hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                   /home/wongwc/DOMERR/bin/phase6/HMMmodels/globalmode-hmmpfam/PF07217.3_Heterokaryon_incompatibility_protein_Het-C.hmmmodel [PF07217.3_Heterokaryon_incompatibility_protein_Het-C]
Sequence database:          /home/wongwc/DOMERR/data/nr-05-04-2010.fasta
per-sequence score cutoff:  [none]
per-domain score cutoff:    [none]
per-sequence Eval cutoff:   <= 10        
per-domain Eval cutoff:     [none]
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Query HMM:   PF07217.3_Heterokaryon_incompatibility_protein_Het-C
Accession:   [none]
Description: [none]
  [HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence                            Description         Score    E-value  N 
--------                            -----------         -----    ------- ---
gi|18376334|emb|CAD21080.1|         glycine rich prot  1705.0          0   1
gi|1261823|gb|AAB48349.1|           glycine rich prot  1669.6          0   1
gi|171690006|ref|XP_001909935.1|    unnamed protein p  1638.5          0   1
gi|14029167|gb|AAK51159.1|          Bc-hch [Botryotin  1632.6          0   1
gi|154322635|ref|XP_001560632.1|    hypothetical prot  1631.2          0   1
gi|6425089|gb|AAF08294.1|AF195874_1 heterokaryon inco  1600.4          0   1
gi|156064873|ref|XP_001598358.1|    hypothetical prot  1593.5          0   1
gi|289614135|emb|CBI61504.1|        putative heteroka  1537.2          0   1
gi|6425091|gb|AAF08295.1|AF196305_1 heterokaryon inco  1531.3          0   1
gi|164427442|ref|XP_955880.2|       hypothetical prot  1500.3          0   1
gi|116200111|ref|XP_001225867.1|    hypothetical prot  1427.6          0   1
gi|256732973|gb|EEU46321.1|         predicted protein  1358.1          0   1
gi|67772310|gb|AAY79377.1|          hch [Fusarium pro  1349.6          0   1
gi|46121569|ref|XP_385339.1|        hypothetical prot  1336.1          0   1
gi|145607013|ref|XP_361445.2|       hypothetical prot  1140.3          0   1
gi|159129974|gb|EDP55088.1|         HET-C domain prot  1083.2          0   1
gi|119482037|ref|XP_001261047.1|    HET-C domain prot  1081.6          0   1
gi|71002476|ref|XP_755919.1|        HET-C domain prot  1079.1          0   1
gi|121716642|ref|XP_001275868.1|    HET-C domain prot  1075.0          0   1
gi|258573359|ref|XP_002540861.1|    conserved hypothe  1052.2          0   1
gi|145251257|ref|XP_001397142.1|    hypothetical prot  1046.1          0   1
gi|67523423|ref|XP_659771.1|        hypothetical prot  1041.8          0   1
gi|115388269|ref|XP_001211640.1|    hypothetical prot  1036.4          0   1
gi|240106324|gb|EER24517.1|         Heterokaryon inco  1034.6          0   1
gi|119191852|ref|XP_001246532.1|    hypothetical prot  1032.2          0   1
gi|169762762|ref|XP_001727281.1|    hypothetical prot  1011.8   2.6e-301   1
gi|238488583|ref|XP_002375529.1|    HET-C domain prot  1011.8   2.6e-301   1
gi|255953065|ref|XP_002567285.1|    Pc21g02200 [Penic  1010.8   5.5e-301   1
gi|238845486|gb|EEQ35148.1|         HET-C domain-cont   994.8   3.6e-296   1
gi|291178161|gb|EFE33952.1|         hypothetical prot   983.5   8.7e-293   1
gi|291187190|gb|EFE42589.1|         hypothetical prot   972.8   1.4e-289   1
gi|212535568|ref|XP_002147940.1|    HET-C domain prot   965.7   2.1e-287   1
gi|189189364|ref|XP_001931021.1|    HET domain contai   963.0   1.4e-286   1
gi|242793481|ref|XP_002482170.1|    HET-C domain prot   954.2   5.7e-284   1
gi|169608293|ref|XP_001797566.1|    hypothetical prot   954.1   6.2e-284   1
gi|226286434|gb|EEH42000.1|         HET-C domain-cont   906.3   1.6e-269   1
gi|261204825|ref|XP_002629626.1|    HET-C domain-cont   864.9   4.6e-257   1
gi|239614043|gb|EEQ91030.1|         HET-C domain-cont   864.9   4.6e-257   1
gi|226291888|gb|EEH47316.1|         HET-C domain-cont   832.1   3.3e-247   1
gi|154286346|ref|XP_001543968.1|    hypothetical prot   791.0   7.8e-235   1
gi|240274951|gb|EER38466.1|         HET-C protein [Aj   756.8   1.6e-224   1
gi|225558518|gb|EEH06802.1|         HET-C domain-cont   752.8   2.5e-223   1
gi|225680092|gb|EEH18376.1|         HET-C domain prot   669.9   2.3e-198   1
gi|115385404|ref|XP_001209249.1|    hypothetical prot   652.2   4.8e-193   1
gi|169621851|ref|XP_001804335.1|    hypothetical prot   643.3   2.4e-190   1
gi|189196973|ref|XP_001934824.1|    NIMA-interacting    637.8     1e-188   1
gi|291181387|gb|EFE37171.1|         hypothetical prot   628.7   5.7e-186   1
gi|67904160|ref|XP_682336.1|        hypothetical prot   628.0     9e-186   1
gi|291186721|gb|EFE42141.1|         hypothetical prot   627.4   1.4e-185   1
gi|119489357|ref|XP_001262889.1|    NIMA-interacting    616.3   3.1e-182   1
gi|70982294|ref|XP_746675.1|        NIMA-interacting    614.1   1.4e-181   1
gi|255954861|ref|XP_002568183.1|    Pc21g11520 [Penic   606.3   3.2e-179   1
gi|238843618|gb|EEQ33280.1|         NIMA-interacting    602.8   3.5e-178   1
gi|240107631|gb|EER25810.1|         Heterokaryon inco   602.2   5.3e-178   1
gi|119177578|ref|XP_001240545.1|    hypothetical prot   602.2   5.6e-178   1
gi|58262802|ref|XP_568811.1|        heterokaryon inco   597.5   1.4e-176   1
gi|256735483|gb|EEU48829.1|         predicted protein   596.9   2.2e-176   1
gi|46107690|ref|XP_380904.1|        hypothetical prot   591.1   1.2e-174   1
gi|50546531|ref|XP_500735.1|        YALI0B10802p [Yar   587.3   1.7e-173   1
gi|240281027|gb|EER44530.1|         NIMA interacting    585.5   5.7e-173   1
gi|225562540|gb|EEH10819.1|         NIMA-interacting    583.0   3.3e-172   1
gi|226292756|gb|EEH48176.1|         HET-C protein [Pa   582.8   3.9e-172   1
gi|261205192|ref|XP_002627333.1|    NIMA-interacting    575.0   8.3e-170   1
gi|239611449|gb|EEQ88436.1|         NIMA-interacting    575.0   8.3e-170   1
gi|225680602|gb|EEH18886.1|         NIMA-interacting    570.5   1.8e-168   1
gi|39951367|ref|XP_363400.1|        hypothetical prot   563.8     2e-166   1
gi|258564130|ref|XP_002582810.1|    hypothetical prot   563.5   2.4e-166   1
gi|85116042|ref|XP_964984.1|        hypothetical prot   557.4   1.7e-164   1
gi|121709055|ref|XP_001272292.1|    NIMA-interacting    548.8   6.5e-162   1
gi|289617909|emb|CBI55486.1|        unnamed protein p   543.8   2.1e-160   1
gi|71014539|ref|XP_758725.1|        hypothetical prot   540.0   2.9e-159   1
gi|171687657|ref|XP_001908769.1|    unnamed protein p   538.3   9.4e-159   1
gi|156053868|ref|XP_001592860.1|    hypothetical prot   538.3   9.6e-159   1
gi|169851344|ref|XP_001832362.1|    hypothetical prot   537.0   2.4e-158   1
gi|242206537|ref|XP_002469124.1|    predicted protein   521.3   1.2e-153   1
gi|39960084|ref|XP_364543.1|        hypothetical prot   509.4   4.7e-150   1
gi|154279436|ref|XP_001540531.1|    conserved hypothe   500.9   1.6e-147   1
gi|50557358|ref|XP_506087.1|        YALI0F31251p [Yar   498.6   8.5e-147   1
gi|170099658|ref|XP_001881047.1|    predicted protein   476.3   4.2e-140   1
gi|169845161|ref|XP_001829300.1|    hypothetical prot   473.0   4.3e-139   1
gi|169782124|ref|XP_001825525.1|    hypothetical prot   458.8   8.2e-135   1
gi|116180482|ref|XP_001220090.1|    hypothetical prot   456.8   3.1e-134   1
gi|238498984|ref|XP_002380727.1|    cell cycle contro   423.7     3e-124   1
gi|46112807|ref|XP_383081.1|        hypothetical prot   314.4    2.3e-91   1
gi|256721170|gb|EEU34581.1|         predicted protein   309.6    6.3e-90   1
gi|226283048|gb|EEH38614.1|         conserved hypothe   259.5    7.8e-75   1
gi|261356832|gb|EEY19260.1|         Het-C protein [Ve   166.3    8.7e-47   1
gi|242211740|ref|XP_002471707.1|    predicted protein     5.3       0.76   1

Parsed for domains:
Sequence                            Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------                            ------- ----- -----    ----- -----      -----  -------
gi|18376334|emb|CAD21080.1|           1/1       1   651 [.     1   673 []  1705.0        0
gi|1261823|gb|AAB48349.1|             1/1       1   640 [.     1   673 []  1669.6        0
gi|171690006|ref|XP_001909935.1|      1/1       1   620 [.     1   673 []  1638.5        0
gi|14029167|gb|AAK51159.1|            1/1       1   627 [.     1   673 []  1632.6        0
gi|154322635|ref|XP_001560632.1|      1/1       1   627 [.     1   673 []  1631.2        0
gi|6425089|gb|AAF08294.1|AF195874_1   1/1       1   650 [.     1   673 []  1600.4        0
gi|156064873|ref|XP_001598358.1|      1/1       1   626 [.     1   673 []  1593.5        0
gi|289614135|emb|CBI61504.1|          1/1       1   633 [.     1   673 []  1537.2        0
gi|6425091|gb|AAF08295.1|AF196305_1   1/1       1   638 [.     1   673 []  1531.3        0
gi|164427442|ref|XP_955880.2|         1/1       1   612 [.     1   673 []  1500.3        0
gi|116200111|ref|XP_001225867.1|      1/1       1   623 [.     1   673 []  1427.6        0
gi|256732973|gb|EEU46321.1|           1/1       1   635 [.     1   673 []  1358.1        0
gi|67772310|gb|AAY79377.1|            1/1       1   636 [.     1   673 []  1349.6        0
gi|46121569|ref|XP_385339.1|          1/1       1   635 [.     1   673 []  1336.1        0
gi|145607013|ref|XP_361445.2|         1/1       1   579 [.     1   673 []  1140.3        0
gi|159129974|gb|EDP55088.1|           1/1       1   639 [.     1   673 []  1083.2        0
gi|119482037|ref|XP_001261047.1|      1/1       1   660 [.     1   673 []  1081.6        0
gi|71002476|ref|XP_755919.1|          1/1       1   639 [.     1   673 []  1079.1        0
gi|121716642|ref|XP_001275868.1|      1/1       1   649 [.     1   673 []  1075.0        0
gi|258573359|ref|XP_002540861.1|      1/1       1   635 [.     1   673 []  1052.2        0
gi|145251257|ref|XP_001397142.1|      1/1       1   606 [.     1   673 []  1046.1        0
gi|67523423|ref|XP_659771.1|          1/1       1   642 [.     1   673 []  1041.8        0
gi|115388269|ref|XP_001211640.1|      1/1       1   631 [.     1   673 []  1036.4        0
gi|240106324|gb|EER24517.1|           1/1       1   626 [.     1   673 []  1034.6        0
gi|119191852|ref|XP_001246532.1|      1/1       1   626 [.     1   673 []  1032.2        0
gi|169762762|ref|XP_001727281.1|      1/1       1   634 [.     1   673 []  1011.8 2.6e-301
gi|238488583|ref|XP_002375529.1|      1/1       1   634 [.     1   673 []  1011.8 2.6e-301
gi|255953065|ref|XP_002567285.1|      1/1       1   627 [.     1   673 []  1010.8 5.5e-301
gi|238845486|gb|EEQ35148.1|           1/1       1   623 [.     1   673 []   994.8 3.6e-296
gi|291178161|gb|EFE33952.1|           1/1       1   634 [.     1   673 []   983.5 8.7e-293
gi|291187190|gb|EFE42589.1|           1/1       1   624 [.     1   673 []   972.8 1.4e-289
gi|212535568|ref|XP_002147940.1|      1/1       5   663 ..     1   673 []   965.7 2.1e-287
gi|189189364|ref|XP_001931021.1|      1/1       1   613 [.     1   673 []   963.0 1.4e-286
gi|242793481|ref|XP_002482170.1|      1/1       1   669 [.     1   673 []   954.2 5.7e-284
gi|169608293|ref|XP_001797566.1|      1/1       1   625 [.     1   673 []   954.1 6.2e-284
gi|226286434|gb|EEH42000.1|           1/1     165   778 ..     1   673 []   906.3 1.6e-269
gi|261204825|ref|XP_002629626.1|      1/1       1   607 [.     1   673 []   864.9 4.6e-257
gi|239614043|gb|EEQ91030.1|           1/1       1   607 [.     1   673 []   864.9 4.6e-257
gi|226291888|gb|EEH47316.1|           1/1       1   594 [.     1   673 []   832.1 3.3e-247
gi|154286346|ref|XP_001543968.1|      1/1       1   612 [.     1   673 []   791.0 7.8e-235
gi|240274951|gb|EER38466.1|           1/1       1   570 [.     1   673 []   756.8 1.6e-224
gi|225558518|gb|EEH06802.1|           1/1       1   570 [.     1   673 []   752.8 2.5e-223
gi|225680092|gb|EEH18376.1|           1/1       1   504 [.     1   673 []   669.9 2.3e-198
gi|115385404|ref|XP_001209249.1|      1/1       1   607 [.     1   673 []   652.2 4.8e-193
gi|169621851|ref|XP_001804335.1|      1/1       1   600 [.     1   673 []   643.3 2.4e-190
gi|189196973|ref|XP_001934824.1|      1/1       1   602 [.     1   673 []   637.8   1e-188
gi|291181387|gb|EFE37171.1|           1/1       1   608 [.     1   673 []   628.7 5.7e-186
gi|67904160|ref|XP_682336.1|          1/1       1   610 [.     1   673 []   628.0   9e-186
gi|291186721|gb|EFE42141.1|           1/1       1   608 [.     1   673 []   627.4 1.4e-185
gi|119489357|ref|XP_001262889.1|      1/1       1   610 [.     1   673 []   616.3 3.1e-182
gi|70982294|ref|XP_746675.1|          1/1       1   610 [.     1   673 []   614.1 1.4e-181
gi|255954861|ref|XP_002568183.1|      1/1       1   608 [.     1   673 []   606.3 3.2e-179
gi|238843618|gb|EEQ33280.1|           1/1       1   608 [.     1   673 []   602.8 3.5e-178
gi|240107631|gb|EER25810.1|           1/1       1   619 [.     1   673 []   602.2 5.3e-178
gi|119177578|ref|XP_001240545.1|      1/1       1   619 [.     1   673 []   602.2 5.6e-178
gi|58262802|ref|XP_568811.1|          1/1       1   585 [.     1   673 []   597.5 1.4e-176
gi|256735483|gb|EEU48829.1|           1/1       1   599 [.     1   673 []   596.9 2.2e-176
gi|46107690|ref|XP_380904.1|          1/1       1   612 [.     1   673 []   591.1 1.2e-174
gi|50546531|ref|XP_500735.1|          1/1       1   638 [.     1   673 []   587.3 1.7e-173
gi|240281027|gb|EER44530.1|           1/1       1   620 [.     1   673 []   585.5 5.7e-173
gi|225562540|gb|EEH10819.1|           1/1       1   620 [.     1   673 []   583.0 3.3e-172
gi|226292756|gb|EEH48176.1|           1/1       1   622 [.     1   673 []   582.8 3.9e-172
gi|261205192|ref|XP_002627333.1|      1/1       1   617 [.     1   673 []   575.0 8.3e-170
gi|239611449|gb|EEQ88436.1|           1/1       1   617 [.     1   673 []   575.0 8.3e-170
gi|225680602|gb|EEH18886.1|           1/1       1   627 [.     1   673 []   570.5 1.8e-168
gi|39951367|ref|XP_363400.1|          1/1       1   611 [.     1   673 []   563.8   2e-166
gi|258564130|ref|XP_002582810.1|      1/1       1   606 [.     1   673 []   563.5 2.4e-166
gi|85116042|ref|XP_964984.1|          1/1       1   598 [.     1   673 []   557.4 1.7e-164
gi|121709055|ref|XP_001272292.1|      1/1       1   607 [.     1   673 []   548.8 6.5e-162
gi|289617909|emb|CBI55486.1|          1/1       1   610 [.     1   673 []   543.8 2.1e-160
gi|71014539|ref|XP_758725.1|          1/1     237   823 ..     1   673 []   540.0 2.9e-159
gi|171687657|ref|XP_001908769.1|      1/1       1   600 [.     1   673 []   538.3 9.4e-159
gi|156053868|ref|XP_001592860.1|      1/1       1   595 [.     1   673 []   538.3 9.6e-159
gi|169851344|ref|XP_001832362.1|      1/1       1   618 [.     1   673 []   537.0 2.4e-158
gi|242206537|ref|XP_002469124.1|      1/1       2   596 ..     1   673 []   521.3 1.2e-153
gi|39960084|ref|XP_364543.1|          1/1       1   611 [.     1   673 []   509.4 4.7e-150
gi|154279436|ref|XP_001540531.1|      1/1       1   617 [.     1   673 []   500.9 1.6e-147
gi|50557358|ref|XP_506087.1|          1/1       1   691 [.     1   673 []   498.6 8.5e-147
gi|170099658|ref|XP_001881047.1|      1/1       1   634 [.     1   673 []   476.3 4.2e-140
gi|169845161|ref|XP_001829300.1|      1/1       1   604 [.     1   673 []   473.0 4.3e-139
gi|169782124|ref|XP_001825525.1|      1/1       1   604 [.     1   673 []   458.8 8.2e-135
gi|116180482|ref|XP_001220090.1|      1/1       1   576 [.     1   673 []   456.8 3.1e-134
gi|238498984|ref|XP_002380727.1|      1/1       1   561 [.     1   673 []   423.7   3e-124
gi|46112807|ref|XP_383081.1|          1/1       1   610 [.     1   673 []   314.4  2.3e-91
gi|256721170|gb|EEU34581.1|           1/1       1   612 [.     1   673 []   309.6  6.3e-90
gi|226283048|gb|EEH38614.1|           1/1       1   519 [.     1   673 []   259.5  7.8e-75
gi|261356832|gb|EEY19260.1|           1/1       1   327 [.     1   673 []   166.3  8.7e-47
gi|242211740|ref|XP_002471707.1|      1/1       1   423 [.     1   673 []     5.3     0.76

Alignments of top-scoring domains:
gi|18376334|emb|CAD21080.1|: domain 1 of 1, from 1 to 651: score 1705.0, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+gLrigwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|1837633     1    MTGLRIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|1837633    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRiiaslsshlrralvWvLsFla+GYAteEFEvtEERLGvYRPEEHiDn
  gi|1837633    98 TIRIIASLSSHLRRALVWVLSFLAHGYATEEFEVTEERLGVYRPEEHIDN 147  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gYAD+kDAR+fD+RLRGPv+P+ELEiD++sGmKnYiAnE+layq+GWn
  gi|1837633   148 PLGYADGKDAREFDPRLRGPVHPGELEIDLYSGMKNYIANERLAYQQGWN 197  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +tsAGY+rfsl+R+iHFGRLYtsGsrg+GkEsDLCEALRCLGqALH+lED
  gi|1837633   198 TTSAGYIRFSLERCIHFGRLYTSGSRGRGKESDLCEALRCLGQALHTLED 247  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AHsnYCEL+Li++eerrgG+++vFpHvG+dt+i+lrndtrnnGk+v+P
  gi|1837633   248 FPAHSNYCELVLIDMEERRGGHSPVFPHVGTDTRITLRNDTRNNGKSVWP 297  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm++AL++Aeq++k+sgGG+s
  gi|1837633   298 LVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNDALLTAEQLTKGSGGGSS 347  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                   r+RGl+lfglnlgGs+s+++DFisLvs+lPgvGdG+AstARsLkAas+Aq
  gi|1837633   348 RDRGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDGYASTARSLKAASEAQ 397  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   Eq+nsr  +++nvnv               vPGmsPnFDpvkta+kiYPi
  gi|1837633   398 EQENSR--SAGNVNV---------------VPGMSPNFDPVKTAAKIYPI 430  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF+RPii+q
  gi|1837633   431 LEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFILGLLAPFLRPIINQ 480  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   v++vLKeGssgli++sA++qlEPWnnP+Cd+PtHsmLsKDHFtn+LnsCA
  gi|1837633   481 VTQVLKEGSSGLIATSAKQQLEPWNNPQCDNPTHSMLSKDHFTNILNSCA 530  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRvaa+ivqYvvPR++YAwenPGvP++Ev++D+L+vFHHPA+++EevEi+
  gi|1837633   531 GRVAANIVQYVVPRVVYAWENPGVPDSEVIADVLQVFHHPANYKEEVEIQ 580  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   r+m+etv++W+rEt  +h++++lL+sEsvKeghnHvl++q++d++   ++
  gi|1837633   581 RTMYETVVQWSRET--HHDYKTLLASESVKEGHNHVLNGQPMDRG---PG 625  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                   g+hts+GadgGHGkvaGslWski++r   
  gi|1837633   626 GGHTSCGADGGHGKVAGSLWSKIQSR    651  

gi|1261823|gb|AAB48349.1|: domain 1 of 1, from 1 to 640: score 1669.6, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+gLrigwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|1261823     1    MTGLRIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|1261823    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRii           vWvLsFla+GYAteEFEvtEERLGvYRPEEHiDn
  gi|1261823    98 TIRII-----------VWVLSFLAHGYATEEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gYAD+kDAR+fD+RLRGPv+P+ELEiD++sGmKnYiAnE+layq+GWn
  gi|1261823   137 PLGYADGKDAREFDPRLRGPVHPGELEIDLYSGMKNYIANERLAYQQGWN 186  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +tsAGY+rfsl+R+iHFGRLYtsGsrg+GkEsDLCEALRCLGqALH+lED
  gi|1261823   187 TTSAGYIRFSLERCIHFGRLYTSGSRGRGKESDLCEALRCLGQALHTLED 236  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AHsnYCEL+Li++eerrgG+++vFpHvG+dt+i+lrndtrnnGk+v+P
  gi|1261823   237 FPAHSNYCELVLIDMEERRGGHSPVFPHVGTDTRITLRNDTRNNGKSVWP 286  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm++AL++Aeq++k+sgGG+s
  gi|1261823   287 LVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNDALLTAEQLTKGSGGGSS 336  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                   r+RGl+lfglnlgGs+s+++DFisLvs+lPgvGdG+AstARsLkAas+Aq
  gi|1261823   337 RDRGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDGYASTARSLKAASEAQ 386  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   Eq+nsr  +++nvnv               vPGmsPnFDpvkta+kiYPi
  gi|1261823   387 EQENSR--SAGNVNV---------------VPGMSPNFDPVKTAAKIYPI 419  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLL PF+RPii+q
  gi|1261823   420 LEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFILGLLGPFLRPIINQ 469  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   v++vLKeGssgli++sA++qlEPWnnP+Cd+PtHsmLsKDHFtn+LnsCA
  gi|1261823   470 VTQVLKEGSSGLIATSAKQQLEPWNNPQCDNPTHSMLSKDHFTNILNSCA 519  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRvaa+ivqYvvPR++YAwenPGvP++Ev++D+L+vFHHPA+++EevEi+
  gi|1261823   520 GRVAANIVQYVVPRVVYAWENPGVPDSEVIADVLQVFHHPANYKEEVEIQ 569  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   r+m+etv++W+rEt  +h++++lL+sEsvKeghnHvl++q++d++   ++
  gi|1261823   570 RTMYETVVQWSRET--HHDYKTLLASESVKEGHNHVLNGQPMDRG---PG 614  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                   g+hts+GadgGHGkvaGslWski++r   
  gi|1261823   615 GGHTSCGADGGHGKVAGSLWSKIQSR    640  

gi|171690006|ref|XP_001909935.1|: domain 1 of 1, from 1 to 620: score 1638.5, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      magLrigw+s+LLvlav+LivLP++AAAFGAGniPsiAqvEG+nwRH
  gi|1716900     1    MAGLRIGWSSALLVLAVILIVLPGQAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LK++AF++GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
  gi|1716900    48 GDIEDTLKDIAFLYGKKWTTMMVGRVYFGNWLRDYSQAVDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRii           vWvLsF+a+GYAteEFEvtEERLG+YRPEEHiDn
  gi|1716900    98 TIRII-----------VWVLSFMANGYATEEFEVTEERLGCYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DARk+D+RLRGPvdPrELEiDpr+GmKnYiAnEs    gGW 
  gi|1716900   137 PKDYADNQDARKYDTRLRGPVDPRELEIDPRTGMKNYIANES----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGY+r+s+aRaiHFGRLYtsG+++kG+EsDLCEALRCLGqALHc+ED
  gi|1716900   182 ATSAGYLRWSIARAIHFGRLYTSGTTHKGRESDLCEALRCLGQALHCMED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCELaLiel     Gy++vF+H+G++t+inl      nGkrvyP
  gi|1716900   232 FSAHSNYCELALIEL-----GYHNVFAHCGSSTQINL------NGKRVYP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdE+d+ALkaAeq+s+ss+G   
  gi|1716900   271 LVTGTFGAVDFLHSVLGEATDHFTQSEVDEIDIALKAAEQNSNSSSG--- 317  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    qRG+l       Gsgssg+DFisLvsqlP+vGdG+As+ARsLkAasaAq
  gi|1716900   318 -QRGFL-------GSGSSGPDFISLVSQLPSVGDGFASQARSLKAASAAQ 359  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   Eqqn++qltr+nvn+               vPGmsPnFDpvk++++iYPi
  gi|1716900   360 EQQNMQQLTRDNVNQ---------------VPGMSPNFDPVKVSGQIYPI 394  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivRsinnmi+KiPGLEsLlEkisEtLtaFiLgLLAPF+RPii+q
  gi|1716900   395 LEFRDKIVRSINNMISKIPGLESLLEKISETLTAFILGLLAPFIRPIIQQ 444  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   vskvLK+Gs+glie+sAnaqlEPWnnPrC+dPtHsmLsKDHFtnvLnsCA
  gi|1716900   445 VSKVLKDGSTGLIESSANAQLEPWNNPRCNDPTHSMLSKDHFTNVLNSCA 494  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRv++tivqYvvPRilYA+enPGvPvdEvlnDiLr+FHHPAardE+vEih
  gi|1716900   495 GRVSVTIVQYVVPRILYAFENPGVPVDEVLNDILRAFHHPAARDERVEIH 544  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   r+mfetv+kW++Etk+rhelns+LssEsvK++hnH+la++ss+ssrsvsa
  gi|1716900   545 RNMFETVRKWTQETKHRHELNSILSSESVKNHHNHILASNSSSSSRSVSA 594  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                   +sh++nG+d+GHG++aGslW+++kk+   
  gi|1716900   595 PSHGGNGCDHGHGRPAGSLWEQVKKQ    620  

gi|14029167|gb|AAK51159.1|: domain 1 of 1, from 1 to 627: score 1632.6, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+L++++gs+LL+++++LivLP++AAAFGAGniPsiA++EGkn+RH
  gi|1402916     1    MAFLIPHSGSFLLIACILLIVLPSPAAAFGAGNIPSIANIEGKNFRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKtvAFikG+KWt+mm++RvYFGnWLRDYsqAvDvGsLKGv+A+
  gi|1402916    48 GDIEDMLKTVAFIKGHKWTSMMIKRVYFGNWLRDYSQAVDVGSLKGVSAP 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsFl+fGYAt+EFEvtEERLGvYRPEEHiDn
  gi|1402916    98 TIRIL-----------VWVLSFLSFGYATAEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYADi+DAR+fDaRLRGP++P+ELEiDp+sGmKnYiAnEs    gGW 
  gi|1402916   137 PKGYADIEDARTFDARLRGPINPMELEIDPNSGMKNYIANES----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYv+fs+aR+iHFGRLYt+Gs+gkGkE+DLCEALRCLGqALHc+ED
  gi|1402916   182 ATSAGYVKFSFARSIHFGRLYTNGSHGKGKEEDLCEALRCLGQALHCMED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+el     GyrdvFpH+Ga++ein+      +G++vyP
  gi|1402916   232 FGAHTNYCELALREL-----GYRDVFPHCGANAEINI------RGHHVYP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsvLGEAtDHFtq+Ev+EmdlAL++A++a++s+gGGd+
  gi|1402916   271 LVTGTFGAVDFLHSVLGEATDHFTQTEVEEMDLALGGAQKAQQSGGGGDG 320  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    qRGl+       GsgssgtDF++L++q+Pg+G+GlAstAR+L+A+saAq
  gi|1402916   321 -QRGLF-------GSGSSGTDFAGLLAQIPGMGSGLASTARDLQAQSAAQ 362  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   E+qns+q+tra++n+fnappgstggppgpgvPGmsP+FD+v+takkiYPi
  gi|1402916   363 EYQNSNQQTRASGNTFNAPPGSTGGPPGPGVPGMSPDFDAVATAKKIYPI 412  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivR+inn+i+KiPGLEsL+E+isEtLt+FiL+LLAPFvRPiid+
  gi|1402916   413 LEFRDKIVRAINNTIAKIPGLESLVERISETLTVFILSLLAPFVRPIIDA 462  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   vs++LK+Gss+++easAn+q+EPWn+PrC+dPtHsmLsKDHF+nvLnsCA
  gi|1402916   463 VSDSLKKGSSTVVEASANSQFEPWNDPRCTDPTHSMLSKDHFSNVLNSCA 512  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRva+ti+qYv+PRilYAw+nPGvPvdEv+nDiLr+FHHPA+rdE+vEih
  gi|1402916   513 GRVASTILQYVTPRILYAWQNPGVPVDEVMNDILRTFHHPALRDEHVEIH 562  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   +kmf+tvk+Wi+E++n+++ln+lLssEsvK+g+nH+++dq+++++     
  gi|1402916   563 KKMFNTVKDWINEQPNAQGLNHLLSSESVKAGRNHSGSDQHDHNH----- 607  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                         G++gGHGk++Gs+Ws+ik+r   
  gi|1402916   608 ------GSLGGHGKTSGSIWSEIKTR    627  

gi|154322635|ref|XP_001560632.1|: domain 1 of 1, from 1 to 627: score 1631.2, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+L++++gs+LL+++++LivLP++AAAFGAGniPsiA++EGkn+RH
  gi|1543226     1    MAFLIPHSGSFLLIACILLIVLPSPAAAFGAGNIPSIANIEGKNFRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKtvAFikG+KWt+mm++RvYFGnWLRDYsqAvDvGsLKGv+A+
  gi|1543226    48 GDIEDMLKTVAFIKGHKWTSMMIKRVYFGNWLRDYSQAVDVGSLKGVSAP 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsFl+fGYAt+EFEvtEERLGvYRPEEHiDn
  gi|1543226    98 TIRIL-----------VWVLSFLSFGYATAEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD++DAR+fDaRLRGP++P+ELE+Dp+sGmKnYiAnEs    gGW 
  gi|1543226   137 PKGYADNEDARTFDARLRGPINPMELEVDPNSGMKNYIANES----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYv+fs+aR+iHFGRLYtsGs+gkGkE+DLCEALRCLGqALHc+ED
  gi|1543226   182 ATSAGYVKFSFARSIHFGRLYTSGSHGKGKEEDLCEALRCLGQALHCMED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+el     GyrdvFpH+Ga++ein+      +G++vyP
  gi|1543226   232 FGAHTNYCELALREL-----GYRDVFPHCGANAEINI------RGHHVYP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsvLGEAtDHFtq+Ev+EmdlAL++A++a++s+gGGd+
  gi|1543226   271 LVTGTFGAVDFLHSVLGEATDHFTQTEVEEMDLALGGAQKAQQSGGGGDG 320  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    qRGl+       GsgssgtDF++L++q+Pg+G+GlAstAR+L+A+saAq
  gi|1543226   321 -QRGLF-------GSGSSGTDFAGLLAQIPGMGSGLASTARDLQAQSAAQ 362  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   E+qns+q+tra++n+fnappgstggppgpgvPGmsP+FD+v+takkiYPi
  gi|1543226   363 EYQNSNQQTRASGNTFNAPPGSTGGPPGPGVPGMSPDFDAVATAKKIYPI 412  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivR+inn+i+KiPGLEsL+E+isEtLt+FiL+LLAPFvRPiid+
  gi|1543226   413 LEFRDKIVRAINNTIAKIPGLESLVERISETLTVFILSLLAPFVRPIIDA 462  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   vs++LK+Gss+++easAn+q+EPWn+PrC+dPtHsmLsKDHF+nvLnsCA
  gi|1543226   463 VSDSLKKGSSTVVEASANSQFEPWNDPRCTDPTHSMLSKDHFSNVLNSCA 512  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRva+ti+qYv+PRilYAw+nPGvPvdEv+nDiLr+FHHPA+rdE+vEih
  gi|1543226   513 GRVASTILQYVTPRILYAWQNPGVPVDEVMNDILRTFHHPALRDEHVEIH 562  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   +kmf+tvk+Wi+E++n+++ln+lLssEsvK+g+nH+++dq+++++     
  gi|1543226   563 KKMFNTVKDWINEQPNAQGLNHLLSSESVKAGRNHSGSDQHDHNH----- 607  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                         G++gGHGk++Gs+Ws+ik+r   
  gi|1543226   608 ------GSLGGHGKTSGSIWSEIKTR    627  

gi|6425089|gb|AAF08294.1|AF195874_1: domain 1 of 1, from 1 to 650: score 1600.4, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      magL+igwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|6425089     1    MAGLKIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|6425089    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRii           vWvLsFla+GYAteEFEvtEERLGvYRPEEHiDn
  gi|6425089    98 TIRII-----------VWVLSFLAHGYATEEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gYAD+kDAR++D+RLRGPv+P ELEiDp++GmKnYiAnE la+++GWn
  gi|6425089   137 PLGYADGKDAREYDPRLRGPVHPAELEIDPNTGMKNYIANEELAHHQGWN 186  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +tsAGY+rfsl+R+iH+GRLYtsGs+g+GkEsDLCEALRCLGqALH+lED
  gi|6425089   187 TTSAGYIRFSLQRCIHYGRLYTSGSHGRGKESDLCEALRCLGQALHTLED 236  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnn......
                   F+AHsnYCEL+Li++eerrgG+++vFpHvG+ t++ l n    + +++++
  gi|6425089   237 FPAHSNYCELVLIDMEERRGGHSPVFPHVGTATKLKLENRQFRRvrpgeg 286  

                   ....GkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeq
                    +++ k  +PLvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm++AL++Aeq
  gi|6425089   287 ydsgAKYAWPLVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNDALLTAEQ 336  

                   askssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstA
                   ++k+sgGG+sr+RGl+lfglnlgGs+s+++DFisLvs+lPgvGdG+AstA
  gi|6425089   337 LTKGSGGGSSRDRGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDGYASTA 386  

                   RsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDp
                   RsLkAas+AqEq+nsr  +++nvnv               vPGmsPnFDp
  gi|6425089   387 RSLKAASEAQEQENSR--SAGNVNV---------------VPGMSPNFDP 419  

                   vktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLL
                   vkta+kiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLL
  gi|6425089   420 VKTAAKIYPILEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFILGLL 469  

                   APFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKD
                   APF+RPii+qv++vLKeGssgli++sA++qlEPWnnP Cd+PtHsmLsKD
  gi|6425089   470 APFLRPIINQVTQVLKEGSSGLIATSAKQQLEPWNNPDCDNPTHSMLSKD 519  

                   HFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHP
                   HFtn+LnsCAGRvaa+ivqYvvPR++YAwenPGvP++Ev++D+L+vFHHP
  gi|6425089   520 HFTNILNSCAGRVAANIVQYVVPRVVYAWENPGVPDSEVIADVLQVFHHP 569  

                   AardEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladq
                   A+++ e+Ei+r+m++tv++W+rEt  +h++++lL sEsvKeghnHvl++q
  gi|6425089   570 ANYKQEIEIQRTMYDTVVQWSRET--HHNYKKLLDSESVKEGHNHVLNGQ 617  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +++++   ++g+hts+GadgGHGkvaGslWski++r   
  gi|6425089   618 PMNRG---PGGGHTSCGADGGHGKVAGSLWSKIQSR    650  

gi|156064873|ref|XP_001598358.1|: domain 1 of 1, from 1 to 626: score 1593.5, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+L +  gs+LL+++++LivLP++AAAFGAGniPsi ++EGkn+RH
  gi|1560648     1    MAFLTPNTGSFLLIACILLIVLPGPAAAFGAGNIPSISNIEGKNFRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKtvAFikG+KWt+mm++RvYFGnWLRDYsqAvDvGsLKGv+A+
  gi|1560648    48 GDIEDMLKTVAFIKGHKWTSMMIKRVYFGNWLRDYSQAVDVGSLKGVSAP 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsFl+fGYAt+EFEvtEERLGvYRPEEHiDn
  gi|1560648    98 TIRIL-----------VWVLSFLSFGYATAEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD++DAR+fD+RLRGP++P ELEiDp++GmKnYiAnEs    gGW 
  gi|1560648   137 PKGYADNQDARTFDPRLRGPINPVELEIDPNTGMKNYIANES----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYv+fs+aR+iHFGRLYtsGs+gkGkE+DLCEALRCLGqALHc+ED
  gi|1560648   182 ATSAGYVKFSFARSIHFGRLYTSGSHGKGKEEDLCEALRCLGQALHCMED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+el     GyrdvFpH+Ga++ein+      +G++vyP
  gi|1560648   232 FGAHTNYCELALREL-----GYRDVFPHCGANAEINI------RGHHVYP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsvLGEA+DHFtq+Ev+EmdlAL++A++a++s+gG d+
  gi|1560648   271 LVTGTFGAVDFLHSVLGEANDHFTQTEVEEMDLALGGAQKAQQSGGG-DG 319  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    qRGl+       GsgssgtDF++L+sq+Pg+G GlAstAR+L+A+saAq
  gi|1560648   320 -QRGLF-------GSGSSGTDFVGLLSQIPGMGGGLASTARDLQAQSAAQ 361  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   E+qns+qltra++n+fnappgstggppgpgvPGmsP+FDpv+takkiYPi
  gi|1560648   362 EYQNSNQLTRADGNTFNAPPGSTGGPPGPGVPGMSPDFDPVATAKKIYPI 411  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivR+inn+i+KiPGLEsL+EkisEtLt+FiL+LLAPFvRPiid+
  gi|1560648   412 LEFRDKIVRAINNTIAKIPGLESLVEKISETLTVFILSLLAPFVRPIIDA 461  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   vs++L++Gss+++easAn+q+EPWn+P+C+dPtHsmLsKDHF+nvLnsCA
  gi|1560648   462 VSDSLRKGSSTVVEASANSQFEPWNDPHCTDPTHSMLSKDHFSNVLNSCA 511  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRva+ti+qYv+PRil+Aw+nPGvPvdEv+nDiLr+FHHPA+rdE+vEi+
  gi|1560648   512 GRVASTILQYVTPRILFAWQNPGVPVDEVMNDILRTFHHPALRDEHVEIQ 561  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   +kmf+tvk W++E++n++ ln++L sEsvK+g+nH +++q+++++     
  gi|1560648   562 KKMFDTVKSWVKEQPNAQSLNHVLGSESVKAGRNHTGSEQHDHNH----- 606  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                         Ga+gGHGk++Gs+Ws+ik+r   
  gi|1560648   607 ------GALGGHGKTSGSIWSEIKTR    626  

gi|289614135|emb|CBI61504.1|: domain 1 of 1, from 1 to 633: score 1537.2, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      magLrigwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|2896141     1    MAGLRIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|2896141    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRii           vWvLsFla+GYAteEFEvtEERLGvYRPEEHiDn
  gi|2896141    98 TIRII-----------VWVLSFLAHGYATEEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEsla.yqgGW
                   P+gYAD+kDAR++D+RLRGPvdPrELEiD  +GmKnYiAnE  a+ ++GW
  gi|2896141   137 PLGYADGKDAREYDPRLRGPVDPRELEIDRFTGMKNYIANEAAAnAHDGW 186  

                   natsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclE
                   ++tsAGY+r+sl R++H+GRLYtsGs+gkGkEsDLCEALRCLGqALH++E
  gi|2896141   187 KTTSAGYIRYSLRRCVHYGRLYTSGSHGKGKESDLCEALRCLGQALHTFE 236  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AHsnYCELaLie+     G++ vFpHvG+dt++ l    r nGk vy
  gi|2896141   237 DFPAHSNYCELALIEM-----GHSTVFPHVGTDTKVHL----RTNGKWVY 277  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm+ AL+ Ae ++k+sg G+
  gi|2896141   278 PLVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNNALLNAEVLTKGSGTGS 327  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   sr  Gl+lfglnlgGs+s+++DFisLvs+lPgvGd +AstARsLkAas+A
  gi|2896141   328 SRGGGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDNYASTARSLKAASEA 377  

                   qEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYP
                   qEq+n   ++++nvn                vPGmsPnFDpvkta+kiYP
  gi|2896141   378 QEQENNS-RSAGNVNI---------------VPGMSPNFDPVKTAAKIYP 411  

