIFSDATTQQGEL    835  

gi|213513131|ref|NP_001133389.1|: domain 1 of 1, from 9 to 846: score 514.5, E = 1.4e-151
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +  d+  K K   +i+   NPF+vk +++KFdilGr   k K+++G 
  gi|2135131     9    NLADKVRKTKTSTEIKN--NPFEVKINRKKFDILGR---KSKHDVGL 50   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka+ kRk Tl +e+k k K + fiD+R+GE +         EeK
  gi|2135131    51 PGVSRSKAINKRKETLLKEYKTKDKANKFIDRRFGEYDTKMD----PEEK 96   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    l Rfs Er  Q+   K+++ynln  +E  ee+++ g+s     l ++e+
  gi|2135131    97 ILQRFSMER--QRTQDKKNMYNLN--EE--EELTHYGQS-----LSEMEK 135  

                   lgeeLsdddELadeaLDkdflalkrFeeeD..........AeaeeeqrGA
                   l +  + dd  +   +    l + +F++ +  +++++++++ +   ++  
  gi|2135131   136 LNDMVDSDDDADEKGMLSAELTASHFGGGGllrrktqgekDNGGNQRA-- 183  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                    Ks +E +eE I KSK  K Er+ +Kee   l++kLD   k+++ lla  
  gi|2135131   184 -KSRQELIEELILKSKQEKRERQNQKEESQVLTEKLDQDWKSIQGLLA-H 231  

                   kltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAq
                   k +        + e k+ +D  YD  ++E+ fe  A+Ps++ KT+EE A 
  gi|2135131   232 KNA--PKADRHEEEDKPKLDE-YDMMVRELGFEMKAQPSEKMKTPEEVAR 278  

                   kEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDs
                   +E+e+L +LE  Rl+RM ++     g+        +k   + S+dD  D 
  gi|2135131   279 EERERLQKLEADRLRRMMGDAV---GDC-------TKTQAHMSADDINDG 318  

                   fsVE.EDKPKfGfiedlleREDNvdNeE..ddEdddeeaedsdDddsvnd
                   f  +++DKP   + ++         NeE+   E+ddee  + +  + ++d
  gi|2135131   319 FILDgDDKPTLAYQDGKWN-----INEEgaKIEGDDEEGGEGESGEEESD 363  

                   GtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvl
                           e     dE++  dL  E E   Gee++Ee e  E        
  gi|2135131   364 --------EEEEGSDEDSHSDLDSEQESAGGEEEEEEEEKDE-------- 397  

                   kdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkt
                           +p  ++ ++ +   KA     a+         +p+t++ P +
  gi|2135131   398 --------APATKSQLSEE-ERKA----QAEA----AKAELPYTFKAPES 430  

                   heelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqh
                   + +l  Ll ++  +   +I  R  k++hp L+ +N K kl K+  +LL +
  gi|2135131   431 YSDLKGLLQGHPADHQCIILARTQKCNHPSLAVGN-KLKLQKLFGFLLEY 479  

                   IKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseelle
                   +        e++++++  +    k  + L+ l q++Pe++   +  +l +
  gi|2135131   480 V-------GELASRSPPELSTIDKMIPQLYGLCQLFPEAASKAMQTTLVD 522  

                   vikelaeey.kknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalll
                       + e  ++k     +P l+ L+++k+++llF+TSDfrH+V TPall 
  gi|2135131   523 SAHSMEEVLeVKG-RAAFPQLDMLIYLKITALLFPTSDFRHPVTTPALLY 571  

                   maevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLft
                   +++ L ++pv Sl d+  Gl+L+ +  ++ s SkR+ Pe++++l + L+ 
  gi|2135131   572 ISQALTKCPVMSLEDVTSGLVLCCLAVEYISFSKRFFPELINFLLGVLH- 620  

                   llvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLs
                   l v  +     s++P +F +   +  +    l++l     s      +L+
  gi|2135131   621 LAVKDKTSTGYSVVP-PFRQK--GKVSD---LLVLSDPESSQTWSKKTLP 664  

                   laDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIfl
                   l    t t+t ++ +d  r S       l L+   +  y  l ++  If 
  gi|2135131   665 LSATQTLTLTTDLDTDHYRLSAVAT--CLDLLKRCSSLYRELASYSHIFK 712  

                   PIlaLLsr.yslkeslpekRlkeklldavelveKltedakkerKP.LAlq
                   PI +LLs++++  + +p   l+  +   + +++ +         P L   
  gi|2135131   713 PITTLLSKhLPI-KTYPAA-LQDLHGEILAAISGSLM-----SRPlLVFE 755  

                   eHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnK..LkaklKrE
                   ++KP+ + l  PK  E+       +k+      +++e+ K++L +k K+E
  gi|2135131   756 KKKPIPLKLFTPKIVEVL----DYGKK---RGNTKEEREKerLNHKYKKE 798  

                   kKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-
                    KGA RE+RKD++F ar++l E    d er  K+k +   l +qeg+   
  gi|2135131   799 FKGALREIRKDTRFLAREKLNEVMGRDAERKRKVKELFGSLATQEGEW   846  

                   *
                    
  gi|2135131     -   -    

gi|238508485|ref|XP_002385435.1|: domain 1 of 1, from 37 to 898: score 512.7, E = 4.8e-151
                   *->keedreeKKKAvakiqkefNPFdvkv..akrKFdilGr...sKtkvK
                          r     A + i+ +fNPF++k+++++ KFd+  r+++s t+  
  gi|2385084    37    AAQNRVQRNAALQSIRDRFNPFEIKAggTRTKFDVTTRdgnSGTAAS 83   

                   geeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                    ++  PGV +  +eekR++Tl  e +k+nK g+++D+R+GE ++  +   
  gi|2385084    84 RAR--PGVTKSLGEEKRRQTLLREMEKRNKVGGILDRRFGEDDPTMT--- 128  

                   LeEeKMleRfsRErmSQlrLSKreaynln.DGlEDveedGdrggsSvKDD
                     Ee   eR+ R    Q+++ K ++ nl +D +E    +++ g+s     
  gi|2385084   129 -PEERAAERYARAS--QRKMRKESMFNLEgDDEEEEFQLTHKGQS----- 170  

                   lDsleelge.eLsdddELadeaLD..kdflalkrFeeeD.........Ae
                   l  + + +++e +++ +++d++ D+++ ++    F ++++ +++++ ++ 
  gi|2385084   171 LNDIDQDDFqEGDLGGLEDDAS-DteAARKRKRVFFDDGemdgpedleDG 219  

                   aeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkd
                    e + r  kKsK EVm+E+IaKSKl K Er+K+Ke   Dl+++LD+   d
  gi|2385084   220 EEHPER--KKSKHEVMKEVIAKSKLHKYERQKAKEDDDDLREELDKGLPD 267  

                   LlsllamekltsRKsGiKkpreake...................dtDaeY
                   L   l   k+        kp ++k++  + ++++    ++  ++dt +eY
  gi|2385084   268 LFEMLRGVKPP------PKPEPPKSdlasmnpdraalmegiakgDTEKEY 311  

                   DlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeete..
                   D  lk + f+kR +P+dRTKTeEE+A++Eae+L +LEeeR +RM++ e +
  gi|2385084   312 DQRLKQLTFDKRSKPTDRTKTEEEKAAEEAERLKALEEERVRRMRGEEvg 361  

                   ..EledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleR
                   ++E ed+EeE+  E S         dD  + f     +   G i      
  gi|2385084   362 esEEEDEEEEVEEEGSEMSEDESIPDDAKA-FGL---QQSSGQIS--TRP 405  

                   EDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdL
                   E  v+ e d+  dd++ e   D   v++                ++D + 
  gi|2385084   406 ELSVEDEDDFIIDDDLVETRSD---VSL-------------SIGDSDEE- 438  

                   GAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqpl..kgeaikasv
                      L  +e ee+ EeDe  E          L +    p ++ gea+ a  
  gi|2385084   439 --VLSAEESEEEMEEDEEDE----------LINGFTLPTdnTGEAPAAAD 476  

                   keKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIV
                      A             +  +++t++cPk+hee+l+ + +   +D p +V
  gi|2385084   477 APEA-------------NEGLAYTYPCPKNHEEFLQVIQDVPMADLPVVV 513  

                   eRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfq
                   +RI+ +hh  L+++N K+kl+ Fs +L qh+   +  ++eQ+   +  f 
  gi|2385084   514 QRIRALHHHRLHPDN-KKKLGQFSRILIQHV--AY--MAEQPEHPP--FA 556  

                   LLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl
                    Le    + ++la++ Pe    +++ +l+e+      + + +        
  gi|2385084   557 ILENIFRHVHSLAKSHPESVSQEFRARLREIAADRPLSLR-P-------- 597  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                   +dLv +  ++  F+TSD  H+V TPa l ++ +L +  v++l d a G++
  gi|2385084   598 SDLVILTGIATTFPTSDHFHAVATPAHLCLSRYLGQGAVNTLADFATGAY 647  

                   LvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerd
                    +s+VL++q  SkRy Pe+++ +  +L   l p    e+     ++F   
  gi|2385084   648 AASLVLQYQLVSKRYMPELINYVLNALC-NLAP----EEPKSSLGLFPSR 692  

                   RLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsS
                      s e+          k s  l+  +L+  D +t   ++      l+ S
  gi|2385084   693 ---SPEE------SLRLKISKSLKSRKLQFWD-ITGPDSPK-AQEELKLS 731  

                   lLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekR
                   l +    ++L+ ++++ +   +AF EIf   +  L  +++s k ++p+  
  gi|2385084   732 LINT--FISLLSTASDMWSDISAFLEIFDQAQKVLRFLnrSCKGKIPSV- 778  

                   lkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDK
                   ++  l +++ ++   t  a+  r PL l  H+P+aI +  PKFE  +   
  gi|2385084   779 VQDTLQSTLDKLDGHTSKARLTRRPLLLHDHRPLAIKTAIPKFEDTF--- 825  

                   RsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEk
                    +Pdk  yDp +eR+e n Lka  KrE+KGA+RElRKDa F+ar++l Ek
  gi|2385084   826 -NPDKH-YDPNRERAEANRLKAEYKRERKGAMRELRKDANFIAREKLREK 873  

                   aakdqerhEKmkkivnelqeqegAl<-*
                      d e+  K k++v+e+q qeg +   
  gi|2385084   874 KERDAEYEKKYKRLVAEVQNQEGRE    898  

gi|169784386|ref|XP_001826654.1|: domain 1 of 1, from 37 to 898: score 507.3, E = 1.9e-149
                   *->keedreeKKKAvakiqkefNPFdvkv..akrKFdilGr...sKtkvK
                          r     A + i+ +fNPF++k+++++ KFd+  r+++s t+  
  gi|1697843    37    AAQNRVQRNAALQSIRDRFNPFEIKAggTRTKFDVTTRdgnSGTAAS 83   

                   geeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                    ++  PGV +  +eekR++Tl  e +k+nK g+++D+R+GE ++  +   
  gi|1697843    84 RAR--PGVTKSLGEEKRRQTLLREMEKRNKVGGILDRRFGEDDPTMT--- 128  

                   LeEeKMleRfsRErmSQlrLSKreaynln.DGlEDveedGdrggsSvKDD
                     Ee   eR+ R    Q+++ K ++ nl +D +E    +++ g+s     
  gi|1697843   129 -PEERAAERYARAS--QRKMRKESMFNLEgDDEEEEFQLTHKGQS----- 170  

                   lDsleelge.eLsdddELadeaLD..kdflalkrFeeeD.........Ae
                   l  + + +++e +++ +++d++ D+++ ++    F ++++ +++++ ++ 
  gi|1697843   171 LNDIDQDDFqEGDLGGLEDDAS-DteAARKRKRVFFDDGemdgpedleDG 219  

                   aeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkd
                    e + r  kKsK EVm+E+IaKSKl K Er+K+Ke   Dl+++LD+   d
  gi|1697843   220 EEHPER--KKSKHEVMKEVIAKSKLHKYERQKAKEDDDDLREELDKGLPD 267  

                   LlsllamekltsRKsGiKkpreake...................dtDaeY
                   L   l   k+        kp ++k++  + ++++    ++  ++dt +eY
  gi|1697843   268 LFEMLRGVKPP------PKPEPPKSdlasmnpdraalmegiakgDTEKEY 311  

                   DlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeete..
                   D  lk + f+kR +P+dRTKTeEE+A++Eae+L +LEeeR +RM++ e +
  gi|1697843   312 DQRLKQLTFDKRSKPTDRTKTEEEKAAEEAERLKALEEERVRRMRGEEvg 361  

                   ..EledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleR
                   ++E ed+EeE+  E S         dD  + f     +   G i      
  gi|1697843   362 esEEEDEEEEVEEEGSEMSEDESIPDDAKA-FGL---QQSSGQIS--TRP 405  

                   EDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdL
                   E  v+ e d+  dd++ e   D   v++                ++D + 
  gi|1697843   406 ELSVEDEDDFIIDDDLVETRSD---VSL-------------SIGDSDEE- 438  

                   GAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqpl..kgeaikasv
                      L  +e ee+ EeDe  E          L +    p ++ gea+ a  
  gi|1697843   439 --VLSAEESEEEMEEDEEDE----------LINGFTLPTdnTGEAPAAAD 476  

                   keKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIV
                      A             +  +++t++cPk+hee+l+ + +   +D p +V
  gi|1697843   477 APEA-------------NEGLAYTYPCPKNHEEFLQVIQDVPMADLPVVV 513  

                   eRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfq
                   +RI+ +hh  L+++N K+kl+ Fs +L qh+   +  ++eQ+   +  f 
  gi|1697843   514 QRIRALHHHRLHPDN-KKKLGQFSRILIQHV--AY--MAEQPEHPP--FA 556  

                   LLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl
                    Le    + ++la++ Pe    +++ +l+e+      + + +        
  gi|1697843   557 ILENIFRHVHSLAKSHPESVSQEFRARLREIAADRPLSLR-P-------- 597  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                   +dLv +  ++  F+TSD  H+V TPa l ++ +L +  v+ l d a G++
  gi|1697843   598 SDLVILTGIATTFPTSDHFHAVATPAHLCLSRYLGQGAVNILADFATGAY 647  

                   LvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerd
                    +s+VL++q  SkRy Pe+++ +  +L   l p    e+     ++F   
  gi|1697843   648 AASLVLQYQLVSKRYMPELINYVLNALC-NLAP----EEPKSSLGLFPSR 692  

                   RLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsS
                      s e+          k s  l+  +L+  D +t   ++      l+ S
  gi|1697843   693 ---SPEE------SLRLKISKSLKSRKLQFWD-ITGPDSPK-AQEELKLS 731  

                   lLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkeslpekR
                   l +    ++L+ ++++ +   +AF EIf   +  L  +++s k ++p+  
  gi|1697843   732 LINT--FISLLSTASDMWSDISAFLEIFDQAQKVLRFLnrSCKGKIPSV- 778  

                   lkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDK
                   ++  l +++ ++   t  a+  r PL l  H+P+aI +  PKFE  +   
  gi|1697843   779 VQDTLQSTLDKLDGHTSKARLTRRPLLLHDHRPLAIKTAIPKFEDTF--- 825  

                   RsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEk
                    +Pdk  yDp +eR+e n Lka  KrE+KGA+RElRKDa F+ar++l Ek
  gi|1697843   826 -NPDKH-YDPNRERAEANRLKAEYKRERKGAMRELRKDANFIAREKLREK 873  

                   aakdqerhEKmkkivnelqeqegAl<-*
                      d e+  K k++v+e+q qeg +   
  gi|1697843   874 KERDAEYEKKYKRLVAEVQNQEGRE    898  

gi|242798865|ref|XP_002483256.1|: domain 1 of 1, from 41 to 904: score 506.7, E = 3e-149
                   *->keedreeKKKAvakiqkefNPFdvkv.akr.KFdilGrsKtkvKgee
                      +   r +     aki+++fNPF++k+++++ KFd+  r      g  
  gi|2427988    41    SRVQRNAT---LAKIREQFNPFEIKApSRNaKFDVTTRDGSLKAGNF 84   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV +  +ee+R+ Tl +e+  +nK g + D+R+GE+++  +     E
  gi|2427988    85 ARPGVTKSLGEERRRETLLKELHSRNKIGSIMDRRFGENDPTMT----PE 130  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.....SvK.
                   e   eRf RE   Q+++ K ++ nl D  E  +e+++ g s + +++v +
  gi|2427988   131 ERAAERFARES--QRKMRKENMFNLEDDDEEELELTHGGRSlsfgdAVAg 178  

                   DDlDsleelgeeLsdddELadeaLDkdfla.......lkrFeeeDAeaee
                   DD+ +   +gee s+d+E       k+ la++++ +++ +   eD+ea +
  gi|2427988   179 DDFAENDISGEESSEDEESSRKR--KRALAtedevddMEGMASEDDEADK 226  

                   eqrGA.kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLl
                   e +  +kK+K+EVm+E+IaKSKlyK Er+K+Ke   Dl+ +LD+    + 
  gi|2427988   227 ETEPLrKKTKAEVMKEVIAKSKLYKYERQKAKEDDDDLRAELDKGLPEIF 276  

                   sllamekltsRKsGiKkpreaked...................tDaeYDl
                    l    k++      K+p  +ked    ++++    +++++++ D eYD+
  gi|2427988   277 DLMRGVKPA----PSKQPEAPKEDaammnpdraallngkdrteADIEYDK 322  

                   llkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEled
                    lk M f+k  +P+dRTKTeEE Aq+Eae+L  LE eRl+RM+++e  ++
  gi|2427988   323 RLKQMAFDKKSAPTDRTKTEEERAQEEAERLKRLELERLRRMRGDED-SE 371  

                   gEeEiGGEESvkklkvrSvdDLdD....sfsVEEDKPKfGfiedlleRED
                   +E+             +  +D++D++++ + + +D   fG    ++    
  gi|2427988   372 SEA-------------GRDEDEQDeeegADFIPDDAKAFGLTSAVET--- 405  

                   NvdNeEddEdddeeaedsd..DddsvndGtdlkqkKeavLkddEneDDdL
                       e d Ed+d+ + d d  D ds  d               E++D ++
  gi|2427988   406 EPRRELDVEDEDDFIIDDDlvDMDSNAD------------LSFEESDEEM 443  

                   GAELEDkeGeeDdEeDedEESDaEldvlkdLKede.aqplkgeaikasvk
                   G  LED+e  eD++  +dE         k LK+  + q+     +     
  gi|2427988   444 GG-LEDEE-SEDEGLMDDEF-------TKSLKNLVgTQSGSNDVPTTG-- 482  

                   eKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVe
                         Ks d         +++t++cP th+e+l+ lk+    D p IV+
  gi|2427988   483 ------KSTDA--------LAYTYPCPQTHDEFLAILKDTTARDIPVIVQ 518  

                   RIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqL
                   RI+ ++hp L+ +N K kl+ Fs vL  h+   +  +++Q   +   f  
  gi|2427988   519 RIRALYHPRLHSDN-KVKLGVFSKVLVEHV--AY--MANQHGSET--FNI 561  

                   LekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl.
                    e L  + +++a+ ++e  a  ++  l+ +  e       +     +Sl 
  gi|2427988   562 VENLLRHIHSMAKTNSEPVAHAFRDHLRRMATE------RP-----LSLl 600  

                   .kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGl
                   + dLv +  v   F+TSD  H+VvTPa l +a +L +s vs   d   G+
  gi|2427988   601 pADLVILTGVMTVFPTSDHFHPVVTPANLCIARYLGQSTVSGAPDLVAGA 650  

                   fLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFer
                   +L+++ L++q   kRy Pe v+    +L  ll p   V +     L  e 
  gi|2427988   651 YLATLALEYQTLAKRYMPEFVNYCLNALC-LLSP-TPVSQQVGFVLMRES 698  

                   dRLDslekGLPldnlfavkestll.epqrLslaDLVtqtitee..fpvda
                       sl +          k s++++ ++r    D     i  +++ ++ +
  gi|2427988   699 K--ESLRL----------KSSSIDsDIHRIGFWD----IIADDgtASSED 732  

                   lrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsry..slkesl
                   l+  l +    ++L+  + + +   +AF E f P    L  +++s  +s 
  gi|2427988   733 LKINLINT--FISLLDAAADLWSDKSAFTETFTPAKSILKHLkkSFAKSA 780  

                   pekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEn
                    +k l+  l  ++ ++       +  r PL l +H+P+aI    PKFEE 
  gi|2427988   781 SSKPLSIQLTTTLHKLNTHLTQSHHHRRPLLLHNHRPLAIKQSIPKFEED 830  

                   yDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlR
                   +    +Pdk  yDp +eR+elnKLka +KrE+KGA+RElRKDa Fvar+ 
  gi|2427988   831 F----NPDKH-YDPNRERAELNKLKAEHKRERKGAMRELRKDANFVAREQ 875  

                   lkEkaakdqerhEKmkkivnelqeqegAl<-*
                   l Ek  kd ++  K +++ +e+q +eg +   
  gi|2427988   876 LREKKEKDAAYEKKYRRLIAEIQGEEGRE    904  

gi|291188514|gb|EFE43850.1|: domain 1 of 1, from 37 to 876: score 505.9, E = 5.3e-149
                   *->keedreeKKKAvakiqkefNPFdvkv.ak..rKFdilGrsKtkvKge
                        e r     A + i+++fNPF+v+++a++++ +  l  s     + 
  gi|2911885    37    AAENRVKRNAALQAIREQFNPFEVRApARpsNLYIYLATSEANHQIL 83   

                   eGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                                +Rk+Tl +e++ +nK g+ +D+R+GE+++  +     
  gi|2911885    84 -------------QRKQTLLKELQSRNKVGGLLDRRFGENDPSMT----P 116  

                   EeKMleRfsRErmSQlrLSKre.aynlnDGlEDveedGdrggsSvKDDlD
                   E    eR+ RE   Q r SK+e++ nl D +E    ++++g+s    D D
  gi|2911885   117 EQRAAERYARES--QKR-SKKEgLFNLEDEEEEEMQLTHMGQS--LFDVD 161  

                   sle.elgeeLsdddELadeaLDkdflal........krFeeeDAeaeeeq
                    + +   e+Ls  +E+ d ++ k ++   ++ ++ ++    + +e e++ 
  gi|2911885   162 AGKdDFNEDLSGLEEESDGEIGKKRKRIleevddmeGMADNDEDEEEQPE 211  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll
                   r  kKsK EVm+EiIaKSK yK Er+K Ke    l+  LD    d+    
  gi|2911885   212 R--KKSKNEVMKEIIAKSKQYKYERQKSKEDDNELRAILDQGLPDVFAMM 259  

                   amekltsRKsGiKkpreaked.................tDaeYDlllkEM
                     +k +      K   ++++++ ++++    ++++++  D eYD  lk M
  gi|2911885   260 RGTKAA--DPKPKPAPVPEPPqmdpdraallggkdrdvADREYDQRLKQM 307  

                   vfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEi
                    f+kR +PsdRTKTeEE+  +Ea +L eLE+eRl+RM++ eE +d+E   
  gi|2911885   308 AFDKRSKPSDRTKTEEEKIEEEAKRLQELENERLRRMRGEEE-SDEEP-- 354  

                   GGEESvkklkvrSvdDLdDsfsVEEDKPKfGfie.....dlleREDNvdN
                                 +  +D +s  +D   fG  +++++++l      v+ 
  gi|2911885   355 --------VENAAEEEPQD-DSEPDDAKAFGLAQpetsnGLFG----VED 391  

                   eEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELED
                   e d+  dd++   + +   v+         e   +  E+eDD      +D
  gi|2911885   392 EDDFIIDDDLVDNESG-ADVSF-------TESDVESEEEEDDA-----DD 428  

                   keGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKK
                   +e ++ d e+                 + +     +a++ s         
  gi|2911885   429 TE-FVGDLELPKDR------------PSASGGTTSKAPSDS--------- 456  

                   sadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahh
                              s++Ft++cP +h+ +l+ lk+ d e  p +V+RI+ +hh
  gi|2911885   457 -----------SLAFTYPCPESHDQFLQILKGVDIENTPVVVQRIRALHH 495  

                   pKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLvea
                     L+++N K kl+ Fs +L  h    +  l++   +    f   e    +
  gi|2911885   496 ASLHPDN-KVKLGEFSKILVDHA--VY--LANKTPRPS--FAIVESVLRH 538  

                   LielaqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkL
                    +++a+  Pe  a  ++ +l++ i+e       +        +dLv++  
  gi|2911885   539 VHSMAKTYPEEVATRFRAQLRD-ISENRPLGLLP--------GDLVLLTG 579  

                   vgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkf
                   v+ +F+TSD  H+VvTP++l+m  +L + pv+Sl dIa G++++s+ L++
  gi|2911885   580 VATIFPTSDHFHAVVTPSILTMGRYLGQGPVNSLNDIATGAYIASLCLQY 629  

                   qsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekG
                   q +SkRy+Pe ++++   L   l p    ++    P+ F       l + 
  gi|2911885   630 QTYSKRYIPEFMNFILNSLT-ILAP----KESKSNPGFFPAR----LPE- 669  

                   LPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvl
                      +       ++   + +L+  D +  t +       l+ SlL+i   +
  gi|2911885   670 --VQLRLQLDKVSSKDLRKLQFWD-IFSTSLNGSDAENLKLSLLNI--LV 714  

                   eLvEeiveiyyklqAFiEIflP....IlaLLsryslkeslpekRlkekll
                    L+  + e +++  +  EIf P ++ I+      +    lp+  l+ +l 
  gi|2911885   715 TLLDKAAELWGSKLSSLEIFEPassvIQHVIESCPK-AALPSA-LSTHLR 762  

                   davelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdks
                     ++ +  l ++ k+ r PL l +H+P+aI +  PKFEE +    +Pd  
  gi|2911885   763 RSLKTIKALLASCKRDRRPLLLHNHRPLAIKSSIPKFEESF----NPDRH 808  

                   SyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqe
                    yDpD+eR+el KLka +KrEkKGA+RElRKDa F+ar+ l Ek   d e
  gi|2911885   809 -YDPDRERAELSKLKAEHKREKKGAMRELRKDANFIARESLREKKERDAE 857  

                   rhEKmkkivnelqeqegAl<-*
                   +  K +++v+e+q +eg +   
  gi|2911885   858 YERKYRRLVAEIQGEEGRE    876  

gi|255954791|ref|XP_002568148.1|: domain 1 of 1, from 37 to 897: score 504.7, E = 1.2e-148
                   *->keedreeKKKAvakiqkefNPFdvk.vak.rKFdilGrsKtkvKgee
                      +   r     A + i+ +fNPF++k+ +k+ KFd+  r      g  
  gi|2559547    37    GAKNRNQREIALQAIRDRFNPFEIKtINKsSKFDVTTRDGNTTAGGG 83   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV +  +ee+R+ Tl +e   +nK g+ +D+R+GE+++  +     E
  gi|2559547    84 ARPGVTKSLGEERRRATLLKEMNSRNKVGGLVDRRFGENDPTMT----PE 129  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e   eRf RE   Q+++ K ++ nl D  ED   ++++g+s     +D+ 
  gi|2559547   130 ERAAERFARES--QRKMRKESMFNLEDEDEDGMQLTHMGQS---LSFDGP 174  

                   eelgeeL.sdddELadeaLDkdflal...krFeeeDAe.....aeeeqrG
                    + ++e ++++d + de++   ++  +++  + + D e+  + + eeq G
  gi|2559547   175 NQDDFEAgDLEDAESDEEMSRKRKRIpddDENQDQDQEdfidyGDEEQPG 224  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                    kK+K+EVm+E+IaKSK+yKaEr+ +K+  eDl+++LD+   dL   l  
  gi|2559547   225 RKKTKAEVMKEVIAKSKFYKAERQQAKDDDEDLREELDKELPDLFEALRG 274  

                   ekltsR.................KsGiKkpreakedtDaeYDlllkEMvf
                    k+ +++ +++ ++++ ++ +++++ + ++     d+ +eYD  l+ M f
  gi|2559547   275 IKPSAKpakpeapkqdfsemnpeRAAMLEESQNSKDPEKEYDQRLRQMTF 324  

                   ekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGG
                   + R +P+dRTKTeEE+A +Eae+L +LE+ Rl+RM++ +   d+E     
  gi|2559547   325 DQRSKPTDRTKTEEEKAEEEAERLKKLENDRLRRMRGEQLTDDEED---- 370  

                   EESvkklkvrSvdD..LdDsfsVEEDKPKfGfiedlleREDNvdNeEddE
                               +D+ LdD  s  +D   fG        E   + + +dE
  gi|2559547   371 ---------NMDEDeiLDDDESEIDDATHFGLPA--YPTETRPELGVEDE 409  

                   dddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGee
                   dd    ed+   +s  +             d  ++D +   E ED +  e
  gi|2559547   410 DDFIIDEDLVETNSNAS------------LDMGDSDME---EEEDSSSDE 444  

                   DdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTi
                    d+ D   E          L +    p   +a   +v e        +T 
  gi|2559547   445 SDGPDGEDE----------LINGMTLPAEDSAAASTVAEVS-----KET- 478  

                   PASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLke
                       +  ++Ft++cPk he +l+  k  + e  p++++R++ +hhp Lk+
  gi|2559547   479 ----NGKLAFTYPCPKDHESFLAITKNVAVEEIPTVIQRVRALHHPRLKP 524  

                   eNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLiela
                   +N K kl+ F  vL  h+   +  + +     +  f  Le    + ++la
  gi|2559547   525 GN-KDKLGRFAEVLIEHV--SY--MGNKTEQPP--FAILENIIRHIHSLA 567  

                   qelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllF
                   +  P    i  + +l+e+ ke       +     +  +dL+++   +  F
  gi|2559547   568 KTHPLNVTIACRAQLREIGKE------RP---LNLLPGDLILLTGLSTFF 608  

                   sTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSk
                   +TSD  H   TPa l +a +L ++   Sl d a G f +s+ L++q  Sk
  gi|2559547   609 PTSDHFHTTATPAHLCLARYLGQCTTTSLADLASGTFAASLCLQYQQVSK 658  

                   RyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldn
                   Ry Pe v+    +L   l p     + s + + F  +    + k    + 
  gi|2559547   659 RYMPEFVNYTLNALC-NLAP----TEPSAKFGAF--P----YRK---SQE 694  

                   lfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEe
                        +s ++ p +L   D Vt   +       l+ SlL     ++L+  
  gi|2559547   695 SVQLVPSRKVTPRKLRFRD-VTTSSSDPQAQEELKISLLAT--LVSLLGS 741  

                   iveiyyklqAFiEIflPIlaLLsry..slkeslpekRlkeklldavelve
                   +++i+   +AF EIf P+ a L+ +++slk +      +e + + + ++ 
  gi|2559547   742 ASDIWAEKSAFTEIFTPVRAVLQYLrqSLKAKVYAA-AQEPIQSNLDKID 790  

                   KltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDke
                      + a+  r PL l  HKP+aI +  PKFEEn+    +Pdk  yDpD+e
  gi|2559547   791 SHLAQARLVRRPLFLHDHKPLAIKTAIPKFEENF----NPDKH-YDPDRE 835  

                   RselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkk
                   R+e n Lk+  KrE+KGA+RElRKDa+Fvar+ l Ek   d e+  K k+
  gi|2559547   836 RAESNRLKKEFKRERKGAMRELRKDASFVAREQLREKKERDAEYEKKYKR 885  

                   ivnelqeqegAl<-*
                   +v+e+q qeg     
  gi|2559547   886 LVAEIQSQEGRA    897  

gi|258575579|ref|XP_002541971.1|: domain 1 of 1, from 40 to 881: score 502.8, E = 4.4e-148
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     ++ +++fNPF+ +   r+ KF +    K      +
  gi|2585755    40    GRIHRNAV---LQELREQFNPFEARTPARpaKFAVTTN-KGTSDPVR 82   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV R+ +e++Rk Tl +e   +nK g  +D+R+GE+++  +     E
  gi|2585755    83 HRPGVTRGLGEQRRKETLLKEIHSRNKIGILVDRRFGENDPTMT----PE 128  

                   eKMleRfsRErmSQlrLSKreaynlnD..GlEDveedGdrggsSvKDDlD
                   e   eRf RE   Q+rL K ++ nl D++ +E v+++G   ++     +D
  gi|2585755   129 ERAAERFARES--QRRLKKESMFNLEDdeDEEMVLTHGGQTLT-----FD 171  

                   sleelgeeLsd..ddELadeaLDkdflalkrFeeeDA..........eae
                   +    ++e +d ++ E++de+     +  kr  eeD+ ++  + +++e++
  gi|2585755   172 ETAGDDFEEDDlnGSEEDDES--GKEKKRKRLVEEDDmeglaeasdeEGQ 219  

                   eeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLl
                    e++   KsK+EVm+E+IaKSK yK Er+K+Ke   Dl+  LD+    L 
  gi|2585755   220 PERK---KSKQEVMKEVIAKSKMYKYERQKAKEDDDDLRATLDKGLPTLF 266  

                   sllamekltsRKsGiKkpreakedt................DaeYDlllk
                        +kl        +++ +++  ++++    +++++++ D+eYD  lk
  gi|2585755   267 EVMRNTKLP---EPPRQEQAPEPTMnpdraallngkdretaDKEYDQRLK 313  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEe
                    Mvf+kR +Ps+RTKTeEE+A  Ea +Lr LE eRl+RM++    e  + 
  gi|2585755   314 QMVFDKRSKPSERTKTEEEIAEDEATRLRQLEVERLRRMQGEDDEESADD 363  

                   EiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEd
                                r +d + D +    D  +fG  + l  R D      d
  gi|2585755   364 -------------RDGDLEEDADAN--DAMQFGLHQ-LTTRPDL-----D 392  

                   dEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeG
                    Ed+d+ + d+d  +  +              d   +D d      D + 
  gi|2585755   393 VEDEDDFILDEDLIETGSA------------VDLSFSDSD----AHDSS- 425  

                   eeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsad
                   eeD +e +d E            +    p   e i       +     + 
  gi|2585755   426 EEDKGENDDDE----------FINGLTLPPGAERIGTD-RGET-----SP 459  

                   TiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKL
                         d s+++t++cP th+e+l+ lk+   +D p++V+RI+ +hhp L
  gi|2585755   460 E-----DPSLAYTYPCPETHDEFLAILKDVKMDDLPTVVQRIRALHHPRL 504  

                   keeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLie
                    e+N K kl+KFs +L  h+   +  l++Q+      f  Le L  + ++
  gi|2585755   505 SEGN-KAKLGKFSKILVEHV--TY--LANQPEAPS--FTVLESLLRHIHS 547  

                   laqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgl
                   la++ Pe   i ++  l+e+      +   +     +  +dL+ +  ++ 
  gi|2585755   548 LAKSHPEDVSIGFRAHLREM------AVDRP---VSLLPGDLIILTGIST 588  

                   lFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsi
                   +F+TSD  H+V TPa+l m  +L +  +++l d   G +  s+ L++q  
  gi|2585755   589 IFPTSDHFHMVATPAMLSMGRYLGQHNIRTLGDLVTGTYVTSLCLQYQTL 638  

                   SkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPl
                   SkRy+Pe+ + +  +L   l p        +   +   +     ++ + l
  gi|2585755   639 SKRYIPELANYVLNALC-ILAP--TSPKTGLGSFPVRMP-----SEPMRL 680  

                   dnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLv
                     + + +e+t+        a      ++e+     l+ Sl       + +
  gi|2585755   681 GSVNEATEITKPQFWDIL-AN---SSLSED-QAESLKLSLIKT--LTSIL 723  

                   EeiveiyyklqAFiEIflPIlaLLsry..slkeslpekRlkeklldavel
                    +++  +   +AF E+f P +a L  +  s   +lp   l+ ++  +   
  gi|2585755   724 GTASALWATKSAFYEVFDPAQAVLKHLmaSCAGKLPTV-LSDHIQQVYSD 772  

                   veKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpD
                   v     +a+  r PL l +HKP+aI +  PKFEE +    +Pdk  yDpD
  gi|2585755   773 VKLRLSEARHSRRPLLLHNHKPLAIKTAIPKFEESF----NPDKH-YDPD 817  

                   keRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKm
                   +eR+elnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+  d e+  K 
  gi|2585755   818 RERAELNKLKAEHKRERKGAMRELRKDANFIARESLREKRERDAEYERKY 867  

                   kkivnelqeqegAl<-*
                   +++v+e+q +eg +   
  gi|2585755   868 RRLVAEIQSEEGRE    881  

gi|291178786|gb|EFE34574.1|: domain 1 of 1, from 37 to 851: score 500.5, E = 2.2e-147
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        e r     A + i+++fNPF+                        
  gi|2911787    37    AAENRVKRNAALQAIREQFNPFE------------------------ 59   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                              Rk+Tl +e++ +nK g+ +D+R+GE+++  +     E  
  gi|2911787    60 -----------RKQTLLKELQSRNKVGGLLDRRFGENDPSMT----PEQR 94   

                   MleRfsRErmSQlrLSKre.aynlnDGlEDveedGdrggsSvKDDlDsle
                     eR+ RE   Q r SK+e++ nl D +E    ++++g+s    D D + 
  gi|2911787    95 AAERYARES--QKR-SKKEgLFNLEDDEEEEMQLTHMGQS--LFDVDAGK 139  

                   .elgeeLsdddELadeaLDkdflal........krFeeeDAeaeeeqrGA
                   +   e+Ls  +E+ d++  k ++   ++ ++ ++   ++ +e e++ r  
  gi|2911787   140 dDFNEDLSGLEEESDAETGKKRKRIleevddmeGMADDDEDEDEQPER-- 187  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                   kKsK EVm+EiIaKSK yK Er+K Ke    l+  LD    d+      +
  gi|2911787   188 KKSKNEVMKEIIAKSKQYKYERQKSKEDDNELRAILDQGLPDVFAMMRGT 237  

                   kltsRKsGiKkpreaked......................tDaeYDlllk
                   k +       +p +a  + +++++ ++++    ++++++  D eYD  lk
  gi|2911787   238 KAA-------EPKPAPAPvpgppqmdpdraallggkdrdvADREYDQRLK 280  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEe
                    M f+kR +PsdRTKTeEE+  +Ea +L eLE+eRl+RM++ eE +d+E 
  gi|2911787   281 QMAFDKRSKPSDRTKTEEEKIEEEAKRLQELENERLRRMRGEEE-SDEEP 329  

                   EiGGEESvkklkvrSvdDL.dDsfsVEEDKPKfGfiedlleREDNvdNeE
                                  v+ +++D +s  +D   fG  +   e   N   + 
  gi|2911787   330 -----------VENAVEEEpQD-DSEPDDAKAFGLAQ--PE-TSNGLFGV 364  

                   ddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDke
                   +dEdd     d+ D++sv d                ++D +       +e
  gi|2911787   365 EDEDDFIIDDDLVDNESVAD------------VSITESDVE------SEE 396  

                   GeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsa
                    eeDd  D  +  D E              l++  ++as           
  gi|2911787   397 -EEDDADDTEFIGDLE--------------LPKDRPSAS---------GG 422  

                   dTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpK
                    T  A  d s++Ft++cP +h+ +l+ lk+ d e  p +V+RI+ +hh  
  gi|2911787   423 TTFKAPNDSSLAFTYPCPESHDHFLQILKGVDIENTPVVVQRIRALHHAS 472  

                   LkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLi
                   L+++N K kl+ Fs +L  h    +  l++   +    f   e    + +
  gi|2911787   473 LHPDN-KAKLGEFSKILVDHA--VY--LANKTTRPS--FAIVESVLRHVH 515  

                   elaqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvg
                   ++a+  Pe  a  ++++l++ i+e       +        +dLv++  v+
  gi|2911787   516 SMAKTYPEEVAARFRSQLRD-ISENRPLGLLP--------GDLVLLTGVA 556  

                   llFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqs
                    +F+TSD  H+VvTP++l+m  +L + pv+Sl dIa G++++s+ L++q 
  gi|2911787   557 TIFPTSDHFHAVVTPSILTMGRYLGQGPVNSLNDIATGAYIASLCLQYQT 606  

                   iSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLP
                   +SkRy+Pe ++++   L   l p    ++    P++F       l +   
  gi|2911787   607 YSKRYIPEFMNFILNSLT-ILAP----KESKSNPGLFPVR----LPE--- 644  

                   ldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleL
                    +       +    + +L+  D +  t +       l+ SlL+i   + L
  gi|2911787   645 VQLRLQLDKVCSKDLRKLQFWD-IFSTSLNGSDAENLKLSLLNI--LVTL 691  

                   vEeiveiyyklqAFiEIflPIlaLLsrysl...keslpekRlkeklldav
                   +  + e ++   +  EIf P +  L+    + +k  lp+  l+ +l   +
  gi|2911787   692 LDKAAELWGTKLSSLEIFEPASSVLQHVIEscpKAALPSA-LSTHLRRSL 740  

                   elveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyD
                   + +  l ++ kk r PL l +H+P+aI +  PKFEE +    +Pd   yD
  gi|2911787   741 KTIKALLASCKKDRRPLLLHNHRPLAIKSSIPKFEESF----NPDRH-YD 785  

                   pDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhE
                   pD+eR+el KLka +KrEkKGA+RElRKDa F+ar+ l Ek   d e+  
  gi|2911787   786 PDRERAELSKLKAEHKREKKGAMRELRKDANFIARESLREKKERDAEYER 835  

                   KmkkivnelqeqegAl<-*
                   K +++v+e+q +eg +   
  gi|2911787   836 KYRRLVAEIQGEEGRE    851  

gi|51467886|ref|NP_001003831.1|: domain 1 of 1, from 13 to 850: score 498.9, E = 6.7e-147
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                          r +K  A  +iq   NPF+vk +++KFd+lGr   k K+++G 
  gi|5146788    13    ADKVRRSK--AAPEIQR--NPFEVKINRKKFDVLGR---KSKHDVGL 52   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR +a +kRk Tl +e+k+k Ks+ fiD+R+GE +  L      EeK
  gi|5146788    53 PGVSRSRANQKRKETLLKELKVKGKSNKFIDRRFGEYDSKLN----PEEK 98   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    l Rf+ Er  Q+    r   nln     +e +++ g+s     l+ +  
  gi|5146788    99 ILQRFTLER--QRLHDRRDVFNLN----EDEQLTHYGQS--LAELEKMPD 140  

                   lgeeLsdddE..LadeaLDkdflalkrFee.....eDAeaeeeqrGAkKs
                   l ++ sd +E++L +++     +++++ ++  ++++ A + eeq+    s
  gi|5146788   141 LQDSDSDSEEkgLLSAE--LTATHFGGGGGllrkkSSADGDEEQK--PRS 186  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                    +  +eE I KSK  K Er+ +Kee   l++kLD +  d++slla   +t
  gi|5146788   187 RQQLIEELILKSKQEKRERQTQKEEAQELTEKLDQQWRDIQSLLA--HKT 234  

                   sRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEa
                           +++ k+ +D  YD  ++E+ fe  A+Ps+++K  EE A +  
  gi|5146788   235 --PNAERREQPDKPQLDP-YDMAVRELGFEMKAQPSEKLKSAEEEAREQQ 281  

                   ekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV
                    +L  LE  RlkRM  ++E   +E+      S    +++S+dD  D f  
  gi|5146788   282 RRLQDLEADRLKRM--MGE---SEA------SAHTHTHISADDINDGFIL 320  

                   EEDKP.....KfGfi....edlleREDNv.......dNeEddEdddeeae
                   + DK ++ + K G ++ ++e+ +e ED    ++++++ eE+dEd   e e
  gi|5146788   321 DGDKRntltyKDGKWsmggEEEEEEEDETaarggeeEEEEEDEDAEGEEE 370  

                   dsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDed
                   +++D+d++ d +dl+       ++ E++DDd         G +D+E++ d
  gi|5146788   371 EEEDEDGEDD-GDLQS------EGAEDDDDD---------GDDDEEQLRD 404  

                   EESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrs
                   E              +e  p   e  k +  e A                
  gi|5146788   405 ED-------------EEDPPAETEEQKTEAQEAA-------------RAE 428  

                   ipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKekl
                   +p+t+  P ++ el   l + + e+  lIV RI k+hhp L+  N K+kl
  gi|5146788   429 LPYTFTAPESYSELQCVLQGRSSEQQRLIVDRIVKCHHPSLATAN-KSKL 477  

                   vKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPekl
                     +  +LL +I       se+    +  +   + L + L +l q +P ++
  gi|5146788   478 QRLFGFLLEYI-------SELTTHNPPDLRTVNTLIPQLCSLCQMFPDAA 520  

                   aislseellevikelaeey.kknEhikyPSlkdLvfFkLvgllFsTSDfr
                          + ++   + e  ++k      P l+ Lv++k+++llF+TSDfr
  gi|5146788   521 CKAVQTLISDTTHTMEETLeVKG-RAAMPGLDMLVLLKITALLFPTSDFR 569  

                   HlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   H+V TPa+l +++ L ++ v Sl d+++Gl L+ + L+f+s S R+ Pe+
  gi|5146788   570 HPVTTPAFLYISQTLTKCAVVSLEDVCKGLILCCLALEFVSLSQRFFPEL 619  

                   vyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavke
                   +++l + L  l vp  D      t  t  r R     +   l+ +     
  gi|5146788   620 INFLLGLLN-LAVP--DKTSTGYTVVTACRARGKNCDL--LLLTDTDASH 664  

                   stllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyy
                   s   +p  L ++       t +   d +r S   +   l L+   v  y+
  gi|5146788   665 SWRRKPLSLHTTH------TSAEDRDHCRLSVIDS--CLDLLKRCVSLYK 706  

                   klqAFiEIflPIlaLLsr.yslkeslpekRlkeklldavelveKltedak
                    l++F  If PI aLL+++++  e++p   ++  +  ++ ++ +      
  gi|5146788   707 ELPSFSHIFQPIRALLHKhLPV-EKYPAC-IQDLHREVLDAIPDQPS--- 751  

                   kerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKL
                    ++ PL  +++KP+ + l  PK     D  +  +       +e  e+  L
  gi|5146788   752 -QHAPLVFKKKKPIPLKLFTPKIVQILDYGKKRGNT-----REEKERERL 795  

                   kaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqe
                   k+k KrE KGA RE+RKD++F a ++l      d er  K+k ++  l +
  gi|5146788   796 KHKYKREFKGALREIRKDTRFLAQEKLNHIISRDTERKRKVKELYGSLAT 845  

                   qegAl<-*
                   qeg+    
  gi|5146788   846 QEGEW    850  

gi|55249633|gb|AAH85643.1|: domain 1 of 1, from 13 to 851: score 497.2, E = 2.3e-146
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                          r +K  A  +iq   NPF+vk +++KFd+lGr   k K+++G 
  gi|5524963    13    ADKVRRSK--AAPEIQR--NPFEVKINRKKFDVLGR---KSKHDVGL 52   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR +a +kRk Tl +e+k+k Ks+ fiD+R+GE +  L      EeK
  gi|5524963    53 PGVSRSRANQKRKETLLKELKVKGKSNKFIDRRFGEYDSKLN----PEEK 98   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    l Rf+ Er  Q+    r   nln     +e +++ g+s     l+ +  
  gi|5524963    99 ILQRFTLER--QRLHDRRDVFNLN----EDEQLTHYGQS--LAELEKMPD 140  

                   lgeeLsdddE..LadeaLDkdflalkrFee.....eDAeaeeeqrGAkKs
                   l ++ sd +E++L +++     +++++ ++  ++++ A + eeq+    s
  gi|5524963   141 LQDSDSDSEEkgLLSAE--LTATHFGGGGGllrkkSSADGDEEQK--PRS 186  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                    +  +eE I KSK  K Er+ +Kee   l++kLD +  d++slla   +t
  gi|5524963   187 RQQLIEELILKSKQEKRERQTQKEEAQELTEKLDQQWRDIQSLLA--HKT 234  

                   sRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEa
                           +++ k+ +D  YD  ++E+ fe  A+Ps+++K  EE A +  
  gi|5524963   235 --PNAERREQPDKPQLDP-YDMAVRELGFEMKAQPSEKLKSAEEEAREQQ 281  

                   ekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV
                    +L  LE  RlkRM  ++E   +E+      S    +++S+dD  D f  
  gi|5524963   282 RRLQDLEADRLKRM--MGE---SEA------SAHTHTHISADDINDGFIL 320  

                   EEDKP.....KfGfi....edlleREDNv.......dNeEddEdddeeae
                   + DK ++ + K G ++ ++e+ +e ED    ++++++ eE+dEd   e e
  gi|5524963   321 DGDKRntltyKDGKWsmggEEEEEEEDEAaargggeEEEEEDEDAEGEEE 370  

                   dsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDed
                   +++D+d++ d +dl+       ++ E++DDd      D    e++ +D+d
  gi|5524963   371 EEEDEDGEDD-GDLQS------EGAEDDDDD------DGDEDEEQLRDKD 407  

                   EESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrs
                   EE                 p   e  k    e A                
  gi|5524963   408 EE---------------DPPAETEEQKTDAQEAA-------------RAE 429  

                   ipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKekl
                   +p+t+  P ++ el   l + + e+  lIV RI k+hhp L+  N K+kl
  gi|5524963   430 LPYTFTAPESYSELQCVLQGRSSEQQRLIVDRIVKCHHPSLATAN-KSKL 478  

                   vKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPekl
                     +  +LL +I       se+    +  +   + L + L +l q +P ++
  gi|5524963   479 QRLFGFLLEYI-------SELTTHNPPDLRTVNTLIPQLCSLCQMFPDAA 521  

                   aislseellevikelaeey.kknEhikyPSlkdLvfFkLvgllFsTSDfr
                          + ++   + e  ++k      P l+ Lv++k+++llF+TSDfr
  gi|5524963   522 CKAVQTLISDTTHTMEETLeVKG-RAAMPGLDMLVLLKITALLFPTSDFR 570  

                   HlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   H+V TPa+l +++ L ++ v Sl d+++Gl L+ + L+f+s S R+ Pe+
  gi|5524963   571 HPVTTPAFLYISQTLTKCAVVSLEDVCKGLILCCLALEFVSLSQRFFPEL 620  

                   vyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavke
                   +++l + L  l vp +      ++  +F     +     L l+ +     
  gi|5524963   621 INFLLGLLN-LAVPDKTSTGYTVVS-PFRAR--GKNCD-LLLLTDTDASH 665  

                   stllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyy
                   s   +p  L ++       t +   d +r S   +   l L+   v  y+
  gi|5524963   666 SWRRKPLSLHTTH------TSAEDRDHCRLSVIDS--CLDLLKRCVSLYK 707  

                   klqAFiEIflPIlaLLsr.yslkeslpekRlkeklldavelveKltedak
                    l++F  If PI aLL+++++  e++p   ++  +  ++ ++ +      
  gi|5524963   708 ELPSFSHIFQPIRALLHKhLPV-EKYPAC-IQDLHREVLDAIPDQPS--- 752  

                   kerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKL
                    ++ PL  +++KP+ + l  PK     D  +  +       +e  e+  L
  gi|5524963   753 -QHAPLVFKKKKPIPLKLFTPKIVQILDYGKKRGNT-----REEKERERL 796  

                   kaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqe
                   k+k KrE KGA RE+RKD++F a ++l      d er  K+k ++  l +
  gi|5524963   797 KHKYKREFKGALREIRKDTRFLAQEKLNHIISRDTERKRKVKELYGSLAT 846  

                   qegAl<-*
                   qeg+    
  gi|5524963   847 QEGEW    851  

gi|226290909|gb|EEH46337.1|: domain 1 of 1, from 40 to 891: score 494.0, E = 2.1e-145
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     a i+++fNPF+vk   r+ KF    r         
  gi|2262909    40    NKIQRNAA---LAGIRERFNPFEVKTPSRpaKFSFASR--SNHEAPQ 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e   + K g  +D+R+GE+++  +     E
  gi|2262909    82 SRPGVTKGLGEQRRKETLLKEMHRRGKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e  +eRf RE   Q +L K +  nl   +ED  e++++g+  + D  D+ 
  gi|2262909   128 ERAVERFARES--QKKLKKESVFNLE-DEEDEIELTHLGQALIFDKEDGD 174  

                   eelgeeLsdddELadeaLDkdflalkrFeeeDAea.....eeeq...rGA
                       ++L   dE  d      ++     ee+D e+  +++eee++++r  
  gi|2262909   175 DFHEDDLNGSDEDGDSG--IARKRRRLVEEDDMEGladdsEEEGppeR-- 220  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                   kKsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+    +  +++m 
  gi|2262909   221 KKSKNEVMKELIAKSKFHKYERQKAKEDDDDLRATLDKGLPEI--FEMMR 268  

                   kltsRKsGiKkpre..akedt....................DaeYDlllk
                    ++      K + e+ +k+d+  + ++++    +++++++ D+eYD  lk
  gi|2262909   269 GVK------KPEPEslPKPDLiatmnpdraallngkdrdqaDKEYDQRLK 312  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMe.eteEledgE
                    + fekRA+P dRTKTeEE A +EaekL  LE eRl+RM++e  E ++ E
  gi|2262909   313 QLAFEKRAKPLDRTKTEEERAEEEAEKLKQLEKERLRRMQgENDESSENE 362  

                   eEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeE
                   e             r   D+       +D   fG  +     E  v+ eE
  gi|2262909   363 E---------NASDREMGDESE----RDDAKAFGLAQPSSVTELGVE-EE 398  

                   ddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDke
                   dd  +d+   +sd +   ++                +e D   A   D+e
  gi|2262909   399 DDFIIDSDLVESDSEADLSL----------------DESDI--ASSADEE 430  

                   GeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsa
                    e +d eDe                  +  l+  a  + +   +      
  gi|2262909   431 -ESEDKEDEFIG---------------SLVLPPDADDGKGFADT--NAGL 462  

                   dTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpK
                   +T   S +rs+++t++cP +he +l+ +    +eD p+IV+RI+ +hhp 
  gi|2262909   463 ST--VSGNRSLAYTYPCPENHEHFLQIIQAAKTEDLPTIVQRIRALHHPR 510  

                   LkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLi
                   L+++N K+kl  Fs vL qh    f  l++Q+   +  f  Le L  + +
  gi|2262909   511 LHGDN-KSKLAAFSKVLVQHT--AF--LANQPNHPP--FAVLENLLRHIH 553  

                   elaqelPeklaislseellevikelaeeykknEhikyPSl..kdLvfFkL
                   +++++ Pe  a  +++ l+e+          +     ++l ++dLv +  
  gi|2262909   554 SMTKSQPEPVATAMRNHLREMSDN------RP-----LELlpGDLVILTG 592  

                   vgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkf
                   v+ +F+TSD  H+VvTP++l m  +L +s +    d+  G++++++  ++
  gi|2262909   593 VATIFPTSDHFHAVVTPSMLAMGRYLGQSNITNIGDVVTGAYIATLCIQY 642  

                   qsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekG
                   q   kRy+Pe ++ +  +L   l p     + + t + F      +    
  gi|2262909   643 QTLAKRYIPEFINYVLNALC-ILAP----SEPQTTFGFFPIR--KPTAS- 684  

                   LPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvl
                     l  +   k s+  ++ +    D+              + SlL+    +
  gi|2262909   685 --LRIITPSKLSSSAPIRKPAFWDILSDSSADTVEQETIKLSLLST--FV 730  

                   eLvEeiveiyyklqAFiEIflPIlaLLsrys.....lkeslpekRlkekl
                    L+  + + + + +AF  If P    L  +s++ +++  s ++    +++
  gi|2262909   731 DLLDQAADLWTSKSAFCDIFSPANRVLKHLSksinnNLSSTLSD-QLRRI 779  

                   ldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdk
                    d+++++ K  +     r PL l +H+P+aI +  PKFEE +    +P  
  gi|2262909   780 CDKLQALLKQSD---LARRPLVLHNHRPLAIKTAIPKFEESF----NPHR 822  

                   sSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdq
                     yDpD+eR+ lnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+ kd 
  gi|2262909   823 H-YDPDRERAKLNKLKAEHKRERKGAMRELRKDANFIARESLREKREKDA 871  

                   erhEKmkkivnelqeqegAl<-*
                   e+  K +++v+e+q +eg +   
  gi|2262909   872 EYERKYRRLVAEIQGEEGRE    891  

gi|67521954|ref|XP_659038.1|: domain 1 of 1, from 37 to 898: score 488.9, E = 7e-144
                   *->keedreeKKKAvakiqkefNPFdvk.vakrKFdilGrsKtkvKgeeG
                      +   r+    A   i+++fNPF++++v++ KFd+  r     K + G
  gi|6752195    37    NAQNRAQRESALNAIRERFNPFEIRtVSRGKFDVTTR-DGGAKSASG 82   

                   ..kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                   +  PGV +  +ee+R++Tl +e   +nK g++ D+R+GE+++  +     
  gi|6752195    83 nfRPGVTKSLGEERRRQTLLQEMDRRNKVGGIMDRRFGENDPTMT----P 128  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggsSvKDD
                   Ee   eRf R    Q +L K ++ nl    ED+ee+ ++++ g s    D
  gi|6752195   129 EERAAERFARAS--QKKLRKDSMFNLE---EDDEEeftLTHKGESLSFGD 173  

                   lDsle.elgeeLsdddELadeaLDkdflalkrFeeeDAeaee....eqrG
                    D++ +   e+L+ +d  + e   k+       e e +  +++++ + r 
  gi|6752195   174 EDGIRdDFQEDLDAGDMSDTEMPRKRKRFIDDPEAEEDGSQDgedvPER- 222  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                    kKsK EVm E+IaKSK+yKa r+ +Ke    l+++LD+    L   l  
  gi|6752195   223 -KKSKHEVMQEVIAKSKFYKAQRQMAKEDDDELREELDKGLPELFDMLRG 271  

                   ekltsRK.......sGiKkpreake......dtDaeYDlllkEMvfekRA
                    k+  ++++++++ +G+   r a+ ++++++d+ +eYD  lk + f+kR 
  gi|6752195   272 VKPPPKQeppkddlAGMNPDRAAIMqghsqgDPEKEYDQRLKQLTFDKRS 321  

                   sPsdRTKTeEElAqkEaekLreLEeeRlkRMee....teEledgEeEiGG
                    P+dRTKTeEE+A +Ea +L +LEeeR++RM++++ +  E e+ EeE  G
  gi|6752195   322 MPTDRTKTEEEKAEEEAQRLKKLEEERIRRMRGedvsEDEAEAAEEEEDG 371  

                   EES.............vkklkvrS......vdDLdDsfsVEEDKPKfGfi
                   EES++++ +++ ++ +  +++  S++++++vdD+dD            fi
  gi|6752195   372 EESeeeslpddakdfgLQQPTNYStsrpegVDDEDD------------FI 409  

                   ed..lleRED.NvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                   +d+ ++ R D      EddEd+    e+s+D                   
  gi|6752195   410 LDdlVETRSDvSLSFVEDDEDIIGSEEESED------------------- 440  

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                     E+e D+       + G    +e ++ E                +p + 
  gi|6752195   441 --EEEEDE------LINGITMPGEESGNE----------------APAPD 466  

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                     i +                      +++t++cP +hee+l  +k+ ++
  gi|6752195   467 TQIAGD--------------------GLAYTYPCPNSHEEFLKTIKDISY 496  

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   eD p++++RI+ +hhp L+ +N K kl+ F  +L qh    +  + eQ+ 
  gi|6752195   497 EDLPTVIQRIRALHHPRLHSDN-KVKLGRFAGILVQHA--AY--MVEQPQ 541  

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   + +  f   e    + ++la++ Pe     ++ +l+ev      + + + 
  gi|6752195   542 RPP--FAVVENVLRHIHSLAKSHPESVSLAFRAQLREVAADRPLSLR-P- 587  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                          +dLv +  ++ +F+TSD  H+V TPa l +a +L + pv+Sl+
  gi|6752195   588 -------GDLVILTGIATIFPTSDHFHAVSTPAHLCLARYLGQGPVNSLS 630  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   d + G + +s+ L++q iSkRy Pe  + +  +L   l p     + s +
  gi|6752195   631 DLCTGTYAASLALQYQTISKRYMPEFLNYVLNALC-ILSP----GEPSSK 675  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                    + F +    + e+    + +   k++++ ++q L            e  
  gi|6752195   676 LGSFPLR--QPTEL----LRIRPSKPLNIRKLQFLDVSA------RSEID 713  

                   vdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkes
                     +l+ Sl       +L+ ++++ + + +A  EIf   +a L+  s+   
  gi|6752195   714 PEDLKLSLITT--LSSLLNTASDLWSSKSASVEIFNQAQAVLQHVSSSCV 761  

                   lpekRlkek..............lldavelveKltedakkerKPLAlqeH
                   +  k  k k+ +++  +    ++l +++ +++      +  r PL l +H
  gi|6752195   762 DVNK--KAKkaknplipaaaldtLQSTLDKLSTVLSQSRLTRRPLLLHNH 809  

                   KPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGA
                   +P+a+ +  PKFE  +    +Pdk  yDp +eR+e n Lka  KrE+KGA
  gi|6752195   810 RPLAVKTAIPKFEDSF----NPDKH-YDPNRERAEVNRLKAEYKRERKGA 854  

                   iRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +RElRKDa F+ar++l Ek  kd e+  K k++v+e+q +eg +   
  gi|6752195   855 MRELRKDANFIAREKLREKKEKDAEYERKYKRLVAEVQNEEGRE    898  

gi|225679198|gb|EEH17482.1|: domain 1 of 1, from 40 to 891: score 488.0, E = 1.3e-143
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     a i+++fNPF+vk   r+ KF    r         
  gi|2256791    40    NKIQRNAA---LAGIRERFNPFEVKTPSRpaKFSFASR--SNHEAPQ 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e   + K g  +D+R+GE+++  +     E
  gi|2256791    82 SRPGVTKGLGEQRRKETLLKEMHRRGKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e  +eRf RE   Q +L K +  nl   +ED  e++++g+  + D  D+ 
  gi|2256791   128 ERAVERFARES--QKKLKKESVFNLE-YEEDEIELTHLGQALIFDKEDGD 174  

                   eelgeeLsdddELadeaLDkdflalkrFeeeDAea.....eeeq...rGA
                       ++L   dE  d      ++     ee+D e+  +++eee++++r  
  gi|2256791   175 DFHEDDLNGSDEDGDSG--IARKRRRLVEEDDMEGladdsEEEGppeR-- 220  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                   kKsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD+    +  +++m 
  gi|2256791   221 KKSKNEVMKELIAKSKFHKYERQKAKEDDDDLRATLDKGLPEI--FEMMR 268  

                   kltsRKsGiKkpre..akedt....................DaeYDlllk
                    ++      K + e+ +k+d+  + ++++    +++++++ D+eYD  lk
  gi|2256791   269 GVK------KPEPEslPKPDLiatmnpdraallngkdrdqaDKEYDQRLK 312  

                   EMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMe.eteEledgE
                    + fekRA+P dRTKTeEE A +EaekL  LE eRl+RM++e  E ++ E
  gi|2256791   313 QLAFEKRAKPLDRTKTEEERAEEEAEKLKQLEKERLRRMQgENDESSENE 362  

                   eEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeE
                   e             r   D+       +D   fG  +     E  v+ eE
  gi|2256791   363 E---------NASDREMGDESE----RDDAKAFGLAQPSSVTELGVE-EE 398  

                   ddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDke
                   dd  +d+   + d +   +                 +e D   A   D+e
  gi|2256791   399 DDFIIDSDLVEFDSEADLSV----------------DESDI--ASSADEE 430  

                   GeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsa
                    e +d eDe                  +  l+  a  + +   +      
  gi|2256791   431 -ESEDKEDEFIG---------------SLVLPPDADDGKGFADT--NAGL 462  

                   dTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpK
                   +T   S +rs+++t++cP +he +l+ +    +eD p+IV+RI+ +hhp 
  gi|2256791   463 ST--VSGNRSLAYTYPCPENHEHFLQIIQAAKTEDLPTIVQRIRALHHPR 510  

                   LkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLi
                   L+++N K+kl  Fs vL qh    f  l++Q+   +  f  Le L  + +
  gi|2256791   511 LHGDN-KSKLAAFSKVLVQHT--AF--LANQPNHPP--FAVLENLLRHIH 553  

                   elaqelPeklaislseellevikelaeeykknEhikyPSl..kdLvfFkL
                   +++++ Pe  a  +++ l+e+          +     ++l ++dLv +  
  gi|2256791   554 SMTKSQPEPVATAMRNHLREMSDN------RP-----LELlpGDLVILTG 592  

                   vgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkf
                   v+ +F+TSD  H+VvTP++l m  +L +s +    d+  G++++++  ++
  gi|2256791   593 VATIFPTSDHFHAVVTPSMLAMGRYLGQSNITNIGDVVTGAYIATLCIQY 642  

                   qsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekG
                   q   kRy+Pe ++ +  +L   l p     + + t + F      +    
  gi|2256791   643 QTLAKRYIPEFINYVLNALC-ILAP----SEPQTTFGFFPIR--KPTAS- 684  

                   LPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvl
                     l  +   k s+  ++ +    D+              + SlL+    +
  gi|2256791   685 --LRIITPSKLSSSAPIRKPAFWDILSDSSADTVEQETIKLSLLST--FV 730  

                   eLvEeiveiyyklqAFiEIflPIlaLLsrys.....lkeslpekRlkekl
                    L+  + + + + +AF  If P    L  +s++ +++  s ++    +++
  gi|2256791   731 DLLDQAADLWTSKSAFCDIFSPANRVLKHLSksinnNLSSTLSD-QLRRI 779  

                   ldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdk
                    d+++++ K  +     r PL l +H+P+aI +  PKFEE +    +P  
  gi|2256791   780 CDKLQALLKQSD---LARRPLVLHNHRPLAIKTAIPKFEESF----NPHR 822  

                   sSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdq
                     yDpD+eR+ lnKLka +KrE+KGA+RElRKDa F+ar+ l Ek+ kd 
  gi|2256791   823 H-YDPDRERAKLNKLKAEHKRERKGAMRELRKDANFIARESLREKREKDA 871  

                   erhEKmkkivnelqeqegAl<-*
                   e+  K +++v+e+q +eg +   
  gi|2256791   872 EYERKYRRLVAEIQGEEGRE    891  

gi|71005582|ref|XP_757457.1|: domain 1 of 1, from 43 to 964: score 487.8, E = 1.5e-143
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        e+r  K   +  i  + NPF+ kv+k K  +lGr   k Kg++G 
  gi|7100558    43    AAEARRNK---INAIVADLNPFEQKVTKPKHEVLGR---KIKGAVGR 83   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG  +a ++ +R+ Tl  e + + ++g f+D+R+GE++   +     EeK
  gi|7100558    84 PGAAKASGLAQRRETLLPEWQARDRTGTFVDRRFGENDANMT----PEEK 129  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   MleRf  E+  Q+r +K  a nln   +D+ ++++ g+s     l +l  
  gi|7100558   130 MLERFATEK--QRRAAKGAAFNLN---DDDDLLTHYGQS-----LSGLDD 169  

                   lge.eLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVme
                   l +  L +ddE  d++   + +a ++F++ ++   e ++   KsK+ Vm 
  gi|7100558   170 LADiRLPEDDEDEDDS--GRMTAQGHFGGFGD--NEDGE---KSKADVMR 212  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   E+IaKSK+ K Er+K K+    l++ LD+   d+  ll  e+++     +
  gi|7100558   213 EVIAKSKFHKLERQKVKDADDELREQLDDELADIRGLLF-EQPA-----V 256  

                   Kkpreake.........................dtDae.........YDl
                    +p +++ ++ +++ +  +++ ++ + +   + +tDa  ++++++++YD 
  gi|7100558   257 PTPAPPIDtnakpklsvfpgpatganatavagvNTDATagqdkptssYDT 306  

                   llkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEled
                   +++E+ fe RA+P dR+K eEElA++ ae+Lr+ E  RlkRM+++e + +
  gi|7100558   307 FVRELAFERRAKPQDRLKSEEELAAEQAERLRKAEKARLKRMRGDESDDE 356  

                   gEeE..........iGGEESvkklkvrSvdDLdDsfsVEEDKP..KfGfi
                    +e+++++++++++ G   S +  +   +dDLdD f  +    ++ +G +
  gi|7100558   357 ADEDddggkrrkrsKGANSSSAPKRAAQADDLDDDFELDGMTAgeVYGLG 406  

                   edlle..REDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkd
                    +l e++  D  d+eEdd+ +d+  e+  Dd  +               +
  gi|7100558   407 AGLAEsgTVDASDAEEDDDTEDDNDEEGQDDAAEGV-------------E 443  

                   dEneDDdLGAELEDkeGeeDdEeD.........edEESDaEldvlkdLKe
                    E+eDDd      D e eeDd  D  + ++  + +E  D+E +   +   
  gi|7100558   444 IEEEDDD------DDE-EEDDFADladaddairIGEDEDSEQEGDHEALT 486  

                   deaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheell
                   +++  + + +   +   K   K    T     +  +pFt+ cP th+ell
  gi|7100558   487 SYSKAEAKTGKTDT-VTKP--KSTPVT-----QSKLPFTFSCPATHDELL 528  

                   eLlkkldl..eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                    Ll+ +  +++  p++++RI+++hhp L+e+N K +l  F  vL  h   
  gi|7100558   529 SLLETHQInpKHIPTVIKRIRTLHHPSLAEDN-KYRLQAFIGVLIDHT-- 575  

                   LfEDlseQdikkn........LNfqLLekLveaLielaqelPeklaisls
                   L+   + Q+    ++++++++L f   + L ++ ++l+q  P + a  + 
  gi|7100558   576 LH--WAGQAQMHQsttgqkhkLAFAIVNSLIPHIFSLSQTYPAASAEHFV 623  

                   eellevikelaeeykk.....nEhikyPSlkdLvfFkLvgllFsTSDfrH
                   ++l  +   l     k+++++n    +P l  L +++Lvg  ++TSD+ H
  gi|7100558   624 NKLALMQRNLSRGLAKgptedN-ARTWPGLPELTLLRLVGTVWPTSDKQH 672  

                   lVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVv
                    V TP  ll+a++L   +++S +d a GlfL+s+V      S+R+ Pe  
  gi|7100558   673 NVTTPLALLIAQYLAHARIRSVSDLASGLFLCSLVVSNEVESRRLFPEAL 722  

                   yal..qqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavk
                   ++l ++ +++  ++      ++     t +++R    e G+P   + av 
  gi|7100558   723 NFLfsSIAIL-ASFG----QEKKQQRETLAKIRGVAEEYGIPTPDVDAVH 767  

                   estl......lepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvE
                      l+ +++++   + +  DL    it      + r+ lL++  +l L  
  gi|7100558   768 TRHLrlsgedVVEATDQAVDLPSLIITKSGADSQKRTELLSV--ALTLTS 815  

                   eiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveK
                    ++e y +  ++iE f P++ LLs+  +     ++ ++  l   + l++ 
  gi|7100558   816 KFSELYDGSTSYIELFTPFSVLLSASFS--TASST-VSASLSRSLHLAS- 861  

                   ltedakkerKPLAlqeHKPvaIrllePKFE.EnyDDKRsPdksS.yDpDk
                    t      r  L lq H+ +aI +++PKF + +y    +Pd +S  DpD 
  gi|7100558   862 -TS-----RRYLRLQAHRAIAIASHVPKFDqQGY----NPDRKSaLDPDV 901  

                   eRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmk
                   eR ++ K+ka +K+E+KGAiRElR+D +F+a +R + +a +dq +  Km 
  gi|7100558   902 ERVQIQKMKALIKKERKGAIRELRRDNQFIAQVRKQDQAEEDQTYKRKMD 951  

                   kivnelqeqegAl<-*
                   ki  +lq++  +    
  gi|7100558   952 KIMSTLQVERSEQ    964  

gi|226278062|gb|EEH33628.1|: domain 1 of 1, from 40 to 891: score 485.6, E = 6.9e-143
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKgee
                      +   r +     a i+++fNPF+vk   r+ KF    r         
  gi|2262780    40    NKIQRNAA---LAGIRERFNPFEVKTPSRpaKFSFATR--SNHEAPQ 81   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                     PGV ++ +e++Rk Tl +e   + K g  +D+R+GE+++  +     E
  gi|2262780    82 SRPGVTKGLGEQRRKETLLKEMHRRGKVGTLLDRRFGENDPTMT----PE 127  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   e  +eRf RE   Q +L K +  nl   +ED  e++++g+  + D  D+ 
  gi|2262780   128 ERAVERFARES--QKKLKKESVFNLE-DEEDEIELTHLGQALIFDKEDGD 174  

                   eelgeeLsdddELadeaLDkdflalkrFeeeDAea.......eeeqrGAk
                       ++L   dE  d +    ++     ee+D e+  ++ ++e +++  k
  gi|2262780   175 DFHEDDLNGSDEDGDSE--IARKRRILVEEDDMEGladdledEGPRE-RK 221  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   KsK EVm+E IaKSK+ K Er+K+Ke   Dl+  LD     +  +++m  
  gi|2262780   222 KSKNEVMKELIAKSKFHKYERQKAKEDDDDLRATLDRGLPEI--FEMMRG 269  

                   ltsRKsGiKkpreakedt......................DaeYDlllkE
                   ++      K + e  ++++   + ++++    +++++++ D+eYD  lk 
  gi|2262780   270 VK------KPEPESLPNPdliatmnpdraallngkdrdqaDKEYDQRLKQ 313  

                   MvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMe.eteEledgEe
                   + fekRA+P dRTKTeEE A +EaekL  LE eRl+RM++e  E ++ Ee
  gi|2262780   314 LAFEKRAKPLDRTKTEEERAEEEAEKLKQLEKERLRRMQgENDESSENEE 363  

                   EiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfi.......edlleRED
                                r   D+       +D   fG  ++++ +++++++   
  gi|2262780   364 ---------NASYREMGDESE----RDDAKAFGLAqpssvtdLGVED--- 397  

                   NvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGA
                        Edd  +d+   +sd +   ++                   D+   
  gi|2262780   398 -----EDDFIIDSDLVESDSEADLSL-------------------DE--- 420  

                   ELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplk.......geaik
                      D+    D+Ee ed E            ++   +l+ +++ ++g++  
  gi|2262780   421 --SDIACSADEEESEDKE------------DEFIGSLVlppdaedGKGFA 456  

                   asvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkp
                   ++    A      +T   S + s+++t++cP +he +l+ +    +eD p
  gi|2262780   457 GT---NA----GPST--VSGNQSLAYTYPCPENHEHFLQIIQAAKTEDLP 497  

                   lIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknL
                   +IV+R++ +hhp L+++N K+kl  Fs vL qh    f  l++Q+   + 
  gi|2262780   498 TIVQRVRALHHPRLHGDN-KSKLAAFSKVLVQHT--AF--LANQPNHPP- 541  

                   NfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhiky
                    f  Le L  + +++a++ Pe  a  +++ l+e+          +     
  gi|2262780   542 -FAVLENLLRHIHSMAKSQPEPVATAMRNHLREMSDN------RP----- 579  

                   PSl..kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdI
                   ++l ++dLv +  v+ +F+TSD  H+VvTP++l m  +L +s +    d+
  gi|2262780   580 LELlpGDLVILTGVATIFPTSDHFHAVVTPSMLAMGRYLAQSTITNIGDV 629  

                   aiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPL
                   a G++++++  ++q   kRy+Pe v+ +  ++   l p     + + t +
  gi|2262780   630 ATGAYIATLCIQYQTLAKRYIPEFVNYVLNAIC-ILAP----SEPQTTFG 674  

                   tFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvd
                    F      +      l  +   k s+  ++ +    D+            
  gi|2262780   675 FFPIR--KPTAS---LRIITPSKLSSSAPIRKPAFWDILSDSSADTVEQE 719  

                   alrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrys.....l
                     + SlL+    + L+  + + + + +AF  If P    L  +s++ +++
  gi|2262780   720 TIKLSLLST--FVDLLDQAADLWPSKSAFCDIFSPANRVLKHLSesinnN 767  

                   keslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePK
                     s ++    +++ d+++++ K  +     r PL l +H+P+aI +  PK
  gi|2262780   768 FSSTLSD-QLRRICDKLQALLKQSD---LARRPLLLHKHRPLAIKTAIPK 813  

                   FEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFv
                   FEE +    +P    yDpD+eR+elnKLka +KrE+K A+RElRKDa F+
  gi|2262780   814 FEESF----NPHRH-YDPDRERAELNKLKAEHKRERKWAMRELRKDANFI 858  

                   arlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ar+ l Ek+ kd e+  K +++v+e+q +eg +   
  gi|2262780   859 ARESLREKREKDAEYERKYRRLVAEIQGEEGRE    891  

gi|171687505|ref|XP_001908693.1|: domain 1 of 1, from 38 to 897: score 485.2, E = 8.7e-143
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGr...sKtkvK
                      + e r     A a i+++fNPF  k + r++KF +   ++ s     
  gi|1716875    38    SNEKRIQRHEALASIREQFNPFQFKTNARgpKFEVTTNkpvSSREAM 84   

                   geeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                   g  G PG  +ak+ee+R+ T+  e + +nK g+ iD+R+GE ++  s   
  gi|1716875    85 GISGRPGLTKAKGEERRRETILVEMQRRNKVGGLIDRRFGEDDPNMS--- 131  

                   LeEeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggsSvK
                     E+KM+eR++RE+    r S ++   ++  lED+ee ++++++g     
  gi|1716875   132 -LEDKMIERYTREQ---QR-SHKKHSAFD--LEDDEEmggLTHMGK-PLF 173  

                   DDlDsleelgeeLsdd....dELadeaLDkdflalkrFeeeDA.......
                   D  D    l ++  +d +++dE        d+ alkr + e+A +  +++
  gi|1716875   174 DNDDAPKYLKDDFEEDvgsgDESEGSQ--TDRRALKRQRLEGAleavgeq 221  

                   .eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNf
                   +e++ e++   K+KkE+ eEiIaKSKl K  r+ +Kee   l+ + De +
  gi|1716875   222 eEGQPERK---KTKKEIYEEIIAKSKLHKELRQEAKEEDNELRAEIDEAM 268  

                   kdLlsllamekltsRKsGiKkpreaked...tDaeYDlllkEMvfekRAs
                    dL +ll +  +   Ks   +   a  d+ ++D eYD+ +k M  +kRA+
  gi|1716875   269 RDLRPLLFDRIKPPAKSDKPTLVIAGKDqatLDREYDIQVKRMASDKRAA 318  

                   PsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvk
                   P+d+ KTeEE+A++Ea +L +LEe RlkRM++    +d E      ES  
  gi|1716875   319 PTDKMKTEEEKAAEEANRLKKLEEDRLKRMRGEKV-SDDEQ-----ESDD 362  

                   klkvrSvdDLdDsfsVEEDKPKfGfiedlle.....REDNvdNeEddEd.
                     k ++ dD d+   V ED   fG ++++  + ++ R    + + ddEd+
  gi|1716875   363 ENKQGGDDDFDA-MDV-EDADEFGLGQGIAGkakkyRPTATELGFDDEDd 410  

                   ...ddeeae.......dsdDddsvndGtdlkqkKeavLkddEneDDdLGA
                      dd++ +++++ + dsdD+  ++d             +dE++  d   
  gi|1716875   411 fliDDDLVAsgselefDSDDEGEESD-------------EDEESGSD--- 444  

                   ELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKA
                        + ee+d  D+ +            K    +++ + +i       +
  gi|1716875   445 ---SGS-EEEDSDDDEFT-----------KGLLTESEAKQGIFRL---PT 476  

                   NmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIi
                   N  K +d         +p+t++cP +h+elle  k+ d ++ p   +RI+
  gi|1716875   477 NNTKGSDE------NGVPYTFPCPQNHDELLEIFKGIDVKQLPVATQRIR 520  

                   kahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLek
                    +hhpKL+ +N Ke+l++F  +L +h+   +  l +Q          Le 
  gi|1716875   521 ALHHPKLASDN-KERLGNFAQALVRHV--NY--LGNQYQPTW--AAALEG 563  

                   LveaLielaqelPeklaislseellevikelaeeykknEhikyPSlkdLv
                   L+ + ++la+++P           + +i e+  +   +    ++ ++dL+
  gi|1716875   564 LTRHIHSLAKSFPIE----VAKGYRSIIQEMEQS--RP---LALTVGDLI 604  

                   fFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsi
                    +   g  F+TSD  H VvTPa++ +a +L +   +Sl+d a G fL+ +
  gi|1716875   605 TLTGAGTTFPTSDHFHQVVTPAMIVIARYLGQKIPQSLSDYATGTFLAIL 654  

                   VLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDs
                    L++q  SkRyvPeV+++    L   l p         tP   +      
  gi|1716875   655 ALQYQQFSKRYVPEVMNFTLNTLC-ALAP----SARAFTP-NTIGF---- 694  

                   lekGLPldnlfavkestllepqrLslaDLVtqtiteefpvda....lrsS
                        P    +a +++    p   s a     t +  +p+ +++ +l+ S
  gi|1716875   695 ----FPIHDPPAGTRLPTSLPADASAAR--KLTFSDCLPSNQpsleLKLS 738  

                   lLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlk
                   l     +l+L+  +++ +   ++F E f   l  Ls ++         l+
  gi|1716875   739 LFTT--TLSLLTSASTLWSQTSSFTETFSLALPILSSIPK------S-LS 779  

                   eklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRs
                     + +  + ++ l    +  r PL l  H+P+aIr+  PKFE  +     
  gi|1716875   780 PAIQSLQQHLTRLLQISRLSRRPLELHHHRPLAIRTYIPKFEDSF----D 825  

                   PdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaa
                   P k  yDpD+eR+el+KLk+ +KrE+KGA RElRKD  F+ar+ l  k  
  gi|1716875   826 PNKH-YDPDRERAELAKLKKEHKRERKGALRELRKDNAFMARENLRVKKE 874  

                   kdqerhEKmkkivnelqeqegAl<-*
                   kd ++  K k++v+e+q  eg     
  gi|1716875   875 KDAAYEKKYKRLVAEIQGTEGQA    897  

gi|145253342|ref|XP_001398184.1|: domain 1 of 1, from 37 to 865: score 485.0, E = 1e-142
                   *->keedreeKKKAvakiqkefNPFdvkva.krKFdi....lGrsKtkvK
                      +   r     A + i+ +fNPF++k++++ KFd+++++ G+   k K
  gi|1452533    37    SAQNRMKRESALQAIRDRFNPFEIKATsRPKFDVttrdVGP---KSK 80   

                   geeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                   +    PGV +  +eekR+ Tl  e   knK g+++D+R+GE ++  +   
  gi|1452533    81 HGHARPGVTKSLGEEKRRHTLLREMDRKNKVGGILDRRFGEDDPTMT--- 127  

                   LeEeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggsSvK
                     Ee   eRf RE   Q +L K ++  +n  lED+ee+ ++++ g+s   
  gi|1452533   128 -PEERAAERFARES--QKKLRKESM--FN--LEDDEEefqLTHQGQS--- 167  

                   DDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkK
                          + +e  +d++ L+d+           F +e  e + e++   K
  gi|1452533   168 -------LKREFADDEEALDDDI---------VFDDEEGEEQPERK---K 198  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   sK EVm+E+IaKSK+yKaEr+K+Ke   Dl+++LD+   dL   l   k+
  gi|1452533   199 SKHEVMKEVIAKSKFYKAERQKAKEDDDDLREELDKGLPDLFDMLRGVKP 248  

                   tsRKsGiKkpreakedtDa.............eYDlllkEMvfekRAsPs
                     +    K+ +    + +a    +++++++++eYD  lk + f+kR +P+
  gi|1452533   249 PPKPEPPKDDFASMDPARAallagksqneteqEYDQRLKQLTFDKRSQPT 298  

                   dRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkkl
                   dRTKT EE+A++Eae+L +LEeeR +RM++ e  ed+Ee    E+     
  gi|1452533   299 DRTKTAEEKAAEEAERLKKLEEERVRRMRGEEPSEDEEE----EDEEESD 344  

                   kvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaeds
                     +S dD     s  +D   fG  +     E     e   Ed+d+ + d 
  gi|1452533   345 EEGSEDDDEE--SLPDDAKAFGLQQ--PTAETSTRPELGVEDEDDFIIDD 390  

                   dDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEE
                   d  +  +          a L  dE +D +    +E  e e D+E  +d E
  gi|1452533   391 DLVETRSN---------ASLSFDE-SDLE----MESAE-ESDEEPEDDQE 425  

                   SDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsip
                            +L +    p+ +++   +    A                  
  gi|1452533   426 --------DELINGFTLPESKSGDTST----A------------------ 445  

                   FtidcPktheelleLl.......kkldleDkplIVeRIikahhpKLkeeN
                        P + ee ++  +++ +++   +  D p +V+RI+ +hhp L+++N
  gi|1452533   446 -----PNSTEEPTDAMtsswrssRTVSMQDLPVVVQRIRALHHPRLHPDN 490  

                   RKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqe
                    K kl+ F  +L  h+   +  ++ ++   +  f   e    + ++la+ 
  gi|1452533   491 -KMKLGRFAGILVEHV--AY--MADLPEHPP--FAIVENILRHIHSLAKT 533  

                   lPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsT
                    P        +  +    + a e   n     +  +dLv +  ++  F+T
  gi|1452533   534 HPDT----VCQAYRAHLRQIATERPLN-----LRAGDLVILTGIATTFPT 574  

                   SDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRy
                   SD  H++ TPa l ++ +L +  v+Sl d + G + +s+ L++q iSkRy
  gi|1452533   575 SDHFHAIATPAHLCISRYLGQGVVNSLADASAGTYAASLLLQYQFISKRY 624  

                   vPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlf
                    Pe ++     L   l pK   e l   PL   +    sl +     nl 
  gi|1452533   625 MPEFINYTLNMLC-HLSPKEPSESLGSFPLRSPQT---SLRL-----NLS 665  

                   avkestllepqrLslaDLVtqtiteefpv.dalrsSlLliKEvleLvEei
                     k  t + p +L   D    t    ++ +  l+ SlL     + L+ ++
  gi|1452533   666 SSK--TTISPRKLRFWD----TTDQTHSNpEELKLSLLTT--LVTLLGTA 707  

                   veiyyklqAFiEIflPIlaLLsry.....slkeslpekRlkeklldavel
                   ++ + + +A+ EIf P++  L  ++++ +++k+ + +  +   + +++ +
  gi|1452533   708 SDLWTSKSAYTEIFTPVQNVLNHLrsslkGNKKLISSQ-VRDTIQSTLDK 756  

                   veKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpD
                   v+     ak  r PL l +H+P+aI +  PKFEE +    +Pdk  yDpD
  gi|1452533   757 VTTQLSQAKLTRRPLLLHNHRPLAIKTAIPKFEETF----NPDKH-YDPD 801  

                   keRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKm
                   +eR+e n Lka  KrE+KGA+RElRKDa F+ar++l Ek   d e+  K 
  gi|1452533   802 RERAESNRLKAEYKRERKGAMRELRKDANFIAREKLREKKERDAEYERKY 851  

                   kkivnelqeqegAl<-*
                   k++v+e+q +eg +   
  gi|1452533   852 KRLVAEVQNEEGRE    865  

gi|289621371|emb|CBI52154.1|: domain 1 of 1, from 38 to 893: score 477.9, E = 1.4e-140
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsK....tkv
                      + + r     A a i+++fNPF  k + r++KF +    K++++   
  gi|2896213    38    STDKRLQRHEALASIREQFNPFQFKTSARgpKFEVTTN-KpqndKLA 83   

                   KgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGD
                   Kg  G PG  +a ae++Rk Tl  e + +nK g+++D+R+GE ++  +  
  gi|2896213    84 KGIQGRPGLAKATAEQRRKETLLVEMQRRNKVGGIVDRRFGEDDPNMT-- 131  

                   qLeEeKMleRfsRErmSQlrLSKreaynlnDGlE...Dv...eedGdrgg
                      E+KM+eRf RE+    + S ++   ++  lE+++D+ ++ ++++ g 
  gi|2896213   132 --LEDKMMERFAREQ---MK-SHKKNTVFD--LEgsdDDaeqVTLTHAGK 173  

                   sSvKDDlDsleelgeeLsdd..dELadeaLDkdflalkrFe..eeDAeae
                   +   DD D +e  +++ ++  +d + d++  ++ + lkr + +ee Ae+e
  gi|2896213   174 T-LFDD-DDMEVGRDDFDENisDMESDDERSARKKFLKRLRaeEEAAEGE 221  

                   ....eeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNf
                   ++++++ r  kK+KkEVmeE+IaKSK  K Er+++Kee eDl+ +LD+  
  gi|2896213   222 gedgQPER--KKTKKEVMEEVIAKSKAFKYERQAAKEEDEDLRVELDKEL 269  

                   kdLlsllamekltsRKsGiKkpreak.......edtDaeYDlllkEMvfe
                     ++sll   k++      K+p  + +  + + e + +eY   lk    e
  gi|2896213   270 RQVQSLLFQMKPK----ETKEPKGPAtvagidlEQLEKEYNMRLKQATRE 315  

                   kRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGE
                    RA ++dRTKTeEE A +   +L e Ee Rl+RM++    +d Ee    E
  gi|2896213   316 ARAEVTDRTKTEEERAEEGVKRLKEMEEKRLRRMRGEVV-SDDEE----E 360  

                   ESvkklkvrSvdDL.dDsfsVEEDKPKfGfiedlleREDNvdNeEddEdd
                   E  kk k  + d + +D    E D   fG ++++  R    + + ddEdd
  gi|2896213   361 EEPKKGKKKGDDQEvQD----EADEDEFGLGKGIKLRMTATEMGLDDEDD 406  

                   deeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeG.eeD
                     +  d+    +  +              d +eDD       D eG+ e+
  gi|2896213   407 FLLEDDLIA-SGSEL--------------DMDEDDM-----SDVEGsDEE 436  

                   dEeDedEESDaEldvlkdLKedeaqplkge.aikasvkeKANmKKsadTi
                   d  D dE          +L +  a  + +e a k     KA         
  gi|2896213   437 DAYDPDED---------ELVNGGADGESEEvATKLHAQSKA--------- 468  

                   PASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLke
                       +  ip+t++cP +he ll+ l  l  +  p  V+RI+ ++hpKL e
  gi|2896213   469 --GDEDGIPYTFPCPESHEQLLDILGNLPVAKLPVAVQRIRALYHPKLNE 516  

                   eNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLiela
                    N Ke+l++F+ +L  hI   +      d  ++  f   e L  + ++la
  gi|2896213   517 KN-KERLGNFTQALIEHI--AY----LGDNFEPTWFPAIENLIRHVHSLA 559  

                   qelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllF
                   + +  +    ++e+ + ++ +l e++k      ++ ++dL+++  +g  +
  gi|2896213   560 KTF--F----AIEVSKAYRARL-EQIKEE-RPLALTVGDLMLLTAIGTTY 601  

                   sTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSk
                   +TSD  H VvTPa+l +  +L +   ++l d +iG++L  + L++qs Sk
  gi|2896213   602 PTSDHFHQVVTPAMLSITRYLGQKIPQTLADYSIGAYLSILALQYQSFSK 651  

                   RyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldn
                   RyvPe +++    L  l  + +  e l + P   e              +
  gi|2896213   652 RYVPEFINFCLNTLCSLAAE-KPKEKLGLFP-VHEPA------------A 687  

                   lfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEe
                      vk  +++ + +L   D   q  +  f + +       i  + + + +
  gi|2896213   688 GIRVKGASKVTVRKLNCGD-CQQPKSTRFASEDSAQKVAIISTITSVLRT 736  

                   iveiyyklqAFiEIflPIlaLLsryslk...eslpekRlkeklldavelv
                   ++e + kl+AF E f P +  L+ ++ k++   lp   l + l+d++  +
  gi|2896213   737 ASETWCKLPAFYETFQPAQRVLQHLTTKsnaAQLPAA-LVKQLKDTTTSI 785  

                   eKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDk
                   + l   a+  r PL l  HKP+aI + +PKFE  +     P k  yDpD+
  gi|2896213   786 SRLLQLAQVSRRPLELHHHKPLAIKTYVPKFEDSF----DPNKH-YDPDR 830  

                   eRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmk
                   eR+e++KL+a +K+E+KGA RElRKDa F++r+ lk k akd ++  K k
  gi|2896213   831 ERAEMAKLRAEHKKERKGALRELRKDAAFMQRENLKVKKAKDEAYEKKYK 880  

                   kivnelqeqegAl<-*
                   ++v+e+q  eg     
  gi|2896213   881 RLVAEIQGSEGQA    893  

gi|254573674|ref|XP_002493946.1|: domain 1 of 1, from 40 to 805: score 477.3, E = 2.1e-140
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdil.GrsKtkvKgeeG
                        +dr+     +  i+++fNPF+v+  k KF + +Gr        + 
  gi|2545736    40    RRDDRAQV---ISRIREQFNPFEVRKGKTKFEVSnGR-----SVGVA 78   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                   kP+VS++++e++R+ +    +  +nK g++iD+R+GE++k  +     Ee
  gi|2545736    79 KPSVSKQVGEQQRRAAYDVTKSRRNKVGGVIDRRFGENDKNMT----PEE 124  

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsle
                   KMleRf+REr  Q++ SK ++ynl     D+    + g +        l+
  gi|2545736   125 KMLERFTRER--QSQTSKNSLYNLE----DDDGSDNDGIT--------LT 160  

                   elgeeLsdddELadeaLDkd...flalkrFeeeDAe.aeeeqrGAkKsKk
                   ++g +Ls++d   d + D d+++f+     +  D e+  ++ r  k +K+
  gi|2545736   161 HYGKSLSLGDNNEDNE-DGDgdgFTIVTEKRQLDEEtVDQPSR--KRTKA 207  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll..ameklt
                   EVm E+IaKSK+yK+ r  + e+    i  LD+ f+d+l +l+++    t
  gi|2545736   208 EVMQEVIAKSKFYKQQRKLQHEKDSERIMDLDDEFEDILGELksMQNENT 257  

                   sRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEa
                          +   ++ed  + YD  l+ + ++ RA P+dRTKTeEE+ ++ +
  gi|2545736   258 ------NDSKAPIEDETK-YDETLRALNLDRRAVPADRTKTEEEIVKERE 300  

                   ekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV
                   ek  +LE+ R  RM+++   e   e               +d LdD    
  gi|2545736   301 EKMQKLEQDRQLRMQGMDV-EKTGE---------------GDELDD---- 330  

                   EEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkq
                           f+                 + dee e++ D            
  gi|2545736   331 -------TFWA----------------GSDEEVEELGD------------ 345  

                   kKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKed
                                        D e  +  Ee   E+        ++   +
  gi|2545736   346 -------------------FVDGEKNVPPEEYFEES-------SSEGTTE 369  

                   eaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelle
                     q+ + e + ++   K  +   ++       +  +    cP the +l 
  gi|2545736   370 KIQSTPSESVTITIGNKKVVSQNSSK-----KTHFA----CPETHEQFLH 410  

                   LlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfE
                    l     e +  +++RI  +++p L+e+N Kekl+ Fs v L+h   L+ 
  gi|2545736   411 ILIPYKVEEHLDVIKRILNLYQPRLAEGN-KEKLGVFSTVILGHF--LY- 456  

                   DlseQdikknLNfqLLekLveaLielaqelPeklaislseellevikela
                    l+ +    +      e L+  L e+a +  e l   +++el++   +l 
  gi|2545736   457 -LADLEEPVP--QSVIEGLMVVLREMASKYNEPLTQAFRSELKKLGEKLD 503  

                   eeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsr
                      +         l+dL++F  +g  +sTSD +HlVv P  +l+ evL+ 
  gi|2545736   504 SDNVTV------KLSDLLLFTVIGYVYSTSDMYHLVVNPTVILITEVLET 547  

                   spvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRD
                     +s  +   iG +L+ +  +fqs SkR +PeV  +l+  +   l p  +
  gi|2545736   548 LDISNIQHLLIGTYLADLLYQFQSLSKRIIPEVNRFLERSII-SLCP--E 594  

                   VellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtq
                    e l  t L  +   + +  +     nl  +   ++l  q  +l+     
  gi|2545736   595 PEKLDYTQLYTATSHIKPSGL-----NLQSN---SKLASQEFQLTH---- 632  

                   titeefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLs
                       e +vd+  + lL     l+ v  +  i++  ++F EI +P+ + Ls
  gi|2545736   633 --FHEASVDDTPA-LLEK--LLQIVDKFTLIWKEKSSFVEISVPFIT-LS 676  

                   ryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrl
                   + s k+    k l   ll ++  + K      ke+ PL lq H+ ++I +
  gi|2545736   677 KHSVKYYASDK-LVVDLLGKLNQLYKVNI---KEHRPLKLQAHRAISIMT 722  

                   lePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKD
                     PKFEEn+    +Pdk+SyDp + R elnKL+ + K+E+K + +ElRKD
  gi|2545736   723 NTPKFEENF----NPDKKSYDPNRDRQELNKLRSQFKKERKLTLKELRKD 768  

                   akFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ++F ar+ +kEk ++  e+h+ m+ i+n ++++egA    
  gi|2545736   769 TRFTAREQIKEKKKQQEEYHARMAYIYNSISTEEGAD    805  

gi|116180704|ref|XP_001220201.1|: domain 1 of 1, from 38 to 897: score 473.9, E = 2.3e-139
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdilGrsKtkvKge.
                       ++ r     A a i+++fNPF  k + r++KF +       +K + 
  gi|1161807    38    RPDKRLQRGEALASIREQFNPFQFKTNARgpKFEVTTNKPANDKATm 84   

                   ..eGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDq
                   + +G PG  +a++ee+R++Tl  e + +nK g+ iD+R+GE ++  s   
  gi|1161807    85 siKGRPGLAKAVGEERRRQTLLVEMQRRNKVGGLIDRRFGEDDPNMS--- 131  

                   LeEeKMleRfsRErmSQlrLSKreaynlnDGlEDve...edGdrg.....
                     EeKM+eRf+RE+  Q+    ++   ++  +ED+e+ + ++++g++  +
  gi|1161807   132 -LEEKMMERFTREQ--QRN--HKKSSMFD-LEEDDEpmgGLTHMGrplfd 175  

                   ....gsSvKDDlDsleelgeeLsdddELadeaLDkdfl........alkr
                   +++++  vKDD+D+     e+L  +dE ++    ++++ +++++ +a   
  gi|1161807   176 ddedQVPVKDDFDE-----EDLASGDESDNSR-AERRMlkrqrraeAGEE 219  

                   FeeeDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidk
                    eeeD+  + e++   K+KkE+ eEiI KSK  + Er+++K+e   l+ +
  gi|1161807   220 QEEEDDDDQPERK---KTKKEIYEEIISKSKQHRYERQAAKDEDSELRAE 266  

                   LDeNfkdLlsllamekltsRKsGiKkprea....kedtDaeYDlllkEMv
                   LD  +  ++ ll   ++   K G    +++ +++k+ +D+ YDl ++ + 
  gi|1161807   267 LDQTMPEIQALLFQRQKPPAKDG--PSMVIagkdKSALDKDYDLRIRLLA 314  

                   fekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee..teEledgEeE
                    +kRA+P++RTKTeEE A +E  +L eLEe RlkRM+++    +ed Ee 
  gi|1161807   315 ADKRAQPAERTKTEEETAEEESKRLKELEERRLKRMRGevVSDDEDDEE- 363  

                   iGGEESvkklkvrSvdDLdDsfs...VEEDKPKfGfiedlleREDNvdNe
                           k k + + D+d+ +++ + E+D   +G + ++  R    + +
  gi|1161807   364 --------KGKRGKANDEDA-DNpfdAEDDDDEYGLGAGVKYRPTAAELG 404  

                   EddEd....ddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAE
                    ddEd+   dd++ +     + ++d             +dE +DD+    
  gi|1161807   405 FDDEDdfliDDDLVASGSELELESD------------MEDEGSDDE---- 438  

                   LEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKAN
                     D     + + D+dE       v   L e   +  k     +s   K  
  gi|1161807   439 --DAG--SESGSDDDEF------VKGILTE---AVTKDPVFQISSNTKG- 474  

                   mKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIik
                        d      +  ip+t++cP th e+l+   +      p  V+RI+ 
  gi|1161807   475 -----DD-----EDGIPYTFPCPQTHAEMLQAFDGIEVSKLPVAVQRIRA 514  

                   ahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekL
                   ++hpKL   N Ke+l++Fs +L qh+   +      d  ++  f  Le L
  gi|1161807   515 LYHPKLDSKN-KERLGNFSQALVQHV--AY----LGDNFEPQWFPTLENL 557  

                   veaLielaqelPeklaislseellevikelaeeykknEhikyPSlkdLvf
                     + ++la+++P         + + ++   +e +  n    ++ ++dLv+
  gi|1161807   558 SRHIHSLAKSFPIE-------VAKAYRAHIQE-IEQN-RPLALTVGDLVL 598  

                   FkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiV
                   +  vg  F+TSD  H VvTP++l +a +L +   + l+d a G +L  + 
  gi|1161807   599 LTAVGTTFPTSDHFHQVVTPSMLAIARYLGQKIPQALSDYATGTYLSILA 648  

                   LkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDsl
                   L++q  SkRyvPe++++    L  l  + +  + l   P     d     
  gi|1161807   649 LQYQQFSKRYVPELMNFCLNTLCSLAHE-KTRKSLGFFP---VHD----- 689  

                   ekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliK
                          +   +k  ++  + +L   D   +  + +     l+  l +  
  gi|1161807   690 -----PAAGTRIKGASKTTIRQLNCGDCQPKQSLSAAEEASLKVALIST- 733  

                   EvleLvEeiveiyyklqAFiEIflPIlaLLsryslk...eslpekRlkek
                    +   + ++ e + kl+AF E f P l  L+ +++k++   lp   l  k
  gi|1161807   734 -TTAILKTAAETWHKLPAFHETFHPALLVLQHLTSKptaTYLPPA-LLTK 781  

                   lldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPd
                   + d++  ++ l   a+  r PL l  H+P+aIr+  PKFE  +     P 
  gi|1161807   782 ITDTTTTLTRLLQLARLSRRPLELHHHRPLAIRSYIPKFEDAF----DPN 827  

                   ksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakd
                   k  yDpD+ R+el+KL+a +KrE+KGA RElRKDa F++r+ l  k   d
  gi|1161807   828 KH-YDPDRDRAELAKLRAEHKRERKGALRELRKDAAFMQRENLRVKKERD 876  

                   qerhEKmkkivnelqeqegAl<-*
                    ++  K k++v+e+q +eg     
  gi|1161807   877 AAYEKKYKRLVAEIQGEEGKA    897  

gi|50555500|ref|XP_505158.1|: domain 1 of 1, from 34 to 817: score 471.1, E = 1.6e-138
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +   r+   K    i+++fNPFdvkva++K di+Gr    v+g +G 
  gi|5055550    34    SGKNRQDRDKVLSDIRQQFNPFDVKVARKKHDIGGR---TVRGSVGR 77   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG S+  +ee R  +   e++ k + g++ D+R+GE +         EeK
  gi|5055550    78 PGLSKLSGEEARMEARKLELQNKGRVGGVFDRRFGEGDSNMN----PEEK 123  

                   MleRfsRErmSQlrLS.....KreaynlnDGlEDveedGdrggsS.....
                   MleRf+REr  Qlr S +++++++   l+   +D+  d d+ ++ +++  
  gi|5055550   124 MLERFTRER--QLR-SmgggrNKSIFALD--DDDDDADADMMLTHsgqal 168  

                   .vKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDA........
                   + KDD+D +  lg e  +d+E a     + +  l+  ++ +A + + ++ 
  gi|5055550   169 dFKDDFDQG-DLGIEAEEDEEMAAIL--ANRRKLAEERGMGAmgvnleem 215  

                   ...eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDe
                   ++   ee + G kKsK EVm+EiIaKSK+ KaEr++++++    i++  +
  gi|5055550   216 dgvDMEEAGTGRKKSKEEVMKEIIAKSKFHKAERQAARDKDQAIIEEMND 265  

                   N..fkdLlsllamekltsRKsGiKkpreakedtDaeYDlllkEMvfekRA
                    +++  L+ +l   + +      Kk   a     +eYD   + M+++ RA
  gi|5055550   266 EdtMNALIRELG--SIK-----AKKVVTALDQKEKEYDQNFRNMILDRRA 308  

                   sPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESv
                   +P dRTKT EElA++EaekL +LE+eR  RM++      gE         
  gi|5055550   309 KPQDRTKTDEELAKEEAEKLKKLEDERQARMRGEVAIDQGEG-------- 350  

                   kklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeea
                           dDLd   +V      f f             eE+ Edd +ea
  gi|5055550   351 --------DDLDG--NV-----AFDFEN----------SEEEGEDDEDEA 375  

                   edsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDe
                   ed dD+d +                 E + D+      D++  +  +  +
  gi|5055550   376 EDDDDEDVEIH---------------EVDEDE------DES-GDKSGDES 403  

                   dEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdr
                   +EE                +  k e  + s         s++T       
  gi|5055550   404 GEE----------------ETTKSEPASKS---------SSST------- 421  

                   sipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKek
                    +++t++ Pk+h  +le  +   l++ p+I+ RI  +hh  Lke+N Ke+
  gi|5055550   422 -LAYTFPIPKSHKMFLETTSAYPLDQLPTIIDRINVLHHASLKEGN-KER 469  

                   lvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPek
                   l KF  vL  h+  ++  l+         f+ L+  v   + la   +  
  gi|5055550   470 LAKFACVLIDHL--MY--LADEEEEDD--FECLSEVVAKVHTLAETHSPT 513  

                   laislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfr
                       +   +++     ++             + L++  L+g +FsTSD  
  gi|5055550   514 ----MAAHIRKKLEAHQADTTVT-------AGHLMLWTLIGMIFSTSDHF 552  