                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiid
                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF+RPii+
  gi|2896141   412 ILEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFILGLLAPFLRPIIN 461  

                   qvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsC
                   qv++vLKeGssgli++sA++qlEPW nP+Cd+PtHsmLsKDHFtn+LnsC
  gi|2896141   462 QVTQVLKEGSSGLIATSAKQQLEPWDNPQCDNPTHSMLSKDHFTNILNSC 511  

                   AGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEi
                   AGRvaati+qYvvPR++YAwenPGvPvdE++ D+LrvFHHPA+r+E ++i
  gi|2896141   512 AGRVAATILQYVVPRVVYAWENPGVPVDEMIDDVLRVFHHPANRNEGIDI 561  

                   hrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvs
                   +r m++tv +W+++t  + ++++lL s+ vKeghnHvl++q++d++   +
  gi|2896141   562 QRMMYDTVYQWSKDT--HYDWKTLLRSDKVKEGHNHVLNGQPMDRG---P 606  

                   agshtsnGadgGHGkvaGslWskikkr<-*
                   +g+ht++GadgGHGkvaGslWski++r   
  gi|2896141   607 GGGHTGCGADGGHGKVAGSLWSKIQTR    633  

gi|6425091|gb|AAF08295.1|AF196305_1: domain 1 of 1, from 1 to 638: score 1531.3, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+gLrigwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|6425091     1    MTGLRIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|6425091    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRii           vWvLsFla+GYAteEFEvtEERLGvYRPEEHiDn
  gi|6425091    98 TIRII-----------VWVLSFLAHGYATEEFEVTEERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gYAD+kDAR++D+RLRGPv+P ELEiDp++GmKnYiAnE la+++ W+
  gi|6425091   137 PLGYADGKDAREYDPRLRGPVHPAELEIDPNTGMKNYIANEELAHRERWD 186  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +tsAGY+rfsl+R+iH+GRLYtsGs+g+GkEsDLCEALRCLGqALH+lED
  gi|6425091   187 TTSAGYIRFSLQRCIHYGRLYTSGSHGRGKESDLCEALRCLGQALHTLED 236  

                   FsAHsnYCELaLieleerrg.GyrdvFpHvGadteinlrndtrnnGkrvy
                   F+AHsnYCELaLi+++e+  +  + +FpHvG+ t+i+l     nnGk v+
  gi|6425091   237 FPAHSNYCELALIDIHEKETrSESRIFPHVGTATRITL-----NNGKLVW 281  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm++AL++Aeq++k+sgGG+
  gi|6425091   282 PLVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNDALLTAEQLTKGSGGGS 331  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   sr+RGl+lfglnlgGs+s+++DFisLvs+lPgvGdG+AstARsLkAas+A
  gi|6425091   332 SRDRGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDGYASTARSLKAASEA 381  

                   qEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYP
                   qE +nsr  +++nvnv               vPGmsPnFDpvkta+kiYP
  gi|6425091   382 QEEENSR--SAGNVNV---------------VPGMSPNFDPVKTAAKIYP 414  

                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiid
                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF+LgLLAPF+RPii+
  gi|6425091   415 ILEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFVLGLLAPFLRPIIN 464  

                   qvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsC
                   qv++vLKeGssgli++sA +qlEPWn+ + d+PtH mLsKD FtnvLnsC
  gi|6425091   465 QVTQVLKEGSSGLIATSASQQLEPWNDRQWDNPTHCMLSKDQFTNVLNSC 514  

                   AGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEi
                   AGRv ati+qYvvPR++YAwenPGvP  Ev+ D+L+v HHPA+ + ++Ei
  gi|6425091   515 AGRVGATILQYVVPRVVYAWENPGVPEYEVIDDVLQVLHHPANVNPRIEI 564  

                   hrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvs
                   +  m++tvk+W +E k+   l++lLssEsvKeg nH+l++qs +++   +
  gi|6425091   565 QCMMYNTVKQWRQEFKDMGRLEQLLSSESVKEGLNHILNGQSTNRG---P 611  

                   agshtsnGadgGHGkvaGslWskikkr<-*
                   +g+hts+G dgGHGkvaGslWs+ik+r   
  gi|6425091   612 GGGHTSCGGDGGHGKVAGSLWSQIKNR    638  

gi|164427442|ref|XP_955880.2|: domain 1 of 1, from 1 to 612: score 1500.3, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+gLrigwgsvLLvla+vL+vLPdkAAAFGAGniPsiAqvEG+nwRH
  gi|1644274     1    MTGLRIGWGSVLLVLALVLVVLPDKAAAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFi+GkKWttmmvgR+YFGnWLRDYsqA+DvGsLKGvnAa
  gi|1644274    48 GDIEDVLKTLAFINGKKWTTMMVGRTYFGNWLRDYSQAIDVGSLKGVNAA 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRiiaslsshlrralv   sF                            
  gi|1644274    98 TIRIIASLSSHLRRALV---SF---------------------------H 117  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+         +  +RLRGPv+P+ELEiD++sGmKnYiAnE+layq+GWn
  gi|1644274   118 PL---------TLVTRLRGPVHPGELEIDLYSGMKNYIANERLAYQQGWN 158  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +tsAGY+rfsl+R+iHFGRLYtsGsrg+GkEsDLCEALRCLGqALH+lED
  gi|1644274   159 TTSAGYIRFSLERCIHFGRLYTSGSRGRGKESDLCEALRCLGQALHTLED 208  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AHsnYCEL+Li++eerrgG+++vFpHvG+dt+i+lrndtrnnGk+v+P
  gi|1644274   209 FPAHSNYCELVLIDMEERRGGHSPVFPHVGTDTRITLRNDTRNNGKSVWP 258  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG+vDFLHsvLGEA+DHFtqsEvdEm++AL++Aeq++k+sgGG+s
  gi|1644274   259 LVTGTFGGVDFLHSVLGEANDHFTQSEVDEMNDALLTAEQLTKGSGGGSS 308  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                   r+RGl+lfglnlgGs+s+++DFisLvs+lPgvGdG+AstARsLkAas+Aq
  gi|1644274   309 RDRGLSLFGLNLGGSSSNDGDFISLVSKLPGVGDGYASTARSLKAASEAQ 358  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   Eq+nsr  +++nvnv               vPGmsPnFDpvkta+kiYPi
  gi|1644274   359 EQENSR--SAGNVNV---------------VPGMSPNFDPVKTAAKIYPI 391  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF+RPii+q
  gi|1644274   392 LEFRDKIVRSINNMIEKIPGLESLLEKISETLTAFILGLLAPFLRPIINQ 441  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                   v++vLKeGssgli++sA++qlEPWnnP+Cd+PtHsmLsKDHFtn+LnsCA
  gi|1644274   442 VTQVLKEGSSGLIATSAKQQLEPWNNPQCDNPTHSMLSKDHFTNILNSCA 491  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRvaa+ivqYvvPR++YAwenPGvP++Ev++D+L+vFHHPA+++EevEi+
  gi|1644274   492 GRVAANIVQYVVPRVVYAWENPGVPDSEVIADVLQVFHHPANYKEEVEIQ 541  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvsa
                   r+m+etv++W+rEt  +h++++lL+sEsvKeghnHvl++q++d++   ++
  gi|1644274   542 RTMYETVVQWSRET--HHDYKTLLASESVKEGHNHVLNGQPMDRG---PG 586  

                   gshtsnGadgGHGkvaGslWskikkr<-*
                   g+hts+GadgGHGkvaGslWski++r   
  gi|1644274   587 GGHTSCGADGGHGKVAGSLWSKIQSR    612  

gi|116200111|ref|XP_001225867.1|: domain 1 of 1, from 1 to 623: score 1427.6, E = 0
                   *->magLrigwgsvLLvlav.vLivLPdkAAAFGAGniPsiAqvEGknwR
                      ma  r+gwg +LLv+a + L    +kAAAFGAGniPsiAqvEG+nwR
  gi|1162001     1    MANFRPGWGNALLVVAFtALWFFLEKAAAFGAGNIPSIAQVEGHNWR 47   

                   HGDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnA
                   HGDiED+LKtvAF++GkKWttmm+gRvYFGnWLRDYsqA+DvGsLKG+nA
  gi|1162001    48 HGDIEDMLKTVAFLHGKKWTTMMIGRVYFGNWLRDYSQAIDVGSLKGINA 97   

                   atiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiD
                   atiRii           vWvLsF+a+GYAteEFEvtEERLGvYRPEEHiD
  gi|1162001    98 ATIRII-----------VWVLSFMANGYATEEFEVTEERLGVYRPEEHID 136  

                   nPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGW
                   nP+gYAD kDAR++D+RLRGP++PrELEiDpr+GmKnYiAnEs    gGW
  gi|1162001   137 NPRGYADDKDAREYDPRLRGPINPRELEIDPRTGMKNYIANES----GGW 182  

                   natsAGYvrfslaRaiHFGRLYtsGsrgk.GkEsDLCEALRCLGqALHcl
                    atsAGY+r+s+aR+iHF R+YtsG+ g +GkE DLCEALRCLGqALHc+
  gi|1162001   183 -ATSAGYLRWSFARSIHFARVYTSGAGGTsGKEADLCEALRCLGQALHCM 231  

                   EDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrv
                   ED++AH+nYCELaLiel     G++ vFpH+G+ t+i l      nGk+v
  gi|1162001   232 EDWGAHTNYCELALIEL-----GHHSVFPHCGSATQIHL------NGKSV 270  

                   yPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGG
                   yPLvtGtFGavDFLHsvLGEAtDHFtqsEvdE+d+ALk Aeqa++ss+G 
  gi|1162001   271 YPLVTGTFGAVDFLHSVLGEATDHFTQSEVDEIDIALKNAEQANNSSSG- 319  

                   dsrqRGlllfglnlgGsgs.sgtDFisLvsqlPgvGdGlAstARsLkAas
                      qRG++       Gsgs+ g+DFis++ qlPgvGdG+As+AR+LkAas
  gi|1162001   320 ---QRGFF-------GSGSgGGGDFISMLGQLPGVGDGFASQARDLKAAS 359  

                   aAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakki
                   aAqE++n+r   + n+n                +PGmsPnFDpvk++++i
  gi|1162001   360 AAQERENAR--DASNANI---------------MPGMSPNFDPVKVSGQI 392  

                   YPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPi
                   YPi+ FRD+ivRsinnmi+K+PGLEsLlE+isEtLtaFiLgLLAPFvRPi
  gi|1162001   393 YPIMQFRDRIVRSINNMISKVPGLESLLEHISETLTAFILGLLAPFVRPI 442  

                   idqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLn
                   i+qvsk+LKeGssgli++sA++q+EPW nPrC dPtHsmLsKDHFtn+Ln
  gi|1162001   443 INQVSKALKEGSSGLIATSAQQQFEPWSNPRCSDPTHSMLSKDHFTNILN 492  

                   sCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEev
                   sC GRv++ti+qYvvPRi+YAwenPGvPvdEvl DiLr+FHHPAar++++
  gi|1162001   493 SCGGRVSVTILQYVVPRIMYAWENPGVPVDEVLDDILRAFHHPAARNDQI 542  

                   EihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrs
                   Ei+r+mfetv+kW++Et+ r  l+++LssEsvK+++nHvl+++  ++s s
  gi|1162001   543 EIQREMFETVRKWAQETPYRSRLDHMLSSESVKNHKNHVLSGEAGSRSVS 592  

                   vsagshtsn..GadgGHGkvaGslWskikkr<-*
                     +g  +++++G+dgGHGk+aGslWs+i++    
  gi|1162001   593 GGGGHPGGCghGSDGGHGKPAGSLWSHIQSV    623  

gi|256732973|gb|EEU46321.1|: domain 1 of 1, from 1 to 635: score 1358.1, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m       gs LL+ av Li LP+kA AFGAGniPsiAqvEG+nwRH
  gi|2567329     1    MPSFSLPRGSWLLLFAVCLILLPGKANAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L t+AF++GkKWt+m+++R+YFGnWLRDYsqAvD+GsLKGvnA 
  gi|2567329    48 GDIEDMLETIAFLNGKKWTSMLIKRTYFGNWLRDYSQAVDIGSLKGVNAE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsF+a+GYAteEFEvt +RLGvYRPEEHiDn
  gi|2567329    98 TIRIL-----------VWVLSFMAHGYATEEFEVTADRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gY D+ DAR+fD RLRGPv+  E  iDpr+GmKnYiAnE     g W 
  gi|2567329   137 PLGYGDGVDARTFDKRLRGPVEKIETQIDPRTGMKNYIANEN----GNW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y+rfs+aR+iHFGRLYt+G++ kG+E+DLCEALRCLGqALH++ED
  gi|2567329   182 ATSAAYLRFSFARSIHFGRLYTNGAK-KGREEDLCEALRCLGQALHTMED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCELaL+el     Gy+ vFpH+Ga teinl      +GkrvyP
  gi|2567329   231 FSAHSNYCELALREL-----GYHSVFPHCGAGTEINL------HGKRVYP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsv+GEA DHFtqsEvdE+d+ALk Ae  + ++ GG+s
  gi|2567329   270 LVTGTFGAVDFLHSVIGEASDHFTQSEVDEVDIALKNAEGTKSGGNGGSS 319  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    +R l+     + G +s  tDF++Lvs+lPgvGdG+As+AR+L+A s+Aq
  gi|2567329   320 -ERSLF---GGFLGISSTPTDFVGLVSKLPGVGDGFASQARDLQANSEAQ 365  

                   Eqqnsr......qltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                   E+qn   +++++ l+r+n+n+               vPGmsPnFDpvk+a
  gi|2567329   366 ERQNRSyqgtrgDLSRDNANQ---------------VPGMSPNFDPVKVA 400  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   ++iYPiLEFRDK+v++i   i+K+PGLE LlEkisEtLtaFiLgLLAPF+
  gi|2567329   401 GQIYPILEFRDKVVKAISRGIAKVPGLEKLLEKISETLTAFILGLLAPFI 450  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                   RPii+qvskvLK+Gssg+i asAn+q+EPW nPrCddPtHsmLsKDHFtn
  gi|2567329   451 RPIINQVSKVLKDGSSGVITASANSQYEPWDNPRCDDPTHSMLSKDHFTN 500  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAard
                   +LnsCAGR+aati+qY vPR+lYAwenP v vdE+ nD+Lr+FHHPAard
  gi|2567329   501 ILNSCAGRIAATILQYTVPRVLYAWENPRVSVDEICNDVLRAFHHPAARD 550  

                   EevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssds
                   E+vEi+r+m+ tvkkW+ E ++rhel +lLssEsvK+++nH+l++  +  
  gi|2567329   551 EHVEIQRDMYRTVKKWADEHPRRHELAHLLSSESVKNHKNHILNQSAHRG 600  

                   srsvsags.htsnG..adgGHGkvaGslWskikkr<-*
                   + s  ag +h++ G+ ++ GHGkvaGslWs++k+r   
  gi|2567329   601 GGSGGAGCnHGTFGdmSNLGHGKVAGSLWSHVKTR    635  

gi|67772310|gb|AAY79377.1|: domain 1 of 1, from 1 to 636: score 1349.6, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m    +  gs LL++av Li LP+kA AFGAGniPsiAqvEG+nwRH
  gi|6777231     1    MPSFSMPRGSWLLLIAVCLILLPGKAEAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L t+AF++GkKWt+m+++R+YFGnWLRDYsqAvD+GsLKGvnA 
  gi|6777231    48 GDIEDMLETIAFLHGKKWTSMLIKRTYFGNWLRDYSQAVDIGSLKGVNAE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsF+a+GYAt EFEvt +RLGvYRPEEHiDn
  gi|6777231    98 TIRIL-----------VWVLSFMAHGYATGEFEVTSDRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gY D+ DAR+fD RLRGPv+  E EiD r+GmKnYiAnE     g W 
  gi|6777231   137 PLGYGDGVDARTFDKRLRGPVEKIETEIDSRTGMKNYIANEN----GNW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y+r+s+aR+iH+GRLYtsGs+ kG E+DLCEALRCLGqALH++ED
  gi|6777231   182 ATSAAYLRYSFARSIHYGRLYTSGSK-KGNEDDLCEALRCLGQALHTMED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCELaL+el     Gy+ vFpH+Ga tei l      +GkrvyP
  gi|6777231   231 FSAHSNYCELALREL-----GYHSVFPHCGAHTEIHL------HGKRVYP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsv+GEA DHFtqsEvdE+d+ALk Ae as+ sgGG +
  gi|6777231   270 LVTGTFGAVDFLHSVIGEASDHFTQSEVDEVDVALKNAEGASNRSGGGGG 319  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    +R ll     + G  ss +DFi+Lvs+lPgvGdG+A++AR+LkA s+Aq
  gi|6777231   320 GERSLL---GGFLGIKSSPSDFIGLVSKLPGVGDGFAAQARDLKASSEAQ 366  

                   Eqqnsr.qltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYP
                   Eq+n+  q+tr++               +  vPGmsP+FDpv+ta+kiYP
  gi|6777231   367 EQRNMSyQQTRGDLSR----------DNANQVPGMSPDFDPVETARKIYP 406  

                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiid
                   iLEFRDKiv++i   i+K+PGLE LlEkisEtLtaFiLgLLAPF+RPii+
  gi|6777231   407 ILEFRDKIVKAISRGISKVPGLEKLLEKISETLTAFILGLLAPFIRPIIN 456  

                   qvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsC
                   qvskvLK+Gssg+i asA++q+EPW nP+C dPtHsmLsKDHFtn+LnsC
  gi|6777231   457 QVSKVLKDGSSGVITASAKSQYEPWDNPQCSDPTHSMLSKDHFTNILNSC 506  

                   AGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEi
                   AGR+aati+qY vPR+lYAwen Gv vdEv+nD+Lr+FHHPAard+++Ei
  gi|6777231   507 AGRIAATILQYTVPRVLYAWENTGVSVDEVVNDVLRAFHHPAARDDHIEI 556  

                   hrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsvs
                   +r+mf+tvkkW+ E ++rhel +lLss+svK+++nH+l+ q + +srs+ 
  gi|6777231   557 QRDMFKTVKKWADEHPRRHELAHLLSSDSVKNHKNHILN-QVQGNSRSIG 605  

                   ags..htsnG..adgGHGkvaGslWskikkr<-*
                   +g+ +h++ G+ a+ GHGkvaGslWs++k+r   
  gi|6777231   606 GGGcnHGTFGdmANAGHGKVAGSLWSQVKTR    636  

gi|46121569|ref|XP_385339.1|: domain 1 of 1, from 1 to 635: score 1336.1, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m    +  gs LL++av Li LP+kA AFGAGniPsiAqvEG+nwRH
  gi|4612156     1    MPSFSMPRGSWLLLIAVCLILLPGKAEAFGAGNIPSIAQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L t+AF++GkKWt+m+++RvYFGnWLRDYsqAvD+GsLKGvn  
  gi|4612156    48 GDIEDMLETIAFLHGKKWTSMLIKRVYFGNWLRDYSQAVDIGSLKGVNGE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vWvLsF+a+GYAt EFEvt +RLGvYRPEEHiDn
  gi|4612156    98 TIRIL-----------VWVLSFMAHGYATGEFEVTADRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gY D+ DAR+fD RLRGPv+P E EiDpr+GmKnYiAnE     gGW 
  gi|4612156   137 PLGYGDGLDARTFDKRLRGPVEPVETEIDPRTGMKNYIANEN----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y+r+slaR++H+GRLYtsGs  kG E+DLCEALRCLGqALH+lED
  gi|4612156   182 ATSAAYLRYSLARSVHYGRLYTSGSS-KGNEDDLCEALRCLGQALHTLED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCELaL+el     Gy+ vFpH+G  tei l      +GkrvyP
  gi|4612156   231 FSAHSNYCELALREL-----GYHSVFPHCGEHTEIKL------HGKRVYP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAe..qaskssgGG
                   LvtGtFGavDFLHsv+GEA DHFtqsEvdE+d+ALk Ae++ a++ssgGG
  gi|4612156   270 LVTGTFGAVDFLHSVIGEASDHFTQSEVDEVDVALKNAEggSANRSSGGG 319  

                   d.srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAas
                   ++s   G+l       G  s  +DFi+Lvs+lPgvGdGlAs+AR+LkA s
  gi|4612156   320 ErSLLGGFL-------GIKSTPGDFIGLVSKLPGVGDGLASQARDLKASS 362  

                   aAqEqqn.srqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   +AqEq+n+s q++r+n               +  vPGmsP+FDpv+ta+k
  gi|4612156   363 EAQEQRNrSYQQSRGNMTR----------DNANQVPGMSPDFDPVETARK 402  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   iYPiLEFRDKiv++i   i+K+PGLE LlEkisEtLtaFiLgLLAPF+RP
  gi|4612156   403 IYPILEFRDKIVKAISRGIAKVPGLEKLLEKISETLTAFILGLLAPFIRP 452  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qvskvLK+Gss++i asA++q+EPW nP C dPtHsmLsKDHFtn+L
  gi|4612156   453 IIQQVSKVLKDGSSSVITASAKSQYEPWDNPSCSDPTHSMLSKDHFTNIL 502  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEe
                   nsCAGR+aati+qY vPR+lYAwen Gv vdEv+nDiLr+FHHPAard++
  gi|4612156   503 NSCAGRIAATILQYTVPRVLYAWENTGVSVDEVVNDILRAFHHPAARDDH 552  

                   vEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssr
                   vEi+r+mf+t+k+W+ E ++rhel +lLssEsv++++nH+l++ s  s  
  gi|4612156   553 VEIQRDMFKTMKNWADEHPRRHELAHLLSSESVRNHKNHILNQVSGASR- 601  

                   svsags..htsnG..adgGHGkvaGslWskikkr<-*
                   sv +g+ +h++ G+ ++ GHGkvaGslWs++k+r   
  gi|4612156   602 SVGGGGcnHGTFGdmSNAGHGKVAGSLWSQVKTR    635  

gi|145607013|ref|XP_361445.2|: domain 1 of 1, from 1 to 579: score 1140.3, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma  ++ wg vLLvl +vL+v+P+kAAAFGAGniPsi qvEG+nwRH
  gi|1456070     1    MAISQVRWGTVLLVLGIVLVVMPGKAAAFGAGNIPSISQVEGHNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L+t+ F+kGkKW +  + RvYFGnWLRDYsqAvDvGsLKGvnA 
  gi|1456070    48 GDIEDMLQTLLFLKGKKWSSKNISRVYFGNWLRDYSQAVDVGSLKGVNAE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   t+Ri+           vWvLsFl+fGYAt+EFEvt +RLGvYRPEEHiDn
  gi|1456070    98 TVRIL-----------VWVLSFLSFGYATAEFEVTADRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   P+gY D+kDAR+fD+RLRGPvdPrELE+Dpr+GmKnYiAnEs    gGW 
  gi|1456070   137 PLGYGDGKDAREFDPRLRGPVDPRELEVDPRTGMKNYIANES----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats GY+rfs+aR+iHFGR+Yt Gsr  GkE+DLCEALRCLGqALHc+ED
  gi|1456070   182 ATSVGYLRFSFARCIHFGRVYTHGSRS-GKEEDLCEALRCLGQALHCMED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCELaL+el     G +dv+pH+G++teinl      nG+rvyP
  gi|1456070   231 FSAHSNYCELALREL-----GNHDVYPHCGTSTEINL------NGRRVYP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFGavDFLHsv+GEAtD  tqsEvdEm+ AL +A+  +k ++G d+
  gi|1456070   270 LVTGTFGAVDFLHSVIGEATDNLTQSEVDEMNEALISAQNITKPGAG-DG 318  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                     R l+      g sg s + FisL+ +lPgvG+G+As+AR L+A+saAq
  gi|1456070   319 -SRSLF------GSSGDSTSGFISLIDKLPGVGNGFASEARALQAESAAQ 361  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   +qqn   l+ra  n+               vPGmsP+FD+v+takkiYPi
  gi|1456070   362 DQQNQT-LSRA--NQ---------------VPGMSPDFDAVATAKKIYPI 393  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   L FRDKivR+i  +i+KiPG+E LlE+i EtLtaF+LgLLAP        
  gi|1456070   394 LAFRDKIVRAISDTISKIPGMEKLLERIGETLTAFVLGLLAP-------- 435  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                                                         KDHFtnvLnsCA
  gi|1456070   436 --------------------------------------KDHFTNVLNSCA 447  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   GRva+t++qYvvPR+l+Aw+nPGvPvdEv+nD++r+FHHPAar+E+++i+
  gi|1456070   448 GRVASTVLQYVVPRVLFAWDNPGVPVDEVVNDVIRAFHHPAARNEQIDIQ 497  

                   rkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssrsv..
                   ++mfetv+kW++E    h +  lLssEsvK+g+nHvla+ +   + s+++
  gi|1456070   498 KQMFETVRKWSNES---HHVIRLLSSESVKAGKNHVLANGQTATK-SLgg 543  

                   .sagshtsnGa.......dgGHGkvaGslWskikkr<-*
                   + + +h+ +G +    +++gGHGkv+GslWs++k+r   
  gi|1456070   544 hDGHAHGPTGFpaaamreLGGHGKVSGSLWSQVKTR    579  

gi|159129974|gb|EDP55088.1|: domain 1 of 1, from 1 to 639: score 1083.2, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+  +     +L+v+a++L+ LP +  AFGAGni si  vEGknwRH
  gi|1591299     1    MTRRMSPGFNALIVVALLLVLLPAQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG LK   A 
  gi|1591299    48 GDIEDMLKTIAFIKGHKWTSTMVKRVYFGNWLRDYSQAMDVGTLKSLPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsFl+fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|1591299    98 TIRIL-----------VWILSFLSFGYATAEFEVTSERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D+RLRGP+   ELEiDp++GmKnYiAnE+    g W 
  gi|1591299   137 PKDYADNQDARQYDSRLRGPIRQVELEIDPQTGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats  Y+++slaR+iH+GRLYtsG ++kGkE+DLCEALRCLGq LH+lED
  gi|1591299   182 ATSTAYIKYSLARSIHYGRLYTSGGHHKGKEEDLCEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH Ga te+n+      +G+rv+P
  gi|1591299   232 FAAHTNYCELALREM-----GFRNVFPHTGAATEMNI------RGHRVFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+   +ssgG  s
  gi|1591299   271 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQ--ANSSGGSLS 318  

                   rqRGlllfg........lnlgGsgssgtDFisLvsqlPgvGdGlA.stAR
                      Gll  g+ +++++ +  +      +D      q  g   G+A+ t R
  gi|1591299   319 AFTGLL--GkipgtkdlIAEAEELKRRSDAQQYANQHGGQRTGYAhETSR 366  

                   sLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpv
                    L     A  ++  + l+ra++      p ++ggp gpg PGm P+FDp 
  gi|1591299   367 GLDSYGSAVGRDLGESLSRASGPS---QPSTSGGPAGPGLPGM-PDFDPK 412  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   kt ++iYPiL FRD +vR +  +ieKiPGLE+L+Ek+ EtLt+F+++LLA
  gi|1591299   413 KTVAQIYPILQFRDNVVRKLSSIIEKIPGLEALVEKVTETLTIFVMSLLA 462  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PF+RPii++ s++L+ Gss++i+as + q+EPW nP+C+dPtHsmLsKDH
  gi|1591299   463 PFIRPIINAASNSLQAGSSSVIDASGKHQFEPWTNPHCTDPTHSMLSKDH 512  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPA
                   F+n+Ln  AGRva++i++Yv PR+lYAwe P vP + vl D LrvFHHPA
  gi|1591299   513 FSNILNEPAGRVASAILKYVAPRVLYAWEHPEVPEQQVLDDCLRVFHHPA 562  

                   ardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladq
                   +rd + E hr+mfe v++W++ +++r+  ln +LssE v++g+n  ++  
  gi|1591299   563 LRDMHNEAHRTMFEAVQNWAHSRPDRgASLNDILSSEGVRAGKNNGGEVG 612  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +s+ s        t+  a+gG  +++ + +++ +     
  gi|1591299   613 HSHAS--------TGFAALGGN-RPSHAAYQQQHPP    639  

gi|119482037|ref|XP_001261047.1|: domain 1 of 1, from 1 to 660: score 1081.6, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+  +     +L+v+a++L+ LP++  AFGAGni si  vEGknwRH
  gi|1194820     1    MTRRMSPGFNALIVVALLLVLLPSQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG LK   A 
  gi|1194820    48 GDIEDMLKTIAFIKGHKWTSTMVKRVYFGNWLRDYSQAMDVGTLKSLPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsFl+fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|1194820    98 TIRIL-----------VWILSFLSFGYATAEFEVTSERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++DaRLRGP+   EL+iDp++GmKnYiAnE+    g W 
  gi|1194820   137 PKDYADNQDARQYDARLRGPIRQVELDIDPQTGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats  Y+++slaR+iH+GRLYtsG +++GkE+DLCEALRCLGq LH+lED
  gi|1194820   182 ATSTAYIKYSLARSIHYGRLYTSGGHHRGKEEDLCEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH Ga te+n+      +G++v+P
  gi|1194820   232 FAAHTNYCELALREM-----GFRNVFPHTGAATEMNI------RGHHVFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+   +ssgG  s
  gi|1194820   271 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQ--ANSSGGSLS 318  

                   rqRGlllfglnlgGsgssgtDFisLvsql.............PgvGdGlA
                      Gll       G      D i+   +l+++++ ++  +++ g   G+A
  gi|1194820   319 AFTGLL-------GKIPGTKDLIAQAEELkrrseaqqyanqhSGQRTGYA 361  

                   .stARsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsP
                   + t R L     A  ++  + l+ra++      p ++ggp gpg PGm P
  gi|1194820   362 hETSRGLDDYGSAIGRDLGESLSRASGPS---QPSTSGGPAGPGLPGM-P 407  

                   nFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFi
                   +FDp kt ++iYPiL FRD +vR +  +ieKiPGLE L++k+ EtLt+F+
  gi|1194820   408 DFDPKKTVAQIYPILQFRDNVVRKLSSIIEKIPGLETLVDKVTETLTVFV 457  

                   LgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsm
                   ++LLAPF+RPii++ s++L+ Gssg+i+as + q+EPW +P+C+dPtHsm
  gi|1194820   458 MSLLAPFIRPIINAASNSLQAGSSGVIDASGKHQFEPWTDPHCTDPTHSM 507  

                   LsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrv
                   LsKDHF+n+Ln  AGRva++i++Yv PR+lYAwe P vP + vl D Lrv
  gi|1194820   508 LSKDHFSNILNEPAGRVASAILKYVAPRVLYAWEHPEVPEQQVLDDCLRV 557  

                   FHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnH
                   FHHPA+rd + E hr+mfe v++W++ +++r+  ln +LssE v++g+n 
  gi|1194820   558 FHHPALRDMHNEAHRTMFEAVQNWAHSRPDRgASLNDILSSEGVRAGKNN 607  

                   vladqssdssrsvsa.....gshtsnGadgGHGkv......aGsl.Wski
                    ++  +s+ s   +a +++++sh++      H +++++++++ sl+W+++
  gi|1194820   608 GGEVGHSHASTGFAAfggnkPSHAAHQQHPPHQQPhpqqqqSSSLpWDQL 657  

                   kkr<-*
                    k    
  gi|1194820   658 SKL    660  

gi|71002476|ref|XP_755919.1|: domain 1 of 1, from 1 to 639: score 1079.1, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+  +     +L+v+a++L+ LP +  AFGAGni si  vEGknwRH
  gi|7100247     1    MTRRMSPGFNALIVVALLLVLLPAQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG LK   A 
  gi|7100247    48 GDIEDMLKTIAFIKGHKWTSTMVKRVYFGNWLRDYSQAMDVGTLKSLPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsFl+fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|7100247    98 TIRIL-----------VWILSFLSFGYATAEFEVTSERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D+RLRGP+   ELEiDp++GmKnYiAnE+    g W 
  gi|7100247   137 PKDYADNQDARQYDSRLRGPIRQVELEIDPQTGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats  Y+++slaR+iH+GRLYtsG ++kGkE+DLCEALRCLGq LH+lED
  gi|7100247   182 ATSTAYIKYSLARSIHYGRLYTSGGHHKGKEEDLCEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH Ga te+n+      +G+rv+P
  gi|7100247   232 FAAHTNYCELALREM-----GFRNVFPHTGAATEMNI------RGHRVFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+   +ssgG  s
  gi|7100247   271 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQ--ANSSGGSLS 318  

                   rqRGlllfg........lnlgGsgssgtDFisLvsqlPgvGdGlA.stAR
                      Gll  g+ +++++ +  +      +D      q  g   G+A+ t R
  gi|7100247   319 AFTGLL--GkipgtkdlIAEAEELKRRSDAQQYANQHGGQRTGYAhETSR 366  

                   sLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpv
                    L     A  ++  + l+ra++      p ++ggp gpg PGm P+FDp 
  gi|7100247   367 GLDSYGSAVGRDLGESLSRASGPS---QPSTSGGPAGPGLPGM-PDFDPK 412  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   kt ++iYPiL FRD +vR +  +ieKiPGLE+L+Ek+ EtLt+F+++LLA
  gi|7100247   413 KTVAQIYPILQFRDNVVRKLSSIIEKIPGLEALVEKVTETLTIFVMSLLA 462  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PF+RPii++ s++L+ Gss++i+as + q+EPW nP+C+dPtHsmLsKDH
  gi|7100247   463 PFIRPIINAASNSLQAGSSSVIDASGKHQFEPWTNPHCTDPTHSMLSKDH 512  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPA
                   F+n+Ln  AGRva++i++Yv PR+lYAwe P vP + vl D L vFHHPA
  gi|7100247   513 FSNILNEPAGRVASAILKYVAPRVLYAWEHPEVPEQQVLDDCLCVFHHPA 562  

                   ardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladq
                   +rd + E hr+mfe v++W++ +++r+  ln +LssE v++g+n  ++  
  gi|7100247   563 LRDMHNEAHRTMFEAVQNWAHSRPDRgASLNDILSSEGVRAGKNNGGEVG 612  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +s+ s        t+  a+gG  +++ + +++ +     
  gi|7100247   613 HSHAS--------TGFAALGGN-RPSHAAYQQQHPP    639  

gi|121716642|ref|XP_001275868.1|: domain 1 of 1, from 1 to 649: score 1075.0, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma  +  +  +LLv+a++L+ LP++  AFGAGni si  vEGknwRH
  gi|1217166     1    MARGMGLSFNALLVVALLLVLLPSQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ m++RvYFGnWLRDYsqA+DvG LK + A 
  gi|1217166    48 GDIEDMLKTIAFIKGHKWTSSMIKRVYFGNWLRDYSQAMDVGTLKSIPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsF++fGYAt+E+Evt +RLGvYRPEEHiDn
  gi|1217166    98 TIRIL-----------VWILSFMTFGYATAEYEVTLDRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D+RLRGPv   EL+iDp++GmKnYiAnE+    g W 
  gi|1217166   137 PKDYADNQDARQYDSRLRGPVRRVELDIDPQTGMKNYIANEQ----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats  Y+++slaR+iH+GRLYtsG + kG E+DL EALRCLGq LH+lED
  gi|1217166   182 ATSTAYIKYSLARSIHYGRLYTSG-HRKGNEEDLNEALRCLGQGLHTLED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH Ga te+nl      +G+rv+P
  gi|1217166   231 FAAHTNYCELALREM-----GFRNVFPHTGAATEMNL------HGHRVFP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+   +ssgG  +
  gi|1217166   270 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQ--ANSSGGSLA 317  

                   rqRGlllfglnlgGsgssgtDFisLvsql.............PgvGdGlA
                      Gll       G      D +s   +l+++++ ++  +++ g  +G+A
  gi|1217166   318 AFTGLL-------GKIPGTRDLVSQAEELkrrseaqqyanqhAGQRSGYA 360  

                   st..ARsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGms
                   s+++ R     s   +++  + ++ra++      p s+gg  gpg PG+ 
  gi|1217166   361 SQesSRGFDDYSSGVDRDFGESRSRASGSN---RPSSSGGSAGPGLPGL- 406  

                   PnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF
                   P+FDp kt  +iYPiLEFRD +vR +  +ieKiPGLEsL+EkisEtLt+F
  gi|1217166   407 PDFDPSKTVSQIYPILEFRDNVVRKLSAIIEKIPGLESLVEKISETLTVF 456  

                   iLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHs
                   +++LLAPF+RPii++ sk+L+ Gssg+ieas + q+EPW +P+C+dPtHs
  gi|1217166   457 VMSLLAPFIRPIINAASKSLQTGSSGVIEASGEHQFEPWTDPHCTDPTHS 506  

                   mLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr
                   mLsKDHF+nvLn  AGRva++i++Yv PR+lYAwe   vP++ vl+D Lr
  gi|1217166   507 MLSKDHFSNVLNEPAGRVASAILKYVAPRVLYAWEHTEVPDQQVLEDCLR 556  

                   vFHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghn
                   +FHHPA+rd + E hr+mfe v+ W++ +++r+ +ln +LssE vK g+n
  gi|1217166   557 IFHHPALRDMRNEAHRTMFEAVEAWAHSRPRRgADLNDILSSEGVKTGKN 606  

                   HvladqssdssrsvsagshtsnGadgGH.GkvaGslWskikkr<-*
                     ++  +s+ + s   ++ ++n   +GH+G+   s   + + +   
  gi|1217166   607 NGGQVGHSHGGGSSGFPALGGNKPSHGHgGHQQYSSHHQSQPQ    649  

gi|258573359|ref|XP_002540861.1|: domain 1 of 1, from 1 to 635: score 1052.2, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m     g   + Lvlav+L+ LP++  AFGAGni si +vEGknwRH
  gi|2585733     1    MGSYTAGIRPAFLVLAVLLVLLPSHVHAFGAGNIASISKVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDvLKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG L+  +  
  gi|2585733    48 GDIEDVLKTLAFIKGHKWTSNMVKRVYFGNWLRDYSQAMDVGTLQKLQSE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vW+LsF++fGYAt EFEvt ERLGvYRPEEHiDn
  gi|2585733    98 TIRVL-----------VWILSFMSFGYATGEFEVTAERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD+kDAR++D RLRGPv   ELE+Dp++GmKnYiAnE+    g W 
  gi|2585733   137 PKDYADNKDARQYDQRLRGPVRQIELEVDPETGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYvr+s+aR+iHFGRLY +G ++kG+E+DLCEALRCLGq LH+lED
  gi|2585733   182 ATSAGYVRYSFARSIHFGRLYANGGHHKGREEDLCEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+n+CEL+L+e+     G ++vFpH G+ t +n+      +Gk+v+P
  gi|2585733   232 FGAHTNFCELVLREM-----GMHNVFPHTGTRTMMNI------RGKHVFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsE+dE d AL++A qas ssg    
  gi|2585733   271 LVTGTFGMVDFFHSVLGEATDHFTQSEIDEADNALGSA-QASGSSGP--- 316  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                      Gl                  sL+ ++Pg+Gd l  +A +L+ +s+Aq
  gi|2585733   317 -LNGLT-----------------SLLGKVPGMGD-LVTEAQQLQHQSQAQ 347  

                   Eqqnsrqltranvnv....fnappgst....ggppgpgvPGmsPnFDpvk
                    q n + ++   +   +++fn  p s + +        vPG+ P+FDp k
  gi|2585733   348 AQANQQYQSHHGGYGvsrgFNDGPHSQpagySDDTRANVPGV-PDFDPQK 396  

                   takkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAP
                   t  +iYPiL FRDK+vR i  +++KiPGLEsL++kisEtLt+Fi +LLAP
  gi|2585733   397 TISQIYPILVFRDKVVRRISAVVSKIPGLESLMDKISETLTVFIYSLLAP 446  

                   FvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHF
                   FvRP+i   s+ L  Gss +i++sA+ q+EPW +P C+dPtHs+LsKDHF
  gi|2585733   447 FVRPLITFASQKLHLGSSEVIQSSAQHQFEPWTDPTCTDPTHSLLSKDHF 496  

                   tnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAa
                   +n+Ln  AG vaa+i+++ vPR+lYAw+n   Pvd vlnD + vFHHPA+
  gi|2585733   497 SNILNEPAGNVAAAILKFAVPRVLYAWQNVDFPVDHVLNDCMSVFHHPAL 546  

                   rdEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladq.
                   rd + E hr+mfe v++W++ +++r+  l+++Ls+EsvK+g+nH   + +
  gi|2585733   547 RDMQNEAHRTMFEAVQQWAHSRRDRgASLDHILSAESVKAGKNHTTGGAg 596  