                   HlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   HlVvTPa l m  +Ls s ++S      Gl+ + +  ++q+i kR++Pe+
  gi|5055550   553 HLVVTPAVLVMTRFLSLSTFDSIPKCIAGLYTAQLLIQYQRIAKRFIPEI 602  

                   vyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavke
                     +l   +     +              e          LP   lf + +
  gi|5055550   603 AVFLGRLIA--ALE------------GTETS--------LPMASLFKIAP 630  

                   stllepqrLsl..aDLVtqtiteefpvdalrsSlLliKEvleL.vEeive
                   +    p + s +++D   +ti    + +    S+L+ KEv  L+ E +  
  gi|5055550   631 IKGFTPGKASHksTD---KTI----SMRSANRSILSKKEVATLsQELHNQ 673  

                   iyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKlted
                   + ++ +         ++    +s   + +e    e++   + + +  t  
  gi|5055550   674 AVFSVS-------KLMDTYKDISAFPETFEF--CENIPELADKYSRITKF 714  

                   akkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRseln
                     + rKPL l +H+P+aI + +PKFEEn+    + dk+Sy pD +  e  
  gi|5055550   715 KLADRKPLTLHKHRPLAIKTMAPKFEENF----NVDKKSYNPDMALQETQ 760  

                   KLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnel
                   KL+a lK+EkK A RE+RKDa F+ar+++ E++ kd ++hEKm+++v  +
  gi|5055550   761 KLRAELKKEKKSALREIRKDAAFEAREKIRERREKDDAYHEKMARLVRSV 810  

                   qeqegAl<-*
                   q++egA+   
  gi|5055550   811 QTEEGAE    817  

gi|256732640|gb|EEU45988.1|: domain 1 of 1, from 34 to 890: score 462.4, E = 6.4e-136
                   *->keedreeKK....KAvakiqkefNPFdvkvakr.KFdilGrsKtkvK
                       e +r eK+ +++     i+++fNPFd k ak +KF +      + K
  gi|2567326    34    DERARNEKRlqrgVVLEGIREQFNPFDLKHAKGpKFEVTTN---RPK 77   

                   g......eeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnk
                    ++  ++ +G PG  +a  ee+R+ Tl  e + +nK g+++D+R+GE+++
  gi|2567326    78 ApgiagsIKGRPGQAKAASEERRRETLLVEMQRRNKVGGILDRRFGENDP 127  

                   hLsGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDv...eedGdr
                           EeKMleRf RE+    r S ++   ++  lED++++e ++++
  gi|2567326   128 TMA----PEEKMLERFAREK---QR-SHKKSSMFD--LEDDepeESLTHM 167  

                   ggsSvKDDlDsleelgeeLsdddELadeaLDkdf.......lalkrFeee
                   g s   DD+  +e   e+  d+d   d ++ ++ + ++ +++a+ +  +e
  gi|2567326   168 GKSLSFDDMKRVEDFQEDDLDEDYDSDGSVRERQrlkrlrdMAATGSDGE 217  

                   DAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeN
                   D e+ e+ r  kK+KkEVmeE+IaKSKl K Er+++K+   Dl+ +LD+ 
  gi|2567326   218 DGENDEPER--KKTKKEVMEEVIAKSKLHKYERQAAKDQDDDLRAELDKE 265  

                   fkdLlsllamekltsRKsGiKkpreake....dtD...aeYDlllkEMvf
                      L  ll+  +      G K +    +  + d D+ ++  Dl +k +  
  gi|2567326   266 LPNLHALLS--QGR---QGTKAQAAVSTiagvDRDtfeKNFDLQVKKLAQ 310  

                   ekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGG
                   +kRA+P+dRTKT EE+A +E  +L eLE+ R +RM++ eE +d+E     
  gi|2567326   311 DKRAQPADRTKTDEEKAEEESKRLKELEDKRQRRMRG-EEVSDSED---- 355  

                   EESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEd.
                   +E  k+ k     D+ D    +ED   fG ++++  R    + + ddEd+
  gi|2567326   356 DEADKRKKNQ--QDEMD---LDEDDEDFGLGDGIRARPTATELGFDDEDd 400  

                   ...ddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeG
                      dd++ +   D + v +              dE++D +      D+e 
  gi|2567326   401 fiiDDDLVASGSDLELVDS--------------DEDSDME----GSDEE- 431  

                   eeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsad
                     D+EeD+ +           L e+e    + ea + +   KA      +
  gi|2567326   432 -ADEEEDDEFT-------KGLLNEEERRNPVFEADSTT---KA------S 464  

                   TiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKL
                    i    +  +p+t++cP + +e+   +     +  p+IV+RI+ ++hpKL
  gi|2567326   465 AIEKGDEQGLPYTFECPQSCDEFRVIIAPYPAKTFPTIVQRIRALYHPKL 514  

                   keeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLie
                      N Kekl +Fs +L  ++      l   +  ++  f  Le  v + ++
  gi|2567326   515 SNKN-KEKLANFSTALVDYV---A--LPWDPATSP-PFAVLESIVRHIHS 557  

                   laqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgl
                   la+ +P       s++ +  i e+ e+   +    ++  +dL+++  vg+
  gi|2567326   558 LAKMFPVE----ISQQFRQNIEEMGES--RP---LALGPGDLILLTAVGS 598  

                   lFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsi
                   +F+TSD  H VvTPall++  +L +   + l+  aiG +L  +   +q  
  gi|2567326   599 IFPTSDHFHQVVTPALLTIGRYLGQRVPQNLSHYAIGTYLSILAVSYQKL 648  

                   SkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPl
                   SkRyvPeVv++    L   l p    ++l   PL       +   +    
  gi|2567326   649 SKRYVPEVVNFSLNTLS-ALAPVAASKQLGNFPLHNVPA--GIRTE---G 692  

                   dnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLv
                       av ++++     + +         e+    a +  +L    + +L+
  gi|2567326   693 AGKTAVRRLNFSDCIDEETGG------KEA---AARKVAILDT--TAQLL 731  

                   EeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelve
                   E + + + + +AF E f  + a L  + + +   ++ l+  l   ve++ 
  gi|2567326   732 EAAADTWTGKSAFLETFGQVAAVLKHLNS-KGCRSR-LPPALTERVEKIQ 779  

                   Klted....akkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyD
                    + e   + a+  r  L l  HKP+aI + +PKFEE +     Pdk  yD
  gi|2567326   780 AKFERmlkvAQLSRRNLELHHHKPLAIKTYVPKFEETF----DPDKH-YD 824  

                   pDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhE
                   pD+eR+el+KLk+ +K+E+KGA+RElRKDa F+ar++l  k akd ++  
  gi|2567326   825 PDRERAELAKLKKEHKKERKGAMRELRKDANFMAREKLRIKKAKDEAYEK 874  

                   KmkkivnelqeqegAl<-*
                   K k++v+e+q +eg +   
  gi|2567326   875 KYKRLVAEIQSEEGRE    890  

gi|170047157|ref|XP_001851100.1|: domain 1 of 1, from 8 to 831: score 450.7, E = 2.2e-132
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++++   K K  + ++k  NPF+++ +k KF +l r  t      G 
  gi|1700471     8    SSDALLKK-KSLQGVKKP-NPFEIQTSKTKFNVLNR-DTQTNRQTGL 51   

                   PGVSRakaeekRkrTleaefkkknKsgafiD.kRiGErnkhLsGDqLeEe
                    GV Ra+a+ekRk+Tl++e+ +k+Ks++f+D++R G            Ee
  gi|1700471    52 SGVQRARAIEKRKQTLGQEYLQKHKSNRFVDqRRDG---RNMN----REE 94   

                   KMleR.fsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                    M eR++ + r    r   +e ynln    D   +++rg++     l+++
  gi|1700471    95 LMAERkSGASR----R---KEIYNLN----DSVKLTHRGQT-----LEEI 128  

                   eelgeeLsdddELade..aLDkdflalkrFeeeD.AeaeeeqrGAkKsKk
                   e  ++  + d    de++ LD  f+ +++F++ D++ + +++        
  gi|1700471   129 ERFDDAVDNDIDSEDEggQLDDEFTEAAHFGGGDtDNGRDRKT------- 171  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                    V+eE+Ia+SK+ KaE++ e +ev   + kLD+N  +L   +        
  gi|1700471   172 -VIEEMIAESKRKKAEKQRENDEVFEMTQKLDKNWQSLAAVVG--GHM-- 216  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                        k     + +D+ YD+  +EM+fe R++P+d++K  EElA++E ek
  gi|1700471   217 -----KGDSERPKLDD-YDKVMREMIFERRGKPADKLKSAEELAKIELEK 260  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                    + LE eRl RM + e      +         k k+rS+dDLdD + V  
  gi|1700471   261 QERLERERLARMAGVEN----GA---------KAKHRSADDLDDGYFV-- 295  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                    +P  G  +++       +N+Ed    d      + +++  d        
  gi|1700471   296 -QPAVGSSDGVDV---DRENGEDSSAYDPRNITKEAENGHDD-------- 333  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKe..d
                        +d  e D+ G + ED e e  d e  d        +l+dL e++d
  gi|1700471   334 ----AEDQAEEDESGSDSEDSE-EGSDDEAADKD------NLSDLVEdsD 372  

                   eaqplkgeaikasvkeKANmKKsadTiPASLdr.....sipFtidcPkth
                   e +p  +e  +   +e  N +  a       +r++    +p  +++Pk++
  gi|1700471   373 EDEPVDKEVNSSKASEEQNRRYLAQQ----KEReqaaaEVPLVFEMPKSY 418  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   eel  Ll   +    +++ eRI   +       N K+++  + ++  q++
  gi|1700471   419 EELSSLLNRYSPIKRAIVFERILSSNNGRAVHLN-KSRMISLFAFAVQYL 467  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                    D f  +s ++      f+  + L++ L+ la+ +P   a ++  +++  
  gi|1700471   468 NDCF--ASTLPATVSEAFETVSGLTPFLYDLAKMNPRETATCFQDVVR-- 513  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                     e++ee++k     yP l++Lvf+kLv llFs SDfrH+Vv+Pal +++
  gi|1700471   514 --EKQEEFRKR-PRQYPPLDTLVFLKLVPLLFSASDFRHPVVSPALVFLS 560  

                   evLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   e Lsr+ v+ +kdI  G fLv++ L+   +S R +P+  ++l + ++ + 
  gi|1700471   561 EILSRCQVRDRKDITAGMFLVTVALECTEQSDRILPAALNFLNGVIY-MC 609  

                   vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsla
                    + + +    i+P +F      + +  L l+   +  e t+l +  +   
  gi|1700471   610 AETKAIQVVKIVP-PFKSF--APWSNLLVLEETVEDVEETKLSLRAED-- 654  

                   DLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPI
                     Vt  i   f+ + l + l  i+ v + +    ++             +
  gi|1700471   655 -FVTGAIDDSFKMRVLNTTLGMIRAVCSKLSKLDGAHHIVA-------NF 696  

                   laLLsryslkeslpekRlkeklldavelveKltedakkerKPL....Alq
                   l  L r+   e +p   l+  l d+ +++  l +      KPL+   A+ 
  gi|1700471   697 LPHLRRIDE-ELYPKV-LQTALADTRQALQTLHD------KPLhylvAP- 737  

                   eHKPvaIrllePKFEEnyDD.KRsPdksSyDpDkeRselnKLkaklKrEk
                   e+KP+ +rllePK E+ y+D +R+P+       + R+++ KL  k K+E 
  gi|1700471   738 EKKPKPLRLLEPKIEATYEDiRRRPKNQ---TLPLREQRRKLQQKVKKET 784  

                   KGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   + A RE+R D  F a  Rl ++ a d er EK+k+i  e+  q+g+l   
  gi|1700471   785 RAAAREIRQDNEFLAKMRLHQRVAGDRERREKVKRIFSEATAQQGEL    831  

gi|260948394|ref|XP_002618494.1|: domain 1 of 1, from 36 to 783: score 434.3, E = 1.9e-127
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdi....lGrsKtkvK.
                         d e KK+ +  i+ +fN Fd +v++ K d +  ++G+    vK 
  gi|2609483    36    TRKDTEQKKQEISRIRDDFNQFDNRVNRAKHDYtviqGGK---FVKa 79   

                   geeGkPGVSRak.aeekRkrTleaef....kkknKsgafiDkRiGErnkh
                   g +    V R k+++ek   Tle e++  +k k + g+ +D+R+GE++ h
  gi|2609483    80 GSKQHNQVARSKsGVEK---TLESEYsalqKTKGRAGGLVDRRFGEKDRH 126  

                   LsGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsS
                   L+    eEeKMleRf+REr  Q+  SKr+   l   + D+e   d +   
  gi|2609483   127 LT----EEEKMLERFTRER--QSS-SKRNVFSLE--ESDDEYEDDGFA-- 165  

                   vKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGA
                          l+++g e   d  + ++       a+ ++ +eD + + +++  
  gi|2609483   166 -------LTHSGKEINFDHFEESDL----GVAAPKYVDED-SIQPPRK-- 201  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                    K+KkEVm E+IaKSK+ +  r+ e  +  D+i  LDe f d+l ++   
  gi|2609483   202 -KTKKEVMAEVIAKSKFHRKKRQMEFQKTQDEILDLDEDFADVLGEIRSS 250  

                   kltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAq
                   k++  +sGi    ++k+  D eYD +++E+  e RA P++RTKT EE+A+
  gi|2609483   251 KPA--QSGI----VPKSAEDREYDAKVRELTYERRAVPAERTKTAEEIAA 294  

                   kEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDs
                   + +ek  +LE  RlkRM + eE  + E+                dDLdD 
  gi|2609483   295 EHKEKMQKLEADRLKRMSGFEE-GAAEA----------------DDLDD- 326  

                   fsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                              f+            + d E + ++ ed+ +d+s n    
  gi|2609483   327 -----------FWA-----------GSDEEEEGSGGEDENGDESGNE--- 351  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                                               e DdE  +d E           
  gi|2609483   352 --------------------------N-ENDDE--SDNE----------- 361  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                            g  + as    A                      +P th  
  gi|2609483   362 ---------GRKLLASRRARA-------------------AVSMPETHSQ 383  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   ll++l+  + e ++  +e I  a+hp L+e+N K k+  F   L  hI  
  gi|2609483   384 LLDQLSSVAPEKVISHIEAIAQAYHPRLAEGN-KDKMDAFVGLLFEHI-- 430  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                   L+  l++Q         L + L+ +L  +aq+   +    l e+++e   
  gi|2609483   431 LY--LANQKETP---ASLVSELTQYLRKMAQQYNQA----LVETVREQLE 471  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                        ++       ++ +dLvfF   g  Fs SD  HlV+TPalllm ++
  gi|2609483   472 SVEDHIVSR----QLEKSDLVFFVVLGYVFSASDHFHLVITPALLLMNQF 517  

                   Lsrs..pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   Ls + +  ++ +    GlfL+ + L +q  SkRy+Pe+v +++   +  l
  gi|2609483   518 LSSCigAENTPQHLGQGLFLCDLLLSYQFFSKRYIPEIVKFVEFTSL-AL 566  

                   vpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsla
                   vp    +  + +     +    sl++  P+   ++v     l++q L   
  gi|2609483   567 VP-EPLKVGQTVSCRATKS---SLSL--PKSFRPEVLQDEPLKVQSLF-- 608  

                   DLVtqtiteefpvdalrsS.lLliKEvleLvEeiveiyyklqAFiEIflP
                   +           vd+  s + Ll   ++      v  +   ++ iEI   
  gi|2609483   609 E----------AVDDESSFkFLLLGKAVAIMDRCVSTWMDKSSLIEIVES 648  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                   +  LL  +   +   e     kl +++   +      ++ rKPL lqeH+
  gi|2609483   649 FGHLLKHMAK-YYSVEL---PKLASTLTRFSNIERNQRQSRKPLRLQEHR 694  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                    +aI + +PKFEEn+    +Pdk+SyD  +eR e nK+ka+lK+EkK  +
  gi|2609483   695 QLAIQTYAPKFEENF----NPDKKSYDLNRERQEVNKMKAQLKKEKKSVM 740  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   + lRK ++Fvar+ + Ek +   e+h Km+ ivn +++ egA+   
  gi|2609483   741 KDLRKQTRFVARQQISEKKKMYGEYHRKMANIVNSISTVEGAE    783  

gi|150866880|ref|XP_001386622.2|: domain 1 of 1, from 35 to 809: score 426.1, E = 5.5e-125
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdi....lGrsKtkvK.
                      +e+ r  K + +  i+ +fN Fd + ++ K d++  ++G+    vK 
  gi|1508668    35    SETRRNDKEQVIGDIRTQFNQFDQRINRTKHDVsiiqGGK---FVKl 78   

                   geeGkPGVSRakaeekRkrTleaefkkk..nKsgafiDkRiGErnkhLsG
                   g +      R+    +    l  e++kk++ K+g+ +D+R+GE+nkhLs 
  gi|1508668    79 GSKQHNEAVRTHSTVQKTMKLQYELEKKghGKTGGLVDRRFGENNKHLS- 127  

                   DqLeEeKMleRfsRErmSQlrLSKr.eaynln.DGlEDveedGdrggsSv
                       EeKMleRf+REr  Q   SKr+++    +D  +D+ e G   ++  
  gi|1508668   128 ---AEEKMLERFTRER--QAS-SKRgNMFSIEsDDDNDDFEAGGFTLT-- 169  

                   KDDlDsleelgeeLsdddELadeaLDkdflalk.rFeeeDAeaeeeqrGA
                        ++  l  +  d+  L de+    + a k+r+ +eD   ee q   
  gi|1508668   170 ----HGGRALTLGDGDEAALSDEE--TSLGAGKtRYVDEDQMEEEGQPAR 213  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlslla.m
                   kK+KkEVm+E+IaKSK+yK  r+ e  +  D i+ LDe f d++ +  + 
  gi|1508668   214 KKTKKEVMKEVIAKSKFYKHQRQTEFKKTQDDIEDLDEDFGDVMQEMYnV 263  

                   ekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElA
                    ++t+ K   K++ e+     + YD +++E+  + R  P+dRTKT EEl 
  gi|1508668   264 KQPTAPKFSTKTQEEI-----D-YDNKVRELTYDRRSVPADRTKTDEELK 307  

                   qkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdD
                   ++ +ek  +LE  Rl+RM +     d ++               +dDLdD
  gi|1508668   308 KEHEEKMKKLEADRLRRMTGFVD-DDRDA--------------EGDDLDD 342  

                   sfsVEEDKPKfGfiedlleREDNvdNeEd.dEdddeeaedsdDddsvndG
                               f+ +  e      N Ed++    + ae+s     +n+ 
  gi|1508668   343 -----------DFWAGSDE------NDEDgFAIKESDAEESNE---ENS- 371  

                   tdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlk
                                               +Gee++   + +          
  gi|1508668   372 ---------------------------SSGEEEEATTKNFG--------- 385  

                   dLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                            l+ + +  s                            P +h
  gi|1508668   386 -------RTLPVKKPQVS---------------------------IPSNH 401  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                    e++  l     +  p  V++I   + p L+e+N K k+  F  +L  h+
  gi|1508668   402 QEFVKALVEIEADRQPAYVKKIVEVYKPNLAEGN-KDKMNIFVGILFEHL 450  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                     Lf  ls+Qd          + L e L  + + l+e ++  l e ++e 
  gi|1508668   451 --LF--LSNQDEPN-------SILIEQLADIIKRLSESYNQVLVENVREE 489  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                   i+  + ++        +   dLvfF Lvg lFsTSD +Hl+vTP  +lm 
  gi|1508668   490 INNIQDRIADS----SLLKRDLVFFVLVGFLFSTSDHYHLIVTPTVILMN 535  

                   evLsrspvs...SlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLf
                   e Ls    s++ +   I+ G f + i L +q++SkR+vPe+v++lq++L+
  gi|1508668   536 EILSTLVYSdeaTINQISQGVFTADILLTYQRYSKRFVPEIVNFLQKALL 585  

                   tllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrL
                    ll+p          P   ++d  +s         +f +  +++ +  + 
  gi|1508668   586 -LLIP---------EPTKIAQDVRGSIFS---TSTIF-NSKLNISKSEKF 621  

                   slaDLVtqtiteefpvd...alrsSlLliKEvleLvEeiveiyyklqAFi
                   s+ +     i+  f  d++++++  lL+   ++ L+      ++  +A i
  gi|1508668   622 STLESTEMSISQLFAGDessQFKFQLLNK--IIALIDKSTSLWKEKSALI 669  

                   EIflPIlaLLs...ryslkeslpekRlkeklldavelveKltedakkerK
                   E+   +   L +  +y    slp++    +ll+++ ++        kerK
  gi|1508668   670 EVVESFIVILKhavKYFA-TSLPQT---TNLLNKLVKIQNNLL---KERK 712  

                   PLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkakl
                   PLAlq H+ +aI + +PKFEEn+    +Pdk+SyD  +eR e+nK   +l
  gi|1508668   713 PLALQHHRALAIATFAPKFEENF----NPDKKSYDVNRERQEMNKIQNQL 758  

                   KrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegA
                   K+E+K A + +R  ++Fva + ++Ek     ++h Km++ivn +++ egA
  gi|1508668   759 KKERKAALKDIRQESRFVAGQQIEEKKSMYDAYHKKMAHIVNSISTIEGA 808  

                   l<-*
                   +   
  gi|1508668   809 E    809  

gi|261356226|gb|EEY18654.1|: domain 1 of 1, from 39 to 879: score 425.3, E = 9.8e-125
                   *->keedreeKKKAvakiqkefNPFdvkvakr..KFdi......lGrsKt
                      k + r     A   i+++fNPFd k + r++KF +++++++ G    
  gi|2613562    39    KNDKRLNRTEALNQIREQFNPFDLKHNARgpKFEVttnrpsTGN--- 82   

                   kvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLs
                   + Kg  G P  S + ae++R+ Tl  e + +nK g+++D+R+GE ++   
  gi|2613562    83 AAKGIAGRPVASTTAAEQRRRDTLLLEMQRRNKVGGILDRRFGESDPNMA 132  

                   GDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdr..ggsS
                       eEeKMleRf RE+    r S ++ ++++  lE  e +G++++gg +
  gi|2613562   133 ----EEEKMLERFAREK---QR-SHKKTNLFD--LEEAEPLGELthGGEA 172  

                   vKDD...lDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeae...
                      D++  D + e + + +dd+ La +   k+ l   r  e+D e+e+++
  gi|2613562   173 LTLDtqlVDDFDEDDLDSDDDEGLAEAR--KRALKRIRDAEVDEEGEgge 220  

                   .eeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdL
                   +e+ r  kKsKkEVmeE+IaKSK yK Er+ +K+e e l+  LD+    L
  gi|2613562   221 gEPER--KKSKKEVMEEVIAKSKAYKYERQVAKDEDEELRGQLDKELPEL 268  

                   lsllamekltsRKsGiKkprea.......kedtDaeYDlllkEMvfekRA
                   + lla      RK   K+  +++   + +k   D+  D  lk ++++kR 
  gi|2613562   269 QMLLA---ARVRKNVPKDDKPPqlvagmeKAAFDKDFDRRLKQLILDKRS 315  

                   sPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESv
                   +P++RTKT EE+A +E ekL +LE  R kRM++    +d +         
  gi|2613562   316 KPTERTKTDEEKAEEEVEKLKKLESDRQKRMRGESV-SDDDN-------- 356  

                   kklkvrSvdDLdDsfsVEE..DKPKfGfiedlleREDNvdNeEddEddde
                         S dD       EE+ + P f f+          +  E+d +   
  gi|2613562   357 -----ESEDDKME----EEpaEEPAFQFFT---------EDPEEDFGLGK 388  

                   eaedsdDddsvndGtdlkqkKea.vLkddEne...DDdLGA.........
                   +   s +     +    k++  a+ L +dE++   DDdL A++++ +  +
  gi|2613562   389 GVQASKG----RS----KGRPSAdELGGDEDDffiDDDLVAsgsdldiae 430  

                   .ELE.......DkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeai
                   ++LE++++ ++D+  ee dE D+ +            K    +++  ++i
  gi|2613562   431 sDLEeetdlsgDEQ-EEADESDDEFT-----------KGLLNESETRSNI 468  

                   kasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDk
                     +    A  K  a+         +p+t++cP t  +++ L k    +  
  gi|2613562   469 FTT-GAPADGKVDASD--------LPYTFPCPETVSDFVVLAKQYPIDKL 509  

                   plIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikkn
                   p+IV+RI+  +hpKL     Kekl+ F  +L  +I      +       +
  gi|2613562   510 PTIVQRIRAVYHPKLDSRH-KEKLEHFAIALVDYI---A--MDHIELGTP 553  

                   LNfqLLekLveaLielaqelPeklaislseellevikelaeeykknEhik
                     fq  e  + + ++la+ +      +   + +  ike+  +   +    
  gi|2613562   554 --FQVIEQIMRHIHSLAKTFFPV---EIAVRFRHHIKEMEDQ--RP---Q 593  

                   yPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIa
                   ++  +dL++F  vg +F+TSD  H VvTP +l++  +Ls     +l d a
  gi|2613562   594 ALHTGDLILFTAVG-MFPTSDHFHQVVTPMMLTIDRYLSLKAPKTLDDLA 642  

                   iGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLt
                    G++L ++VL++q  SkRy P V++     +     p     ++   P+t
  gi|2613562   643 TGAYLSTLVLQYQAFSKRYMPSVMNVCLNTIA-AVAP-----QKASWPGT 686  

                   FerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvda
                   F         +     ++       +  + +L   D      t+      
  gi|2613562   687 FPVH------E---PAADVRLLSTKKGAIRKLKISD-----CTP------ 716  

                   lrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslke..sl
                              +++ E   e    l AF E f P l++ s+++  +++ l
  gi|2613562   717 ----------QEQTKEQRQELKLALLAFTETFGPALEMISQLTKPKnsQL 756  

                   pekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEn
                   p + l   l+ ++ ++  l  +a+  r PL l  H+P+aI +  PKFE  
  gi|2613562   757 PPT-LVDQLEKVILKLRILSNSARLARRPLELHHHRPLAIKMGIPKFEDS 805  

                   yDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlR
                   +     P k  yDpD+ R+el+KL+a +KrE+KGA+RElRKDa+F++r+ 
  gi|2613562   806 F----DPNKH-YDPDRDRAELAKLRAEHKRERKGAMRELRKDARFMQREN 850  

                   lkEkaakdqerhEKmkkivnelqeqegAl<-*
                   l  k akd ++  K k++v+e+q +eg +   
  gi|2613562   851 LRVKKAKDEAYEKKYKRLVAEIQNEEGRE    879  

gi|190345785|gb|EDK37729.2|: domain 1 of 1, from 35 to 761: score 423.5, E = 3.3e-124
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +e+ r+   K + +i+ +fN Fd + ++ K d+     t+ Kg   k
  gi|1903457    35    SETRRQDHNKIISEIRNDFNQFDNRYNRTKHDV--T--TISKGKFVK 77   

                   PGVSRakaeekR.....krTl....eaefkkknKsgafiDkRiGErnkhL
                   +G S++  e  R++++  ++l++++ea++k + ++g+ +D+R+GE n   
  gi|1903457    78 VG-SKQHNEASRnnqsvEQALksehEAKKKFRGRTGGLVDRRFGEGNANM 126  

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   +     EeKMl+Rf REr S  +  K+ a  l     D+eedG+      
  gi|1903457   127 T----AEEKMLIRFARERESGNK--KKHAFSLG---SDDEEDGAEDD--- 164  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                    DD   l++ g    d++ L d +             +  +a+  +r   
  gi|1903457   165 -DDGFVLTHGGKAIADEESLGDQV----------TYADENSAQPLRR--- 200  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   KsK+EVm+E+IaKSK+yK+ r+Ke  +  D+i  LDe f d++  ++ e+
  gi|1903457   201 KSKAEVMKEVIAKSKFYKQQRQKEFAKTQDEIMDLDEDFGDVM-QVMNEQ 249  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +       K+p   k+    eYD+ ++E+  + RA P+dRTKT EEl ++
  gi|1903457   250 PV-----PKQPIKSKTAEEIEYDSRVRELTYDRRAVPADRTKTDEELRKE 294  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                    aek r+LEeeR kRM +    e g+                +dD  D  
  gi|1903457   295 HAEKMRKLEEEREKRMSGFAS-EGGDN---------------IDD--D-- 324  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                             f+e              dEd+ e+   + +    ++    
  gi|1903457   325 ----------FWE-----------NDQDEDEMEGVSIENG---ASS---- 346  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                                          D     ++ e e+ +            
  gi|1903457   347 -----------------------DSD---EESETEVTS------------ 358  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                        + k +a k                              P t  e+
  gi|1903457   359 ----KSSKPKAAKHA---------------------------IPSTQTEF 377  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                   +  +++    + p  V+ I   hhp L+++N Kek+  F  +L qh+  L
  gi|1903457   378 ISIVEGVEPSQQPRLVNSIVESHHPRLAAGN-KEKMDVFVGILFQHV--L 424  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                   +     ++ k        + L+e  i+++  l e ++  l e ++    +
  gi|1903457   425 Y-----LADKD-------KELTETYISILVPLAENYNQALVENVRTELQQ 462  

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                    +  +        +   dLv+F  +g lFsTSD +HlVvTPal+lm e  
  gi|1903457   463 VQNHILDQ----KLRTRDLVLFAVIGVLFSTSDHYHLVVTPALILMNEAI 508  

                   s..rspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                   s+++ +  Slk  a   +L   VL +q+i kRyvPeV  +lq +L   lv
  gi|1903457   509 SstQFRQVSLKQLAEAVYLSDMVLHYQRIAKRYVPEVACFLQRALM-ALV 557  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                   p   Ve l  +P  F +             n++ +  +  + +  Ls  D
  gi|1903457   558 P--QVEKLGGKP-EFNLK-----------PNDKRKNKVQ-ISISGLS-ED 591  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                         +++f+      SlL    +leL    v  +   +   EI  P  
  gi|1903457   592 ------SPDFKF-----SLLDR--ILELCDRSVSMWRDNSGIVEITAPLI 628  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                     L  +     ++      +l   + ++ Kl e a ker PLAlq HK +
  gi|1903457   629 PILTHLAR---YFNN-ELTNLAAILTKIVKLHENAVKERVPLALQTHKAL 674  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                   aI++ +PKFEEn+    +Pdk+SyD  +eR e+nK+k++lK+EkK +++ 
  gi|1903457   675 AIPTYAPKFEENF----NPDKKSYDANRERQEINKMKHQLKKEKKSTMKD 720  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +RK  +F ar+ +  k +   e+h Km+ iv  +++ egA+   
  gi|1903457   721 IRKQGRFSAREQIRDKKQMYEEYHKKMANIVSSISTTEGAE    761  

gi|146420400|ref|XP_001486156.1|: domain 1 of 1, from 35 to 761: score 421.9, E = 1e-123
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +e+ r+   K + +i+ +fN Fd + ++ K d+     t+ Kg   k
  gi|1464204    35    SETRRQDHNKIISEIRNDFNQFDNRYNRTKHDV--T--TILKGKFVK 77   

                   PGVSRakaeekR.....krTl....eaefkkknKsgafiDkRiGErnkhL
                   +G S++  e  R++++  ++l++++ea++k + ++g+ +D+R+GE n   
  gi|1464204    78 VG-SKQHNEASRnnqsvEQALksehEAKKKFRGRTGGLVDRRFGEGNANM 126  

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   +     EeKMl+Rf REr S  +  K+ a  l     D+eedG+      
  gi|1464204   127 T----AEEKMLIRFARERESGNK--KKHAFSLG---SDDEEDGAEDD--- 164  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                    DD   l++ g    d++ L d +             +  +a+  +r   
  gi|1464204   165 -DDGFVLTHGGKAIADEESLGDQV----------TYADENSAQPLRR--- 200  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   KsK+EVm+E+IaKSK+yK+ r+Ke  +  D+i  LDe f d++  ++ e+
  gi|1464204   201 KSKAEVMKEVIAKSKFYKQQRQKEFAKTQDEIMDLDEDFGDVM-QVMNEQ 249  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +       K+p   k+    eYD+ ++E+  + RA P+dRTKT EEl ++
  gi|1464204   250 PV-----PKQPIKSKTAEEIEYDSRVRELTYDRRAVPADRTKTDEELRKE 294  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                    aek r+LEeeR kRM +    e g+                +dD  D  
  gi|1464204   295 HAEKMRKLEEEREKRMLGFAS-EGGDN---------------IDD--D-- 324  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                             f+e              dEd+ e+   + +          
  gi|1464204   325 ----------FWE-----------NDQDEDEMEGVSIENG---------- 343  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                                            +  + dEe+e E             
  gi|1464204   344 ------------------------AS-SDSDEELETEV------------ 356  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                      + + k +a k                              P t  e+
  gi|1464204   357 --TSKSSKPKAAKHA---------------------------IPSTQTEF 377  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                   +  +++    + p  V+ I   hhp L+++N Kek+  F  +L qh+  L
  gi|1464204   378 ISIVEGVEPSQQPRLVNSIVESHHPRLAAGN-KEKMDVFVGILFQHV--L 424  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                   +     ++ k        + L+e  i+++  l e ++  l e ++    +
  gi|1464204   425 Y-----LADKD-------KELTETYISILVPLAENYNQALVENVRTELQQ 462  

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                    +  +        +   dLv+F  +g lFsTSD +HlVvTPal+lm e  
  gi|1464204   463 VQNHILDQ----KLRTRDLVLFAVIGVLFSTSDHYHLVVTPALILMNEAI 508  

                   s..rspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                   s+++ +  Slk  a   +L   VL +q+i kRyvPeV  +lq +L   lv
  gi|1464204   509 SstQFRQVSLKQLAEAVYLSDMVLHYQRIAKRYVPEVACFLQRALM-ALV 557  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                   p   Ve l  +P  F +             n++ +  +  + +  Ls  D
  gi|1464204   558 P--QVEKLGGKP-EFNLK-----------PNDKRKNKVQ-ISISGLS-ED 591  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                         +++f+      SlL    +leL    v  +   +   EI  P  
  gi|1464204   592 ------SPDFKF-----SLLDR--ILELCDRSVSMWRDNSGIVEITAPLI 628  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                     L  +     ++      +l   + ++ Kl e a ker PLAlq HK +
  gi|1464204   629 PILTHLAR---YFNN-ELTNLAAILTKIVKLHENAVKERVPLALQTHKAL 674  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                   aI++ +PKFEEn+    +Pdk+SyD  +eR e+nK+k++lK+EkK +++ 
  gi|1464204   675 AIPTYAPKFEENF----NPDKKSYDANRERQEINKMKHQLKKEKKLTMKD 720  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   +RK  +F ar+ +  k +   e+h Km+ iv  +++ egA+   
  gi|1464204   721 IRKQGRFSAREQIRDKKQMYEEYHKKMANIVSSISTTEGAE    761  

gi|50416593|ref|XP_457562.1|: domain 1 of 1, from 35 to 781: score 413.8, E = 2.9e-121
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdi....lGrsKtkvK.
                      +e+ r  K+     i+k+fN+Fd k ++ K+d++  ++G+    vK 
  gi|5041659    35    SETRRNDKQEILSNIRKDFNLFDGKINRTKRDVtmiqGGK---FVKv 78   

                   geeGkPGVSRaka..eekRkrTleaefkkknKsgafiDkRiGErnkhLsG
                   g +      Rak + e   k   e  +k+  K+g+ +D+R+GE+n  L+ 
  gi|5041659    79 GSKQHSDATRAKSdvENSMKLQYELDKKQHGKTGGLVDRRFGENNRNLT- 127  

                   DqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKD
                       EeKMleRf+REr  Q   SK++  n+  G +D  +d d  g     
  gi|5041659   128 ---AEEKMLERFTRER--QGT-SKKKI-NFALGSDDEQDDEDNDGF---- 166  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFeeeDA...eaeeeqrGA
                       l+++g +Ls+d  L+d           ++ +eD   +e  +++r  
  gi|5041659   167 ---VLTHSGKSLSLDNDLDDSK------SNTKYYDEDSlmpEEVQPKR-- 205  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                    KsK+EVm+E+IaKSK+yK  r+ e  +  D+i +LD+ f d++ +    
  gi|5041659   206 -KSKQEVMKEVIAKSKFYKHQRQMEFQKAQDEIMNLDDEFGDIMTEFN-N 253  

                   kltsRKsGiKkprea..kedtDaeYDlllkEMvfekRAsPsdRTKTeEEl
                    ++      Kkp+  ++k++   eYD +++E+  + R  P+dRTKT +El
  gi|5041659   254 NPA------KKPQSFsnKTPEEIEYDNKVRELTYDRRSVPADRTKTADEL 297  

                   AqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLd
                    ++   +L +LE  Rl+RM+++  + + E+                dDL 
  gi|5041659   298 QKEHDTRLQKLEADRLRRMNGDYDDREAEA----------------DDLE 331  

                   DsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndG
                               Gf+                     ++ed++   +    
  gi|5041659   332 ------------GFWN--------------------GSEDEEE--GFAI- 346  

                   tdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlk
                                             D +  e+++  ++ E         
  gi|5041659   347 --------------------------DNS-AEEEGSSSGNE--------- 360  

                   dLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                               + +++   +K+                    i  P th
  gi|5041659   361 -------DDMDQSKPSGRTLKKT-------------------IIQIPGTH 384  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   e++++ l+  d   +   ++++i  ++p L+e+N Ke++  F  +L +hI
  gi|5041659   385 EDFIASLSSVDESNHCNYIKKVIETYQPRLAEGN-KERMNVFVGILFKHI 433  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                     L+  l++ +       +  + +++ L  l+ +  ek    l e+++  
  gi|5041659   434 --LH--LANDPCPP---AENINETMKILKKLSESYNEK----LVEVIRVE 472  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                   i+  +e++ +          dLv+F +vg lFsTSD +HlVvTP l+lm 
  gi|5041659   473 INDIQERIFNL------QPRDLVYFVMVGYLFSTSDHYHLVVTPTLILMN 516  

                   evLsrspvs...SlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLf
                   e+ s +p +++++ ++I  Glf+v i L +q  SkR+ Pe+v +l+++ +
  gi|5041659   517 ESISSIPYDkktTVSRIGQGLFIVDILLNYQTFSKRFTPEIVCFLEKAAL 566  

                   tllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrL
                    ll+p          P   e+                +++ +++ ++ + 
  gi|5041659   567 -LLIP---------EP---EKL---------------TNQSLSINKIIKS 588  

                   slaDLVtqti..teef.pvdal...rsSlLliKEvleLvEeiveiyyklq
                     + L t+ i++te++ +v  l +++s  L  K +  L+  +  i     
  gi|5041659   589 D-TNLRTKGIkpTEDLvKVSELfgnDSQVLKLKLTNKLIDIFARILSIWR 637  

                   AFiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerK
                     +E+++ Il   s + +  s+     + kl   +e+ +K      kerK
  gi|5041659   638 -DNEVMIEILSSFSNLANHLSIHYN--SPKLNQLIEKMSKIQNNLIKERK 684  

                   PLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkakl
                   PL lq HK ++I + +PKFEEn+    +Pdk+SyD  +eR elnK k ++
  gi|5041659   685 PLTLQHHKAISIATFAPKFEENF----NPDKKSYDVNRERQELNKIKNQI 730  

                   KrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegA
                   K+E+K + + +RK +kF ar+ +  k  k  e+h Km+ ivn +++ egA
  gi|5041659   731 KKERKSTLKDIRKESKFTARQQIADKKDKYDEYHKKMANIVNSISTIEGA 780  

                   l<-*
                   +   
  gi|5041659   781 E    781  

gi|199429947|emb|CAG85573.2|: domain 1 of 1, from 62 to 808: score 413.8, E = 2.9e-121
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdi....lGrsKtkvK.
                      +e+ r  K+     i+k+fN+Fd k ++ K+d++  ++G+    vK 
  gi|1994299    62    SETRRNDKQEILSNIRKDFNLFDGKINRTKRDVtmiqGGK---FVKv 105  

                   geeGkPGVSRaka..eekRkrTleaefkkknKsgafiDkRiGErnkhLsG
                   g +      Rak + e   k   e  +k+  K+g+ +D+R+GE+n  L+ 
  gi|1994299   106 GSKQHSDATRAKSdvENSMKLQYELDKKQHGKTGGLVDRRFGENNRNLT- 154  

                   DqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKD
                       EeKMleRf+REr  Q   SK++  n+  G +D  +d d  g     
  gi|1994299   155 ---AEEKMLERFTRER--QGT-SKKKI-NFALGSDDEQDDEDNDGF---- 193  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFeeeDA...eaeeeqrGA
                       l+++g +Ls+d  L+d           ++ +eD   +e  +++r  
  gi|1994299   194 ---VLTHSGKSLSLDNDLDDSK------SNTKYYDEDSlmpEEVQPKR-- 232  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                    KsK+EVm+E+IaKSK+yK  r+ e  +  D+i +LD+ f d++ +    
  gi|1994299   233 -KSKQEVMKEVIAKSKFYKHQRQMEFQKAQDEIMNLDDEFGDIMTEFN-N 280  

                   kltsRKsGiKkprea..kedtDaeYDlllkEMvfekRAsPsdRTKTeEEl
                    ++      Kkp+  ++k++   eYD +++E+  + R  P+dRTKT +El
  gi|1994299   281 NPA------KKPQSFsnKTPEEIEYDNKVRELTYDRRSVPADRTKTADEL 324  

                   AqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLd
                    ++   +L +LE  Rl+RM+++  + + E+                dDL 
  gi|1994299   325 QKEHDTRLQKLEADRLRRMNGDYDDREAEA----------------DDLE 358  

                   DsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndG
                               Gf+                     ++ed++   +    
  gi|1994299   359 ------------GFWN--------------------GSEDEEE--GFAI- 373  

                   tdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlk
                                             D +  e+++  ++ E         
  gi|1994299   374 --------------------------DNS-AEEEGSSSGNE--------- 387  

                   dLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                               + +++   +K+                    i  P th
  gi|1994299   388 -------DDMDQSKPSGRTLKKT-------------------IIQIPGTH 411  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   e++++ l+  d   +   ++++i  ++p L+e+N Ke++  F  +L +hI
  gi|1994299   412 EDFIASLSSVDESNHCNYIKKVIETYQPRLAEGN-KERMNVFVGILFKHI 460  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                     L+  l++ +       +  + +++ L  l+ +  ek    l e+++  
  gi|1994299   461 --LH--LANDPCPP---AENINETMKILKKLSESYNEK----LVEVIRVE 499  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                   i+  +e++ +          dLv+F +vg lFsTSD +HlVvTP l+lm 
  gi|1994299   500 INDIQERIFNL------QPRDLVYFVMVGYLFSTSDHYHLVVTPTLILMN 543  

                   evLsrspvs...SlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLf
                   e+ s +p +++++ ++I  Glf+v i L +q  SkR+ Pe+v +l+++ +
  gi|1994299   544 ESISSIPYDkktTVSRIGQGLFIVDILLNYQTFSKRFTPEIVCFLEKAAL 593  

                   tllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrL
                    ll+p          P   e+                +++ +++ ++ + 
  gi|1994299   594 -LLIP---------EP---EKL---------------TNQSLSINKIIKS 615  

                   slaDLVtqti..teef.pvdal...rsSlLliKEvleLvEeiveiyyklq
                     + L t+ i++te++ +v  l +++s  L  K +  L+  +  i     
  gi|1994299   616 D-TNLRTKGIkpTEDLvKVSELfgnDSQVLKLKLTNKLIDIFARILSIWR 664  

                   AFiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerK
                     +E+++ Il   s + +  s+     + kl   +e+ +K      kerK
  gi|1994299   665 -DNEVMIEILSSFSNLANHLSIHYN--SPKLNQLIEKMSKIQNNLIKERK 711  

                   PLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkakl
                   PL lq HK ++I + +PKFEEn+    +Pdk+SyD  +eR elnK k ++
  gi|1994299   712 PLTLQHHKAISIATFAPKFEENF----NPDKKSYDVNRERQELNKIKNQI 757  

                   KrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegA
                   K+E+K + + +RK +kF ar+ +  k  k  e+h Km+ ivn +++ egA
  gi|1994299   758 KKERKSTLKDIRKESKFTARQQIADKKDKYDEYHKKMANIVNSISTIEGA 807  

                   l<-*
                   +   
  gi|1994299   808 E    808  

gi|74180014|dbj|BAE36550.1|: domain 1 of 1, from 19 to 786: score 412.2, E = 8.7e-121
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     eK           NPF+vkv++ KF ilGr   k ++++G 
  gi|7418001    19    GASGGPEK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|7418001    55 PGVSRARAIRKRTQTLLKEYKERNKSNVFADKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|7418001   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|7418001   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ l +  k++  
  gi|7418001   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILMS-RKPK-- 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +D  YD  ++E+ fe  A+Ps R KTeEElA++E e+
  gi|7418001   236 KSEDKEKKE-KPQPDE-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQER 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L +LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|7418001   284 LKKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|7418001   318 -----GFILDKDD-----RRLLSYKDGKMNIEDVQEEQSKEADGQENDQK 357  

                   eavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedea
                          E eDD    E ED++  eD Ee ed  S + l+   +  e+  
  gi|7418001   358 -------EGEDDS---EEEDES-HEDSEESEDPDSHSDLESNIESEEENE 396  

                   qplk.......geaikasvkeKANmKKsadTiPASLdrsipFtidcPkth
                    p k+++++++g+ +k     KA   K            +p+ +  P ++
  gi|7418001   397 TPKKeqrqtpgGKLPKDD--QKA--QKAVAA-------ELPYVFAAPESF 435  

                   eelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhI
                   eel  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I
  gi|7418001   436 EELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI 484  

                   KDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                        Dl+         +    kLv +L++l q +Pe +  s + +l++ 
  gi|7418001   485 ----GDLATDSTPD---LKTIDKLVVHLYSLCQMFPESASDSIRFVLRDA 527  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                     e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPall m+
  gi|7418001   528 MHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALLCMS 577  

                   evLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   + L ++pv Sl+d+ +Glf + ++L+++s S+R++Pe++++l +iL+   
  gi|7418001   578 QMLTKCPVMSLQDVIKGLFVCCLFLEYVSLSRRFIPELFNFLLGILY-IA 626  

                   vpKRDVells....itPLtFerdRLDslekGLPldnlfavkestllepqr
                    p    + +s++++++  +F     +  ++   l+++  + ++t      
  gi|7418001   627 TP----NTKSqgstLVH-PFRAL--GKNSE---LLVVSDKADVTTWQRGS 666  

                   LslaD...LVtqtiteefpvda.lrsSlLliKEvleLvEeiveiyyklqA
                   L+l   ++L t t te+  +++++++S L+           v  y  l++
  gi|7418001   667 LPLHWanrLSTLTATEANHTRLsCVASCLSL------MKHCVLMYQALPS 710  

                   FiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKP
                   F  If P +aLLs+     slp+      l   ++ +    e  k+   P
  gi|7418001   711 FHAIFRPHQALLSKHLADCSLPQE-----LQELAQSILSAMEGQKQHCRP 755  

                   LAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklK
                   L   + KPv +    P+   +       + +                   
  gi|7418001   756 LVYEKSKPVPLKQFTPRLVKVL----EFGRK------------------- 782  

                   rEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl
                                                                 +g  
  gi|7418001   783 ----------------------------------------------QGSS 786  

                   <-*
                      
  gi|7418001     -     -    

gi|241953351|ref|XP_002419397.1|: domain 1 of 1, from 42 to 818: score 402.4, E = 7.8e-118
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k+  r eK +   +i+ +fN Fd k ++ K di         g   k
  gi|2419533    42    KSFNRDEKLQQLKEIRDQFNKFDQKINRSKHDISII----HQGKFVK 84   

                   PGVSRak.......aeekR..krTleaefkkknKsgafiDkRiGErnkhL
                   +G S++ +++  +++  +R+ k     e+ +  K+g+++DkR+GE++ hL
  gi|2419533    85 VG-SKQHnssaiknGNIQRqmKMQYDLEKFQHGKTGGILDKRFGENDSHL 133  

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   +     EeKMl+Rf+ Er  Q+  S ++   ++  + D+e d        
  gi|2419533   134 T----KEEKMLARFTKER--QSAASSKKRSVFS-LASDDEQDESEEDE-- 174  

                   KDDlDs...leelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqr
                     D D++  l++ g  Ls+ddE+                 + ++++ +++
  gi|2419533   175 --DDDGgfmLTHGGNTLSLDDEETINY------------VDEDSLQPPKK 210  

                   GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlslla
                      KsK EVm+EiIaKSK+yK+ r+Ke  +  D+id+LDe f d++  l 
  gi|2419533   211 ---KSKNEVMKEIIAKSKFYKQQRQKEFAKTQDQIDELDEDFGDVMDDLR 257  

                   mekltsRKsGiKk.........preakedtDaeYDlllkEMvfekRAsPs
                     +    K   K++++++++++ +  k++   eYD +++E+  + RA P+
  gi|2419533   258 NVQSQISKNNTKDggsggstngGFSTKTPEQIEYDNKVRELTYDRRAVPA 307  

                   dRTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkkl
                   +RTKT EE+ ++ ++k  +LE  RlkRMe+ +   d E            
  gi|2419533   308 ERTKTDEEIRKEHEDKMKKLEADRLKRMEGFID-DDRET----------- 345  

                   kvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaeds
                       +dDLd             f+                 d d+   + 
  gi|2419533   346 ---QGDDLDN-----------DFWA--------------GSDNDSDGNEA 367  

                   dDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEE
                   d+    n+             d  ++D +       ke e D+ +De   
  gi|2419533   368 DGFTIKNS-------------DHHESDSE-------KE-EQDQNQDESHK 396  

                   SDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsip
                                      k   i +                        
  gi|2419533   397 ----------------REVKSQKITNV----------------------- 407  

                   FtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvK
                       +P t ee+++  +  d    p  V+RI   + p L+e+N Kek+ +
  gi|2419533   408 ---IMPFTIEEFIQEMSNVDPIKQPEYVKRICETYKPSLAEGN-KEKMSN 453  

                   FsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqe.lPekla
                   F  vL  +I  L+   ++Q +     f+ + k    L e + ++    ++
  gi|2419533   454 FVGVLFEYI--LH--VANQ-YQD---FEPFVKILRKLAESSTSkTATNYN 495  

                   islseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHl
                    sl ++++e ik  + ++ k      +  +dLvfF +++ lFs SD +H+
  gi|2419533   496 ESLVQRVREHIKHIQSRIDKQ-----LTPGDLVFFAIIAYLFSSSDHYHI 540  

                   VvTPalllmaevLsrspv..sSlkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   V+TP+l+lm + Ls +  ++ +  dIa G +L  + L +q+  kR+ Pe+
  gi|2419533   541 VITPSLILMNQILSNIIYhpKTVTDIAHGVYLIDVLLMYQRFAKRFDPEI 590  

                   vyalqqiLftllvpKRD....VellsitPLtFerdRLDslekGLPldnlf
                   +++++ +Lf +++p  D+ ++ +llsi P t  ++      +       f
  gi|2419533   591 INFIEHALF-MMIPEIDkmntSKLLSISP-TAGNI-----TL------QF 627  

                   avkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiv
                   a   s ++    +s+       i   +    l  S L +   ++L    v
  gi|2419533   628 AMNKSEKICSLEESTLS-----IKQLYDEENLNKSCLIS-KLIQLMDKCV 671  

                   eiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKlte
                   + ++  ++ iEI+  +   L  ++  +    +         + + + l +
  gi|2419533   672 TLWKEKSSLIEILESFISILKHITK-YNAIVT------GPILTKFTRLYA 714  

                   dakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRsel
                      k rKPL lq HK +aI + +PKFEEn+    +Pdk+SyD+ +eR el
  gi|2419533   715 NLVKDRKPLTLQHHKAIAIATYAPKFEENF----NPDKKSYDINRERQEL 760  

                   nKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivne
                   nK k+ lK+EkK A + +R   kF+ar+ + Ek     ++h Km+ ivn 
  gi|2419533   761 NKVKHELKKEKKAALKDIRQENKFIAREQISEKKRMYEDYHKKMANIVNS 810  

                   lqeqegAl<-*
                   +q +egA+   
  gi|2419533   811 IQSEEGAE    818  

gi|19684184|gb|AAH26035.1|: domain 1 of 1, from 19 to 796: score 397.0, E = 3.2e-116
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1968418    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1968418    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1968418   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1968418   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1968418   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1968418   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1968418   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1968418   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D    + +   e EE     ++ k  
  gi|1968418   368 ---------EDTEESDSP------DSH-LDLESNVESEE-----ENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1968418   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1968418   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1968418   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1968418   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1968418   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1968418   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|1968418   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1968418   715 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   n     +P                             
  gi|1968418   760 PVPLKLFTPRLVSNS----RPQVI-------------------------- 779  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                     +     +         +   q +A    
  gi|1968418   780 -----------------HLPWPPNY---------RCEPQHPAK    796  

gi|119602896|gb|EAW82490.1|: domain 1 of 1, from 19 to 796: score 396.9, E = 3.4e-116
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1196028    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1196028    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1196028   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1196028   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1196028   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1196028   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1196028   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1196028   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1196028   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1196028   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1196028   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1196028   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1196028   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1196028   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1196028   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|1196028   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1196028   715 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   n     +P                             
  gi|1196028   760 PVPLKLFTPRLVSNS----RPQVI-------------------------- 779  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                     +     +         +   q +A    
  gi|1196028   780 -----------------HLPWPPNY---------RCEPQHPAK    796  

gi|145603109|ref|XP_362025.2|: domain 1 of 1, from 32 to 869: score 396.4, E = 4.9e-116
                   *->keedreeKKK......AvakiqkefNPFdvkvakr..KFdilGrsKt
                        ++++ K K+ +++ A   i+++fNPF  + + r++KF +  +   
  gi|1456031    32    AQDAQATKEKrlkrsvALDGIREQFNPFQFHTNARgpKFEVTTKTNA 78   

                   kvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLs
                        +G PGV + ++ee  +  l   +    +          E+++   
  gi|1456031    79 STSRIKGRPGVAKSIGEE--RASLPNWLLTQAR----------ENDPSMA 116  

                   GDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDvee...dGdrggs
                        Ee  l Rf  E+    r S ++   ++  lED+ ++ +++++g s
  gi|1456031   117 ----PEERALQRFAMEK---QR-SHKKGSIFD--LEDDGDevsLTHMGKS 156  

                   SvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaee....
                      DD D + e +     + E a     + +l   r e++   +e++++ 
  gi|1456031   157 LTFDDDDDFDEADLPSETESEIAKIN--VSRLKRMRGEDDNSDGEDgeel 204  

                   eqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLls
                   + r  kK+K+E+ +EiI KSK  K Er+  Ke  eDl++k D  f dL +
  gi|1456031   205 PER--KKTKQEIYKEIIEKSKAHKYERQQIKEADEDLREKIDGEFADLRN 252  

                   llamekltsRKsGiKkprea......kedtDaeYDlllkEMvfekRAsPs
                   ll  ++ +  + G   +++    + +k   D+ YD  +k +v +kRA+Ps
  gi|1456031   253 LLYTTSAKPERPGAEAEQPKlvagmeKDKFDKAYDVRVKQLVQDKRAQPS 302  

                   dRTKTeEElAqkEaekLreLEeeRlkRMeete...EledgEeEiGGEESv
                    RTKT EE+A++E ++L eLEe RlkRM++ e ++E e++Ee    EES 
  gi|1456031   303 SRTKTDEEKAAEESARLKELEEKRLKRMRGEEvsdE-EEEEE----EESS 347  

                   kklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEd....d
                        +  + +dD f           ++++  R    + + ddEd+   d
  gi|1456031   348 DESDEGESE-EDDEFQL---------GKGIKMRPTATELGFDDEDdfiiD 387  

                   deeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDd
                   d++ +   D + + +                +eDD+  AE    e e D 
  gi|1456031   388 DDLVASGSDIEPEDS----------------DEDDESDAESSGSEAEADG 421  

                   EeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPA
                    e edE                   l +  ik+   e +   K  d    
  gi|1456031   422 DESEDEF--------------TKGLLTETEIKNA--EFT--AKNGDA--- 450  

                   SLdrs..ipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLke
                     d s+++pFt++cP+th elle  k    +   ++++RI+ +hh KL+ 
  gi|1456031   451 -KDDSdgVPFTFPCPRTHAELLEITKEVPVAKLTTVIQRIRALHHSKLAM 499  

                   eNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLiela
                   +N Ke+l+ Fs vL qhI   +  l + d  +       e L  + ++la
  gi|1456031   500 GN-KERLGVFSRVLVQHI--AH--LGNSDAPSA----PIEGLIRHVHSLA 540  

                   qelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllF
                   +  P    ++++  l  + +e   +++k          dL+    +g+++
  gi|1456031   541 KTYPLEISREFRLHLQAIGNERPLAIVKG---------DLMIMTAIGSIY 581  

                   sTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSk
                   +TSD  H VvTPa+l+ma +L +s  ++l   a Gl+L+ + L++q  Sk
  gi|1456031   582 PTSDHFHRVVTPAMLTMARYLGQSVPRTLANYATGLYLAILSLQYQAFSK 631  

                   RyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldn
                   RyvPeV++ +   L+  l p    e+l   P     +     e       
  gi|1456031   632 RYVPEVMNSVLNTLL-ALAPVEYAEELGFFPVHRPTP-----EI---RMK 672  

                   lfavkestllepqrLslaDLVtqtitee.fpvdalrsSlLliKEvleLvE
                   +   + + +l  +  s       t ++  ++v  l++S L +      + 
  gi|1456031   673 DGQGQTVGKLNCHDCSSSS----TKSPNcLKVAILDTS-LKV------LS 711  

                   eiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkekl.ldavelve
                    + + + + +AF E f      Ls +++ +   ++ l+  + + a+ l  
  gi|1456031   712 SAADLWSGKSAFFETFETATKVLSHLTS-KACKSH-LPPSIvKEATRLQK 759  

                   Klte...dakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDp
                    lt++ ++a+  r PL l  HKPvaIr+ +PKFE  +     P k  yDp
  gi|1456031   760 HLTAslnSARLSRRPLELHHHKPVAIRTYVPKFEDSF----DPNKH-YDP 804  

                   DkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEK
                   D+eR+el+KL+a +K+E+KGA+RElRKDa F+ar++l  k  kd ++  K
  gi|1456031   805 DRERAELAKLRAEHKKERKGAMRELRKDANFMAREKLRIKKVKDEAYEKK 854  

                   mkkivnelqeqegAl<-*
                     +iv+e+q++eg +   
  gi|1456031   855 FQRIVAEIQTEEGRE    869  

gi|68465617|ref|XP_723170.1|: domain 1 of 1, from 43 to 828: score 395.2, E = 1.1e-115
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k   r eK +   +i+ +fN Fd k ++ K di         g   k
  gi|6846561    43    KNINRDEKLQQLKEIRDQFNKFDQKINRSKHDISII----HQGKFVK 85   

                   PGVSRak.......aeekR..krTleaefkkknKsgafiDkRiGErnkhL
                   +G S++ +++  +++  +R+ k     e+ +  K+g+++DkR+GE++ hL
  gi|6846561    86 VG-SKQHnssaiknGNMQRqmKMQYDLEKFQHGKTGGILDKRFGENDSHL 134  

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynln....DGlEDveedGdrg
                   s     EeKMl+Rf+ Er  Q+  S ++   ++  ++D  E +e dG+  
  gi|6846561   135 S----KEEKMLARFTKER--QSG-SSKKRSVFSlasdDEQEPDESDGEDN 177  

                   gsSvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeq
                   g         l++ g  Ls+ddE+                +eD   +++ 
  gi|6846561   178 GG------FMLTHGGNALSLDDEETINY-----------VDEDSLQQQPP 210  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLl...
                   +  kKsK EVm+EiIaKSK+yK+ r+Ke  +  D+id+LDe f d++++ 
  gi|6846561   211 K--KKSKNEVMKEIIAKSKFYKQQRQKEFAKTQDQIDELDEDFGDVMddl 258  

                   .sllamekltsRKsGiKkp...reakedtDaeYDlllkEMvfekRAsPsd
                   ++  +  ++t   sG  k ++ +  k++   eYD +++E+  + RA P++
  gi|6846561   259 rNVQSQISKTTANSGSGKAdgvFSTKTPEQIEYDNKVRELTYDRRAVPAE 308  

                   RTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklk
                   RTKT EE+ ++ +ek  +LE  Rl+RMe+     d +             
  gi|6846561   309 RTKTDEEIRKEHEEKMKKLEADRLRRMEGFVD-DDRDT------------ 345  

                   vrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsd
                      +dDLd             f+                 + d e  + +
  gi|6846561   346 --QGDDLDN-----------DFWA----------------GSDRENDENE 366  

                   DddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEES
                     d+                                +   D+E D+ EE 
  gi|6846561   367 A-DGFTI-----------------------------K-NSDQESDSEEE- 384  

                   DaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipF
                               +  qp  +  +k     K        T           
  gi|6846561   385 ------------EQYQPPHKRQVKSQ---KI-------T----------- 401  

                   tidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKF
                      +P t ee+++  +  d    p  V++I   + p L+e+N Kek+ +F
  gi|6846561   402 SVIMPFTIEEFIQEMSNVDPNKQPEYVKKICETYKPNLAEGN-KEKMSNF 450  

                   svvLLqhIKDLfEDlseQdikknLNfqLLekLveaLie............
                     +L  +I  L+   ++Q +     f+ + k    L e++++++ ++ ++
  gi|6846561   451 VGILFEYI--LH--IANQ-YQD---FEPFVKILRKLAEsstssrattitt 492  

                   ..laqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLv
                   ++ +     +++ sl e+++e ik  + ++ k      +  +dLvfF ++
  gi|6846561   493 ttTTTTTTKAYNESLVERVREHIKHIQSRIDKQ-----LTPGDLVFFTII 537  

                   gllFsTSDfrHlVvTPalllmaevLsrspv..sSlkdIaiGlfLvsiVLk
                   + lFs SD +H+V+TP+l+l+ + Ls +  ++ +  dIa G +L  + L 
  gi|6846561   538 AYLFSSSDHYHIVITPSLILINQILSNIIYhpKTVTDIAHGVYLIDVLLM 587  

                   fqsiSkRyvPeVvyalqqiLftllvpKRD....VellsitPLtFerdRLD
                   +q+  kRy Pe++ +++ +Lf +++p  D+ ++ +llsi P t +    +
  gi|6846561   588 YQRFAKRYDPEIISFIEHALF-MMIPEVDkldtLKLLSISP-TAATA--G 633  

                   slekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLl
                   s          f    s ++   ++++       i   +  d+ +sSl +
  gi|6846561   634 SITV------QFSMNKSEKI-CSQEQTLS-----IKQLYEEDLNKSSLIS 671  

                   iKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkekl
                       ++L    v+ ++  ++ iEI+  +   L  ++    +  + +   +
  gi|6846561   672 K--LIQLMDKCVTLWKEKSSLIEILESFISILKHITK---YNAT-VAGPI 715  

                   ldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdk
                   l +   +        k rKPL lq HK +aI + +PKFEEn+    +Pdk
  gi|6846561   716 LTKFTRLHANLV---KDRKPLTLQHHKAIAIATFAPKFEENF----NPDK 758  

                   sSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdq
                   +SyD  +eR elnK k+ lK+EkK A + +R   +F+ar+ + Ek     
  gi|6846561   759 KSYDVNRERQELNKVKHELKKEKKAALKDIRQENRFIAREQISEKKRMYD 808  

                   erhEKmkkivnelqeqegAl<-*
                   ++h Km+ ivn +q +egA+   
  gi|6846561   809 DYHKKMANIVNSIQSEEGAE    828  

gi|119602899|gb|EAW82493.1|: domain 1 of 1, from 19 to 800: score 394.7, E = 1.6e-115
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1196028    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1196028    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1196028   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1196028   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1196028   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1196028   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1196028   282 EQEHLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1196028   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1196028   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1196028   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1196028   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1196028   482 --GDLATDDPPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1196028   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1196028   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1196028   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I+ P
  gi|1196028   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                    +aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1196028   715 LQALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+   +                                    
  gi|1196028   760 PVPLKLFTPRLVKVL----------------------------------- 774  

                   RElRKDakFvarlRlkEkaakdqerhEKmkki....vnelqeqegAl<-*
                            v+  R +            + +++ ++  +   q +A    
  gi|1196028   775 ---------VSNSRPQ------------VIHLpwppNYRCEPQHPAK    800  

gi|238880894|gb|EEQ44532.1|: domain 1 of 1, from 43 to 824: score 394.1, E = 2.4e-115
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k   r eK +   +i+ +fN Fd k ++ K di         g   k
  gi|2388808    43    KNINRDEKLQQLKEIRDQFNKFDQKINRSKHDISII----HQGKFVK 85   

                   PGVSRak.......aeekR..krTleaefkkknKsgafiDkRiGErnkhL
                   +G S++ +++  +++  +R+ k     e+ +  K+g+++DkR+GE++ hL
  gi|2388808    86 VG-SKQHnssavknGNMQRqmKMQYDLEKFQHGKTGGILDKRFGENDSHL 134  

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynln....DGlEDveedGdrg
                   s     EeKMl+Rf+ Er  Q+  S ++   ++  ++D  E +e dG+  
  gi|2388808   135 S----KEEKMLARFTKER--QSG-SSKKRSVFSlasdDEQEPDESDGEDN 177  

                   gsSvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeq
                   g         l++ g  Ls+ddE+                +eD   +++ 
  gi|2388808   178 GG------FMLTHGGNALSLDDEETINY-----------VDEDSLQQQPP 210  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLl...
                   +  kKsK EVm+EiIaKSK+yK+ r+Ke  +  D+id+LDe f d++++ 
  gi|2388808   211 K--KKSKNEVMKEIIAKSKFYKQQRQKEFAKTQDQIDELDEDFGDVMddl 258  

                   .sllamekltsRKsGiKkp...reakedtDaeYDlllkEMvfekRAsPsd
                   ++  +  ++t   sG  k ++ +  k++   eYD +++E+  + RA P++
  gi|2388808   259 rNVQSQISKTTANSGSGKAdgvFSTKTPEQIEYDNKVRELTYDRRAVPAE 308  

                   RTKTeEElAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklk
                   RTKT EE+  + +ek  +LE  Rl+RMee     d +             
  gi|2388808   309 RTKTDEEIRREHEEKMKKLEADRLRRMEEFVD-DDRDT------------ 345  

                   vrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsd
                      +dDLd             f+                 + d e  + +
  gi|2388808   346 --QGDDLDN-----------DFWA----------------GSDRENDENE 366  

                   DddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEES
                     d+                   n+D +      D e ee++ ++     
  gi|2388808   367 A-DGFTI---------------KNSDQE-----SDSE-EEEQDQLPHKR- 393  

                   DaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipF
                                  q    +  +                          
  gi|2388808   394 ---------------QVKSQKITSVI------------------------ 404  

                   tidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKF
                      +P t ee+++  +  d    p  V++I   + p L+e+N Kek+ +F
  gi|2388808   405 ---MPFTIEEFIQEMSNVDPNKQPEYVKKICETYKPNLAEGN-KEKMSNF 450  

                   svvLLqhIKDLfEDlseQdikknLNfqLLekLveaLie..........la
                     +L  +I  L+   ++Q +     f+ + k    L e++++++ ++  +
  gi|2388808   451 VGILFEYI--LH--IANQ-YQD---FEPFVKILRKLAEsstssrattiTT 492  

                   qelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllF
                        +++ sl e+++e ik  + ++ k      +  +dLvfF +++ lF
  gi|2388808   493 TTTTKAYNESLVERVREHIKHIQSRIDKQ-----LAPGDLVFFTIIAYLF 537  

                   sTSDfrHlVvTPalllmaevLsrspv..sSlkdIaiGlfLvsiVLkfqsi
                   s SD +H+V+TP+l+l+ + Ls +  ++ +  dIa G +L  + L +q+ 
  gi|2388808   538 SSSDHYHIVITPSLILINQILSNIIYhpKTVTDIAHGVYLIDVLLMYQRF 587  

                   SkRyvPeVvyalqqiLftllvpKRD....VellsitPLtFerdRLDslek
                    kRy Pe++ +++ +Lf +++p  D+ ++ +llsi P t +    +s   
  gi|2388808   588 AKRYDPEIISFIEHALF-MMIPEVDkldtLKLLSISP-TAATA--GSITV 633  

                   GLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEv
                          f    s ++   ++++       i   +  d+ +sSl +    
  gi|2388808   634 ------QFSMNKSEKI-CSQEQTLS-----IKQLYEEDLNKSSLISK--L 669  

                   leLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldav
                   ++L    v+ ++  ++ iEI+  +   L  ++    +  + +   +l + 
  gi|2388808   670 IQLMDKCVTLWKEKSSLIEILESFISILKHITK---YNAT-VAGPILTKF 715  

                   elveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyD
                     +        k rKPL lq+HK +aI + +PKFEEn+    +Pdk+SyD
  gi|2388808   716 TRLHANLV---KDRKPLTLQQHKAIAIATFAPKFEENF----NPDKKSYD 758  

                   pDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhE
                     +eR elnK k+ lK+EkK A + +R   +F+ar+ + Ek     ++h 
  gi|2388808   759 VNRERQELNKVKHELKKEKKAALKDIRQENRFIAREQISEKKRMYDDYHK 808  

                   KmkkivnelqeqegAl<-*
                   Km+ ivn +q +egA+   
  gi|2388808   809 KMANIVNSIQSEEGAE    824  

gi|169603327|ref|XP_001795085.1|: domain 1 of 1, from 83 to 875: score 387.8, E = 1.9e-113
                   *->keedreeKKKAvakiqkefNPFdv.kvak.rKFdilGrsKtkvKgee
                      + ++r+    A a i++ fNPF+ ++ a+++KF          K   
  gi|1696033    83    NADARAQRHSALASIRESFNPFEFkHLARpKKFEYVSQNADNSKRVL 129  

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                   G PGV +  +ee Rk+ l  e   +nK g+++D+RiGE ++  s     E
  gi|1696033   130 GRPGVTKSQGEEARKKSLLPEMNRRNKVGGILDRRIGEDDPTMS----LE 175  

                   eKMleRfsRErmSQlrLSKreaynlnDGlE...DveedGdrggsSvKD..
                   +KM++Rf RE+  Q +   r  + ++  lE+++D   +++ g+s   D++
  gi|1696033   176 DKMMARFEREQ--QKK---RGGNVFD--LEdgdDEFQLTHGGQSMTFDhe 218  

                   .....DlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqr
                    ++++D D    +g +  +d  L       ++    + e eDA  eeeq 
  gi|1696033   219 igdeeDYDAASVSGSSDGEDGFLKRKR---RRDDVDGEEPEDAAPEEEQP 265  

                   GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlslla
                     kKsK+EVm+E+IaKSKl K Er+++Ke   Dl+++LD+   d+l  l 
  gi|1696033   266 ERKKSKAEVMKEVIAKSKLHKYERQAQKEDDDDLREELDKDLNDVLAALR 315  

                   ..mekltsRKsGiKkpreakedt......................DaeYD
                   ++m k+        +p  +ke ++++ + + ++     ++++  +D+eYD
  gi|1696033   316 ghMNKKP-------EPEAPKEAPkgdfgmnadraallagssqaakDKEYD 358  

                   lllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEle
                     ++ M  + RA+P++RTKTeEE+A +Ea +L +LEe R+kRM++    +
  gi|1696033   359 TRVRQMLQDARAKPTERTKTEEEKAREEAKRLKKLEEKRMKRMRGEPV-S 407  

                   dgEeEiGGEESvkklkvrSvdD..LdDsfsVEEDKPKfGfiedlle...R
                   d Ee          +k   vdD+++   +s  +D   fG      ++++R
  gi|1696033   408 DDEE----------PKQKEVDDdeEEEFDSENDDAAEFGLKT-AAQpssR 446  

                   EDNvdNeEddE.dddeeaedsdDddsvndGtdlkqkKeavLkddEneDDd
                    + vd e d+  ddd  a ds+      d             +dE +D  
  gi|1696033   447 PEGVDDEDDFIlDDDLVATDSEA-----D-----------ISGDESDDAS 480  

                   LGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvk
                      E++D+     dE D d+                  p+k +a +  v 
  gi|1696033   481 ---EIDDTM--AMDEDDADFL-------------KDVLPEKPKAQSKAVN 512  

                   eKANmKKsadTiPASLdrs.ipFtidcPktheelleLlkkldleDkplIV
                             Ti A    s++++t++cP++heell   k+ +  D+p+++
  gi|1696033   513 GVL-------TIGADTTSSkLAYTYPCPRSHEELLKVFKDVAASDVPTVI 555  

                   eRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfq
                   +RI+ ++h  L+ +N K kl  F  +L  h+   +  ls Q       + 
  gi|1696033   556 QRIRALYHAGLHSDN-KNKLADFACALVDHV--KY--LSDQTPPAS--LT 598  

                   LLekLveaLielaqelPeklaislseellevikelaeeykknEhikyPSl
                     e    + ++l+++ + +       + +e  k+ +++  +      P  
  gi|1696033   599 VIESMIRHIHSLSRSYSAR----IATQFREHLKQIQAS--ND-----PTP 637  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                   +dL ++  +g  ++TSD  H VvTPa+  ma        +S kd+a G++
  gi|1696033   638 GDLALLTAIGTTYPTSDHFHQVVTPAITVMARWMGLTTPNSTKDVATGAY 687  

                   LvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerd
                   +  + L++q+ SkRyvPe++       +                 ++ + 
  gi|1696033   688 IGAVCLQYQRLSKRYVPELIR------Y---TS------------LCLKS 716  

                   RLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsS
                                           p++ +                     
  gi|1696033   717 ------------------------PHTTP--------------------A 722  

                   lLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlk
                   +L        + ++ + +   ++F EIf P  a L    +++s +++   
  gi|1696033   723 ILAA--HSKNILTAADLWSNSPSFTEIFTPLIAPLKS-ANQKSTLQT--- 766  

                   eklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRs
                           l   lt  a+  r P  l  H+P+ I +  PKFEE +     
  gi|1696033   767 --------LNARLTT-ARLRRRPQLLHDHRPLPIKTSIPKFEESF----D 803  

                   PdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaa
                   P k  yDpDkeRse +KL +  KrEkKGA RElRKD+ F+ar++l Ek  
  gi|1696033   804 PNKH-YDPDKERSEAAKLQKEYKREKKGALRELRKDSNFIAREKLREKKE 852  

                   kdqerhEKmkkivnelqeqegAl<-*
                   kd ++  K k++v+e+q +eg +   
  gi|1696033   853 KDAAYESKYKRLVAEIQGEEGRE    875  

gi|164657706|ref|XP_001729979.1|: domain 1 of 1, from 42 to 945: score 385.3, E = 1.1e-112
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      + +  +  +K         N Fd +va  K   lG    kvKg+ G 
  gi|1646577    42    GQYRAQQRRKRLEALMTNLNAFDERVASSKNQALGA---KVKGASGR 85   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P   +   +++R+  l  e++ ++ s+ f D+R+GE n+h s     E+K
  gi|1646577    86 PANAKSSSIQQRRERLLPEYQNRHHSSSFHDRRFGEYNPHMS----LEDK 131  

                   MleRfsRErmSQl.rLSKreaynlnDGlEDveedGdrggsSvKDDlDsle
                   Ml Rf+ Erm   ++ S+ ++  lnD  + ++++++ g+s     l ++ 
  gi|1646577   132 MLKRFTHERMHRIpKTSNTSLFDLNDDDDADLTLTHYGQS-----LSGMD 176  

                   elgeeLsdddELade...aLDkdflalkrFeeeDAeaeeeqrGAkKsKkE
                   el + + ddd  +d +++ +D+  +   +F + D+      + A  sK E
  gi|1646577   177 ELPDVRLDDDNDDDNprgHIDANMTRDEHFAGFDDAEDPDAAQAPRSKHE 226  

                   VmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll.....amek
                   Vm+E+IaKSKl K Er+K K+  e l+ +LD+   d+ sll ++++  ++
  gi|1646577   227 VMKEVIAKSKLAKHERQKVKDADEELRMELDDELGDIRSLLfsrpsTETS 276  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +    +      +a + +D  YD +++EM  e RA+P dR+KT EElAq 
  gi|1646577   277 VD-VAATERAATPASSKGDT-YDAFVREMAYERRAKPQDRLKTAEELAQD 324  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                    a +L+e E  Rl+RM++    e+gE+          l    +dD dD  
  gi|1646577   325 QAKRLEEAESARLRRMRGELD-EEGEA----------LMDYAIDDDDDHE 363  

                   s.........VEEDKP.....KfGfiedlleREDNvdNeEddEd..ddee
                   ++ +++ ++ V  D P++ +++fG + +l e      ++E dEd + d+e
  gi|1646577   364 NdansnvkraVKTDEPrtmrsRFGLGHGLDE--QSSAASENDEDagQDTE 411  

                   aedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeD
                    + ++  d                +d E +DD+ G + ED     D  eD
  gi|1646577   412 TAMEEEYDVDEE------------EDNESDDDE-GDDAEDSA---DNDED 445  

                   edEESD..aEldvlkdLKedeaqpl....kgea........ikasvkeKA
                    dE  D+ a l  ++ L     +p++++++ +a+++++++ + as +e  
  gi|1646577   446 GDEN-DtaAQLADYQNLEQYGEAPYtpqtVNKAepqptrrlPRAS-SERV 493  

                   NmKKsadTiPASLdrsipFtidcPktheelleLlkkldle..DkplIVeR
                         +T        +pFt++cP th+++l+Ll+ +  ++++  ++++R
  gi|1646577   494 ------ST--------LPFTFPCPSTHDAFLDLLEQHQVApsQLHTVISR 529  

                   IikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLL
                   I+++h p L eeN   kl  F  vL  h+  L+   + Qd   n  +  L
  gi|1646577   530 IRTLHAPNLGEEN-PVKLQRFLGVLVDHV--LY--RTSQDDATNEDLLVL 574  

                   ekLveaLielaqelPeklaislseellevikelaeeykk....nEhikyP
                   + Lv +   la   P ++a  +  +l  +   l      +  ++    +P
  gi|1646577   575 NDLVLHISDLATMYPLRAAEHFVAKLSLMQRNLMQGLAQgalePASRTWP 624  

                   SlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiG
                   Sl  L f++  gll++TSD  H+V TP lll a++L   +++Sl+d    
  gi|1646577   625 SLPELSFLRVCGLLWPTSDRWHAVTTPMLLLVAQYLAHARIRSLRDMGSA 674  

                   lfLvsiVLkfqsiSkRyvPeVvya...lqqiLftllvpKRD.....Vell
                   l+Lvs+V+  q+ S+R vPe  +a  +++  L+ l+  +R +++++V+ l
  gi|1646577   675 LYLVSLVSSAQRESRRIVPEALNAlfnISAMLLPLHHGRRMhgrspVKAL 724  

                   si.....tPLtFerdRLDslekGLPldnlfav....kestllep.qrLsl
                    ++ + +tP + e                f+++ + ++  ++ + + L  
  gi|1646577   725 AEefgipTP-DVEAQ----------HTHAFTIradaQPHAKVSLaHILTH 763  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                   aD          +  + +  lL     + L   +   y + +AF E f+P
  gi|1646577   764 AD-----AVSSSSAVQTQVDLLRM--CVALQMSFAKMYEGSPAFVELFMP 806  

                   IlaLLs..ryslkeslpekRlkeklldavelveKltedakkerKPLAlqe
                    l LL  +  +l+   p+        da+  +    e a + r  L lq 
  gi|1646577   807 MLFLLEigEAGLRDTAPSV--VSYVHDAATSIRSQLERAYASRHALRLQA 854  

                   HKPvaIrllePKFE.EnyDDKRsPdksSyDpDkeRselnKLkaklKrEkK
                   H+ ++I + +PKF +  +     P+    DpD eR+  +K++a lK+E+K
  gi|1646577   855 HRALSIATYAPKFDqQSF----DPKRA-TDPDTERAYAAKMRALLKKERK 899  

                   GAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   GAiRElRKDa+F a +R + + a+d ++  K  ki   +q +  +    
  gi|1646577   900 GAIRELRKDAQFLADEREQRRVAEDVAYKKKIDKILGGMQDERSEQ    945  

gi|114592952|ref|XP_526506.2|: domain 1 of 1, from 19 to 784: score 384.7, E = 1.6e-112
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1145929    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1145929    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1145929   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1145929   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1145929   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1145929   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e+Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1145929   282 EQERLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1145929   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1145929   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1145929   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1145929   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1145929   482 --GDLATDDPPD---LRVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1145929   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+    p
  gi|1145929   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATP 625  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl...
                    +      ++  +F     +  ++   l+++ a  ++       Lsl+  
  gi|1145929   626 NKASQGSTLVH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwa 669  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                     L   t te+   ++   S L +   l L+   v  y++l++F  I  P
  gi|1145929   670 SRLRAPTSTEANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAITGP 714  

                   IlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHK
                     aLL        + ++  ++ l    +      e+ k+   PL   + K
  gi|1145929   715 LRALLTDHLA---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSK 759  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv + l  P+  ++         s                          
  gi|1145929   760 PVPLKLFTPRL-AGL----EFPTS-------------------------- 778  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                           +Al   
  gi|1145929   779 -------------------------------------GNPPAL    784  

gi|262105033|gb|EEY63085.1|: domain 1 of 1, from 22 to 831: score 382.9, E = 5.5e-112
                   *->keedreeKKKAvakiqkefNPFdvk..vakrKFdilGrsKtkvKgee
                         + ++K           NPFdv+++++k K  + Gr   +vKg+ 
  gi|2621050    22    --RASSSK---------GSNPFDVRgnASKQKHEVIGR---RVKGAG 54   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                   + +   Ra ae kR++Tl+aef  +nKs++f+DkR GE+++ Ls     E
  gi|2621050    55 RNVAAARAEAERKRRKTLGAEFNARNKSNVFKDKRLGEQDPTLS----ME 100  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDl..D
                   +KM++Rf+ Er   ++L + +a  l D      +d +++++     +++D
  gi|2621050   101 DKMMARFQTER--KRKLRNASAFALHDSDSEQDDDDALFLTHKGAKItdD 148  

                   sleelgeeLsdddELadea...LDkdflalkrF.eeeDAeaeeeqrGAkK
                      +l  +  +ddE ++++++++D d     +F+++ ++  e  ++  +K
  gi|2621050   149 DYDQLNADGPLDDEDDSAEgrkMDRDIVNQLHFgGGKGDNDEGDGK--RK 196  

                   sKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                   + kEVm E+ +K KlyKaEr+K K   eD +dkLDe f d+  ll   ++
  gi|2621050   197 THKEVMHEVMMKAKLYKAERQKNKSSQEDATDKLDEGFADVRGLLE-FRP 245  

                   tsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkE
                   t R  G  k+  +ke+ D+  D+l +E  fe  A+ ++R   +EE A+kE
  gi|2621050   246 T-RANG--KELLPKEPMDD-FDKLTREFAFEAKAKATERRMSPEEAAAKE 291  

                   aekLreLEeeRlkRMeeteEledgEeEiG....GEESvkk.lkvrSv...
                   +++L eLE  R  RM++  E +d++   G++++G  S kk+++ +  +++
  gi|2621050   292 RDRLAELEKKRVARMNGADEESDSDS-DGkrkkGKKSKKKtPQLIMMppt 340  

                   .dDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDdd
                   +dDL D           G+     eR    ++eE+d+d+ e  e+s+  d
  gi|2621050   341 dDDLTD-----------GYAV--DERFAAEEAEEEDNDEEESDEESES-D 376  

                   svndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaE
                   s+                   +DDd     E k+ ee+ EeD+dE SD E
  gi|2621050   377 SEAE-----------------SDDD----KEEKK-EEEPEEDKDEDSDDE 404  

                   ldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtid
                    d lk       q   +ea  a+                     +pF ++
  gi|2621050   405 SDKLKR------QQDAEEA-AAE---------------------LPFVFE 426  

                   cPktheelleLlkkldl...eDkplIVeRIikahhpKLkeeNRKeklvKF
                   cP + eel  L k ++ +++e   lI eRI + + p L  eN K k+  F
  gi|2621050   427 CPESPEELASLFKQHARnspEKRGLILERIVTYYNPRLSVEN-KNKMKRF 475  

                   svvL.LqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklai
                    +vL  q++  +f  +++ +  k+     L  L +  + laq++   ++i
  gi|2621050   476 FAVLvRQLL--IF--AARYAGHKH----DLDALAKNMYTLAQQMGDTAGI 517  

                   slseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlV
                     +e l    k+l ++        +P l  L++Fk   + F+TSD rH V
  gi|2621050   518 VVRELLAQLFKRLHKRASTS---AWPTLPELLLFKALTSVFPTSDLRHNV 564  

                   vTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvya
                   v+P   l+ e+L r  v S ++    lf +s+ L   +   R+ PeVv +
  gi|2621050   565 VSPMETLLGESLARGSVTSPQEATQALFTASLSLDMTRGKERFMPEVVSF 614  

                   lqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestl
                   l  iL  +        ++s       rd      +   l+ + a ke  +
  gi|2621050   615 LTRILRAFVTS---SDENSTHW--LRRD------L---LEWVAAQKEGKM 650  

                   lepqrLslaDLVtqtiteefpvdalrsS.lLliKEvleLvEeiveiyykl
                     + rLsla            +  +  ++ L+    l L+  ++  y +l
  gi|2621050   651 PALPRLSLAG-----------SSSCNGVqVLSA--LLALLDAASAQYASL 687  

                   qAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKl...tedak
                   ++F E f P   LL+++      +e     k   +   ++Kl+++ e   
  gi|2621050   688 PSFDELFYPLYLLLHAIVK---QLEN---NKVSEVNAVISKLhtrLEACW 731  

                   kerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKL
                     r PL lq+  P  +++ +P F Eny       k+     k  ++l+ L
  gi|2621050   732 DARRPLRLQSFAPSTLPTFAPHFDENY----TVRKD-KTAPKDTAQLKQL 776  

                   kaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqe
                    ++ Kr++KGA RElR+Da F+ r++ kE  a   +  EK k i   l e
  gi|2621050   777 QRQVKRARKGAARELRRDAEFIHREKQKEEEARLAAKEEKQKEIRRWLEE 826  

                   qegAl<-*
                   q   +   
  gi|2621050   827 QNATF    831  

gi|189203035|ref|XP_001937853.1|: domain 1 of 1, from 34 to 819: score 380.7, E = 2.7e-111
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFd...ilGrsKtkvKge
                      + +  + K  A + i++ fNPF+ k   r  +++ +   +  + K  
  gi|1892030    34    NADHHARKASALQSIRESFNPFEFKHLARPHKheyVSAQAENAPKKI 80   

                   eGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                    G PGV +  +ee R++ l  e   knK g+++D+RiGE ++  s    +
  gi|1892030    81 LGRPGVTKSQGEEARRKSLLPEMHRKNKVGGILDRRIGEADPTMS----V 126  

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDv...eedGdrggsSvKDD
                   E+ M++Rf  E+   +r  Kr+ + ++  lED+ ++ e+++ g+s     
  gi|1892030   127 EDRMMARFEQEQ---SR--KRSGNVFD--LEDDadeVELTHGGQS----- 164  

                   lDsleelgeeLsdddELa.......deaLDkdflalkrFeeeDAea....
                       +  ++e  ++d  a +  +++d++ D   +   r  e+D ea+ ++
  gi|1892030   165 ----LRFDDEIGEEDYDAasvagssDDE-DGFMKKKRRIDEVDGEApate 209  

                   eeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdL
                   e++ r  kKsK+EVm+E+IaKSK yK Er+++Ke     +d LD+   d+
  gi|1892030   210 EQPER--KKSKQEVMKEVIAKSKQYKYERQAQKEDDDEMRDALDKDLGDV 257  

                   lslla.........mekltsRKs..GiKkprea......kedtDaeYDll
                   l  l ++ +++++++  + s + + G+   r a   +++  d D eYD+ 
  gi|1892030   258 LAALRghinkkpepDAPKESQRNdfGMNADRAAllagttQQDKDREYDSR 307  

                   lkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledg
                   ++ + ++ RA+P++RTKTeEE+A +Ea +L eLE+ R+kRM++    +d 
  gi|1892030   308 VRQLLLDQRAKPTERTKTEEEKAREEAGRLKELEQKRMKRMRGESV-SDD 356  

                   EeEiGGEESvkklkvrSvd...DLdDsfsVEEDKPKfGfiedlleREDNv
                   Ee          ++  + + ++ +dD +s  +D   fG       R + v
  gi|1892030   357 EE----------PQKKGKEadkEEDDMDSLPDDAAEFGLKAPGQLRPEGV 396  

                   dNeEdd.EdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDd..LG
                   + e d+  ddd  a ds+                      E +DD+++ G
  gi|1892030   397 EDEDDFiMDDDLVATDSEA---------------------EMSDDEseAG 425  

                   AELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeK
                     ++D+     dEeD d+                  p+ +e +ka     
  gi|1892030   426 SAIDDTM--AMDEEDADFL-------------KDVMPERKEQPKAV---- 456  

                   ANmKKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRI
                           T+ A     +++t++cP++heell   k  +  D  ++++RI
  gi|1892030   457 ----NGVLTLGAETTSKLAYTYECPRSHEELLKVFKNVAPNDTSTVIQRI 502  

                   ikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLe
                   + ++h  L ++N K kl  F  +L  h+   +  ls+Q    +  +   e
  gi|1892030   503 RALYHAGLRADN-KNKLADFVCALIDHV--SY--LSNQTPAAP--LAVIE 545  

                   kLveaLielaqelPeklaislseellevikelaeeykknEhikyPSlkdL
                       + +++a++ P   a  ++e l+          + n     P  +dL
  gi|1892030   546 AIIRHIHSMARSYPVQIATKFREHLKNLQ-------VSN----IPTPGDL 584  

                   vfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvs
                    +++ +g++F+TSD  H VvTPa+ lma         S +d+a G+f+  
  gi|1892030   585 ALLSAIGSIFPTSDHFHQVVTPAITLMARWMGLTSPASTQDVATGAFIGA 634  

                   iVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLD
                   + L++q+ SkRyvPe++      L+    p         tP         
  gi|1892030   635 LCLQYQRLSKRYVPELIRYTTLCLL---SP-------HATP-----T--- 666  

                   slekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLl
                          l++  a+  +t       s+++                     
  gi|1892030   667 -------LLAAHAKNVLTAA-----STYE--------------------T 684  

                   iKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkekl
                   +                 ++FiEIf P l      +l +s  ++ ++++l
  gi|1892030   685 S-----------------PSFIEIFTPLLP-----PL-KSSKQTPVHQNL 711  

                   ldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdk
                      + l+          r PL l  H+ + I +  PKFEE +     P  
  gi|1892030   712 SARLALAR-------SRRRPLLLHTHRALPIKTSIPKFEESF----DPNR 750  

                   sSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdq
                     yDpDkeR+e + L +  KrE+KGA+RElRKDa F+ar+ l Ek  kd 
  gi|1892030   751 H-YDPDKERAEAKRLQKDYKRERKGAMRELRKDAHFIARESLREKKEKDR 799  

                   erhEKmkkivnelqeqegAl<-*
                   ++  K +++v+e+q +eg +   
  gi|1892030   800 AYENKYRRLVAEIQGEEGRE    819  

gi|193643702|ref|XP_001950397.1|: domain 1 of 1, from 2 to 805: score 378.0, E = 1.7e-110
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k    +eK         + NPF+ + + +KF ilGr   k K e+Gk
  gi|1936437     2    KVKKNKEK---------QLNPFELHINNKKFTILGR---KSKNEVGK 36   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG+ R k ++kRk+ l  e+k k Ks+ f+D+RiGE+n   +      + 
  gi|1936437    37 PGIARSKSIQKRKKSLLLEYKLKDKSNKFVDRRIGEKNRAMT----ADDR 82   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    ++Rf++ r   ++ + +     n  l   e++++ g+s     l  +e+
  gi|1936437    83 VIARFTASR---VK-AQKVYIIYN--LGEEEDLTHHGQS-----LSTIEK 121  

                   lgeeLsdddELadea.....LDkdflalkrFeeeDAeaeeeqrGAkKsKk
                        sddd   d+ +++++L + f   ++F++   +    ++    s +
  gi|1936437   122 FEKPMSDDDSDSDDDrnggkLAAEFVEKAHFGGGVLSRAGDGE---TSHR 168  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                     ++  Ia+SKl+K E+   K e   l++ LD+  k L++ +  +k    
  gi|1936437   169 DLIDKLIAESKLRKYEKKQLKQETNELTEQLDKDWKELMPVVP-TKNR-G 216  

                   KsGiKkpreakedtDae.YDlllkEMvfekRAsPsdRTKTeEElAqkEae
                      i ++ + k   D+ +YD+l + + f+ R+  sd++K eEE+A++E+e
  gi|1936437   217 ETDIEDEPPTKKKVDKNsYDILMRSLKFDRRGMASDKLKSEEEIAKEEKE 266  

                   kLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE
                   +L++LE eRlkRM++ e   dg             k+rS+dDLdD     
  gi|1936437   267 RLEKLESERLKRMKGIED--DGIV-----------KHRSADDLDD----- 298  

                   EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqk
                         G+i+  l           d+d+  +a+ s++     + tdl   
  gi|1936437   299 ------GYIL--LY------FDFGDDDIQPLAYNSEG---KPLNTDLISV 331  

                   Keav..Lkd....dEneDDdLGAELE.DkeGeeDdEeDedEESDaEldv.
                    e  ++L d+++ dEneD d   E+E+D+e e D+E  +d E    l ++
  gi|1936437   332 NEEQngLNDeenvDENEDED---EMEsDEE-ESDEEVEDDNENENNLNNd 377  

                   lkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti..dc
                    +dLKed      ++ i  +    A                +p+t+ +  
  gi|1936437   378 MSDLKEDDE----KKVIMDE----A-------------RQQLPYTFigTV 406  

                   PktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvL
                     ++e + e l++ +      I+eR ik +hp L  +N +++l  ++  L
  gi|1936437   407 AESYEGFQEILEDRSISEQTVIIERMIKVNHPSLGNDN-RSNLQRLYPYL 455  

                   LqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislsee
                   Lqh+     D  +  ++       L+ L ++L+ l+q +Pe +a +l+e+
  gi|1936437   456 LQHL----ND--NSCSIDG--WKILNTLAPHLYDLTQFFPEHAAKCLIEV 497  

                   llevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPal
                   l    ke+   ++     k    + L+f+kLv llF+ SD +H+V T a 
  gi|1936437   498 L----KEKHTDFVDS-SPKQITSDMLIFLKLVPLLFPPSDYYHPVCTYAV 542  

                   llmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiL
                   +  +e Ls+ ++  ++d+a  l L +i L+++  SkRy+PeVv+ l + L
  gi|1936437   543 MIASEILSQTKIKKRSDVASCLLLTTILLEYVQLSKRYIPEVVNMLRGML 592  

                   ftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavke....stll
                   + +         +s +   F         k L l+n  + +e ++++++ 
  gi|1936437   593 L-MATD---NSSISYVQ-QFKPN-----NKILTLENNETQTEwskkLSIN 632  

                   epqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqA
                   e+  +   D          +v  l s  L +  +l Lv  ++  +   ++
  gi|1936437   633 EIFSEKNID----------SVFKLTS--LYV--ILDLVFRFSKLCEDIPS 668  

                   FiEIflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKP
                    +EI  P l     +      +      k +  ++++ K+ e        
  gi|1936437   669 VNEIWAPHLSIITTLKINSDEMNA-QIDKTKLQLQAIDKKLE-------K 710  

                   LAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklK
                   L   + +P+a+rl eP+    y D R  +  S    ke++e+ KL+++ K
  gi|1936437   711 LQTISNRPKALRLYEPRIQKIY-DGRTFKTES----KEKAERSKLLHRYK 755  

                   rEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl
                   rE K A+RE+RKD +F + l+  E+a++d er  K+k i+     q +++
  gi|1936437   756 REMKSAVREIRKDNSFLSKLKYHEQAKSDVERRNKVKQIYSWGANQAHEI 805  

                   <-*
                      
  gi|1936437     -     -    

gi|149241272|ref|XP_001526295.1|: domain 1 of 1, from 37 to 850: score 372.4, E = 8.3e-109
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +e dr   K+    ++ +fN Fd + ++ K di         ge  k
  gi|1492412    37    NEIDRDLQKQNLLSVRDQFNKFDQRINRTKHDITIT----AGGEFVK 79   

                   PGVSRakaeekRkrTleaefkk........knKsgafiDkRiGErnkhLs
                   +G     a    k ++ ++ k++ + +++++n+ g+++DkR+GE++ h +
  gi|1492412    80 VGSKQHNATTAKKGAIQKQMKMqydlekrkRNRVGGVLDKRFGENDMHMT 129  

                   GDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvK
                        EeKMl+Rf+REr  Q   S ++    +  lE + +dG++      
  gi|1492412   130 ----QEEKMLARFTRER--QAATSGKKRGIYS--LESDDDDGEMAEGDND 171  

                   DDlDs.....leelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeq
                   DD D++++ +l+++g+ Ls+ddE+                +eD   e + 
  gi|1492412   172 DDEDEdggfqLTHSGQALSLDDEETVKY-----------VDEDQMVEGPP 210  

                   rGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll
                   r  kK+K+EVm+E+IaKSK+yK+ r+    +   +id+LDe f d++  l
  gi|1492412   211 R--KKTKAEVMKEVIAKSKFYKQQRQRDYAKTQNQIDELDEDFGDIMDDL 258  

                   amekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEE
                     +++       K ++  k++    YD +++E+  + RA P+dRTKT EE
  gi|1492412   259 RNTQKG----VAKPQFSTKTPEEIAYDNKVRELTYDRRAVPADRTKTDEE 304  

                   lAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDL
                   l ++ +ek  +LE+ Rl+RMe+     d E+               +dDL
  gi|1492412   305 LQKEHEEKIKKLEQDRLRRMEGFVT--DREA--------------EGDDL 338  

                   dDsfsVEEDKPKfGfiedlleREDNvdNeEddEddde.....eaedsdDd
                   +                dl +        Edd+ddd +  ++e+e ++D 
  gi|1492412   339 GE---------------DLGD--------EDDNDDDQqfwggESENEED- 364  

                   dsvndGtdlkqkKeavLkddEneDDdLGAELEDke...GeeDdEeDedEE
                        G   k  ++   ++ E e D+      D  +++G +++   ++EE
  gi|1492412   365 -----GFTIKEGRGEGEEEEEAEEDN------DNDndnGYDEQKGKKGEE 403  

                   SDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsip
                                    p   + + +s                       
  gi|1492412   404 --------------RGKPVSRKSPPIS----------------------- 416  

                   FtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvK
                       +P+  +e+  +lk+ldl + ++ ++ I  a+ p L+ +N K  + K
  gi|1492412   417 ----MPTDLDEFKSQLKDLDLSQQAKQIQIICDAYKPHLAMGN-KDLMNK 461  

                   FsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklai
                   F ++   ++  Lf  l+     +   fq ++     L  la +  e    
  gi|1492412   462 FVSIIFEYV--LF--LAD----E---FQEFQPILTILKKLASQYNEQ--- 497  

                   slseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlV
                    l e+ + +i     ++ k      +  +dL fF +vg lFsTSD +Hl+
  gi|1492412   498 -LVERMRVYILDIESRINKS--TLQLKPSDLAFFIIVGFLFSTSDHYHLI 544  

                   vTPalllmaevLsrspvsS...lkdIaiGlfLvsiVLkfqsiSkRyvPeV
                   vTP+l+l+ + Ls    +S+++l+ Ia+G fLv + L +q+i kR+ Pe+
  gi|1492412   545 VTPCLILINQILSNTIYRSkdeLRLIAMGIFLVDVLLTYQRIAKRFDPEI 594  

                   vyalqqiLftllvpKRDVellsi.........tPLtFerdRLDslekGLP
                   +++++ + + l  +   V  + + +++ ++++t  t  +    s +    
  gi|1492412   595 INFIEFAFLSLVPEPEKVDTNKLlsghipsttTTTTTNNN--NSNSG--- 639  

                   ldnlfavkestllepqrLslaDLVtqtit..eefpv...........dal
                        +   s+ l + +   ++    ti+ +e f+++++++++ + + + 
  gi|1492412   640 SNSSTTSSSSNQLNLVKSTKYE-ENSTISfgEIFKTtntnkeklhfnTQI 688  

                   rsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpek
                   +s lL     l         +   ++ iEI+  + a+L   +  +  +  
  gi|1492412   689 KSKLLIK--LLTIMDKTLSTWRDKSSIIEILESFIAMLKHFTK-YTSLTS 735  

                   RlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDD
                          + + + +Kl +   + r PL lq HK ++I +  PKFEEn+  
  gi|1492412   736 -------SYLTKFSKLLAASLQSRQPLQLQHHKSIGIATYTPKFEENF-- 776  

                   KRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkE
                     +Pdk+SyD+  eR +l+K ka+lK+E K A + +R   +F ar+ + E
  gi|1492412   777 --NPDKKSYDINVERQQLAKVKAQLKKEHKAALKDIRYENRFLAREQIGE 824  

                   kaakdqerhEKmkkivnelqeqegAl<-*
                   k +   e+h Km++ivn++q  eg +   
  gi|1492412   825 KKQMYDEYHRKMARIVNTIQADEGKE    850  

gi|198428459|ref|XP_002128116.1|: domain 1 of 1, from 23 to 848: score 349.9, E = 4.7e-102
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +  d+  K           NPF++k +k K  ilGr   k K ++G 
  gi|1984284    23    NTLDKVRK-----------NPFEIKINKQKHNILGR---KTKNDRGL 55   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka  kRk Tl  e+k +nK++ + D R+G ++   +     EeK
  gi|1984284    56 PGVSRSKANKKRKDTLLNEYKHRNKTNQIRDARFGLNDEQMT----IEEK 101  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggs.SvKDDlDsle
                   Ml Rfs Er    +    ++  +n  l+D+ee++++g+s S    +D + 
  gi|1984284   102 MLQRFSMER--KKK--HEKMAQFN--LNDDEELTHLGQSlSAIKQFDDFD 145  

                   elgeeLsdddELadeaLDkdflalkr..FeeeDAeaeeeqrGAkKsKkEV
                    ++ee   +     e   +   +++++ F     e+ +      K+ kEV
  gi|1984284   146 GSDEEDGPGGTMSGEY--VENAHFGGgfFTKKSSEGNDNEL--TKTRKEV 191  

                   meEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKs
                   ++ iIaKSKl K E+ +++e+   l++kLD+   d + l+    +  R s
  gi|1984284   192 IDDIIAKSKLAKFEKKAAREKSDELREKLDDAWSDFQKLIQ---PSVRTS 238  

                   GiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLr
                     K+     + +D  YD  +k M f+  A+Ps++ K e El  + a+ L 
  gi|1984284   239 QDKNTAKERSKPDE-YDMAVKQMLFDRKAAPSEKMKSEAELEEERAALLW 287  

                   eLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDK
                   + EeeR+ RM+ ++    +++        +k ++ S+d L   + V    
  gi|1984284   288 KQEEERIARMRMDGG--NEDA-------SRKRTHQSADALEE-DYV---- 323  