                   ....ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +++++ + +    a +h+        G++  s  s+ +++   
  gi|2585733   597 hdhgHGHGHAHTHAHAHSQPHQAAPYGHPQAS-HSQGQSQ    635  

gi|145251257|ref|XP_001397142.1|: domain 1 of 1, from 1 to 606: score 1046.1, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma  +     +LLvl ++L+ LP +  AFGAGni si  vEGknwRH
  gi|1452512     1    MAPRMSLGTHALLVLGLLLVLLPTQTWAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+mmv+RvYFGnWLRDYsqA+DvG LK   A 
  gi|1452512    48 GDIEDMLKTIAFIKGHKWTSMMVKRVYFGNWLRDYSQAMDVGTLKSLPAE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsF++fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|1452512    98 TIRIL-----------VWILSFMTFGYATAEFEVTSERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR+fD RLRGPv   EL+iDp++GmKnYiAnE     gGW 
  gi|1452512   137 PKDYADNQDAREFDQRLRGPVRQVELDIDPETGMKNYIANEE----GGW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   ats  Y+++slaR+iH+GR Yt Gs+ kG E+DLCEALRCLGq LH+lED
  gi|1452512   182 ATSSAYIKYSLARSIHYGRTYTHGSK-KGNEEDLCEALRCLGQGLHTLED 230  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nY ELaL+e+     G+r+vFpH G +t++n+      +G++v+P
  gi|1452512   231 FAAHTNYIELALREM-----GFRNVFPHTGVNTQMNV------RGHHVFP 269  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEA+DHFtqsEv+Emd+AL+ Ae   +ssgG   
  gi|1452512   270 LVTGTFGMVDFFHSVLGEANDHFTQSEVNEMDIALGDAE--ANSSGG--- 314  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                                    s + F +L+  +Pg  d l  +A +Lk  s+Aq
  gi|1452512   315 -----------------SLGAFTGLLGNIPGTKD-LVEEAEELKRRSEAQ 346  

                   EqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYPi
                   E  n       n n     pg               +FDp kt ++iYPi
  gi|1452512   347 ESANRA-----NENE---RPGEDSQSGSAL-----QDFDPSKTIAQIYPI 383  

                   LEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidq
                   LEFRDK+vR +  +ieKiPGLE+++Eki EtLt+F+++LLAPF+RP+i++
  gi|1452512   384 LEFRDKVVRKLASIIEKIPGLEAIVEKITETLTVFVMSLLAPFIRPLINA 433  

                   vskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCA
                    sk+L+ Gssg+i+as + q+EPW +P C+dPtHs+LsKDHF+n+Ln  A
  gi|1452512   434 ASKSLQAGSSGVIDASGKHQYEPWTDPNCTDPTHSLLSKDHFSNILNEPA 483  

                   GRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEih
                   G va++i++Yv PR+lYAw+n  v +d vl+D L+vFHHPA+r+ + E h
  gi|1452512   484 GQVASAILKYVAPRVLYAWQNLDVSDDQVLEDCLKVFHHPALRNMNNEAH 533  

                   rkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqssdssrsvs
                   r+mf+ v+ W+  +++r+ +ln +Ls+E v++g+n  +++ +s+s+    
  gi|1452512   534 RTMFKAVQAWVDSRPDRgADLNDVLSAEGVRQGKNSTGEEGHSHSH---- 579  

                   agshtsnGadgGHGkvaGslWskikkr<-*
                   +g+ +++G  +G  +      ++ +++   
  gi|1452512   580 GGGFGAAGHSHGSQQQRPPQQQQQQQQ    606  

gi|67523423|ref|XP_659771.1|: domain 1 of 1, from 1 to 642: score 1041.8, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma       s LL l +vL+ LP +  AFGAGni si +vEGknwRH
  gi|6752342     1    MAPRLSFGLSTLLALGLVLLLLPCQVHAFGAGNIASISKVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG LK   A 
  gi|6752342    48 GDIEDMLKTIAFIKGHKWTSNMVKRVYFGNWLRDYSQAMDVGTLKSLPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsFl+fGYAt+EFEvt +RLGvYRPEEHiDn
  gi|6752342    98 TIRIL-----------VWILSFLSFGYATAEFEVTADRLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD+ DAR++D RLRGP+   ELEiDp++GmKnYiAnE+    g W 
  gi|6752342   137 PKDYADNLDARQYDQRLRGPIRQIELEIDPETGMKNYIANEK----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y+++slaR+iH+GRLYtsG + kG E+DL EALRCLGq LH+lED
  gi|6752342   182 ATSAAYIKYSLARSIHYGRLYTSGGHRKGNEEDLFEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+++vFpH G++t++n+      +G++vyP
  gi|6752342   232 FAAHTNYCELALREM-----GFHNVFPHTGTQTQMNI------RGHHVYP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEA DHFtqsE++Emd+AL+ A+  s + +  +s
  gi|6752342   271 LVTGTFGMVDFFHSVLGEASDHFTQSEINEMDIALGDAQSSSSANSL-NS 319  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l                  +L+ ++Pg Gd l ++A  Lk  s+Aq
  gi|6752342   320 ----LT-----------------GLLGKVPGCGD-LVAEAEALKRRSEAQ 347  

                   Eqqnsr....................qltranvnvfnappgstggppgpg
                      nsr++ + +   ++ +++ +++++++r+   +     + +g+    g
  gi|6752342   348 QSSNSRsgadlgyaagqftrsfnddsEQSRGVHEQ-SRADAPSGANKPTG 396  

                   vPGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisE
                    PGm P+F p +t +kiYPiLEFRDK+vR +  +ieKiPGLE+L+Eki E
  gi|6752342   397 LPGM-PDFNPAETIAKIYPILEFRDKVVRKVSSIIEKIPGLEALVEKITE 445  

                   tLtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCd
                   tLt+Fi++LLAPF+RPii++ sk+L+ Gs+g+ie+s + q+EPW nP+C+
  gi|6752342   446 TLTVFIMSLLAPFIRPIINAASKSLQTGSAGVIESSGKHQFEPWTNPHCT 495  

                   dPtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvl
                   dPtHsmLsKDHF+n+Ln  AG va++i++Yv+PR+l Awen  +  + vl
  gi|6752342   496 DPTHSMLSKDHFSNILNEPAGLVASAILKYVTPRVLHAWENINISEQQVL 545  

                   nDiLrvFHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsv
                    D L vFHHPA+r+ + E hr+mfe v+ W++  ++r+ +ln +LssE v
  gi|6752342   546 HDALEVFHHPALRNMRNEAHRTMFEAVQSWVHAMPDRgAKLNDILSSEGV 595  

                   KeghnHvladqssdssrsvsagshtsnGadgGHGkvaGsl.Wskikkr<-
                   K g+n  ++  + ++s    +g  +  Ga   HG+  Gs ++ +  ++  
  gi|6752342   596 KTGKNNGGQVGHGSHS-HAQGGFPALGGAAAAHGHSYGSHsYGQTSSH   642  

                   *
                    
  gi|6752342     -   -    

gi|115388269|ref|XP_001211640.1|: domain 1 of 1, from 1 to 631: score 1036.4, E = 0
                   *->mag.LrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwR
                      ma +Lr gw  +LL+la++L+ LP +A AFGAGni si  vEGknwR
  gi|1153882     1    MASpLRSGWN-ALLILALLLVLLP-QAHAFGAGNIASISAVEGKNWR 45   

                   HGDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnA
                   HGDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG LK   A
  gi|1153882    46 HGDIEDMLKTIAFIKGHKWTSNMVKRVYFGNWLRDYSQAMDVGTLKSLPA 95   

                   atiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiD
                    tiR++           vW+LsF++fGYAt+EFEvt ERLGvYRPEEHiD
  gi|1153882    96 DTIRVL-----------VWILSFMTFGYATAEFEVTAERLGVYRPEEHID 134  

                   nPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGW
                   nPk+YAD++DAR++D RLR P+   EL+iDp++GmKnYiAnE+    g W
  gi|1153882   135 NPKDYADNQDARQYDQRLRPPIRQVELDIDPHTGMKNYIANER----GDW 180  

                   natsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclE
                    atsAGYv++slaR+iH+GR+Yt G + kG E+DLCEALRCLGq LH+lE
  gi|1153882   181 -ATSAGYVKYSLARSIHYGRMYTHGGHRKGNEEDLCEALRCLGQGLHTLE 229  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nYCELaL+e+     G+++vFpH G+ t+inl      +G++v+
  gi|1153882   230 DFAAHTNYCELALREM-----GFHNVFPHTGSATQINL------HGRQVF 268  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG vDF Hs+LGEAtDHFtqsEv+Emd AL+ A+  s s++G  
  gi|1153882   269 PLVTGTFGMVDFFHSMLGEATDHFTQSEVNEMDTALGNAQSSSSSGSG-- 316  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                                          isL+ ++Pg  d l ++A +Lk  s+A
  gi|1153882   317 --------------------NALISLLGKIPGTKD-LVAQAEELKRRSEA 345  

                   qEqqnsr.........qltranvnvfnappgstggppgpgvPG..msPnF
                   q   n +++++++  ++ +ra +   ++ p  +  p     P ++    F
  gi|1153882   346 QQAANQHsgthsgyatEVSRAFGDS-DSTPHRASTPQSQSQPAqpATSSF 394  

                   DpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLg
                   Dp kt ++iYPiLEFRD++vR +  +ieKiPGLE+L+Eki E Lt+F+++
  gi|1153882   395 DPQKTIAQIYPILEFRDRVVRKLSSVIEKIPGLEALVEKITESLTVFVMS 444  

                   LLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLs
                   LLAPFvRP+i++ sk+L+ Gs+++i+as + q+EPW +P+C+dPtHs+Ls
  gi|1153882   445 LLAPFVRPLINAASKSLQSGSASVIDASGKHQFEPWTDPHCTDPTHSLLS 494  

                   KDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFH
                   KDHF+n+Ln  AG va++i++Yv+PR+l Aw+n  +P + vl D L+vFH
  gi|1153882   495 KDHFSNILNEPAGHVASAILKYVTPRVLHAWQNVDIPEQQVLDDCLHVFH 544  

                   HPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvl
                   HPA rd + E hr+m+e v+ W++ + +r+ +ln +Ls+E vK+g+n  +
  gi|1153882   545 HPAVRDMHNEAHRTMYEAVQGWVHSRSDRgAGLNDILSAEGVKAGKNNGG 594  

                   adqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +  +s+ +    + +h+++G      +  G+   + + +   
  gi|1153882   595 QVGHSHAQ--GQGHGHGGAGYSQTQAHGYGAPPAQHHYQ    631  

gi|240106324|gb|EER24517.1|: domain 1 of 1, from 1 to 626: score 1034.6, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m     g   + L++av+L+vLP++  AFGAGni si ++EGknwRH
  gi|2401063     1    MGSYTAGVKPAFLIIAVILVVLPSQVNAFGAGNIASISKIEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG L+  +  
  gi|2401063    48 GDIEDMLKTLAFIKGHKWTSNMVKRVYFGNWLRDYSQAMDVGTLQKLQSE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vW+LsF++fGYAt EFEvt ERLGvYRPEEHiDn
  gi|2401063    98 TIRVL-----------VWILSFMSFGYATGEFEVTAERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD+kDAR++DaRLRGPv   EL+iDp++GmKnYiAnE+    g W 
  gi|2401063   137 PKDYADNKDARQYDARLRGPVRQVELDIDPETGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYvr+s+aR+iHFGRLYt G + kG+E+DL EALRCLGq LH+lED
  gi|2401063   182 ATSAGYVRYSFARSIHFGRLYTKGGHKKGREEDLYEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCEL+L+e+     G  +vFpH G+ t +++      +Gk+++P
  gi|2401063   232 FGAHTNYCELVLREM-----GMYNVFPHTGTRTMMTV------RGKHIFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHF qsE+dE d A ++A+     ++G ++
  gi|2401063   271 LVTGTFGMVDFFHSVLGEATDHFAQSEIDEADNAFGSAQ-----ASGSSA 315  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                      Gl                   ++  +Pg+Gd l  +A +L+ +s+Aq
  gi|2401063   316 PLNGLT-----------------NMLGNVPGMGD-LITEAQQLQQQSQAQ 347  

                   Eqqnsrqltr....anvnvfnappgstg..........gppgpgvPGmsP
                    q n + ++ +++ +    fn      g +  ++++ +g  g  +PGm P
  gi|2401063   348 AQANQQYQSHhggyGASRGFNDDGHGQGagyyddtrapGQNGANIPGM-P 396  

                   nFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFi
                   +FDp kt  +iYPiL FRDK+vR +  ++eKiPGLEsL+EkisEtLt+F+
  gi|2401063   397 DFDPQKTVSQIYPILVFRDKVVRRVSSVVEKIPGLESLMEKISETLTVFV 446  

                   LgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsm
                    +LLAPFvRP+i   sk L  Gss +i++sA+ q+EPW +P+C+dPtHs+
  gi|2401063   447 YSLLAPFVRPLITFASKKLHLGSSEVINSSAQHQFEPWTDPHCTDPTHSL 496  

                   LsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrv
                   LsKDHF+n+Ln  AG vaa+i+++vvPR+lYAw+    Pvd vlnD + v
  gi|2401063   497 LSKDHFSNILNEPAGGVAAAILKFVVPRVLYAWQHADFPVDHVLNDCVSV 546  

                   FHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnH
                   FHHPA+rd   E hr+mfe v++W+  +++r+  l+++Ls+Esv++g+nH
  gi|2401063   547 FHHPALRDMDNEAHRTMFEVVQQWAFSRHDRgASLDHILSAESVRAGKNH 596  

                   vladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                      + + + +           G  +GHG+      s+ ++    
  gi|2401063   597 TVDGSHGHGH-----------GHSHGHGHGHVHAHSQPHQA    626  

gi|119191852|ref|XP_001246532.1|: domain 1 of 1, from 1 to 626: score 1032.2, E = 0
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m   + g   + L++av+L+ LP++  AFGAGni si ++EGknwRH
  gi|1191918     1    MGSYIAGVKPAFLIIAVILVLLPSQVNAFGAGNIASISKIEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ mv+RvYFGnWLRDYsqA+DvG L+  +  
  gi|1191918    48 GDIEDMLKTLAFIKGHKWTSNMVKRVYFGNWLRDYSQAMDVGTLQKLQSE 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vW+LsF++fGYAt EFEvt ERLGvYRPEEHiDn
  gi|1191918    98 TIRVL-----------VWILSFMSFGYATGEFEVTAERLGVYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD+kDAR++DaRLRGPv   EL+iD+++GmKnYiAnE+    g W 
  gi|1191918   137 PKDYADNKDARQYDARLRGPVRQVELDIDLETGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYvr+s+aR+iHFGRLYt G + kG+E+DL EALRCLGq LH+lED
  gi|1191918   182 ATSAGYVRYSFARSIHFGRLYTKGGHKKGREEDLYEALRCLGQGLHTLED 231  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCEL+L+e+     G  +vFpH G++t +++      +Gk+++P
  gi|1191918   232 FGAHTNYCELVLREM-----GMYNVFPHTGTKTMMTV------RGKHIFP 270  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHF qsE+dE d A ++A+     ++G ++
  gi|1191918   271 LVTGTFGMVDFFHSVLGEATDHFAQSEIDEADNAFGSAQ-----ASGSSA 315  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                      Gl                   ++  +Pg+Gd l  +A +L+ +s+Aq
  gi|1191918   316 PLNGLT-----------------NMLGNVPGMGD-LITEAQQLQQQSQAQ 347  

                   Eqqnsrqltr....anvnvfnappgstg..........gppgpgvPGmsP
                    q n + ++ +++ +    fn      g +  ++++ +g  g  +PGm P
  gi|1191918   348 AQANQQYQSHhggyGASRGFNDDGHGQGagyyddtrapGQNGANIPGM-P 396  

                   nFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFi
                   +FDp kt  +iYPiL FRDK+vR +  ++eKiPGLEsL+EkisEtLt+F+
  gi|1191918   397 DFDPQKTISQIYPILVFRDKVVRRVSSVVEKIPGLESLMEKISETLTVFV 446  

                   LgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsm
                    +LLAPFvRP+i   sk L  Gss +i++sA+ q+EPW +P+C+dPtHs+
  gi|1191918   447 YSLLAPFVRPLITFASKKLHLGSSEVINSSAQHQFEPWTDPHCTDPTHSL 496  

                   LsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrv
                   LsKDHF+n+Ln  AG vaa+i+++vvPR+lYAw+    Pvd vlnD + v
  gi|1191918   497 LSKDHFSNILNEPAGGVAAAILKFVVPRVLYAWQHADFPVDHVLNDCVSV 546  

                   FHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnH
                   FHHPA+rd + E hr+mfe v++W+  +++r+  l+++Ls+Esv++g+nH
  gi|1191918   547 FHHPALRDMNNEAHRTMFEVVQQWAFSRHDRgASLDHILSAESVRAGKNH 596  

                   vladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                      + + + +           G  +GHG+      s+ ++    
  gi|1191918   597 TVDGSHGHGH-----------GHSHGHGHGHVHAHSQPHQA    626  

gi|169762762|ref|XP_001727281.1|: domain 1 of 1, from 1 to 634: score 1011.8, E = 2.6e-301
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma        +LL++++vL+vLP++  AFGAGni si  vEGknwRH
  gi|1697627     1    MASGTNMGFNALLIICLVLVVLPSQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ m++RvYFGnWLRDYsqA+DvG LK v A 
  gi|1697627    48 GDIEDMLKTIAFIKGHKWTSTMIKRVYFGNWLRDYSQAMDVGTLKSVPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+L+F++fGYAt+EFEvt ERLG YRPEEHiDn
  gi|1697627    98 TIRIL-----------VWILAFMTFGYATAEFEVTSERLGTYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D+RLRGPv   EL+iDp++GmKnYiAnE+    g W 
  gi|1697627   137 PKDYADNEDARQYDSRLRGPVRQVELDIDPNTGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +ts GY+++sl R+iH+GRLYt      G E+DLCEALRCLGq LH+lED
  gi|1697627   182 STSSGYIKYSLSRSIHYGRLYT----RNGNEEDLCEALRCLGQGLHTLED 227  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH G  te+n+      +G+rvyP
  gi|1697627   228 FAAHTNYCELALREM-----GFRNVFPHTGQRTEMNV------RGHRVYP 266  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+ ++ s++  ++
  gi|1697627   267 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQTNTSSGSA-SA 315  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l                  +L+ ++Pg  d l  +A +Lk  s+ q
  gi|1697627   316 ----LT-----------------ALLGKVPGTKD-LVNQAEELKRRSDEQ 343  

                   Eqqnsr......qltranvnvf.nappgstggppg............pgv
                   E  n r++++++  tr++   +++   gs+ g  g++++  + ++++   
  gi|1697627   344 ESANRRggrrsgYSTRGSTRSYdDYDSGSSRGFGGersraaraddsnQTS 393  

                   PGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEt
                    G  P+FD+  t ++iYPiL FRD +vR +  +ie iPGLE L+E i Et
  gi|1697627   394 SGGLPDFDANNTIQQIYPILQFRDNVVRKLSSIIENIPGLETLVETITET 443  

                   LtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCdd
                   Lt+F+++LLAPFvRPii++ sk L+ Gss++i+as + q+EPW +P+C+d
  gi|1697627   444 LTVFVMSLLAPFVRPIINAASKQLQAGSSSVIDASGQHQYEPWTDPHCTD 493  

                   PtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvln
                   PtHs+LsKDHF+n+Ln  AG va++i++Yv PR+lYAwen  + +  v +
  gi|1697627   494 PTHSLLSKDHFSNILNEPAGQVASAILKYVAPRVLYAWENTNISDRQVAE 543  

                   DiLrvFHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvK
                   D L+vFHHPA+rd + E hr+m+e v+ W++ +++r+ eln +Ls+E vK
  gi|1697627   544 DCLQVFHHPALRDMRNEAHRTMYEAVESWVQSRPDRgSELNDILSAEGVK 593  

                   eghnHvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +g+n  +++ +s+ +    + sh s  a+  H +   s +   + +   
  gi|1697627   594 AGKNQTGEGGHSHGH----GHSH-SHAAQQSHTQSGQSQYRPPQYQ    634  

gi|238488583|ref|XP_002375529.1|: domain 1 of 1, from 1 to 634: score 1011.8, E = 2.6e-301
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma        +LL++++vL+vLP++  AFGAGni si  vEGknwRH
  gi|2384885     1    MASGTNMGFNALLIICLVLVVLPSQVHAFGAGNIASISAVEGKNWRH 47   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+LKt+AFikG+KWt+ m++RvYFGnWLRDYsqA+DvG LK v A 
  gi|2384885    48 GDIEDMLKTIAFIKGHKWTSTMIKRVYFGNWLRDYSQAMDVGTLKSVPAD 97   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+L+F++fGYAt+EFEvt ERLG YRPEEHiDn
  gi|2384885    98 TIRIL-----------VWILAFMTFGYATAEFEVTSERLGTYRPEEHIDN 136  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D+RLRGPv   EL+iDp++GmKnYiAnE+    g W 
  gi|2384885   137 PKDYADNEDARQYDSRLRGPVRQVELDIDPNTGMKNYIANER----GDW- 181  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   +ts GY+++sl R+iH+GRLYt      G E+DLCEALRCLGq LH+lED
  gi|2384885   182 STSSGYIKYSLSRSIHYGRLYT----RNGNEEDLCEALRCLGQGLHTLED 227  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nYCELaL+e+     G+r+vFpH G  te+n+      +G+rvyP
  gi|2384885   228 FAAHTNYCELALREM-----GFRNVFPHTGQRTEMNV------RGHRVYP 266  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEAtDHFtqsEv+Emd+AL+ A+ ++ s++  ++
  gi|2384885   267 LVTGTFGMVDFFHSVLGEATDHFTQSEVNEMDIALGDAQTNTSSGSA-SA 315  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l                  +L+ ++Pg  d l  +A +Lk  s+ q
  gi|2384885   316 ----LT-----------------ALLGKVPGTKD-LVNQAEELKRRSDEQ 343  

                   Eqqnsr......qltranvnvf.nappgstggppg............pgv
                   E  n r++++++  tr++   +++   gs+ g  g++++  + ++++   
  gi|2384885   344 ESANRRggrrsgYSTRGSTRSYdDYDSGSSRGFGGersraaraddsnQTS 393  

                   PGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEt
                    G  P+FD+  t ++iYPiL FRD +vR +  +ie iPGLE L+E i Et
  gi|2384885   394 SGGLPDFDANNTIQQIYPILQFRDNVVRKLSSIIENIPGLETLVETITET 443  

                   LtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCdd
                   Lt+F+++LLAPFvRPii++ sk L+ Gss++i+as + q+EPW +P+C+d
  gi|2384885   444 LTVFVMSLLAPFVRPIINAASKQLQAGSSSVIDASGQHQYEPWTDPHCTD 493  

                   PtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvln
                   PtHs+LsKDHF+n+Ln  AG va++i++Yv PR+lYAwen  + +  v +
  gi|2384885   494 PTHSLLSKDHFSNILNEPAGQVASAILKYVAPRVLYAWENTNISDRQVAE 543  

                   DiLrvFHHPAardEevEihrkmfetvkkWirEtknr.helnslLssEsvK
                   D L+vFHHPA+rd + E hr+m+e v+ W++ +++r+ eln +Ls+E vK
  gi|2384885   544 DCLQVFHHPALRDMRNEAHRTMYEAVESWVQSRPDRgSELNDILSAEGVK 593  

                   eghnHvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +g+n  +++ +s+ +    + sh s  a+  H +   s +   + +   
  gi|2384885   594 AGKNQTGEGGHSHGH----GHSH-SHAAQQSHTQSGQSQYRPPQYQ    634  

gi|255953065|ref|XP_002567285.1|: domain 1 of 1, from 1 to 627: score 1010.8, E = 5.5e-301
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m  L  + gs+LLvl   L++LP +  AFGAGni si  vEGknwRH
  gi|2559530     1    MPLL--HAGSALLVL---LLILP-QVHAFGAGNIASISAVEGKNWRH 41   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDv+Kt+AFi G+KWt+ m++RvYFGnWLRDYsqA+DvG LK  +A 
  gi|2559530    42 GDIEDVIKTLAFISGHKWTSTMIKRVYFGNWLRDYSQAMDVGTLKNLQAD 91   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vWvLsFl+fGYAt EFEvt +RLGvYRPEEHiDn
  gi|2559530    92 TIRVL-----------VWVLSFLSFGYATGEFEVTSDRLGVYRPEEHIDN 130  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D RLR Pv   ELEiDp +GmKnYiAnE+    g W 
  gi|2559530   131 PKDYADNEDARQYDKRLRPPVRAVELEIDPTTGMKNYIANER----GDW- 175  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y++fsl R+iH+GR Yt+G + kG E+DLCEALRCLGq LH+lED
  gi|2559530   176 ATSAAYIKFSLSRSIHYGRTYTNGGHKKGSEEDLCEALRCLGQGLHTLED 225  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AH+nY ELaL+e+     G+++vF H G+ teinl      +G+rv+P
  gi|2559530   226 FAAHTNYVELALREM-----GFKNVFTHTGTATEINL------QGRRVFP 264  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF Hsv+GEA DHFtqsEv+Emd+AL+ Aeq+ +s    ++
  gi|2559530   265 LVTGTFGMVDFFHSVMGEADDHFTQSEVNEMDIALGNAEQNAQSNNSLNA 314  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l                  +L+ ++Pg  d l s+A  Lk  saAq
  gi|2559530   315 ----LT-----------------GLLGKIPGTKD-LVSEAEGLKRSSAAQ 342  

                   Eqqnsrqltranvnv..fnappgstggppgpgvPGmsPnFDpvktakkiY
                      n  + +     +++fn+   + +gp       m P+  p +t +kiY
  gi|2559530   343 GMANQSRSSGTGYAQssFNSHERTRAGPTQSSGSSM-PDLNPQETVAKIY 391  

                   PiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPii
                   PiL FRDK++R +n +ieKiPGLEsL+EkisEtLt+Fi++LL PF+RP+i
  gi|2559530   392 PILAFRDKVMRKLNSVIEKIPGLESLVEKISETLTVFIMSLLSPFIRPLI 441  

                   dqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLns
                   ++ sk+++ Gs+g+i+as + q+EPW +P+C+dPtHs+LsKDHF+n+Ln 
  gi|2559530   442 KAASKSMQTGSAGVIDASGKHQYEPWTDPHCTDPTHSLLSKDHFANILNE 491  

                   CAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevE
                    AGRva+ iv YvvPR+lYAw+   vP  EvlnD ++vFHHPA+r+ + +
  gi|2559530   492 PAGRVASSIVEYVVPRVLYAWQHIDVPEHEVLNDCMQVFHHPALRNMRND 541  

                   ihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqss...ds
                    hr mfe v+kW++ + +r+  l+s+LssE v+ g+n  + ++ +++++ 
  gi|2559530   542 AHRAMFEAVEKWAHGRSDRgASLDSILSSEGVRSGRNTGGVSHTHtggHG 591  

                   srsvsagshtsnGadgGH....GkvaGslWskikkr<-*
                   + +  +g+  +    +GH++++G+ +G   s + ++   
  gi|2559530   592 GFAALGGASHGQSQSHGHsntgGHSSGGFSSFLPQQ    627  

gi|238845486|gb|EEQ35148.1|: domain 1 of 1, from 1 to 623: score 994.8, E = 3.6e-296
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m +        +L++av+L+vLP +  AFGAGni s+  +EGknwRH
  gi|2388454     1    MGF---NPTTTILLIAVLLVVLPARVEAFGAGNIASVSAIEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDv+Kt+AFikG+KWtt mv+RvYFGnWLRDYsqAvDvG LK v+  
  gi|2388454    45 GDIEDVIKTLAFIKGHKWTTNMVKRVYFGNWLRDYSQAVDVGTLKSVQSD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   t+Ri+           vWvLsF++fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|2388454    95 TVRIL-----------VWVLSFMTFGYATAEFEVTSERLGVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD  DAR++D+RLRGPv+  EL+iD ++GmKnYiAnE+    g W 
  gi|2388454   134 PKGYADDADARQYDPRLRGPVQQVELDIDRETGMKNYIANER----GNW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsr.gkGkEsDLCEALRCLGqALHclE
                   atsAGYv++s+aR+iHF R Y +G +  kGk++DL EALRCLGq LH+lE
  gi|2388454   179 ATSAGYVKYSFARSIHFARQYINGGHlRKGKDEDLYEALRCLGQGLHTLE 228  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nYCEL+L+e+     G  +vFpH G++t +n+      +Gk+++
  gi|2388454   229 DFGAHTNYCELVLREM-----GMLNVFPHTGTNTMMNI------RGKHIF 267  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG vDFLHsvLGEA DH tqsE++E+d  L+ Ae  s   g  +
  gi|2388454   268 PLVTGTFGMVDFLHSVLGEASDHVTQSEINELDNTLENAEVGSATTGSVN 317  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   +    l                  sL+s++Pg+Gd l ++A  LkA+s+A
  gi|2388454   318 T----LT-----------------SLLSKVPGMGD-LIAEAEKLKAQSQA 345  

                   qEqqnsrq.....ltranvnvfnappgstgg...ppgpgvPGmsPnFDpv
                   q q n   + + + +   vn      g+tgg ++    + PG  P  Dp 
  gi|2388454   346 QAQANNSAgygygGASRGVND-GQTYGATGGfdqTSRAAGPGGLPSIDPQ 394  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   kt  +iYPiL FRD +vR i  +++KiPGLEsL++ki +tL +F+ +LL 
  gi|2388454   395 KTVSQIYPILVFRDNVVRRISAVVSKIPGLESLVDKITDTLSVFVFSLLS 444  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PF+RP+i+  +  L+ Gssg+i +s + q+EPW +P C+dPtHs+LsKDH
  gi|2388454   445 PFIRPLIKVATSQLQTGSSGVISTSEQHQYEPWTDPMCTDPTHSLLSKDH 494  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPA
                   F+n+Ln  AG vaa+i++YvvPR++YAw+   +Pvd+vl+D +rvFHHPA
  gi|2388454   495 FSNILNEPAGHVAAAILKYVVPRVMYAWQHVDIPVDDVLADCMRVFHHPA 544  

                   ardEevEihrkmfetvkkWirEtkn.rhelnslLssEsvKeghnHvladq
                   +rd + E hr+mfe v++W+r ++++   l+++L + sv+eg+nH + + 
  gi|2388454   545 LRDMNNEAHRTMFEAVQNWARSRPDgGASLDTILNAQSVREGKNHKGGNP 594  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + + +      sh s G+ +G G + G+     +++   
  gi|2388454   595 HLHGN------SH-SHGSGHGYGNTVGAQQPMYHHQ    623  

gi|291178161|gb|EFE33952.1|: domain 1 of 1, from 1 to 634: score 983.5, E = 8.7e-293
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m +        +L++a++L+vLP +  AFGAGni s+  vEGknwRH
  gi|2911781     1    MGF---NPTTTILLVALLLVVLPARVEAFGAGNIASVSAVEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDv+Kt+AFikG+KWt+ mv+RvYFGnWLRDYsqAvDvG LK v A 
  gi|2911781    45 GDIEDVIKTLAFIKGHKWTANMVKRVYFGNWLRDYSQAVDVGTLKNVPAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                    +R++           vWvLsF++fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|2911781    95 SVRVL-----------VWVLSFMTFGYATAEFEVTSERLGVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD  DAR++D+RLRGPv+  ELEiD ++GmKnYiAnE+    g W 
  gi|2911781   134 PKGYADDADARQYDPRLRGPVQRVELEIDHETGMKNYIANER----GNW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsr.gkGkEsDLCEALRCLGqALHclE
                   atsAGYv++s+ R+iHF R Y +G +  +Gk++DL EALRCLGq LH+lE
  gi|2911781   179 ATSAGYVKYSFSRSIHFARQYINGGHlRRGKDEDLYEALRCLGQGLHTLE 228  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nYCELaL+e+     G  +vFpH G++t +n+      +Gk+++
  gi|2911781   229 DFGAHTNYCELALREM-----GMLNVFPHTGTNTMMNI------KGKHIF 267  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG vDFLHsvLGEA DH tqsE+ E+d  L+ Ae      g  +
  gi|2911781   268 PLVTGTFGMVDFLHSVLGEASDHVTQSEISELDTTLENAEVGGATTGSVN 317  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   +    l                  sL+s++Pg+Gd l ++A  LkA s+A
  gi|2911781   318 A----LT-----------------SLLSKVPGMGD-LIAEAEKLKASSQA 345  

                   qEqqnsrq......ltranvnvfnappgstgg..ppgpgvPGmsPnFDpv
                   q q ns+ + + ++ +r+          +tgg +    + PG  P  Dp 
  gi|2911781   346 QAQANSNAgygyggASRGLDDGQTQAYSATGGydQTSRAGPGGLPSVDPQ 395  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   k+  +iYPiL FRD +vR i  +++KiPGLEsL+Eki +tL +Fi +LL 
  gi|2911781   396 KVISQIYPILVFRDNVVRRISSVVSKIPGLESLVEKITDTLSVFIFSLLS 445  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PFvRP+i+  +  L+ Gssg+i +s + q+EPW +P C+dPtHs+LsKDH
  gi|2911781   446 PFVRPLIKVATSQLQTGSSGVISTSEQHQYEPWTDPNCTDPTHSLLSKDH 495  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPA
                   F+n+Ln  AG vaa+i++YvvPR+lYAw+   +Pvd+vl+D +rvFHHPA
  gi|2911781   496 FSNILNEPAGHVAAAILKYVVPRVLYAWQHVDIPVDDVLADCMRVFHHPA 545  

                   ardEevEihrkmfetvkkWirEtkn.rhelnslLssEsvKeghnHvladq
                   +rd + E hr+mfe v++W+r ++++   l+++L + sv+eg+nH + + 
  gi|2911781   546 LRDMNNEAHRTMFEAVQNWARSRRDgGASLDTILNAQSVREGKNHTGGNP 595  

                   ssdssrsvsagshts...nGadgGHGkvaGslWskikkr<-*
                   + + +    +++h+s+++ G +  HG + G      +++   
  gi|2911781   596 HLQGGGHGHGSGHGSghgYGQQPMHGGAHGYQPPYQQQQ    634  

gi|291187190|gb|EFE42589.1|: domain 1 of 1, from 1 to 624: score 972.8, E = 1.4e-289
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m +        +L++a++L+vLP +  AFGAGni s+  vEGknwRH
  gi|2911871     1    MGF---NPTTTILLIALLLVVLPARVEAFGAGNIASVSAVEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiEDv+Kt+AFikG+KWt+ mv+RvYFGnWLR YsqAvDvG LK v A 
  gi|2911871    45 GDIEDVIKTLAFIKGHKWTANMVKRVYFGNWLRYYSQAVDVGTLKNVPAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                    +R++           vWvLsF++fGYAt+EFEvt ERLGvYRPEEHiDn
  gi|2911871    95 SVRVL-----------VWVLSFMTFGYATAEFEVTSERLGVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD  DAR++D+RLRGPv+  ELEiD ++GmKnYiAnE+    g W 
  gi|2911871   134 PKGYADDADARQYDPRLRGPVQRVELEIDHETGMKNYIANER----GNW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsr.gkGkEsDLCEALRCLGqALHclE
                   atsA Yv++s+ R+iHF R Y +G +  +G ++DL EALRCLGq LH+lE
  gi|2911871   179 ATSAAYVKYSFSRSIHFARQYINGGHlRRGNDEDLYEALRCLGQGLHTLE 228  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nYCELaL+e+     G  +vFpH G++t +n+      +Gk+++
  gi|2911871   229 DFGAHTNYCELALREM-----GMLNVFPHTGTNTMMNI------KGKHIF 267  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG vDFLHsvLGEA DH tqsE+ E+d  L+ Ae      g  +
  gi|2911871   268 PLVTGTFGMVDFLHSVLGEASDHVTQSEISELDTTLENAEVGGATTGSVN 317  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   +    l                  sL+s++Pg+Gd l ++A  LkA s+A
  gi|2911871   318 A----LT-----------------SLLSKVPGMGD-LIAEAEKLKASSQA 345  

                   qEqqnsrq......ltranvnvfnappgstgg..ppgpgvPGmsPnFDpv
                   q q ns+ + + ++ +r+         g++gg +    + PG  P  Dp 
  gi|2911871   346 QAQANSNAgygyggASRGLDDGQTQAYGAAGGydQTSRAGPGGLPSVDPQ 395  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   k+  +iYPiL FRD +vR i  +++KiPGLEsL+Eki +tL +Fi +LL 
  gi|2911871   396 KVISQIYPILVFRDNVVRRISSVVSKIPGLESLVEKITDTLSVFIFSLLS 445  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PFvRP+i+  +  L+ Gssg+i +s + q+EPW +P C+dPtHs+LsKDH
  gi|2911871   446 PFVRPLIKVATSQLQTGSSGVISTSEQHQYEPWTDPNCTDPTHSLLSKDH 495  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPA
                   F+n+Ln  AG vaa+i++YvvPR+lYAw+   +Pvd+vl+D +rvFHHPA
  gi|2911871   496 FSNILNEPAGHVAAAILKYVVPRVLYAWQHVDIPVDDVLADCMRVFHHPA 545  

                   ardEevEihrkmfetvkkWirEtkn.rhelnslLssEsvKeghnHvladq
                   +rd + E hr+mfe v++W+r ++++   l+++L + sv+eg+nH + + 
  gi|2911871   546 LRDMNNEAHRTMFEAVQNWARSRRDgGASLDTILNAQSVREGKNHTGGNP 595  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + + +    + +h   G+ +G G+ +G  + +   +   
  gi|2911871   596 HLQGG----GHGH---GSGHGSGHGSGHGYGQQPMH    624  

gi|212535568|ref|XP_002147940.1|: domain 1 of 1, from 5 to 663: score 965.7, E = 2.1e-287
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                       a+      +++ v+ ++LivLP+kA AFGAGni si  +EGknwRH
  gi|2125355     5    -AFKSSSTTAFVFVVLLMLIVLPGKAEAFGAGNIASISTIEGKNWRH 50   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+++ +AFi+G+KWt+ m++RvYFGnWLRDYsqA+DvG LK  +A 
  gi|2125355    51 GDIEDTIQALAFIRGHKWTSAMIKRVYFGNWLRDYSQAMDVGTLKNLQAD 100  

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vW+LsF++fGYAt EFEvt +RLGvYRPEEHiDn
  gi|2125355   101 TIRVL-----------VWILSFMTFGYATGEFEVTSDRLGVYRPEEHIDN 139  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DAR++D RLR Pv   EL+iDp++GmKnYiAnE+    g W 
  gi|2125355   140 PKDYADNNDARQYDKRLRPPVRQIELDIDPETGMKNYIANEK----GDW- 184  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsA Y+++s+ R+iH+GRLYt+G   kGkE+DL EALRCLGq LH+lED
  gi|2125355   185 ATSAAYIKYSISRSIHYGRLYTNGGNNKGKEEDLFEALRCLGQGLHTLED 234  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   F+AHsnYCEL+L+e+     G+++vFpHvG  teinl      +Gkrv+P
  gi|2125355   235 FGAHSNYCELVLREM-----GFHNVFPHVGVATEINL------RGKRVFP 273  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   LvtGtFG vDF HsvLGEA+DHFtqsE +E d  L++Ae +++s +  ++
  gi|2125355   274 LVTGTFGMVDFFHSVLGEANDHFTQSELNEADNTLLGAESNTQSPAI-NA 322  

                   rqRGlllfglnlgGsgssgtDFisLv..sqlPg.......vGdGlA....
                      Gll    ++ G     t+   L ++s + ++ +++++v  G+A++++
  gi|2125355   323 -LTGLL---GKVPGTKELITEAEELQrrSNMQAeanrnrhVHTGYAtsrg 368  

                   ....stARsLkAasaAqEqqnsrqltr.........anvnvfnappgstg
                    ++ st  s +      ++q s+   r +++++ ++++  +  a  g   
  gi|2125355   369 vdgySTQSSERSRDPSDDYQSSHYGQRvprgddygsGQYQQTRAAAGGYQ 418  

                   gppgpgvPGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsL
                        gv G+ P+ Dp kt ++iYPiLEFRDK+vR i  ++eKiPGLEsL
  gi|2125355   419 SSQPSGVSGL-PDIDPQKTVEQIYPILEFRDKVVRRISSIVEKIPGLESL 467  

                   lEkisEtLtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPW
                   ++ki Et+t F+ +LLAPF+RP+i+  sk+L+ Gs g+ie+s + q+E W
  gi|2125355   468 IDKITETVTLFVFSLLAPFIRPLINVASKSLQTGSMGVIESSGKHQYEVW 517  

                   nnPrCddPtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGv
                    +P+C+dPtHsmLsKDHF+n+Ln  AG vaa+i++YvvPR++ Awe    
  gi|2125355   518 DDPHCTDPTHSMLSKDHFANMLNQPAGQVAAAILKYVVPRVVHAWEHIDT 567  