                   PKfGfiedlleRE.......DNvdNeEddEdddeeaedsdDddsvndGtd
                         e + + E+ + + +D  + +Ed+ +++ee e+   +d v +   
  gi|1984284   324 -----VEKVNQAEplsfnfdDEDEKSEDYVGENEEEEEDAPEDQVES--- 365  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                           L d    DD       D    e dE  +dE SD    +  d 
  gi|1984284   366 -------ELGDLGIVDDG-----GDSD-DENDEDQSDEFSDIDSGNEEDV 402  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti.dcPkthe
                      e qp + e + +   e                 ++  + ++ P ++ 
  gi|1984284   403 SSLEEQPDVVEDVVNKAEEEE---------------DVGEMLnKFPASYS 437  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                   e+  L++  +l     +V+  +k + p +  +N K k+  + +   qh  
  gi|1984284   438 EFSFLISSSALS-ASEVVSDLRKRFAPSIGKGN-KAKMIELFAYIWQHC- 484  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                          + + k    f   + L  + +el  ++Pe      se ++e  
  gi|1984284   485 -----CMVAAPKPD--FNIINSLISHAYELCALNPEN----CSECVKERL 523  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                   k+ + + +    i  PS + L+ FkL+ ll+sTSDf H+VvTPall++++
  gi|1984284   524 KRSYLSCVQASRIQLPSFEILIQFKLIKLLYSTSDFCHPVVTPALLFISH 573  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                    L  + v +l+d+++Gl+L+++  +++s SkRy+Pe  ++l   L  + v
  gi|1984284   574 LLDCCSVHTLRDVSKGLYLCTVAYEYVSFSKRYIPECLNFLTTVLC-MAV 622  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkes..tllepqrLsl
                   p  D   +   P t    R+         ++++ +   +++ l+p     
  gi|1984284   623 P--DKQNKADIP-TITSTRINGKNF--DILVVKKKNKFkeNQLKPDLSVM 667  

                   aDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP
                   +D        +    al+   L    +  L + +++ y   +A+ E+f  
  gi|1984284   668 MD-----ENNDINDTALVRCQLVA-TATRLTALFSTLYSEVPAYDEVFTK 711  

                   IlaLLsryslkeslpekRlkeklld.avelveKltedakkerKPLAlqeH
                   I     ++     + +  +  kl d++++ +e       k r P +  ++
  gi|1984284   712 IHSVCDKLKT-SFDRSNLVLAKLVDgVLKSIESNCQ---KPRTPISFGQR 757  

                   KPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGA
                   KP+ +r+   K          + k+S      + e+  L++k KrE KGA
  gi|1984284   758 KPKPLRMFDLKIDDTG---DPLRKKSKQTNALKRERDRLLHKRKREMKGA 804  

                   iRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   iRE RKD+kF+ar   kE+ a d er +K+k+++  l+ qeg++   
  gi|1984284   805 IREVRKDSKFIARHQQKEQEAMDAEREAKVKRLYGLLSNQEGEV    848  

gi|260793149|ref|XP_002591575.1|: domain 1 of 1, from 9 to 768: score 326.5, E = 5.5e-95
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                          r+ KKKA a +++  NPF+v+ ++ K  +lG+    ++ ++G+
  gi|2607931     9    ADFVRKNKKKAQADVKS--NPFEVRINRQKHNVLGK--KLRRFDKGM 51   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka+ kRk Tl +e++++ K++ f+D+R GE++++ +     E+K
  gi|2607931    52 PGVSRSKAIKKRKATLLQEYQQRDKRNQFVDRRLGENDPEMT----LEDK 97   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   Ml Rf  Er    +         +          d + s           
  gi|2607931    98 MLQRFAMER----K---------S----------DKPKS----------- 113  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                                                      +q+         +eE
  gi|2607931   114 -----------------------------------RQE--------MIEE 120  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                   iIa SK +K                            +  +++       
  gi|2607931   121 IIAQSKQRK----------------------------S--QPK------- 133  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                    +   k+  D+ YD+ ++E+ fe+ A+ sdR+KTe+ElA +E e+L +LE
  gi|2607931   134 -EDKVKPEADD-YDIMVRELGFEIKAKASDRLKTEDELAREEQERLQKLE 181  

                   eeRlkRMee.teEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPK
                     R  RM++ t+E+              + ++ S+dDLdD f     +P 
  gi|2607931   182 ADRQLRMKGlTQEDIRQQQ---------QNRHVSADDLDDGFDF--IRPE 220  

                   f...Gfiedll....................eREDNvdNeEddEdddeea
                   + +  + ++ l  +++++  +++++ ++++  R    ++    E d +e 
  gi|2607931   221 RlqlAYKDGKLllpegkelmpstsdadqkpiRRKHHSEAASGSEADQSED 270  

                   edsdDddsvndGtdlkqkKeavLkddEneDDdLGAELE......DkeGee
                   ed +D  s  d  d    K+    + E+eDDd G +LE++++ +D + ee
  gi|2607931   271 EDKED-HSDEDNSDQSEGKGSDQSEEEEEDDD-GSDLEsersadDDS-EE 317  

                   DdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeK....ANm...
                   ++Ee  dEE         d   +e++ +++e    + k K++++A m++ 
  gi|2607931   318 EQEEEGDEE---------DIDKEESEEEVEEREEKT-KRKqeteA-Meki 356  

                   .KKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIik
                   +KK    i  +  + +p+t+  P +  +l eLl++ +++   lI++RI+k
  gi|2607931   357 sKKERKAIAEAAKTELPYTFRAPESLKDLMELLEGQSYDRQLLIINRIRK 406  

                   ahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekL
                   +hhp L+e+N K+kl ++ ++LL +       l++Q       ++    L
  gi|2607931   407 CHHPSLAEGN-KKKLQNLFSILLEYF----GKLANQSPVA---MEMIDGL 448  

                   veaLielaqelPeklaislseellevikelaeey.....kknEhikyPSl
                     +L+elaq+ P      +  ++  v k ++ ++++  ++k     yP +
  gi|2607931   449 SIHLYELAQQSPGP----AADTVQTVLKNKYHKFdsvcqRKG-RAVYPAV 493  

                   kdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlf
                   ++L++FkLv+ +F+TSDfrH VvT a+l+ma+ L ++pv S++d+a Glf
  gi|2607931   494 DTLLLFKLVSVIFPTSDFRHSVVTSAMLFMAQILTKCPVTSGRDVACGLF 543  

                   LvsiVLkfqsiSkRyvPeVvyalqqiLftllvpK..RDVellsitPLtFe
                    ++++L+++s SkR+vPeV++ lq+ L+ l v K++R     +++P +F 
  gi|2607931   544 VCTLFLQYVSLSKRFVPEVINYLQGLLY-LAVKKesRKAATAEVVP-PFK 591  

                   rdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalr
                       +       l++l +  +s  + +  L+  D      +   p  + +
  gi|2607931   592 HT--GAQGN---LLVLQEPDDSRSMSIKPLP-LD-----YLSKNPAQDTD 630  

                   sSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekR
                   +                               +++LLs+  l   +p+  
  gi|2607931   631 T---------------------DD--------FSDLLSKHLLLAAYPQE- 650  

                   lkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDK
                   ++      ++lv++     +    PL   + KP+ + l ePKF E y   
  gi|2607931   651 VQDGRSQFLQLVTDHHS--QTTYPPLQYEKLKPKPLKLYEPKFDEDYNPE 698  

                   RsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEk
                   R  + s     +   e   L++ +KrE KGA+RE+RKDa+F ar+ l+E+
  gi|2607931   699 RKMKGS-----RKQKEKERLLKMHKREMKGAVREIRKDAQFLARQQLQEQ 743  

                   aakdqerhEKmkkivnelqeqegAl<-*
                     kd er  K+k i   l+ qeg+    
  gi|2607931   744 MDKDAERKRKVKEIMHHLSSQEGEC    768  

gi|241822923|ref|XP_002416603.1|: domain 1 of 1, from 14 to 843: score 312.2, E = 1.1e-90
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       +  +  K        ++ NPF+vkv+k   d+lGr   k K ++G 
  gi|2418229    14    ASAKVNGK------APERTNPFEVKVNKQRHDVLGR---KSKNDRGL 51   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSR ka+ kR  Tl +e+  +nKs+af+DkRiGE + +        +K
  gi|2418229    52 PGVSRSKAIKKRNETLLQEYVLRNKSSAFVDKRIGEFDSEMN----PDDK 97   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M +R   Er    +   ++   ++  l+  ee++++g s     +  +e 
  gi|2418229    98 MAARLAQER----K-ILQKKSVFS--LNEEEELTHLGKS-----INDMER 135  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                    ++ +sdd+ L d     df     F++    a        Ks kE+++ 
  gi|2418229   136 HDDPRSDDEDLYDKL-GRDFADKTNFGGFLTKADPSSD-SAKSRKEAIDQ 183  

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                    Ia+SK  K Er+ +K+e   l++ LD   k  + lla  +l+      K
  gi|2418229   184 LIAESKKLKYERQVQKDENFELTERLDNDWKQFQGLLASSRLK------K 227  

                   kpreakedtDaeYDlllkEMvfekRA.sPsdRTKTeEElAqkEaekLreL
                   kp ea+    + YD l+k + f +RA+  ++R KT +E A++E+  L++L
  gi|2418229   228 KPTEAEKESTDDYDVLVKQLRFAPRAgTATERVKTADEVAKEERKQLEKL 277  

                   EeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfs....VEE
                   E eR+ R ++  E  d+           +    S+dDLd  f ++++V E
  gi|2418229   278 ELERKLRAKGITE-RDSKK---------QWYFLSADDLDYNFYkqepVTE 317  

                   DKPKfGfiedlleREDNvdNeE.....ddEdddeeaedsdDddsvndGtd
                   D    G  e   e     d+eE+++++ddE +d  a + dD+ +  +  +
  gi|2418229   318 DADMSGDEE---E-----DAEEegsggDDEAEDKSASEGDDESGAESVEE 359  

                   lkqk...KeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvl
                     q  ++Ke   +   ++DDd      D  G  D E D+d +       l
  gi|2418229   360 IEQDvsgKEQAARQEDKSDDD------DDDGYSDLESDDDGS-------L 396  

                   kdLKedeaqplkgeaikasv............keKANmKKsadTiPASLd
                   ++     a    +ea+k sv ++ ++ +++  +eK   K  +  +P   +
  gi|2418229   397 QKETPPVAKGKAKEAPKTSViktckklqskaaSEKEGGKPVSKAVPEKKE 446  

                   rsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKe
                            P + ee+  L  +   + k+  V   ika++    +e + +
  gi|2418229   447 SRPTCIVTIPESEEEFSKLMADNTADEKACFVGDMIKANQ---GGEKKLK 493  

                   klvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPe
                   kl+ + v+LLqh+     D +     +   ++L  kL ++ + l q  P 
  gi|2418229   494 KLEMLFVFLLQHL----NDVAD----ED--LELVDKLCPHIYALVQISPT 533  

                   klaislseellevikelaeeykknEh......ikyPSlkdLvfFkLvgll
                            ll+vi+e+ e   k  +++ + +i +PS ++Lvf+k+vg  
  gi|2418229   534 T----CGRFLLDVISEKEEDLQKATErrarfgISFPSFSTLVFLKIVGQC 579  

                   FsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiS
                   +s SDf H+V TPa+l  ++ L  +  +   d   Glf  +++L++  +S
  gi|2418229   580 YSASDFSHIVATPAMLSASHMLTCCGLNGAADFLRGLFVTNVFLEYIAYS 629  

                   kRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPld
                   +R+ PeV+ +l+  L   + +           L   +             
  gi|2418229   630 RRFSPEVFVFLERLLS--HRE-----------LKLKKR------------ 654  

                   nlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvE
                   ++       +l++  L   D       e   +d+lr  +      + LvE
  gi|2418229   655 ADASGLLHEKLKLRLLGEED------VEM--TDQLRVEIIYA--GVKLVE 694  

                   eiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveK
                      e   +l++F E   P l  L ++     +p + ++   + ++  +  
  gi|2418229   695 KCAELSEGLPSFRELVDPLLKTLRKLEV-SAYPPT-VQSEVEKVISRLDR 742  

                   ltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeR
                   + e     rKPL + ++ P    lleP+F   +D ++            +
  gi|2418229   743 KVE-----RKPLRPEKRPPPMKQLLEPRFSMKFDGRKHFEGG-----QKK 782  

                   selnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkki
                   +el+ L  k+K+E KGA+RE R+D +F ar  lk +   d er EK+k i
  gi|2418229   783 AELKRLTYKHKKEMKGAMREVRRDNQFLARHILKDRIERDAERKEKVKQI 832  

                   vnelqeqegAl<-*
                   + el  qeg+    
  gi|2418229   833 YRELASQEGEY    843  

gi|47215158|emb|CAG12449.1|: domain 1 of 1, from 2 to 862: score 301.6, E = 1.7e-87
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                             K                           +           
  gi|4721515     2    -----HHK---------------------------K----------- 5    

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                              Rk Tl +e+k+k+Ks+ fiD+R+GE +         E+K
  gi|4721515     6 ----------YRKETLLKEYKQKHKSSKFIDRRFGEYDTKMA----PEDK 41   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    l Rf  Er   +   K+  ynln     +ee+++ g+s     l ++e+
  gi|4721515    42 ILQRFAMER--KRAYDKKDVYNLN----EDEELTHFGQS-----LAEMEK 80   

                   l.geeLsdddELadeaLDkdflalkrFee.........eDAeaeeeqrGA
                    +++  sdd+ +    L + ++a+ +F+++++  +++++++  ee +   
  gi|4721515    81 FtDFVNSDDESEEKGLLSAELTAS-HFGGgggllrkkpSGDQQEEDGSQR 129  

                   kKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllame
                    Ks +E +eE I KSK  K Er+++Kee   l++kLD+  k+++ l    
  gi|4721515   130 AKSRQELIEELILKSKQEKRERQAQKEEAQELTEKLDKEWKSIQALMVKK 179  

                   kltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAq
                    ++    G  +  + + +   eYD  ++E+ fe  A+Ps+++KT+EElA 
  gi|4721515   180 APK----GESDDKPEEKPKPEEYDMMVRELGFEMKAQPSEKLKTPEELAR 225  

                   kEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDs
                   +E+ekL +LE  Rl+RM  ++E   + +      S+ +  + S+dDL D 
  gi|4721515   226 EEREKLQKLEADRLRRM--MGE---EPA-----NSTQQQGHMSADDLNDG 265  

                   fsVE.EDKPKfGfiedlleREDNv.dNeEddEdddeeaedsdDddsvndG
                   f  +++DK    + ++    ED  ++   +dE + e+ e ++ +++ ++ 
  gi|4721515   266 FVLDsDDKKTLAYQDGKWNIEDETkELQDEDEEEEEGGETEEEEEGGSS- 314  

                   tdlkqkKeavLkddEneDDdLG.AELEDkeGeeDdEeDedEESDaEldvl
                          e   ++ E+eDD+ G+ +LE +  e + Ee   EE        
  gi|4721515   315 ----EEGEEEGEEEEEEDDEDGhSDLESEN-ESEAEEQNPEE-------- 351  

                   kdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkt
                      Ke  a pl  e +ka   e A                +p+t+  P +
  gi|4721515   352 ---KETSAKPLSQEEVKAQ-QEAA-------------KSELPYTFAAPES 384  

                   heelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvK...FsvvL
                     el +Ll ++  e   lIV R  k++hp L+ +N+ + +v +++ s++L
  gi|4721515   385 LSELEALLRGHTPENQRLIVARTLKCNHPSLAVGNKLKLQVRqppHSAAL 434  

                   LqhI......KDLf....EDlseQdikknLNfqLLekLveaLielaqelP
                     +++++ +++ Lf+   E    ++++ +  +    kL + L+ l q +P
  gi|4721515   435 RVYLstscpsQKLFgfllEYVGDLASRTPPELTAVDKLIPELYNLCQMFP 484  

                   eklaislseellevikelaeey.kknEhikyPSlkdLvfFkLvgllFsTS
                   e++     + l +    + e  ++k     +PSl+ Lv++k ++llF+TS
  gi|4721515   485 EAACKDVQSILGDAAHSMEEVLeVKG-RAAFPSLDMLVYLKVTALLFPTS 533  

                   DfrHlVvTPalllmaevLsr..............spvsSlkdIaiGlfLv
                   DfrH+V TPall +++ L r + +++++ ++   +pv+Sl+d+  Gl+L+
  gi|4721515   534 DFRHPVTTPALLYISQALTRvgathrrnlppaalCPVRSLQDVTSGLVLC 583  

                   siVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRL
                    +  +++s SkR+ Pe+v++l +iL+ l v  +      + P +F     
  gi|4721515   584 CLAVEYVSFSKRFMPELVNFLLGILH-LAVRDKAALGYTVAP-PFRAA-- 629  

                   DslekGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlL
                   + l     l++l             L+l       +  ++  d  r   L
  gi|4721515   630 GKLTD---LLVLSDSESCRSWSKKSLPLSSCQSLVLDTDLERDHHRLMCL 676  

                   liKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkek
                    +   l Lv      y+ l +F  I+ PI  LLs+      lp + l+e 
  gi|4721515   677 CV--CLDLVKRCCLLYKDLVSFTVILQPIRSLLSKHLTAQALPGT-LQEL 723  

                   lldavelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPd
                   ++  +e + +++      +  L   ++KP+ + ll PK  E+       +
  gi|4721515   724 HKEILEII-DSAP---VAHPRLVFEKKKPIPLKLLTPKIVEVL----DYG 765  

                   ksSyDpDkeRselnK..LkaklKrEkKGAiRElRKDakFvarlRlkEkaa
                   k+      +R+e+ K++Lk+k K+E KGA RElRKD++F ar++l E  +
  gi|4721515   766 KK---RGCTREEREKerLKHKYKKEFKGALRELRKDSSFLAREKLSEVIQ 812  

                   ...........................kdqerhEKmkkivnelqeqegAl
                   +  ++++++++++++++ ++++++ +  d er   +k +   l  qeg+ 
  gi|4721515   813 rcvgkrppsspegrsetcspsssslsfRDTERKRRVKELFGSLASQEGEW 862  

                   <-*
                      
  gi|4721515     -     -    

gi|115928458|ref|XP_784009.2|: domain 1 of 1, from 12 to 694: score 300.1, E = 4.8e-87
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +   + +K      +  + NPF+vk +k K  ilGr   k K+ +G 
  gi|1159284    12    SKVEQRSK-----ATEIKNNPFEVKINKQKHNILGR---KNKHGKGV 50   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P VSR k+++kR  Tl +e+k+++Ks+ f+DkR GE++++ s    +E+K
  gi|1159284    51 PVVSRSKGLQKRNATLLQEYKQRHKSNKFLDKRLGENDPEMS----VEDK 96   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+eRf+ E+  Q+   K  +y ln     +e++++ g+s     l sle+
  gi|1159284    97 MMERFTLEK--QRNHEKSGMYSLN----TDEDLTHYGQS-----LSSLEK 135  

                   lge.eLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVme
                     e++L  ddE+     Dk f a  +F++         +G  K+ +E+ e
  gi|1159284   136 FEEpDLASDDEEGGMI-DKKFVAEEHFGGFLTKKKTDEEGKPKTRQEIFE 184  

                   EiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGi
                   EiIaKSK  K  r+ eKe v +l++ LD  f d+    + + ++   s  
  gi|1159284   185 EIIAKSKKDKFNRQSEKEDVVKLTEQLDQDFNDV----SHYYPK---SRY 227  

                   KkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreL
                    +  e    +D+ YD ++kE++f+ RA+ sdR+KT+EElA++E+ekL++ 
  gi|1159284   228 RDKDEERRKPDD-YDMSVKELIFDMRAKASDRLKTPEELAKEEKEKLEKM 276  

                   EeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPK
                   E  R +RM++  E e+ E         ++ +  S+dDL D          
  gi|1159284   277 ETDRQRRMKGITETEEQEN-------KRRMQYLSADDLND---------- 309  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavL
                    Gf +                 d+       D  +v +            
  gi|1159284   310 -GFEL---------------TRDNRSTLSYRD--GVPS------------ 329  

                   kddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlk.dLKedeaqpl
                                     G+ D++ D+dE  D  +   k+ LK    q+ 
  gi|1159284   330 -----------------FGF-DQGMDDDED-DRTVKEIKsSLKKGNKQSV 360  

                   kgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkl
                    ++    +  eK   KK  +         +p+t++ P+  eel   l ++
  gi|1159284   361 TKKVSIQEPVEKK--KKIEEM-MRLAKEELPYTFKAPTCLEELEGVLTGH 407  

                   dleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQ
                   +     +I+eR ik+hhp L  +N K kl+ ++    q++   +    e 
  gi|1159284   408 SPSNQLTIIERMIKCHHPSLSDGN-KAKLETLTTCIYQLM-GKY--VKEG 453  

                   dikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykk
                     + +   q  + L+++L+ l+q    +      + l ++i e++e++ k
  gi|1159284   454 KDLQP---QFINGLTKHLYDLTQTCALA----SGNSLMGIICEKYESFNK 496  

                   nEh....ikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrs
                     +++++  +PSl+ L++FkLv+ lF+TSDfrH VvTP +l+m   Ls++
  gi|1159284   497 ETEdrgrSTFPSLDVLLYFKLVSALFPTSDFRHSVVTPTMLFMGAILSQC 546  

                   pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDV
                    v+S +d+ +Glf+++++Lk +s SkR+vPeV+++lq+iL+ +     + 
  gi|1159284   547 QVRSCQDVTFGLFICNLFLKNVSLSKRLVPEVMNFLQGILY-MASD-HES 594  

                   ellsitPLtFerdRLDslekGLPldnlfavkestllepqrLsl.aDLVtq
                   +   ++  +F +   + ++k   l+      e  l ++  L l +D    
  gi|1159284   595 KTAGLVVAPFKQS--GRFSK---LLRHEGTSEAQLRPVKILDLvTD---- 635  

                   titeefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLs
                     +e++    + +  L    +  L+  +++ y  l+++ EIf PI  LL+
  gi|1159284   636 --LEDLDQAEFSTWALGL--TCHLLHQFSTLYVDLPSYSEIFSPIYILLQ 681  

                   ryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrl
                       ke l+ k                                       
  gi|1159284   682 D---KELLLNK--------------------------------------- 689  

                   lePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKD
                           y                                         
  gi|1159284   690 --------Y----------------------------------------- 690  

                   akFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                     + +   
  gi|1159284   691 ---------------------------------HHDV    694  

gi|145351375|ref|XP_001420056.1|: domain 1 of 1, from 30 to 951: score 286.5, E = 5.8e-83
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      ++  +  K             F+    +rKFdilGr   kvKge+G 
  gi|1453513    30    SPSGVTVK-----------SAFETVSHRRKFDILGR---KVKGERGN 62   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   +   R+ a+ekR+rTl  e +   K +af+D+R+GE +  Ls    +EeK
  gi|1453513    63 VLQARTEAIEKRRRTLLVEHEANGKANAFLDRRFGEHDSGLS----VEEK 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                    + R    r+ Q +  K +a  ln   ED+ +dG   ++        l +
  gi|1453513   109 NIGRLAKARLRQYK--KSKAFALN---EDDDDDGFKTLT-------HLGQ 146  

                   lgeeLsd......ddELadeaLDkdflalkrFe............eeDAe
                   +  e++++ +++++dE++de LD   +   +F++++ +++ +++++e + 
  gi|1453513   147 PLGERDLtakpshGDEEDDENLDDEITRNFHFGggefeptlkrgdGEHDV 196  

                   aeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkd
                      e+r   KsKk VmeE IaKSK+yKaE++K+++  +D  dkLD  fk 
  gi|1453513   197 DAPERR---KSKKDVMEELIAKSKFYKAEKQKQRDDDGDMLDKLDSDFKA 243  

                   .....Llsl.....lamekltsRKsGiKkpreakedtDaeYDlllkEMvf
                    ++++Lls+  ++ +   k+t      K  +   +   +eYD   + + f
  gi|1453513   244 isqggLLSSalrkaVGHMKPT----AAKAAQTKAPEQKDEYDTWARTLAF 289  

                   ekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee...teEledgEeE
                   e R++  dR KT EE  ++++  L+  E  RlkRM+  +++ E +d +  
  gi|1453513   290 ERRGQAGDRAKTQEEVEAQAKLALEQAERKRLKRMRDvgsDDESSDDDGP 339  

                   iGGEESvkk.lkvrSvdDLdDsfsVEEDKPKfGfiedl.....leREDNv
                    GG    +++ k + +d  dD       K   G +edl+++ +le +D  
  gi|1453513   340 QGGYAARRRkVKKGDIDETDDALHGNNRKQHEG-GEDLdenfqLESDDDG 388  

                   dN.....eEddEdddeeaedsd..Dd..........dsvndGtdlkq...
                   +N+++++eEd  dd +e+ed d  Dd  + +++ +++  n  t+l q+++
  gi|1453513   389 ENedegsEEDVSDDESESEDDDalDDaarlrkslksELKNVDTELDQgkn 438  

                   ..kKeavL.........kddEneDDdLGAELEDkeGeeDdEeDedEES.D
                   + +K   L+++ + ++++ddE++DD+      D+   +D++ D+  E +D
  gi|1453513   439 rlRKLGILqdgveaedsEDDEDDDDE------DED-DDDEGSDDSQEVeD 481  

                   aEldvlkdL.......KedeaqplkgeaikasvkeKANmKKsad.TiPAS
                   a  dvl++ +++++ +Ked +    ++  k     K   KK + +T    
  gi|1453513   482 AHADVLREIedeedveKEDASNTARKSSQKEASTAKE--KKFSTpT---- 525  

                   LdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNR
                     ++ipFt+++P + e+l   l ++  eD  +I+ RI+ ++ p L++eN 
  gi|1453513   526 -RTDIPFTFPMPESAEDLNSILGDHNAEDAFTIITRIRACNAPTLAAEN- 573  

                   KeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqel
                   ++++  +   LLq      E l+ Q+ +    ++ L  L ++   l+ + 
  gi|1453513   574 RKRIQTLLGLLLQRF----EILAGQAPLP---VDHLDVLSKHIVDLSTQV 616  

                   PeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTS
                   P ++a  +  +++++  +l  + +   +  +P   + ++++L + +F+T 
  gi|1453513   617 PFFAATAAKARVEKMSTRLRQALRAG-ETGWPPSRTVLLLSLFAAIFPTT 665  

                   DfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyv
                   D+ H+V+T a l +   L  + ++S +d a    L +  + +     R  
  gi|1453513   666 DKSHPVMTSATLYIGNLLAHCAIRSVRDAALAVILSTMASVYSTGAERIF 715  

                   PeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfa
                   Pe  + +   ++  +  K        t  + e+   ++            
  gi|1453513   716 PEALTLMNALIHCASRSKTNWAAGLSTH-LVEQV-GGPWLS--------- 754  

                   vkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeive
                       + +ep++L+  ++      e +    l +  L    +l+ +   + 
  gi|1453513   755 SALTSAMEPMTLP--EMLDGIYAEKLEEKKLSAATLRA--ALSCLRQLSK 800  

                   iyyklqAFiEIflPIlaLLsry..slkeslpekRlkeklldavelveKlt
                      k  +  EI+ P+ +   ++++slk+s       e     v+ + +  
  gi|1453513   801 PVIKTASASEILSPVRDSVKALrkSLKKSNGGL--AELCDELVKELDDAL 848  

                   edakkerKPLAlqeHKPvaIrllePKFEE.nyDDKRsPdksSyDpDkeRs
                       + + PLA   +   aI + +P +EE++y      + + yDp +eR+
  gi|1453513   849 V--GAVKTPLAYHTKTAEAIKTFNPMYEEdGY----QKGRD-YDPNRERA 891  

                   elnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkiv
                   e  KLk++ K E +GA+RElRKD +F+a  R kE+ +   er +  k i 
  gi|1453513   892 EARKLKKQVKQETRGAMRELRKDNRFMADARSKEQFQAAEERGARQKDIL 941  

                   nelqeqegAl<-*
                    +l  qe  +   
  gi|1453513   942 SFLEKQEADF    951  

gi|116059907|emb|CAL55966.1|: domain 1 of 1, from 2 to 930: score 265.3, E = 1.4e-76
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                          + +K           NP      krKF  +   Kt       +
  gi|1160599     2    AKKKKHAK----------ANP--GSGGKRKFFQGAT-KTETETKSAF 35   

                   PGVS.RakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                    +VS R  a+ekR+rTl  e +   K + f+D+R+GE ++ Ls     E+
  gi|1160599    36 ESVSvRKNAIEKRRRTLLREHEENGKANSFVDRRFGESDDGLS----AED 81   

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsle
                   K + R    r+ Q +    +  n++  l+D+ edG  +g+        l+
  gi|1160599    82 KHIGRLAKARLRQYK----KSKNFS--LNDDDEDG--FGT--------LT 115  

                   elgeeLsdddELa........deaLDkdflalkrFeeeD...........
                   +lg+ L ++d+ a++++++++d+ LD   + + +F++ D +++ ++++++
  gi|1160599   116 HLGQPLAEGDLTAkpngddddDDNLDGEMTRAFHFGGGDfeptlkrdgng 165  

                   .AeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeN
                   ++  e e+r   K+KkEVmeE IaKSK+ KaE++K++e      dkLD+ 
  gi|1160599   166 hDVSEPERR---KTKKEVMEELIAKSKFHKAEKQKQREDDQYTLDKLDAD 212  

                   fkdLlsllamekltsRKsG..iKkpreakedt....DaeYDlllkEMvfe
                   fk ++s   m + + RK+ +++K    ak++ ++++ +eYD   + +  e
  gi|1160599   213 FK-VISQGGMLSSALRKAVghMKPTTKAKSNApeqeKDEYDTWARTLAYE 261  

                   kRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee...teEledgE...
                    R++  +R  T EE  ++E+  L+  E  RlkRM++ +++ E +d ++++
  gi|1160599   262 RRGQAGERARTQEEVEAQEKLALEQAERKRLKRMRGvnsDDESSDDDgpq 311  

                   ............eEiGGEESvkklkvr..SvdDLdDsfsVE.....EDKP
                   ++   ++++ +++E G ++ v+   vr++++dDLd  f  ++ ++ ED  
  gi|1160599   312 ggyaarrrkakkAERGDDDDVATDDVRreGGDDLDENFALDsaeevEDEE 361  

                   KfGfiedlleREDNv.dNeEddEdddeeae.......dsdDddsvndGtd
                     G +    e ED v+d  E d+d d+ a  +++ ++++ D +   d + 
  gi|1160599   362 EDGVGS---EDEDDVsDEDEADDDMDDNARlrksfrsELKDVEEDLDKGK 408  

                   lkqkKeavLkd...............dEneDDdLGAELEDkeGeeDdEeD
                    + +K   L+d+ + +++++++++ +dE+eDD       D+e e++d eD
  gi|1160599   409 NRLRKLGILQDgveakdseedeedyeDEDEDDK------DTEDEDEDDED 452  

                   edEESDaEld.....vlkdLKed...eaqplkgeai..kasvkeKANmKK
                      E D  +++++ +vl++L e+  + a++  g+++++k +    A   K
  gi|1160599   453 AEDE-DDVVEndhagVLRELEEEiagNAASREGKNPdkKETPRHEA---K 498  

                   sadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahh
                   s++     +  +ipFt+++P ++e+l   l  +  eD  +I++RI+ ++ 
  gi|1160599   499 SSES----MRVDIPFTFPMPESYEDLAGMLGAHGAEDTFTIISRIRACNA 544  

                   pKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLvea
                   p L++eN ++++  +   LLq   ++f   + Q+ +     + L  L  +
  gi|1160599   545 PTLAAEN-RKRIQTLFGLLLQRF-EIF---AGQAPIP---TDHLDVLSTH 586  

                   LielaqelPeklaislseellevikelaeeykknEhikyPSlkdLvfFkL
                      l+ + P ++a     +++++ ++l  + +   +  +P   + ++++L
  gi|1160599   587 IVDLSAQVPFFAATAVKARVEKMSSRLRQALRSG-ETGWPPSRTVLLLSL 635  

                   vgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkf
                    + +F+T D+ H+V++P+ l +   L  + ++S kd a    +++  + +
  gi|1160599   636 FAAIFPTTDKVHPVMSPVSLYLGNLLAHCAIRSTKDAALAVIIATMSSMY 685  

                   qsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekG
                    s S R  Pe v  ++  ++  + pK        t  + e++  ++    
  gi|1160599   686 SSASERVFPEAVALMSALVLSASRPKAHWSDGLPTH-LAEQI-GGPWLS- 732  

                   LPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvl
                       ++   k  tl  p +L              +  +l  + L    +l
  gi|1160599   733 ---SAINSSKSGTLSLPETLNGIY------FGKVSDELLAVVTLRA--AL 771  

                   eLvEeiveiyyklqAFiEIflP....IlaLLsryslkeslpekRlkekll
                   + +   +    k  +  EI+lP ++++ +L  ++ +  + p+    +  +
  gi|1160599   772 SCLRQLSRPVAKTASASEILLPvrssVVTLRKALKN-AKSPSA---KLCE 817  

                   davelveKltedakkerKPLAlqeHKPvaIrllePKFEE.nyDDKRsPdk
                   d  + + ++       + PLA   +   aI + +P +EE++y      + 
  gi|1160599   818 DFMKELDDSLS--GSVKTPLAYHTKAAEAIKTYNPMYEEdGY----QKGR 861  

                   sSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdq
                   + yDp +eR+e  KLk++lK E++GA+RElRKD +F+a  R+kE+a+   
  gi|1160599   862 D-YDPNRERAEARKLKKQLKQEARGAMRELRKDNRFMADARAKEQAQAAE 910  

                   erhEKmkkivnelqeqegAl<-*
                   er +  + +  +l  qe  +   
  gi|1160599   911 ERGARQRDVLSFLEKQESDF    930  

gi|281200779|gb|EFA74997.1|: domain 1 of 1, from 24 to 951: score 260.1, E = 5.4e-75
                   *->keedreeKKKAvakiqkef..NPFdvkvakrKFdilGrsKtkvKgee
                      k+  ++      + + ++   NPFd+k ++ K  +lG+   kv g+ 
  gi|2812007    24    KPQQQQQQ----QHTPSVKivNPFDRKTNRVKHSVLGK---KVVGTS 63   

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                   G  G SR   +e+Rk+Tl  e+ ++ Ks+ f+D Ri E+++  s    eE
  gi|2812007    64 GNRGQSRYNDIERRKKTLLVELNQSKKSNQFLDQRIAENDPTMS----EE 109  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                   +KMl+R++ E+       K+++ynln    D+ +    gg      l   
  gi|2812007   110 DKMLARYQKEK------MKKNLYNLN----DDDDQLIQGG------LGDH 143  

                   eelgeeLsdddELadeaLDkdflalkrFe...eeDAeaeeeqrGAkKsKk
                   +  +   ++ddEL  e+    ++  +r ++  e D e  e ++  kK+  
  gi|2812007   144 LADDYVADEDDELREEE----RMSGGRRRniyEQDEERDENGEPIKKTRE 189  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLl..sllam....
                   EV  EiI KSK ++aEraKeK  +eD + +LD  f  + ++s l+m++++
  gi|2812007   190 EVFQEIIEKSKAGRAERAKEKMLKEDITRELDQEFDEIRsgSMLMMrgkd 239  

                   ...........ekltsRKsGiK..............kpreakedtDaeYD
                   ++  +  ++++e  + R+   K++++++++++++++k+++a  + D+  D
  gi|2812007   240 dpllslfptseEEQK-RQQQQKekennkdqqqkekeKQQPAQQNEDD-FD 287  

                   lllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEle
                    l+ EM  e RA+ +dRTKT+EE  ++E+e+L +LEe RlkRM++ +  e
  gi|2812007   288 NLVLEMANEARAKATDRTKTPEEVMKEEKERLDKLEENRLKRMRGEIV-E 336  

                   dgEeEiGGEESvkklkvr..................SvdDLdDsfsVEED
                   + +e      S kk +  ++++++ ++++++ ++++ +dDL D +    D
  gi|2812007   337 EDDE------SAKKMTRYekrqkklkkdktnlpsrpTADDLND-DDFALD 379  

                   KP...KfGfiedlleREDNvdNeEd..dEdddeeaedsdDddsvndGtdl
                    P ++K   + d  e   N + eEd++dEd+dee+ed d dd + +    
  gi|2812007   380 DPlgnKDAPWYDFKE---NGEGEEDgeDEDEDEESEDGDQDDDEEL---- 422  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                                eDDd     ED+eG e++E D+dEE            
  gi|2812007   423 -----------DGEDDD-----EDEEGVEEEEDDDDEE-----------S 445  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                   ede  ++  + i a+   K N  K a+         ipFt+d Pk+ +el
  gi|2812007   446 EDEDDIEA-SRIEAE-IRKINSQKKASE-------EIPFTFDVPKSIDEL 486  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                    + l +   e k lI  RI+ ++h+ Lk+ N Kek+     vL +   +L
  gi|2812007   487 NQWLAGRTQEEKNLIYTRIRVCNHVSLKPQN-KEKMKVYLPVLWRRF-EL 534  

                   fEDlseQdikknLNfqL.......LekLveaLielaqelPeklaislsee
                      +++ +   n   ++++ +  +L  L ++ +e  +  P  la  +   
  gi|2812007   535 I--AANNNNNNNAEKDSssldwleLDLLAKYIFEVGKDVPDILAATALAM 582  

                   llevikelaeeykknEhi................kyPSlkdLvfFkLvgl
                        k+  +++ k        +++ +++++  + +PS++ L+  kL+++
  gi|2812007   583 MHSCYKRCLARIEKV-TVaaaannnatttttvvsAWPSVSELLTMKLIAN 631  

                   lFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsi
                    F+TSDf H VvTP    ma++L + p+ +  dI    fL +i+  +   
  gi|2812007   632 VFPTSDFQHQVVTPTTVAMAHFLIQLPIITPHDILSSIFLSNIFKYYLVS 681  

                   SkRyvPeVvyalqqiLftllvpKR....................DVells
                     +y Pe+   +   L  +   +++   + + ++++++++++    +   
  gi|2812007   682 ANKYSPEITSVVISLLSSFASQQKtaaatataqtktnkdsdqwaSFNTGI 731  

                   itPLtFerdRLDslekGLPldnlfavkest......llepqrLslaDLVt
                   ++P    +d+   +     +  l+ v++ t+ + + l++  +++      
  gi|2812007   732 LVPNMMLKDKCLAFAN---KKTLKKVTPATqfdfnyLIKSKQEQSQK--- 775  

                   qtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLL
                        +f +d++r  lL     l+ vE  v    +    +   lP    L
  gi|2812007   776 -----YFGTDQFRIDLLYL--LLNFVESYVKQMILSE--NTESLP--SVL 814  

                   sryslkeslpekRl.keklldavelveKltedakk....erKPLAlqeHK
                   ++  ++   +   l  + l d+++lv +l+ +  k+  ++r PL l   K
  gi|2812007   815 QLFLNQLNQFDSQLfNQVLQDKLKLVKDLIGEKNKsiveKRVPLTLLVGK 864  

                   PvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   Pv   +  P F   y        +  DpD  R e  KLka +K+E KGAi
  gi|2812007   865 PVEKKTFTPSFSKEY----HEHGD--DPDVVRQEARKLKALHKKEMKGAI 908  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   REl KD  F++ ++ k++ a+ qe   K kki  el  ++++    
  gi|2812007   909 RELIKDNNFIQQEKTKQRMAERQEIEIKRKKIMSELEQEQHEH    951  

gi|242019819|ref|XP_002430356.1|: domain 1 of 1, from 8 to 787: score 254.1, E = 3.3e-73
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k  d  +K      i+k  NPF+++ +++KFd   +           
  gi|2420198     8    KFKDAGSK----PQIKKM-NPFEIHTNRKKFD---K----------- 35   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                            s        
  gi|2420198    36 -----------------------------------------S-------- 36   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                                       ynl     D+ee+++ g++     l ++e+
  gi|2420198    37 -------------------IYNLG----DDEELTHKGQT-----LSEIEK 58   

                   lgeeLsdddELadea..LDkdflalkrFeeeDAeaeeeqrGAkKsKkEVm
                    ++  sddd  +de+++L+  f   ++F++      +      Ks k  +
  gi|2420198    59 FDDPKSDDDDDNDEEgrLESNFVENAHFGGGIFKKIDNEP---KSRKDLI 105  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                   +  I +S  +KaE++K K    D ++kLD   k Ll+l+   k+t     
  gi|2420198   106 DQLISESIKRKAEKQKLKQHTLDMTEKLDSDWKELLPLVTENKKT----- 150  

                   iKkpreakedtDae...YDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                    K   e+ +  D++  +YD l k + fe R++PsdR+K eEE+A++E+ek
  gi|2420198   151 -KSDPEPDTKKDDKfasYDVLSKKLKFEARGKPSDRLKSEEEIAKEEKEK 199  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   L++LE eR++RM + +      e        k  k+rS+dD dD      
  gi|2420198   200 LEKLEKERIQRMHGEIV-----E--------KTIKHRSADDMDD------ 230  

                   DKPKfGfiedlleREDNv..dNeE......ddEdddeeaedsdDddsvnd
                        Gf +d +  E      N+E ++++++ +  d e+ d+ Dd  +  
  gi|2420198   231 -----GFLLDNEN-ESTLayKNGElntennSENSSDNESVDLNDDGNEEV 274  

                   GtdlkqkKeav..............LkddEneDDdLGAELEDkeGee...
                     d k  K+ v+++ ++++++++++ ++  n DDd   E +D+ G ++++
  gi|2420198   275 TLDTKKNKDKVsndvpsqegndnnrIEEGGNNDDD---EDDDEDGDDnsn 321  

                   ...DdEeDedEESDaEldvlkdLKedeaqplkgeaikasvk..eKANmKK
                    ++DdE D+dE      d ++dL+e+  ++ k++ i  + k+++K   K 
  gi|2420198   322 antDDEDDDDEN-----DSYSDLRESDNESIKEKEIPLT-KdnKKG--KQ 363  

                   sadTiPASL....................drsipFtidcPktheelleLl
                    ++  P  L  + ++++++ + + ++++    ipFt+d P+ +e++  Ll
  gi|2420198   364 NSESTPNNLyvplgekddninchlessniTVEIPFTFDIPTEYEDFEKLL 413  

                   kkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDl
                   k  dl  + lI+eR ik++hp Lk +  K +l  +   LLqhI     D+
  gi|2420198   414 KSYDLNYHSLIIERMIKCNHPGLKSDH-KVNLDLLFTYLLQHI----QDF 458  

                   seQdikknLNfqLLekLveaLielaqelPeklaislseellevikelaee
                   +  d++k   f LL+ L +  + l+q +P        + l +vike+++ 
  gi|2420198   459 ASDDSIKMNSFKLLNLLAPWFFDLTQWNPQS----CASSLIDVIKEKYKD 504  

                   ykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrsp
                   + kn  ++yPSl++Lvf+kL ++lF+TSDfrH+V+TP+l +m + L +++
  gi|2420198   505 FQKN-PKCYPSLDTLVFLKLASILFPTSDFRHPVITPCLAFMEQILFQCK 553  

                   vsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVe
                   +sS  d++ GlfL +++L++ s SkR+ Pe v++l   L  l  +    +
  gi|2420198   554 ISSSIDVSTGLFLSTLILEYCSFSKRFAPEAVNFLYNVLR-LAHE-SAAN 601  

                   llsitPLtFerdRLDslekGLPldnlfavkestllepq.rLslaDLVtqt
                   +    P     +   s e      nl      + +++ ++Ls  DL+   
  gi|2420198   602 FPIRLP---LEP--KSMEY----FNLILSDKTSEVKINsQLSIQDLINTN 642  

                   iteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsr
                    + ef+  al    L i     L+ e+ + +   q       P   L   
  gi|2420198   643 SSDEFKLNALS---LGI----KLLSEFCDNWERGQ-------PAYLLFEE 678  

                   y.slkeslpek.RlkeklldavelveKltedakkerKPLAlqeHKPvaIr
                     +l  s + ++ lk  +++++e++  +      + K LAl +++P+ +r
  gi|2420198   679 FvPLLNSKLYHgCLKDAIENVLEKILNFKR---ENLKMLALEKKRPKPLR 725  

                   llePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRK
                   l eP  EE+     s +k      k ++e++KL++k KrE KGA RE+R+
  gi|2420198   726 LYEPNIEEVH----SFKKY-RPMGKKKAERAKLLHKYKREMKGALREIRR 770  

                   DakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   D +F + l+  E+ ++                     +   
  gi|2420198   771 DRSFLSKLKFRETVKS---------------------F    787  

gi|66806907|ref|XP_637176.1|: domain 1 of 1, from 5 to 970: score 251.6, E = 2e-72
                   *->keedreeKKKAv....akiqkef......NPFdvkvakrKFdilGrs
                      k+e + +KK  ++++  ki k  +  +  NPFd+kv+k K  +l r 
  gi|6680690     5    KSESVNSKKGGIsngfNKIEKSTpvvkivNPFDRKVNKTKHVVLNR- 50   

                   KtkvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkh
                      vKg+ G  G SR  a+ekRk+T+  e  + nKs+ fiD RiGE++  
  gi|6680690    51 --QVKGASGDLGQSRYNAIEKRKKTILVEMNQMNKSNKFIDARIGENDAS 98   

                   LsGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsS
                    s    eE+KMl+Rf+RE+   lr  ++++ynln   +D ee++++g+s 
  gi|6680690    99 MS----EEDKMLARFQREK---LR--NKNLYNLN--DNDQEELTHMGQS- 136  

                   vKDDl.DsleelgeeLsd........ddELadeaLDkdfla.lkrFeeeD
                       l+ sl     +Ls+++++   +ddEL+     k fl +  rF++ D
  gi|6680690   137 ----LgNSLGSNSMSLSEgnddyvasDDELDEVG--KEFLSeRQRFGGGD 180  

                   Ae...aeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLD
                   + ++++ e+q   +KsKkE+  EiI KSK +KaEraKeK ++e l+  LD
  gi|6680690   181 DDsngNGERQD-RHKSKKEIYQEIIEKSKIGKAERAKEKLKKEALTRDLD 229  

                   eNfkdLlsllame..............................kltsRKs
                   e f ++  +l  +++++++++++++ +++   + + +++++++k +s  s
  gi|6680690   230 EEFNLIRGELILTngnnsnssnnnnlqddaflkfqaeqrsneqKFASSSS 279  

                   ......GiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   ++++++  Kkp ea  d D     ll E++ e RA+ +dRTKT EE  ++
  gi|6680690   280 snstndSTKKPKEAHDDFDE----LLYELQGESRAHATDRTKTKEEQMKE 325  

                   EaekLreLEeeRlkRMee.teEledgEeEiGGEESvk.............
                   E e+L   E eRl+R  +++ Ele+ +      +S k+ +++  ++ + +
  gi|6680690   326 EMERLQQKEKERLERASGdYVELEADDN---VKDSDKnlprkvldrlkak 372  

                   ..klkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddee
                   ++k+k   +d LdD   V         i ++     N     dd+  +  
  gi|6680690   373 dnKPKMLTADSLDDENEV-------LNINGVDTVFYNPQIDSDDDNNNKD 415  

                   aedsdDddsvndGtdlkqkKeavLk.ddEneDDdLGAELEDkeGeeDdEe
                     ds+D d  n            L++ddE+  D+      D+eGee dEe
  gi|6680690   416 NSDSED-DQTNE-------QSSELEtDDEDKSDE------DEEGEEGDEE 451  

                   DedEESDaEldvlkdLKedeaqp.....lkgeaikasvkeKANmKKsadT
                   D+d            LK+de  +++++++ +e  k + k K+  KKs + 
  gi|6680690   452 DSDLD----------LKDDEILSgqeddEEEEEEKSTKKLKT-NKKSKEE 490  

                   iPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLk
                       ++  ipFt+d Pk+ eel e l     e k +I  RI  ++h+ +k
  gi|6680690   491 ----VNETIPFTFDTPKSIEELDEWLLNRTSEEKETILTRIGVCNHVSIK 536  

                   eeNRKeklvKFsvvLLqhIKDLfEDlse......QdikknLNfqL..Lek
                   + N K k+     +L q    +    +++ ++++Qd  +n  ++  +L  
  gi|6680690   537 PQN-KDKMKDYLPILYQRF--IN--IAKpikeddQDESSN-PIDWieLDV 580  

                   LveaLielaqelPeklais...lseellevikelaeeykknEhikyPSlk
                   L ++ +e++q  P   +i +++l++ + + i ++ e   k     +P   
  gi|6680690   581 LSKYIFEISQDVPIVSGITskdLINSCYKRICKKLEIQSKL--NYWPNQQ 628  

                   dLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfL
                    L+  kL+g+ F+TSDf H+VvTP +  +  +Ls +p++   dI   lf 
  gi|6680690   629 ELLVIKLIGNVFPTSDFQHPVVTPTIEALNFFLSHCPIRNANDIISSLFT 678  

                   vsiVLkfqsiSkRyvPeVvyalqqiLftllvpK.................
                    ++   + s SkRy Pe+   l   L t++   +++ +++++++++++++
  gi|6680690   679 MNLLFFYLSPSKRYSPEISSLLISLLSTFINHNpptiqtttttttkpkns 728  

                   .....................RDVellsitPLtFerdRLDslekGLPldn
                   +++++++ ++++++++ +++   +  + + P t  ++ L  l++     n
  gi|6680690   729 knsktttatttttpsninsqwASISTNILIP-TILLP-LNYLKL-SNQIN 775  

                   lfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEe
                   +  + e t le  +Ls         +e    d lr  +L+    ++ +E 
  gi|6680690   776 VIKKIEPTQLEFSNLSKSN------LEI--NDELRINILNY--LISFLEK 815  

                   iveiyyklqAFiE....IflPIlaLLsryslkeslpekRlkeklldavel
                    +  y   q F+E+ ++ f  Il LL ++     +  k l ek+ +  +l
  gi|6680690   816 YIRFYSESQ-FNEslpsLFTNILNLLNKLDT-NTMNLK-LIEKINSLKQL 862  

                   veKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpD
                   +     +   +rKPL l   KP  +r  +P+F  ++    s   +  DpD
  gi|6680690   863 IDSINKEIINKRKPLILLTSKPQTLRQFNPRFNQVF----SFFNK--DPD 906  

                   keRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKm
                    eR   +K+ka +K+E KGA RE+ KD +F++ ++ k    + +e   K 
  gi|6680690   907 AERNHTAKMKALIKKETKGALREIVKDNQFIQAEKFKKATEERKENEKKR 956  

                   kkivnelqeqegAl<-*
                   k i  elq ++ +    
  gi|6680690   957 KQIMSELQSEQQEH    970  

gi|114592954|ref|XP_001151429.1|: domain 1 of 1, from 19 to 675: score 250.1, E = 5.3e-72
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +     +K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1145929    19    GARGGPAK--------ANSNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k + Ks++f DkR+GE n   s     EeK
  gi|1145929    55 PGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1145929   101 MMKRFALEQ--QRHHEKKSIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFeeeD........AeaeeeqrGAk
                     +  + d+d ++   L + ++a+ +F++ ++  +++++ e+ee+ +   
  gi|1145929   140 HNDIVDSDsDAEDRGTLSAELTAA-HFGGGGgllhkktqQEGEEREK--P 186  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                   Ks kE +eE IaKSK  K Er++++e    l++kLD   k ++ ll+   
  gi|1145929   187 KSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--H 234  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                   +t  Ks   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++
  gi|1145929   235 KT-PKSENRDKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKE 281  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   E e+Lr+LE eRl+RM +  E    +e       vkk+k+ S+dDL D f
  gi|1145929   282 EQERLRKLEAERLRRMLGKDE----DE------NVKKPKHMSADDLNDGF 321  

                   sVE.EDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtd
                     +++D+    + ++    E+ v  e + E  d e+ ++++    ++G+ 
  gi|1145929   322 VLDkDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG- 367  

                   lkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdL
                            +d E++D        D      d e  +E+   E ++ k  
  gi|1145929   368 ---------EDTEESDSP------DSH---SDLESNVES---EEENEKPA 396  

                   KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthee
                   Ke    p kg    +s+ke A   K            +p+t+  P ++ee
  gi|1145929   397 KEQRQTPGKGL---ISGKERA--GKATRD-------ELPYTFAAPESYEE 434  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   l  Ll + + e   l+VeRI k++hp L+e+N K kl+K+  +LL ++  
  gi|1145929   435 LRSLLLGRSMEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV-- 481  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                      Dl+  d      +    kLv +L+ l q +Pe +      +l++   
  gi|1145929   482 --GDLATDDPPD---LRVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMH 526  

                   elaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaev
                   e+ e +        P l+ L+++k++gllF+TSDf H+VvTPal  +++ 
  gi|1145929   527 EMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQL 576  

                   LsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvp
                   L ++p+ Sl+d+ +Glf + ++L+++  S R++Pe++++l +iL+   + 
  gi|1145929   577 LTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY---IA 623  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDL
                            tP                    +a + stl+ p r      
  gi|1145929   624 ---------TP-----N--------------KASQGSTLVHPFRALGKN- 644  

                   VtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIla
                                  s lL +        e v  +   +           
  gi|1145929   645 ---------------SELLVV-----SAREDVATWQQSS----------- 663  