                   PvdEvlnDiLrvFHHPAardEevEihrkmfetvkkWirEtknr.helnsl
                   Pvd v  D LrvFHHPAard + E h +mf+ v+ W++ + +r+h+ln l
  gi|2125355   568 PVDQVTHDCLRVFHHPAARDMHNEAHSTMFKAVESWVHSRSDRgHNLNDL 617  

                   LssEsvKeghnHvladqssdssrsvsagshtsnGadgGHGkvaGslWski
                   Ls+ sv++g+n  l ++    +     g+h+ +   gG   v+G l+   
  gi|2125355   618 LSAQSVRAGKN--LTKEAATTG-----GGHGHSHGGGGFPAVSGGLFGAG 660  

                   kkr<-*
                         
  gi|2125355   661 AAS    663  

gi|189189364|ref|XP_001931021.1|: domain 1 of 1, from 1 to 613: score 963.0, E = 1.4e-286
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         + +    +LLv+  +L+ LP  A AFGAGni si ++EG+nwRH
  gi|1891893     1    ---MGVSVNYMLLVAIAILVLLPAGADAFGAGNIASISKIEGQNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L tvA +kG+KW + m++RvYFGnWLRDYsq             
  gi|1891893    45 GDIEDMLATVACLKGHKWKSSMIKRVYFGNWLRDYSQ-----------GE 83   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vWvLsF++fGYAt EFEvt ERLG+YRPEEHiDn
  gi|1891893    84 TIRVL-----------VWVLSFMSFGYATGEFEVTAERLGCYRPEEHIDN 122  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                          +DARk+D+RLRGPv   EL +Dp++GmKnYiAnE+    gGW 
  gi|1891893   123 -------EDARKYDPRLRGPVSEAELAVDPETGMKNYIANER----GGW- 160  

                   atsAGYvrfslaRaiHFGRLYtsG.srgkGkEsDLCEALRCLGqALHclE
                   ats GYv++s+aRaiHFGRLYt G+s  +G+++DL EALRCLGq LHclE
  gi|1891893   161 ATSTGYVKYSFARAIHFGRLYTHGpSGQRGRDEDLSEALRCLGQGLHCLE 210  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nY EL+L+el     Gy +vFpH G +t inl      +Gk+ y
  gi|1891893   211 DFGAHTNYTELVLREL-----GYTNVFPHTGINTGINL------HGKHTY 249  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG+vDF HsvLGEA+DH tq+E+dE++ AL  A      +gG  
  gi|1891893   250 PLVTGTFGGVDFFHSVLGEANDHITQTEIDEVNTALVDA-----VAGG-- 292  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                     +RG         G + + +  i  +s++Pg Gd l  +A sL+A s+A
  gi|1891893   293 -NKRGGP------DGQSDACSGLIDALSKVPGTGD-LIRQAQSLQASSDA 334  

                   qEqqnsr......qltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   q  +n+r++ ++   +ra    f+appgs+ggppgp +PG   n Dp  +
  gi|1891893   335 QAAENARsgygdySSSRAGPESFDAPPGSVGGPPGPDIPGT--NTDPATI 382  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                     kiYPiL FRD +vRsi  +i+KiPGLE L+E i E +t F+L+LLAPF
  gi|1891893   383 IPKIYPILVFRDNVVRSISAIISKIPGLEKLIETITEKVTLFVLSLLAPF 432  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   + Pii+  s  LK Gss++i+++A+ q+E W +P  ++PtHsmLsKDHF+
  gi|1891893   433 ILPIIKTASAQLKSGSSAVIDSAAKHQYEVWTDPNSTNPTHSMLSKDHFA 482  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                   n+Ln  AG va++i+qYv PR++YAw+ P v vd vl D +rvFHHPA r
  gi|1891893   483 NILNQPAGQVAVAILQYVAPRVIYAWDHPDVSVDQVLDDCMRVFHHPATR 532  

                   dEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssd
                   d + E+h +mfe vk+W++   + ++ln lLssEsvK g+n ++a ++s 
  gi|1891893   533 DPNCEVHNNMFEVVKRWAHNY-HGKDLNDLLSSESVKSGRNQSGAHDHST 581  

                   ssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    +    a++ ++ G  + HG  +G   s+       
  gi|1891893   582 GH-GHGAAGVSAFGGGHSHGGSSGHAHSNSGGG    613  

gi|242793481|ref|XP_002482170.1|: domain 1 of 1, from 1 to 669: score 954.2, E = 5.7e-284
                   *->magLrigwg...svLLvlavvLivLPdkAAAFGAGniPsiAqvEGkn
                      ma     ++++++++ v  ++Li LP+kA AFGAGni si  vEGkn
  gi|2427934     1    MALGSFRSSpttAFVFVFLLMLIALPGKAEAFGAGNIASISTVEGKN 47   

                   wRHGDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   wRHGDiED+++ +AFi+G+KWt+ m++RvYFGnWLRDYsqA+DvG LK  
  gi|2427934    48 WRHGDIEDTIQALAFIHGHKWTSAMIKRVYFGNWLRDYSQAMDVGTLKNL 97   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A tiR++           vW+LsF++fGYAt EFEvt +RLGvYRPEEH
  gi|2427934    98 QADTIRVL-----------VWILSFMTFGYATGEFEVTADRLGVYRPEEH 136  

                   iDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqg
                   iDnPk+YAD++DAR++D RLR Pv   EL+iDp++GmKnYiAnE+    g
  gi|2427934   137 IDNPKDYADNQDARQYDKRLRPPVRQIELDIDPETGMKNYIANER----G 182  

                   GWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHc
                    W atsA Y+++s+ R+iH+GRLYtsG + kGkE+DL EALRCLGq LH+
  gi|2427934   183 DW-ATSAAYIKYSISRCIHYGRLYTSGGQSKGKEEDLFEALRCLGQGLHT 231  

                   lEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkr
                   lEDF+AHsnYCEL+L+e+     G+++vFpHvGa tei l      +Gkr
  gi|2427934   232 LEDFGAHSNYCELVLREM-----GFHNVFPHVGAATEIHL------RGKR 270  

                   vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgG
                   v+PLvtGtFG vDF HsvLGEA+DHFtqsE +E d  L++Ae +++s + 
  gi|2427934   271 VFPLVTGTFGMVDFFHSVLGEANDHFTQSELNEADNTLLGAESNQQSPAI 320  

                   GdsrqRGlllfglnlgGsgssgtDFisL.........vsqlPgvGdGlAs
                    ++    ll    ++ G      +   L+++++++ +  +   v  G+A 
  gi|2427934   321 -NT-LTSLL---GKIPGTKELVDEAEELqqrsnrqaeANRNRHVNTGYA- 364  

                   tARsL.........kAasaAqEqqnsrq.ltra........nvnvfnapp
                   t R +++ + ++ ++    A  +q s+ +++r++ ++ ++++  +   p 
  gi|2427934   365 TSRGVddypipsydQTRVPADHYQSSHYgQSRGpaggygsnEYDQSRGPS 414  

                   gstggppgpgvPGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPG
                             v G+ P+ Dp kt ++iYPiLEFRDK+vR i  ++eKiPG
  gi|2427934   415 DFQSNQQTSKVSGL-PDIDPQKTVEQIYPILEFRDKVVRRISSIVEKIPG 463  

                   LEsLlEkisEtLtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaq
                   LE L++ki Et+t F+ +LLAPF+RP+i+  sk+L+ Gs g+ie+s + q
  gi|2427934   464 LEKLIDKITETVTLFVFSLLAPFIRPLINVASKSLQTGSMGVIESSGQHQ 513  

                   lEPWnnPrCddPtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwe
                   +E W nP+C+dPtHsmLsKDHF+n+Ln  AG vaa+i+ YvvPR+lYAw+
  gi|2427934   514 YEVWDNPHCTDPTHSMLSKDHFANMLNEPAGQVAAAILRYVVPRVLYAWQ 563  

                   nPGvPvdEvlnDiLrvFHHPAardEevEihrkmfetvkkWirEtknr.he
                      v vd v  D L+vFHHPA rd + E h  mf+ v+ W++ +++r+h+
  gi|2427934   564 HIDVNVDQVTHDCLQVFHHPACRDMHNEAHTAMFKAVESWVQSRPDRgHN 613  

                   lnslLssEsvKeghnHvladqssdssrsvsagshtsnG..adgGHGkvaG
                   ln lLs+ sv++g+n   ++ s   +    + sh++ G +a  G    aG
  gi|2427934   614 LNDLLSAQSVRAGKNLTKNSSSTGGG---HGHSHGGGGfpAVSGGLYGAG 660  

                   slWskikkr<-*
                   +  s+ +++   
  gi|2427934   661 AASSHGQQQ    669  

gi|169608293|ref|XP_001797566.1|: domain 1 of 1, from 1 to 625: score 954.1, E = 6.2e-284
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m      +  +LLv+  +L+ LP +A AFGAGni si ++EG+nwRH
  gi|1696082     1    MG--VSSSQYLLLVAIAILVLLPTQAEAFGAGNIASISKIEGQNWRH 45   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED+L tvA +kG+KW + m++             AvDvG L  v+  
  gi|1696082    46 GDIEDMLATVACLKGHKWKSNMIK-------------AVDVGTLAKVQGE 82   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++           vWvLsF++fGYAt EFEvt ERLGvYRPEEHiDn
  gi|1696082    83 TIRVL-----------VWVLSFMSFGYATGEFEVTAERLGVYRPEEHIDN 121  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   Pk+YAD++DARk+D+RLRGPv   EL iDp++GmKnYiAnE+    gGW 
  gi|1696082   122 PKDYADNQDARKYDPRLRGPVSEAELAIDPHTGMKNYIANER----GGW- 166  

                   atsAGYvrfslaRaiHFGRLYtsGsrg.kGkEsDLCEALRCLGqALHclE
                   atsAGYv+fs+aRaiHFGRLYt G+ g++G+E+DL EALRCLGq LHclE
  gi|1696082   167 ATSAGYVKFSFARAIHFGRLYTHGASGqRGREEDLAEALRCLGQGLHCLE 216  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DF+AH+nY EL+L+el     Gy+dvFpHvG ++ i+l      nGkrvy
  gi|1696082   217 DFGAHTNYTELVLREL-----GYHDVFPHVGVEAGITL------NGKRVY 255  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   PLvtGtFG+vDF HsvLGEA+DH tqsE+dE++ AL  A   s    G  
  gi|1696082   256 PLVTGTFGGVDFFHSVLGEANDHITQSEIDEVNTALVDA--VSSNTTG-- 301  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                     +RG         G + + +  + ++s++Pg Gd l  +A +L+A s+A
  gi|1696082   302 --KRGPG-------GEAPACSGLVDVLSKVPGTGD-LIRQAQDLQASSDA 341  

                   qEqqnsr......qltranvnv......fnappgstggppgpgvPGmsPn
                   q   n+r+++ ++  tra +  + ++++f+appgs+ggppgp +PG   +
  gi|1696082   342 QAASNARsggyddYSTRAGGQGgyqqsgFDAPPGSVGGPPGPNIPGT--D 389  

                   FDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiL
                    Dp  +  kiYPiL FRD +vRsi  +++KiPGLE L+E i E +t F+L
  gi|1696082   390 TDPATIIPKIYPILVFRDNVVRSISAIVSKIPGLEKLIETITERVTLFVL 439  

                   gLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmL
                   +LLAPF+ Pii+  s  LK Gss++i+++A+ q+E W  P   dPtHsmL
  gi|1696082   440 SLLAPFILPIIKTASSQLKSGSSAVIDSAAKHQYEVWTIPTSSDPTHSML 489  

                   sKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvF
                   sKDHF+nvLn  AG va++i+qYv PR++YAw+ P vPvd vl D +rvF
  gi|1696082   490 SKDHFSNVLNQPAGQVAVAILQYVAPRVIYAWDHPDVPVDQVLDDCMRVF 539  

                   HHPAardEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvl
                   HHP  rd++ Eihr+mfe vkkW++   + ++ln +LssEsv++g+    
  gi|1696082   540 HHPGMRDDRCEIHRNMFEVVKKWAHNY-RGKDLNYVLSSESVRAGQEPQR 588  

                   adqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    ++s  +    +    +s         +a ++ +   +    
  gi|1696082   589 LKRSLTRR--SPMEQQASRALAVHQADTAAAVTEAAATN    625  

gi|226286434|gb|EEH42000.1|: domain 1 of 1, from 165 to 778: score 906.3, E = 1.6e-269
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s +L+lav+L+ LP++  AFGAGni si  +EGknwRH
  gi|2262864   165    TFNMGLGARSSILILAVLLVLLPSQVCAFGAGNIASISTIEGKNWRH 211  

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++Kt+AF+kG+KWt +m++R YFGnWLRDYsqAvDvG +  ++A 
  gi|2262864   212 GDIEDTIKTLAFLKGHKWTGIMIKRLYFGNWLRDYSQAVDVGTVSKIQAD 261  

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsF afGYAt EFEvt ERL vYRPEEHiD 
  gi|2262864   262 TIRIL-----------VWILSFGAFGYATGEFEVTAERLCVYRPEEHID- 299  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                                D+RLRGP+ P ELEiDp+sGmKnYiAnE+    g W 
  gi|2262864   300 -------------DPRLRGPIRPIELEIDPQSGMKNYIANER----GDW- 331  

                   atsAGYvrfslaRaiHFGRLYtsGsrg.kGkEsDLCEALRCLGqALHclE
                   atsAGYv++s+aR+iHFGRLY +G r++kG+E+ L EALRCLGqA H+lE
  gi|2262864   332 ATSAGYVKYSVARSIHFGRLYLAGGRHeKGREEHLSEALRCLGQACHTLE 381  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCELaL+e+      y +vFpH G  t++n+      +Gk v+
  gi|2262864   382 DFSAHSNYCELALREM-----NYTNVFPHTGVGTQMNI------QGKYVF 420  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG  DF Hs LGEA D F qsEv+Emd  L++A+  s ssg  +
  gi|2262864   421 PVVTGTFGMTDFFHSLLGEASDQFAQSEVNEMDNTLGTAQSGSGSSGALS 470  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                   s    l                  sL+s++Pg+ +G+  +A  Lk +s+A
  gi|2262864   471 S----LT-----------------SLLSKVPGM-NGMIEEAERLKRKSEA 498  

                   qEqqnsrq......ltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   qEq n +++ ++ + tr++             p   g    s +  p +t
  gi|2262864   499 QEQSNQQRgldgygATRGQFDH--QGIERYNQPTEYGQSQASQEINPQET 546  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                     ++YPiLEFRD++v+ +   +eKiPGL sL++kisEtL +Fi +LLAPF
  gi|2262864   547 IFQVYPILEFRDRVVKNLSSAVEKIPGLSSLMDKISETLSIFIFSLLAPF 596  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   +RP+i+  s  L+ Gss l +a A+ q+EPW nP C+dPtHs LsKDHF+
  gi|2262864   597 IRPVIKIASAKLQLGSSELTAAEARTQYEPWTNPNCTDPTHSFLSKDHFS 646  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                   n+Ln  AGRva+++v++vvPR+lYA++   vPvd vlnD + +FHHPA r
  gi|2262864   647 NILNDPAGRVASAVVKFVVPRVLYAFQHVDVPVDRVLNDCVSIFHHPAFR 696  

                   dEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqss
                       E hr+mf  v++W++ +  ++ +ln +Ls+EsvK+g+nH + + + 
  gi|2262864   697 RFDNEAHRNMFAEVERWAHSQSSKgVNLNNVLSAESVKAGKNHTGGNPHT 746  

                   d.ssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   ++ ++s +a+sh  +    GH    G   s+  +    
  gi|2262864   747 HgTGHSHAAPSHNQT---YGHSNSQGHNHSQPGHG    778  

gi|261204825|ref|XP_002629626.1|: domain 1 of 1, from 1 to 607: score 864.9, E = 4.6e-257
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s++ +la++L+ LP++  AFGAGni si  vEGknwRH
  gi|2612048     1    ---MGLGTRSIIFILAILLVLLPSQVHAFGAGNIASISVVEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDi D++Kt+AFikG+KWt +m++R YFGnWLRDYsqA+DvG +  ++A 
  gi|2612048    45 GDIQDIVKTLAFIKGHKWTGIMMKRLYFGNWLRDYSQAIDVGTVSKIQAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                    iR++           vW+LsF+afGYAt+EFEvt ERLGvYRPEEHiDn
  gi|2612048    95 SIRVL-----------VWILSFMAFGYATAEFEVTAERLGVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgY D kDAR++D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2612048   134 PKGYSDDKDARQYDPRLRGPIRPIELEIDPETGMKNYIANER----GDW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYvr+s+aR+iHFGRLY                   LG ALH+lED
  gi|2612048   179 ATSAGYVRYSIARSIHFGRLY-------------------LG-ALHTLED 208  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCEL+L+e+      y++vFpHvG  t++n+      +Gk ++P
  gi|2612048   209 FSAHSNYCELVLREM-----NYHNVFPHVGVATQMNI------QGKYIFP 247  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   +vtGtFG  DF Hs LG A D   qsE++Emd  L++A+  s ssg    
  gi|2612048   248 IVTGTFGMTDFFHSLLGGASDNLAQSEINEMDNTLGSAQTGSGSSGA--- 294  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l+                 sL+s++Pg+  Gl  +A  Lk +s+Aq
  gi|2612048   295 ----LS--------------ALTSLLSKVPGM-KGLIEEAEALKRKSEAQ 325  

                   Eqqnsrq..ltranvnvfnappgstg..gppgpgvPGms..PnFDpvkta
                    q n +++    a       p g  g +   +   P  s++ +  p +t 
  gi|2612048   326 AQANQHRglDDYAASRSHFDPHGNQGlnQHSAYNQPRAStpADINPQETI 375  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                    +iYPiLEFRD++ + +    eKiPGL sL+EkisEtL +Fi +LLAPF+
  gi|2612048   376 SQIYPILEFRDRVAKRLSAAFEKIPGLASLMEKISETLSIFIFSLLAPFI 425  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                   RP+i+  s  L+ G+  l ++ A+aq+EPW nP C+dPtHs LsKDHF+n
  gi|2612048   426 RPVIKIASSKLQLGADELKASEAQAQFEPWTNPACTDPTHSFLSKDHFSN 475  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAard
                   +Ln  AGRva+++v++vvPR++YA++   vPvd vl D + v HHPA+r 
  gi|2612048   476 ILNDPAGRVASAVVKFVVPRVIYAFQHVDVPVDQVLDDCVSVLHHPALRR 525  

                   EevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqssd
                      E h++mf  v++W+rE+ +++ +ln +Ls++ vK+g+nHv+ d + +
  gi|2612048   526 SDNEAHQEMFAEVERWAREKARKgIDLNDILSADGVKAGKNHVGGDPHAH 575  

                   ssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    +    + +h    +++     a s  s+ +++   
  gi|2612048   576 THGNSNTHAHVPPPSQHQSYGYAPS-HSHNHSQ    607  

gi|239614043|gb|EEQ91030.1|: domain 1 of 1, from 1 to 607: score 864.9, E = 4.6e-257
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s++ +la++L+ LP++  AFGAGni si  vEGknwRH
  gi|2396140     1    ---MGLGTRSIIFILAILLVLLPSQVHAFGAGNIASISVVEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDi D++Kt+AFikG+KWt +m++R YFGnWLRDYsqA+DvG +  ++A 
  gi|2396140    45 GDIQDIVKTLAFIKGHKWTGIMMKRLYFGNWLRDYSQAIDVGTVSKIQAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                    iR++           vW+LsF+afGYAt+EFEvt ERLGvYRPEEHiDn
  gi|2396140    95 SIRVL-----------VWILSFMAFGYATAEFEVTAERLGVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgY D kDAR++D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2396140   134 PKGYSDDKDARQYDPRLRGPIRPIELEIDPETGMKNYIANER----GDW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                   atsAGYvr+s+aR+iHFGRLY                   LG ALH+lED
  gi|2396140   179 ATSAGYVRYSIARSIHFGRLY-------------------LG-ALHTLED 208  

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                   FsAHsnYCEL+L+e+      y++vFpHvG  t++n+      +Gk ++P
  gi|2396140   209 FSAHSNYCELVLREM-----NYHNVFPHVGVATQMNI------QGKYIFP 247  

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                   +vtGtFG  DF Hs LG A D   qsE++Emd  L++A+  s ssg    
  gi|2396140   248 IVTGTFGMTDFFHSLLGGASDNLAQSEINEMDNTLGSAQTGSGSSGA--- 294  

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                       l+                 sL+s++Pg+  Gl  +A  Lk +s+Aq
  gi|2396140   295 ----LS--------------ALTSLLSKVPGM-KGLIEEAEALKRKSEAQ 325  

                   Eqqnsrq..ltranvnvfnappgstg..gppgpgvPGms..PnFDpvkta
                    q n +++    a       p g  g +   +   P  s++ +  p +t 
  gi|2396140   326 AQANQHRglDDYAASRSHFDPHGNQGlnQHSAYNQPRAStpADINPQETI 375  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                    +iYPiLEFRD++ + +    eKiPGL sL+EkisEtL +Fi +LLAPF+
  gi|2396140   376 SQIYPILEFRDRVAKRLSAAFEKIPGLASLMEKISETLSIFIFSLLAPFI 425  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                   RP+i+  s  L+ G+  l ++ A+aq+EPW nP C+dPtHs LsKDHF+n
  gi|2396140   426 RPVIKIASSKLQLGADELKASEAQAQFEPWTNPACTDPTHSFLSKDHFSN 475  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAard
                   +Ln  AGRva+++v++vvPR++YA++   vPvd vl D + v HHPA+r 
  gi|2396140   476 ILNDPAGRVASAVVKFVVPRVIYAFQHVDVPVDQVLDDCVSVLHHPALRR 525  

                   EevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqssd
                      E h++mf  v++W+rE+ +++ +ln +Ls++ vK+g+nHv+ d + +
  gi|2396140   526 SDNEAHQEMFAEVERWAREKARKgIDLNDILSADGVKAGKNHVGGDPHAH 575  

                   ssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    +    + +h    +++     a s  s+ +++   
  gi|2396140   576 THGNSNTHAHVPPPSQHQSYGYAPS-HSHNHSQ    607  

gi|226291888|gb|EEH47316.1|: domain 1 of 1, from 1 to 594: score 832.1, E = 3.3e-247
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s +L+lav+L+ LP++  AFGAGni si  +EGknwRH
  gi|2262918     1    ---MGLGTRSSILILAVLLVLLPSQVCAFGAGNIASISTIEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++Kt+AFikG+KWt +m++R YFGnWLRDYsqAvDvG +  ++A 
  gi|2262918    45 GDIEDTIKTLAFIKGHKWTGIMIKRLYFGNWLRDYSQAVDVGTVSKIQAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsF afGYAt EFEvt ERL vYRPEEHiD 
  gi|2262918    95 TIRIL-----------VWILSFGAFGYATGEFEVTAERLCVYRPEEHID- 132  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                                D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2262918   133 -------------DPRLRGPIRPIELEIDPQTGMKNYIANER----GDW- 164  

                   atsAGYvrfslaRaiHFGRLYtsGsrg.kGkEsDLCEALRCLGqALHclE
                   atsAGYvr+s+aR+iHFGRLY +G r++kG+E+ L EALRCLGqA H+lE
  gi|2262918   165 ATSAGYVRYSVARSIHFGRLYLAGGRHeKGREEHLSEALRCLGQACHTLE 214  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCELaL+e+      y +vFpH G  t++n+      + k v+
  gi|2262918   215 DFSAHSNYCELALREM-----NYTNVFPHTGVGTQMNI------QEKYVF 253  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgG..
                   P+vtGtFG  DF Hs LGEA D F qsE  E    ++ Ae++++ s  + 
  gi|2262918   254 PVVTGTFGMTDFYHSLLGEASDQFAQSESPEWSGMIEEAERLKRKSEAqa 303  

                   GdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAas
                    + +qRGl        G g+s + F                         
  gi|2262918   304 QSNQQRGLD-------GYGASRGQF------------------------- 321  

                   aAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakki
                      ++q  +       n+          p g g      +  p +t  +i
  gi|2262918   322 ---DHQGIE-----PYNQ----------PTGYGQSQATQEINPQETIFQI 353  

                   YPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPi
                   YPiLEFRD++v+ +   +eKiPGL sL++kisEtL +Fi +LLAPF+RP+
  gi|2262918   354 YPILEFRDRVVKNLSSAVEKIPGLSSLMDKISETLSIFIFSLLAPFIRPV 403  

                   idqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLn
                   i+  s  L+ Gss l +a A+ q+EPW nP C+dPtHs LsKDHF+n+Ln
  gi|2262918   404 INIASAKLQLGSSELTAAEARTQYEPWTNPNCTDPTHSFLSKDHFSNILN 453  

                   sCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEev
                     AGRva+++v++vvPR+lYA++   vPvd vlnD + vFHHPA r    
  gi|2262918   454 DPAGRVASAVVKFVVPRVLYAFQHVDVPVDRVLNDCVSVFHHPAFRRFDN 503  

                   EihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqssd.ss
                   E hr+mf  v++W++ +  ++ +ln +Ls+EsvK+g+nH + + + ++ +
  gi|2262918   504 EAHRNMFAEVERWAHSQSSKgINLNNVLSAESVKAGKNHTGGNPHAHgTG 553  

                   rsvsagsh..........tsnGadgGHGkvaGslWskikkr<-*
                    + +a+sh+++ +++++++ n ++ GHG+      ++ +++   
  gi|2262918   554 NAHAAPSHnqtyghsnspSHNHSQPGHGHSNYGGHNQFQSH    594  

gi|154286346|ref|XP_001543968.1|: domain 1 of 1, from 1 to 612: score 791.0, E = 7.8e-235
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g   ++ +la++L+ LP++  AFGAGni si  vEG+nwRH
  gi|1542863     1    ---MGSGTTFAIFILAILLVLLPSQVHAFGAGNIASISVVEGRNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++K +AFikG+KWt +m++R YFGnW         v  L   +  
  gi|1542863    45 GDIEDTVKALAFIKGHKWTGIMIKRLYFGNW---------VERLLPSSRC 85   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                      i+              Ls   fG+       t            + n
  gi|1542863    86 GNHIV---------NPSRKLSGSWFGFSASPLSDTQPL--------NLSN 118  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD+kDAR++D+RLR P+ P ELEiDp++GmKnYiAnE+    g W 
  gi|1542863   119 PKGYADNKDARQYDPRLRAPIRPIELEIDPQTGMKNYIANER----GDW- 163  

                   atsAGYvrfslaRaiHFGRLYt.sGsrgkGkEsDLCEALRCLGqALHclE
                   atsAG+v++s+aR+iHFGRLY + Gs++kG+E+ L EALRCLGqA H+lE
  gi|1542863   164 ATSAGFVKYSIARSIHFGRLYLgGGSHEKGREEHLSEALRCLGQACHTLE 213  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCEL+L+e+     Gy++vFpHvG  t++n+      +Gk v+
  gi|1542863   214 DFSAHSNYCELVLREM-----GYHNVFPHVGVGTQMNI------QGKYVF 252  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG  DF Hs LGEA D  tqsE++Emd AL++A+  s ssg   
  gi|1542863   253 PIVTGTFGMTDFFHSLLGEASDNLTQSEINEMDNALGSAQAGSGSSGA-- 300  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                        l+                 +++s++Pg+  G+ ++A  Lk +s+A
  gi|1542863   301 -----LS--------------ALTGVLSKVPGM-KGFIAEAEALKRKSEA 330  

                   qEqqnsrqltranvnv..fnappgstg....gppgpgvPGmsPnFDpvkt
                   q q n ++   + +  ++   p g  g +++ p g     +  +  p +t
  gi|1542863   331 QAQANQQRGFGDYGASrsHSDPHGNQGlnqpIPYGQSRASVPTDINPQET 380  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                     +iYPiLEFRD++vR i   +eKiPGL sL+Eki EtL +Fi +LLAPF
  gi|1542863   381 ISQIYPILEFRDRVVRNISSALEKIPGLASLMEKIGETLSIFIFSLLAPF 430  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   +RP+i+  s  L+ Gss l ++ A+ q+EPW nP C+dPtHs LsKDHF+
  gi|1542863   431 IRPVIKVASSNLQLGSSELTASEARVQFEPWTNPACTDPTHSFLSKDHFS 480  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                   n+Ln  AGRvaa++v++vvPR+lYA++   vPvd vlnD + vFHHPA r
  gi|1542863   481 NILNDPAGRVAAAVVKFVVPRVLYAFQHVDVPVDLVLNDCVLVFHHPAFR 530  

                   dEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqss
                       E+hr+mf  v++W++E+ +++ ++n++Ls+E vK+g+nH++ d + 
  gi|1542863   531 RSDNEVHREMFAEVERWAHEKSRKgFNFNHILSAEGVKAGKNHIGGDPHA 580  

                   dssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + +    + +h+s      HG++  s  +   +    
  gi|1542863   581 HAH--GNSNTHASPSQHQTHGHTLPSQHQPYGHA    612  

gi|240274951|gb|EER38466.1|: domain 1 of 1, from 1 to 570: score 756.8, E = 1.6e-224
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s+L +la++L+ LP++  AFGAGni si  vEG+nwRH
  gi|2402749     1    ---MGSGTTSALFILAILLVLLPSQVHAFGAGNIASISVVEGRNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++K +AFikG+KWt +m++R YFGn                    
  gi|2402749    45 GDIEDTVKALAFIKGHKWTGIMIKRLYFGN-------------------- 74   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                                                                    n
  gi|2402749    75 ----C--------------------------------------------N 76   

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD+kDAR++D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2402749    77 PKGYADNKDARQYDPRLRGPIRPIELEIDPQTGMKNYIANER----GDW- 121  

                   atsAGYvrfslaRaiHFGRLYt.sGsrgkGkEsDLCEALRCLGqALHclE
                   atsAG+v++s+aR+iHFGRLY + Gs++kG+E+ L EALRCLGqA H+lE
  gi|2402749   122 ATSAGFVKYSIARSIHFGRLYLgGGSHEKGREEHLSEALRCLGQACHTLE 171  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCEL+L+e+     Gy++vFpHvG  t++n+      +Gk v+
  gi|2402749   172 DFSAHSNYCELVLREM-----GYHNVFPHVGVGTQMNI------QGKYVF 210  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG  DF Hs LGEA D  tqsE++Emd  L++A+  s ssg   
  gi|2402749   211 PIVTGTFGMTDFFHSLLGEASDNLTQSEINEMDNTLGSAQAGSGSSGA-- 258  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                        l+                 +++s++Pg+  G+ ++A  Lk +s+A
  gi|2402749   259 -----LS--------------ALTGVLSKVPGM-KGFIAEAEALKRKSEA 288  

                   qEqqnsrqltranvnv..fnappgstg....gppgpgvPGmsPnFDpvkt
                   q q n ++   + +  ++   p g  g +++ p g     +  +  p +t
  gi|2402749   289 QAQANQQRGFGDYGASrsHSDPHGNQGlnqpIPYGQSRASVPTDINPQET 338  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                     +iYPiLEFRD++vR i   +eKiPGL sL+Eki EtL +Fi +LLAPF
  gi|2402749   339 VSQIYPILEFRDRVVRNISSAVEKIPGLSSLMEKIGETLSIFIFSLLAPF 388  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   +RP+i+  s  L+ Gss l ++ A+ q+EPW nP C+dPtHs LsKDHF+
  gi|2402749   389 IRPVIKVASSNLQLGSSELTASEARVQFEPWTNPACTDPTHSFLSKDHFS 438  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                   n+Ln  AGRvaa++v++vvPR+lYA++   vPvd vlnD + vFHHPA+r
  gi|2402749   439 NILNDPAGRVAAAVVKFVVPRVLYAFQHVDVPVDLVLNDCVLVFHHPALR 488  

                   dEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqss
                       Eihr+mf  v++W++E+ +++ ++n +Ls+E vK+g+nH++ d + 
  gi|2402749   489 RSDNEIHREMFAEVERWVHEKSRKgFNFNDILSAEGVKAGKNHIGGDPHA 538  

                   dssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + +    + +h+s      HG++  s  +   +    
  gi|2402749   539 HAH--GNSNTHASPSQHQTHGHTLPSQHQPYGHA    570  

gi|225558518|gb|EEH06802.1|: domain 1 of 1, from 1 to 570: score 752.8, E = 2.5e-223
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s+L +la++L+ LP++  AFGAGni si  vEG+nwRH
  gi|2255585     1    ---MGSGTTSALFILAILLVLLPSQVHAFGAGNIASISVVEGRNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++K +AFikG+KWt +m++R YFGn                    
  gi|2255585    45 GDIEDTVKALAFIKGHKWTGIMIKRLYFGN-------------------- 74   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                                                                    n
  gi|2255585    75 ----C--------------------------------------------N 76   

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD+kDAR++D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2255585    77 PKGYADNKDARQYDPRLRGPIRPIELEIDPQTGMKNYIANER----GDW- 121  

                   atsAGYvrfslaRaiHFGRLYt.sGsrgkGkEsDLCEALRCLGqALHclE
                   atsAG+v++s+aR+iHFGRLY + Gs++kG+E+ L EALRCLGqA H+lE
  gi|2255585   122 ATSAGFVKYSIARSIHFGRLYLgGGSHEKGHEEHLSEALRCLGQACHTLE 171  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCEL+L+e+     Gy++vFpHvG  t++n+      +Gk v+
  gi|2255585   172 DFSAHSNYCELVLREM-----GYHNVFPHVGVGTQMNI------QGKYVF 210  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG  DF Hs LGEA D  tqsE++Emd  L++A+  s ssg   
  gi|2255585   211 PIVTGTFGMTDFFHSLLGEASDNLTQSEINEMDNTLGSAQAGSGSSGA-- 258  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                        l+                 +++s++Pg+  G+ ++A  Lk +s+A
  gi|2255585   259 -----LS--------------ALTGVLSKVPGM-KGFIAEAEALKRKSEA 288  

                   qEqqnsrqltranvnv..fnappgstg....gppgpgvPGmsPnFDpvkt
                   q q n ++   + +  ++   p g  g +++ p g     +  +  p +t
  gi|2255585   289 QAQANQQRGFGDYGASrsHSDPHGNQGlnqpIPYGQSRASVPTDINPQET 338  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                     +iYPiLEFRD++vR i   +eKiPGL sL+EkisEtL +Fi +LLAPF
  gi|2255585   339 ISQIYPILEFRDRVVRNISSALEKIPGLASLMEKISETLSIFIFSLLAPF 388  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   +RP+i+  s  L+ Gss l ++ A+ q+EPW nP C+dPtHs LsKDHF+
  gi|2255585   389 IRPVIKVASSNLQLGSSELTASEARVQFEPWTNPACTDPTHSFLSKDHFS 438  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                   n+Ln  AGRvaa++v++vvPR+lYA++   vPvd vlnD + vFHHPA r
  gi|2255585   439 NILNDPAGRVAAAVVKFVVPRVLYAFQHVDVPVDLVLNDCVLVFHHPAFR 488  

                   dEevEihrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqss
                       E+hr+mf  v++W++E+ +++ ++n +Ls+E vK+g+nH++ d + 
  gi|2255585   489 RSDNEVHREMFAEVERWAHEKSRKgVNFNDILSAEGVKAGKNHIGGDPHA 538  

                   dssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + +    + +h+s      HG++  s  +   +    
  gi|2255585   539 HAH--GNSNTHASPSQHQTHGHTLPSQHQPYGHA    570  

gi|225680092|gb|EEH18376.1|: domain 1 of 1, from 1 to 504: score 669.9, E = 2.3e-198
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +  g  s +L+lav+L+ LP++  AFGAGni si  +EGknwRH
  gi|2256800     1    ---MGLGTRSSILILAVLLVLLPSQVCAFGAGNIASISTIEGKNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED++Kt+AFikG+KWt +m++R YFGnWLRDYsqAvDvG +  ++A 
  gi|2256800    45 GDIEDTIKTLAFIKGHKWTGIMIKRLYFGNWLRDYSQAVDVGTVSKIQAD 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiRi+           vW+LsF afGYAt EFEvt ERL vYRPEEHiDn
  gi|2256800    95 TIRIL-----------VWILSFGAFGYATGEFEVTAERLCVYRPEEHIDN 133  

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                   PkgYAD+kDAR++D+RLRGP+ P ELEiDp++GmKnYiAnE+    g W 
  gi|2256800   134 PKGYADGKDARQYDPRLRGPIRPIELEIDPQTGMKNYIANER----GDW- 178  

                   atsAGYvrfslaRaiHFGRLYtsGsrg.kGkEsDLCEALRCLGqALHclE
                   atsAGYvr+s+aR+iHFGRLY +G r++kG+E+ L EALRCLGqA H+lE
  gi|2256800   179 ATSAGYVRYSVARSIHFGRLYLAGGRHeKGREEHLSEALRCLGQACHTLE 228  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   DFsAHsnYCELaL+e+      y +vFpH G  t++n+      + k v+
  gi|2256800   229 DFSAHSNYCELALREM-----NYTNVFPHTGVGTQMNI------QEKYVF 267  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG  DF Hs LGEA D F qsE                      
  gi|2256800   268 PVVTGTFGMTDFYHSLLGEASDQFAQSE---------------------- 295  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                      R l+                                           
  gi|2256800   296 ---RNLS------------------------------------------- 299  

                   qEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYP
                                                                     
  gi|2256800     - -------------------------------------------------- -    

                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiid
                                                     +Fi +LLAPF+RP+i+
  gi|2256800   300 ----------------------------------IFIFSLLAPFIRPVIN 315  

                   qvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsC
                     s  L+ Gss l +a A+ q+EPW nP C+dPtHs LsKDHF+n+Ln  
  gi|2256800   316 IASAKLQLGSSELTAAEARTQYEPWTNPNCTDPTHSFLSKDHFSNILNDP 365  

                   AGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEi
                   AGRva+++v++vvPR+lYA++   vPvd vlnD + vFHHPA r    E 
  gi|2256800   366 AGRVASAVVKFVVPRVLYAFQHVDVPVDRVLNDCVSVFHHPAFRRFDNEA 415  

                   hrkmfetvkkWirEtknr.helnslLssEsvKeghnHvladqssd.ssrs
                   hr+mf  v++W++ +  ++ +ln +Ls+EsvK+g+nH + + + ++ + +
  gi|2256800   416 HRNMFAEVERWAHSQSSKgINLNNVLSAESVKAGKNHTGGNPHAHgTGNA 465  

                   vsagsh..........tsnGadgGHGkvaGslWskikkr<-*
                    +a+sh+++ +++++++ n ++ GHG+      ++ +++   
  gi|2256800   466 HAAPSHnqtyghsnspSHNHSQPGHGHSNYGGHNQFQSH    504  

gi|115385404|ref|XP_001209249.1|: domain 1 of 1, from 1 to 607: score 652.2, E = 4.8e-193
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m   ++ w+ +L    v L    ++A AFGAGni si +vEG+nwRH
  gi|1153854     1    MGLSIPSWAIFL----VALFAFSGQAHAFGAGNIASISRVEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED+L t+   +  +G+K+  + v+RvYFGnWLRDYsqAvDvG LK v
  gi|1153854    44 GDIEDTLLTLVLARvagGRKFSKLDVQRVYFGNWLRDYSQAVDVGTLKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +   iRi+           +WvL Fl+fGY t+EFEvt ERLG+Y P EH
  gi|1153854    94 STEAIRIL-----------IWVLGFLSFGYGTKEFEVTTERLGCYEPTEH 132  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYA+++DARk+D RLRGP+d+ rEL i pr+G+KnYiA E     
  gi|1153854   133 IDNPLGYAEGEDARKYDRRLRGPIDeERELSINPRTGLKNYIASEN---- 178  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G  +tsA  vr  + R+i  GR Y       G  +DL EALR LG  LH
  gi|1153854   179 LGI-STSAALVRRVFRRSIQLGREYG----RSGNKEDLHEALRLLGTGLH 223  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Liel     G ++vFpHvG dt+i l       Gk
  gi|1153854   224 CLEDYAAHSNYTELSLIEL-----GESEVFPHVGRDTKIDL------DGK 262  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDF HsvLGE  D  tqsE++ ++  +   e      +
  gi|1153854   263 DVYPIVTGTFGGVDFFHSVLGELSDKATQSEIQSLEGVISESENDGAPDS 312  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                        q  l+ +   l Gs+s++                 A +  + kA+
  gi|1153854   313 L---LQDLLSKIPEGLIGSSSDEE----------------ADKMNDFKAQ 343  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   s+   q+n +   r+                           D v   ++
  gi|1153854   344 SQNAKQHNQNISPREPEEW-------------------TRYLDEVH--QQ 372  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   i P+LE+ D +++sin  ieKiP +  L+E+i E + +F+ +++AP+v P
  gi|1153854   373 ILPVLEWHDNLIKSINEAIEKIPVIPDLIEQIQEQINVFVFSIIAPYVLP 422  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qv   L+ Gss +i++s ++q   + n  C dPtHsmLsKDHF+nvL
  gi|1153854   423 IIQQVKTELQTGSSEVIQSSREQQHVVFDNDSCSDPTHSMLSKDHFSNVL 472  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAardE
                   n  AGRva+ iv++vvP ++  w+n    +   l  i+++vFHHPA+rd 
  gi|1153854   473 NEPAGRVASQIVKWVVPQLMECWDNEDADIKRTLDRIVHgVFHHPALRDR 522  

                   ....evEihrkmfetvkkWirEtknrhelnsl...LssEsvKeghnHvla
                   ++++  Ei++ mf tv++W +++ +r e ++l+++Ls E v+eg+nH   
  gi|1153854   523 gedgADEIRQIMFGTVQQWWEDK-DRDEQDTLreqLSREGVQEGKNHKEG 571  

                   dqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    q   ++     +     G     G++ G   ski+k    
  gi|1153854   572 VQDCGHG--CGKPLTLHKGQARTSGRTGGPDTSKIEKI    607  

gi|169621851|ref|XP_001804335.1|: domain 1 of 1, from 1 to 600: score 643.3, E = 2.4e-190
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+  r + +s+ L   v+L+    + AAFGAGni s+  vEG+nwRH
  gi|1696218     1    MSS-RLELSSFWLPCLVLLVFWARPTAAFGAGNIASLSSVEGQNWRH 46   

                   GDiEDvLKtvAF..ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvn
                   GDiED+L t+  ++  GkK+  m v+RvYFGnWLRDYsqAvDvG +K v+
  gi|1696218    47 GDIEDTLLTLLIssRTGKKFSKMDVKRVYFGNWLRDYSQAVDVGTVKMVS 96   

                   AatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHi
                   A  iRi+            WvL F++fGY t+EFEvt +RLG+YRPEEHi
  gi|1696218    97 AEAIRIL-----------LWVLGFMSFGYGTKEFEVTRDRLGCYRPEEHI 135  

                   DnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEslayqg
                   DnPk+YAD+ DAR++D RLR Pvd +rEL +D r+G+KnYiA E      
  gi|1696218   136 DNPKDYADNLDAREYDRRLRAPVDErRELSVDERTGLKNYIASED----L 181  

                   GWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHc
                   G  +tsAG vr  l R+i  GR      r  G+  D  EALR LG A Hc
  gi|1696218   182 GI-TTSAGMVRDLLRRCIDLGR------RSGGRGPDFHEALRLLGTATHC 224  

                   lEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkr
                   lED+sAHsnY EL+Liel     G rd+FpHvG +++ ++    +   k+
  gi|1696218   225 LEDYSAHSNYTELVLIEL-----GERDIFPHVGRNAQFEI----QAARKQ 265  

                   vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgG
                   vyP++tGtFG+vDFLHsv GE  D  tqsE +E++ A+  A+++++ s  
  gi|1696218   266 VYPIITGTFGGVDFLHSVCGELSDKATQSELQELEGAISDADRKKNKSQI 315  

                   GdsrqRGlllfglnlgGsgssgtDFisLvsqlP.gv..GdGlAstARsLk
                                              L+sqlP+g+ +G     +A +L+
  gi|1696218   316 -------------------------KDLLSQLPdGIfgGKDQGGKADELE 340  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                     + A    n++  t ++   f    g                    +  
  gi|1696218   341 NNASAAAMGNMH-VTPKEPEAFTEQLG--------------------ELV 369  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   k+iYPi+EF D i+ si   ieKiP L  ++E++ E +t+F+ +LLAP+v
  gi|1696218   370 KQIYPIMEFHDEIMMSISEFIEKIPILPEIIEQVQEQVTVFVFSLLAPYV 419  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    Pii qv   L  Gss +i++s ++q   +n+   +dPtHsmLsKDHF+n
  gi|1696218   420 LPIISQVKAELETGSSEVIASSREKQHIVFNDDYSTDPTHSMLSKDHFSN 469  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAard
                   +Ln  AGRva++++ + vP i+  w+  G P + +   i  vFHHPA  +
  gi|1696218   470 ILNEPAGRVASAVLTWAVPQIVQCWDGQGDPEETISRIIDGVFHHPAVPQ 519  

                   Eev....EihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladq
                    +v++++  +  mf+tv+kW r ++++ +l+  Ls   v++g nH   + 
  gi|1696218   520 GRVrgseQCRSIMFQTVEKWWRAQPDQDDLRRKLSRRGVQNGENH-KPGM 568  

                   ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +++ +    + +     a+   G v Gs  ++  ++   
  gi|1696218   569 HDKGH----GCGKPLGMANDFSGIVGGSGGNRQAQQ    600  

gi|189196973|ref|XP_001934824.1|: domain 1 of 1, from 1 to 602: score 637.8, E = 1e-188
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                          ++  + + L   ++L+    + AAFGAGni s+  +EG+nwRH
  gi|1891969     1    ----MPQISDIWLPCLILLVFWTRPTAAFGAGNIASLSSIEGQNWRH 43   

                   GDiEDvLKtvAF..ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvn
                   GDiED+L t+  ++  GkK+  m v+RvYFGnWLRDYsqAvDvG +K v+
  gi|1891969    44 GDIEDTLLTLLIsgQTGKKFSKMDVKRVYFGNWLRDYSQAVDVGTVKMVS 93   

                   AatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHi
                   A  iRi+            WvL F++fGY t EFEvt +RLG+YRPEEHi
  gi|1891969    94 AEAIRIL-----------LWVLGFMSFGYGTGEFEVTRDRLGCYRPEEHI 132  

                   DnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEslayqg
                   DnPk+YAD+ DAR++D RLR Pvd +rEL iD r+G+KnYiA E      
  gi|1891969   133 DNPKDYADNIDARDYDRRLRAPVDErRELSIDERTGLKNYIASEN----V 178  

                   GWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHc
                   G  +tsAG vr  l R+i  G       r  G+  D  EALR LG A Hc
  gi|1891969   179 GI-TTSAGMVRDLLRRCIDLGQ------RSGGRGPDFYEALRLLGTATHC 221  

                   lEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkr
                   lED+sAHsnY ELaLie+     G +d+FpHvG +++  +     + Gk+
  gi|1891969   222 LEDYSAHSNYVELALIEM-----GEEDIFPHVGRNARFHV----EDAGKE 262  

                   vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgG
                   vyP++tGtFG+vDFLHsv GE  D  tqsE +E++ A+  Ae+ ++ s  
  gi|1891969   263 VYPIITGTFGGVDFLHSVCGEFSDKATQSELQELQGAMANAERSENKSKI 312  

                   GdsrqRGlllfglnlgGsgssgtDFisLvsql.Pgv..GdGlAstARsLk
                                              L+++l+Pg+ +G   As+A +L+
  gi|1891969   313 -------------------------KELLAKLpPGIfgGKDEASKADELE 337  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                     ++A    n +  t ++   f    g                    ++ 
  gi|1891969   338 NNANAAAMGNIQ-ITPKEPEAFTEQIG--------------------EIV 366  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   k+iYPi+EF D i+ si   ie +P L  L+E +   +t+F+ +LLAP++
  gi|1891969   367 KQIYPIMEFHDEIMQSIAEFIENVPILPDLIEEVQNQVTIFVFSLLAPYI 416  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    Pi++qv   L  Gss +i++s ++q   +n+  C+dPtHsmLsKDHF+n
  gi|1891969   417 LPILNQVKSELETGSSEVIASSRDKQHIVFNDDDCTDPTHSMLSKDHFSN 466  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAa..
                   +Ln  AG +a++++ + vP i+  w+    P + +   i  vFHHPA  +
  gi|1891969   467 ILNEPAGQIASAVLRWAVPQIVQCWDGQADPEQTIDRIIQAVFHHPACvg 516  

                   ..rdEevEihrk.mfetvkkWirEtknrhelnslLssEsvKeghnHvlad
                    +rd  v   r+ mf+tv +W + + n++ l+  Ls E v +g+nH    
  gi|1891969   517 atRDRSVTQGRQvMFDTVGQWWNNQ-NKQSLRRKLSREGVENGQNHKADV 565  

                   qssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + + ++   + g      + gG G     + +   +    
  gi|1891969   566 HDKGHGCGKPLGMANNFSSSGGKGSSNPQIQQATDQV    602  

gi|291181387|gb|EFE37171.1|: domain 1 of 1, from 1 to 608: score 628.7, E = 5.7e-186
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma      + ++L  a++ +v  ++ AAFGAGni si ++EG n+RH
  gi|2911813     1    MAS-STSLSPLILTTALLFLVFASPTAAFGAGNIASISKIEGVNFRH 46   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDvL t+   +  +G+K+  m v  vYFGnWLRDYsqAvDvGs+K v
  gi|2911813    47 GDIEDVLLTLYMARaagGRKFSKMDVMHVYFGNWLRDYSQAVDVGSVKHV 96   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  +Ri+           +W+L Fl+fGY  +EFEvt +RLG+Y P EH
  gi|2911813    97 SAEAVRIL-----------IWILGFLTFGYGVDEFEVTTDRLGCYQPTEH 135  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYAD+ DAR++D+RLRGPvd+ rEL +D r+G+K YiA E     
  gi|2911813   136 IDNPLGYADGADARRYDPRLRGPVDkRRELSVDERTGLKHYIATED---- 181  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsAG vr  l  +i  GR Y       Gk  DL EALR LG  LH
  gi|2911813   182 IGI-DTSAGLVRRVLGDCIELGRQYA----RSGKKADLYEALRLLGTGLH 226  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Lie+     G rdvFpHvG +t i+l        +
  gi|2911813   227 CLEDYAAHSNYTELSLIEM-----GERDVFPHVGRNTMIQL----PGCRH 267  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++ A++  + + +  +
  gi|2911813   268 DVYPIVTGTFGGVDFLHSVMGEFSDKTTQSEIQCLEGAIEETQNQGNTKS 317  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           l                   L++++P+   G     +  + +
  gi|2911813   318 F-------LQ-----------------ELLAKIPSGIIGGNESGKMDEFQ 343  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   s+Aq q   +  t  +                              ++++
  gi|2911813   344 SNAQAQAQQENITPHEPEE--------------------WTRYLQDVTRQ 373  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   iYP+LE+ D i +sin  ie iP L  L+E+i E + +F+ ++LAP+v P
  gi|2911813   374 IYPVLEWHDNILKSINKAIENIPVLPELIEQIQEQINVFVFSVLAPYVLP 423  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qv   L  Gss +i++s ++ql  +n+   +dPtHsmLsKDHF+n+L
  gi|2911813   424 IINQVKAELETGSSEIIQSSKKEQLNIFNDDDATDPTHSMLSKDHFSNLL 473  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AG++a  +v++vvP i+  w+   v  +  ln i+ +vFHHPA r+ 
  gi|2911813   474 NEPAGKIAQEVVKWVVPQIMECWDDTNVDASRTLNRIITgVFHHPAHRdf 523  

                   ..dEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqs
                   ++d   +++r mf  v++W +E+    +++  Ls E v++g nH    + 
  gi|2911813   524 gdDGAADVRRMMFGAVEEWWQEK-GDDGVRRQLSREGVRKGENHKPGVHD 572  

                   sdssrsvs...agshtsnGadgGHGkvaGslWskikkr<-*
                     ++  v+ + +    + Ga gG G+  G   +++ k    
  gi|2911813   573 CGHGSGVPlklSKKPHGHGASGGYGR--GRQANELSKL    608  

gi|67904160|ref|XP_682336.1|: domain 1 of 1, from 1 to 610: score 628.0, E = 9e-186
                   *->magLrigwgsvLLvlavvLiv.LPdkAAAFGAGniPsiAqvEGknwR
                           +g +   L l + +iv+L + A AFGAGni si ++EG+nwR
  gi|6790416     1    -----MGVSFQKLCLLLFVIVsLSGGAHAFGAGNIASISKIEGQNWR 42   

                   HGDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKG
                   HGDiED L  +   +  +G+K+  + v+RvYFGnWLRDYsqAvDvG +K 
  gi|6790416    43 HGDIEDALLGLFLARaagGRKFNKLDVQRVYFGNWLRDYSQAVDVGTVKY 92   

                   vnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEE
                   v+A  iRi+            WvL Fl+fGY t+EFEvt ERLG+Y P E
  gi|6790416    93 VSAEAIRIL-----------LWVLGFLSFGYGTKEFEVTTERLGCYQPTE 131  

                   HiDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslay
                   HiDnP+gYA+++DAR++D RLRGPvd+ rEL +Dp++G+KnYiAnE+   
  gi|6790416   132 HIDNPLGYAEGEDARDYDRRLRGPVDeERELAVDPKTGLKNYIANER--- 178  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                        atsA  vr  + R++  GR Y         ++DL EALR LG  L
  gi|6790416   179 -INI-ATSAALVRRLFGRCVQLGRRYARSRN----DEDLHEALRLLGTGL 222  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED++AHsnY EL Liel     G ++vFpHvG dt++++        
  gi|6790416   223 HCLEDYAAHSNYVELSLIEL-----GESEVFPHVGRDTKVEI----EGVS 263  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                     vyP+vtGtFG+vDF HsvLGE  D  tqsE++E    L++A   s+ +
  gi|6790416   264 DPVYPIVTGTFGGVDFFHSVLGEISDKATQSEIQE----LEGAINESQNG 309  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlP....gvGdGlAstAR
                   +  ds    +l                  L+ ++P++  g  d   s+  
  gi|6790416   310 SPSDS----FL----------------QNLLDKIPegliGNSDEKVSRMD 339  

                   sLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpv
                   +LkA+s+   +qn +   r+                           D v
  gi|6790416   340 ELKAESEDAKKQNRHVSPRQPEEW-------------------TKYLDDV 370  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                   +  kkiYP+LE+ D + +sin  ieKiP L  L+E++ E +t+ + ++LA
  gi|6790416   371 Q--KKIYPVLEWHDELLKSINEAIEKIPVLPELIEQVQEQITIAVFSILA 418  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   P+v Pi++qv   L+ Gss +i++s ++q   +n+  C +PtHsmLsKDH
  gi|6790416   419 PYVLPILQQVKAELQTGSSEVIQSSRDQQHVVFNDDSCSNPTHSMLSKDH 468  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHP
                   F+n+Ln  AGRva+ iv++ vP ++  w+     ++  l  i+ +vFHHP
  gi|6790416   469 FSNILNEPAGRVASQIVKWTVPQLMELWDDEEADIEPTLDRIVSgVFHHP 518  

                   Aa....rdEevEihrkmfetvkkWirEtknrhelnsl...LssEsvKegh
                   A ++++rd   Ei+r mfetv+kW + +  ++e++sl+++Ls E v+eg+
  gi|6790416   519 ASrrggRDGAREIRRIMFETVQKWWEGK-SEREIRSLreqLSREGVREGR 567  

                   nHvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   nH  + + s ++   + + h +        k+     +ki +    
  gi|6790416   568 NHKESVHDSGHGCGKPLSLHKGPQNSSQRRKPEVGRIEKIASE    610  

gi|291186721|gb|EFE42141.1|: domain 1 of 1, from 1 to 608: score 627.4, E = 1.4e-185
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma      + ++L  a++ +v  ++ AAFGAGni si ++EG n+RH
  gi|2911867     1    MAS-STSLSPLILTTALLFLVFASPTAAFGAGNIASISKIEGVNFRH 46   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDvL t+   +  +G+K+  m v  vYFGnWLRDYsqAvDvGs+K v
  gi|2911867    47 GDIEDVLLTLYMARaagGRKFSKMDVMHVYFGNWLRDYSQAVDVGSVKHV 96   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  +Ri+           +W+L Fl+fGY  +EFEvt +RLG+Y P EH
  gi|2911867    97 SAEAVRIL-----------IWILGFLTFGYGVDEFEVTTDRLGCYQPTEH 135  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYAD+ DAR++D+RLRGPvd+ rEL +D r+G+K YiA E     
  gi|2911867   136 IDNPLGYADGADARRYDPRLRGPVDkRRELSVDERTGLKHYIATED---- 181  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsAG vr  l  +i  GR Y       Gk  DL EALR LG  LH
  gi|2911867   182 IGI-DTSAGLVRRVLGDCIELGRQYA----RSGKKADLYEALRLLGTGLH 226  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Lie+     G rdvFpHvG +t i+l        +
  gi|2911867   227 CLEDYAAHSNYTELSLIEM-----GERDVFPHVGRNTMIQL----PGCRH 267  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++ A++  + +s+  +
  gi|2911867   268 DVYPIVTGTFGGVDFLHSVMGEFSDKTTQSEIQCLEGAIEETQNQSNTKS 317  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           l                   L++++P+   G     +  + +
  gi|2911867   318 F-------LQ-----------------ELLAKIPSGIIGGNESGKMDEFQ 343  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   s+Aq q   +  t  +                              ++++
  gi|2911867   344 SNAQAQAQQENITPHEPEE--------------------WTRYLQDVTRQ 373  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   iYP+LE+ D i +sin  ie iP L  L+E+i E + +F+ ++LAP+v P
  gi|2911867   374 IYPVLEWHDNILKSINKAIENIPVLPELIEQIQEQINVFVFSVLAPYVLP 423  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qv   L  Gss +i++s ++ql  +n+    dPtHsmLsKDHF+n+L
  gi|2911867   424 IINQVKAELETGSSEIIQSSKKEQLNIFNDDDASDPTHSMLSKDHFSNLL 473  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AG++a  +v++vvP i+  w+   v  +  ln i+ +vFHHPA r+ 
  gi|2911867   474 NEPAGKIAQEVVKWVVPQIMECWDDTNVDASRTLNRIITgVFHHPAHRdf 523  

                   ..dEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqs
                   ++d   +++r mf  v++W +E+    +++  Ls E v +g nH    + 
  gi|2911867   524 gdDGAADVRRMMFGAVEEWWQEK-GDDGVRRQLSREGVMKGENHKPGVHD 572  

                   sdssrsvs...agshtsnGadgGHGkvaGslWskikkr<-*
                     ++  v+ + +    + Ga gG G+  G   +++ k    
  gi|2911867   573 CGHGSGVPlklSKKPHGHGASGGYGR--GRQANELSKL    608  

gi|119489357|ref|XP_001262889.1|: domain 1 of 1, from 1 to 610: score 616.3, E = 3.1e-182
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                          +  +   L +  ++L+ L +kA AFGAGni si qvEG+nwRH
  gi|1194893     1    ----MGSSVQSLTLSILLLLLLSGKAQAFGAGNIASISQVEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED+L t+   +  +G+K+  + v+RvYFGnWLRDYsqAvDvG LK v
  gi|1194893    44 GDIEDTLLTLFLARaagGRKFGKLDVQRVYFGNWLRDYSQAVDVGTLKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iRi+           +WvL Fl+fGY t+EFEvt ERLG+Y P EH
  gi|1194893    94 SAEAIRIL-----------IWVLGFLSFGYGTKEFEVTTERLGCYEPTEH 132  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYA+++DAR++D RLRGPvd+ rEL +Dpr+G+KnYiA E     
  gi|1194893   133 IDNPLGYAEGEDARRYDRRLRGPVDeERELSVDPRTGLKNYIASED---- 178  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsAG vr  ++R++  GR Y         ++DL EALR LG  LH
  gi|1194893   179 LGI-GTSAGLVRRVFKRSVELGRRYARSRN----DDDLHEALRLLGTGLH 223  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Liel     G + vFpHvG +t++++         
  gi|1194893   224 CLEDYAAHSNYTELSLIEL-----GESTVFPHVGRNTKVEV----DGAQD 264  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    +yP+vtGtFG+vDF HsvLGE  D   qsEv+     L++    s+s+ 
  gi|1194893   265 YIYPIVTGTFGGVDFFHSVLGELSDKTIQSEVQ----SLEGVINESQSGT 310  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsq.lPgvGdGlAstARsLkA
                     +s    l+              D +  + ++l g  d  A +  + kA
  gi|1194893   311 PSES----LI-------------QDLLNKIPEgLIGNSDDQANKMDEFKA 343  

                   asaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktak
                   +s+   q+n +   r+                           D v   +
  gi|1194893   344 KSQNAKQHNQEISPREPEEW-------------------TRYLDNVH--Q 372  

                   kiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvR
                   +iYP+LE+ D +++sin  ie iP L  L+E+  E + +F+ ++LAP++ 
  gi|1194893   373 QIYPVLEWHDELIKSINRAIEEIPVLPELIEQFQEQINIFVFSILAPYIL 422  

                   PiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnv
                   Pii qv   L+ Gss +ie+s  +q   +n+    +PtHsmLsKDHF+nv
  gi|1194893   423 PIIRQVKVELQTGSSEVIESSRAQQHVVFNDDDSSNPTHSMLSKDHFSNV 472  

                   LnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar.
                   Ln  AG +a+ +v++ vP ++  w+   + vd  l  i+ +vFHHPA+r+
  gi|1194893   473 LNEPAGQIASRVVKWTVPQLMECWDDENIDVDRTLDRIITgVFHHPALRq 522  

                   ...dEevEihrkmfetvkkW..irEtknrhelnslLssEsvKeghnHvla
                    ++d   +i++ mf+tv++W + +++ +++ l++ Ls E v+eg+nH   
  gi|1194893   523 ygeDGASDIRQIMFNTVEEWwgRKDEAEQESLREQLSREGVREGKNHKEG 572  

                   dqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    + s ++   +   h +  + g   k++ s   ki      
  gi|1194893   573 VHDSGHGCGKPITLHRAKTSPGESYKPSTSGLGKIAAE    610  

gi|70982294|ref|XP_746675.1|: domain 1 of 1, from 1 to 610: score 614.1, E = 1.4e-181
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                          +  +   L +  ++L+ L +kA AFGAGni si qvEG+nwRH
  gi|7098229     1    ----MGSSVQSLTLSILLLLLLSEKAHAFGAGNIASISQVEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED+L t+   +  +G+K+  + v+RvYFGnWLRDYsqAvDvG LK v
  gi|7098229    44 GDIEDTLLTLFLARaagGRKFGKLDVQRVYFGNWLRDYSQAVDVGTLKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iRi+           +WvL Fl+fGY t+EFEvt ERLG+Y P EH
  gi|7098229    94 SAEAIRIL-----------IWVLGFLSFGYGTKEFEVTTERLGCYDPTEH 132  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYA+++DAR++D RLRGPvd+ rEL +Dpr+G+KnYiA E     
  gi|7098229   133 IDNPLGYAEGEDARRYDRRLRGPVDeERELSVDPRTGLKNYIASED---- 178  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                        tsAG vr  ++R++  GR Y         +++L EALR LG  LH
  gi|7098229   179 LSI-GTSAGLVRRVFKRSVELGRRYARSRN----DDELHEALRLLGTGLH 223  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Liel     G + vFpHvG +t++ +         
  gi|7098229   224 CLEDYAAHSNYTELSLIEL-----GESTVFPHVGRNTKVKV----DGAQD 264  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    +yP+vtGtFG+vDF HsvLGE  D   qsEv+     L++    s+s+ 
  gi|7098229   265 YIYPIVTGTFGGVDFFHSVLGELSDKTIQSEVQ----SLEGVINESQSGT 310  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsq.lPgvGdGlAstARsLkA
                     +s    l+              D +  + ++l g  d  A +  + kA
  gi|7098229   311 PTES----LI-------------QDLLNKIPEgLIGNSDDQANKMDEFKA 343  

                   asaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktak
                   +s+   qqn +   r+                           D v   +
  gi|7098229   344 KSQNAKQQNQEISPREPEEW-------------------TRYLDNVH--Q 372  

                   kiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvR
                   +iYP+LE+ D +++sin  ie iP L  L+E+  E + +F+ ++LAP++ 
  gi|7098229   373 QIYPVLEWHDELIKSINRAIEEIPVLPELIEQFQEQINIFVFSILAPYIL 422  

                   PiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnv
                   Pii qv   L+ Gss +ie+s  +q   +n+    +PtHsmLsKDHF+nv
  gi|7098229   423 PIIRQVKVELQTGSSEVIESSRAQQHVVFNDDDSSNPTHSMLSKDHFSNV 472  

                   LnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar.
                   Ln  AG +a+ +v++ vP ++  w+   + vd vl  i+ +vFHHPA+r+
  gi|7098229   473 LNEPAGQIASRVVKWTVPQLMECWDDENIDVDRVLDRIITgVFHHPALRq 522  

                   ...dEevEihrkmfetvkkW..irEtknrhelnslLssEsvKeghnHvla
                    ++d   +i++ mf+tv++W + +++ +r+ l++ Ls E v+eg+nH   
  gi|7098229   523 ygeDGASDIRQIMFDTVEEWwgKKDEAERESLREQLSREGVREGKNHKEG 572  

                   dqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    + s ++   +   h +  + g   k++ s   ki      
  gi|7098229   573 VHDSGHGCGKPLTLHKAKTSPGESYKPSTSGLGKIAAE    610  

gi|255954861|ref|XP_002568183.1|: domain 1 of 1, from 1 to 608: score 606.3, E = 3.2e-179
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m       g  LL+    L+   ++A AFGAGni s+ ++EG+nwRH
  gi|2559548     1    MGLSLQNLGLSLLI----LVAFSGQAYAFGAGNIASLSRLEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L t+   +  +GkK+  + v+RvYFGnWLRDYsqAvDvG +K v
  gi|2559548    44 GDIEDALLTLYMARvagGKKFGKLDVKRVYFGNWLRDYSQAVDVGTVKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iRi+            WvL F++fGY t EFEvt ERLG+Y P EH
  gi|2559548    94 SAEAIRIL-----------LWVLGFMSFGYGTGEFEVTTERLGCYQPTEH 132  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYA ++DAR++D RLRGPvd+ rEL +Dpr+G+K YiA E     
  gi|2559548   133 IDNPLGYATGEDARDYDRRLRGPVDeERELAVDPRTGLKHYIATED---- 178  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA  +r  l R+i  GR Y       G  +DL EALR LG  LH
  gi|2559548   179 VGI-DTSATLIRRVLGRSIQLGRRYG----RSGNKDDLYEALRLLGTGLH 223  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Lie+     G r+vFpHvG dt++++        +
  gi|2559548   224 CLEDYAAHSNYTELSLIEM-----GEREVFPHVGRDTKLQV----DGVDE 264  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDF HsvLGE  D   qsE + ++  +   e    s +
  gi|2559548   265 EVYPIVTGTFGGVDFFHSVLGELSDKTMQSELETLENVVAESENPDSSES 314  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           l                   L+s++P   +Gl     +   +
  gi|2559548   315 F-------LQ-----------------TLLSKIP---EGLLGDSNDQTGQ 337  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                    +    +       ++ n           p  p    +  +     + k+
  gi|2559548   338 MDDFKSKADD-AKHDSENI---------SPREPEEWALYLD----NVQKQ 373  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   +YP+LE+ D + + in  ieKiP L  L+E+i + +t+F+ ++LAP+v P
  gi|2559548   374 VYPVLEWHDNLLKRINEAIEKIPVLPELIEQIQDQITIFVFSVLAPYVLP 423  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii qv   L  Gss +i++s ++q   +n+  C +PtHsmLsKDHF+n+L
  gi|2559548   424 IIRQVKSELETGSSEVIQSSREQQHIVFNDDDCSNPTHSMLSKDHFSNIL 473  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa...
                   n  AGR+a+++v++ vP ++  w+   v +d  l  i+ +vFHHPA ++ 
  gi|2559548   474 NEPAGRIASAVVKWSVPQLMSCWDDEDVDIDRTLDRIISgVFHHPARrey 523  

                   .rdEevEihrkmfetvkkWirEt..knrhelnslLssEsvKeghnHvlad
                   +rd   ++h+ mf tv+kW +E+++++r  l++ Ls + v eg+nH    
  gi|2559548   524 gRDGASDMHQIMFSTVEKWWNEKddEERDILREQLSRDGVLEGRNHKDGV 573  

                   qssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   q   ++   + +     G   G G+ +Gs  s i++    
  gi|2559548   574 QDCGHGCGKPIALPKPHGGSSGEGQGSGS--SGIENL    608  

gi|238843618|gb|EEQ33280.1|: domain 1 of 1, from 1 to 608: score 602.8, E = 3.5e-178
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma        v+L  a++ +v  ++AAAFGAGni s  ++EG n+RH
  gi|2388436     1    MAS--SSLTPVILTTALLFLVFANPAAAFGAGNIASFSKIEGSNFRH 45   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDvL t+   ++ +G+K+  m v  vYFGnWLRDYsqAvDvG +K v
  gi|2388436    46 GDIEDVLLTLYMARsagGRKFSKMDVTHVYFGNWLRDYSQAVDVGTVKHV 95   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  +Ri+           +W+L Fl+fGY  +EFEvt +RLG+Y P EH
  gi|2388436    96 SAEAVRIL-----------IWILGFLTFGYGVDEFEVTADRLGCYQPTEH 134  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYAD+ DAR++D RLRGPvd+ rEL iD r+G+KnYiA E     
  gi|2388436   135 IDNPLGYADGADARQYDRRLRGPVDkRRELSIDERTGLKNYIASED---- 180  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA  +r  l  +i  GR         G   DL EALR LG  LH
  gi|2388436   181 LGI-DTSADLIRRVLGGCIKLGRKHA----RSGNKADLYEALRLLGTGLH 225  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Lie+     G rd+FpHvG +t+i+l        +
  gi|2388436   226 CLEDYAAHSNYTELSLIEM-----GERDIFPHVGRNTKIQL----PGAQH 266  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv+GE  D  tqsE++     L++A   ++  g
  gi|2388436   267 SVYPIVTGTFGGVDFLHSVMGEFSDKATQSEIQ----TLEGAIAETQNQG 312  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                   G +s    +l                  L++++P+   G     +  + +
  gi|2388436   313 GAKS----FL----------------QELLAKIPAGIIGGNESGKMDEFQ 342  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   s+Aq q   +       nv             p  P     +    ++++
  gi|2388436   343 SNAQAQAQQE-------NV------------SPHEPEAWTRYLQ-DVTRQ 372  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   +YP+LE+ D + ++in  i+ iP L  L+E+i E + +F+ +++AP+v P
  gi|2388436   373 VYPVLEWHDNLLKTINKAIQNIPILPELIEQIQEQINIFVFSVIAPYVLP 422  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qv   L  Gss +i++s ++q   +n+   +dPtHsmLsKDHF+n+L
  gi|2388436   423 IINQVKAELETGSSEIIQSSKKEQHNIFNDDDSTDPTHSMLSKDHFSNLL 472  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AG++a  +v++ vP i+  w+   + v+  ln i+ +vFHHPA r+ 
  gi|2388436   473 NEPAGKIAQQVVKWAVPQIMECWDDENIDVNRTLNRIITgVFHHPAHRdf 522  

                   ..dEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnH....vl
                   ++d   +++r mf  v++W rE     +++  Ls + v++g nH+++   
  gi|2388436   523 gdDGAADVRRMMFGVVEEWWREN-GDNGVRRQLSRDGVRNGENHkpgvHD 571  

                   adqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    ++ s +   +s  s  ++G+ gG G+  G   +++ k    
  gi|2388436   572 CGHGSGKPLKLSKKSNHGSGSTGGYGQ--GTQANELGKL    608  

gi|240107631|gb|EER25810.1|: domain 1 of 1, from 1 to 619: score 602.2, E = 5.3e-178
                   *->magLrigwgsvLLvlavvLi.vLPdkAAAFGAGniPsiAqvEGknwR
                      ma     + s L+  + +L+ +   +AAAFGAGni s+ ++EG+nwR
  gi|2401076     1    MAV----STSTLIATTFLLVlIFAHPAAAFGAGNIASLSRIEGQNWR 43   

                   HGDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKG
                   HGDiED L  v   +  +GkK+  + ++RvYFGnWLRDYsqAvDvG +K 
  gi|2401076    44 HGDIEDALLSVVMARvagGKKFSKLDLQRVYFGNWLRDYSQAVDVGTVKY 93   

                   vnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEE
                   v+A  iRi+            WvL Fl+fGY t EFEvt ERLG Y P E
  gi|2401076    94 VSAEAIRIL-----------LWVLGFLSFGYGTGEFEVTTERLGTYQPTE 132  

                   HiDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslay
                   HiDnP+gYA+++DAR++D RLRGP+d+ rEL iD r+G+K YiA E    
  gi|2401076   133 HIDNPLGYAEGDDARRYDRRLRGPIDeERELAIDTRTGLKHYIATED--- 179  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                     G  atsAG +r  + R+i  GR Y   sr k    +L EALR LG  L
  gi|2401076   180 -IGI-ATSAGLLRSVFGRCIELGRSYGR-SRDK---TELYEALRLLGTGL 223  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED++AHsn+ EL Lie+     G +dvFpHvG  t ++l       G
  gi|2401076   224 HCLEDYAAHSNFTELCLIEM-----GEQDVFPHVGRRTMMEL----PGVG 264  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                     vyP++tGtFG+vDFLHsv+GE  D  tqsE +     L++  ++s++ 
  gi|2401076   265 YPVYPIITGTFGGVDFLHSVMGEFSDKATQSELQ----SLEGVMEQSQGE 310  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg.vGdGlAstARsLk
                   gG    ++ ++                  L+ ++P+++  G     +  +
  gi|2401076   311 GG----NKSFI----------------KDLLDKIPSeIFGGQDNSGKMDE 340  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                    +++Aq qq s                                 D vkt 
  gi|2401076   341 FQANAQHQQQSPPHVSPKEPE-----------------EWTEYLDNVKT- 372  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                    ++YP+LE+ D +++si   ieKiP L  L+E++   + +F+ +++AP+v
  gi|2401076   373 -QVYPVLEWHDNLMKSISEAIEKIPVLPDLIEQVQNEINVFVFSVIAPYV 421  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    Pii+qv   L  Gss +i++s ++q   +nn  C+dPtHsmLsKDHF+n
  gi|2401076   422 IPIINQVKTELETGSSEVIQSSRDQQHNIFNNDDCTDPTHSMLSKDHFSN 471  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar
                   vLn  AG+va  +v++ vP i+ Aw+   + vd  l  i+++vFHHPA r
  gi|2401076   472 VLNEPAGKVAQEVVKWAVPQIMDAWDDEYIDVDRTLTRIIHgVFHHPAHR 521  

                   ....dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnHv.
                   ++++d + +i+  mf  v++W +E+ +r++  l+  Ls E v++g nH +
  gi|2401076   522 nhgqDGQSDIRMLMFGAVEQWWNEQGRRgqDSLRRQLSREGVRNGDNHKp 571  

                   .ladqssdssrsvsagshts.....nGadgGHGkv..aGslWskikkr<-
                   +  d  +  ++ +s + h s++++  G + G G+++++  l    kk   
  gi|2401076   572 gVRDTGHGCGKPLSLPKHKSkntgvLGGLSGAGRTrdTDELAHMAKKA   619  

                   *
                    
  gi|2401076     -   -    

gi|119177578|ref|XP_001240545.1|: domain 1 of 1, from 1 to 619: score 602.2, E = 5.6e-178
                   *->magLrigwgsvLLvlavvLi.vLPdkAAAFGAGniPsiAqvEGknwR
                      ma     + s L+  + +L+ +   +AAAFGAGni s+ ++EG+nwR
  gi|1191775     1    MAV----STSTLIATTFLLVlIFAHPAAAFGAGNIASLSRIEGQNWR 43   

                   HGDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKG
                   HGDiED L  v   +  +GkK+  + ++RvYFGnWLRDYsqAvDvG +K 
  gi|1191775    44 HGDIEDALLSVVMARvagGKKFSKLDLQRVYFGNWLRDYSQAVDVGTVKY 93   

                   vnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEE
                   v+A  iRi+            WvL Fl+fGY t EFEvt ERLG Y P E
  gi|1191775    94 VSAEAIRIL-----------LWVLGFLSFGYGTGEFEVTTERLGTYQPTE 132  

                   HiDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslay
                   HiDnP+gYA+++DAR++D RLRGP+d+ rEL iD r+G+K YiA E    
  gi|1191775   133 HIDNPLGYAEGDDARRYDRRLRGPIDeERELAIDARTGLKHYIATED--- 179  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                     G  atsAG +r  + R+i  GR Y   sr k    +L EALR LG  L
  gi|1191775   180 -IGI-ATSAGLLRNVFGRCIELGRSYGR-SRDK---TELYEALRLLGTGL 223  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED++AHsn+ EL Lie+     G +dvFpHvG  t ++l       G
  gi|1191775   224 HCLEDYAAHSNFTELCLIEM-----GEQDVFPHVGRRTMMEL----PGVG 264  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                     vyP++tGtFG+vDFLHsv+GE  D  tqsE +     L++  ++s++ 
  gi|1191775   265 YPVYPIITGTFGGVDFLHSVMGEFSDKATQSELQ----SLEGVMEQSQGE 310  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg.vGdGlAstARsLk
                   gG    ++ ++                  L+ ++P+++  G     +  +
  gi|1191775   311 GG----NKSFI----------------KDLLDKIPSeIFGGQDNSGKMDE 340  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                    +++Aq qq s                                 D vkt 
  gi|1191775   341 FQANAQHQQQSPPHVSPKEPE-----------------EWTEYLDNVKT- 372  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                    ++YP+LE+ D +++si   ieKiP L  L+E++   + +F+ +++AP+v
  gi|1191775   373 -QVYPVLEWHDNLMKSISEAIEKIPVLPDLIEQVQNEINVFVFSVIAPYV 421  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    Pii+qv   L  Gss +i++s ++q   +nn  C+dPtHsmLsKDHF+n
  gi|1191775   422 IPIINQVKTELETGSSEVIQSSRDQQHNIFNNDDCTDPTHSMLSKDHFSN 471  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar
                   vLn  AG+va  +v++ vP i+ Aw+   + vd  l  i+++vFHHPA r
  gi|1191775   472 VLNEPAGKVAQEVVKWAVPQIMDAWDDEYIDVDRTLTRIIHgVFHHPAHR 521  

                   ....dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnHv.
                   + ++d + +i+  mf  v++W +E+ +r++  l+  Ls E v++g nH +
  gi|1191775   522 nygqDGQSDIRMLMFGAVEQWWNEQGRRgqDSLRRQLSREGVRNGDNHKp 571  

                   .ladqssdssrsvsagshts.....nGadgGHGkv..aGslWskikkr<-
                   +  d  +  ++ +s + h s++++  G + G G+++++  l    kk   
  gi|1191775   572 gVRDTGHGCGKPLSLPKHKSkntgvLGGLSGAGRTqdTDELAHMAKKA   619  

                   *
                    
  gi|1191775     -   -    

gi|58262802|ref|XP_568811.1|: domain 1 of 1, from 1 to 585: score 597.5, E = 1.4e-176
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma      + +LL++a+v +       AFGAGniPs   +E k +RH
  gi|5826280     1    MA----KTALLLLLVALVTLSFTPGVYAFGAGNIPSFSYLEEKAFRH 43   

                   GDiEDvLKtv......AFi.kGkKWttmmvgRvYFGnWLRDYsqAvDvGs
                   GDiED++ ++ +  ++ F+++G K+t + v+RvYFGnWLRDYsqAvDvGs
  gi|5826280    44 GDIEDIIANLfkaaggGFLsRGTKFTPLDVKRVYFGNWLRDYSQAVDVGS 93   

                   LKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYR
                   LK  n  ti  i           v vL F+a+GYAt EFEvt +RLG+Y 
  gi|5826280    94 LKKTNLQTIINI-----------VMVLGFMAHGYATGEFEVTKDRLGCYL 132  

                   PEEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEsl
                   P EHiDnPkgYAD++DAR++D+RLRGPvdPrELEiDpr+GmKnYiAnE  
  gi|5826280   133 PTEHIDNPKGYADGEDARQYDSRLRGPVDPRELEIDPRTGMKNYIANEN- 181  

                   ayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGq
                      gGW ats   vr  l+ +iH+GR Y s        sDL EA   LG 
  gi|5826280   182 ---GGW-ATSKALVRQRLQECIHYGRQYRSNNNK----SDLYEAFQLLGR 223  

                   ALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrn
                   ALH+lEDF+AHsn+CELaLi +     Gy +vFpH+G + ++        
  gi|5826280   224 ALHTLEDFTAHSNWCELALISF-----GYTNVFPHIGQNVKVRA-----P 263  

                   nGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqask
                   nG+ vyPLvtGtFG+ DF+Hs +GEAtDH  q+ v ++   +  A   s+
  gi|5826280   264 NGRDVYPLVTGTFGGADFIHSLMGEATDHLSQASVSDLSKQMTNARSVSE 313  

                   ssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsL
                   + +      R l+                      +Pg G+G  s  R+L
  gi|5826280   314 GQSSSADTLRQLF--------------------FSIPG-GEG-DSMTRDL 341  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   +        qn+r                +g p g     msP+    + 
  gi|5826280   342 EG------IQNMR----------------AGQPGGVDPSTMSPQ----EL 365  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    + i+ iL FRD +++ i n+i++iPGL  L+Ekis  + +Fi+  L PF
  gi|5826280   366 HQTIWQILSFRDSVMKKIENTIDRIPGLSGLVEKISNSVSVFIITTLEPF 415  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   v+P++   +++L + s ++i++  + q+E Wn+    dPtHs LsKDHF 
  gi|5826280   416 VKPLLGTATEALGQSSQAVIDS--HDQYEVWNDRNASDPTHSFLSKDHFG 463  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar
                    +Ln  AG +a  +v   v  ++ Aw+   +  + v +  L +  HP   
  gi|5826280   464 LLLNQPAGEIARIVVEHTVNLVVKAWDDNNINPSQVTETALEALFHPDFA 513  

                   dEevEihrkmfetvkkWirEt.knrhelnslLssEsvKeghnHvladqss
                     +  i+++m + +++Wi+ t+ n+ e+ + L+s+ vK+g+n    d s 
  gi|5826280   514 SGHSQIQKQMLDKMREWINSTgSNKNEILHRLTSDMVKQGKNRRIGDTSA 563  

                   dssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                     +              +    + G l + i ++   
  gi|5826280   564 TTG------------HVHNQLLPEGGLQQVIAQQ    585  

gi|256735483|gb|EEU48829.1|: domain 1 of 1, from 1 to 599: score 596.9, E = 2.2e-176
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m   r +    LLv  v+L+ L ++A AFGAGni si +vEG+nwRH
  gi|2567354     1    MFSFRSHG---LLVGLVILVGLASPAFAFGAGNIASISKVEGQNWRH 44   