                   LLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPva
                       +sl     ++                                    
  gi|1145929   664 ----LSL---RWSR------------------------------------ 670  

                   IrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiREl
                                    Pd                               
  gi|1145929   671 ----------------IPDLR----------------------------- 675  

                   RKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                              
  gi|1145929     - ----------------------------------------    -    

gi|119113792|ref|XP_310703.3|: domain 1 of 1, from 20 to 818: score 238.3, E = 1.9e-68
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k +++    KA a ++k  NPF+  v k K  +l r      g+  k
  gi|1191137    20    KADAVLRR-KAAATVRKP-NPFETVVMKTKHAVLNR------GTQSK 58   

                   .PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                   +PG       ekR +Tl++ef+  +K++ f D R        +       
  gi|1191137    59 rPGQLHRLSHEKREQTLGKEFALLHKTNQFMDARQN------G------- 95   

                   KMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsle
                       R+ R+    ++   +e+ynln      +++G r          ++e
  gi|1191137    96 ----RYARQP--SRKEQAKEMYNLN------LTHGGRTM-------HEIE 126  

                   elge..eLsdddELadeaLDkdflalkrFee..eDAeaeeeqrGAkKsKk
                   +l++ ++  d+dE  d  L   f+ + +F+++++D+++   ++  +K+  
  gi|1191137   127 HLDDvpDGADEDEDEDGMLQDAFTSATHFGGgsDDDSGRPAGK-DRKT-- 173  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                    V+eE+Ia+SK+ K Er+ e +e++  +  LD+  k+L++    e     
  gi|1191137   174 -VIEEMIAESKRQKTERQRENDEMYEMRLRLDDELKSLMPQFT-EHIR-- 219  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                          r+ + +  + YD  l+EMvfe+R++P++++K  +  A++E  +
  gi|1191137   220 -------RDSERPKPDDYDRALREMVFEPRGAPTEKLKSID-RAAEEQKR 261  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                    +  E e  +RM+  e                ++  +S+d L+D + VE 
  gi|1191137   262 REVAEREKQQRMQQQEAQRVTQG-------ASRP--ISADALGDDYLVEG 302  

                   DKPKfGfiedlleREDNvdNeEd.dEdddeeaedsdDddsvndGtdlkqk
                   +     ++   +   D v N+  +dE + ee  +++Dd+++ +       
  gi|1191137   303 EGQEEAYYG--EPDGDDVRNGSApDEEEEEEEDEEEDDEGEES------- 343  

                   KeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKede
                          d  e D     L D +  + +E D+  E               
  gi|1191137   344 -------DSSEADS----LSDLKAAVQQEDDSEDE-------------QD 369  

                   aqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleL
                   a+p+++ a k +v  KA  K  a        +    + d P+ +e + eL
  gi|1191137   370 AEPEPEPA-KQTVAPKAKAKPAAVA-----PTYTLRMVDVPREYEQFAEL 413  

                   lkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfED
                   l ++  +    +       h    k+   K++   + +  L ++   f  
  gi|1191137   414 LDGHEGDVQGRVGVVASMVHTLRQKPFLHKSRWSVLFAYALNYLGVRFAH 463  

                   lseQdikknLNfqLLekLveaLielaqelPeklaislseellevikelae
                   ++   i     f+ L  L++ L+ +aq  P+  ++ + ++l+    e++ 
  gi|1191137   464 ATSATIAGE--FEMLHLLTPLLHDIAQTDPSGIGRVFHSVLE----EKYS 507  

                   eykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrs
                    ++k     yP l + v++kLv  lFs SD rH +vTPal +  e Lsr+
  gi|1191137   508 VFRKQ-PRRYPDLATVVLLKLVPVLFSASDRRHSIVTPALVFVGEILSRC 556  

                   pvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDV
                    v+ ++dIa Gl Lv+ VL+    SkR++P  v +l + L      K   
  gi|1191137   557 QVRNRRDIARGLLLVTTVLECAEHSKRFLPSTVAFLTGVLG-QACAKDAL 605  

                   ellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqt
                     l  +  +F +    sl++    d+l +    t     +L   DL    
  gi|1191137   606 HPLATVGQPFKLT---SLQL-SEADVLTEADAAT----TQLTGQDLLLGQ 647  

                   iteefpvdalr.sSlLliKEvleLvEe....iveiyyklqAFiEIflPIl
                   +t+ f+v+a + ++ Ll+    +L+  +  +iv + ++ +          
  gi|1191137   648 LTPSFKVRAIVcTVTLLSALCTQLDSNpalpIVAAHFLIP---------- 687  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKP.LAlqeHKP
                     L+++       +  ++  l  ++  ++ l+        P LA ++ KP
  gi|1191137   688 --LHAIRQ-APSSQP-VQTALDETIAQLSALAG----RTLPyLAQAKQKP 729  

                   vaIrllePKFEEnyDD.KRsPdksSyDpDkeRselnKLkaklKrEkKGAi
                   + +rllePK   +y+D +R+P+       + R+++ KL  k+K+  +GA 
  gi|1191137   730 KPLRLLEPKINPVYEDiRRRPKTA----VPVREQRRKLQQKIKKVTRGAK 775  

                   RElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   RE+R D    a l  k +  +d er  K++ i   +++q+ +l   
  gi|1191137   776 REIRLDNEYLAKLQHKRRMESDRERQQKVRQIFSHASHQQAEL    818  

gi|167516260|ref|XP_001742471.1|: domain 1 of 1, from 19 to 854: score 237.1, E = 4.4e-68
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       ee + + +K  a   +  NPF+ +  +rK d+lG    kvKge+G 
  gi|1675162    19    QEEQVLSRRKGAATQDEAQNPFELQQQRRKHDVLGQ---KVKGERGN 62   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                       R  a+  R + l  e+ +++K ++f DkR+GE n   s    +EeK
  gi|1675162    63 KARARDAAIKSREKSLLVEYRQRHKDSRFTDKRFGEYNTGMS----VEEK 108  

                   MleRfsRErmSQlrLSKreaynlnDGlEDvee....dGdrggsSvKDDlD
                   Ml+Rf +E+    + S  +  nl+D  ED ee   ++ +r++s   + +D
  gi|1675162   109 MLARFAAEQ--RKKHSRSSVFNLDDDDEDAEEllltHNNRPLS---EAMD 153  

                   sleelgeeLsdd..dELadeaLDkdflalkrFeeeDAeaeee......qr
                   s   ++ee ++d +d  a +   +d     +F++ DA  eee++++++qr
  gi|1675162   154 SYIPSDEEMDEDaqDFGARAT-NADMVSRFHFGGGDAGDEEEqddgqpQR 202  

                   GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlslla
                     k + +E+m E+IaKSK yK Er+ ++ e eD +   D++  d+l l+ 
  gi|1675162   203 --KRTHREIMAEVIAKSKSYKHERQRQQQETEDMTNAVDDQLNDILGLVF 250  

                   mekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEEl
                    e+         + r+   + D  YD  +  +  +  A+ +dR+KT+ E 
  gi|1675162   251 GESNR----AEQEGRVLAAPADSTYDTAIVQLAADNKARATDRLKTPQEE 296  

                   AqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklk...vrSvd
                   A +++e+L+ LE +R  R ++    e++        S  k  ++ v+ +d
  gi|1675162   297 AEEARERLERLEAQRQARLRGEDP-EAEQS------SNLKSSseyVGAGD 339  

                   DLdDsfsVEEDKPKfGfiedlleREDN....vdNeEddEdddeeaedsdD
                   D d+    EED    G +++ll   D + + v  +    d ++ a    +
  gi|1675162   340 DSDA----EED----GAGLELLPMGDGtaklVSKSGQAVDLNSSAKPGSG 381  

                   ddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESD
                      v d             d E +DD+     +D+e e Dd    d +  
  gi|1675162   382 ---VAD-----------DDDEEASDDE-----DDEEAELDDSDAADAS-- 410  

                   aEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFt
                             ede   ++  + + s+         +d      d  +pF 
  gi|1675162   411 ----------EDEFGLEPDFGASTSGAPEH----ESDA---EEDFEVPFV 443  

                   idcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFs
                   +++  + e++  Ll+        +  eR i +h + L++ N +  ++   
  gi|1675162   444 FKPVSSAEDMMTLLEAYPISKRRILLERLIACHNVHLAAAN-RAIQETHF 492  

                   vvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaisl
                    +L q +         Q i     +  Le L   L+ l  +   ++a  +
  gi|1675162   493 MALWQCV--------GQSIQQGEALSALEPLIWSLYTLMLQVKAAAATTA 534  

                   seellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvT
                   ++++ e   e+      +    +P l  L++F++v  lF+ SD  H+V T
  gi|1675162   535 RNRIFEL-HEKTRGGSWP---SFPKLRHLIYFQIVPELFPASDRWHAVAT 580  

                   PalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalq
                   Pall   + L  + v   +  a Gl+L+s    ++  S+R vPe   +l 
  gi|1675162   581 PALLAAMHLLTNCNVANMRNMAAGLYLCSCAYVYVQESHRIVPEALAFLN 630  

                   qiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestlle
                     L        +     + P  F +    + ++   +    +      l+
  gi|1675162   631 SFLQCCTAAPSEAGSRLLLP-AFSLL--KPAQR---KSLRCTPASWKGLK 674  

                   pqrLslaDLVtqtitee.fpvdalrsSlL.liKEvleLvEeiveiyyklq
                   p   +l        +e++f+  al+ + L+l+  +l+L   +   y    
  gi|1675162   675 PAAMPLER------LEAgFKGCALEQVKLdLVALALQLTHKFARLYQTHA 718  

                   AFiEIflPIlaL...LsryslkeslpekRlkeklldavelveKltedakk
                   A +E +   +a  ++L + +  + +        l da     +       
  gi|1675162   719 AMPESLACAQAAarqLEQVPCLKAICTP--LVELFDACAGMRDAVR---- 762  

                   erKPLAlqeHKPvaIrllePKFEE.nyDDKRsPdksSyDpDkeRselnKL
                          q HKPv + +leP + ++++      +k   D D +  e   L
  gi|1675162   763 ------FQAHKPVPLEMLEPDYNAhGF------GKR-SDQDQTDRENERL 799  

                   kaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqe
                   ++ l++E+KGA+RElRKDa+F + ++l      d +r+   k + ++lq 
  gi|1675162   800 RRELRKERKGAVRELRKDARFLSKVKLNDIIENDRDRNQRLKSAFATLQS 849  

                   qegAl<-*
                    +  +   
  gi|1675162   850 DQADF    854  

gi|1843399|dbj|BAA19121.1|: domain 1 of 1, from 1 to 708: score 231.7, E = 1.8e-66
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                        + + +                             s   ++g+   
  gi|1843399     1    HNDIVDSD----------------------------SDAEDRGT--- 16   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                           Ls        
  gi|1843399    17 ----------------------------------------LS-------- 18   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                         +E           a  +             gg            
  gi|1843399    19 ------AEL---------TAAHFG------------GG------------ 29   

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                          + +L                    e+ee+ +   Ks kE +eE
  gi|1843399    30 -------GGLLHKKT--------------QQEGEEREK--PKSRKELIEE 56   

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                    IaKSK  K Er++++e    l++kLD   k ++ ll+   +t  Ks   
  gi|1843399    57 LIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLS--HKT-PKSENR 103  

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++E e Lr+LE
  gi|1843399   104 DKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKEEQEHLRKLE 151  

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE.EDKPK
                    eRl+RM +  E    +e       vkk+k+ S+dDL D f  +++D+  
  gi|1843399   152 AERLRRMLGKDE----DE------NVKKPKHMSADDLNDGFVLDkDDRRL 191  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavL
                     + ++    E+ v  e + E  d e+ ++++    ++G+          
  gi|1843399   192 LSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG---------- 228  

                   kddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplk
                   +d E++D        D    + +   e EE     ++ k  Ke    p k
  gi|1843399   229 EDTEESDSP------DSH-LDLESNVESEE-----ENEKPAKEQRQTPGK 266  

                   geaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkld
                   g    +s+ke A   K            +p+t+  P ++eel  Ll + +
  gi|1843399   267 GL---ISGKERA--GKATRD-------ELPYTFAAPESYEELRSLLLGRS 304  

                   leDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQd
                    e   l+VeRI k++hp L+e+N K kl+K+  +LL ++     Dl+  d
  gi|1843399   305 MEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV----GDLATDD 349  

                   ikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykkn
                         +    kLv +L+ l q +Pe +      +l++   e+ e +   
  gi|1843399   350 PPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMHEMEEMIETK 396  

                   EhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSl
                        P l+ L+++k++gllF+TSDf H+VvTPal  +++ L ++p+ Sl
  gi|1843399   397 GRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQLLTKCPILSL 446  

                   kdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsi
                   +d+ +Glf + ++L+++  S R++Pe++++l +iL+    p +      +
  gi|1843399   447 QDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY-IATPNKASQGSTL 495  

                   tPLtFerdRLDslekGLPldnlfavkestllepqrLsl...aDLVtqtit
                   +  +F     +  ++   l+++ a  ++       Lsl+    L   t t
  gi|1843399   496 VH-PFRAL--GKNSE---LLVVSAREDVATWQQSSLSLrwaSRLRAPTST 539  

                   eefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrys
                   e+   ++   S L +   l L+   v  y++l++F  I+ P +aLL    
  gi|1843399   540 EANHIRL---SCLAV--GLALLKRCVLMYGSLPSFHAIMGPLQALLTDHL 584  

                   lkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrlleP
                       + ++  ++ l    +      e+ k+   PL   + KPv + l  P
  gi|1843399   585 A---DCSH--PQELQELCQSTLTEMESQKQLCRPLTCEKSKPVPLKLFTP 629  

                   KFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakF
                   +   + +  R  + s     ke  e++ L +k+KrE KGA+RE+RKD +F
  gi|1843399   630 RLVKVLEFGRKQGSS-----KEEQERKRLIHKHKREFKGAVREIRKDNQF 674  

                   varlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    ar  l E    d er  K+k + n l +qeg+    
  gi|1843399   675 LARMQLSEIMERDAERKRKVKQLFNSLATQEGEW    708  

gi|149047413|gb|EDM00083.1|: domain 1 of 1, from 19 to 653: score 226.1, E = 9.3e-65
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +      K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1490474    19    GAFGGPGK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|1490474    55 PGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1490474   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|1490474   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ ll+    +s+
  gi|1490474   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILLS---RKSK 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +Da YD  ++E+ fe  A+Ps R KTeEElA++E ek
  gi|1490474   236 KSENKEKKE-KPQPDA-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQEK 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   Lr+LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|1490474   284 LRKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|1490474   318 -----GFILDKDD-----RRLLSYKDGKMNIEDAQEEQSKGADGQENDQK 357  

                   eavLkddEneDDdLGAELEDkeGeeDdEeD.....edEESDaEldvlkdL
                   e   +  E+  D        ++ e+ dE D++++++d ES aE +   + 
  gi|1490474   358 EEEDESEEEGEDG-------ESCEDPDESDgpdshSDLESSAETEEEDET 400  

                   .KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                   +K +  q   g+ +k     KA   K a          +p+ +  P ++e
  gi|1490474   401 pKKEQRQTPGGKSPKEA--QKA--QKAAAA-------ELPYVFAAPESFE 439  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                   el  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I 
  gi|1490474   440 ELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI- 487  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                       Dl+         +    kLv +L+ l q +Pe +    + +l++  
  gi|1490474   488 ---GDLATDSTPD---LKTIDKLVVHLYNLCQMFPESASDAIRFVLRDAM 531  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                    e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPal+ m++
  gi|1490474   532 HEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQ 581  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                    L ++pv Sl+d+ +Glf + ++L+++s S+R+vPe+ ++l +iL+   +
  gi|1490474   582 MLTKCPVTSLRDVVKGLFVCCLFLEYVSLSRRFVPELLNFLLGILY---I 628  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                             tP                                      
  gi|1490474   629 A---------TP-------------------------------------- 631  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                                                      ++k q          
  gi|1490474   632 -----------------------------------NKKSQ---------- 636  

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                                e+ l +         + +                   
  gi|1490474   637 -------------EH-LGR---------TQSCS----------------- 646  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                               +    s+ k                             
  gi|1490474   647 ------------W----SLTKQ---------------------------- 652  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                           +   
  gi|1490474   653 ----------------------------------------M    653  

gi|196009480|ref|XP_002114605.1|: domain 1 of 1, from 9 to 801: score 218.4, E = 1.9e-62
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k   r+ K          + PF+vk +k+K+ ilG    k K   ++
  gi|1960094     9    KRFSRQLK------DCPIDRPFEVKKTKNKRHILGT---KTK-NGRF 45   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                    G    k   kRk  l    +++ K++ ++D R GE +  Ls     E+K
  gi|1960094    46 AGYTNSKLALKRKDRLNTMIEQRTKRNKIVDHRLGEYDQSLS----AEDK 91   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsle.
                   M+ Rf  E+       K eay l      ++ ++++g+s     l ++e+
  gi|1960094    92 MIQRFAVEK--KKHHEKAEAYQLE-----DYQLTHLGQS-----LAEVEn 129  

                   .elgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVm
                    + +e  s d+  +++  D   l +++F     e + e            
  gi|1960094   130 fQEDEKFSSDEDNDNAQ-DDSDLYFGGFLKKKSESQSEST---------- 168  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                               Er  eKe+ e  + + De  k +++ l   +       
  gi|1960094   169 ---------NQYERKREKERTENMMLNIDEEWKEMMPVLIQSSIN----- 204  

                   iKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLre
                           e+  + YD++++E+ f+  A+ + R+K eEEl ++E+ekL+ 
  gi|1960094   205 -AANTTRQENKVDSYDKSVRELAFDLKAKATSRLKSEEELIKEEKEKLEQ 253  

                   LEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP
                   LE  Rl+RM++   l d  e        k++k+ S+d      ++EE + 
  gi|1960094   254 LEADRLRRMKG---LPDTSE--------KRPKHLSADAMET--NIEEIRD 290  

                   Kf..............Gfie.dlleR...........EDNvdNeEddEdd
                   K+   +  +++   ++G+ e++ll R++ ++ ++++  D  d + dd+d 
  gi|1960094   291 KRialrymdgkavipeGYTEeELLPRskattvddnelSDQEDVSDDDNDQ 340  

                   deeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDd
                   ++  ++s  +++                  E+eD +   E E ++ eeD 
  gi|1960094   341 NSDEAESAEEEGSEE---------------EEEDLE---EEEEIS-EEDS 371  

                   EeDedEESDaEldvlkdLKe.deaqplkgeaikasvkeKANmKKsadTiP
                     +ed  SD  +   ++  ++d a+   +   k++v+      K a    
  gi|1960094   372 DSLEDLNSDEDVNSPQESENeDSAEEMNKQEEKNTVSLEM---KAAAE-- 416  

                   ASLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkee
                         +p+ ++ P ++ e+  L+ k +l D  +I+ R ++ +h+ L   
  gi|1960094   417 -----ELPYQFKAPASYNEFKSLVTKRSLQDQLTIIDRLRTHYHISLDSK 461  

                   NRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaq
                   N + kl+ +   LL h+  +  +++eQ   +n     L  L ++ ++laq
  gi|1960094   462 N-RGKLEVLLDCLLHHLENITQEFTEQMLNSN----VLDGLIKHIFSLAQ 506  

                   elPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFs
                     P   a +    l ++ +e  ++ k      +P +  L+fF+ ++++F+
  gi|1960094   507 VSPQYTANCCLLFLNKYVNETKKKGKAA----FPGIHQLIFFRVMAIIFP 552  

                   TSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkR
                   T D  H + TP +l m   L  s v+Sl dI +Glf+++ +L ++s SkR
  gi|1960094   553 TTDYHHCISTPTMLYMGKLLIESNVESLTDITKGLFICNNILDYVSKSKR 602  

                   yvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnl
                   +vPeVv +l  i+    +             tF                 
  gi|1960094   603 FVPEVVIFLTDIIS--AFS------------TFKDR-------------- 624  

                   favkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEei
                      k  +ll + +L                   r SlL    ++ L+  +
  gi|1960094   625 ---KYENLLHIENLE------------------RLSLLAL--AIDLLDQF 651  

                   veiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKlt
                      y  + AF+EI    ++ L  +   e +p   +k + ++   +++ ++
  gi|1960094   652 AKLYANAVAFPEIYHRTSEILNCIDI-EGYPAE-IKANYESIQMKISSSI 699  

                   edakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRse
                         r  L lq++KP  + lleP+FE     + +   s       +  
  gi|1960094   700 S---EPRNYLILQKRKPQPLKLLEPRFEDRT--QTNSERS----YGNKKH 740  

                   lnKLk..aklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkki
                   l K+k++++ Kr  K   RElR+D++ va+  ++ ++  d er  K+k i
  gi|1960094   741 LEKMKdrRQNKRDQKRLTRELRRDSRYVAMKQREDRRMRDTERKRKVKEI 790  

                   vnelqeqegAl<-*
                   +  l+ q+ ++   
  gi|1960094   791 EHLLSNQQAEM    801  

gi|25143366|ref|NP_740774.1|: domain 1 of 1, from 1 to 797: score 216.5, E = 6.9e-62
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                         d++ K       q + NPF+ k++k K dilGr   k    +G 
  gi|2514336     1    MGVDKKQK-------QRKTNPFELKFNKSKHDILGR---KKGAQVGA 37   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P  SR +a e+R +Tl+ e+  knK + ++DkR GE++   s    eEeK
  gi|2514336    38 PTASRKRAHEQREQTLGVEYDRKNKISKIVDKRLGEKDGK-S----EEEK 82   

                   MleRfsRErmSQlrLSKreaynln...DGlEDveedGdrggsSvKDDlDs
                   +  Rf+ Er   ++   + a ++n ++DG E  e +++ g       l  
  gi|2514336    83 GAMRFTEER---VK-NYKRASKFNltdDGDEEEEVLTHKGKA-----LSD 123  

                   leelgeeL...sdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsK
                   +e+++ +  ++sdddE+            ++F++    aee  r  k s 
  gi|2514336   124 IEKYDKSMisdSDDDEEPGNL-GSNMVKVAHFGGGEKTAEEHVR-EKISR 171  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll.ameklt
                      ++  IaK Kl + E++ +K+e e  ++ LD  +  L+   +a  ++t
  gi|2514336   172 EDMISNLIAKTKLARHEKQQQKDELELMTESLDSKYQALMGKMkASFRPT 221  

                   sRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEa
                            ++ + d  ++  + lk    + RA P+dR   eEE A kE+
  gi|2514336   222 -------GRQPLEKDDYDKLTITLKT-EADARATPADRKLSEEEEALKEK 263  

                   ekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV
                   e+L+ LE         +   +  ++             r v      f V
  gi|2514336   264 ERLETLEAAPDADVDIDAG-SKADA-------------RKVQAKNSRFEV 299  

                   EEDKPKf....GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGt
                        Kf++++G i+     ED v+ +       +++ +sdD        
  gi|2514336   300 -----KFddegGLID-----EDTVEKSRILKKNLDGSDESDD-------- 331  

                   dlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkd
                                    D+   +LED+e e+ d  +edE          +
  gi|2514336   332 -----------------DE---DLEDEE-EDLDDLLEDED---------E 351  

                   LKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                   L ed    +  ea k    +KA  KKsa   PA     +pF +++Pk++ 
  gi|2514336   352 LEEDSDDEEAQEAQKVV--KKA--KKSAPE-PAE---TLPFVFEMPKNYK 393  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                    + +Ll+k++ e   l+ eR  k+hhp Lke+N K++l K+    L+   
  gi|2514336   394 KFCALLEKHS-ESMDLVLERLVKCHHPSLKEGN-KKRLNKLFLLCLRWFD 441  

                   DLf.EDlseQdikknLNfqLLekLveaLielaqelPeklaislseellev
                   D+ +E+l+   +k+   + L + ++ aL     +   +  + l+ +  + 
  gi|2514336   442 DMSkEELTAESVKE---MNLAQETMHALMKFDIQYGVRCVRALIRQHWKG 488  

                   ikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllma
                   +  ++++   +      S +     +Lv+ lF+  D  H+Vv Pal l  
  gi|2514336   489 RQDKQKS--SP-----VSFGLISAIRLVSGLFPVADSWHPVVVPALFLAT 531  

                   evLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftll
                   e L   +   l   a+   L++ + +++s SkRyvPe+v +   +L+ l 
  gi|2514336   532 EALCSAKCANLNALAKQIQLANAIVEYVSESKRYVPELVAFARSALL-LA 580  

                   vpKRDVellsi..........tPLtFerdRLDslekGLPldnlfavkest
                   v      ++s++  +++ + ++P   e      +e+   +   +a ++++
  gi|2514336   581 VT-----EKSEkfatngfpisKP-HTEML---CFEE---KYTGPALQPIS 618  

                   llepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyykl
                   l  + + s+ D       + ++   lr+ l li         +  + y+ 
  gi|2514336   619 LTTIFNNSPSD-------PSLKLHVLRALLSLI--------QHLRVIYSN 653  

                   qAFiE....IflPIlaLLsryslkeslpekRlkeklldavelveKlteda
                   q  +E+ + +f P+l  L  +   + lp   ++e l+         +  a
  gi|2514336   654 Q--NEtysiVFKPFLRILESIQA-KNLPAE-VQEELETLCASMKAEIG-A 698  

                   kkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRselnK
                   k     L+l +     + +leP+FE  + D  +P          + e +K
  gi|2514336   699 KCRLVHLSLVKTEKSMLKMLEPRFEWDF-DPERPHHG------PKDEKKK 741  

                   LkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelq
                   L + l+ E++GAi+ElRKD+ F ar  l     kd +r +  k++   l 
  gi|2514336   742 LTKNLRNERRGAIKELRKDTAFLARKQLSSVKTKDRARIAATKRVMGGLM 791  

                   eqegAl<-*
                    q+g+    
  gi|2514336   792 QQQGEW    797  

gi|268563498|ref|XP_002638852.1|: domain 1 of 1, from 1 to 790: score 207.3, E = 4.1e-59
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                             K       qk+ NPF+ k++k K+dilGr   k    +G 
  gi|2685634     1    ------QK-------QKKINPFELKFNKSKYDILGR---KKGAQVGA 31   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   P  SR +a e+R +Tl+ ef  knK + ++DkR GEr++  +    eEeK
  gi|2685634    32 PTASRKRAHEQREKTLGVEFDRKNKISKIVDKRLGERDDK-T----EEEK 76   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveed.....GdrggsSvKDDl
                   +  Rf+ Er   ++   + a ++n  l D+ + ++ + ++ g s     l
  gi|2685634    77 GAMRFTEER---VK-NYKRASKFN--LADDQDEeevtiTHKGKS-----L 115  

                   DsleelgeeL...sdddE....LadeaLDkdflalkrFeeeDAeaeeeqr
                     +e+++ +  ++sdddE++++L +    ++  ++++ e    e  +e+ 
  gi|2685634   116 SDIEKYDKSMisdSDDDEepgnLGSQM--VRIAHFGGGEKTAEEMVKEKI 163  

                   GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll.
                       s    ++  IaK Kl + E++ +K+e e  ++ LD  +  L+   +
  gi|2685634   164 ----SREDMISNLIAKTKLARHEKQQQKDELELMTESLDSKYAALMAKMk 209  

                   amekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEE
                   +  ++t         +  + d  ++  + lk    + RA P+dR   eEE
  gi|2685634   210 SSFRPT-------GRQQLEKDDYDRLAITLKT-EADARATPADRKLSEEE 251  

                   lAqkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDL
                    A kE+e+L  LE        +   + d ++        +k   r     
  gi|2685634   252 EALKEKERLDSLE-------AAPDADVDVDA-------GAKADSRKLKAK 287  

                   dDsfsVEEDKPKf....GfiedlleRE.......DNvdNeEddE.dddee
                    + f V     Kf++++G i++  eR +  ++++D  + eEddE dd ee
  gi|2685634   288 NARFEV-----KFddegGLIDGDVERSrilktsgDSDEEEEDDElDDEEE 332  

                   aedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeD
                    ed+dD     +                         +ED+e  eD EeD
  gi|2685634   333 EEDLDD-----L-------------------------MEDEEELEDSEED 352  

                   edEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLd
                   e EE                    + ++k         KKs +T    + 
  gi|2685634   353 EEEE--------------------EAGVKKG-------KKSKET----VA 371  

                   rsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKe
                   +++pF +++Pk++  + +Ll+k++ e   l+ eR  k+hhp Lke+N K+
  gi|2685634   372 TDLPFVFEMPKNYKKFCALLEKHA-ESMDLVLERLVKCHHPSLKEGN-KK 419  

                   klvKFsvvLLqhIKDLf.EDlseQdikknLNfqLLekLveaLielaqelP
                   +l K     L+   D+ +E+ + Q +k+   + L + ++  L     +  
  gi|2685634   420 RLNKMFLMVLRWFDDMAkEEVTMQSVKE---MNLAQATMFSLMKFDIQYG 466  

                   eklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSD
                    +  + l+ +  + + e+ +  k +      S +     +Lv+ lF+  D
  gi|2685634   467 VRCVRALIRQHWKGRQEKEA--KSP-----ASFGLISAIRLVSGLFPVAD 509  

                   frHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvP
                   + H+Vv Pa+ l  e L   ++  l   a    L++ + +++  SkRyvP
  gi|2685634   510 QWHPVVVPAFFLATEALCSAKIPNLGVLARQIQLANAIVEYVAESKRYVP 559  

                   eVvyalqqiLftllvpKRDVellsitPLtFerdRLD.....slekGLP..
                   e+v +   +L+ l v         ++P  F     + + + + ++ L  +
  gi|2685634   560 ELVAFARSALL-LAVT--------EKPEKFSTN--GfpisaPHSEMLCvr 598  

                   .ldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvle
                   ++  + a ++++l  + ++ l D      ++ ++   lr+ l li     
  gi|2685634   599 eKITDAALQPISLGSIFNETLPD------SPSLKITVLRALLSLI----- 637  

                   LvEeiveiyyklqAFiE....IflPIlaLLsryslkeslpekRlkeklld
                       +  + y +q  +E+ + +f P+l  L ++   e lp   ++e l+ 
  gi|2685634   638 ---QHLRVMYTAQ--NEtyniVFEPFLKTLNAIQT-ENLPKE-VQEELET 680  

                   avelveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksS
                    +      +  ak+    L+l +     + +leP+FE  + D  +P k  
  gi|2685634   681 LIASMKAEIG-AKRRLVHLSLVKTEKSMLKMLEPRFEWDF-DPERPHKG- 727  

                   yDpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqer
                         + + +KL + l+ E +GAi+ElRKD+ F ar  +     kd +r
  gi|2685634   728 -----PKDDKKKLVKNLRNEQRGAIKELRKDTAFLARKQMSNVKSKDRAR 772  

                   hEKmkkivnelqeqegAl<-*
                    +  k++   l  q+g+    
  gi|2685634   773 IAATKRVMGGLMQQQGEW    790  

gi|157822351|ref|NP_001099483.1|: domain 1 of 1, from 19 to 639: score 204.3, E = 3.3e-58
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      +      K           NPF+vkv++ KF ilGr   k ++++G 
  gi|1578223    19    GAFGGPGK--------TNPNPFEVKVNRQKFQILGR---KTRHDVGL 54   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PGVSRa+a+ kR +Tl +e+k +nKs++f DkR+GE n   s     EeK
  gi|1578223    55 PGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSNIS----PEEK 100  

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   M+ Rf  E+  Q+   K++ ynln     +ee+++ g+s     l  +e+
  gi|1578223   101 MMKRFALEQ--QRYHEKKNIYNLN----EDEELTHYGQS-----LADIEK 139  

                   lgeeLsdd.dELadeaLDkdflalkrFee..eDAeaeeeqr.GAk.KsKk
                     +  + d+d ++  aL + ++a+ +F+++    + ++e+++G k+K+ k
  gi|1578223   140 HNDIVDSDsDTEDRGALSAELTAS-HFGGgvHKNSSQKEGEdGDKpKTRK 188  

                   EVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsR
                   E +eE IaKSK  K Er++++e    l++kLD   k ++ ll+    +s+
  gi|1578223   189 ELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQILLS---RKSK 235  

                   KsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaek
                   Ks  K+  e k+ +Da YD  ++E+ fe  A+Ps R KTeEElA++E ek
  gi|1578223   236 KSENKEKKE-KPQPDA-YDMMVRELGFEMKAQPSNRMKTEEELAKEEQEK 283  

                   LreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEE
                   Lr+LE eRl+RM +  E   +          kk+k+ S+dDL D      
  gi|1578223   284 LRKLEAERLRRMLGKDE--HENK--------KKPKHTSADDLND------ 317  

                   DKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkK
                        Gfi+d  +         ++ d    +ed   + s    + ++ +K
  gi|1578223   318 -----GFILDKDD-----RRLLSYKDGKMNIEDAQEEQSKGADGQENDQK 357  

                   eavLkddEneDDdLGAELEDkeGeeDdEeD.....edEESDaEldvlkdL
                   e   +  E+  D        ++ e+ dE D++++++d ES aE +   + 
  gi|1578223   358 EEEDESEEEGEDG-------ESCEDPDESDgpdshSDLESSAETEEEDET 400  

                   .KedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPkthe
                   +K +  q   g+ +k     KA   K a          +p+ +  P ++e
  gi|1578223   401 pKKEQRQTPGGKSPKEA--QKA--QKAAAA-------ELPYVFAAPESFE 439  

                   elleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIK
                   el  Ll++ + e   l+VeRI k++hp L+ +N K kl+K+  +LLq+I 
  gi|1578223   440 ELKFLLSGRSMEEQLLVVERIQKCNHPSLAVGN-KAKLEKLFGFLLQYI- 487  

                   DLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevi
                       Dl+         +    kLv +L+ l q +Pe +    + +l++  
  gi|1578223   488 ---GDLATDSTPD---LKTIDKLVVHLYNLCQMFPESASDAIRFVLRDAM 531  

                   kelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmae
                    e+ e +       +P l+ L+++k++gllF+TSDf H+VvTPal+ m++
  gi|1578223   532 HEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQ 581  

                   vLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllv
                    L ++pv Sl+d+ +Glf + ++L+++s S+R+vPe+ ++l +iL+   +
  gi|1578223   582 MLTKCPVTSLRDVVKGLFVCCLFLEYVSLSRRFVPELLNFLLGILY---I 628  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                             tP                                      
  gi|1578223   629 A---------TP-------------------------------------- 631  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIl
                                                                     
  gi|1578223     - -------------------------------------------------- -    

                   aLLsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPv
                          +      k                                   
  gi|1578223   632 -------N------K----------------------------------- 633  

                   aIrllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRE
                                       ks                            
  gi|1578223   634 --------------------KS---------------------------- 635  

                   lRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                        +g     
  gi|1578223   636 -------------------------------------QGCP    639  

gi|159476980|ref|XP_001696589.1|: domain 1 of 1, from 17 to 1120: score 170.1, E = 6.3e-48
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       + + ++K        k+ NPF+ k +k  Fd  Gr   +  g +  
  gi|1594769    17    RPLAAQMK-----SQPKKPNPFELKGSKGHFDTMGR---RSAGKKKN 55   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   +   R+ a+ +Rk+Tl  e+    K + f+D+R+GE +++ s    e +K
  gi|1594769    56 VIEARQEAVNRRKKTLLVEYRSLRKANTFVDRRFGEGDPEMS----EADK 101  

                   MleRfsRErmSQlrLSKreaynlnDGlED.......veedGdrggsSvKD
                   +l R +R+r+ Q++  K+   ++   l D+ +++++ ee++++g s   D
  gi|1594769   102 GLGRLQRQRLKQVK-LKKRGDKFT--LADgaggdgeGEELTHMGRS-LAD 147  

                   DlDsleelgeeLsdddELadeaLDkdflalkrFee...eDAeaeeeq.rG
                   D+  l    e  ++d+E   e   +   ++++ +e+++++A +e +++ G
  gi|1594769   148 DIRNLMDKPEFDDLDEEMVEEL--VSQYHFGGGGEggsDGAGGEGRGpDG 195  

                   AkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllam
                     K+ k +meEiIaKSK yKa +aK++ee e + dk  + fk L+ + a 
  gi|1594769   196 KPKTRKQIMEEIIAKSKAYKALKAKQREEDEQELDKINDEFKQLVRSAAL 245  

                   ekltsRKsGiKkpre.......akedtDaeYDlllkEMvfekRAsPsdRT
                     l       K p e+++ + +a+ + Da YD   +E+ fe  ++ ++ T
  gi|1594769   246 RGLL------KAPGEnkgvkvkAENPEDAAYDVAARELGFESKGAATEPT 289  

                   KTeEElAqkEaekLreLEeeRlkRMee...............teEledgE
                    T+EEl  +E+ +L+ LE eR+kRM+++++++++++++++++ +E+ed+E
  gi|1594769   290 LTPEELLEQERQRLERLEKERIKRMRGgggrggdsededeedEGEDEDEE 339  

                   eEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeE
                   e   G    ++  + S+d L+               +d        d +E
  gi|1594769   340 E---GGRRKRRKAHQSGDALGE--------------DDFDS---DGDEGE 369  

                   ddEdddeeaedsdDdd.....svndGtdlkqk..................
                   ddE++ e   ++dD++++++++v+d   l q++ +   ++++ +++ + +
  gi|1594769   370 DDEGEEEDEDEEDDEEggggkGVSD---LDQRrmkmaagdhplqesfrat 416  

                   ............KeavLkddEneDDdLGAELEDkeGeeDdE.........
                         + + + K   L+d E+eD +     ED+eGeeD+E+++++++++
  gi|1594769   417 aaalaakygvqaKNPYLEDEEEEDEE---GEEDEEGEEDEEgesgdegee 463  

                   ..........eDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANm
                   ++++++++++e edEE   E d   +         +++ ++ s       
  gi|1594769   464 eegesgsgegEEEDEE-EGEEDEEDEEEQLQERRHPKSQPSTS------- 505  

                   KKsadTiPASLdr.......................sipFtidcPkthee
                   K  ad   A+ + +++++++++++++++ +  +++ ++p+ti+ P ++ +
  gi|1594769   506 KPGADA--AAQQQkpqrgqqqqqkpqkpapvldgplDLPYTIPLPASYND 553  

                   lleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKD
                   + +L+k+   ++ ++ + RI+  + + L+ +N K k+  F  +L qh   
  gi|1594769   554 FAALVKGRPADQLATAIARIRAFNAVALATDN-KRKMQEFFGILVQHF-- 600  

                   LfEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevik
                        +  +  +++ + +L  L+  L el+   P+ +a  ++ +l  +  
  gi|1594769   601 -----AMVAGDSPVPVASLDVLTRVLLELLPDVPYYAATVARARLARMAD 645  

                   el......................................aeeykknEhi
                   +l+++  + ++ + ++  +  ++ +++  ++  +++    a++   +   
  gi|1594769   646 QLtsslaglggagarsaadaagtisesvaggvaptkaaaaAAAAAAP-AS 694  

                   kyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdI
                    + S      ++L  l+F+TSD rH+V TP  ll   +L ++ vs   + 
  gi|1594769   695 PWASSRVFCQLQLFTLMFPTSDRRHPVLTPQALLVGKYLNQCVVSNAHEA 744  

                   aiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDV........
                   a Gl L+ +        +R  PeV  +    L  +  p         +  
  gi|1594769   745 AVGLLLCGLMTRIAAPAHRVTPEVLVFYRDCLAAFVPPASKAaaaaagaa 794  

                   ........................ellsitPL..................
                   ++    + ++ +  ++  +++++++ +   P    +++ + +  + ++++
  gi|1594769   795 dtaaaatangagaagkaagkggkgKRKAAAPAaaatssasapaadadndd 844  

                   tFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqt..iteefp
                    F r   +sl++        a  e    ++ +L  +  V  t++  + f 
  gi|1594769   845 AFVRFAPGSLQL----SGSTAAAEEDAPPVPQLDMYA-VLGTpgSDPRFA 889  

                   vdalrsSlLli..........................KEvleLvEeivei
                   +da++ Sl  +   + ++     ++++++ ++     K +    + + e+
  gi|1594769   890 TDAFKLSLMRValcgvrrcaalastpnptapgaaaaaKAAAAAAAAAEEA 939  

                   ...............yyklqAFiEIflPIlaLLsryslkeslpekRlkek
                   +++++++++ +++++y +l+ F   f P  a   ++   e  +   l+e 
  gi|1594769   940 geeggggggvtpgtpYAGLPCFQQLFEPLTAAVAALKRIERQLPAELQEL 989  

                   lldavelveKltedakkerKPL...............AlqeHKPvaIrll
                      +   ++K t+   + r PL ++++ +       +A +     a+r  
  gi|1594769   990 RQAVHSQLTKTTAACVAARRPLvhpgraraaaaaaagAGAVIPAAAVREF 1039 

                   ePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDa
                   +P+FEE y    + + + yDpD+ Rse   Lk++  +E++GAiRElR+Da
  gi|1594769  1040 NPRFEEDY----VSGRD-YDPDRQRSEQRRLKRQVTKERRGAIRELRRDA 1084 

                   kFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    F+a +R  Ekaa d er E  ++ + elq qe  l   
  gi|1594769  1085 VFMAGERDREKAALDGERLESERRFYSELQRQEADL    1120 

gi|170585404|ref|XP_001897474.1|: domain 1 of 1, from 11 to 763: score 151.1, E = 3.3e-42
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k    +           e NPF+ k ++ K +ilG    +     G 
  gi|1705854    11    KKSNNQPV---------ELNPFELKYNRAKHKILGT--KAISAPCGA 46   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG S+ ka e R +Tl  e k + K++ +iD RiGE n         Ee 
  gi|1705854    47 PGLSKKKAFENRTKTLAVEWKERGKRNKIIDQRIGEGNSMMN----AEEC 92   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                      Rf++Er   l++ K     l    +  e +++rg       l ++e+
  gi|1705854    93 ISKRFTAER---LKIFKATNSELV--NNGEEALTHRGR-----ELTEVEK 132  

                   lgeeLsdddELadea.....LDkdflalkrFeeeDAeaeeeqrGAkKsK.
                   ++    + dE +de+++++++ +   a+ +F++  A   e       sK+
  gi|1705854   133 YDRTM-LSDEDDDEVrgggsIGANIVAAVHFGGGNAASVENAT----SKr 177  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklts
                   +  + E IaK K  +  +  +++e eD ++ LDe    ++    m     
  gi|1705854   178 RDFIAELIAKTKQQRYDKKLARDEREDATERLDEKWNKIQQTDVMSGFI- 226  

                   RKsGiKkpreakedtDaeYDlllkEMvfe..kRAsPsdRTKTeEElAqkE
                                       + l E++++++kR++ s+R K eEE+A +E
  gi|1705854   227 --------------------KPLFELQMDsgKRGQASERQKXEEEIAHEE 256  

                   aekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfs
                   +ekL   E  Rl       E     +           k    dD    f 
  gi|1705854   257 REKLIRQEKARLAQLADISE-----A----------KKKSKTDDNKEGFV 291  

                   VEED.........KPKfGfiedlleREDNvdNeEddEdddeeaedsdDdd
                   V  D+++   + +K K G i+ +           +dE d +e+ d+d   
  gi|1705854   292 VKYDssgvlmnaeKLKKGRIK-VIR------IDSSDEEDESESDDLDE-- 332  

                   svndGtdlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaE
                                     d +eDD       D      dE+ +   S +E
  gi|1705854   333 ------------------DKEEDDF------DAM-VNGDEQMDLPPSSSE 357  

                   ldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtid
                              a+   +  i       A                +pF id
  gi|1705854   358 ----------NAATDAEMEIQKR-WQNA---------------ELPFVID 381  

                   cPktheelleLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvv
                    P ++  l  Ll   + +     ++R ik++hp L e+N K++l+ + v 
  gi|1705854   382 LPQNYQNLKKLLDAQSDANCEVFIKRLIKLYHPSLREGN-KSRLGRLFVL 430  

                   LLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqelPeklaislse
                   LL++     +Dls+    k   + L+      L+ l q++ e  a++++ 
  gi|1705854   431 LLRYY----DDLSKEREAK---IALFGYIARGLYYLMQLNVEHSARCMRA 473  

                   ellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPa
                    l+    + a + +    + +  +    f+kLv +l++  D  H+Vv+P 
  gi|1705854   474 LLRQQYAQHARAPREM--FTFRCIA---FLKLVLILYPVRDVFHPVVSPT 518  

                   lllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqi
                   l + +   s  +  S kdIa  l +v+iV  f+  SkRy+PeV+ +l + 
  gi|1705854   519 LAFACSLVSTVRMCSIKDIARMLLMVRIVGSFVEESKRYLPEVIAFLHGV 568  

                   LftllvpKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepq
                   L+ + ++    +   +       +               +  +++l    
  gi|1705854   569 LL-MAIE----NSDDEHC-----P--------------TTTFPISLPHRR 594  

                   rLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiE
                    L  +D               + S+  i    +L+   + +         
  gi|1705854   595 MLFVTD---------------DCSMIEI--PSQLDIKQIFVDDTDR---- 623  

                   IflPIlaLLsryslkeslpekRlkeklldavelveKltedakkerKPLAl
                      P l LLsr++    +p+      ll  + ++e ++    +    L  
  gi|1705854   624 ---PLLGLLSRLPR-NLYPSQ-----LLTELSALESFIT--AQSSRNLLK 662  

                   qeHKP....vaIrllePKFEEnyDDKRsPdksSyDpDkeRs....elnKL
                   q  +P ++++ + lleP+F Eny    +  k  y    ++ +++ e++ L
  gi|1705854   663 QLQRPakqkKMLDLLEPRFDENY----NIEKAHYEKNTAKKskkvEIKQL 708  

                   kaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqe
                    +k K+E +G++RElR+D +F  r++++E + +d++r EK k +  +lq 
  gi|1705854   709 TKKYKKELRGTVRELRRDNQFLNREKRQEMLESDKARKEKTKWLISTLQG 758  

                   qegAl<-*
                   qe +    
  gi|1705854   759 QESEY    763  

gi|195110695|ref|XP_001999915.1|: domain 1 of 1, from 1 to 416: score 49.2, E = 1.6e-11
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                                                                     
  gi|1951106     -    ----------------------------------------------- -    

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                                                    +Pkt+e+++eLl k   
  gi|1951106     1 ---------------------------------MPKTYEDFTELLAKYTP 17   

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                   ++  ++VeRIik++hpKL+++N +e +vK+  +LL +IKD+fED+se+di
  gi|1951106    18 AQQVIVVERIIKCNHPKLEGVN-REDVVKLFGFLLHYIKDMFEDASELDI 66   

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                    ++  f L + L+++L+ l  ++  +    +s++ll+vike+++e++kn 
  gi|1951106    67 GSH--FKLVSQLMPHLHDLVHLNIDR----MSNTLLDVIKEKYAEFRKN- 109  

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h+ yP l++L++Fk+v++l+sTSDfrH+  TP  ++m++ Lsr +v++++
  gi|1951106   110 HKIYPTLDTLIYFKIVSNLYSTSDFRHPLATPTYIFMQHMLSRARVRTRQ 159  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsit
                   dIa+Glf v+i L+f s SkR++P+++++lq+i++ + +pKR  e  +i 
  gi|1951106   160 DIAMGLFVVTIALEFGSRSKRLLPAIFNFLQGIVH-MAIPKRQQERVEIA 208  

                   PLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteefp
                   P +Fe+d  ++++k   l++++   +   l pq+L++aDLVtqti  +f+
  gi|1951106   209 P-PFEQD--GPFSK---LLAIPVTSDTKALQPQKLQPADLVTQTIDVDFK 252  

                   vdalrsSlLliKEvl.eLvEeiveiyyklqAFiEIflPIlaLLsryslke
                   v+al+s l l K + +e   e+ +++y++        P+l L  +++   
  gi|1951106   253 VRALDSTLCLLKQIFdEQMGEHTGACYLAA-------PFLPLIEQLPM-N 294  

                   slpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFE
                    +pe+ ++++   a   +   +e   +++KPLA+  +KP+a+rlleP+FE
  gi|1951106   295 LYPEH-VQQHCAEAKSTLKSVAE---QKMKPLAPPDKKPKALRLLEPRFE 340  

                   EnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvar
                    +yDDKR+P++s     k ++e++KL++k+KrEkKGAiRE+R+D+ Fv+ 
  gi|1951106   341 MVYDDKRRPKMS-----KQKEERAKLLHKIKREKKGAIREIRRDTAFVQD 385  

                   lRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   lRlk++ ++d er EK+k+i++e+++q+g+l   
  gi|1951106   386 LRLKQQIQSDNERREKVKRIYQEASVQQGEL    416  

gi|255726222|ref|XP_002548037.1|: domain 1 of 1, from 1 to 544: score 30.5, E = 6.9e-06
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                            +K                        il             
  gi|2557262     1    ------MK------------------------ILVI----------- 6    

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                               +iD       ++ s        
  gi|2557262     7 ----------------------------IID-------DLRS-------- 13   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                              Q ++S+ +a  ++                          
  gi|2557262    14 --------V--QGKISNNNA--FS-------------------------- 25   

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                                                                     
  gi|2557262     - -------------------------------------------------- -    

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                                                             t      K
  gi|2557262    26 ------------------------------------------T------K 27   

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +p  ++      YD++++E+  + R  P+dRTKTeEE+ ++ +ek  +LE
  gi|2557262    28 TPEQIE------YDSKVRELTYDRRDVPADRTKTEEEIRKEYEEKMKKLE 71   

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                     Rl+RMe+  E+  +                 +dDLdD           
  gi|2557262    72 ADRLRRMEGFVEDDREQQ---------------GDDLDD----------- 95   

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                    f+                 +dd+e e+       +        Ke    
  gi|2557262    96 DFWG----------------GDDSENEENGF----SI-------KES--- 115  

                   ddEneDDdLGAELEDkeGeeDdE.eDedEESDaEldvlkdLKedeaqplk
                                 D eGe+ +++eDe+E                     
  gi|2557262   116 --------------DNEGEDAEGsEDEGEG-------------------- 131  

                   geaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkld
                        a               P  L++ i     +P t++e+l+ ++   
  gi|2557262   132 ----RAK--------------PRKLQTVI-----MPLTFDEFLQEISAVE 158  

                   leDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQd
                       +  ++++   + p L  +N Kek+++F  +LL +I  L+  l+   
  gi|2557262   159 STKQIEYIKKVCNTYKPGLGQGN-KEKMGNFAGILLDYI--LH--LAD-- 201  

                   ikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykkn
                     k   f+ +e  v+    ++++l e ++ sl e+++e ik+ + ++ k+
  gi|2557262   202 --K---FEDFEPFVK----ILKKLAETYNESLVEKVREHIKQIQSRINKP 242  

                   EhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSl
                        +  +dL fF +++ l+s SD +H+V+TP+l+lm e Ls +    +
  gi|2557262   243 -----LKASDLAFFVIIAYLYSSSDHYHIVITPCLILMNEILSTIIYHPR 287  

                   ..kdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVell
                   +   I  G fLv + L +q+  kRy PeV+++++ ++f ++vp  + e l
  gi|2557262   288 diTTIGQGVFLVDVLLMYQRFAKRYDPEVINFIEHAIF-MIVP--EPEKL 334  

                   sitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtite
                    i  L+ +     s  k     n+     +++ e    s a      i  
  gi|2557262   335 DISKLLSISE---SVAK-----NVNVQFSMNKSEKFDDSEAN--VLSIKG 374  

                   efpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrysl
                    ++ d+ +  lL     ++     v+ ++  ++ iE++  +   L   + 
  gi|2557262   375 LYSEDLSKPLLLAK--LVSIMNKCVTLWKEKSSLIEVLESFISILKHVTK 422  

                   keslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePK
                    +  p +     ll    ++ +      k rKPL lq H+ +aI + +PK
  gi|2557262   423 -YNAPLT---GPLLTRFTKLHDNLV---KDRKPLTLQHHRALAIATFAPK 465  

                   FEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFv
                   FEEn+    +Pdk+SyD+ +eR elnK k++lK+EkK A + +R   +F 
  gi|2557262   466 FEENF----NPDKKSYDINRERQELNKVKHQLKKEKKSALKDIRQENRFL 511  

                   arlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ar+ + Ek a   e+h Km+ i+n +q +egA+   
  gi|2557262   512 AREQIAEKKAMYDEYHKKMANIYNSIQSEEGAE    544  

gi|226453879|gb|EEH51187.1|: domain 1 of 1, from 2 to 1046: score 17.7, E = 0.049
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                                                        Gr     Kge+  
  gi|2264538     2    ----------------------------------GR---VYKGEKHN 11   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                       Ra +  kRk+Tl +e+  +nK +af+D+R+GE +  L+     Ee 
  gi|2264538    12 IIAARAAGNTKRKNTLLKEYRASNKANAFVDRRFGEGDATLT----PEER 57   