                   GDiEDvLKtvAF...ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L t+   + ++GkK+  + v R+YFGnWLRDYsqAvDvG +K v
  gi|2567354    45 GDIEDALLTLTLaraLNGKKFNKINVSRTYFGNWLRDYSQAVDVGTVKSV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++             vL F++fGY   EFEvt ERLG+YRPEEH
  gi|2567354    95 SAEAIRLL-----------LCVLGFMTFGYGSGEFEVTAERLGCYRPEEH 133  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnPk+YA++ DAR++D RLRGP+d+ rEL +Dp++GmKnYiAnE+    
  gi|2567354   134 IDNPKDYAENADARQYDRRLRGPIDeERELSVDPETGMKNYIANER---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA  vr  +  +i  GR Y    +   +  D  EALR +G  LH
  gi|2567354   180 AGI-MTSAKLVRRLFGGTIELGRKY----KDSQRKADKYEALRLMGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clEDF AHsnY ELaLiel     G rdvFpHvG +tei l      +G 
  gi|2567354   225 CLEDFFAHSNYTELALIEL-----GERDVFPHVGRNTEIDL------EGA 263  

                   r..vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqasks
                   r++vyP+vtGtFG+vDFLHsv GE  D  tq E+dE++  L+        
  gi|2567354   264 RgpVYPIVTGTFGGVDFLHSVTGEVSDKLTQNEIDELEGTLQQ------- 306  

                   sgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg..vGdGlAs.tAR
                                      G++s+ +    L+ ++P +  Gd + s++  
  gi|2567354   307 -------------------GAASDTSMLRDLLDKIPDgiFGDKHQSdRVD 337  

                   sLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpv
                   +L+  +a    +n     r+                              
  gi|2567354   338 ELQQNAATAQMENVSVSPRDPEEF---------------------TLYVQ 366  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                    + k++ P +EF D i++si   +eKiP L  ++E++ E L +Fi +++A
  gi|2567354   367 NVFKQVMPAIEFHDDIMKSISGALEKIPVLPKIIEQLEEQLSVFIFSIIA 416  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PF+ P+i+q+ + LK Gs  +ie+s ++q   + n    dPtHsmLsKDH
  gi|2567354   417 PFIVPLIQQIRNELKTGSDEIIESSEREQHIVFHNDNSSDPTHSMLSKDH 466  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiL.rvFHHP
                   F+n+Ln  AGR aa +v +vvP ++ A +   v vd  l Di++ + HHP
  gi|2567354   467 FSNILNEIAGRNAASMVHWVVPQLMDAIDDESVDVDRLLDDIIgGILHHP 516  

                   Aard...Eev.EihrkmfetvkkWirEt..knrhelnslLssEsvKeghn
                   A+rd ++ +v+E +r+ +e vk+W  E ++ +r++++  L+ + v++g n
  gi|2567354   517 AQRDmgnRKVqEGRRRCYENVKEWWGEMgdGQREDYRRKLTRDGVQNGEN 566  

                   HvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   H    q   ++       h+  G +       G   + i+ +   
  gi|2567354   567 HKEGVQDTGHG-------HGCVGKLKMRKLYGGP--ETIEDK    599  

gi|46107690|ref|XP_380904.1|: domain 1 of 1, from 1 to 612: score 591.1, E = 1.2e-174
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m   r +    LLv  v+L+ L ++A AFGAGni si +vEG+nwRH
  gi|4610769     1    MFTFRSHG---LLVGLVILVALASPAVAFGAGNIASISKVEGQNWRH 44   

                   GDiEDvLKtvA...FikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDi D L  + + + ++GkK+  + v RvYFGnWLRDYsqA+DvG +K v
  gi|4610769    45 GDITDALLILSqaqALNGKKFNKINVSRVYFGNWLRDYSQAIDVGTVKSV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++             vL F++fGY   EFEvt ERLG+YRPE+H
  gi|4610769    95 SAEAIRLL-----------LCVLGFMTFGYGSGEFEVTAERLGCYRPEDH 133  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnPk+YA++ DAR++D RLRGP+d+ rEL iDp++GmKnYiAnE+    
  gi|4610769   134 IDNPKDYAENVDARQYDERLRGPIDeERELSIDPETGMKNYIANER---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                        tsA  ++  +  +i   R Y    +   +  D  EALR +G  LH
  gi|4610769   180 ARI-MTSAKHIKKLFSGTIELARRY----KDSRRKADKYEALRLMGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clEDF AHsnYCELaLiel     G rdvFpHvG dt+i++      +G 
  gi|4610769   225 CLEDFFAHSNYCELALIEL-----GERDVFPHVGRDTQIEI------EGA 263  

                   r..vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqasks
                   r++vyP+vtGtFG+vDFLHsv GE  D  tq E++E++  L   +q  +s
  gi|4610769   264 RepVYPVVTGTFGGVDFLHSVTGEVSDKLTQNEIEELEGTL---QQGANS 310  

                   sgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg..vGdGlAs.tAR
                             +l                  L+ ++P +  Gd + s++  
  gi|4610769   311 DTS-------ML----------------RDLLDKIPDgiFGDKHQSdRVD 337  

                   sLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpv
                   +L+  +aA   +n     r+                              
  gi|4610769   338 ELQNSAAAAQMENTTVSPRDPEEF---------------------TQYIQ 366  

                   ktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLA
                    + k++ P +EF D i++ i   +e+iP L  ++E++ E L +Fi +++A
  gi|4610769   367 NVFKQVMPAIEFHDDIMKGISTAMERIPVLPKIIEQLEEQLSVFIFSIIA 416  

                   PFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDH
                   PF+ P+i+q+ + LK Gs  +i++s ++q   +n+ r +dPtHsmLsKDH
  gi|4610769   417 PFIVPLIQQIRNELKTGSDEIIASSEREQHIVFNDDRSTDPTHSMLSKDH 466  

                   FtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHP
                   F+n+Ln  AGR aa +vq+vvP ++ A +  G  vd  l Di+ +v HHP
  gi|4610769   467 FSNILNEIAGRNAASMVQWVVPQLMDAIDDDGTDVDRLLDDIVDgVLHHP 516  

                   Aard....EevEihrkmfetvkkWirEt..knrhelnslLssEsvKeghn
                   A+rd +++   E + + f+ +++W +E ++ +r+e++  L+ + v++g n
  gi|4610769   517 AQRDlgsrKAQEGRNRFFKGIEEWWQEMgdGQREEYRGKLTRDGVQNGEN 566  

                   Hvladqssdssrsvsagsht....snGadgGHGkvaGslWskikkr<-*
                   H    q   +++  ++    ++  + G +    k aG+  + i k    
  gi|4610769   567 HKEGVQDTGHGHGCAGKLKMrklyGGGPETLEDKIAGAAADAIFKG    612  

gi|50546531|ref|XP_500735.1|: domain 1 of 1, from 1 to 638: score 587.3, E = 1.7e-173
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                              g   L+  +vL+   + A AFGAGniPsi ++EG+n+RH
  gi|5054653     1    -------MGNNFLLFVLVLLLCASFAHAFGAGNIPSISKIEGQNFRH 40   

                   GDiEDvLKtvAFik..........GkKWttmmvgRvYFGnWLRDYsqAvD
                   GDiED+L  +A   +++  ++ ++GkK+  m ++RvYFGnWLRDYsqA+D
  gi|5054653    41 GDIEDTLAMLAMTAgggllsklrgGKKFDKMAIKRVYFGNWLRDYSQAID 90   

                   vGsLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLG
                   +  LK            l+s+l  a+vW+L  + fGY t EF vtEERLG
  gi|5054653    91 IATLK----------QGLTSELLTAIVWILGIMEFGYGTGEFQVTEERLG 130  

                   vYRPEEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAn
                    YR +EHiDnPkgY +++DA + D RLRGPv+P ELEiDp++GmKnYi n
  gi|5054653   131 TYRADEHIDNPKGYGEGEDAPRLDRRLRGPVQPIELEIDPETGMKNYICN 180  

                   EslayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRC
                   E+    g W  ts  Yvr s+ ++i  GR        +G  +   EALR 
  gi|5054653   181 ER----GNW-PTSSVYVRDSIHKCIALGR--------QGGSENQYEALRL 217  

                   LGqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrnd
                   LGqALH+lEDF+AHsnYCEL+L+e+     G+ +vFpHvG dt+inl   
  gi|5054653   218 LGQALHTLEDFPAHSNYCELVLMEM-----GF-NVFPHVGRDTQINL--- 258  

                   trnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAe.
                      +G rvyPL+tGtFG+ DF+Hs +G A+D     E+++++  + aA +
  gi|5054653   259 ---HGNRVYPLITGTFGGLDFVHSLIGAANDSLSEVEIEDVNNHVAAAAd 305  

                   .qaskssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAs
                   ++ ++   G   r+  + l  +     g  +   + +   +      +  
  gi|5054653   306 sKVTEMLKG-YLRKLPIKLPNIPDFSGGQREMSGVEIADMIDNYERDMQT 354  

                   tARsLkAasa.....AqEqqnsrqltranvnvfnappgstggppgpgv..
                     R+L    + +++ A  +  s +   ++ n++              +++
  gi|5054653   355 DTRDLYGGFEagpdyASSYTGSSRDFSDDPNQLSGDFQKLNMQNKMKIst 404  

                   PGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEt
                   P +s   D  k+ ++i P+L FRD i+  +  + + iPGL sL EkisEt
  gi|5054653   405 PDLS-KIDVKKIERRILPLLKFRDAIMYGLEKVFDSIPGLSSLTEKISET 453  

                   LtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCdd
                   +  F+ gL+ P v+P+i +v+k L  G+  +  +s + q+E W nPr +d
  gi|5054653   454 MSLFVFGLISPIVKPMIAAVTKGLHAGAGKV--TSGDDQIEVWKNPRATD 501  

                   PtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvln
                   PtHs LsKDHF+  Ln  AG+vaa iv+ vvP ++ Aw    +  + v n
  gi|5054653   502 PTHSQLSKDHFSLYLNEPAGKVAAVIVKHVVPLVVDAWSDKSIDPNSVTN 551  

                   DiLrvFHHPAardEevEihrkmfetvkkWirEt.knrhelnslLssEsvK
                    ++ v HHP     +  ++++m etvk+Wi+  + +++ +   Ls + v 
  gi|5054653   552 TMMEVMHHPSMC--RTPLQQQMKETVKEWINNLgAKKQVVLNGLSPDGVL 599  

                   eghnHvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   +g n  + +++++         h+++    G    +  +  k  k+   
  gi|5054653   600 NGANNTGGKKHDQGD-------HSGCSHASGSANLSAFMAGKFGKQ    638  

gi|240281027|gb|EER44530.1|: domain 1 of 1, from 1 to 620: score 585.5, E = 5.7e-173
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         + + +v+ +    +  AFGAGni s+ ++EG+nwRH
  gi|2402810     1    MAW---STTTTVALTCVLFLLFTRPVHAFGAGNIASVSKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED + t+   ++ +GkK+  + v+R+YFGnWLRDYsqA+D+G LK v
  gi|2402810    45 GDIEDAILTLMMARsagGKKFSKLQVQRIYFGNWLRDYSQALDIGTLKYV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++            WvL F++fGY t EFEvt +R+G+Y P EH
  gi|2402810    95 SAEAIRLL-----------LWVLGFMTFGYGTGEFEVTLDRVGCYQPTEH 133  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gY +++DAR++  RLRGPvd+ rEL iD r+G+KnYiA E     
  gi|2402810   134 IDNPLGYGEGQDARRYYRRLRGPVDeERELGIDARTGLKNYIASED---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G    sA  +r  +  +i  GR Y   sr + ++ DL EALR LG  LH
  gi|2402810   180 LGI-DNSASLLRKVFGNCIELGRRY---SRSR-RDADLYEALRLLGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   +lED+ AHsnY EL Liel     G  +vFpHvG +t i+l    +    
  gi|2402810   225 TLEDYLAHSNYTELSLIEL-----GETNVFPHVGRNTMIQL----QGARN 265  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  ++  e ++    
  gi|2402810   266 SVYPIVTGTFGGVDFLHSVMGEISDKATQSEIQNLEGMIEESENQKP--- 312  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                        q G+l                  L+ ++P   +Gl     + +  
  gi|2402810   313 -----QEGFL----------------QVLLDKIP---EGLLGSEDNTEKM 338  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                    + q    s    r n n              p  P     +    + ++
  gi|2402810   339 NEFQSNAEST--KRRNENI------------SPREPEQWATYMN-DVQQQ 373  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   ++P+LE+ D +++sinn ieKiP +  L+E++ E +t+F+ +++AP+v P
  gi|2402810   374 MFPLLEWHDNLIKSINNAIEKIPTIPELVEQVQEQITIFVFSVMAPYVLP 423  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   i++qv   L  Gss +i++s + q+  +nn rC+dPtHsmLsKDHF+n+L
  gi|2402810   424 ILKQVKTELETGSSEVIQSSKEGQFNTFNNDRCTDPTHSMLSKDHFSNLL 473  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AG+ a+ +v++vvP i+  w+   + v+  +n i+ +vFHHPA+r+ 
  gi|2402810   474 NEPAGKAASEVVKWVVPQIMECWDDENIDVNRTMNRIINgVFHHPALRqy 523  

                   ..dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnH....
                   ++d   E++r+mf  ++ W +E+ +r++  l++ Ls E v++g nH+++ 
  gi|2402810   524 geDGSQEMRRTMFGVIESWWNEQGRRgqDSLRQQLSREGVRNGDNHkpgv 573  

                   ....vladqss...dssrsvsagshtsnGadgGHGkvaGslWskikkr<-
                   ++++ + +++++ ++++r v++g     G +g  Gk +    s+i+k   
  gi|2402810   574 hdsgHGCGKPMglpNRNRPVPGGVQDLLGLQGLGGKSSTNT-SNIEKM   620  

                   *
                    
  gi|2402810     -   -    

gi|225562540|gb|EEH10819.1|: domain 1 of 1, from 1 to 620: score 583.0, E = 3.3e-172
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         + + +v+ +    +  AFGAGni s+ ++EG+nwRH
  gi|2255625     1    MAW---STTTTVALTCVLFLLFTRPVHAFGAGNIASVSKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED + t+   ++ +GkK+  + v+R+YFGnWLRDYsqA+D+G LK v
  gi|2255625    45 GDIEDAILTLMMARsagGKKFSKLQVQRIYFGNWLRDYSQALDIGTLKYV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++            WvL F++fGY t EFEvt +R+G+Y P EH
  gi|2255625    95 SAEAIRLL-----------LWVLGFMTFGYGTGEFEVTLDRVGCYQPTEH 133  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gY +++DAR++  RLRGPvd+ rEL iD r+G+KnYiA E     
  gi|2255625   134 IDNPLGYGEGQDARRYYRRLRGPVDeERELGIDARTGLKNYIASED---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G    sA  +r  +  +i  GR Y   sr + ++ DL EALR LG  LH
  gi|2255625   180 LGI-DNSASLLRKVFGNCIELGRRY---SRSR-RDADLYEALRLLGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   +lED+ AHsnY EL Liel     G  +vFpHvG +t i+l    +    
  gi|2255625   225 TLEDYLAHSNYTELSLIEL-----GETNVFPHVGRNTMIQL----QGARN 265  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv+GE tD  tqsE++ ++  ++  e ++    
  gi|2255625   266 SVYPIVTGTFGGVDFLHSVMGEITDKATQSEIQNLEGMIEESENQKP--- 312  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                        q G+l                  L+ ++P   +Gl     + +  
  gi|2255625   313 -----QEGFL----------------QVLLDKIP---EGLLGSEDNTEKM 338  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                    + q    s    r n n              p  P     +    + ++
  gi|2255625   339 NEFQSNAEST--KRRNENI------------SPREPEQWATYMN-DVQQQ 373  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   ++P+LE+ D +++sin  ieKiP +  L+E++ E +t+F+ +++AP+v P
  gi|2255625   374 MFPLLEWHDNLIKSINSAIEKIPAIPELVEQVQEQITIFVFSVMAPYVLP 423  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   i++qv   L  Gss +i++s + q+  +nn rC+dPtHsmLsKDHF+n+L
  gi|2255625   424 ILKQVKTELETGSSEVIQSSKEGQFNTFNNDRCTDPTHSMLSKDHFSNLL 473  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AG+ a+ +v++vvP i+  w+   + v+  +n i+ +vFHHPA+r+ 
  gi|2255625   474 NEPAGKAASEVVKWVVPQIMECWDDENIDVNRTMNRIINgVFHHPALRqy 523  

                   ..dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnH....
                   ++d   E++r+mf  ++ W +E+ +r++  l++ Ls E v++g nH+++ 
  gi|2255625   524 geDGSQEMRRTMFGVIESWWNEQGRRgqDSLRQQLSREGVRNGDNHkpgv 573  

                   ....vladqss...dssrsvsagshtsnGadgGHGkvaGslWskikkr<-
                   ++++ + +++++ ++++r v++g     G + G G  +    s+i+k   
  gi|2255625   574 hdsgHGCGKPMglpNRNRPVPGGVQDMLG-LQGLGGNSSTNTSNIEKM   620  

                   *
                    
  gi|2255625     -   -    

gi|226292756|gb|EEH48176.1|: domain 1 of 1, from 1 to 622: score 582.8, E = 3.9e-172
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         +   +++ + L  +  AFGAGni s+ ++EG+nwRH
  gi|2262927     1    MAW---STTTTVAATCLLFLLLARPSHAFGAGNIASMSKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDv+ t+   ++ +GkK+  + v+R+YFGnWLRDYsqA+D+G +K v
  gi|2262927    45 GDIEDVILTLMMARsagGKKFSKLDVQRIYFGNWLRDYSQAIDIGTVKYV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iRi+             vL F++fGY t EFEvt ER+G+Y P EH
  gi|2262927    95 SAEAIRIL-----------LLVLGFMTFGYGTGEFEVTTERIGCYQPTEH 133  

                   iDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEslayq
                   iDnP+gY +++D R++  RLRGP+d +rEL iDpr+G+KnYiA E     
  gi|2262927   134 IDNPLGYGEGEDPRRYHRRLRGPIDEqRELGIDPRTGLKNYIASED---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G    sA  +r  + R+i  GR Y   sr +  EsDL EALR +G  LH
  gi|2262927   180 LGI-DNSAQLLRRLFGRCIELGRKY---SRSR-NESDLHEALRLMGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   +lED+ AHsnY EL Liel     G  d+FpHvG +t+++l    +    
  gi|2262927   225 TLEDYMAHSNYTELSLIEL-----GETDIFPHVGRNTKVQL----QGARD 265  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  +   e+ +    
  gi|2262927   266 KVYPIVTGTFGGVDFLHSVMGEISDKATQSEIQSLEGLIADSEKEQL--- 312  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlP.gvGdGlAstARsLkA
                        q G+l                  L+ ++P+g+  G  s  +  + 
  gi|2262927   313 -----QEGFL----------------QNLLDKVPnGLFGGDDSGTKMNEF 341  

                   asaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktak
                   +s+Aq  +          n              p  P    n+    + +
  gi|2262927   342 KSNAQSNKKRT------ENI------------SPREPEEWVNYLN-DVHQ 372  

                   kiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvR
                   ++YP+LE+ D +++sin  ie iPGL  ++E++ E L +F+ ++LAP+v 
  gi|2262927   373 QVYPLLEWHDNLMKSINKAIEAIPGLSDIVEQVQEQLNVFVFSVLAPYVL 422  

                   PiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnv
                   Pii+qv   L+ Gss +i++s  +q+  +n+  C+dPtHsmLsKDHF+n+
  gi|2262927   423 PIIKQVKFELQTGSSEVIQSSKAQQYNTFNDDYCTDPTHSMLSKDHFSNL 472  

                   LnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAard
                   Ln  AG+ aa iv +vvP i+  w+   + vd  +n i+ +v HHPA+rd
  gi|2262927   473 LNEPAGKAAAEIVRWVVPQIMECWDDESIDVDRTMNRIISgVLHHPALRD 522  

                   E....evEihrkmfetvkkWirEt..knrhelnslLssEsvKeghnH...
                    ++++  +++ +mf  v+ W +E++++ +  l+  Ls E v++g nH+++
  gi|2262927   523 YgedgAKDMRLTMFGIVESWWNEQggRGQDSLRRQLSREGVRNGDNHkpg 572  

                   .....vladqss...dssrsvsagshtsnGadgGHGkva.GslWskikkr
                    ++++ + +++++ + +s+ v++g+    G  g  Gk ++ s+ s+i+k 
  gi|2262927   573 vhdsgHGCGKPMtlpTRSHFVPGGAQDLFGLGGFSGKSSkQSMPSEIEKM 622  

                   <-*
                      
  gi|2262927     -     -    

gi|261205192|ref|XP_002627333.1|: domain 1 of 1, from 1 to 617: score 575.0, E = 8.3e-170
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         + v +++ +    +  AFGAGni si ++EG+nwRH
  gi|2612051     1    MAW---STTTTVAVTCLLFLLFTRPTHAFGAGNIASISKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDv+ t+   ++ +GkK+  m ++R+YFGnWLR    A+D+G +K v
  gi|2612051    45 GDIEDVILTLLMARsagGKKFSKMHLKRIYFGNWLR----AIDIGTVKYV 90   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++            WvL F++fGY t EFEvt +RLG+Y P EH
  gi|2612051    91 SAEAIRLL-----------LWVLGFMSFGYGTGEFEVTIDRLGCYQPTEH 129  

                   iDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEslayq
                   iDnP+gY +++D R++ +RLRGPvd +rEL iDpr+GmKnYiA E     
  gi|2612051   130 IDNPLGYGEGQDPRRYYSRLRGPVDEqRELGIDPRTGMKNYIATED---- 175  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G    sA  +r  +  +i  GR Y       G+E DL EALR LG  LH
  gi|2612051   176 LGI-DNSATLLRRIFGECIALGRRY----SRSGREADLFEALRLLGTGLH 220  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   +lED+ AHsnY EL Liel     G  ++FpHvG +t i+l    r    
  gi|2612051   221 TLEDYLAHSNYTELSLIEL-----GETNIFPHVGRNTMIEL----RGARN 261  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  +k  e ++    
  gi|2612051   262 PVYPIVTGTFGGVDFLHSVMGEISDKATQSEIQNLEGLIKESENQKP--- 308  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgv...GdGlAstARsL
                        q G+l                 +L+ ++P    +Gd    +  + 
  gi|2612051   309 -----QEGFL----------------QALLDKIPDSlfgGDDSTGKMNEF 337  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   +  ++   q+n +   r++                     m        +
  gi|2612051   338 QSNAESTKQRNENITPRESEAW---------------ATYMN------DV 366  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    +++YP+LE+ D +++sin  i+KiP L  L+E+  E +t+F+ +++AP+
  gi|2612051   367 HQQMYPLLEWHDNLMKSINEAIDKIPVLPELIEQAQEQITVFVFSVMAPY 416  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   v Pii qv + L  Gss +i+ s ++q+  + +  C+dPtHsmLsKDHF+
  gi|2612051   417 VLPIIRQVKQELETGSSEVIQNSKQEQFNTFTDDYCTDPTHSMLSKDHFS 466  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa
                   nvLn  AG+ a+ iv +vvP i+  w+   v vd v+n i+ +v HHPA+
  gi|2612051   467 NVLNEPAGKAASEIVRWVVPQIMECWDDESVDVDRVMNRIISgVLHHPAL 516  

                   r....dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnH.
                   r+ ++d   E++  mf  v+ W +E+ +r++  l++ L  E v++g nH+
  gi|2612051   517 ReygeDGAQEMRGIMFGVVESWWNEQGRRgqDSLRQQLRREGVQNGENHk 566  

                   .......vladqss...dssrsvsagshtsnGadgGHGkvaGslWskikk
                   ++ ++++ + +++++ +++ r v++g+    G +g   k++ s  s+i+k
  gi|2612051   567 pgvhdsgHGCGKPMglpNRDRPVAGGALDLFGLEGLRAKTSKSSASDIEK 616  

                   r<-*
                       
  gi|2612051   617 M    617  

gi|239611449|gb|EEQ88436.1|: domain 1 of 1, from 1 to 617: score 575.0, E = 8.3e-170
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         + v +++ +    +  AFGAGni si ++EG+nwRH
  gi|2396114     1    MAW---STTTTVAVTCLLFLLFTRPTHAFGAGNIASISKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiEDv+ t+   ++ +GkK+  m ++R+YFGnWLR    A+D+G +K v
  gi|2396114    45 GDIEDVILTLLMARsagGKKFSKMHLKRIYFGNWLR----AIDIGTVKYV 90   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++            WvL F++fGY t EFEvt +RLG+Y P EH
  gi|2396114    91 SAEAIRLL-----------LWVLGFMSFGYGTGEFEVTIDRLGCYQPTEH 129  

                   iDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEslayq
                   iDnP+gY +++D R++ +RLRGPvd +rEL iDpr+GmKnYiA E     
  gi|2396114   130 IDNPLGYGEGQDPRRYYSRLRGPVDEqRELGIDPRTGMKNYIATED---- 175  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G    sA  +r  +  +i  GR Y       G+E DL EALR LG  LH
  gi|2396114   176 LGI-DNSATLLRRIFGECIALGRRY----SRSGREADLFEALRLLGTGLH 220  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   +lED+ AHsnY EL Liel     G  ++FpHvG +t i+l    r    
  gi|2396114   221 TLEDYLAHSNYTELSLIEL-----GETNIFPHVGRNTMIEL----RGARN 261  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  +k  e ++    
  gi|2396114   262 PVYPIVTGTFGGVDFLHSVMGEISDKATQSEIQNLEGLIKESENQKP--- 308  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgv...GdGlAstARsL
                        q G+l                 +L+ ++P    +Gd    +  + 
  gi|2396114   309 -----QEGFL----------------QALLDKIPDSlfgGDDSTGKMNEF 337  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   +  ++   q+n +   r++                     m        +
  gi|2396114   338 QSNAESTKQRNENITPRESEAW---------------ATYMN------DV 366  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    +++YP+LE+ D +++sin  i+KiP L  L+E+  E +t+F+ +++AP+
  gi|2396114   367 HQQMYPLLEWHDNLMKSINEAIDKIPVLPELIEQAQEQITVFVFSVMAPY 416  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   v Pii qv + L  Gss +i+ s ++q+  + +  C+dPtHsmLsKDHF+
  gi|2396114   417 VLPIIRQVKQELETGSSEVIQNSKQEQFNTFTDDYCTDPTHSMLSKDHFS 466  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa
                   nvLn  AG+ a+ iv +vvP i+  w+   v vd v+n i+ +v HHPA+
  gi|2396114   467 NVLNEPAGKAASEIVRWVVPQIMECWDDESVDVDRVMNRIISgVLHHPAL 516  

                   r....dEevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnH.
                   r+ ++d   E++  mf  v+ W +E+ +r++  l++ L  E v++g nH+
  gi|2396114   517 ReygeDGAQEMRGIMFGVVESWWNEQGRRgqDSLRQQLRREGVQNGENHk 566  

                   .......vladqss...dssrsvsagshtsnGadgGHGkvaGslWskikk
                   ++ ++++ + +++++ +++ r v++g+    G +g   k++ s  s+i+k
  gi|2396114   567 pgvhdsgHGCGKPMglpNRDRPVAGGALDLFGLEGLRAKTSKSSASDIEK 616  

                   r<-*
                       
  gi|2396114   617 M    617  

gi|225680602|gb|EEH18886.1|: domain 1 of 1, from 1 to 627: score 570.5, E = 1.8e-168
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         +   +++ + L  +  AFGAGni s+ ++EG+nwRH
  gi|2256806     1    MAW---STTTTVAATCLLFLLLARPSHAFGAGNIASMSKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLR.....DYsqAvDvG
                   GDiEDv+ t+   ++ +GkK+  + v+R+YFGnWLR  +++DYsqA+D+G
  gi|2256806    45 GDIEDVILTLMMARsagGKKFSKLDVQRIYFGNWLRlipqkDYSQAIDIG 94   

                   sLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvY
                    +K v+A  iRi+             vL F++fGY t EFEvt ER+G+Y
  gi|2256806    95 TVKYVSAEAIRIL-----------LLVLGFMTFGYGTGEFEVTTERIGCY 133  

                   RPEEHiDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnE
                    P EHiDnP+gY +++D R++  RLRGP+d +rEL iDpr+G+KnYiA E
  gi|2256806   134 QPTEHIDNPLGYGEGEDPRRYHRRLRGPIDEqRELGIDPRTGLKNYIASE 183  

                   slayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCL
                         G    sA  +r  + R+i  GR Y   sr +  EsDL EALR +
  gi|2256806   184 D----LGI-DNSAQLLRRLFGRCIELGREY---SRSR-NESDLHEALRLM 224  

                   GqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndt
                   G  LH+lED+ AHsnY EL Liel     G  d+FpHvG +t+++l    
  gi|2256806   225 GTGLHTLEDYMAHSNYTELSLIEL-----GETDIFPHVGRNTKVQL---- 265  

                   rnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqa
                   +    +vyP+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  +   e+ 
  gi|2256806   266 QGARDKVYPIVTGTFGGVDFLHSVMGEISDKATQSEIQSLEGLIADSEKE 315  

                   skssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlP.gvGdGlAstA
                   +         q G+l                  L+ ++P+g+  G  s  
  gi|2256806   316 QL--------QEGFL----------------QNLLDKVPnGLFGGDDSGT 341  

                   RsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDp
                   +  + +s+Aq  +          n              p  P    n+  
  gi|2256806   342 KMNEFKSNAQSNKKRT------ENI------------SPREPEEWVNYLN 373  

                   vktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLL
                     + +++YP+LE+ D +++sin  ie iPGL  ++E++ E L +F+ ++L
  gi|2256806   374 -DVHQQVYPLLEWHDNLMKSINKAIEAIPGLSDIVEQVQEQLNVFVFSVL 422  

                   APFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKD
                   AP+v Pii+qv   L+ Gss +i++s  +q+  +n+  C+dPtHsmLsKD
  gi|2256806   423 APYVLPIIKQVKFELQTGSSEVIQSSKAQQYNTFNDDYCTDPTHSMLSKD 472  

                   HFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHH
                   HF+n+Ln  AG+ aa iv +vvP i+  w+   + vd  +n i+ +v HH
  gi|2256806   473 HFSNLLNEPAGKAAAEIVRWVVPQIMECWDDESIDVDRTMNRIISgVLHH 522  

                   PAardE....evEihrkmfetvkkWirEt..knrhelnslLssEsvKegh
                   PA+rd ++++  +++ +mf  v+ W +E++++ +  l+  Ls E v++g 
  gi|2256806   523 PALRDYgedgAKDMRLTMFGIVESWWNEQggRGQDSLRRQLSREGVRNGD 572  

                   nH........vladqss...dssrsvsagshtsnGadgGHGkva.GslWs
                   nH+++ ++++ + +++++ + +s+ v++g+    G  g  Gk ++ s+ s
  gi|2256806   573 NHkpgvhdsgHGCGKPMtlpTRSHFVPGGAQDLFGLGGFSGKSSkQSMPS 622  

                   kikkr<-*
                   +i+k    
  gi|2256806   623 EIEKM    627  

gi|39951367|ref|XP_363400.1|: domain 1 of 1, from 1 to 611: score 563.8, E = 2e-166
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+  +   s L++  + L     +A AFGAGni si  vEG+nwRH
  gi|3995136     1    MAFFNP---SHLIISLIFLFFFARPALAFGAGNIASISSVEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L  +A  +  +Gk +  + v RvYFGnWLRDYsqA+DvG +K v
  gi|3995136    45 GDIEDALLKIALARvagGKNFGKLDVLRVYFGNWLRDYSQAIDVGTVKNV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  +R++             +L Fl+fGY   EFEvt +RLG+YRPE+H
  gi|3995136    95 SAEAVRLL-----------LCILGFLTFGYGSREFEVTADRLGCYRPEDH 133  

                   iDnPkgYADikDARkfDaRLRGPvdPr.ELEiDprsGmKnYiAnEslayq
                   iDnPk+YAD+ DAR++D RLRGPvd ++EL +D ++G+KnYiAnE     
  gi|3995136   134 IDNPKNYADNADARQYDERLRGPVDEGtELAVDEETGLKNYIANEN---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA  vr  + R+i  GR Y    r + k sD  EALR LG  LH
  gi|3995136   180 AGI-MTSAQHVRNLFTRCIELGRSY---GRNRNK-SDFYEALRLLGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED+ AHsnY ELaLie+     G rdvFpHvG dt + +        +
  gi|3995136   225 CLEDYFAHSNYTELALIEM-----GERDVFPHVGRDTMMRI----PGARH 265  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv GE  D  tq E + ++  L+  +++  s  
  gi|3995136   266 EVYPVVTGTFGGVDFLHSVTGEVSDKLTQNELQQLENTLENEKRNDTSKL 315  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                                               L+ ++P   dGl    +  k  
  gi|3995136   316 R--------------------------DLLDKIP---DGLIGGDKKSKLN 336  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                    +  E +n+ q+ + +v     p   t                  ++ ++
  gi|3995136   337 -EIEENNNAAQMDQISVSP-REPEEFTR--------------QIQQVFGQ 370  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   i P++EF D + ++i   +e iP L  +lE++ E L  F+   +APF+ P
  gi|3995136   371 IMPVIEFHDELLKTISEKLENIPILPQVLEQLEEQLSMFVFTQIAPFILP 420  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   +i q+ + L  Gss +ie+s n+q   + + rC+dPtHsmLsKDHFtn+L
  gi|3995136   421 VIRQIKNELMTGSSEIIESSKNEQHIVFEDDRCTDPTHSMLSKDHFTNIL 470  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAardE
                   n  AG  a+ +v +vvP ++ Aw+   + +d  ln i+ +v HHPA+rd 
  gi|3995136   471 NEIAGQTASKVVGWVVPQLMEAWDDDNMDIDRLLNRIIYgVLHHPAQRDM 520  

                   ....evEihrkmfetvkkWirEtkn..rhelnslLssEsvKeghnHvlad
                   ++++  E +r +f  +++W +   ++ + ++++ Ls + v +g+nH   +
  gi|3995136   521 gedgAQEGRRLIFRSIEEWWNHMSEdaKDDYRQKLSRDGVENGQNHKEGN 570  

                   qssdssrsvsagsh.....tsnGadgGHGkvaGslWskikkr<-*
                   +  +     + g h++ +++++  d   G +aG++   + +    
  gi|3995136   571 DTGHGC-CKPLGMHknfkeGGTMEDRIAGAAAGAILGGLTSG    611  

gi|258564130|ref|XP_002582810.1|: domain 1 of 1, from 1 to 606: score 563.5, E = 2.4e-166
                   *->magLrigwgsvLLvl..avvLivLPdkAAAFGAGniPsiAqvEGknw
                      ma     w+   L++++++++++   +  AFGAGni s+ ++EG+nw
  gi|2585641     1    MA-----WSTSTLIAttCLLVLIFAHPTVAFGAGNIASLSRIEGQNW 42   

                   RHGDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLK
                   RHGDiEDvL t+A  +  +G+K+  + v+RvYFGnWLRDYsqA+DvG +K
  gi|2585641    43 RHGDIEDVLLTLAMARvagGRKFSKLDVQRVYFGNWLRDYSQAIDVGTVK 92   

                   GvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPE
                    v+A  iR++            WvL F++fGY t EFEvt ERLG Y P 
  gi|2585641    93 YVSAEAIRLM-----------LWVLGFMSFGYGTGEFEVTTERLGTYQPT 131  

                   EHiDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnEsla
                   EHiDnP+gYA+++DAR++D RLRGPvd + EL iDpr+ +          
  gi|2585641   132 EHIDNPLGYAEGDDARRYDRRLRGPVDAnLELSIDPRTDV---------- 171  

                   yqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqA
                      G  atsAG +r  + R+i  GR Y       G  s+L EALR LG  
  gi|2585641   172 ---GI-ATSAGLLRSIFGRCIELGRSYG----RSGDKSELHEALRLLGTG 213  

                   LHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnn
                   LHclED++AHsn+ EL Lie+     G + vFpHvG +t i+l       
  gi|2585641   214 LHCLEDYAAHSNFTELCLIEM-----GEQYVFPHVGRQTMIQL----PGT 254  

                   GkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqasks
                    + vyP+vtGtFG+vDFLHsv+GE  D  tqsE++     L++  ++s+s
  gi|2585641   255 QRPVYPIVTGTFGGVDFLHSVMGEFSDKATQSEIQ----SLEGVMEQSQS 300  

                   sgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg.vGdGlAstARsL
                    g  +s    +l                  L++++P+++  G     +  
  gi|2585641   301 EGSSKS----FL----------------QELLAKIPSdIFGGEDNSGKMD 330  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   + +s+Aq qq s+       n           p  p     +   D vk 
  gi|2585641   331 EFQSNAQAQQQSH------PNI---------SPREPE--EWALYLDNVK- 362  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    ++iYPiLE+ D ++++i   ieK+P +  L+E+i   + +F+ +++AP+
  gi|2585641   363 -AQIYPILEWHDNLMKTISEAIEKLPMISDLIEQIQNEINVFVFSVIAPY 411  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   + P+i+qv   L  Gss +i++s ++q   +n+  C+dPtHsmLsKDHF+
  gi|2585641   412 IIPVINQVKSELETGSSEVIQSSKQQQHNIFNDDYCTDPTHSMLSKDHFS 461  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa
                   nvLn  AG+va  +v + vP i+ Aw+   + ++  l  i+++vFHHPA 
  gi|2585641   462 NVLNEPAGKVAQEVVRWAVPQIMQAWDDDYIDINRTLTRIIHgVFHHPAY 511  

                   rdE....evEihrkmfetvkkWirEt..knrhelnslLssEsvKeghnHv
                   rd +++++ +i+  mf  v+kW  E++++ +  l+  Ls E +++g nH 
  gi|2585641   512 RDYgedgQADIRGLMFGAVEKWWSEQggRGQDSLRAQLSREGIRNGDNHK 561  

                   ..ladqssdssrsvsagsh...tsnGadgGHGkvaGslWskikkr<-*
                   ++  d  +  ++ ++ + h+++ s+G     G  +Gs  s+       
  gi|2585641   562 pgVRDTGHGCGKPLALPKHkskKSSGIPNVLGGLSGSGRSQDADE    606  

gi|85116042|ref|XP_964984.1|: domain 1 of 1, from 1 to 598: score 557.4, E = 1.7e-164
                   *->magLrigwgsvLLvlavvLivL.PdkAAAFGAGniPsiAqvEGknwR
                      ma  ++       vl  ++i L  ++A AFGAGni  i ++EG+nwR
  gi|8511604     1    MATFKPYP----FVLGFLVIYLfASPALAFGAGNIAGISKIEGQNWR 43   

                   HGDiEDvLKtvAF...ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKG
                   HGDiED L  +   + + Gk +  + v RvYFGnWLRDYsqA+DvG +K 
  gi|8511604    44 HGDIEDALLKIVMaraMGGKTFDKLSVSRVYFGNWLRDYSQAIDVGTVKA 93   

                   vnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEE
                   v+A  iR++             vL Fl+fGY   EFEvt +RLG+YRPE+
  gi|8511604    94 VSAEAIRLL-----------LCVLGFLTFGYGSREFEVTADRLGCYRPED 132  