                   MleRfsRErmSQl...rLSKreayn.........lnDGlEDveedGdrgg
                    + R +R r+ Ql+++r  K++  ++++++++  +nDG   +  dG   +
  gi|2264538    58 QIGRLTRTRLRQLgtgRGGKKSFALgddddgnawMNDGDGGDDADGGTTL 107  

                   sSvKDDlDsleelgeeL......................sdddE...Lad
                   +     +D+ +e + + ++  ++ ++++++ +++ ++++sddd +++ + 
  gi|2264538   108 THGGVAIDEATEKRRSEhhlarratttrrsardgfggsdSDDDFgggMDR 157  

                   eaLDkdflalk...rFeeeDAeaee.................eqrGAkKs
                   +      l+++++++++++D+ + e++ ++++++ +++++++e+r   K+
  gi|2264538   158 AI--TGALHFGggeGNGDDDDGGFEpslkrgdhgvdgdddggERR---KT 202  

                   KkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt
                   K+EVm E I KSK  Ka +  ++e  eDl dkLD  f  L    a   + 
  gi|2264538   203 KAEVMTELIEKSKYHKALKTRQREADEDLLDKLDGTFAALSGDGAFRAVL 252  

                   sRKsGi..............KkpreakedtDae.................
                   s+  G  ++++ ++++++++Kk +  +++  a+++ + + + ++ ++  +
  gi|2264538   253 SKGVGHlkpdgwtrdgnrrdKKNQKGETNAAAPsgidldakakeagevvk 302  

                   ..YDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMee.
                   ++YD+  + + +e R++ +dRT T EE+ + Ea+kL+e E  RlkR +++
  gi|2264538   303 ddYDKITRALALEARGRAADRTRTQEEIDAAEAAKLEEAERGRLKRQRAg 352  

                   ....teEledgEeE...iGGEESvkklk......................
                   +++++  l+dg+ ++ + GG    ++ k+++++ ++++++++ ++++++ 
  gi|2264538   353 dsddDVALSDGDDDgmrAGGGYAARRAKskgsrakdddgddgakkekkka 402  

                   ....vrSvdDLdDsfsV.............................EED.
                   ++++ +++dDL+D f V+++++++++++++++   ++++   ++++EE++
  gi|2264538   403 rkdgRIGGDDLGDDFAVgsdgdddddgkggggaffggdplaygsssEEEg 452  

                   ...................KPKfGfiedlle..........REDNvdNeE
                   + ++ + ++ +++  +++ K   G i+dl+ ++++ ++ +  +D  d++E
  gi|2264538   453 dvegldakeaerramtkslKREVGSIKDLERgkkrlrklglLDDGGDAGE 502  

                   ddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAELEDke
                   d Edd +     dDdd + d                ++DDd      D+e
  gi|2264538   503 DEEDDGDDDDGDDDDDQEDD----------------DDDDD------DEE 530  

                   GeeDdEeDedEESDaEldvlkdL..Kedeaqplkgeaikasv........
                    ee+dEe e EE D E  v  d ++K d   +   +  ++sv++++++ +
  gi|2264538   531 EEEEDEEEEEEE-DEEKKVADDVddKSDIVSIPDNSDTSISVtpsdedag 579  

                   ...........keKANmKKsadTiPASLdrsipFtidcPktheelleLlk
                   + ++++++  +++K+    s+   P S  + +pFt+++P t e l + + 
  gi|2264538   580 gaesdsdpaarSKKT-ETASSPPRPTSTSTELPFTFPMPETPEQLNDIVG 628  

                   kldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDls
                    l+ +D +l  eRI+k+h p Lke+N ++k   F   LLq          
  gi|2264538   629 ALSPADTALALERIRKCHAPTLKEDN-RKKTQTFLGLLLQRF-------E 670  

                   eQdikknLNfqLLekLveaLielaqelPeklaislseellevikelaeey
                   +++  ++L    L  L       a + P ++a  ++ +l+++  +l ++ 
  gi|2264538   671 VLAGESPLPAVYLDILAANVAAVAASVPFFAATAARARLEKMSARLRAAL 720  

                   kknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspv
                   +   +  +P   + +++ L +  F+T D+ H+V TPa l +  vL  + +
  gi|2264538   721 RDD-ETGWPPARTILLLALFAEVFPTTDKQHPVCTPAALYIGNVLAHCAI 769  

                   sSlkdIaiGlfLvsiVLkfqsiSkRyvP.......eVvyalqqiLftllv
                   +  ++ a   +   +   +       +P++++++++      +       
  gi|2264538   770 RGAREAALAVVFSALAAAYS------LPggggggdATSKKKKKKKK-NDA 812  

                   pKRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaD
                      D       P t  +    sl     l + +a+ +s       L+  D
  gi|2264538   813 D-ADADADADAPTTGVLA---SLAS--ILSAAPANAPSDW-----LPNGD 851  

                   LVtqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP..
                               d+  ++lL     + ++ +      k ++  E + P+ 
  gi|2264538   852 ------------DDKHAVLLAA---VKTLRTLCAPATKTPSAREFLAPtv 886  

                   ..IlaL...LsryslkeslpekR..........lkeklldavelveKlte
                     I  L+ +L   +  e +  ++++++++++  l   l+ a+e+   l +
  gi|2264538   887 vaIERLgatLRGVTVEENDANTKsktpppppllLTGALKRAAEACVALEA 936  

                   dak......kerKPLAlqeHKPvaIrllePKFE.EnyDDKRsPdksSyDp
                   d  +   ++++r PL  + +K  aI   +P +E E+y      + + yDp
  gi|2264538   937 DVApafassAKRPPLTWRLKKVEAIKVYNPMYEiEGY----QKGRD-YDP 981  

                   DkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEK
                    +eR+e +KL+++lK+E++GA+RElRKD +F a +R kE  a   er E 
  gi|2264538   982 NRERAEAKKLRRQLKKEARGAVRELRKDNRFLAEERHKESSAAADERGER 1031 

                   mkkivnelqeqegAl<-*
                    +   ++l   eg l   
  gi|2264538  1032 QRDTLAFLEKLEGDL    1046 

gi|224012905|ref|XP_002295105.1|: domain 1 of 1, from 40 to 1094: score 11.8, E = 0.33
                   *->keedreeKKKAvakiqkefNPFdvkv.akrKFdilGrsKtkvKgeeG
                       e++r         ++ +     ++v+   K   lGr         +
  gi|2240129    40    FEYARTTN----SATRVKHHVHNRIVpGQLKPNSLGR---GGASNAR 79   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGE..rnkhL....sG
                       S a+ +++R   l  +++   K + fiD+RiGE +r   L ++++G
  gi|2240129    80 STQSSLARSIQRRQTHLKSQLQSEGKANSFIDRRIGEagRRHGLvedgGG 129  

                   DqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedG.......dr
                       E++Ml R   Er   +r SKr a +++  lE  e+dG+++++ ++r
  gi|2240129   130 GRTKEDVMLKRIVQER--VRR-SKR-AGKFS--LEEEEDDGgggggltHR 173  

                   ggsSvKDDlDsl...................................eel
                    g  +   + sl   ++ + ++++++++ ++ +++++ +++ +++++ e 
  gi|2240129   174 VGIVMVYCILSLfmfstlqctnhtnhdsaqrlpqgktidesytgkpqDEM 223  

                   geeLsdddELadeaLDkd.flalkrFeeeDAeaeeeqr............
                   +  Lsddd  + +   +d+ +++++   + + a e+++ ++++++++++ 
  gi|2240129   224 DIILSDDDQDDLDK--VDtMMHFGGGKFDKDNAIERGAyggeggqggqdl 271  

                   .GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsll
                   + A  s kE +e  I   K+ KaEr K Ke      +  De f  L  ll
  gi|2240129   272 gVAYRSRKEELEDRIRMKKFEKAERMKRKEDQAETFETMDESFAELAQLL 321  

                   a........mekltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPs
                     +++++++ ek ++RK G  +  + +   Da  D+  kE  fe   + +
  gi|2240129   322 QfrdkeqerTEKAKARKMGTLNADDVE--MDA-WDKEMKEYLFERKVKAT 368  

                   dRTKTeEElAqkEaekLreLEeeRlkRMeeteEled......gEeEiGG.
                   dRTKT+EE+A++Ea++L +LE  Rl RM ++ E ed+ ++ + +e  GG+
  gi|2240129   369 DRTKTPEEIAKEEADRLHKLETRRLARMAGDFE-EDdlsdisDDE--GGr 415  

                   .......EESvkklkvrSvdDLdDs.fsVEE..DKPKfGfied...lleR
                   +++++++E S kk  +   + L Ds++  EE++D+    f  d+   l++
  gi|2240129   416 krkrskkEQSKKKRDHSNPEELSDSeDEKEEsgDRREVRFTADglvYLDK 465  

                   EDNv..dNeEddEdddeea..edsdDddsvndGtdlkq.kKeavLkd...
                   + Nv +  +E+ + +++ +++e+sd+ d+  +G ++  +  ++ L d+ +
  gi|2240129   466 DGNVvgKVGEEKDEENDAIseEESDGSDGDLSGSEEEDsAAGHDLGDsvd 515  

                   .......dEn.eDDdLGAE.LEDkeGeeDdE...................
                   + +  ++dE+++D + GA ++E ++G   +++ + +++ +++++  +++ 
  gi|2240129   516 easaansDEDgSDEESGANpVELTKGMKVQGnyrakeqyggkenwyngei 565  

                   .................eDedEESD....aEldvlkdLKed.eaqplkge
                   +  +++ ++++  + + eD d+E D+  ++ ++ l +  e++ea+   + 
  gi|2240129   566 tavrkdcngntvydvtyEDGDFE-DgmiqSNVRALPKSQEEkEAEMARET 614  

                   aikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl.
                    ++   k+K   K  a          ipF ++ P+t + l   +  ++ +
  gi|2240129   615 EVSLAKKKKLKAKIRAKE-------TIPFVFEVPTTLDSLHNVIATHASt 657  

                   .eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLL.qhIK...DLfEDl
                   ++D  lI++RI + +++ L   N Ke++ +F+ vLL+++I  ++ +fE  
  gi|2240129   658 gADASLIIQRIHTTNSVRLNHKN-KERMQNFYDVLLrRFIAvgdAIFESG 706  

                   seQdikknLNfqLLekLveaLielaqelPeklaislseellevikelaee
                      + ++    + L+  ++ L+ ++q  Pe ++   s +l    k +a++
  gi|2240129   707 NGGPDLER--YEQLNSITKTLYAMSQDSPECAGAVWSRRLGIFQKAFAKR 754  

                   ykknE.....hik......yPSlkdLvfFkLvgllFsTSDfrHlVvTPal
                    +  E  + ++ ++++ + +PS + L++ +    +F+  D+rH+VvTPal
  gi|2240129   755 LRDVEvvqlgDACegeftaWPSTGMLLLMRALPHIFPSTDKRHAVVTPAL 804  

                   llmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiL
                    l+ + L + p+ S  d+ +Glf   +  ++    kR+ Pe   +l + L
  gi|2240129   805 VLLGQILAQTPIYSQYDVVMGLFCSGLMIEYTKDAKRLPPEATAFLAGVL 854  

                   ftllvpKRDV.ellsitPLtFerdRLDslekGLPldnlfavkestllepq
                     l     DV   ls  P    ++ L+s +kG  l+nl  +  s l+   
  gi|2240129   855 R-LFAD--DVaAALSRSP----LPSLGSTSKGSTLLNLR-KELSDLINEG 896  

                   rLslaDLVtqtiteefpvdalrs...SlLliKEvleLvEeiveiyyk..l
                    L l       i   +  d+ +s+ +Sl  i  +l Lv  ++ +++k+++
  gi|2240129   897 DLGLNN-----IRLSLEKDDIQSeanSLSTISFALHLVQQAINAFGKteE 941  

                   qAFiEIflPIl.aLLsryslkes..lpekRlkeklldavelveKltedak
                    +  EIf  +++a+L   ++++  +lp   +k  +  ++  ++   +   
  gi|2240129   942 GSEREIFSEVMkAMLCIDGSRKDltLPLS-VKNAIAETARVASSTCA-SG 989  

                   kerKPLA...lqeHKPvaIrllePKFEEnyDDKRsPdksSyDpDkeRsel
                    er PL +++ ++ K +aI +l+P+ E       +  +s    Dk + +l
  gi|2240129   990 EERRPLQrrkAASAKDLAIKTLAPRMEDPS----RYSMS---KDKGKTQL 1032 

                   n....KLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkk
                     +++  ++  KrE K A+RElR D+ F+  +R+k k a d    EK  k
  gi|2240129  1033 QaehdRHRREYKREHKAAMRELRLDSAFIESERRKAKDAADGKAKEKRHK 1082 

                   ivnelqeqegAl<-*
                     + l  ++  +   
  gi|2240129  1083 NFAWLEQEQATM    1094 

gi|219121013|ref|XP_002185738.1|: domain 1 of 1, from 10 to 959: score -1.2, E = 0.39
                   *->keedreeKKKAva.kiqkefNPFdv..kvakrKFdilGrsKtkvKge
                       + +   K  A+ + +    NPF+++++  + K  +  r   +    
  gi|2191210    10    RSLASPPKGLAIRgGTNGATNPFEItsRHKRPKHEVHNR--KIPTKN 54   

                   eGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLe
                   + kP+   a a+ +R+++l   ++k+ K + f DkRiGE +   +     
  gi|2191210    55 VAKPS-ALAQAVSRRRNALSEALQKSKKNNTFADKRIGEYDRSMT----S 99   

                   EeKMleRfsRErmSQlrLSKreaynlnDGlEDveedG......drggsSv
                    e  l+R  REr   +r SKr+  +++  l+D  edG++++ ++ g s  
  gi|2191210   100 DEQNLARLVRER--ARR-SKRST-KFS--LNDEDEDGgqttltHKGKS-- 141  

                   KDDlDsleelgee.LsdddELadeaLDkdflalkrFee............
                      +  +   +   LsdddE +   LD+  +al +F+++ ++  ++++  
  gi|2191210   142 ---ISDMSARDHViLSDDDEDDIGNLDAADTAL-HFGGgcrsavpddgyy 187  

                   ...eDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidk
                   +++ +A + +       + k  ++  I   K  KaEr K +e      + 
  gi|2191210   188 gptAGAQGKDMSS-MYMTRKMELDDLILRRKIKKAERMKSREDQTEAFEA 236  

                   LDeNfkdLlsllam........ekltsRKsGiKkpreakedtDaeYDlll
                    De f  L + l+ ++++++ +e ++s+++G+  p +      +  D+  
  gi|2191210   237 MDESFAELSNMLSFrdkekeirEHVKSKRAGMLAPED--QEMED-WDKQM 283  

                   kEMvfekR.AsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEledg
                   k  +f  R+ + +dR KT+EE+A++E ++L eLE  Rl RM+++  + d 
  gi|2191210   284 KQYQFNERkVKATDRVKTPEEIAKEEVDRLHELETRRLARMNGDFVDDDL 333  

                   EeEiGGEESvkklkvr......SvdDLdDsfsVEED...KPKfGfiedll
                        GE    k k r+++  + ++ LdD   VE+D ++K    f  d l
  gi|2191210   334 SDISDGERNLQKRKTRkstlasTAEALDD-SEVEDDaeeKVTTRFTADGL 382  

                   eREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDD
                           e d ++         D+d  n       +  a     E+ DD
  gi|2191210   383 V-------EVDRNGVVAKKVNAPDNDALNGAFAKGSRVSACYHAKEQLDD 425  

                   dLGA......................ELEDkeGeeD..........dEeD
                   d  A+  ++  ++   ++++    + E +D   +eD+ ++++ ++ dE  
  gi|2191210   426 D--AtwfngvvsgvyarddglvvyniEYDDGD-FEDgvehrhvrpaDETK 472  

                   edEESDaEldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLd
                   ++      ++     K +    lk + + a   eKA              
  gi|2191210   473 SVRK----VEEIEANKQEQELELKRKRLRAK--EKA-------------R 503  

                   rsipFtidcPktheelleLlkkldl..eDkplIVeRIikahhpKLkeeNR
                     +pF ++ P+t e+l + +   + +++D  lI++RI   +++ L   N 
  gi|2191210   504 AELPFVFEVPTTLEALHDMIGTYAStgADASLIIKRIHASNSVRLDRRN- 552  

                   KeklvKFs.vvLLqhIK...DLfEDlseQdikknLNfqLLekLveaLiel
                    ek+ +F++v+  +++  ++ ++   s     +   f  L  L    + +
  gi|2191210   553 AEKMQNFYdVAIRRFVAvgdAIY--RSGDGDSELGRFKQLDELARIMYTM 600  

                   aqelPeklaislseellevikelaeeykknEhik..........yPSlkd
                   aq   e +      +l    +  a++ +   + ++++++++++ +PS++ 
  gi|2191210   601 AQDSAESATAVWGRRLGVFQNAHAKRLRDA-ELDrdeddedqsaWPSIGV 649  

                   LvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLv
                    + ++ +g +F+  D+rH ++TP ll++ +  s+ pv S  d   G    
  gi|2191210   650 FLALRAIGHIFPVTDQRHQIITPTLLMLGQIVSQTPVLSIYDLVVGTMCS 699  

                   siVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRL
                    +  ++    kR  Pe + ++ + L  +        l+   P  + ++  
  gi|2191210   700 ALLIEYTKAAKRISPEAIAFIAGVLRMFASD----SLKRQGP--YSLP-- 741  

                   DslekGLPldnl.......favkestlle..pqrLslaDLVtqtiteefp
                    slek     ++++++ ++f    s+  e  p +Ls  +      + e p
  gi|2191210   742 -SLEK-----AVtgeqfdsFRALASSYQEvyPPNLS-FE-RIGMFSAETP 783  

                   vdalrsSlLliKEvleLvEeiveiyyklqAF...iEIflPIlaLLsrysl
                     +l + l l+ Ev  L    ++i      F++  E  l I      ys 
  gi|2191210   784 AALLYAALHLV-EVTVLCLSGSGIDAERELFhtlAECVLNI----KPYSK 828  

                   keslpekRlkeklldavelveKltedakkerKPL...AlqeHKPvaIrll
                   k  l    l+ek  +a+e +eK        r PL++++l   +   I +l
  gi|2191210   829 KHTLCKC-LQEKAASAAECLEKACK-LENARPPLrrrSLPTIRDTMIKSL 876  

                   ePKFE..EnyDDKRsPdksSyDpDkeR....selnKLkaklKrEkKGAiR
                   +P+ E+ E y    s  k+     k ++ +++ l   ++ l+rE K   R
  gi|2191210   877 APRIEnaEKY----SMSKD-----KGKnapqAALDRTRRELRREHKAVSR 917  

                   ElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   ElR D++Fv r R++E+ +kd++  +K  k++  l  ++  +   
  gi|2191210   918 ELRLDSSFVERARREEQTKKDSAAQAKRQKAYGWLENEQATM    959  

gi|195110697|ref|XP_001999916.1|: domain 1 of 1, from 9 to 421: score -41.5, E = 0.66
                   *->keedreeKK.........KAvakiqkefNPFdvkvakrKFdilGrsK
                      + +++ +KK+++++++ + A+  + k+ NPFdv+v+k+KF+ilGr  
  gi|1951106     9    NADAVYSKKsgktsnpfdTAISQTSKRLNPFDVHVNKEKFKILGR-- 53   

                   tkvKgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhL
                    ++K+++G PGVSRaka+ kR+ T+++++++k+K++ f D RiG   khL
  gi|1951106    54 -ICKHDRGLPGVSRAKALKKRAETIGKQYEVKHKTNKFRDHRIG---KHL 99   

                   sGDqLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSv
                   +G+qL+E++M++R+++E++SQ+r +  +a ++n  l+D+e++++rg++  
  gi|1951106   100 TGEQLTESVMNARYLAEKLSQVR-ASNKAQKFN--LNDDELLTHRGQT-- 144  

                   KDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAk
                      l+++e++++e+sdd+EL de LD+ f+ +++F++  +  +++q    
  gi|1951106   145 ---LEEIEKYRDERSDDEELEDEGLDAEFTSAAHFGGGADATQDRQT--- 188  

                   KsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamek
                        ++eE+I ++K++K+E+aK K+ev Dl++kLD+N+kdLlsl+a  k
  gi|1951106   189 -----AIEEMISEQKRRKNEIAKDKDEVHDLTEKLDANYKDLLSLVA--K 231  

                   ltsRKsGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqk
                    t      K+++ ak+++D+ YD+llkEM+fe+R+s++d+++ +E lA++
  gi|1951106   232 AT------KDEQIAKPPPDD-YDKLLKEMIFEPRGSVTDKLIKPEDLAKQ 274  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                   Ea++L+ LE+eRl+RM+++ E     e       +    +rS+dDLdD  
  gi|1951106   275 EAARLEQLENERLRRMKADDE---QPE-------TTVQPHRSADDLDD-- 312  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                            G++            + +d+ dd++a+d+d+    n+Gt+l
  gi|1951106   313 ---------GYFA----------TGVEDDADDTLAYDLDG----NLGTHL 339  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                   + kKe      E++ D      ED +  e dEeD+dEE            
  gi|1951106   340 NSKKE---NPKEQSNDK----SEDGSDDEGDEEDDDEE------------ 370  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                         + g+    +                                   
  gi|1951106   371 ------EEGSDSDSE----S------------------------------ 380  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                                              +++N                   
  gi|1951106   381 ---------------------------EADN------------------- 384  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                      ls +                                           
  gi|1951106   385 ---LSDLKATDS-------------------------------------- 393  

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                                                                     
  gi|1951106     - -------------------------------------------------- -    

                   srspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpK
                                                                   + 
  gi|1951106   394 ------------------------------------------------E- 394  

                   RDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLV
                            P     d                            s  D  
  gi|1951106   395 ---------P-----D----------------------------S--D-- 398  

                   tqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaL
                                      +                              
  gi|1951106   399 -------------------S------------------------------ 399  

                   LsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaI
                          e+ p+               K+t             +  P+a 
  gi|1951106   400 -------EEAPQP--------------KKTK------------KQIPKA- 415  

                   rllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElR
                           E +                                      R
  gi|1951106   416 --------ESF--------------------------------------R 419  

                   KDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    D                                        
  gi|1951106   420 ND-------------------------------------    421  

gi|224111890|ref|XP_002316014.1|: domain 1 of 1, from 28 to 620: score -95.8, E = 1.3
                   *->keedreeKKKAvak.iqkefNPFdvkvakrKFdilGrsKtkvKgeeG
                       +  +++K  A  k+ +   NPF+ + ++rKFdilG+   k+Kgee 
  gi|2241118    28    APNSVAMKASAASKdNKNSSNPFETIWSRRKFDILGK---KRKGEEL 71   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                     G SR +a+ekRk+Tl +e++ + Ks++f+DkRiGE+n  L+    e++
  gi|2241118    72 RIGLSRCRAIEKRKKTLLKEYEESGKSSVFLDKRIGEQNEQLG----EFD 117  

                   KMleRfsRErmSQlrLSKreaynlnDGlE.DveedGdrggsSvKDDlDsl
                   K ++R++REr  Ql+  K++ ynl+DG+E+D+    ++g  S +DD++  
  gi|2241118   118 KAIIRSQRER--QLK-NKKSKYNLSDGEEdDDFAIPNLGPLSGQDDFEDE 164  

                   eelgeeLsdddELad....eaLDkdflalkrFeeeDAeaeeeqrGAkKsK
                    +++++ +d d    +++++    + l + +   +   +ee +    K+K
  gi|2241118   165 ILSDDDGDDADADRTskkpAI--LRQLNAHGLPQDAVHGEENKP---KTK 209  

                   kEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllameklt.
                   kEVm E+I KSK+ Ka +aK Kee e l+++LD+ f +L+ + a  +lt+
  gi|2241118   210 KEVMQEVILKSKFFKAQKAKDKEENEQLMEELDKSFTSLVQSQALSSLTe 259  

                   .....sRKsGi..........Kkpreak.........edtDaeYDlllkE
                   +++ ++ K+ ++++ ++++ +K++ + ++++++ +++e +D  YD+l+ E
  gi|2241118   260 pgkmnALKALVnkdipnehvkKDELPVIqkpetfkqqEQPDS-YDKLVYE 308  

                   MvfekRAsPsdRTKTeEElAqkEaekLreLE.............eeRlkR
                   M  + RA+PsdRTKT+EE+AqkE+e+L+ LE +  +  ++ ++ e R+kR
  gi|2241118   309 MAIDSRARPSDRTKTPEEIAQKERERLEQLEasawhyyhhysdlEDRKKR 358  

                   MeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsV.EEDKPKfGfied
                   M      +d+E +     S  +++ +S+dDL+Dsfs  EE     G+ ++
  gi|2241118   359 MLVADDSSDEENDDVEKLSAQRPRSISGDDLGDSFSLyEEPGTTKGWVDE 408  

                   lleRE..DNvdNeEdd.........EdddeeaedsdDddsvndGtdlkqk
                   +l R + D  dNe dd+++++ + ++d d+e  d+dD     dG d    
  gi|2241118   409 ILARKeaDDSDNEDDDsseesasanDDGDDEGSDEDD----TDGDDDEHE 454  

                   KeavLkddEneDDd.LGAEL.EDkeGeeDdEeDedEESDaEldvlkdLKe
                   K   Lkd+E++DDd+LG +L+ED+e       D++E    E   +k+ K 
  gi|2241118   455 KSTSLKDWEQSDDDnLGTDLeEDEE-HGSHDGDDGEI---EPISHKKSKK 500  

                   de.aqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                    e+ +p kg   +  +k+K   +   +T     + +ip  i+ Pk++ee+
  gi|2241118   501 TEpVEPRKGDEKSLDGKKKKANREQHST-----QPDIPHIIEAPKSFEEF 545  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                    + l+ +++e ++l+V RI+k + + L++eNRK+            I   
  gi|2241118   546 CAILENCSNENVILVVDRIRKSNAIQLAAENRKK------------I--- 580  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                                                                     
  gi|2241118     - -------------------------------------------------- -    

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                                                                     
  gi|2241118     - -------------------------------------------------- -    

                   srspvsSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpK
                                           q                 +f + ++ 
  gi|2241118   581 ------------------------Q-----------------VF-YVIE- 587  

                   RDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLV
                                  d                            + +D  
  gi|2241118   588 -------------FSD----------------------------QATD-- 594  

                   tqtiteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaL
                             d +  S+L+              + ++             
  gi|2241118   595 ---------GDECGDSILFC-----------NMCSSAN------------ 612  

                   LsryslkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaI
                      +++     +                 t                    
  gi|2241118   613 ---LTN-----SC----------------TI------------------- 619  

                   rllePKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElR
                                                                     
  gi|2241118     - -------------------------------------------------- -    

                   KDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                         l   
  gi|2241118   620 --------------------------------------L    620  

gi|239871791|gb|EER01571.1|: domain 1 of 1, from 11 to 776: score -108.9, E = 1.6
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFd.ilGrsKtkvKgeeG
                      ++ dr+          + fN Fd +++k  ++++lG       g ++
  gi|2398717    11    SSRDRQRP-----SDGSGFNQFDMRANKTARKpVLGM--AQQHGSRR 50   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                     + S+  a   Rk  l +ef    K+g f+D+R   +    +      e
  gi|2398717    51 NMSESKSYAKTSRKDSLLKEFRALGKTGSFKDRRLDAKARGMT----ADE 96   

                   KMleRfsRErmSQlrLSKreaynlnDGlEDvee............dGdrg
                      +Rf  Er+ Q   SK++ +    GlED ee++++ ++ +++ +++ g
  gi|2398717    97 LASARFRKERIRQQEKSKKKRNAAF-GLEDEEEgegsaegvehnlLTHGG 145  

                   gsSvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeq
                              +   +eL  d + +++  D+ ++      e  Ae+ +  
  gi|2398717   146 K-------PVKTMTADELRGDPLSDSDD-DEELK-----KEIEAELMKTT 182  

                   r.GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsl
                   ++G +  K+    Ei aK K yKa r+ eK + e +   LD+ +k +l++
  gi|2398717   183 EhGKHANKQDLYQEIMAKAKAYKADRQREKMKHEEELNALDAHYKGILPS 232  

                   lamekltsRKsGiKkpreakedtDaeYDlllkEMvfe..kRAsPsdRTKT
                   l     +    GiK      + + +e D   k + +e++  A+ +dR+  
  gi|2398717   233 LKFRPNKYSIEGIKAANALSSEGPDEFDMISKQLMMEggHSAKAADRLMS 282  

                   eEElAqkEaekLreLEeeRlkRMeet....eEledgEeEiGGEESvkklk
                    EE A + a +L++LEe+R+ RM  ++++ eE  ++Ee++G  E      
  gi|2398717   283 SEEVALENAKRLEKLEEQRKNRMLNDepsvEESLEEEEDVGEGEEEEGEE 332  

                   vrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsd
                       +D+d+ f  E         e ++e    v+ +EddE + e +ed  
  gi|2398717   333 EEEEEDEDAAFDEEGGERDEVPEEAVEE-AAGVE-SEDDEEEEEDIEDTG 380  

                   DddsvndGtdlkqkKe..avLkddEneDDdLGAELEDkeGeeDd....Ee
                     d+     d + +    av + d + DD+      D    +D+ ++ Ee
  gi|2398717   381 KKDGGAVAADDNERLAmlAVDESDSDIDDE------DAQ-AVDEyttaEE 423  

                   DedEESDaEldvlkdLKedeaqplkgeaikasvke.KANmKKsadTiPAS
                      EE    +    +L      p    a  ++ +e+KA            
  gi|2398717   424 RVAEE-GTSVQYPTEL------PVGFDAFTNTASEdKA------------ 454  

                   LdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeNR
                       +pF   cP   +++  Ll   d    ++ V R i +h     ++  
  gi|2398717   455 ---GLPFSVSCPQDGDAMEKLLTTFDPLSRAKLVFRLIACHN---TPDE- 497  

                   KeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqel
                   ++    + v L  +    +  l+   i+       L     +Li la+++
  gi|2398717   498 RSEPRQLRVLLSSLF--SY--LADHEIRM------LPLIRAPLIDLARLM 537  

                   PeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsTS
                   P  +   +   l +     ++  + + + k+  +     + +v+  F T 
  gi|2398717   538 PDCATDYFTMNLIGA----YANSRRP-DAKAINM-----LHIVATVFQTT 577  

                   DfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRyv
                   D rH Vv Pal+l+ +      +   +d      L  +  +f    kRy 
  gi|2398717   578 DIRHRVVQPALMLLEQW-----ACCTQDMR----LLALLYEFLQPAKRYS 618  

                   PeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlfa
                   P+   ++q +      +             +                  +
  gi|2398717   619 PA---FFQLAGR---LM------------RCGTE---------------T 635  

                   vkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeive
                    +e  +l   r            +e + +      L i  v++       
  gi|2398717   636 EQETAKLLTRRVCMQA------GPEEKAG------LQI--VIQ------- 664  

                   iyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKlted
                     y  +            Lsr+ l      +                +  
  gi|2398717   665 -KYCPS------------LSRLVL----GPH----------------AR- 680  

                   akkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDp...DkeRs
                          L l   +P+a+++leP F   y     Pd     ++++D+   
  gi|2398717   681 -------LRLHAFRPIAVPSLEPVF---Y----DPDSAQSHIkgkDPILY 716  

                   elnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkiv
                   e  K+k++ K E++GA R l KDa+F   +R+    ak+ +     k+i 
  gi|2398717   717 ETQKMKRQYKQERRGAKRQLTKDASFLRHVRANDMQAKETAIQHDKKRIR 766  

                   nelqeqegAl<-*
                   + l e        
  gi|2398717   767 AALDESTNNY    776  

gi|255082726|ref|XP_002504349.1|: domain 1 of 1, from 1 to 578: score -113.2, E = 1.7
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                                           F  + +k KFdilGr   kvKg++G 
  gi|2550827     1    ---------------------FAMRSSKLKFDILGR---KVKGDKGN 23   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   +   R  +  kRk Tl +e + + Ks+af+D+R+GE +   +     Ee 
  gi|2550827    24 VLKAREAGYIKRKDTLLKEHQASGKSNAFVDRRFGEDDASMT----PEER 69   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGd.......rggsSvKD
                    + R  R r+ Q +        +n  l+D+ +dG + +++++  ++    
  gi|2550827    70 AIGRLARTRLRQIK----RGSGFN--LNDDDDDGQgyddeepITLTHGGK 113  

                   DlDsleelgee..........LsdddELadeaLDkdflalkrF..eeeDA
                    +D+ ee + + +   +++++  ddd  +d a+D+  + + +F+++e+D+
  gi|2550827   114 PIDEREEERRSahaiargrrgMRDDDSDDDMAMDAATTGALHFggGEDDD 163  

                   ...............eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeK
                   + +++ +++++++++e+ ++ r  +K+KkEVm+E I KSK  KaEra ++
  gi|2550827   164 gfeptlkrgdhdtpeENGDPNR--RKTKKEVMDELIDKSKYHKAERARQR 211  

                   eeveDlidkLDeNfkdLlsl.lamekltsRKsGiKkpreakedt..DaeY
                   e+ eDl dkLD+ fk +   +l    l       K     k+d+ +++ Y
  gi|2550827   212 ERDEDLLDKLDDEFKEISGAgLFRAALS------KGVGHLKPDGweRDDY 255  

                   DlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMeeteEl
                   D+l +E+ +e R++ +dR  T EE  + Ea+ L+  E  RlkRM++  E+
  gi|2550827   256 DKLARELALESRGQATDRIRTQEEVDAAEAATLETAERARLKRMNASDED 305  

                   edgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlleREDNv
                    d +e                +D+d               e     ED  
  gi|2550827   306 DDDDE----------------EDEDE--------------E-----EDAD 320  

                   dNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDdLGAEL
                   d eEd +d+    +++ +++ + +                          
  gi|2550827   321 DDEEDNDDEEAKEAEEAGEEKEEL-------------------------- 344  

                   EDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkgeaikasvkeKANm
                    D +    d  D+d  SD+E        e + + +++ a     k KA  
  gi|2550827   345 -DFS---GDKSDSDLWSDSE--------EQYEEGEPKPAKAKDPKAKA-- 380  

                   KKsadTiPASLdrsipFtidcPktheelleLlkkldleDkplIVeRIika
                         +P      +pFt+++P t  +l   +  l+ eD     eRI+k+
  gi|2550827   381 -----PVP-----ELPFTFPMPETPHDLEKIVGHLSVEDTTVALERIRKC 420  

                   hhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLv
                   h p Lke+N ++k+  F   LLq      E ls Q  +    ++ L  L 
  gi|2550827   421 HAPTLKEDN-RKKMQSFLGLLLQRF----EMLSGQSPLP---VDYLDVLA 462  

                   eaLielaqelPeklaislseellevikelaeeykknEhikyPSlkdLvfF
                         a   P ++  s++ +l+++  +l  + +   +  +P   + ++ 
  gi|2550827   463 VNIAAVANIVPFFAVTSARARLEKMAARLRQRLRDG-ETGWPPARTILLI 511  

                   kLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVL
                   +L + +F+T D+ H+V TPa l +  vL  + v+S               
  gi|2550827   512 SLFADIFPTTDKQHPVSTPAALYLGNVLAHCAVRS--------------- 546  

                   kfqsiSkRyvPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDsle
                                                                     
  gi|2550827     - -------------------------------------------------- -    

                   kGLPldnlfavkestllepqrLslaDLVtqtiteefpvdalrsSlLliKE
                                          + +                     +  
  gi|2550827   547 -----------------------TRE--------------------AV-- 551  

                   vleLvEeiveiyyklqAFiEIflPIlaLLsryslkeslpekRlkekllda
                         ++v + +++                   ++s p           
  gi|2550827   552 ------TAVVVAGLAA------------------RYSAPAG--------- 568  

                   velveKltedakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSy
                          +                P aI+ll                   
  gi|2550827   569 ------RIF---------------PEAITLL------------------- 578  

                   DpDkeRselnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerh
                                                                     
  gi|2550827     - -------------------------------------------------- -    

                   EKmkkivnelqeqegAl<-*
                                       
  gi|2550827     - -----------------    -    

gi|221116928|ref|XP_002161686.1|: domain 1 of 1, from 9 to 627: score -114.5, E = 1.7
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                       e  r+ K+  v  i+   NPF+++v+k K d+ G+   kvK ++G 
  gi|2211169     9    VENSRKKKRSSVPVIKR--NPFEIHVSKLKHDVIGK---KVKTDKGL 50   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                   PG SR ka ekRk+Tl +e+k++nK +++iD+R+GE ++  s     EeK
  gi|2211169    51 PGLSRSKANEKRKKTLLKEYKQRNKANVIIDRRFGEFDDTIS----AEEK 96   

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                   Ml Rf+ E+  Q+   K ++ynl+   +D e++++ g+     D+  +  
  gi|2211169    97 MLKRFTLEK--QRHHEKSSLYNLD--DDDEEDLTHYGQR--LADIQTFDD 140  

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqr..GAkKsKkEVm
                    g  L d+ E+ +        ++++F  +    e+  +++G k + + +m
  gi|2211169   141 AGLKLFDENEEENVH-----EHFGGFLTSKSPHEQSHKndGKKLTRQQIM 185  

                   eEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsG
                   +Ei+a SK  K Er+K +e    l+ kLD ++kd++sll   +++    G
  gi|2211169   186 DEIVANSKKKKFERQKTQEQTFELTQKLDSQYKDIQSLLI-QRPK----G 230  

                   iKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLre
                     k  ++k  +D+ YD+ +kE+vfe  A+ + R+K  EE+Aq E+ +L+e
  gi|2211169   231 SSKRDDIK--PDD-YDKTVKELVFEAKAQATNRLKSTEEIAQLEKFRLEE 277  

                   LEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKP
                   LE +R  RM+        +            +  S+d             
  gi|2211169   278 LEKQRQMRMNDNFI---DDN----------VTFLSADAIIE--------- 305  

                   KfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeav
                      + +        +dN  +    d      ++                 
  gi|2211169   306 --NYKK--------IDNRYEVRYNDGKMILPEG----------------- 328  

                   LkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqpl
                                    +  e + E D+d                  ++ 
  gi|2211169   329 -----------------ID-ENENESDDDQN----------------ESD 344  

                   kgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel.leLlkk
                    +  ++ s           dT                 + +e ++   ++
  gi|2211169   345 NENSVSTS----------GDT-----------------NDDEIeTGDDSD 367  

                   ldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlse
                      ++               L  +N     + F  vLL +    +    +
  gi|2211169   368 IYSDQESDM-----------LDKGN-----EHFFDVLLNYF--DY----V 395  

                   QdikknLNfqLLekLveaLielaqelPek.laislseellevikelaeey
                    d+ k+     L+ Lv+ L    q  P+++ +i +s +  +   +    y
  gi|2211169   396 CDMEKP----KLS-LVNDLSGQQQYVPYFkRGIVASVTDGGSLMKQIGHY 440  

                   kknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspv
                    k+Eh +                       H                   
  gi|2211169   441 TKPEHQMC--------------------YNHT------------------ 452  

                   sSlkdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVel
                          i l   ++VLk +   k++ P V    q+    ++      e 
  gi|2211169   453 -------IHLCVINVVLKKK---KKLTPMVLGYDQG----YSDN----ED 484  

                   lsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtit
                     ++  +  +     l   LP  n+ + ++ +++e               
  gi|2211169   485 RTEVGDDIKKK----LLMQLPVSNDDELQP-NIIEKFGKN---------- 519  

                   eefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsrys
                      ++  ++s   ++  ++  +E + e+             I    +++ 
  gi|2211169   520 ---KSLICDSRTKSS-STIDMLEHFLEVQPEVK--------IAMIVQQLI 557  

                   lkeslpekRlkekllda.velveKltedakkerKPLAlqeHKPvaIrlle
                   l  + p + +k  +   ++ lv K+++                       
  gi|2211169   558 LFIEQPDTEMKLDHQEIgTNLVQKKIA----------------------- 584  

                   PKFEEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDak
                        ++       k                           R +  D  
  gi|2211169   585 -----VF----EASKA--------------------------RPMYLDLL 599  

                   FvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                   F a + +  +  +         ++   l  +   +   
  gi|2211169   600 FKALQTIPPTSVE-------AERAFSSLGFFATKI    627  

gi|239888371|gb|EER11103.1|: domain 1 of 1, from 11 to 774: score -119.2, E = 1.8
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFd.ilGrsKtkvKgeeG
                      ++ dr+          + fN Fd +++k  ++++lG       g ++
  gi|2398883    11    SSRDRQRP-----SDGSGFNQFDMRANKTARKpVLGM--AQQHGSRR 50   

                   kPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEe
                     + S+  a   Rk  l +ef    K+g f+D+R   +    s      e
  gi|2398883    51 NMSESKSYAKTSRKDSLLKEFRALGKTGSFKDRRLDAKAQGMS----ADE 96   

                   KMleRfsRErmSQlrLSKreaynlnDGlEDvee............dGdrg
                      +Rf  Er+ Q   SK++ +    GlED ee++++ ++ +++ +++ g
  gi|2398883    97 LASARFRKERIRQQEKSKKKRNAAF-GLEDEEEgegsaegvehnlLTHGG 145  

                   gsSvKDDlDsleelgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeq
                              +   +eL  d + +++  D+ ++      e  Ae+ +  
  gi|2398883   146 K-------PVKTMTADELRGDPLSDSDD-DEELK-----KEIEAELMKTT 182  

                   r.GAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsl
                   ++G +  K+    Ei aK K yKa r+ eK + e +   LD+ +k +l++
  gi|2398883   183 EhGKHANKQDLYQEIMAKAKAYKADRQREKMKHEEELNALDAHYKGILPS 232  

                   lamekltsRKsGiKkpreakedtDaeYDlllkEMvfe..kRAsPsdRTKT
                   l     +    GiK      + + +e D   k + +e++  A+ +dR+  
  gi|2398883   233 LKFRPNKYSIEGIKAANALSSEGPDEFDMISKQLMMEggHSAKAADRLMS 282  

                   eEElAqkEaekLreLEeeRlkRMeet....eEledgEeEiG.GEESvkkl
                    EE A + a +L++LEe+R+ RM  ++++ eE  ++Ee++G+GEE     
  gi|2398883   283 SEEVALENAKRLEKLEEQRKNRMLNDepsvEESLEEEEDVGeGEEEEGEE 332  

                   kvrSvdDLdDsfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaeds
                        +D+d+ f  E         e ++e    v+ +EddE + e +ed 
  gi|2398883   333 EE---EDEDAAFDEEGGERDEVPEEAVEE-AAGVE-SEDDEEEEEDIEDT 377  

                   dDddsvndGtdlkqkKe..avLkddEneDDdLGAELEDkeGeeDd....E
                      d+     d + +    av + d + DD+      D    +D+ ++ E
  gi|2398883   378 GKKDGGAVAADDNERLAmlAVDESDSDIDDE------DAQ-AVDEyttaE 420  

                   eDedEESDaEldvlkdLKedeaqplkgeaikasvke.KANmKKsadTiPA
                   e   EE    +    +L      p    a  ++ +e+KA           
  gi|2398883   421 ERVAEE-GTSVQYPTEL------PVGFDAFTNTASEdKA----------- 452  

                   SLdrsipFtidcPktheelleLlkkldleDkplIVeRIikahhpKLkeeN
                        +pF   cP   +++  Ll   d    ++ V   i +h     ++ 
  gi|2398883   453 ----GLPFSVSCPQDGDAMEKLLTTFDPLSRAKLVFSLIACHN---TPDE 495  

                   RKeklvKFsvvLLqhIKDLfEDlseQdikknLNfqLLekLveaLielaqe
                    +     + v L  +    +  l+   i+       L     +Li la++
  gi|2398883   496 -RFEPRQLRVLLSSLF--SY--LADHEIRM------LPLIRAPLIDLARL 534  

                   lPeklaislseellevikelaeeykknEhikyPSlkdLvfFkLvgllFsT
                   +P  +   +   l +     ++  + + +  +  +     + +v+  F T
  gi|2398883   535 MPDCATDYFTMNLIGA----YANSRRP-DARAINM-----LHIVATVFQT 574  

                   SDfrHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsiVLkfqsiSkRy
                    D rH Vv Pal+l+ +      +   +d      L  +  +f    kRy
  gi|2398883   575 TDIRHRVVQPALMLLEQW-----ACCTQDMR----LLALLYEFLQPAKRY 615  

                   vPeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGLPldnlf
                    P+   ++q +      +             +                  
  gi|2398883   616 SPA---FFQLAGR---LM------------RCGTE--------------- 632  

                   avkestllepqrLslaDLVtqtiteefpvdalrsSlLliKEvleLvEeiv
                   + +e  +l   r            +e + +      L i  v++      
  gi|2398883   633 TEQETAKLLTRRVCMQA------GPEEKAG------LQI--VIQ------ 662  

                   eiyyklqAFiEIflPIlaLLsryslkeslpekRlkeklldavelveKlte
                      y  +            Lsr+ l      +                + 
  gi|2398883   663 --KYCPS------------LSRLVL----GPH----------------AR 678  

                   dakkerKPLAlqeHKPvaIrllePKFEEnyDDKRsPdksSyDp...DkeR
                           L l   +P+a+++leP F   y     Pd     ++++D+  
  gi|2398883   679 --------LRLHAFRPIAVPSLEPVF---Y----DPDSAQSHIkgkDPIL 713  

                   selnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkki
                    e  K+k++ K E++GA R l KDa+F   +R+    ak+ +     k+i
  gi|2398883   714 YETQKMKRQYKQERRGAKRQLTKDASFLRHVRANDMQAKETAIQHDKKRI 763  

                   vnelqeqegAl<-*
                    + l e        
  gi|2398883   764 RAALDESTNNY    774  

gi|195099677|ref|XP_001997981.1|: domain 1 of 1, from 1 to 339: score -158.4, E = 3.1
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                                                                     
  gi|1950996     -    ----------------------------------------------- -    

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKf
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   GfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLk
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   ddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplkg
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   eaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkldl
                                                                     
  gi|1950996     - -------------------------------------------------- -    

                   eDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQdi
                                                           +fED+seQdi
  gi|1950996     1 ----------------------------------------MFEDASEQDI 10   

                   kknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykknE
                   +++  fqLL  L+++ + l+q++Pe+    +s++ll+vike+++ey+kn 
  gi|1950996    11 LSH--FQLLAQLMPHMYDLTQLNPER----MSNTLLDVIKEKYAEYRKN- 53   

                   hikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlk
                   h+ yPSl++L++FkLv++l+sTSDfrH+V TP  ++m++ Lsr ++++++
  gi|1950996    54 HKVYPSLDTLIYFKLVSNLYSTSDFRHPVATPTYIFMQHILSRARIRTRQ 103  

                   dIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVe.llsi
                   dIa+GlfLv+i  +f s SkR++P+V+++l +iL+ + +pKR  e++  i
  gi|1950996   104 DIAMGLFLVNIAMEFGSRSKRLLPAVFNFLLGILH-MVIPKRQTEdQYDI 152  

                   tPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteef
                   +P +Ferd  ++++k   l++++a kes  lepq+L+ aDLVt t t +f
  gi|1950996   153 VP-PFERD--GPFSK---LLAIPATKESQALEPQQLQAADLVTHTFTLDF 196  

                   pvdalrsSlLliKE.vleLvEeiveiyyklqAFiEIflPIlaLLsryslk
                   +v+a ++ l liK   +eLv e+++++y++        P+l LL r++l 
  gi|1950996   197 KVRAVDATLRLIKNiFEELVGEHIGACYLAN-------PFLPLLERLPL- 238  

                   eslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKF
                   + +pe+ ++e++  a  ++    +   +++K LA++ +KP+a+rlleP+F
  gi|1950996   239 KHYPEH-VQEHHAAAKSALQQVSA---QKMKRLAPADKKPKALRLLEPRF 284  

                   EEnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFva
                   E +yDDKR+P++s     k ++e++KL++k+KrEkKGAiRE+R+D+ Fv+
  gi|1950996   285 EVVYDDKRRPKMS-----KQKEERAKLLHKIKREKKGAIREIRRDTAFVQ 329  

                   rlRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                    l+lk++ +                          
  gi|1950996   330 DLKLKQQIQR----------------------    339  

gi|33874764|gb|AAH09760.2|: domain 1 of 1, from 1 to 468: score -191.2, E = 4.7
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                                                                     
  gi|3387476     -    ----------------------------------------------- -    

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                                                                     
  gi|3387476     - -------------------------------------------------- -    

                   MleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDslee
                        +++r                                         
  gi|3387476     1 -----QAQR--------------E-------------------------- 5    

                   lgeeLsdddELadeaLDkdflalkrFeeeDAeaeeeqrGAkKsKkEVmeE
                               d+                       +            
  gi|3387476     6 ------------DAL----------------------E------------ 9    

                   iIaKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekltsRKsGiK
                                        l++kLD   k ++ ll+   +t  Ks   
  gi|3387476    10 ---------------------LTEKLDQDWKEIQTLLS--HKT-PKSENR 35   

                   kpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLE
                   +  e k+ +Da YD  ++E+ fe  A+Ps R KTe ElA++E e Lr+LE
  gi|3387476    36 DKKE-KPKPDA-YDMMVRELGFEMKAQPSNRMKTEAELAKEEQEHLRKLE 83   

                   eeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsfsVE.EDKPK
                    eRl+RM +  E    +e       vkk+k+ S+dDL D f  +++D+  
  gi|3387476    84 AERLRRMLGKDE----DE------NVKKPKHMSADDLNDGFVLDkDDRRL 123  

                   fGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavL
                     + ++    E+ v  e + E  d e+ ++++    ++G+          
  gi|3387476   124 LSYKDGKMNVEEDVQEEQSKEASDPESNEEEG---DSSGG---------- 160  

                   kddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLKedeaqplk
                   +d E++D        D      d e  +E+   E ++ k  Ke    p k
  gi|3387476   161 EDTEESDSP------DSH---SDLESNVES---EEENEKPAKEQRQTPGK 198  

                   geaikasvkeKANmKKsadTiPASLdrsipFtidcPktheelleLlkkld
                   g    +s+ke A   K            +p+t+  P ++eel  Ll + +
  gi|3387476   199 GL---ISGKERA--GKATRD-------ELPYTFAAPESYEELRSLLLGRS 236  

                   leDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDLfEDlseQd
                    e   l+VeRI k++hp L+e+N K kl+K+  +LL ++     Dl+  d
  gi|3387476   237 MEEQLLVVERIQKCNHPSLAEGN-KAKLEKLFGFLLEYV----GDLATDD 281  

                   ikknLNfqLLekLveaLielaqelPeklaislseellevikelaeeykkn
                         +    kLv +L+ l q +Pe +      +l++   e+ e +   
  gi|3387476   282 PPD---LTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMHEMEEMIETK 328  

                   EhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSl
                        P l+ L+++k++gllF+TSDf H+VvTPal  +++ L ++p+ Sl
  gi|3387476   329 GRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQLLTKCPILSL 378  

                   kdIaiGlfLvsiVLkfqsiSkRyvPeVvyalqqiLftllvpKRDVellsi
                   +d+ +Glf + ++L+++  S R++Pe++++l +iL+   +          
  gi|3387476   379 QDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILY---IA--------- 416  

                   tPLtFerdRLDslekGLPldnlfavkestllepqrLslaDLVtqtiteef
                   tP                    +a + stl+ p r               
  gi|3387476   417 TP-----N--------------KASQGSTLVHPFRALGKN---------- 437  

                   pvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflPIlaLLsryslke
                         s lL +        e v  +   +               +sl  
  gi|3387476   438 ------SELLVV-----SAREDVATWQQSS---------------LSL-- 459  

                   slpekRlkeklldavelveKltedakkerKPLAlqeHKPvaIrllePKFE
                      ++                                             
  gi|3387476   460 -RWSR--------------------------------------------- 463  

                   EnyDDKRsPdksSyDpDkeRselnKLkaklKrEkKGAiRElRKDakFvar
                           Pd                                        
  gi|3387476   464 -------IPDLR-------------------------------------- 468  

                   lRlkEkaakdqerhEKmkkivnelqeqegAl<-*
                                                     
  gi|3387476     - -------------------------------    -    

gi|66361603|ref|XP_627325.1|: domain 1 of 1, from 40 to 959: score -212.4, E = 6.3
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdil......GrsKtkv
                      + + r+ K          fN  d+ +  rK+ il++  ++Gr K   
  gi|6636160    40    SLDKRKDK--------LGFN--DRDFLERKRSILkelyseGR-KSEF 75   