                   HiDnPkgYADikDARkfDaRLRGPvdPr.ELEiDprsGmKnYiAnEslay
                   HiDnPk+YAD+ DAR++D+RLRGPvd ++EL iDp++GmKnYiAnE    
  gi|8511604   133 HIDNPKNYADNVDARDYDPRLRGPVDEEtELAIDPETGMKNYIANEN--- 179  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                     G    sA  vr  + ++i  GR Y    ++     +L EALR +G  L
  gi|8511604   180 -IGI-MSSAEHVRKLFSKCIRLGRSY----KETNDKTELYEALRLMGTGL 223  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED+ AHsnY ELaLie+     G rdvFpHvG dt++ +        
  gi|8511604   224 HCLEDYLAHSNYTELALIEM-----GERDVFPHVGRDTKLRI----PGAR 264  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                   ++vyP+vtGtFG+vDFLHsv GE  D  tqsE+++++  Lka      + 
  gi|8511604   265 HSVYPVVTGTFGGVDFLHSVTGELSDKVTQSEIEDLEGTLKA------GR 308  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg..vGdGlAstARsL
                    G    +  ll                  L+  +P + +G     +  ++
  gi|8511604   309 NG----DTSLL----------------RDLLDMIPNglIGGDKKNKIDEI 338  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   +  +a    +n+    r+                              ++
  gi|8511604   339 QENAANSQLENMSVSPREPEEF---------------------TVYVQQV 367  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    +++ P++EF D +  +i   ieKiP L  ++E++ E L  F+  ++AP 
  gi|8511604   368 YRQVMPVIEFHDDLLQTISKAIEKIPVLPKIIEQLEEQLSLFVFQIIAPV 417  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   + P+idqv + L  Gs+ +i++s n+ql  + +  C+dPtHsmL+KDHF+
  gi|8511604   418 IIPLIDQVKNELATGSTEIINSSKNEQLVVFDDDSCTDPTHSMLAKDHFS 467  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa
                   n+Ln  AGR a+ +v +vvP ++ Aw+  G  vd  ln i+ ++ HHPA+
  gi|8511604   468 NILNEVAGRTASKVVSWVVPQLMDAWDDDGANVDRLLNRIIYgILHHPAQ 517  

                   rdE....evEihrkmfetvkkWirE..tknrhelnslLssEsvKeghnHv
                   rd ++++  E ++ mf  v++W ++ ++  r+e+++ Ls   v +g nH 
  gi|8511604   518 RDMgedgAQEGRQMMFSSVEEWWNDlgEDAREEYRQKLSRNGVLNGENH- 566  

                   ladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                         +++  v   +h+    +g H        + ++ r   
  gi|8511604   567 ------KEG--VQDCGHGCGKPLGMHKNFKNEAPETMEDR    598  

gi|121709055|ref|XP_001272292.1|: domain 1 of 1, from 1 to 607: score 548.8, E = 6.5e-162
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m      +g    +  ++++ L +k  AFGAGni si +vEG+nwRH
  gi|1217090     1    MRVSFQNFG----ISILLVLLLSGKVHAFGAGNIASISRVEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED+L t+   +  +G+K+  + v+RvYFGnWLRDYsqAvDvG LK v
  gi|1217090    44 GDIEDTLLTLFLARvagGRKFSKLDVQRVYFGNWLRDYSQAVDVGTLKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +   iRi+           +WvL Fl+fGY t+EFEvt ERLG+Y P EH
  gi|1217090    94 STEAIRIL-----------IWVLGFLSFGYGTKEFEVTTERLGCYEPTEH 132  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnP+gYAD++DAR++D+RLRGP+d+ rEL iDp +G+KnYiAnE     
  gi|1217090   133 IDNPLGYADGEDARRYDSRLRGPIDeERELSIDPSTGLKNYIANEN---- 178  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                                     i  GR Y         ++DL EALR LG  LH
  gi|1217090   179 ------------------IGIGRRYARSRN----DEDLHEALRLLGTGLH 206  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Liel     G + +FpHvG +t++++         
  gi|1217090   207 CLEDYAAHSNYTELSLIEL-----GESIIFPHVGRNTKLEV----NSVQD 247  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDF HsvLGE  D  tqsEv+ ++  +   +  + s +
  gi|1217090   248 YVYPIVTGTFGGVDFFHSVLGELSDKTTQSEVQCLEGVINESQNGTPSQS 297  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           +                   L+s++P   +Gl    R+ +A 
  gi|1217090   298 F-------IQ-----------------DLLSKIP---EGLIGD-RDNQAG 319  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                        +  ++   + n             p  p         D v   ++
  gi|1217090   320 KMDEFKTKAEDAKAHNQEI---------SPREPE--EWTRYLDDVH--RQ 356  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   +YP+LE+ D +++sin  ieKiP L  L+++  E + +F+ ++LAP++ P
  gi|1217090   357 VYPVLEWHDNLIKSINRAIEKIPVLPELIDQFQEQINVFVFAVLAPYILP 406  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii qv   L+ Gss +i++s  +q   + +    +PtHsmLsKDHF+nvL
  gi|1217090   407 IITQVKTELQTGSSEIIQSSQAQQHIVFDDDDSSNPTHSMLSKDHFSNVL 456  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AGR+a+ +v++ vP ++  w+n  + vd  +  i+ +vFHHPA+r+ 
  gi|1217090   457 NEPAGRIASQVVKWTVPQLMECWDNEDIDVDRTIDRIVTgVFHHPALRqy 506  

                   ..dEevEihrkmfetvkkWi..rEtknrhelnslLssEsvKeghnH....
                   ++d   + +r mf tv++W +++++ +++ l++ Ls + v eg+nH+++ 
  gi|1217090   507 geDGASDARRIMFGTVEEWWsgKDEAEKESLREQLSRDGVFEGKNHkegv 556  

                   ....vladqssdssrsvsagshtsnGadgGHGkva......GslWskikk
                   ++++ + +++   +r  s +  + n    G G+ a++  ++Gsl   + +
  gi|1217090   557 hdsgHGCGKPLTLHRGQSQPNNGYNSDTSGLGRIAseaaggGSLGGLVGR 606  

                   r<-*
                       
  gi|1217090   607 L    607  

gi|289617909|emb|CBI55486.1|: domain 1 of 1, from 1 to 610: score 543.8, E = 2.1e-160
                   *->magLrigwgsvLLvlavvLivL.PdkAAAFGAGniPsiAqvEGknwR
                      ma  ++       vl  ++i L  ++A AFGAGni  i ++EG+nwR
  gi|2896179     1    MASFKPYP----FVLGFLVIYLfASPALAFGAGNIAGISKIEGQNWR 43   

                   HGDiEDvLKtvAF...ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKG
                   HGDiED L  +   + + Gk +  + v RvYFGnWLRDYsqA+DvG +K 
  gi|2896179    44 HGDIEDALLKIVMaraMGGKTFDKLSVSRVYFGNWLRDYSQAIDVGTVKA 93   

                   vnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEE
                   v+A  iR++             +L Fl+fGY   EFEvt +RLG+YRPE+
  gi|2896179    94 VSAEAIRLL-----------LCILGFLTFGYGSREFEVTADRLGCYRPED 132  

                   HiDnPkgYADikDARkfDaRLRGPvdPr.ELEiDprsGmKnYiAnEslay
                   HiDnPk+YAD+ DAR++D+RLRGP+d + EL iDp++GmKnYiAnE    
  gi|2896179   133 HIDNPKNYADNVDARDYDPRLRGPIDEGvELAIDPETGMKNYIANEN--- 179  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                     G    sA  vr  + ++i   R Y    +      +L EALR +G  L
  gi|2896179   180 -LGI-MSSAEHVRNLFSKCIRLARSY----KDTNDKTELYEALRLMGTGL 223  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED+ AHsnY ELaLie+     G rd+FpHvG dt++ +        
  gi|2896179   224 HCLEDYLAHSNYTELALIEM-----GERDIFPHVGRDTKLRI----PGAR 264  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                   ++vyP+vtGtFG+vDFLHsv GE  D  tqsE+++++  L+a        
  gi|2896179   265 HSVYPIVTGTFGGVDFLHSVTGELSDKMTQSEIEDLEGTLQA-------- 306  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPg..vGdGlAstARsL
                    G +s +  ll                  L+ ++P + +G     +  ++
  gi|2896179   307 -GRNS-DTSLL----------------RDLLDKIPDglIGGDKKNQLDEI 338  

                   kAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkt
                   +  +a    +n+    r+                              ++
  gi|2896179   339 QENAANSQLENMSVSPREPEEF---------------------TLYVQQV 367  

                   akkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPF
                    +++ P++EF D +  +i   ieKiP L  ++E++ E L  F+  ++AP 
  gi|2896179   368 FRQVMPVIEFHDDLLQTISKAIEKIPVLPKIIEQLEEQLSLFVFQIIAPV 417  

                   vRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFt
                   + P+idq+ + L  G++ +i++s n+q   +n+   +dPtHsmLsKDHF+
  gi|2896179   418 IIPLIDQIKNELATGATEIINSSKNEQHVVFNDDSSTDPTHSMLSKDHFS 467  

                   nvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAa
                   n+Ln  AGR a+ +v +vvP ++ Aw+n  v vd  ln i+ ++ HHPA+
  gi|2896179   468 NILNEIAGRTASRVVSWVVPQLMDAWDNDSVDVDRLLNRIIYgILHHPAQ 517  

                   rd...EevEihrkm.fetvkkWirE..tknrhelnslLssEsvKeghnHv
                   rd +++  E  r+m f  v++W ++ ++  r+e++  Ls E v +g nH 
  gi|2896179   518 RDmgeDGAEEGRHMlFSSVEEWWNDlgEDAREEYRYKLSREGVLNGENHR 567  

                   ladqssdssrsvsagsh...tsnGadgGHGkvaGslWskikkr<-*
                      q   ++   + g h++      +    k a +  ++i      
  gi|2896179   568 EGVQDCGHGCGKPLGMHknfKNEAPETMEDKIAAAAADRIMGG    610  

gi|71014539|ref|XP_758725.1|: domain 1 of 1, from 237 to 823: score 540.0, E = 2.9e-159
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                        g r  +  +L +l + L  +P+ A AFGAGniPs A +EGk +RH
  gi|7101453   237    WLGGRFFFVVMLSMLIIALSSVPG-AYAFGAGNIPSFAYMEGKAFRH 282  

                   GDiEDvLKtv......AFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsL
                   GDiED+L ++ ++ ++      K+  + ++R+YFGnWLRDYsqA+Dv +L
  gi|7101453   283 GDIEDILEELfkkaggSLFGSSKFSGLDIKRTYFGNWLRDYSQAMDVAAL 332  

                   KGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRP
                   + ++   i  +           v vL Fla+GYAt+EF vt+ERLGvY P
  gi|7101453   333 QKMSKQAILNL-----------VMVLGFLAHGYATAEFQVTDERLGVYLP 371  

                   EEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEsla
                   EEH+DnPkgYAD+kDAR++D+RLR P+dP+ELEiDprsGmKnY+AnE   
  gi|7101453   372 EEHLDNPKGYADGKDAREYDPRLREPIDPQELEIDPRSGMKNYLANEN-- 419  

                   yqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqA
                     g W  t  G vr  l   i  GR     +r+ G++ DL EA R LGqA
  gi|7101453   420 --GRW-RTGSGLVRRTLTQVIEMGR----RARESGRDADLYEAYRLLGQA 462  

                   LHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnn
                   LH+lEDF+AHsn+ ELaL  l     G+++vF HvG + ++         
  gi|7101453   463 LHTLEDFPAHSNWTELALHRL-----GHHNVFLHVGDNVKVRA-----PD 502  

                   GkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqasks
                   G ++ P+vtGtFG+ DF+Hs LGEA DH   + + +++ A+  A++  +s
  gi|7101453   503 GTQIAPIVTGTFGSADFIHSLLGEAQDHLSEASISDLNKAMDDAKR--QS 550  

                   sgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLk
                   sg     +R  +                +++++++Pg G    s  R+L+
  gi|7101453   551 SGD----NRSPV-------------QSLLGMLAKVPGGGGSNVS--RDLE 581  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                     s     + ++                           msP+    ++ 
  gi|7101453   582 DVSRGPVSDPAN---------------------------MSPQ----EMY 600  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   + ++ iLE RD+iv+ i  +ieKiPGL sL+Ek+   L +F+  L+ P+ 
  gi|7101453   601 ANLWKILELRDRIVKGIEGTIEKIPGLSSLIEKLFNELNIFVFTLIEPYA 650  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                   +Pi++q  ++LK Gs ++i+   ++q+E + nP   dPtHsmLsKDHF  
  gi|7101453   651 KPIMQQGMNALKLGSGAVINK--QEQFEVFDNPNASDPTHSMLSKDHFGL 698  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAar.
                   +Ln  AG va  iv   v Ri+ Aw+   +    v  + L    HP   +
  gi|7101453   699 ILNEVAGNVAKIIVRNTVTRIVKAWDDRSMDPARVADECLAPMVHPYWIg 748  

                   dEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssd
                   ++   ++++m e v  W+r      e+   Ls  sv+++ n    + + +
  gi|7101453   749 NDAAPVQKEMMEYVAGWARNH--STEIGR-LSKQSVRNHTNTRSGKAEPH 795  

                   ssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    +    +      G+  G G  + +  s   ++   
  gi|7101453   796 TH----GNDQPNMGSFMG-GANSQAAHSFQSSH    823  

gi|171687657|ref|XP_001908769.1|: domain 1 of 1, from 1 to 600: score 538.3, E = 9.4e-159
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+ r     +L v+ +   v P    AFGAGni  i  +EG+nwRH
  gi|1716876     1    MAYSREYPTILLGVILLFWFVKP--TLAFGAGNIAGISSIEGQNWRH 45   

                   GDiEDvLKtvAF...ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L  v   + + Gk++  +mv RvYFGnWLRDYsqA+DvG +K v
  gi|1716876    46 GDIEDALLKVMMaraVGGKRFDKLMVSRVYFGNWLRDYSQAIDVGTVKSV 95   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++             vL F++fGY  +EFEvt +RLG+YRPE+H
  gi|1716876    96 SAEAIRLL-----------LCVLGFITFGYGSKEFEVTADRLGCYRPEDH 134  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnPk+YA+++DAR++   LRGPv++  EL iDp++GmKnYiAnE     
  gi|1716876   135 IDNPKDYAENEDARQYHRALRGPVNeEVELAIDPETGMKNYIANEN---- 180  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA   r  +  ai  GR Y       G  +DL E LR +G  LH
  gi|1716876   181 IGI-MTSAAHCRKLFTDAIELGRRYG----RSGNKDDLYECLRLIGTGLH 225  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED+ AHsnY ELaLie+     G +d+FpHvG +t+i l         
  gi|1716876   226 CLEDYFAHSNYIELALIEM-----GEQDIFPHVGRNTKISL----EGAND 266  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv GE  D   qsE+++++  L   eq ++s  
  gi|1716876   267 EVYPIVTGTFGGVDFLHSVTGEVSDKLIQSEIQDLENTL---EQSKNSDL 313  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           +l                  L+ ++P   dGl    +  k  
  gi|1716876   314 S-------YL----------------RELLDKIP---DGLIGGDKKNKVN 337  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnF..Dpvkta
                    + q+  n+ q+ + ++                       +F++    + 
  gi|1716876   338 -EIQDNANAAQMEQTSISP-----------------KETEEFtrQVQDIF 369  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   ++i P +E+ D + +si   +++iP L  ++E++ E L  F+  ++APFv
  gi|1716876   370 RQIMPAIEYHDDLLKSISEAVSRIPILPKIIEQLEEQLSLFVFQVIAPFV 419  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    P+i+q+ + L  G++ +ie+s n+q   + +    dPtHsmLsKDHFtn
  gi|1716876   420 IPVIEQIKNELATGATEIIESSKNEQHIVFEDDDASDPTHSMLSKDHFTN 469  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar
                   +Ln  AGR a+ +v + vP ++ A +  Gv vd vln i+ +v HHPA+r
  gi|1716876   470 ILNEVAGRAASKVVSWSVPQLMEAIDDEGVDVDRVLNKIIYgVLHHPAQR 519  

                   ....dEevEihrkmfetvkkWirEt..knrhelnslLssEsvKeghnHvl
                   ++++d   E +r ++  v++W ++ ++ ++++++  Ls E v +g nH  
  gi|1716876   520 ntgpDGADEGRRLIYGIVEEWWNDMgrGQQEDYRRKLSREGVENGENHRE 569  

                   adqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    ++   ++         + G +      a +  + ++ r   
  gi|1716876   570 GEKDCGHG--------CGGGGLKVKKNYANAAPETMEDR    600  

gi|156053868|ref|XP_001592860.1|: domain 1 of 1, from 1 to 595: score 538.3, E = 9.6e-159
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                        g  +  g v     +   v P               +   + wRH
  gi|1560538     1    -MGFGVVEGLVGFFTPIWTSVDPHYR-----------VNTYAQAWRH 35   

                   GDiEDvLKtvAF...ikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED+L  +  ++   GkK+  mmv RvYFGnWLRDYsqA+DvG +K v
  gi|1560538    36 GDIEDTLLSLVMsraCGGKKFDKMMVARVYFGNWLRDYSQAIDVGTVKYV 85   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iRi+            WvL F++fGY t+EFEvt  RLG+YRPE+H
  gi|1560538    86 SAEAIRIL-----------LWVLGFMTFGYGTKEFEVTAQRLGCYRPEDH 124  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnPk+YAD+ DA ++D RLRGPvd+  EL iDp++GmKnYiAnE     
  gi|1560538   125 IDNPKDYADNLDASQYDHRLRGPVDeEVELAIDPETGMKNYIANEH---- 170  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsD.LCEALRCLGqAL
                    G   tsA  vr  +  +i  GR Y     g+ k +D+L EALR LG  L
  gi|1560538   171 AGI-MTSAFHVRKLFHESIRLGRSY-----GRSKNKDeLYEALRLLGTGL 214  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   HclED+sAHsnY ELaLie+     G +dvFpHvG  t+i+l        
  gi|1560538   215 HCLEDYSAHSNYTELALIEM-----GEHDVFPHVGRRTQIEL----PGVQ 255  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskss
                   + vyP++tGtFG+vDFLHsv+GE  D  tqsE++ ++  +      +++s
  gi|1560538   256 HPVYPIITGTFGGVDFLHSVMGEFDDKATQSEIQTLEGTM------EEGS 299  

                   gGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkA
                    G +s    ll              D +s v      G   A +A +L+A
  gi|1560538   300 QGNSS----LL-------------KDLLSSVPSGLFGGKDQAGKADELQA 332  

                   .asaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                   +asaAq  q        ++ +                          ++a
  gi|1560538   333 nASAAQQSQEHVSPKDPEAFT----------------------LQMQQVA 360  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   k+iYPi+ + D i+  i   ieKiP L +L+E i + + +F+ +LLAPFv
  gi|1560538   361 KEIYPIIQWHDEIMQQIREAIEKIPILPALIENIEDQINIFVFSLLAPFV 410  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    Pii+q+   L  Gss +i++s ++ql  + +    dPtHsmLsKDHF+n
  gi|1560538   411 LPIINQIKTELNTGSSEVIQSSKDKQLIVFHDDYSSDPTHSMLSKDHFSN 460  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar
                   +Ln CAG++a+ ++++vvP ++  w+   +  +  +n i+++vFHHPA+r
  gi|1560538   461 ILNECAGKIASQVLKWVVPQLISCWDDERIDPERTINRIIHgVFHHPALR 510  

                   ....dEevEihrkmfetvkkWirEt..knrhelnslLssEsvKeghnHvl
                     ++d   + ++ mf  v++W + +++ +++e++  Ls E v +g nH l
  gi|1560538   511 yygeDGASDGRQLMFRVVEEWWHNKdgDEQEEFRRKLSREGVEDGENH-L 559  

                   adqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   ++ ++  +     g+      +g     +  l +++      
  gi|1560538   560 EGVHDTGH---GCGAPLKMSKQGPMMSSSNPLANEMMGG    595  

gi|169851344|ref|XP_001832362.1|: domain 1 of 1, from 1 to 618: score 537.0, E = 2.4e-158
                   *->magLrigwgsvLLvlavvLivLPdk..AAAFGAGniPsiAqvEGknw
                      m+     +  +L  l  vL+   ++++  AFGAGniPs A +EG+ +
  gi|1698513     1    MSRSYSSSTYFLPALLFVLVFCLSRngVYAFGAGNIPSFAYMEGRAF 47   

                   RHGDiEDvLKtvA...........Fi.kGkKWttmmvgRvYFGnWLRDYs
                   RHGDiEDvL ++A++  ++    + i+kG+K+ ++  +RvYFGnWLRDYs
  gi|1698513    48 RHGDIEDVLDDLAkgaaggfalasLIgKGRKFNALDKKRVYFGNWLRDYS 97   

                   qAvDvGsLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtE
                   qA+D+  LK +   ti  +             vL F+a+GYAt+EFE+tE
  gi|1698513    98 QAIDIATLKKMPQQTIINL-----------LMVLGFMAHGYATNEFEITE 136  

                   ERLGvYRPEEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKn
                   ERLG+Y P EHiDnPkgY D++D R++ + LR P+dPrELEiDpr+GmKn
  gi|1698513   137 ERLGCYLPVEHIDNPKGYGDGEDPRQYHPGLRPPIDPRELEIDPRTGMKN 186  

                   YiAnEslayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCE
                   YiAnE     g W  ts  Yvr  l+ +iH GRL     r +G+ +D  E
  gi|1698513   187 YIANED----GHW-DTSKAYVRRILENCIHHGRLH----RSRGQKQDEYE 227  

                   ALRCLGqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadtein
                   A R LG ALH+lED+sAHsn+CELaL+ +     Gy++vF HvG + +++
  gi|1698513   228 AFRLLGTALHTLEDYSAHSNFCELALVGM-----GYNEVFTHVGDNVRVQ 272  

                   lrndtrnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALk
                          nGk v P+vtGtFG+ DF Hs LG A D    + v +++  L 
  gi|1698513   273 A-----PNGKWVAPIVTGTFGSDDFFHSLLGGASDSLSEASVSDLNRELD 317  

                   aAeqaskssgGGdsrqRGlllfglnlgGsgssgtDFi.sLvsqlPgvGdG
                    A  + +    G +             G   + +D ++ L   +P  G G
  gi|1698513   318 KARSKAQTQTRGPG-------------GPPCDPADALrDLFFAIP--GGG 352  

                   lAstARsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGms
                        R+L         +n ++  ++ +              g     ms
  gi|1698513   353 GSEMSRDL---------DNIQRIRAGPAAG------------GKNPDEMS 381  

                   PnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF
                   P     +  + ++ +L FRD +++ i  +ieKiPGL sLl+ki + + +F
  gi|1698513   382 PK----ELHATLWQVLLFRDSVMKKISKTIEKIPGLGSLLDKITDSISVF 427  

                   iLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHs
                   +   + PF++Pi++  ++ L   s+ +++   + q+E +n+Pr  dPtHs
  gi|1698513   428 VFTTIEPFLKPILKTATEGLHTVSAEVVDK--HDQYEVFNDPRASDPTHS 475  

                   mLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr
                    LsKDHF  +Ln  AG+ a  iv   vP i+ Aw+   v v+  ++++ +
  gi|1698513   476 FLSKDHFNLILNEPAGKLAQVIVINTVPLIIKAWDDASVNVNQTIEEVTQ 525  

                   vFHHPAardEevEihrkmfetvkkWirEtknrhelnslLssEsvKeghnH
                      HP  ++ +  ++r+m + +++W++  +n+h++ + Ls  sv+++   
  gi|1698513   526 CLFHPDFHNPNSKVQREMLQCMRDWVEKLPNKHQIIQRLSKQSVRNHEHI 575  

                   vladq...ssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                     a++++++ +++    + +h    ++ G  +     +s  ++    
  gi|1698513   576 RAAGDggpPASQGSFAEGQAHQFQQTLQGYAQNIPG-FSAAQSM    618  

gi|242206537|ref|XP_002469124.1|: domain 1 of 1, from 2 to 596: score 521.3, E = 1.2e-153
                   *->magLrigwgsvLLvlavvLivLPdkAA.AFGAGniPsiAqvEGknwR
                                +L vl++++  + ++   AFGAGniP  A +EGk +R
  gi|2422065     2    ----------LLTVLCILVFCVSGNGVyAFGAGNIPGFAYLEGKAFR 38   

                   HGDiEDvLKtvA.....FikGk.......KWttmmvgRvYFGnWLRDYsq
                   HGDiED+L +vA++ ++F  G   +++++K+  + ++RvYFGnWLRDYsq
  gi|2422065    39 HGDIEDTLSEVAkraggFALGAligrggsKFGGLDIKRVYFGNWLRDYSQ 88   

                   AvDvGsLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEE
                   AvDv  L   +  ti  +             vL F++ GYAteEFEvt E
  gi|2422065    89 AVDVAGLSKLQFQTIVNL-----------CMVLGFMSLGYATEEFEVTPE 127  

                   RLGvYRPEEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnY
                   RLGvY P EHiDnPkgY D  DA ++ ++LRGPvdPrELEiD ++GmKnY
  gi|2422065   128 RLGVYLPTEHIDNPKGYPD--DAQRYHPKLRGPVDPRELEIDHHTGMKNY 175  

                   iAnEslayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEA
                   iAnE     g W  ts   vr  l+ +i  GR Y    r  G   D  EA
  gi|2422065   176 IANEH----GHW-DTSKALVRRTLQQCIQIGRQY----RSTGNKADEYEA 216  

                   LRCLGqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinl
                    R LGqALH+lEDF+AHsn+CELaL+ l     GyrdvF HvG + +i+ 
  gi|2422065   217 YRLLGQALHTLEDFAAHSNFCELALVSL-----GYRDVFVHVGDQVRIQA 261  

                   rndtrnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsE.vdEmdlALk
                          G+ v PLvtGtFG+ DF+Hs LG    H   + +v +++  L 
  gi|2422065   262 -----PDGRWVAPLVTGTFGSSDFIHSLLGGKCYHASSTAsVVDLNAELD 306  

                   aAeqaskssgGGdsrqRGlllfglnlgGsgssgtDFi.sLvsqlPgvGdG
                    A  +s s +  ++             Gs+ s +D ++sL+ +lP     
  gi|2422065   307 RARSKSASQSR-SG-----P-------GSSRSPADLLrSLLFKLPDTDGS 343  

                   lAstARsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGms
                        R+L+        +  r  +++ + +           pg   P   
  gi|2422065   344 GGEMERELEGV------ERIR--AQGYGAQ-----------PGSRRP--- 371  

                   PnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF
                    +  p +  + ++ +L FRD +++ i  +ieKiPGLEsL+E+isE + +F
  gi|2422065   372 EDMNPQELHAVLWQVLRFRDNVMKKITMVIEKIPGLESLVERISESISVF 421  

                   iLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHs
                   +   L PF+RP+++  + +L   ss +i+   + q+E +n+Pr  dPtHs
  gi|2422065   422 VFTTLEPFLRPVMKDATSALAAASSEVINK--HDQYEVFNDPRASDPTHS 469  

                   mLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr
                    LsKDHF  +Ln  AG     i+ Y + R++ Aw+ P +    v  DiL+
  gi|2422065   470 FLSKDHFNLILNEPAGHLGKIILIYATTRVVKAWDDPSINMLYVTDDILH 519  

                   vFHHPAardEevEihrkmfetvkkWirEtknrh.elnslLssEsvKeghn
                      HP     +  i+++m e ++ W++   ++++++   L+  sv+++ n
  gi|2422065   520 CMFHPDFNTRNSPIQHEMMEYMRSWVQGLGHQQpKVLRRLTKQSVRNHLN 569  

                   HvladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                     l ++   s                GHG va     ++++    
  gi|2422065   570 MRLGSEGAAST---------------GHGTVAQTAGMEVQND    596  

gi|39960084|ref|XP_364543.1|: domain 1 of 1, from 1 to 611: score 509.4, E = 4.7e-150
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         ++     + L+  v+L+   ++A AFGAGni s   +EG nwRH
  gi|3996008     1    ---MMDSRTNFWLIGIVLLVCWASPAYAFGAGNISSKSPIEGINWRH 44   

                   GDiEDvLKtvAFi.....kGkKWttmmvgRvYFGnWLRDYsqAvDvGsLK
                   GDiED L  +   +  ++k kK+  m v RvYFGnWLRDYsqAvD G +K
  gi|3996008    45 GDIEDALLGIIMAraldkKSKKFNKMAVMRVYFGNWLRDYSQAVDLGTIK 94   

                   GvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPE
                    v+   iR++           v +L+F+ fG+  +EFEvt ERLG+YRPE
  gi|3996008    95 NVSYEAIRLV-----------VAILAFMNFGFGSKEFEVTPERLGCYRPE 133  

                   EHiDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEsla
                   EHiD PkgY  ++  +++   LRGPvd+ rEL +Dp sGmKnYiAnE+  
  gi|3996008   134 EHIDSPKGYGGGDNPKRYWEGLRGPVDeERELTVDPDSGMKNYIANER-- 181  

                   yqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqA
                      G   tsAG +r  l R+i  GR         G+++DL E +R +G A
  gi|3996008   182 --AGI-DTSAGLLRNLLGRCIDLGRAHA----RSGRDEDLYESMRLMGTA 224  

                   LHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnn
                   +HclEDF AHsnY ELaLie+     G+rdvFpHvG dt++ +      +
  gi|3996008   225 MHCLEDFFAHSNYVELALIEM-----GHRDVFPHVGRDTKLRI---PGSR 266  

                   GkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqasks
                   G +vyP+vtGtFG vDFLHsv GE  D   q E +E++  L+  +++  s
  gi|3996008   267 G-EVYPIVTGTFGEVDFLHSVAGEVSDKIKQNELQELEELLQDNKKNDTS 315  

                   sgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLk
                             ll                  L   lP    G  s+   + 
  gi|3996008   316 ----------LL----------------KNLFKMLPDSLFGGESQSSKMD 339  

                   AasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvkta
                        q  q   q   +n  v           p      +s  F      
  gi|3996008   340 -----QIEQDCTQAQMNNLEV------RPHREPEEITKWVSNIF------ 372  

                   kkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFv
                   k+i P++E+ D+i++ i   +  iP +  ++E++ + L aF++  LAPF+
  gi|3996008   373 KQIIPVIEWHDRIMKIISDALPSIPVIPKIIEQLEDQLNAFVMMQLAPFI 422  

                   RPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtn
                    P+++q+ + +  Gs g++e+s + q+  + + r  dPtHsmLsKDHFtn
  gi|3996008   423 VPVLQQIQNEMNAGSNGIVESSKRDQFVVFDDDRSADPTHSMLSKDHFTN 472  

                   vLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar
                   +Ln  AG+ aa +v++vvP i+ A +   + +   +n i+ +v HHPA+r
  gi|3996008   473 LLNEPAGKTAAEMVKWVVPQIMQAMDDESIDIGRTVNRIIYgVLHHPAQR 522  

                   ....dEevEihrkmfetvkkW..irEtknrhelnslLssEsvKeghnHvl
                   + ++d   E +   f  +++W +     +++++   Ls + v+++ nH  
  gi|3996008   523 slghDGANEGREIFFRSIEQWwgCMGPDQQRDYLRRLSRDGVRNHENHKE 572  

                   adqssdssrsvsagshtsnGadgGHG.kvaGslWs.kikkr<-*
                    +    ++      +h  +   +G G+k     W++ki ++   
  gi|3996008   573 GEYDTGHN--NGCLGHLDTSHIHGDGkKKKKDTWEdKIATQ    611  

gi|154279436|ref|XP_001540531.1|: domain 1 of 1, from 1 to 617: score 500.9, E = 1.6e-147
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         + + +v+ +    +  AFGAGni s+ ++EG+nwRH
  gi|1542794     1    MAW---STTTTVALTCVLFLLFTRPVHAFGAGNIASVSKIEGQNWRH 44   

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                   GDiED + t+   +            +    L     A+D+G LK v+A 
  gi|1542794    45 GDIEDAILTLMMARFGGREEFFKTPGFSVFILEIGFRALDIGTLKYVSAE 94   

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                   tiR++            WvL  ++fGY t EFEvt +R+G+Y P EHiDn
  gi|1542794    95 TIRLL-----------LWVLGIMTFGYGTGEFEVTLDRIGCYQPTEHIDN 133  

                   PkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayqgGW
                   P+gY +++DAR++   LRGPvd+ rEL +D r+G+KnYiA E      G 
  gi|1542794   134 PLGYGEGQDARRYYRHLRGPVDeERELGVDARTGLKNYIASED----LGI 179  

                   natsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclE
                      sA  +r  +  +i  GR Y   sr + ++ DL EALR LG  LH+lE
  gi|1542794   180 -DNSASLLRKVFGNCIELGRRY---SRSR-RDADLYEALRLLGTGLHTLE 224  

                   DFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvy
                   D+ AHsnY EL Liel     G  +vFpHvG ++ i+l    +    +vy
  gi|1542794   225 DYLAHSNYTELSLIEL-----GETNVFPHVGRNAMIQL----QGARNSVY 265  

                   PLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGd
                   P+vtGtFG+vDFLHsv+GE  D  tqsE++ ++  ++  e ++       
  gi|1542794   266 PIVTGTFGGVDFLHSVMGEISDKATQSEIQNLEGMIEESENQKP------ 309  

                   srqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaA
                     q G+l                  L+ ++P   +Gl     + +   + 
  gi|1542794   310 --QEGFL----------------QVLLDKIP---EGLLGSEDNTEKMNEF 338  

                   qEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakkiYP
                   q    s ++  +n+             p      m        + ++++P
  gi|1542794   339 QSNAESTKQRNENISP---------REPEQWATYMN------DVQQQMFP 373  

                   iLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiid
                   +LE+ D +++sinn ieKiP +  L+E++ E +t+F+ +++AP+v Pi++
  gi|1542794   374 LLEWHDNLMKSINNAIEKIPAIPELVEQVQEQITIFVFSVMAPYVLPILK 423  

                   qvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsC
                   qv   L  Gss +i++s + q+  +nn rC+dPtHsmLsKDHF+n+Ln  
  gi|1542794   424 QVKAELEIGSSEVIQSSKEGQFNTFNNDRCTDPTHSMLSKDHFSNLLNEP 473  

                   AGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar....d
                   AG+ a+ +v++vvP i+  w+   + v+  +n i+ +vFHHPA+r+ ++d
  gi|1542794   474 AGKAASEVVKWVVPQIMECWDDESIDVNRTMNRIINgVFHHPALRqygeD 523  

                   EevEihrkmfetvkkWirEtknr..helnslLssEsvKeghnH.......
                      E++r+mf  ++ W +E+ +r++  l++ Ls E v++g nH+++ +++
  gi|1542794   524 GSQEMRRTMFGVIESWWNEQGRRgqDSLRQQLSREGVRNGDNHkpgvhds 573  

                   .vladqss...dssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                   + + +++++ ++++r v++g     G +g  Gk +    s+i+k    
  gi|1542794   574 gHGCGKPMglpNRNRPVPGGVQDLFGLQGLGGKSSMNT-SNIEKM    617  

gi|50557358|ref|XP_506087.1|: domain 1 of 1, from 1 to 691: score 498.6, E = 8.5e-147
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m   +  + s        L  L   A AFGAGniPs   +EGkn+RH
  gi|5055735     1    MKLPILASLSG-------LAGLFTTAHAFGAGNIPSDSSIEGKNFRH 40   

                   GDiEDvLKtvAFi....kGkKWttmmvgRvYFGnWLRDYsqAvDvGsL.K
                   GDiEDvL  +   ++++k +K+  + ++RvYFGnWLRD+sqAvDvG L+ 
  gi|5055735    41 GDIEDVLAGIVIShrggKARKFDGLDIKRVYFGNWLRDFSQAVDVGTLsM 90   

                   GvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPE
                   G nA t+R i           +W +s   fGY t EFEvtEERLGvYR E
  gi|5055735    91 GLNADTVRAI-----------IWLVSMSEFGYGTGEFEVTEERLGVYRAE 129  

                   EHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslay
                   EH+DnPkgY   +DA ++D RLRGPvdPrELEiDp++GmKnYiAnE    
  gi|5055735   130 EHMDNPKGY--PEDAQQYDRRLRGPVDPRELEIDPKTGMKNYIANED--- 174  

                   qgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqAL
                    g W ats  Yvr  l R+i  GR Y  G  g  k s   E LR LG AL
  gi|5055735   175 -GDW-ATSSEYVREQLLRCIKLGRRYIKG--GYKKHSLQHESLRLLGSAL 220  

                   HclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnG
                   H+lEDF+AH+nY EL+L+++     Gy+dv++HvG +t+i l       G
  gi|5055735   221 HTLEDFTAHTNYLELVLRDM-----GYKDVYAHVGNQTRIKL------AG 259  

                   krvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqa.sks
                   k+v+P+vtGtFG+ DFLHs LG A D    s   E     +  ++ +s+ 
  gi|5055735   260 KKVFPVVTGTFGGLDFLHSLLGGAHDSLSESGFTEASANFEKKKKSgSNT 309  

                   sgGGdsrqRGlllfglnl.....gGsgssgtDFisLvsqlPgvGdGlAst
                   s   +s  R l +   ++++ ++g     g+D +  + +l    + +   
  gi|5055735   310 SEFLKSILRKLPIKLPDIpdahgGFRDMTGADLADHLDELQHNVEEYVVH 359  

                   ARsLkAasa.AqEqqnsrqltr.....anvnvfnappgstggppgpgvPG
                    R+     ++ ++    ++++r++++++n+ + + p   +  pp    PG
  gi|5055735   360 QREHDGNDEdCKDCGDTKKKSRtggsgGNAQQGQHPLVLVDQPPFKNTPG 409  

                   ...ms......PnF..........DpvktakkiYPiLEFRDKivRsinnm
                   ++++s+ ++++Pn+++ ++  ++ D  ++ + +YP+LEF+D ++ s+   
  gi|5055735   410 gtnISkvhnndPNYtslesyldnlDVDAVIRAVYPLLEFKDSVMSSLESF 459  

                   i...eKiPGLEsLlEkisEtLtaFiLgLLAPFvRPiidqvskvLKeGssg
                    ++++    L  +   is+ L  F  +++ P + Pi+++v+++L    + 
  gi|5055735   460 FgdsDSSTALGMMASSISDALSSFTNSIINPIINPILEAVTEILHASVTL 509  

                   lieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLnsCAGRvaativqYv
                   l  +  + q++ W n + +dPtHs LsKDHF+  Ln  AG vaa +v+Yv
  gi|5055735   510 L--SYHDDQIDVWINSKSTDPTHSRLSKDHFAAYLNEPAGLVAAEVVKYV 557  

                   vPRilYAwenPGvPvdEvlnDiLrvFHHPAardEevEihrkmfetvkkWi
                   vP ++ Awe P +  + v+ + L++FHHPA+   +  +hr m   v +Wi
  gi|5055735   558 VPFVVEAWEDPSIDPQTVVDEALQTFHHPALA--HTKLHRIMRAEVDRWI 605  

                   rEtknrhelnsl...LssEsvKeghn.................Hvladqs
                   +     +e +++ ++L+s  v +ghn+ ++ + ++ + +++ +H +++++
  gi|5055735   606 QTF-SDEEREHIlegLTSRGVLHGHNnaehldvnnvtyedpfdHTGSEEK 654  

                   sdssrsvsa..gshtsnGadgGHGkvaGslWskikkr<-*
                    +         g     G+  G G  +Gs+  + k +   
  gi|5055735   655 ASTFLDYIDyfGFFNQQGSGSGSGSGSGSMKREHKDK    691  

gi|170099658|ref|XP_001881047.1|: domain 1 of 1, from 1 to 634: score 476.3, E = 4.2e-140
                   *->magLrigwgsvLLvlavvLivLPdkAA.AFGAGniPsiAqvEGknwR
                         +      +LL+  +    L ++  +AFGAGniPs A +EG+ +R
  gi|1700996     1    ---MPRNRTILLLLFFIFAFCLSSNGVhAFGAGNIPSFAYMEGRAFR 44   

                   HGDiEDvLKtvA.......Fik.......GkKWttmmvgRvYFGnWLRDY
                   HGDiED+L t+A+++ +++F+  +  +++G K+  + ++R+YFGnWLRDY
  gi|1700996    45 HGDIEDILSTLAkkgagggFVLasmlgggGSKFNGLDIKRIYFGNWLRDY 94   

                   sqAvDvGsLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvt
                   sqAvD+ sLK  +  ti  +             vL F+a+GYAt EFEvt
  gi|1700996    95 SQAVDIASLKKLQLQTIINL-----------CMVLGFMAHGYATHEFEVT 133  

                   EERLGvYRPEEHiDnPkgYADikDARkfDaRLRGPvd.............
                    ERLGvY P EHiDnPkgY  ++D R++ + LR Pvd   ++ ++ + ++
  gi|1700996   134 AERLGVYLPTEHIDNPKGYGAGEDPRQYHPQLRPPVDvclssvtpvkmsh 183  

                   ....PrELEiDprsGmKnYiAnEslayqgGWnatsAGYvrfslaRaiHFG
                    +++PrELEiDpr+GmKnYiAnE+    g W  ts   vr  l+R+iH G
  gi|1700996   184 fsrqPRELEIDPRTGMKNYIANEQ----GHW-DTSKALVRRTLERCIHHG 228  

                   RLYtsGsrgkGkEsDLCEALRCLGqALHclEDFsAHsnYCELaLieleer
                   R      r  G  +D  EA R LGq LH+lEDF+AHsn+CELaL+ l   
  gi|1700996   229 RQH----RANGDKKDEYEAYRLLGQLLHTLEDFPAHSNFCELALVSL--- 271  

                   rgGyrdvFpHvGadteinlrndtrnnGkrvyPLvtGtFGavDFLHsvLGE
                     G+++vF HvG + +i        nGk v P+vtG FG+ DF+ s LGE
  gi|1700996   272 --GHQQVFVHVGDQVRIHA-----PNGKTVAPIVTGSFGSSDFIYSLLGE 314  

                   AtDHFtqsEvdEmdlALkaAeqaskssgGGdsrqRGlllfglnlgGsgss
                   A DH   + v +++  L  A  +s+  +  ++            gG+ ++
  gi|1700996   315 AGDHL--ASVSDLNKELDKARAKSQTQSR-SG-----P------GGAPAD 350  

                   gtDFi.sLvsqlPgvGdGlAstARsLkAasaAqEqqnsrqltranvnvfn
                    +D ++ L+  lPg  d   s  R+L                 +n+n + 
  gi|1700996   351 PADVLrDLLFSLPGGADSEMS--RDL-----------------DNINRIR 381  

                   appgstggppgpgvPGmsPnFDpvktakkiYPiLEFRDKivRsinnmieK
                   a p   g  p      msP+    +  + ++ +L FRD +v+ i  +i+ 
  gi|1700996   382 AGPSQGGKRPEE----MSPQ----ELHGVLWQVLTFRDSVVKKIAKTIQM 423  

                   iPGLEsLlEkisEtLtaFiLgLLAPFvRPiidqvskvLKeGssglieasA
                   iPGL  L+ ki + + +F+L  L PF++Pi++  +  L   s  +i+   
  gi|1700996   424 IPGLGPLIQKITDSINVFVLTTLEPFLKPILKSATGGLSAASGEVINN-- 471  

                   naqlEPWnnPrCddPtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilY
                   + q+E +n+ r  dPtHs LsKDHF  +Ln  AG  a  iv      ++ 
  gi|1700996   472 HDQYEVFNDSRVSDPTHSFLSKDHFNLILNEPAGHLARIIVVHAAGLVIK 521  

                   AwenPGvPvdEvlnDiLrvFHHPAardEevEihrkmfetvkkWirEt.kn
                    w+   v v  + ++iL+   HP  +d +  ++r+m + + +W+   + +
  gi|1700996   522 SWDDNSVNVHQISEEILQCLFHPDFHDKNSKVQREMMQYMADWVSKLgGK 571  

                   rhelnslLssEsvKeghnHvladq...ssdssrsvsagshtsnGadgGHG
                   +h   + Ls  +v+++ n  la++++ + +++    + +h    a+ G  
  gi|1700996   572 QHATLQRLSKQAVRNHENIRLAGDggaPASQGSFADSQAHNVQHALAGYA 621  

                   kvaGslWskikkr<-*
                   +     +s+ ++    
  gi|1700996   622 QSHIPGFSQAQSV    634  

gi|169845161|ref|XP_001829300.1|: domain 1 of 1, from 1 to 604: score 473.0, E = 4.3e-139
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma+  +      L++a v i LP +A AFGAG iP  A +  k +RH
  gi|1698451     1    MAF-TPSLTTTFLIVATVCILLP-RAHAFGAGDIPDFAYLNDKAFRH 45   

                   GDiEDvLKtvAFikG.......................kKWttmmvgRvY
                   GDiE vL ++A   G+   ++++     ++  +  ++++K+    +++vY
  gi|1698451    46 GDIESVLENLAKTAGraaigggnllafassvvsaatgpRKFNKNDIKKVY 95   

                   FGnWLRDYsqAvDvGsLKGvnAatiRiiaslsshlrralvWvLsFlafGY
                   FGnWLRDYsq +D+  L   +A t+ ++           v vL F++fG+
  gi|1698451    96 FGNWLRDYSQCMDIAGLSKLSAETLVLV-----------VSVLGFMTFGF 134  

                   AteEFEvtEERLGvYRPEEHiDnPkgYADik.DARkfDaRLRGPvdPrEL
                    teEFEvt ERLGvY P EHiDnPkgYA++++DAR++ ++LR PvdPrEL
  gi|1698451   135 STEEFEVTAERLGVYLPVEHIDNPKGYAEKEgDAREYHPKLRPPVDPREL 184  

                   EiDprsGmKnYiAnEslayqgGWnatsAGYvrfslaRaiHFGRLYtsGsr
                   EiDp++GmKnY+A E     +GW  ts G++r  l  +i +GR      r
  gi|1698451   185 EIDPETGMKNYMATEG----QGW-DTSTGFIRRTLRECIEYGR------R 223  

                   gkGkEs.DLCEALRCLGqALHclEDFsAHsnYCELaLieleerrgGyrdv
                     G E+ DL EA R LG  LH+lED  AHsn+CELaL+ +     Gy++v
  gi|1698451   224 ANGEENaDLWEAYRLLGTGLHTLEDLMAHSNWCELALRKM-----GYEEV 268  

                   FpHvGadteinlrndtrnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtq
                   F HvG +  +        nG    PLvtGtFG+ DFLHs LGEA D   q
  gi|1698451   269 FCHVGDNVLVDT-----PNGPAP-PLVTGTFGGADFLHSLLGEAGDKLSQ 312  

                   sEvdEmdlALkaAeqaskssgGGdsrqRGlllfglnlgGsgssgtDFisL
                   + v ++   L  A+q    sgG    + G l                  +
  gi|1698451   313 ASVTDLSGKLNEAQQ----SGG---ADLGPL----------------KNI 339  

                   vsqlPgvGdGlAstARsLkAasaAqEqqnsrqltranvnvfnappgstgg
                   +s++ g               s+  E+ n  +  ++ +  +   p     
  gi|1698451   340 LSRIMG-------------GSSEEEEKLNQGEEMKEAAQGYHFDPD---- 372  

                   ppgpgvPGmsPnFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLl
                              n  p ++ +k+  +L + D ++R +   ++ +PGL  Ll
  gi|1698451   373 -----------NIAPPEVQQKLLDLLKWHDDVMRNVTKKMAMVPGLNNLL 411  

                   EkisEtLtaFiLgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWn
                   E  s  L  +i  +LAP++ Pi+ q + vL eGs ++i++  + q+E + 
  gi|1698451   412 EEFSNALNGYIYTVLAPYLTPILAQATSVLDEGSKAVIDS--EDQYEVFD 459  

                   nPrCddPtHsmLsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvP
                   nP  +dP Hs+LsKDHF  +Ln  AG++a  iv   v  i+ Aw n   P
  gi|1698451   460 NPDAHDPSHSLLSKDHFGLILNEPAGKIAQIIVEHTVNHIVQAWYNDEDP 509  

                   vdEvlnDiLrvFHHPAardEevEihrkmfetvkkWirEtknrhelnsl..
                   ++ vln iL +FHHP     + E+++kmfe ++kWi      +  ++++ 
  gi|1698451   510 DS-VLNVILEAFHHPYYNTGNSEVQHKMFEHMQKWIGGLGPDEAAQTIea 558  

                   LssEsvKeghnHvladqssdssrsvsagshtsnGadgGHGkvaGslWski
                   L+ Esv+e++n  l ++ ++       ++++  G+ +   k++G   s  
  gi|1698451   559 LTKESVREHKNKRLGSEGHSFD----EPGYG--GCSHSY-KPSGGYSSGG 601  

                   kkr<-*
                    ++   
  gi|1698451   602 TNK    604  

gi|169782124|ref|XP_001825525.1|: domain 1 of 1, from 1 to 604: score 458.8, E = 8.2e-135
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                         +      + L+l+++L     +A AFGAGni si ++EG+nwRH
  gi|1697821     1    ---MSDTVQKLCLLLSLIL-AFSAQAHAFGAGNIASISRIEGQNWRH 43   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L t+   +  +G+K+  + v+RvYFGnWLRDYs AvDvG LK v
  gi|1697821    44 GDIEDALLTLFLARvagGRKFNKLDVQRVYFGNWLRDYSLAVDVGTLKYV 93   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteE.FEvtEERLGvYRPEE
                    A  iRi+           +WvL Fl+fG Ate +     +RLG+Y P E
  gi|1697821    94 GAEAIRIL-----------IWVLGFLSFGQATEFpHYASGDRLGCYEPTE 132  

                   HiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayq
                   HiDnP+gYA++   R     +   +d +   + p s +  Y+    ++ +
  gi|1697821   133 HIDNPLGYAEG---RMLGIMI---IDSGVQYVGPLSTLLYYVTCGIMTTE 176  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                   g   atsAG  r  + R+i  GR Y         ++DL EA R LG  LH
  gi|1697821   177 GVGIATSAGLARRVFCRSIQLGRQYAKSWN----DEDLHEAFRLLGTGLH 222  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clED++AHsnY EL Lie+     G +++ pHvG +t ++l    +    
  gi|1697821   223 CLEDYAAHSNYTELSLIEM-----GESEISPHVGRNTIVEL----HGAQN 263  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                    vyP+vtGtFG+vDF HsvLGE  D  tqsEv+     L++    s+s++
  gi|1697821   264 DVYPVVTGTFGGVDFFHSVLGELSDKVTQSEVQ----SLEGVITDSQSGS 309  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                     +s    ++                  L+s +P+ G    s+A   k +
  gi|1697821   310 PSES----FV----------------QDLLSMIPA-GLVDDSEAQANKME 338  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                         +n++q +++                           +     +k
  gi|1697821   339 EFKTQSENAKQYSQDVSLR--------------ELEEWTCYLEGLH--QK 372  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   iYP+LE+ D i++sin  ieKiP L  L+E+i + +t+F+ ++LAP+v P
  gi|1697821   373 IYPVLEWHDEIIKSINSAIEKIPVLPELVEQIQDHITVFVFSVLAPYVLP 422  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qv   L+ Gss +i++s ++q   + n    +PtHsmLsKDHF+nvL
  gi|1697821   423 IIKQVKVELQTGSSEVIQSSREQQHIVFENDESSNPTHSMLSKDHFSNVL 472  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar..
                   n  AGRva+ ++++ vP ++  w+   + +   l  i+ +vFHHPA+r++
  gi|1697821   473 NEPAGRVASEVIKWTVPQLMECWDSEDIDITRTLDRIIVgVFHHPALRen 522  

                   ..dEevEihrkmfetvkkWi..rEtknrhelnslLssEsvKeghnHvlad
                   ++d   ++++ mf tv++W +++ +++++ l++ L+   v eg+nH  ++
  gi|1697821   523 geDGAADVRQIMFHTVEEWWhgKTEEEQEHLREQLTRQGVFEGRNH-KEG 571  

                   qssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    ++  +    + +       gGHG +  s      +    
  gi|1697821   572 VHDTGH----GCGKPLVLRKGGHGNPLESNGTGPSSL    604  

gi|116180482|ref|XP_001220090.1|: domain 1 of 1, from 1 to 576: score 456.8, E = 3.1e-134
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma  ++      L+  +vL    ++  AFGAGni  i +vEG+nwRH
  gi|1161804     1    MATFKPYP---FLLGFIVLFCFVQPTLAFGAGNIAGISKVEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L  +A  +  +GkK+  +mv RvYFGnWLRDYsqA+DvG +K v
  gi|1161804    45 GDIEDALLRIAMARvagGKKFDKLMVSRVYFGNWLRDYSQAIDVGTVKAV 94   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                   +A  iR++             +L F++fGY   EFEvt ERLG+YRPE+H
  gi|1161804    95 SAEAIRLL-----------LCILGFVTFGYGSGEFEVTAERLGCYRPEDH 133  

                   iDnPkgYADikDARkfDaRLRGPvd.PrELEiDprsGmKnYiAnEslayq
                   iDnPk+YAD+ DA ++D+RLRG vd+  EL iD ++GmKnYiAnE     
  gi|1161804   134 IDNPKNYADNVDATDYDPRLRGLVDeSVELAIDEETGMKNYIANEN---- 179  

                   gGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALH
                    G   tsA  vr  + ++i  GR Y      k    +L EALR LG  LH
  gi|1161804   180 AGI-MTSAQHVRRLFSKCIRLGRSYGQSNNKK----ELYEALRLLGTGLH 224  

                   clEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGk
                   clE       Y   aL  +              Ga              +
  gi|1161804   225 CLEGV-----YLAAALLPI-------------PGAR-------------H 243  

                   rvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssg
                   +vyP+vtGtFG+vDFLHsv GE  D   qsE+++++  L   +q sks  
  gi|1161804   244 SVYPIVTGTFGGVDFLHSVTGELSDKMIQSEIEDLEGTL---QQSSKSDT 290  

                   GGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAa
                           ll                  L+ ++P   dGl       k  
  gi|1161804   291 S-------LL----------------RDLLDKIP---DGLLGGSDKSKID 314  

                   saAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                      q  q ++    +nv v             p  P     +    + k+
  gi|1161804   315 DIQQNAQAAQ---MENVSV------------SPREPEEFTRY-IQTIFKQ 348  

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   i P +EF D + + i   i+K+P L  ++E++ E + +F+  ++APF+ P
  gi|1161804   349 IMPAIEFHDELLKNISEAISKVPVLPKIIEQLEEQMSVFVFQIIAPFIIP 398  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   +i+q+ + L  G++ +i++s n+q   + +   +dPtHsmL+KDHFtn+L
  gi|1161804   399 VIEQIKNELATGATEIIQSSQNEQHIVFDDDDSTDPTHSMLAKDHFTNIL 448  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAard.
                   n   GR a+ +v + vP i+ Aw+   v vd  ln i+ +v HHPA+rd 
  gi|1161804   449 NEIGGRTASKVVSWSVPQIMDAWDDESVDVDQLLNKIIYgVLHHPAQRDm 498  

                   ..EevEihrkm.fetvkkWirEt..knrhelnslLssEsvKeghnHvlad
                   ++E  E  r++ f+ v++W ++ ++ +r+e++  Ls E v  g nH   +
  gi|1161804   499 gpEGAEEGRNLiFDMVREWWEDMgdAQREEYRGKLSREGVERGENH--RE 546  

                   qssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    + d +       h+  G +  H        + ++ r   
  gi|1161804   547 GQTDCG-------HGCGGKLKMHKNFRNEAEQTMEDR    576  

gi|238498984|ref|XP_002380727.1|: domain 1 of 1, from 1 to 561: score 423.7, E = 3e-124
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                           + ++  LL                GAGni si ++EG+nwRH
  gi|2384989     1    -----MSSSPTLL----------------GAGNIASISRIEGQNWRH 26   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGv
                   GDiED L t+   +  +G+K+  + v+RvYFGnWLRDYs AvDvG LK v
  gi|2384989    27 GDIEDALLTLFLARvagGRKFNKLDVQRVYFGNWLRDYSLAVDVGTLKYV 76   

                   nAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEH
                    A  iRi+           +W            EFEvt +RLG+Y P EH
  gi|2384989    77 GAEAIRIL-----------IW------------EFEVTTDRLGCYEPTEH 103  

                   iDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqg
                   iDnP+   D++               rEL +D  +G+KnYiA E      
  gi|2384989   104 IDNPL--VDEE---------------RELLVDSMTGLKNYIATEG----V 132  

                   GWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHc
                   G  atsAG  r  + R+i  GR Y         ++DL EA R LG  LHc
  gi|2384989   133 GI-ATSAGLARRVFCRSIQLGRQYAKSWN----DEDLHEAFRLLGTGLHC 177  

                   lEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkr
                   lED++AHsnY EL Lie+     G +++ pHvG +t ++l    +     
  gi|2384989   178 LEDYAAHSNYTELSLIEM-----GESEISPHVGRNTIVEL----HGAQND 218  

                   vyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgG
                   vyP+vtGtFG+vDF HsvLGE  D  tqsEv+     L++    s+s++ 
  gi|2384989   219 VYPVVTGTFGGVDFFHSVLGELSDKVTQSEVQ----SLEGVITDSQSGSP 264  

                   GdsrqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAas
                    +s    ++                  L+s +P+ G    s+A   k + 
  gi|2384989   265 SES----FV----------------QDLLSMIPA-GLVDDSEAQANKMEE 293  

                   aAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakki
                        +n++q +++                           +     +ki
  gi|2384989   294 FKTQSENAKQYSQDVSLR--------------ELEEWTCYLEGLH--QKI 327  

                   YPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRPi
                   YP+LE+ D i++sin  ieKiP L  L+E+i + +t+F+ ++LAP+v Pi
  gi|2384989   328 YPVLEWHDEIIKSINSAIEKIPVLPELVEQIQDHITVFVFSVLAPYVLPI 377  

                   idqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvLn
                   i+qv   L+ Gss +i++s ++q   + n    +PtHsmLsKDHF+nvLn
  gi|2384989   378 IKQVKVELQTGSSEVIQSSREQQHIVFENDESSNPTHSMLSKDHFSNVLN 427  

                   sCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHHPAar...
                     AGRva+ ++++ vP ++  w+n  + +   l  i+ +vFHHPA+r+ +
  gi|2384989   428 EPAGRVASEVIKWTVPQLMECWDNEDIDITRTLDRIIVgVFHHPALReyg 477  

                   .dEevEihrkmfetvkkWi..rEtknrhelnslLssEsvKeghnHvladq
                   +d   ++++ mf tv++W +++ +++++ l++ L+   v eg+nH  ++ 
  gi|2384989   478 eDGAADVRQIMFHTVEEWWhgKTEEEQEHLREQLTRQGVFEGRNH-KEGV 526  

                   ssdssrsvsagshtsnGadgGHG...kvaGslWskikkr<-*
                   ++  +    + +       gGHG++    G   s +++    
  gi|2384989   527 HDTGH----GCGKPLVLRKGGHGnslESNGTGPSSLEEA    561  

gi|46112807|ref|XP_383081.1|: domain 1 of 1, from 1 to 610: score 314.4, E = 2.3e-91
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m++        +L++++v +   ++  AFGAG +       G  wRH
  gi|4611280     1    MTF---SLTTKVLIVSLVCLLFAGRVSAFGAGEVAGTSSFNGYVWRH 44   

                   GDiEDvLKtv..AFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvn
                   GDi + L+ ++  F+   ++t++  + +YFGnWLRD+sq +D   L  v 
  gi|4611280    45 GDIAEALRYLpaSFVTHYRFTALERRQIYFGNWLRDFSQIIDTTGLETVP 94   

                   AatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHi
                    + +R i           v +L F+ fG+At+EF+vt ERLG+Y   EHi
  gi|4611280    95 EPVLRAI-----------VSILGFMEFGFATDEFDVTRERLGCYTHVEHI 133  

                   DnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgG
                   DnPkgY D+  A++ D RLRGPvdPrELE Dp++GmKnYiAn       G
  gi|4611280   134 DNPKGYPDN--AKDVDERLRGPVDPRELEFDPKTGMKNYIANSG----HG 177  

                   WnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHcl
                   W  tsA Yv   l  +i  GR     s+         EA   LG ALH+l
  gi|4611280   178 W-DTSADYVTRQLRECIRLGRDKDPKSKK--------EAFIHLGAALHTL 218  

                   EDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrv
                   EDFsAHsn+ EL L +l     G +dvF+ vG   +++       +G+ v
  gi|4611280   219 EDFSAHSNFTELCLQDL-----GESDVFAFVGDACRVQT---PGWRGRMV 260  

                   yPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGG
                    P+vtGtFG  D  Hs LGEA D      v      L+  e   + +   
  gi|4611280   261 PPIVTGTFGMLDIFHSLLGEADD----MAVLQCKGSLENLENEMNIGEIA 306  

                   dsrqRGlllfgln.lgGsgssgtDFisLvsqlPgvGdGlAstARsLkAas
                     +   +l  +++ l   +s+ t    ++ ql +vG  +     s kA  
  gi|4611280   307 FQHLYDILRAAIEaLSKLASNTTIHDPILQQLESVGVLFEKAEESKKAST 356  

                   aAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakki
                    A     ++     n  +                               i
  gi|4611280   357 TAESTLDAN-----NLWQ------------------------------TI 371  

                   YPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF....iLgLLAPF
                    Pi    D+i + i    e     E L E  s  L  ++++ +   L   
  gi|4611280   372 EPIFYLHDRIKKWIQERTETHDD-EPLSEDSSSQLGKYtdqlVFKYLSLM 420  

                   vRPiidqvskvLKeGssglieasAnaq.lEPWnnPrCddPtHsmLsKDHF
                   +   i q  ++LK     + + +A++ + E + +    dP Hs +sKDHF
  gi|4611280   421 IESSIMQLRNALKAAKERVDAEAAKSTsAEVYLDGEGSDPSHSDISKDHF 470  

                   tnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAa
                   +nvLn  AG v++    + +  ++  w+ P    +E +  iL + HHPA 
  gi|4611280   471 SNVLNQPAGLVSTVTTNWTTQQVVKCWDDPFRDEEESIRQILTIMHHPAF 520  

                   .rdEevEihrkmfetvkkWirEtk..nrhelnslLssEsvKe..ghnHvl
                   +   +  i++ mf  v++W +    ++++ ++ +L+ Esv+++++ nH l
  gi|4611280   521 pGRHKTPIQKYMFTAVEEWWNHNTasEKETIRGMLTKESVRNrqHENHTL 570  

                   adqssdssrsvsagshtsnGadgGH.GkvaGslWskikkr<-*
                     +  + +r   a   +s       + k++   W     +   
  gi|4611280   571 TLKDLEGKRKGVAEFPGSRPKIKQKpAKPSPLSWAVSTAK    610  

gi|256721170|gb|EEU34581.1|: domain 1 of 1, from 1 to 612: score 309.6, E = 6.3e-90
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      m+      +  L ++ +v +   ++A AFGAG +    +  G  wRH
  gi|2567211     1    MT----SASTKLFLVVLVCLLFAGRASAFGAGEVAGASEFNGYVWRH 43   

                   GDiEDvLKtv..AFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvn
                   GDi + L+ ++  F+   ++ t+  + +YFGnWLRD+sq +D   L  v 
  gi|2567211    44 GDIVEALRYLpaSFVTHYRFSTLERRQIYFGNWLRDFSQIIDTTGLENVP 93   

                   AatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHi
                    + +R i           v +L Fl fG+At+EFEvt ERLG+Y+  EHi
  gi|2567211    94 EPVLRAI-----------VSILGFLEFGFATDEFEVTRERLGCYKHVEHI 132  

                   DnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgG
                   DnPkgY D+  A++ D RLRGP+d rELE Dpr+GmKnYiA       +G
  gi|2567211   133 DNPKGYPDN--AKEVDERLRGPLDQRELEFDPRTGMKNYIASSG----KG 176  

                   WnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHcl
                   W  tsA Yv   l  +i  GR   + s+         EA   LG ALH+l
  gi|2567211   177 W-DTSADYVTTQLRECIRLGREKDAKSKK--------EAFIHLGAALHTL 217  

                   EDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrv
                   EDFsAHsn+ EL L el     G  dvF+ vG   ++        +G+ v
  gi|2567211   218 EDFSAHSNFTELCLHEL-----GEGDVFAFVGDACRVKA---PGWRGRMV 259  

                   yPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGG
                    P+vtGtFG  D  Hs LGEA D      v      L+  e   + +   
  gi|2567211   260 PPIVTGTFGMLDIFHSLLGEADD----MAVLQCKGSLENLENEMNIGEIA 305  

                   dsrqRGlllfgln.lgGsgssgtDFisLvsqlPgvGdGlAstARsLkAas
                     +   ll  +++ l   +++ t    ++ ql  vG  +       kA+ 
  gi|2567211   306 FQHLYDLLKAAIQaLSKLAANATISDPILKQLETVGVLFQ------KAEE 349  

                   aAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDpvktakki
                    A   + s+  t++++                         D+ +  + i
  gi|2567211   350 SANADKESQ--TAESG------------------------LDADQLWQSI 373  

                   YPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaF....iLgLLAPF
                    Pi    D+i + i    e+    E L E  s  L  ++++ +   L   
  gi|2567211   374 EPIFYLHDRIKKWIQERTEQHDA-EPLSEESSTQLGKYtdqlVFKYLSLM 422  

                   vRPiidqvskvLKeGssglieasAnaq.lEPWnnPrCddPtHsmLsKDHF
                   +   i q  ++LK     + + +A++ + E + +    dP Hs +sKDHF
  gi|2567211   423 IESSIMQLRNALKAAKERVDAEAAKSTsAEIYEDGDASDPSHSDISKDHF 472  

                   tnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAa
                   +nvLn  AG v++    + +  ++  w+      +E +  +L + HHPA 
  gi|2567211   473 SNVLNQPAGLVSTVTTNWTTQQVVKCWDDTFRDEEETIRQVLSILHHPAF 522  

                   .rdEevEihrkmfetvkkW..irEtknrhelnslLssEsvKe..ghnHvl
                   +   +  i++ mf+ v++W + +  +++ +++ +L+ +sv+++++ nH+l
  gi|2567211   523 pGRKKTPIQKYMFNAVEEWwhHNTAEEKSKIRGMLTKDSVRArqHENHSL 572  

                   adqssdssrsvsagshtsnGadgGH.GkvaGslWskikkr<-*
                     +  + ++   a   +s   +   + k++   W  ++ +   
  gi|2567211   573 TLKDLEGKKKGVAVFPGSRPKLRQKpAKPSPLTWVIVEAK    612  

gi|226283048|gb|EEH38614.1|: domain 1 of 1, from 1 to 519: score 259.5, E = 7.8e-75
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                      ma         +   +++ + L  +  AFGAGni si ++EG+nwRH
  gi|2262830     1    MAW---STTTTVAATCLLFLLLARPSHAFGAGNIASISKIEGQNWRH 44   

                   GDiEDvLKtvAFik...GkKWttmmvgRvYFGnWLR.....DYsqAvDvG
                   GDiEDv+ t+   ++ +GkK+  + v+R+YFGnWLR  +++DYsqA+D+G
  gi|2262830    45 GDIEDVILTLMMARsagGKKFSKIDVQRIYFGNWLRliprkDYSQAIDIG 94   

                   sLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvY
                    +K v+   iRi+             vL F++fGY t EFEvt ER+G+Y
  gi|2262830    95 TVKYVSVEAIRIL-----------LLVLGFMTFGYGTGEFEVTTERIGCY 133  

                   RPEEHiDnPkgYADikDARkfDaRLRGPvdP.rELEiDprsGmKnYiAnE
                    P EHiDnP+gY +++D R++  RLRGP+d +rEL iDpr+         
  gi|2262830   134 QPTEHIDNPLGYGEGEDPRRYHRRLRGPIDEqRELGIDPRT--------- 174  

                   slayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCL
                                                                     
  gi|2262830     - -------------------------------------------------- -    

                   GqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndt
                                                                     
  gi|2262830     - -------------------------------------------------- -    

                   rnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqa
                                    vDFLHsv+GE  D  tqsE++ ++  +   e+ 
  gi|2262830   175 -----------------VDFLHSVMGEISDKATQSEIQSLEGVIADSEKE 207  

                   skssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlP.gvGdGlAstA
                   +         q G+l                  L+ ++P+g+  G  s  
  gi|2262830   208 QL--------QEGFL----------------QNLLDKIPnGLFGGDDSGT 233  

                   RsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsPnFDp
                   +  + +s+Aq  +          n              p  P    n+  
  gi|2262830   234 KMNEFKSNAQSNKKRT------ENI------------SPREPEEWVNYLN 265  

                   vktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLL
                     + +++YP+LE+ D +++sin  ie iPGL  ++E++ E L +F+ ++L
  gi|2262830   266 -DVHQQVYPLLEWHDNLMKSINKAIETIPGLSDIVEQVQEQLNVFVFSVL 314  

                   APFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKD
                   AP+v Pii+qv   L+ Gss +i++s  +q+  +n+  C+dPtHsmLsKD
  gi|2262830   315 APYVLPIIKQVKFELQTGSSEVIQSSKAQQYNTFNDDYCTDPTHSMLSKD 364  

                   HFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLr.vFHH
                   HF+n+Ln  AG+ aa iv +vvP i+  w+   + vd  +n i+ +v HH
  gi|2262830   365 HFSNLLNEPAGKAAAEIVRWVVPQIMECWDDESIDVDRTMNRIISgVLHH 414  

                   PAardE....evEihrkmfetvkkWirEtknr..helnslLssEsvKegh
                   PA+rd ++++  +++ +mf  v+ W +E+ +r++  l+  Ls E v++g 
  gi|2262830   415 PALRDYgedgAKDMRLTMFCIVESWWNEQGRRgqDSLRRQLSREGVRNGD 464  

                   nH........vladqss...dssrsvsagshtsnGadgGHGkva.GslWs
                   nH+++ ++++ + +++++ + +s+ v++g+    G  g  Gk ++ s+ s
  gi|2262830   465 NHkpgvhdsgHGCGKPMtlpTRSHFVPGGAQDLFGLGGFSGKSSkQSMPS 514  

                   kikkr<-*
                   +i+k    
  gi|2262830   515 EIEKM    519  

gi|261356832|gb|EEY19260.1|: domain 1 of 1, from 1 to 327: score 166.3, E = 8.7e-47
                   *->magLrigwgsvLLvlavvLivLPdkAAAFGAGniPsiAqvEGknwRH
                                                                     
  gi|2613568     -    ----------------------------------------------- -    

                   GDiEDvLKtvAFikGkKWttmmvgRvYFGnWLRDYsqAvDvGsLKGvnAa
                                                                     
  gi|2613568     - -------------------------------------------------- -    

                   tiRiiaslsshlrralvWvLsFlafGYAteEFEvtEERLGvYRPEEHiDn
                                                                     
  gi|2613568     - -------------------------------------------------- -    

                   PkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnYiAnEslayqgGWn
                                                                     
  gi|2613568     - -------------------------------------------------- -    

                   atsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEALRCLGqALHclED
                                                                     
  gi|2613568     - -------------------------------------------------- -    

                   FsAHsnYCELaLieleerrgGyrdvFpHvGadteinlrndtrnnGkrvyP
                                                                     
  gi|2613568     - -------------------------------------------------- -    

                   LvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALkaAeqaskssgGGds
                                                 m+ AL  A+ ++k+   G+ 
  gi|2613568     1 ------------------------------MNAALINAQSLTKGEESGSR 20   

                   rqRGlllfglnlgGsgssgtDFisLvsqlPgvGdGlAstARsLkAasaAq
                    +RGl+        s+ s +DFisL+ qlPg+GdG+  +AR+L+A sa q
  gi|2613568    21 -DRGLF-----SSSSSKSSGDFISLIGQLPGIGDGFMKEARDLQASSAQQ 64   

                   Eqqnsrql....tranvnvfnappgstggppgpgvPGmsPnFDpvktakk
                   Eq+n+r ++  +tr+nvn+               +PGmsP+FDpvkta++
  gi|2613568    65 EQDNMRSRsafnTRDNVNQ---------------IPGMSPDFDPVKTAGR 99   

                   iYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFiLgLLAPFvRP
                   iYPiL FRDKiv++in  i+K+PGLE LlE+isEtLtaFiLgLLAPF+ P
  gi|2613568   100 IYPILQFRDKIVKAINRFIAKVPGLEKLLERISETLTAFILGLLAPFIQP 149  

                   iidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsmLsKDHFtnvL
                   ii+qvskvLKeGssgli asA++q+EPW nPrC dPtHsmLsKDHFtn+L
  gi|2613568   150 IIQQVSKVLKEGSSGLIGASAKSQFEPWDNPRCSDPTHSMLSKDHFTNIL 199  

                   nsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrvFHHPAardEe
                   nsCAGRva+ti+qY++PR+lYAwenPGvPvdEv+ D+Lr+FHHP  rd++
  gi|2613568   200 NSCAGRVASTILQYITPRVLYAWENPGVPVDEVVDDVLRAFHHPVMRDDR 249  

                   vEihrkmfetvkkWirEtknrhelnslLssEsvKeghnHvladqssdssr
                    Ei+ +mf+tv++W+   ++rhel +lL s svK+++nHvl++q  + s 
  gi|2613568   250 GEIQSNMFKTVREWADGHPRRHELSHLLNSQSVKDHKNHVLNQQTTSGS- 298  

                   svsagshtsnGadgGHGkvaGslWskikkr<-*
                     sa    s+G   GHGk+  slW++ik+r   
  gi|2613568   299 -RSAVDVHSCGGGLGHGKTKNSLWNQIKTR    327  

gi|242211740|ref|XP_002471707.1|: domain 1 of 1, from 1 to 423: score 5.3, E = 0.76
                   *->magLrigwgsvLLvlavvLivLPdkAA.AFGAGniPsiAqvEGknwR
                          +++   +L vl++++  + ++ A AFGAGniP  A +EGk +R
  gi|2422117     1    ----MPHHLLLLTVLCILVFCVSGNGAyAFGAGNIPGFAYLEGKAFR 43   

                   HGDiEDvLKtvA.....FikGk.......KWttmmvgRvYFGnWLRDYsq
                   HGDiED L +vA++ ++F  G   +++++K+  + ++RvYFGnWLRDYsq
  gi|2422117    44 HGDIEDALSEVAkraggFALGAligrggsKFGGLDIKRVYFGNWLRDYSQ 93   

                   AvDvGsLKGvnAatiRiiaslsshlrralvWvLsFlafGYAteEFEvtEE
                   AvDv  L                         L F + GYAteEFEvt E
  gi|2422117    94 AVDVAGLSK-----------------------LQFQSLGYATEEFEVTPE 120  

                   RLGvYRPEEHiDnPkgYADikDARkfDaRLRGPvdPrELEiDprsGmKnY
                   RLGvY P EHiDnPkgY   +DA ++ ++LRGPvdPrELEiD ++GmKnY
  gi|2422117   121 RLGVYLPTEHIDNPKGY--PNDAQRYHPKLRGPVDPRELEIDHHTGMKNY 168  

                   iAnEslayqgGWnatsAGYvrfslaRaiHFGRLYtsGsrgkGkEsDLCEA
                   iAn                +   + R+                       
  gi|2422117   169 IANGA--------------LLLYITRS----------------------- 181  

                   LRCLGqALHclEDFsAHsnYCELaLieleerrgGyrdvFpHvGadteinl
                        qA                 +++l                    n 
  gi|2422117   182 -----QA----------------SVVDL--------------------NA 190  

                   rndtrnnGkrvyPLvtGtFGavDFLHsvLGEAtDHFtqsEvdEmdlALka
                                                             E+d A   
  gi|2422117   191 ------------------------------------------ELDRARSK 198  

                   AeqaskssgGGdsrqRGlllfglnlgGsgssgtDFisLvsqlPgv.GdGl
                      +s+s+ G +s  R l                  sL+ +lP  +G+G 
  gi|2422117   199 SASQSRSGPG-SS--RSLA-------------DLLRSLLFKLPDTdGSG- 231  

                   AstARsLkAasaAqEqqnsrqltranvnvfnappgstggppgpgvPGmsP
                                 E +  + + ra++    appgs           msP
  gi|2422117   232 ---------GEMERELEGVE-RIRAQGYG--APPGSRRPED------MSP 263  

                   nFDpvktakkiYPiLEFRDKivRsinnmieKiPGLEsLlEkisEtLtaFi
                   +    +  + ++ +L FRD +++ i  +i                  +F+
  gi|2422117   264 Q----ELHAVLWQVLRFRDNVMKKITMVI------------------VFV 291  

                   LgLLAPFvRPiidqvskvLKeGssglieasAnaqlEPWnnPrCddPtHsm
                      L                               E +n+Pr +      
  gi|2422117   292 FTTL-------------------------------EVFNDPRAN------ 304  

                   LsKDHFtnvLnsCAGRvaativqYvvPRilYAwenPGvPvdEvlnDiLrv
                           +Ln  AG     i+ Y + R++ Aw+ P v    v  DiL+ 
  gi|2422117   305 -------LILNEPAGHLGKIILIYATTRVVKAWDDPSVNMHHVTDDILHC 347  

                   FHHPAardEevEihrkmfetvkkWirEtknrh.elnslLssEsvKeghnH
                     HP     +  i+ +m e ++ W++   ++++e+   L+  sv+++ n 
  gi|2422117   348 MFHPDFNTRNSPIQYEMMEYMRSWVQNLGHQQpEVLRRLTKQSVRNHLNM 397  

                   vladqssdssrsvsagshtsnGadgGHGkvaGslWskikkr<-*
                    l ++   s                GHG va     ++++    
  gi|2422117   398 RLGSEGAAST---------------GHGTVAQTAGMEVQND    423  


Histogram of all scores:
score    obs    exp  (one = represents 463 sequences)
-----    ---    ---
 -907      1      0|=                                                          
 -906      3      0|=                                                          
 -905      5      0|=                                                          
 -904     25      0|=                                                          
 -903     58      0|=                                                          
 -902    135      0|=                                                          
 -901    247      0|=                                                          
 -900    344      0|=                                                          
 -899    477      0|==                                                         
 -898    549      0|==                                                         
 -897    628      0|==                                                         
 -896    650      0|==                                                         
 -895    700      0|==                                                         
 -894    829      0|==                                                         
 -893    793      0|==                                                         
 -892    855      0|==                                                         
 -891    873      0|==                                                         
 -890    860      0|==                                                         
 -889    893      0|==                                                         
 -888    983      0|===                                                        
 -887   1067      0|===                                                        
 -886   1072      0|===                                                        
 -885   1174      0|===                                                        
 -884   1219      0|===                                                        
 -883   1257      0|===                                                        
 -882   1318      0|===                                                        
 -881   1274      0|===                                                        
 -880   1378      0|===                                                        
 -879   1343      0|===                                                        
 -878   1537      0|====                                                       
 -877   1504      0|====                                                       
 -876   1618      0|====                                                       
 -875   1729      0|====                                                       
 -874   1666      0|====                                                       
 -873   1861      0|=====                                                      
 -872   1925      0|=====                                                      
 -871   2079      0|=====                                                      
 -870   2138      0|=====                                                      
 -869   2310      0|=====                                                      
 -868   2425      0|======                                                     
 -867   2582      0|======                                                     
 -866   2734      0|======                                                     
 -865   2791      0|=======                                                    
 -864   3007      0|=======                                                    
 -863   3198      0|=======                                                    
 -862   3369      0|========                                                   
 -861   3569      0|========                                                   
 -860   3646      0|========                                                   
 -859   3773      0|=========                                                  
 -858   3944      0|=========                                                  
 -857   4275      0|==========                                                 
 -856   4452      0|==========                                                 
 -855   4732      0|===========                                                
 -854   4966      0|===========                                                
 -853   5399      0|============                                               
 -852   5782      0|=============                                              
 -851   6182      0|==============                                             
 -850   6503      0|===============                                            
 -849   7085      0|================                                           
 -848   7761      0|=================                                          
 -847   8294      0|==================                                         
 -846   8656      0|===================                                        
 -845   8974      0|====================                                       
 -844   9236      0|====================                                       
 -843   9564      0|=====================                                      
 -842   9618      0|=====================                                      
 -841   9717      0|=====================                                      
 -840  10055      0|======================                                     
 -839  10352      0|=======================                                    
 -838  10044      0|======================                                     
 -837  10147      0|======================                                     
 -836  10014      0|======================                                     
 -835  10202      0|=======================                                    
 -834  10241      0|=======================                                    
 -833  10191      0|=======================                                    
 -832  10176      0|======================                                     
 -831  10211      0|=======================                                    
 -830  10504      0|=======================                                    
 -829  10349      0|=======================                                    
 -828  10589      0|=======================                                    
 -827  10653      0|========================                                   
 -826  10888      0|========================                                   
 -825  11166      0|=========================                                  
 -824  11014      0|========================                                   
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 -247     54   4720|=         *                                                
 -246     40   4618|=        *                                                 
 -245     30   4518|=        *                                                 
 -244     28   4420|=        *                                                 
 -243     31   4324|=        *                                                 
 -242     19   4231|=        *                                                 
 -241     16   4139|=       *                                                  
 -240      9   4050|=       *                                                  
 -239     17   3962|=       *                                                  
 -238      8   3876|=       *                                                  
 -237     20   3792|=       *                                                  
 -236     27   3710|=       *                                                  
 -235      7   3629|=      *                                                   
 -234      9   3550|=      *                                                   
 -233     13   3473|=      *                                                   
 -232      3   3398|=      *                                                   
 -231      1   3324|=      *                                                   
 -230      4   3252|=      *                                                   
 -229      5   3181|=     *                                                    
 -228      6   3112|=     *                                                    
 -227      2   3044|=     *                                                    
 -226      3   2978|=     *                                                    
 -225      1   2913|=     *                                                    
 -224      0   2850|      *                                                    
 -223      0   2788|      *                                                    
 -222      1   2727|=    *                                                     
 -221      0   2667|     *                                                     
 -220      1   2609|=    *                                                     
 -219      0   2552|     *                                                     
>-218    104      -|=                                                          


% Statistical details of theoretical EVD fit:
              mu =  -422.1384
          lambda =     0.0223
chi-sq statistic = 382618880.0000
  P(chi-square)  =          0

Total sequences searched: 10818955

Whole sequence top hits:
tophits_s report:
     Total hits:           88
     Satisfying E cutoff:  87
     Total memory:         32K

Domain top hits:
tophits_s report:
     Total hits:           88
     Satisfying E cutoff:  88
     Total memory:         229K