                   KgeeGkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGD
                     e+ k    R   +    +Tl a ++ k K    + kR   +n  L   
  gi|6636160    76 NDEREKFAL-RKDSIGDNYQTLIATKQLKKK----VKKR--KNNFNLD-- 116  

                   qLeEeKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDD
                     eEe     + R        S  +++n +   +D +e ++ g s    D
  gi|6636160   117 --EEEDDDNDY-RGH------SGENLNNTS--TND-LEFTHQGKSISALD 154  

                   lDsleelgeeLsdddELadea..........LDkdfl...alkrFeeeDA
                      + +++   ++d   +d   ++++++++ LD+  +++  ++  + ++ 
  gi|6636160   155 DKAIRKYDGNIDEDNDFDDNDytgsrkgdsiLDEKNMpgfFFGQGNSDGT 204  

                   eaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKeeveDlidkLDeNfk
                   +   +q+        + +Ei  KSKl K+E    +e  e +  +LD  f 
  gi|6636160   205 STKSRQE--------IFKEIMQKSKLAKMEMKRHRESLEEELVNLDSAFS 246  

                   dLlsllamekltsRK.......................sGiKkpreaked
                    ++s l+   + sRK++ ++  ++ +++++ +++++++  i      +e 
  gi|6636160   247 QVQSMLS--YKQSRKdrvnsllnninsnssvtdnngndNNIQSSDKNIEE 294  

                   tDaeYDlllkEMvfekRAsPsdRTKTeEElAqkEaekLreLEeeRlkRMe
                   +D  Y  l + + f+ R  +sdR KT EE+A+  aekL+ LE eR++RM+
  gi|6636160   295 LDE-YEQLRNLLKFDTRTGVSDRIKTDEEIAKLNAEKLERLEKERKERMN 343  

                   eteEledgEeEiGGEESvkklkvrSvdDLdDsfsVEEDKPKfGfiedlle
                    +    d +       S+        dD dD +  EED    Gf +  +e
  gi|6636160   344 LDDSNIDIDL------STESENEYFKDDFDDEDGEEED----GFED--EE 381  

                   REDNvdNeEddEdddeeaedsdDddsvndGtdlkqkKeavLkddEneDDd
                    ED  + eE+ E + ee e+++ ++ +    d+  k e    + E+eD +
  gi|6636160   382 -EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEDEGRKVEKDCFEEEEEDGE 430  

                   LGAELEDkeGeeDdEeDe.......dEESDaEldvlkdLKedeaqplkge
                        E + Ge+D+E+ ++ +++  d+E   E+d    L +de++p    
  gi|6636160   431 ----GEEEDGEDDEERVKpaskgfiDFE-LNEIDEIDWLVNDESEP---- 471  

                   aikasvkeKANmKKsadTiPASLdrsipFtidc.PktheelleLlkkldl
                   ++  s     N+KK       SL   + F+   +Pk+   ++     + +
  gi|6636160   472 NLPFS----VNLKKILKE--YSLKGLMEFMNGFsPKSQWKFICRFRSCFN 515  

                   e.......DkplIVeRIik..ahhpKLkeeNRKeklvKFsvv...LL...
                   ++++   +D  l +   ik +++    +e    ek   F ++ + L+  +
  gi|6636160   516 KgdtamlnDLKLLIGFLIKypLNCLRTAESD-SEKKNIFQFIinyLKlms 564  

                   qhIKDLfEDlseQdikknL......NfqLLekLveaLielaqelPeklai
                    h+  Lf  ++e d k+ L   +   f+    + +  +   ++   +l+ 
  gi|6636160   565 SHL--LF--MAETDPKECLiiftyfTFEICHTTFPSVYHKYKKVEKFLND 610  

                   slsee.llevikelaee....ykknEhikyPSlkdLvfFkLvgllFsTSD
                    l +++ + +  e  ee ++ y   E+i  + l+  v  +++ +lF+  D
  gi|6636160   611 NLLNVeNENYYTEILEEcpslYQLSEDIYELTLEHIVICRMMFILFPVTD 660  

                   frHlVvTPalllmaevLsrspvsSlkdIaiGlfLvsi....VLkfqsiSk
                     H++ TP+++ + +   r      + + + l   + ++++  +f+    
  gi|6636160   661 AQHPILTPVIICLEQWAHR-----WSQVGKSLLNTNTpdqdSEEFKYNQI 705  

                   Ryv....PeVvyalqqiLftllvpKRDVellsitPLtFerdRLDslekGL
                   R+v++++P++   +  i + l +        si     ++    s   G 
  gi|6636160   706 RLVggsnPNISCMIGVICL-LEIS-------SIGY---ANS--KSNNNGN 742  

                   Pldnlfavkestl....lepqrLslaDLVtqtiteefpvdalrsSlLliK
                    l+  f +   tl+ + l+   Ls  D     i+ e +   l   +L + 
  gi|6636160   743 ELLERFSIGYFTLslscLKWLLLSDPD---NNISIEEKRISLSIGILKS- 788  

                   EvleLvEeiveiyyklqAFiEIflP.IlaLLsry..slkeslpekRlkek
                        +   + +++ lq F  I++  I +   ++++sl + +  k +  +
  gi|6636160   789 -----LIRVISAFKDLQGFHAIIIHlIRENIKQIneSLMKMDNCK-VLLN 832  

                   lldavelveKltedakkerKPLAlqeHKPvaIrllePKFEE...nyDDKR
                   l + +e ++  ++   +  KP +l  +    Ir+l PK   ++  +  K 
  gi|6636160   833 LVSEIESISTEIA--NRPQKPISLCPRQTPTIRSLIPKIDDpsvPFAAKA 880  

                   sPdksSyDpDkeRselnK......LkaklKrEkKGAiRElRKDakFvarl
                    +  + + p     e  K++  ++Lk+    +++ A R lRKD++ +a  
  gi|6636160   881 MLRAK-HGPKESQYEHEKkhylsrLKKEVNTARRQASRQLRKDSQVIASA 929  

                   RlkEkaakdqerhEKmkkivnelqeqegAl<-*
                     + +  k+   ++K       l   + +    
  gi|6636160   930 WHENRTEKSNKQNAKYNSFMKMLEDDQAEY    959  

gi|67594925|ref|XP_665952.1|: domain 1 of 1, from 20 to 963: score -213.6, E = 6.3
                   *->keedreeKKKAvakiqkefNPFdvkvakrKFdilGrsKtkvKgeeGk
                      k  d   K   v k +      +    krK + +      +   e+k
  gi|6759492    20    KKKDPHLK---VIKSRNSSKI-ENSLDKRKDKLGFN---DRDFLERK 59   

                   PGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeEeK
                    ++ +    e Rk  +  e +k   +  f    iG +   L         
  gi|6759492    60 RSILKELYSEGRKSEFNDEREKFALRKDF----IGDNYQTLI-------- 97   

                   MleRfsRErmSQlrLSKreaynlnDGlED...................ve
                      R +  +   ++   ++  nl++ +ED+++ ++ ++++ +++++++++
  gi|6759492    98 -ATRQLKKK---VK-KRKNNFNLDEEEEDdndyrgysgenfknntstnDL 142  

                   edGdrggsSvKDDlDsleelgeeLsdddELadea..........LDkdfl
                   e ++ g s    D   + +++   ++d   +d   ++++++++ LD+  +
  gi|6759492   143 EFTHQGKSISALDDKAIRKYDGNIDEDNDFDDNDytgnrkgdsiLDEKNM 192  

                   ...alkrFeeeDAeaeeeqrGAkKsKkEVmeEiIaKSKlyKaEraKeKee
                   ++  ++  + ++ +   +q+        + +Ei  KSKl K+E    +e 
  gi|6759492   193 pgfFFGQGNSDGTSTKSRQE--------IFKEIMQKSKLAKMEMKRHRES 234  

                   veDlidkLDeNfkdLlsllamekltsRK......................
                    e +  +LD  f  ++s l+   + sRK++ ++  ++ +++++ ++++++
  gi|6759492   235 LEEELVNLDNAFSQVQSMLS--YKQSRKdrvnsllnninsnssvtdnnsn 282  

                   .......sGiKkpreakedtDaeYDlllkEMvfekRAsPsdRTKTeEElA
                   +++++++  i      +e +D  Y  l + + f+ R  +sdR KT EE+A
  gi|6759492   283 dnnnnnnNNIRSFDKNIEELDE-YEQLRNLLKFDTRTGVSDRIKTDEEIA 331  

                   qkEaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdD
                   +  aekL+ LE eR++RM+ +    d +       S+        dD dD
  gi|6759492   332 KLNAEKLERLEKERKERMNLDDSNIDIDL------STESENEYFKDDFDD 375  

                   sfsVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGt
                    +  EED    Gf e  +e       eE  E++ ee e+++ ++ +    
  gi|6759492   376 EDGEEED----GFEE--EE------EEEKEEGEEEEEEEEEEEEEEEE-E 412  

                   dlkqkKeavLkddEneDDdLGAELEDkeGeeDdEeDe.......dEESDa
                   d+ qk e    + E+eD + G E + + Ge D+E+ ++ +++  d+E   
  gi|6759492   413 DEEQKVEEDCFEEEEEDGE-GEEEDGEDGENDEERVKpaskgfiDFE-LN 460  

                   EldvlkdLKedeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFti
                   E++    L +de++p    ++  s     N+KK       SL   + F+ 
  gi|6759492   461 EIEEIDWLLNDESEP----NLPFS----VNLKKILKE--YSLKGLMEFMN 500  

                   dc.PktheelleLlkkldleDkplIVe..RIikahhpKL........kee
                     +Pk+   ++     + ++      ++ +  + + +K + +  ++ + +
  gi|6759492   501 GFsPKSQWKFICRFRSCFNKGDTAMLNdlKLLIGFLIKYplnclrsaESD 550  

                   NRKeklvKFsvvLLq....hIKDLfEDlseQdikknL......NfqLLek
                     K+++  F    L+  ++h+  Lf  ++e d k+ L   +   f+    
  gi|6759492   551 SEKKNIFQFIINYLKlmssHL--LF--MAETDPKECLiiftyfTFEICHT 596  

                   LveaLielaqelPeklaislsee.llevikelaee....ykknEhikyPS
                   + +  +   ++   +l+  l +++ + +  e  ee ++ y   E+i  + 
  gi|6759492   597 TFPSVYHKYKKVEKFLNNDLLNVeNENYYTEILEEcpslYQLSEDIYELT 646  

                   lkdLvfFkLvgllFsTSDfrHlVvTPalllmaevLsrspvsSlkdIaiGl
                   l+  v  +++ +lF+  D  H++ TP+++ + +   r      + + + l
  gi|6759492   647 LEHIVICRMMFILFPVTDAQHPILTPVIICLEQWAHR-----WSQVGKSL 691  

                   fLvsi....VLkfqsiSkRyv....PeVvyalqqiLftllvpKRDVells
                      + ++++  +f+    R+v++++P++   +  i + l +        s
  gi|6759492   692 LNTNTpdqdSEEFKYNQIRLVggsnPNISCMIGVICL-LEIS-------S 733  

                   itPLtFerdRLDslekGLPldnlfavkestl....lepqrLslaDLVtqt
                   i     ++    s   G  l+  f +   tl+ + l+   Ls  D     
  gi|6759492   734 IGY---ANS--KSNNNGNELLERFSIGYFTLslscLKWLLLSDSD----- 773  

                   iteefpvdalrsSlLliKEvleLvEeiveiyyklqAFiEIflP.IlaLLs
                        + d  + S L+i  +l  +   + +++ lq F  I++  I +   
  gi|6759492   774 --NNISIDEKKIS-LSI-GILKSLIRVISAFKDLQGFHAIIIHlIRENIK 819  

                   ry..slkeslpekRlkeklldavelveKltedakkerKPLAlqeHKPvaI
                   ++++sl + +  k +  +l + +e ++  ++   +  KP +l  +    I
  gi|6759492   820 QIneSLIKMDNCK-VLLNLVSEIESISTEIA--NRPQKPISLCPRQTPTI 866  

                   rllePKFE.........EnyDDKRsPdksSyDpDkeRselnKLkaklKrE
                   r+l PK  +++ +   ++    K sP+ s y   k +  l  Lk+    +
  gi|6759492   867 RSLIPKIDdpsvpfaakAMLRAKHSPKESQYEHEK-KHYLSRLKKEVNTA 915  

                   kKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivnelqeqegAl<-
                   ++ A R lRKD+  +a    + +  k+   ++K       l   + +   
  gi|6759492   916 RRQASRQLRKDSHVIASAWHENRTEKSNKQNAKYNSFMKMLEDDQAEY   963  

                   *
                    
  gi|6759492     -   -    

gi|71746130|ref|XP_822264.1|: domain 1 of 1, from 170 to 897: score -238.4, E = 8.8
                   *->keedreeKKKAv..akiqkefNPFdvkvakrKFdilGrsKtkvKgee
                        edree   A ++ak+       + + + +  +  +    + + e+
  gi|7174613   170    AAEDREEGGLAAppAKVTRAERFREMISNSKGQRAQLQ---RERAER 213  

                   GkPGVSRakaeekRkrTleaefkkknKsgafiDkRiGErnkhLsGDqLeE
                       V     +      l ++ k k    af      E   +L       
  gi|7174613   214 DATTVQLDAEINSLLHLLPKRNKAKEEQEAFAQSGTPEVRALLD------ 257  

                   eKMleRfsRErmSQlrLSKreaynlnDGlEDveedGdrggsSvKDDlDsl
                         + R    Q +     + + + G+  v ++ d   s         
  gi|7174613   258 -----SYRRNH--QAK----CLTLKSSGAFEVRTLVDAARS-------TT 289  

                   eelgeeLsdddELadeaLDkdflalkrFee..eDAeaeeeqrGAkKsKkE
                     +  + +  d  a ++    + a+  F +  + A +   ++GA  s   
  gi|7174613   290 NRSAPSAQTADPTAPAS-ATARDAAPSFLDaaDRALLARVRAGAACSSED 338  

                   VmeEiI....aKSKlyKaEraKeKeeveDlidkLDeNfkdLlsllamekl
                    + E+ ++ +a      + r+++ ++ e                 am  +
  gi|7174613   339 GINEVAstagARVGAPSMPRQAAADIAEAR---------------AMVIP 373  

                   tsRKsGiKkpreakedtDaeYDlllkEMvfek.RAsPsdRTKTeEElAqk
                             r+a    D+  Dl     +++++RA+  dRT TeEE A+k
  gi|7174613   374 G------GGGRPAS--CDD-FDLMMHTFQMDPrRAHAVDRTLTEEEEAAK 414  

                   EaekLreLEeeRlkRMeeteEledgEeEiGGEESvkklkvrSvdDLdDsf
                    a      E+       + +E  d    +   E v++   +     dD  
  gi|7174613   415 SAQQTLLKEDREQVPLLHLQE-RDQTQ-LTRGEWVAQGGDIAFHMDDDAE 462  

                   sVEEDKPKfGfiedlleREDNvdNeEddEdddeeaedsdDddsvndGtdl
                   +        G  +     EDNvd   ++E+d +   dsd           
  gi|7174613   463 NA-------G-AD-----EDNVDIPSSYEGDSDADVDSDE---------- 489  

                   kqkKeavLkddEneDDdLGAELEDkeGeeDdEeDedEESDaEldvlkdLK
                                      A +   e   +dEeD   E            
  gi|7174613   490 ------------------AAVVAESE-LGEDEEDAAVE------------ 508  

                   edeaqplkgeaikasvkeKANmKKsadTiPASLdrsipFtidcPktheel
                              +++s    A                         t + l
  gi|7174613   509 ----------RVSGS----A-------------------------TLDRL 519  

                   leLlkkldleDkplIVeRIikahhpKLkeeNRKeklvKFsvvLLqhIKDL
                    e+l+  ++                  + eN  ++   + + L q    L
  gi|7174613   520 FEQLEQVATS-----------------ETENATSRPQRLHALLVQ----L 548  

                   fEDlseQdikknLNfqLLekLveaLielaqelPeklaislseellevike
                   +       +  +           +  e ++ +   l    ++ l++++  
  gi|7174613   549 H------RYAAH-----------HVVEVTKAFRFVLVEAERSFLRGTRR- 580  

                   laeeykknEhikyPSlkdLvfFkLvgllFsTSDfrHlVvTPalllmaevL
                             ++  Sl  Lv++  ++ +F+TSD rH+V+TP ll+++  L
  gi|7174613   581 ---------GGMRRSL--LVYLYAISKIFPTSDYRHAVMTPFLLFLCSAL 619  

                   srspvsSlkdIaiGlfLvsiVLk.fqsiSkRyvPeVvyalqqiLftllvp
                   ++ + +Sl  +   l+L+++ L   +  S R+  eVv a    L  l  p
  gi|7174613   620 MQMKLDSLEAVHSYLVLATLLLHcLKAGSGRFCAEVVVAALNVLA-LQLP 668  

                   KRDVellsitPLtFerdRLDslekGLPldnlfavkestllepqrLslaDL
                           + P  +    + +  +   l+       ++     +Ls  D 
  gi|7174613   669 -----RVALEPARYQGT-VLPMPL---LERTEQALLVSSAAAATLSESD- 708  

                   VtqtiteefpvdalrsS.....lLliKEvleLvEeiveiyyklqAFiEI.
                    t    + + v+++++ +++++lLl   +  L+Ee  +   + +AF+   
  gi|7174613   709 DTTSQRPPYQVGLFDTThsperLLLC--AYRLLEEVCDLHRSTPAFPVMc 756  

                   ...flPIlaLLsryslke.......slpekRlkeklldavelveKlteda
                    ++fl   aLL r ++    +  ++s p +  +e l  +v    K  e  
  gi|7174613   757 arpFLALDALLLRPPSSSaasawtpSVPVRLAHEVLTVKVRDMAKHVE-- 804  

                   kkerKPLAlqeHKPvaIrllePKF...EEnyDDKRsPdksSyDpDkeRse
                      r PLA++  +P  +r   P   ++EEn                ++ e
  gi|7174613   805 -EHRTPLAMRTFRPRPLRQFDPLLaerEENA---------------AKTE 838  

                   lnKLkaklKrEkKGAiRElRKDakFvarlRlkEkaakdqerhEKmkkivn
                      +k+ ++  kK  iR l   a    r   k  a  d  r      +  
  gi|7174613   839 VRLMKRDIREDKKRLIRHLTAEATVQRRAQEKRHAITDALREKRYHNVMS 888  

                   elqeqegAl<-*
                   +lq q++ +   
  gi|7174613   889 QLQQQQHSM    897  


Histogram of all scores:
score    obs    exp  (one = represents 456 sequences)
-----    ---    ---
-1171      1      0|=                                                          
-1170      1      0|=                                                          
-1169      1      0|=                                                          
-1168      1      0|=                                                          
-1167      3      0|=                                                          
-1166      3      0|=                                                          
-1165      4      0|=                                                          
-1164      4      0|=                                                          
-1163     17      0|=                                                          
-1162     26      0|=                                                          
-1161     71      0|=                                                          
-1160     94      0|=                                                          
-1159    170      0|=                                                          
-1158    203      0|=                                                          
-1157    280      0|=                                                          
-1156    299      0|=                                                          
-1155    329      0|=                                                          
-1154    410      0|=                                                          
-1153    439      0|=                                                          
-1152    445      0|=                                                          
-1151    537      0|==                                                         
-1150    495      0|==                                                         
-1149    614      0|==                                                         
-1148    573      0|==                                                         
-1147    574      0|==                                                         
-1146    570      0|==                                                         
-1145    623      0|==                                                         
-1144    622      0|==                                                         
-1143    642      0|==                                                         
-1142    686      0|==                                                         
-1141    693      0|==                                                         
-1140    705      0|==                                                         
-1139    710      0|==                                                         
-1138    808      0|==                                                         
-1137    845      0|==                                                         
-1136    810      0|==                                                         
-1135    908      0|==                                                         
-1134    945      0|===                                                        
-1133   1013      0|===                                                        
-1132   1044      0|===                                                        
-1131   1067      0|===                                                        
-1130   1135      0|===                                                        
-1129   1127      0|===                                                        
-1128   1180      0|===                                                        
-1127   1244      0|===                                                        
-1126   1282      0|===                                                        
-1125   1216      0|===                                                        
-1124   1280      0|===                                                        
-1123   1404      0|====                                                       
-1122   1515      0|====                                                       
-1121   1483      0|====                                                       
-1120   1620      0|====                                                       
-1119   1566      0|====                                                       
-1118   1645      0|====                                                       
-1117   1644      0|====                                                       
-1116   1820      0|====                                                       
-1115   1894      0|=====                                                      
-1114   2032      0|=====                                                      
-1113   2073      0|=====                                                      
-1112   2271      0|=====                                                      
-1111   2193      0|=====                                                      
-1110   2348      0|======                                                     
-1109   2381      0|======                                                     
-1108   2543      0|======                                                     
-1107   2703      0|======                                                     
-1106   2851      0|=======                                                    
-1105   2945      0|=======                                                    
-1104   3052      0|=======                                                    
-1103   3417      0|========                                                   
-1102   3530      0|========                                                   
-1101   3772      0|=========                                                  
-1100   4042      0|=========                                                  
-1099   4205      0|==========                                                 
-1098   4279      0|==========                                                 
-1097   4299      0|==========                                                 
-1096   4472      0|==========                                                 
-1095   4509      0|==========                                                 
-1094   4720      0|===========                                                
-1093   5032      0|============                                               
-1092   5222      0|============                                               
-1091   5431      0|============                                               
-1090   5832      0|=============                                              
-1089   5973      0|==============                                             
-1088   6232      0|==============                                             
-1087   6739      0|===============                                            
-1086   6792      0|===============                                            
-1085   7229      0|================                                           
-1084   7282      0|================                                           
-1083   7636      0|=================                                          
-1082   8002      0|==================                                         
-1081   8019      0|==================                                         
-1080   8197      0|==================                                         
-1079   8543      0|===================                                        
-1078   8541      0|===================                                        
-1077   8470      0|===================                                        
-1076   8792      0|====================                                       
-1075   8713      0|====================                                       
-1074   8704      0|====================                                       
-1073   8663      0|===================                                        
-1072   8872      0|====================                                       
-1071   8820      0|====================                                       
-1070   8853      0|====================                                       
-1069   9101      0|====================                                       
-1068   9229      0|=====================                                      
-1067   9206      0|=====================                                      
-1066   9256      0|=====================                                      
-1065   9515      0|=====================                                      
-1064   9427      0|=====================                                      
-1063   9520      0|=====================                                      
-1062   9710      0|======================                                     
-1061   9919      0|======================                                     
-1060   9727      0|======================                                     
-1059   9903      0|======================                                     
-1058   9910      0|======================                                     
-1057  10053      0|=======================                                    
-1056  10263      0|=======================                                    
-1055  10165      0|=======================                                    
-1054  10128      0|=======================                                    
-1053  10468      0|=======================                                    
-1052  10704      0|========================                                   
-1051  10620      0|========================                                   
-1050  10591      0|========================                                   
-1049  10660      0|========================                                   
-1048  10819      0|========================                                   
-1047  10801      0|========================                                   
-1046  11065      0|=========================                                  
-1045  11251      0|=========================                                  
-1044  11283      0|=========================                                  
-1043  11406      0|==========================                                 
-1042  11481      0|==========================                                 
-1041  11480      0|==========================                                 
-1040  11692      0|==========================                                 
-1039  11615      0|==========================                                 
-1038  11775      0|==========================                                 
-1037  11880      0|===========================                                
-1036  12189      0|===========================                                
-1035  12176      0|===========================                                
-1034  12350      0|============================                               
-1033  12423      0|============================                               
-1032  12731      0|============================                               
-1031  12783      0|=============================                              
-1030  12813      0|=============================                              
-1029  12977      0|=============================                              
-1028  12801      0|=============================                              
-1027  13132      0|=============================                              
-1026  13386      0|==============================                             
-1025  13549      0|==============================                             
-1024  13441      0|==============================                             
-1023  13766      0|===============================                            
-1022  13754      0|===============================                            
-1021  13651      0|==============================                             
-1020  13813      0|===============================                            
-1019  13786      0|===============================                            
-1018  13445      0|==============================                             
-1017  13828      0|===============================                            
-1016  13939      0|===============================                            
-1015  13884      0|===============================                            
-1014  13890      0|===============================                            
-1013  14327      0|================================                           
-1012  14056      0|===============================                            
-1011  14307      0|================================                           
-1010  14412      0|================================                           
-1009  14398      0|================================                           
-1008  14630      0|=================================                          
-1007  14715      0|=================================                          
-1006  15016      0|=================================                          
-1005  15154      0|==================================                         
-1004  15477      0|==================================                         
-1003  15690      0|===================================                        
-1002  15707      0|===================================                        
-1001  15697      0|===================================                        
-1000  16008      0|====================================                       
 -999  16263      0|====================================                       
 -998  16563      0|=====================================                      
 -997  16546      0|=====================================                      
 -996  16915      0|======================================                     
 -995  17001      0|======================================                     
 -994  16944      0|======================================                     
 -993  17186      0|======================================                     
 -992  17483      0|=======================================                    
 -991  17496      0|=======================================                    
 -990  17843      0|========================================                   
 -989  17684      0|=======================================                    
 -988  18083      0|========================================                   
 -987  18470      0|=========================================                  
 -986  18617      0|=========================================                  
 -985  18788      0|==========================================                 
 -984  19291      0|===========================================                
 -983  19221      0|===========================================                
 -982  19520      0|===========================================                
 -981  19967      0|============================================               
 -980  19755      0|============================================               
 -979  19646      1|*===========================================               
 -978  19734      1|*===========================================               
 -977  19539      1|*==========================================                
 -976  18973      1|*=========================================                 
 -975  18720      2|*=========================================                 
 -974  19013      2|*=========================================                 
 -973  18945      2|*=========================================                 
 -972  18951      3|*=========================================                 
 -971  19056      3|*=========================================                 
 -970  19135      4|*=========================================                 
 -969  19127      5|*=========================================                 
 -968  19300      6|*==========================================                
 -967  19254      7|*==========================================                
 -966  19661      8|*===========================================               
 -965  19558      9|*==========================================                
 -964  19830     11|*===========================================               
 -963  19638     13|*===========================================               
 -962  19579     15|*==========================================                
 -961  19743     17|*===========================================               
 -960  19711     20|*===========================================               
 -959  19748     22|*===========================================               
 -958  19775     26|*===========================================               
 -957  19801     29|*===========================================               
 -956  19748     33|*===========================================               
 -955  19585     38|*==========================================                
 -954  19893     43|*===========================================               
 -953  19608     49|*==========================================                
 -952  19479     55|*==========================================                
 -951  19642     62|*===========================================               
 -950  19554     70|*==========================================                
 -949  19826     79|*===========================================               
 -948  19805     89|*===========================================               
 -947  19917     99|*===========================================               
 -946  19905    111|*===========================================               
 -945  20168    124|*============================================              
 -944  20043    138|*===========================================               
 -943  20572    154|*=============================================             
 -942  20214    171|*============================================              
 -941  20522    189|*=============================================             
 -940  20095    210|*============================================              
 -939  20117    232|*============================================              
 -938  20290    256|*============================================              
 -937  20370    282|*============================================              
 -936  20359    311|*============================================              
 -935  20432    342|*============================================              
 -934  20317    375|*============================================              
 -933  20623    411|*=============================================             
 -932  20239    450|*============================================              
 -931  20600    492|=*============================================             
 -930  20751    537|=*============================================             
 -929  20835    586|=*============================================             
 -928  21239    638|=*=============================================            
 -927  20770    694|=*============================================             
 -926  20774    753|=*============================================             
 -925  20835    817|=*============================================             
 -924  20814    885|=*============================================             
 -923  20711    958|==*===========================================             
 -922  20641   1035|==*===========================================             
 -921  20769   1117|==*===========================================             
 -920  20661   1204|==*===========================================             
 -919  20873   1297|==*===========================================             
 -918  20799   1395|===*==========================================             
 -917  20511   1499|===*=========================================              
 -916  20748   1609|===*==========================================             
 -915  20662   1725|===*==========================================             
 -914  20653   1847|====*=========================================             
 -913  20692   1976|====*=========================================             
 -912  21003   2112|====*==========================================            
 -911  20793   2254|====*=========================================             
 -910  21006   2404|=====*=========================================            
 -909  20983   2561|=====*=========================================            
 -908  21204   2726|=====*=========================================            
 -907  21291   2899|======*========================================            
 -906  21163   3079|======*========================================            
 -905  21161   3267|=======*=======================================            
 -904  21207   3464|=======*=======================================            
 -903  21171   3669|========*======================================            
 -902  21448   3882|========*=======================================           
 -901  21534   4105|=========*======================================           
 -900  21537   4336|=========*======================================           
 -899  21639   4576|==========*=====================================           
 -898  21591   4825|==========*=====================================           
 -897  21533   5083|===========*====================================           
 -896  21266   5351|===========*===================================            
 -895  21352   5627|============*==================================            
 -894  21284   5914|============*==================================            
 -893  21512   6209|=============*==================================           
 -892  21196   6514|==============*================================            
 -891  21160   6829|==============*================================            
 -890  21349   7153|===============*===============================            
 -889  21260   7487|================*==============================            
 -888  21298   7830|=================*=============================            
 -887  21249   8183|=================*=============================            
 -886  21540   8546|==================*=============================           
 -885  21992   8917|===================*=============================          
 -884  22152   9299|====================*============================          
 -883  22395   9689|=====================*============================         
 -882  22541  10089|======================*===========================         
 -881  22830  10498|=======================*===========================        
 -880  22999  10916|=======================*===========================        
 -879  23352  11343|========================*===========================       
 -878  23407  11778|=========================*==========================       
 -877  23617  12223|==========================*=========================       
 -876  23771  12675|===========================*=========================      
 -875  23778  13136|============================*========================      
 -874  23630  13605|=============================*======================       
 -873  23850  14082|==============================*======================      
 -872  23756  14566|===============================*=====================      
 -871  23831  15058|=================================*===================      
 -870  23687  15557|==================================*=================       
 -869  23380  16063|===================================*================       
 -868  23181  16575|====================================*==============        
 -867  23448  17094|=====================================*==============       
 -866  23516  17620|======================================*=============       
 -865  23220  18150|=======================================*===========        
 -864  23250  18687|========================================*==========        
 -863  23563  19228|==========================================*=========       
 -862  23243  19775|===========================================*=======        
 -861  23566  20326|============================================*=======       
 -860  23622  20881|=============================================*======       
 -859  23745  21441|===============================================*=====      
 -858  23722  22004|================================================*====      
 -857  23828  22570|=================================================*===      
 -856  23745  23139|==================================================*==      
 -855  23831  23710|===================================================*=      
 -854  23918  24284|=====================================================*     
 -853  23773  24860|===================================================== *    
 -852  23864  25437|=====================================================  *   
 -851  23277  26015|====================================================     * 
 -850  23664  26594|====================================================      *
 -849  23178  27173|===================================================       *
 -848  23553  27752|====================================================      *
 -847  23108  28331|===================================================       *
 -846  23211  28909|===================================================       *
 -845  23192  29486|===================================================       *
 -844  23371  30062|====================================================      *
 -843  23182  30636|===================================================       *
 -842  23197  31208|===================================================       *
 -841  23434  31777|====================================================      *
 -840  23126  32343|===================================================       *
 -839  23225  32907|===================================================       *
 -838  23211  33467|===================================================       *
 -837  23345  34023|====================================================      *
 -836  22909  34574|===================================================       *
 -835  23357  35122|====================================================      *
 -834  23297  35664|====================================================      *
 -833  23209  36201|===================================================       *
 -832  23678  36733|====================================================      *
 -831  23731  37260|=====================================================     *
 -830  23405  37780|====================================================      *
 -829  23850  38294|=====================================================     *
 -828  23629  38801|====================================================      *
 -827  23804  39302|=====================================================     *
 -826  23950  39796|=====================================================     *
 -825  24232  40282|======================================================    *
 -824  24005  40760|=====================================================     *
 -823  24410  41231|======================================================    *
 -822  24205  41694|======================================================    *
 -821  24010  42149|=====================================================     *
 -820  24084  42595|=====================================================     *
 -819  24210  43033|======================================================    *
 -818  24208  43462|======================================================    *
 -817  24322  43882|======================================================    *
 -816  24427  44292|======================================================    *
 -815  24165  44694|=====================================================     *
 -814  24310  45086|======================================================    *
 -813  24129  45468|=====================================================     *
 -812  24291  45841|======================================================    *
 -811  24347  46204|======================================================    *
 -810  23883  46557|=====================================================     *
 -809  24413  46900|======================================================    *
 -808  24360  47233|======================================================    *
 -807  24193  47555|======================================================    *
 -806  24436  47867|======================================================    *
 -805  24407  48169|======================================================    *
 -804  24517  48461|======================================================    *
 -803  24283  48742|======================================================    *
 -802  24830  49012|=======================================================   *
 -801  24322  49272|======================================================    *
 -800  24425  49521|======================================================    *
 -799  24612  49760|======================================================    *
 -798  24461  49988|======================================================    *
 -797  24340  50206|======================================================    *
 -796  24623  50413|======================================================    *
 -795  24746  50609|=======================================================   *
 -794  24903  50795|=======================================================   *
 -793  24893  50970|=======================================================   *
 -792  24511  51135|======================================================    *
 -791  24830  51289|=======================================================   *
 -790  24833  51433|=======================================================   *
 -789  25122  51566|========================================================  *
 -788  24954  51690|=======================================================   *
 -787  25323  51803|========================================================  *
 -786  25216  51905|========================================================  *
 -785  24986  51998|=======================================================   *
 -784  25193  52081|========================================================  *
 -783  25330  52153|========================================================  *
 -782  25653  52216|========================================================= *
 -781  25558  52270|========================================================= *
 -780  25759  52313|========================================================= *
 -779  25693  52347|========================================================= *
 -778  25934  52371|========================================================= *
 -777  26059  52387|==========================================================*
 -776  26259  52393|==========================================================*
 -775  26025  52390|==========================================================*
 -774  26005  52377|==========================================================*
 -773  26319  52357|==========================================================*
 -772  26555  52327|==========================================================*
 -771  26255  52289|==========================================================*
 -770  26350  52242|==========================================================*
 -769  26093  52187|==========================================================*
 -768  26248  52123|==========================================================*
 -767  26414  52052|==========================================================*
 -766  26441  51973|==========================================================*
 -765  26840  51886|==========================================================*
 -764  26678  51791|==========================================================*
 -763  26550  51689|==========================================================*
 -762  26903  51580|==========================================================*
 -761  26797  51463|==========================================================*
 -760  26849  51339|==========================================================*
 -759  26730  51208|==========================================================*
 -758  26705  51071|==========================================================*
 -757  26547  50927|==========================================================*
 -756  26494  50776|==========================================================*
 -755  26573  50620|==========================================================*
 -754  26792  50457|==========================================================*
 -753  26356  50288|==========================================================*
 -752  26245  50113|==========================================================*
 -751  26006  49932|==========================================================*
 -750  25880  49746|========================================================= *
 -749  25669  49555|========================================================= *
 -748  25512  49358|========================================================  *
 -747  25675  49156|========================================================= *
 -746  25794  48949|========================================================= *
 -745  25741  48737|========================================================= *
 -744  25699  48521|========================================================= *
 -743  25854  48300|========================================================= *
 -742  25373  48075|========================================================  *
 -741  25376  47845|========================================================  *
 -740  25596  47611|========================================================= *
 -739  25334  47373|========================================================  *
 -738  25542  47132|========================================================= *
 -737  24965  46887|=======================================================   *
 -736  25333  46638|========================================================  *
 -735  25238  46385|========================================================  *
 -734  24977  46130|=======================================================   *
 -733  25443  45871|========================================================  *
 -732  25207  45609|========================================================  *
 -731  25284  45345|========================================================  *
 -730  25000  45077|=======================================================   *
 -729  25073  44807|=======================================================   *
 -728  25202  44534|========================================================  *
 -727  24844  44259|=======================================================   *
 -726  25024  43982|=======================================================   *
 -725  24997  43702|=======================================================   *
 -724  25036  43420|=======================================================   *
 -723  24778  43136|=======================================================   *
 -722  24960  42851|=======================================================   *
 -721  24949  42564|=======================================================   *
 -720  24830  42275|=======================================================   *
 -719  24549  41984|======================================================    *
 -718  24438  41692|======================================================    *
 -717  24840  41399|=======================================================   *
 -716  24498  41105|======================================================    *
 -715  24456  40809|======================================================    *
 -714  24392  40513|======================================================    *
 -713  24426  40215|======================================================    *
 -712  24311  39917|======================================================    *
 -711  24521  39618|======================================================    *
 -710  24020  39318|=====================================================     *
 -709  24096  39018|=====================================================     *
 -708  23806  38717|=====================================================     *
 -707  23705  38416|====================================================      *
 -706  23310  38114|====================================================      *
 -705  23284  37812|====================================================      *
 -704  23216  37510|===================================================       *
 -703  23181  37208|===================================================       *
 -702  22887  36906|===================================================       *
 -701  22482  36604|==================================================        *
 -700  22288  36302|=================================================         *
 -699  22382  36001|==================================================        *
 -698  22235  35699|=================================================         *
 -697  21944  35398|=================================================         *
 -696  21762  35097|================================================          *
 -695  21635  34797|================================================          *
 -694  21319  34497|===============================================           *
 -693  21733  34198|================================================          *
 -692  21734  33900|================================================          *
 -691  21608  33602|================================================          *
 -690  21394  33304|===============================================           *
 -689  21411  33008|===============================================           *
 -688  21601  32712|================================================          *
 -687  21159  32418|===============================================           *
 -686  21387  32124|===============================================           *
 -685  21626  31831|================================================          *
 -684  21612  31539|================================================          *
 -683  21419  31249|===============================================           *
 -682  21400  30959|===============================================           *
 -681  21358  30671|===============================================           *
 -680  21487  30383|================================================          *
 -679  21181  30097|===============================================           *
 -678  21307  29812|===============================================           *
 -677  21042  29529|===============================================           *
 -676  21340  29246|===============================================           *
 -675  20945  28966|==============================================            *
 -674  20905  28686|==============================================            *
 -673  20684  28408|==============================================            *
 -672  20870  28131|==============================================            *
 -671  20607  27856|==============================================            *
 -670  20540  27582|==============================================            *
 -669  20420  27310|=============================================             *
 -668  20563  27040|==============================================            *
 -667  20530  26770|==============================================            *
 -666  20449  26503|=============================================             *
 -665  20588  26237|==============================================           * 
 -664  20077  25973|=============================================           *  
 -663  20252  25710|=============================================           *  
 -662  20419  25449|=============================================          *   
 -661  20167  25190|=============================================          *   
 -660  20272  24932|=============================================         *    
 -659  20283  24676|=============================================         *    
 -658  20322  24422|=============================================        *     
 -657  20222  24169|=============================================        *     
 -656  20036  23919|============================================        *      
 -655  19892  23670|============================================       *       
 -654  19695  23423|============================================       *       
 -653  19833  23177|============================================      *        
 -652  19570  22933|===========================================       *        
 -651  19752  22692|============================================     *         
 -650  19609  22451|============================================     *         
 -649  19472  22213|===========================================     *          
 -648  19279  21977|===========================================     *          
 -647  19369  21742|===========================================    *           
 -646  19432  21509|===========================================    *           
 -645  19184  21278|===========================================   *            
 -644  19165  21049|===========================================   *            
 -643  19084  20822|==========================================   *             
 -642  18917  20596|==========================================   *             
 -641  18798  20373|==========================================  *              
 -640  18911  20151|==========================================  *              
 -639  18756  19931|========================================== *               
 -638  18587  19713|=========================================  *               
 -637  18719  19496|==========================================*                
 -636  18320  19282|========================================= *                
 -635  18502  19069|=========================================*                 
 -634  18722  18858|=========================================*                 
 -633  18327  18649|========================================*                  
 -632  18118  18442|========================================*                  
 -631  18141  18237|=======================================*                   
 -630  17909  18034|=======================================*                   
 -629  18078  17832|=======================================*                   
 -628  18001  17632|======================================*=                   
 -627  17857  17434|======================================*=                   
 -626  17974  17238|=====================================*==                   
 -625  17900  17043|=====================================*==                   
 -624  17503  16851|====================================*==                    
 -623  17393  16660|====================================*==                    
 -622  17223  16471|====================================*=                     
 -621  16953  16283|===================================*==                     
 -620  17220  16098|===================================*==                     
 -619  16895  15914|==================================*===                     
 -618  16881  15732|==================================*===                     
 -617  16953  15552|==================================*===                     
 -616  16346  15373|=================================*==                       
 -615  16530  15196|=================================*===                      
 -614  16647  15021|================================*====                      
 -613  16315  14848|================================*===                       
 -612  16525  14676|================================*====                      
 -611  16099  14506|===============================*====                       
 -610  16179  14338|===============================*====                       
 -609  16332  14171|===============================*====                       
 -608  16427  14006|==============================*======                      
 -607  16095  13843|==============================*=====                       
 -606  16208  13681|==============================*=====                       
 -605  16143  13521|=============================*======                       
 -604  16091  13363|=============================*======                       
 -603  15786  13206|============================*======                        
 -602  15678  13051|============================*======                        
 -601  15517  12897|============================*======                        
 -600  15675  12745|===========================*=======                        
 -599  15580  12595|===========================*=======                        
 -598  15634  12446|===========================*=======                        
 -597  15572  12298|==========================*========                        
 -596  15520  12153|==========================*========                        
 -595  15461  12008|==========================*=======                         
 -594  15296  11866|==========================*=======                         
 -593  15151  11725|=========================*========                         
 -592  14896  11585|=========================*=======                          
 -591  14887  11447|=========================*=======                          
 -590  14826  11310|========================*========                          
 -589  14567  11175|========================*=======                           
 -588  14454  11041|========================*=======                           
 -587  14442  10908|=======================*========                           
 -586  14396  10778|=======================*========                           
 -585  14590  10648|=======================*========                           
 -584  14503  10520|=======================*========                           
 -583  14406  10393|======================*=========                           
 -582  14391  10268|======================*=========                           
 -581  14422  10144|======================*=========                           
 -580  14153  10021|=====================*==========                           
 -579  14073   9900|=====================*=========                            
 -578  14063   9780|=====================*=========                            
 -577  13648   9662|=====================*========                             
 -576  13911   9544|====================*==========                            
 -575  13871   9428|====================*==========                            
 -574  13549   9314|====================*=========                             
 -573  13622   9200|====================*=========                             
 -572  13171   9088|===================*=========                              
 -571  13051   8977|===================*=========                              
 -570  12886   8868|===================*=========                              
 -569  12831   8759|===================*=========                              
 -568  12656   8652|==================*=========                               
 -567  12882   8546|==================*==========                              
 -566  12515   8442|==================*=========                               
 -565  11987   8338|==================*========                                
 -564  12144   8236|==================*========                                
 -563  11764   8135|=================*========                                 
 -562  11520   8035|=================*========                                 
 -561  11281   7936|=================*=======                                  
 -560  11016   7838|=================*=======                                  
 -559  10928   7741|================*=======                                   
 -558  10403   7646|================*======                                    
 -557  10335   7552|================*======                                    
 -556  10186   7458|================*======                                    
 -555   9922   7366|================*=====                                     
 -554   9497   7275|===============*=====                                      
 -553   9388   7185|===============*=====                                      
 -552   9259   7096|===============*=====                                      
 -551   8888   7008|===============*====                                       
 -550   8437   6921|===============*===                                        
 -549   8270   6835|==============*====                                        
 -548   8134   6750|==============*===                                         
 -547   8007   6666|==============*===                                         
 -546   7633   6583|==============*==                                          
 -545   7429   6501|==============*==                                          
 -544   7254   6420|==============*=                                           
 -543   7086   6340|=============*==                                           
 -542   6842   6261|=============*==                                           
 -541   6712   6183|=============*=                                            
 -540   6600   6106|=============*=                                            
 -539   6284   6029|=============*                                             
 -538   6073   5954|=============*                                             
 -537   5774   5879|============*                                              
 -536   5576   5806|============*                                              
 -535   5367   5733|============*                                              
 -534   5216   5661|============*                                              
 -533   5214   5590|============*                                              
 -532   4842   5520|=========== *                                              
 -531   4791   5451|===========*                                               
 -530   4747   5382|===========*                                               
 -529   4450   5314|========== *                                               
 -528   4334   5248|========== *                                               
 -527   4172   5182|========== *                                               
 -526   3998   5116|=========  *                                               
 -525   4062   5052|=========  *                                               
 -524   3910   4988|========= *                                                
 -523   3629   4925|========  *                                                
 -522   3670   4863|========= *                                                
 -521   3447   4802|========  *                                                
 -520   3214   4741|========  *                                                
 -519   3119   4681|=======   *                                                
 -518   3108   4622|=======   *                                                
 -517   2912   4564|=======   *                                                
 -516   2896   4506|=======  *                                                 
 -515   2888   4449|=======  *                                                 
 -514   2665   4393|======   *                                                 
 -513   2439   4337|======   *                                                 
 -512   2502   4282|======   *                                                 
 -511   2376   4228|======   *                                                 
 -510   2268   4174|=====    *                                                 
 -509   2135   4121|=====    *                                                 
 -508   2150   4069|=====   *                                                  
 -507   2065   4017|=====   *                                                  
 -506   1919   3966|=====   *                                                  
 -505   1814   3916|====    *                                                  
 -504   1761   3866|====    *                                                  
 -503   1798   3817|====    *                                                  
 -502   1672   3768|====    *                                                  
 -501   1650   3720|====    *                                                  
 -500   1586   3673|====    *                                                  
 -499   1460   3626|====   *                                                   
 -498   1427   3580|====   *                                                   
 -497   1391   3534|====   *                                                   
 -496   1264   3489|===    *                                                   
 -495   1200   3445|===    *                                                   
 -494   1234   3401|===    *                                                   
 -493   1150   3357|===    *                                                   
 -492   1134   3314|===    *                                                   
 -491   1086   3272|===    *                                                   
 -490   1070   3230|===    *                                                   
 -489   1007   3189|===   *                                                    
 -488   1019   3148|===   *                                                    
 -487    949   3108|===   *                                                    
 -486    930   3068|===   *                                                    
 -485    911   3029|==    *                                                    
 -484    886   2990|==    *                                                    
 -483    813   2952|==    *                                                    
 -482    783   2914|==    *                                                    
 -481    777   2877|==    *                                                    
 -480    764   2840|==    *                                                    
 -479    655   2803|==    *                                                    
 -478    688   2768|==    *                                                    
 -477    674   2732|==   *                                                     
 -476    693   2697|==   *                                                     
 -475    627   2662|==   *                                                     
 -474    653   2628|==   *                                                     
 -473    588   2594|==   *                                                     
 -472    582   2561|==   *                                                     
 -471    583   2528|==   *                                                     
 -470    607   2496|==   *                                                     
 -469    529   2464|==   *                                                     
 -468    503   2432|==   *                                                     
 -467    498   2401|==   *                                                     
 -466    509   2370|==   *                                                     
 -465    543   2339|==   *                                                     
 -464    457   2309|==   *                                                     
 -463    476   2280|==  *                                                      
 -462    474   2250|==  *                                                      
 -461    459   2221|==  *                                                      
 -460    389   2193|=   *                                                      
 -459    397   2164|=   *                                                      
 -458    367   2137|=   *                                                      
 -457    408   2109|=   *                                                      
 -456    397   2082|=   *                                                      
 -455    410   2055|=   *                                                      
 -454    373   2029|=   *                                                      
 -453    357   2002|=   *                                                      
 -452    388   1977|=   *                                                      
 -451    379   1951|=   *                                                      
 -450    336   1926|=   *                                                      
 -449    343   1901|=   *                                                      
 -448    281   1877|=   *                                                      
 -447    307   1852|=   *                                                      
 -446    318   1828|=   *                                                      
 -445    295   1805|=  *                                                       
 -444    295   1781|=  *                                                       
 -443    276   1758|=  *                                                       
 -442    235   1736|=  *                                                       
 -441    271   1713|=  *                                                       
 -440    278   1691|=  *                                                       
 -439    233   1669|=  *                                                       
 -438    251   1648|=  *                                                       
 -437    263   1626|=  *                                                       
 -436    269   1605|=  *                                                       
 -435    219   1585|=  *                                                       
 -434    225   1564|=  *                                                       
 -433    222   1544|=  *                                                       
 -432    212   1524|=  *                                                       
 -431    213   1504|=  *                                                       
 -430    202   1485|=  *                                                       
 -429    208   1465|=  *                                                       
 -428    193   1446|=  *                                                       
 -427    190   1428|=  *                                                       
 -426    170   1409|=  *                                                       
 -425    153   1391|=  *                                                       
 -424    173   1373|=  *                                                       
 -423    178   1355|= *                                                        
 -422    144   1338|= *                                                        
 -421    155   1320|= *                                                        
 -420    152   1303|= *                                                        
 -419    145   1286|= *                                                        
 -418    147   1270|= *                                                        
 -417    100   1253|= *                                                        
 -416    121   1237|= *                                                        
 -415    162   1221|= *                                                        
 -414    106   1205|= *                                                        
 -413    102   1189|= *                                                        
 -412    111   1174|= *                                                        
 -411    105   1159|= *                                                        
 -410     94   1144|= *                                                        
 -409     85   1129|= *                                                        
 -408     96   1114|= *                                                        
 -407     84   1100|= *                                                        
 -406     99   1085|= *                                                        
 -405     87   1071|= *                                                        
 -404     67   1057|= *                                                        
 -403     50   1044|= *                                                        
 -402     67   1030|= *                                                        
 -401     64   1017|= *                                                        
 -400     58   1004|= *                                                        
 -399     41    991|= *                                                        
 -398     46    978|= *                                                        
 -397     42    965|= *                                                        
 -396     45    952|= *                                                        
 -395     55    940|= *                                                        
 -394     42    928|= *                                                        
 -393     30    916|= *                                                        
 -392     34    904|=*                                                         
 -391     49    892|=*                                                         
 -390     30    880|=*                                                         
 -389     29    869|=*                                                         
 -388     23    858|=*                                                         
 -387     26    847|=*                                                         
 -386     28    836|=*                                                         
 -385     30    825|=*                                                         
 -384     18    814|=*                                                         
 -383     14    803|=*                                                         
 -382     15    793|=*                                                         
 -381     11    783|=*                                                         
 -380     48    772|=*                                                         
 -379     17    762|=*                                                         
 -378     37    752|=*                                                         
 -377     18    743|=*                                                         
 -376     12    733|=*                                                         
 -375      8    723|=*                                                         
 -374     12    714|=*                                                         
 -373      8    705|=*                                                         
 -372     15    696|=*                                                         
 -371      4    686|=*                                                         
 -370      5    678|=*                                                         
 -369      9    669|=*                                                         
 -368      7    660|=*                                                         
 -367     11    651|=*                                                         
 -366     26    643|=*                                                         
 -365     12    635|=*                                                         
 -364      4    626|=*                                                         
 -363      5    618|=*                                                         
 -362      3    610|=*                                                         
 -361      2    602|=*                                                         
 -360      5    594|=*                                                         
 -359      7    587|=*                                                         
 -358      2    579|=*                                                         
 -357      1    571|=*                                                         
 -356      3    564|=*                                                         
 -355      0    557| *                                                         
 -354      4    549|=*                                                         
 -353      2    542|=*                                                         
 -352      0    535| *                                                         
 -351      7    528|=*                                                         
 -350      0    521| *                                                         
 -349      1    514|=*                                                         
 -348      3    508|=*                                                         
 -347      0    501| *                                                         
 -346      0    495| *                                                         
 -345      1    488|=*                                                         
 -344      0    482| *                                                         
 -343      3    475|=*                                                         
 -342      1    469|=*                                                         
 -341      1    463|=*                                                         
 -340      1    457|=*                                                         
 -339      0    451|*                                                          
 -338      1    445|*                                                          
 -337      1    439|*                                                          
 -336      0    434|*                                                          
 -335      0    428|*                                                          
 -334      1    422|*                                                          
 -333      0    417|*                                                          
 -332      1    411|*                                                          
 -331      1    406|*                                                          
>-330    178      -|=                                                          


% Statistical details of theoretical EVD fit:
              mu =  -775.3455
          lambda =     0.0132
chi-sq statistic = 544518464.0000
  P(chi-square)  =          0

Total sequences searched: 10818955

Whole sequence top hits:
tophits_s report:
     Total hits:           163
     Satisfying E cutoff:  146
     Total memory:         41K

Domain top hits:
tophits_s report:
     Total hits:           163
     Satisfying E cutoff:  163
     Total memory:         536K
